Augustus Richard Whorton - Publications

Affiliations: 
Duke University, Durham, NC 
Area:
nitric oxide
Website:
https://medicine.duke.edu/faculty/augustus-richard-whorton

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lin L, Xu C, Carraway MS, Piantadosi CA, Whorton AR, Li S. RhoA inactivation by S-nitrosylation regulates vascular smooth muscle contractive signaling. Nitric Oxide : Biology and Chemistry. PMID 29355776 DOI: 10.1016/j.niox.2018.01.007  1
2013 Devarie-Baez NO, Zhang D, Li S, Whorton AR, Xian M. Direct methods for detection of protein S-nitrosylation. Methods (San Diego, Calif.). 62: 171-6. PMID 23639867 DOI: 10.1016/j.ymeth.2013.04.018  1
2012 Liu C, Peng B, Li S, Park CM, Whorton AR, Xian M. Reaction based fluorescent probes for hydrogen sulfide. Organic Letters. 14: 2184-7. PMID 22486842 DOI: 10.1021/ol3008183  1
2012 Li S, Wang H, Xian M, Whorton AR. Identification of protein nitrosothiols using phosphine-mediated selective reduction. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 26: 20-6. PMID 22100619 DOI: 10.1016/j.niox.2011.11.001  1
2011 Liu C, Pan J, Li S, Zhao Y, Wu LY, Berkman CE, Whorton AR, Xian M. Capture and visualization of hydrogen sulfide by a fluorescent probe. Angewandte Chemie (International Ed. in English). 50: 10327-9. PMID 21898737 DOI: 10.1002/anie.201104305  1
2010 Zhang J, Li S, Zhang D, Wang H, Whorton AR, Xian M. Reductive ligation mediated one-step disulfide formation of S-nitrosothiols. Organic Letters. 12: 4208-11. PMID 20731371 DOI: 10.1021/ol101863s  1
2010 Brahmajothi MV, Mason SN, Whorton AR, McMahon TJ, Auten RL. Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium. Free Radical Biology & Medicine. 49: 294-300. PMID 20423728 DOI: 10.1016/j.freeradbiomed.2010.04.020  0.01
2008 Granillo OM, Brahmajothi MV, Li S, Whorton AR, Mason SN, McMahon TJ, Auten RL. Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L38-43. PMID 18441097 DOI: 10.1152/ajplung.00280.2007  1
2008 Zhu J, Li S, Marshall ZM, Whorton AR. A cystine-cysteine shuttle mediated by xCT facilitates cellular responses to S-nitrosoalbumin. American Journal of Physiology. Cell Physiology. 294: C1012-20. PMID 18287333 DOI: 10.1152/ajpcell.00411.2007  1
2008 Buckley BJ, Li S, Whorton AR. Keap1 modification and nuclear accumulation in response to S-nitrosocysteine. Free Radical Biology & Medicine. 44: 692-8. PMID 18062931 DOI: 10.1016/j.freeradbiomed.2007.10.055  1
2007 Li S, Whorton AR. Functional characterization of two S-nitroso-L-cysteine transporters, which mediate movement of NO equivalents into vascular cells. American Journal of Physiology. Cell Physiology. 292: C1263-71. PMID 17092994 DOI: 10.1152/ajpcell.00382.2006  1
2005 Yu CX, Li S, Whorton AR. Redox regulation of PTEN by S-nitrosothiols Molecular Pharmacology. 68: 847-854. PMID 15967877 DOI: 10.1124/mol.104.010504  1
2005 Li S, Whorton AR. Identification of stereoselective transporters for S-nitroso-L-cysteine: role of LAT1 and LAT2 in biological activity of S-nitrosothiols. The Journal of Biological Chemistry. 280: 20102-10. PMID 15769744 DOI: 10.1074/jbc.M413164200  1
2004 Brar SS, Grigg C, Wilson KS, Holder WD, Dreau D, Austin C, Foster M, Ghio AJ, Whorton AR, Stowell GW, Whittall LB, Whittle RR, White DP, Kennedy TP. Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease. Molecular Cancer Therapeutics. 3: 1049-60. PMID 15367699  1
2003 Suliman HB, Carraway MS, Welty-Wolf KE, Whorton AR, Piantadosi CA. Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. The Journal of Biological Chemistry. 278: 41510-8. PMID 12902348 DOI: 10.1074/jbc.M304719200  1
2003 Buckley BJ, Marshall ZM, Whorton AR. Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium. Biochemical and Biophysical Research Communications. 307: 973-9. PMID 12878207  1
