Carl Frederick Ware - Publications

Affiliations: 
1982-1996 University of California, Riverside, Riverside, CA, United States 
Area:
Immunology
Website:
https://sdbri.org/people/carl-f-ware/

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cheung TC, Atwell S, Bafetti L, Cuenca PD, Froning K, Hendle J, Hickey M, Ho C, Huang J, Lieu R, Lim S, Lippner D, Obungu V, Ward-Kavanagh L, Weichert K, ... Ware CF, et al. Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA. Structure (London, England : 1993). PMID 37279757 DOI: 10.1016/j.str.2023.05.011  0.341
2022 Stienne C, Virgen-Slane R, Elmén L, Veny M, Huang S, Nguyen J, Chappell E, Balmert MO, Shui JW, Hurchla MA, Kronenberg M, Peterson SN, Murphy KM, Ware CF, Šedý JR. Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa. Cell Reports. 38: 110553. PMID 35320716 DOI: 10.1016/j.celrep.2022.110553  0.326
2020 Garancher A, Suzuki H, Haricharan S, Chau LQ, Masihi MB, Rusert JM, Norris PS, Carrette F, Romero MM, Morrissy SA, Skowron P, Cavalli FMG, Farooq H, Ramaswamy V, Jones SJM, ... ... Ware CF, et al. Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma. Nature Neuroscience. PMID 32424282 DOI: 10.1038/S41593-020-0628-4  0.316
2019 Mintz MA, Felce JH, Chou MY, Mayya V, Xu Y, Shui JW, An J, Li Z, Marson A, Okada T, Ware CF, Kronenberg M, Dustin ML, Cyster JG. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. PMID 31204070 DOI: 10.1016/J.Immuni.2019.05.022  0.338
2017 Schaeuble K, Britschgi MR, Scarpellino L, Favre S, Xu Y, Koroleva E, Lissandrin TKA, Link A, Matloubian M, Ware CF, Nedospasov SA, Tumanov AV, Cyster JG, Luther SA. Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells. Cell Reports. 21: 2500-2514. PMID 29186687 DOI: 10.1016/J.Celrep.2017.10.119  0.316
2017 Colbeck EJ, Jones E, Hindley JP, Smart K, Schulz R, Browne M, Cutting S, Williams A, Parry L, Godkin A, Ware CF, Ager A, Gallimore A. Treg Depletion Licenses T Cell-Driven HEV Neogenesis and Promotes Tumor Destruction. Cancer Immunology Research. PMID 28947544 DOI: 10.1158/2326-6066.CIR-17-0131  0.312
2014 Bekiaris V, Šedý JR, Ware CF. Mixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells. Frontiers in Immunology. 5: 654. PMID 25566265 DOI: 10.3389/fimmu.2014.00654  0.381
2014 Šedý J, Bekiaris V, Ware CF. Tumor necrosis factor superfamily in innate immunity and inflammation. Cold Spring Harbor Perspectives in Biology. 7: a016279. PMID 25524549 DOI: 10.1101/cshperspect.a016279  0.355
2013 Bekiaris V, Sedý JR, Macauley MG, Rhode-Kurnow A, Ware CF. The inhibitory receptor BTLA controls γδ T cell homeostasis and inflammatory responses. Immunity. 39: 1082-94. PMID 24315996 DOI: 10.1016/j.immuni.2013.10.017  0.35
2013 Steinberg MW, Huang Y, Wang-Zhu Y, Ware CF, Cheroutre H, Kronenberg M. BTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infection. Plos One. 8: e77992. PMID 24205057 DOI: 10.1371/Journal.Pone.0077992  0.31
2013 Flynn R, Hutchinson T, Murphy KM, Ware CF, Croft M, Salek-Ardakani S. CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA. Plos One. 8: e77991. PMID 24205056 DOI: 10.1371/journal.pone.0077991  0.302
2013 Å edý JR, Bjordahl RL, Bekiaris V, Macauley MG, Ware BC, Norris PS, Lurain NS, Benedict CA, Ware CF. CD160 activation by herpesvirus entry mediator augments inflammatory cytokine production and cytolytic function by NK cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 828-36. PMID 23761635 DOI: 10.4049/jimmunol.1300894  0.368