2003 Brar SS, Corbin Z, Kennedy TP, Hemendinger R, Thornton L, Bommarius B, Arnold RS, Whorton AR, Sturrock AB, Huecksteadt TP, Quinn MT, Krenitsky K, Ardie KG, Lambeth JD, Hoidal JR. NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. American Journal of Physiology. Cell Physiology. 285: C353-69. PMID 12686516 DOI: 10.1152/ajpcell.00525.2002  1
2003 Li S, Whorton AR. Regulation of protein tyrosine phosphatase 1B in intact cells by S-nitrosothiols. Archives of Biochemistry and Biophysics. 410: 269-79. PMID 12573287  1
2002 Li S, Whorton AR. An assay for oxidant regulation of protein tyrosine phosphatase activity. Analytical Biochemistry. 303: 217-20. PMID 11950225 DOI: 10.1006/abio.2002.5592  1
2002 Carraway MS, Ghio AJ, Suliman HB, Carter JD, Whorton AR, Piantadosi CA. Carbon monoxide promotes hypoxic pulmonary vascular remodeling. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L693-702. PMID 11880294 DOI: 10.1152/ajplung.00211.2001  1
2002 Piantadosi CA, Tatro LG, Whorton AR. Nitric oxide and differential effects of ATP on mitochondrial permeability transition. Nitric Oxide : Biology and Chemistry. 6: 45-60. PMID 11829534 DOI: 10.1006/niox.2001.0368  1
2001 Demchenko IT, Boso AE, Whorton AR, Piantadosi CA. Nitric oxide production is enhanced in rat brain before oxygen-induced convulsions. Brain Research. 917: 253-61. PMID 11640911  1
2000 Demchenko IT, Boso AE, Bennett PB, Whorton AR, Piantadosi CA. Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide. Nitric Oxide : Biology and Chemistry. 4: 597-608. PMID 11139368 DOI: 10.1006/niox.2000.0313  1
2000 Buckley BJ, Whorton AR. Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells. American Journal of Physiology. Cell Physiology. 279: C1168-76. PMID 11003597 DOI: 10.1152/ajpcell.2000.279.4.C1168  1
1999 Brar SS, Kennedy TP, Whorton AR, Murphy TM, Chitano P, Hoidal JR. Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. The Journal of Biological Chemistry. 274: 20017-26. PMID 10391952 DOI: 10.1074/jbc.274.28.20017  1
1999 Li H, Marshall ZM, Whorton AR. Stimulation of cystine uptake by nitric oxide: regulation of endothelial cell glutathione levels. The American Journal of Physiology. 276: C803-11. PMID 10199810  1
1998 Padgett CM, Whorton AR. Cellular responses to nitric oxide: role of protein S-thiolation/dethiolation. Archives of Biochemistry and Biophysics. 358: 232-42. PMID 9784235 DOI: 10.1006/abbi.1998.0859  1
1998 Dashtaki R, Whorton AR, Murphy TM, Chitano P, Reed W, Kennedy TP. Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. The Journal of Pharmacology and Experimental Therapeutics. 285: 876-83. PMID 9580639  1
1997 Buckley BJ, Whorton AR. Tunicamycin increases intracellular calcium levels in bovine aortic endothelial cells. The American Journal of Physiology. 273: C1298-305. PMID 9357774  1
1997 Kantrow SP, Huang YCT, Whorton AR, Grayck EN, Knight JM, Millington DS, Piantadosi CA. Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung American Journal of Physiology - Lung Cellular and Molecular Physiology. 272. PMID 9227519  1
1997 Whorton AR, Simonds DB, Piantadosi CA. Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells. The American Journal of Physiology. 272: L1161-6. PMID 9227518 DOI: 10.1152/ajplung.1997.272.6.L1161  1
1997 Padgett CM, Whorton AR. Glutathione redox cycle regulates nitric oxide-mediated glyceraldehyde-3-phosphate dehydrogenase inhibition. The American Journal of Physiology. 272: C99-108. PMID 9038816 DOI: 10.1152/ajpcell.1997.272.1.C99  1
1996 Lindberg RA, Dewhirst MW, Buckley BJ, Hughes CS, Whorton AR. Ca2+-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells American Journal of Physiology - Cell Physiology. 271. PMID 8760062  1
1995 Padgett CM, Whorton AR. Regulation of cellular thiol redox status by nitric oxide. Cell Biochemistry and Biophysics. 27: 157-77. PMID 9279455  1
1995 Buckley BJ, Whorton AR. Arachidonic acid stimulates protein tyrosine phosphorylation in vascular cells. The American Journal of Physiology. 269: C1489-95. PMID 8572178 DOI: 10.1152/ajpcell.1995.269.6.C1489  1
1995 Buckley BJ, Mirza Z, Whorton AR. Regulation of Ca(2+)-dependent nitric oxide synthase in bovine aortic endothelial cells. The American Journal of Physiology. 269: C757-65. PMID 7573407 DOI: 10.1152/ajpcell.1995.269.3.C757  1
1995 Padgett CM, Whorton AR. S-nitrosoglutathione reversibly inhibits GAPDH by S-nitrosylation. The American Journal of Physiology. 269: C739-49. PMID 7573405 DOI: 10.1152/ajpcell.1995.269.3.C739  1
1994 Buckley BJ, Whorton AR. Ca(2+)-independent arachidonic acid release by vascular endothelium requires protein synthesis de novo. The Biochemical Journal. 300: 449-55. PMID 8002950  1
1993 Wang OL, Xuan YT, Mirza Z, Whorton AR. Effect of temperature on bradykinin-induced arachidonate release and calcium mobilization in vascular endothelial cells. The Biochemical Journal. 291: 803-9. PMID 8489507  1
1993 Huang YC, Kennedy TP, Su YF, Watkins WD, Whorton AR, Piantadosi CA. Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 74: 251-8. PMID 8444700 DOI: 10.1152/jappl.1993.74.1.251  1
1993 Wu NZ, Da D, Rudoll TL, Needham D, Whorton AR, Dewhirst MW. Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. Cancer Research. 53: 3765-70. PMID 8339289  1
1993 Kinnula VL, Mirza Z, Crapo JD, Whorton AR. Modulation of hydrogen peroxide release from vascular endothelial cells by oxygen. American Journal of Respiratory Cell and Molecular Biology. 9: 603-9. PMID 8257592 DOI: 10.1165/ajrcmb/9.6.603  1
1993 Qu Y, Campbell DL, Whorton AR, Strauss HC. Modulation of basal L-type Ca2+ current by adenosine in ferret isolated right ventricular myocytes Journal of Physiology. 471: 269-293. PMID 8120807  1
1992 Dolor RJ, Hurwitz LM, Mirza Z, Strauss HC, Whorton AR. Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool. The American Journal of Physiology. 262: C171-81. PMID 1531101 DOI: 10.1152/ajpcell.1992.262.1.C171  1
1992 Todd NW, Hunt CM, Kennedy TP, Piantadosi CA, Whorton AR. Effects of inhibition and induction of cytochrome P-450 isozymes on hyperoxic lung injury in rats American Journal of Respiratory Cell and Molecular Biology. 7: 222-229. PMID 1497908  1
1992 Ghio AJ, Kennedy TP, Whorton AR, Crumbliss AL, Hatch GE, Hoidal JR. Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. The American Journal of Physiology. 263: L511-8. PMID 1332500  1
1991 Campbell DL, Strauss HC, Whorton AR. Voltage dependence of bovine pulmonary artery endothelial cell function Journal of Molecular and Cellular Cardiology. 23: 133-144. PMID 1903817 DOI: 10.1016/0022-2828(91)90032-H  1
1991 Buckley BJ, Kent RS, Whorton AR. Regulation of endothelial cell prostaglandin synthesis by glutathione. The Journal of Biological Chemistry. 266: 16659-66. PMID 1885596  1
1991 Buckley BJ, Barchowsky A, Dolor RJ, Whorton AR. Regulation of arachidonic acid release in vascular endothelium. Ca2+-dependent and -independent pathways Biochemical Journal. 280: 281-287. PMID 1747101  1
1990 Middleton JP, Raymond JR, Whorton AR, Dennis VW. Short-term regulation of Na+/K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cells Journal of Clinical Investigation. 86: 1799-1805. PMID 2174907  1
1990 Dolor RJ, Strauss HC, Whorton AR. Mechanism of calcium influx in endothelial cells: role of intracellular calcium. Transactions of the Association of American Physicians. 103: 38-47. PMID 2151902  1
1989 Barchowsky A, Tabrizi K, Kent RS, Whorton AR. Inhibition of prostaglandin synthesis after metabolism of menadione by cultured porcine endothelial cells Journal of Clinical Investigation. 83: 1153-1159. PMID 2495300  1
1987 Barchowsky A, Kent RS, Whorton AR. Recovery of porcine aortic endothelial cell prostaglandin synthesis following inhibition by sublethal concentrations of hydrogen peroxide Bba - Molecular Cell Research. 927: 372-381. PMID 3101745 DOI: 10.1016/0167-4889(87)90102-9  1
1987 Barchowsky A, Data JL, Whorton AR. Inhibition of renin release by analogues of adenosine in rabbit renal cortical slices Hypertension. 9: 619-623. PMID 3034778  1
1986 Lambert TL, Kent RS, Whorton AR. Bradykinin stimulation of inositol polyphosphate production in porcine aortic endothelial cells. The Journal of Biological Chemistry. 261: 15288-93. PMID 3771575  1
1985 Whorton AR, Montgomery ME, Kent RS. Effect of hydrogen peroxide on prostaglandin production and cellular integrity in cultured porcine aortic endothelial cells. The Journal of Clinical Investigation. 76: 295-302. PMID 2991339 DOI: 10.1172/JCI111960  1
1985 Whorton AR, Collawn JB, Montgomery ME, Young SL, Kent RS. Arachidonic acid metabolism in cultured aortic endothelial cells. Effect of cAMP and 3-isobutyl-1-methylxanthine. Biochemical Pharmacology. 34: 119-23. PMID 2578280  1
1984 Whorton AR, Willis CE, Kent RS, Young SL. The role of calcium in the regulation of prostacyclin synthesis by porcine aortic endothelial cells. Lipids. 19: 17-24. PMID 6423923 DOI: 10.1007/BF02534603  1
1984 Barchowsky A, Data JL, Whorton AR. The effect of prostaglandin synthesis inhibition on the direct stimulation of renin release from rabbit renal cortical slices Prostaglandins. 27: 51-67. PMID 6324290 DOI: 10.1016/0090-6980(84)90220-X  1
1983 Kent RS, Diedrich SL, Whorton AR. Regulation of vascular prostaglandin synthesis by metabolites of arachidonic acid in perfused rabbit aorta. The Journal of Clinical Investigation. 72: 455-65. PMID 6409932  1
1982 Whorton AR, Young SL, Data JL, Barchowsky A, Kent RS. Mechanism of bradykinin-stimulated prostacyclin synthesis in porcine aortic endothelial cells. Biochimica Et Biophysica Acta. 712: 79-87. PMID 6810948 DOI: 10.1016/0005-2760(82)90087-X  1
1981 Kent RS, Kitchell BB, Shand DG, Whorton AR. The ability of vascular tissue to produce prostacyclin decreases with age. Prostaglandins. 21: 483-90. PMID 7015417  1
1980 Lazar JD, Whorton AR. Prostaglandin mediation of potassium effects on renin release Life Sciences. 27: 1327-1333. PMID 6777616 DOI: 10.1016/0024-3205(80)90227-1  1
1979 Whorton AR, Sweetman BJ, Oates JA. Application of high performance liquid chromatography and gas chromatography-Mass spectrometry to analysis of prostaglandin E1 in biological media Analytical Biochemistry. 98: 455-463. PMID 496011 DOI: 10.1016/0003-2697(79)90167-2  1
1977 Coniglio JG, Whorton AR, Beckman JK. Essential fatty acids in testes. Advances in Experimental Medicine and Biology. 83: 575-89. PMID 920484  1
1977 Whorton AR, Coniglio JG. Fatty acid synthesis in testes of fat-deficient and fat-supplemented rats. The Journal of Nutrition. 107: 79-86. PMID 13168 DOI: 10.1093/jn/107.1.79  1
1976 Whorton AR, Antalis T, Coniglio JG. The metabolism of (1-14C) stearic acid in rat testicular tissue. Biochimica Et Biophysica Acta. 424: 66-72. PMID 1252481  1
1975 Whorton AR, Coniglio JG. Studies in vitro of lipogenesis in rat testicular tissue. Lipids. 10: 783-9. PMID 1621  1
1971 Evans OB, Zseltvay R, Whorton R, Coniglio JG. Fatty acid synthesis in rat testes injected intratesticularly or incubated with 1- 14 C Acetate 1. Lipids. 6: 706-11. PMID 5141494  0.52
1971 Coniglio JG, Zseltvay RR, Whorton RA. Biosynthesis of stearic acid in rat testis. Biochimica Et Biophysica Acta. 239: 374-5. PMID 5113499  1
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