2012 del Rio ML, Jones ND, Buhler L, Norris P, Shintani Y, Ware CF, Rodriguez-Barbosa JI. Selective blockade of herpesvirus entry mediator-B and T lymphocyte attenuator pathway ameliorates acute graft-versus-host reaction. Journal of Immunology (Baltimore, Md. : 1950). 188: 4885-96. PMID 22490863 DOI: 10.4049/jimmunol.1103698  0.311
2011 Cohavy O, Shih DQ, Doherty TM, Ware CF, Targan SR. CD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING. European Journal of Microbiology & Immunology. 1: 70-79. PMID 22348196 DOI: 10.1556/Eujmi.1.2011.1.9  0.305
2011 Sato-Hashimoto M, Saito Y, Ohnishi H, Iwamura H, Kanazawa Y, Kaneko T, Kusakari S, Kotani T, Mori M, Murata Y, Okazawa H, Ware CF, Oldenborg PA, Nojima Y, Matozaki T. Signal regulatory protein α regulates the homeostasis of T lymphocytes in the spleen. Journal of Immunology (Baltimore, Md. : 1950). 187: 291-7. PMID 21632712 DOI: 10.4049/jimmunol.1100528  0.301
2011 Soroosh P, Doherty TA, So T, Mehta AK, Khorram N, Norris PS, Scheu S, Pfeffer K, Ware C, Croft M. Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations. The Journal of Experimental Medicine. 208: 797-809. PMID 21402741 DOI: 10.1084/jem.20101562  0.317
2011 Arens R, Loewendorf A, Her MJ, Schneider-Ohrum K, Shellam GR, Janssen E, Ware CF, Schoenberger SP, Benedict CA. B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence. Journal of Virology. 85: 390-6. PMID 20980516 DOI: 10.1128/JVI.01839-10  0.306
2009 Cheung TC, Oborne LM, Steinberg MW, Macauley MG, Fukuyama S, Sanjo H, D'Souza C, Norris PS, Pfeffer K, Murphy KM, Kronenberg M, Spear PG, Ware CF. T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment. Journal of Immunology (Baltimore, Md. : 1950). 183: 7286-96. PMID 19915044 DOI: 10.4049/jimmunol.0902490  0.362
2009 Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, et al. Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia. British Journal of Pharmacology. 158: 1183-95. PMID 19775282 DOI: 10.1111/j.1476-5381.2009.00389.x  0.331
2009 Ware CF. Targeting the LIGHT-HVEM pathway. Advances in Experimental Medicine and Biology. 647: 146-55. PMID 19760072 DOI: 10.1007/978-0-387-89520-8_10  0.335
2009 Cheung TC, Steinberg MW, Oborne LM, Macauley MG, Fukuyama S, Sanjo H, D'Souza C, Norris PS, Pfeffer K, Murphy KM, Kronenberg M, Spear PG, Ware CF. Unconventional ligand activation of herpesvirus entry mediator signals cell survival. Proceedings of the National Academy of Sciences of the United States of America. 106: 6244-9. PMID 19332782 DOI: 10.1073/pnas.0902115106  0.394
2009 Cohavy O, Shih DQ, Doherty TM, Ware C, Targan SR. S1678 CD161 Defines Effector T Cell Population That Express Light, Respond to TL1A-DR3 Signaling, and Activates Antigen Presenting Cells Gastroenterology. 136: A-248. DOI: 10.1016/S0016-5085(09)61124-0  0.327
2009 Ware CF. Targeting the LIGHT-HVEM pathway Advances in Experimental Medicine and Biology. 647: 146-155. DOI: 10.1007/978-0-387-89520-8_10  0.33
2008 Ware CF. Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways Immunological Reviews. 223: 186-201. PMID 18613837 DOI: 10.1111/j.1600-065X.2008.00629.x  0.351
2008 Steinberg MW, Turovskaya O, Shaikh RB, Kim G, McCole DF, Pfeffer K, Murphy KM, Ware CF, Kronenberg M. A crucial role for HVEM and BTLA in preventing intestinal inflammation. The Journal of Experimental Medicine. 205: 1463-76. PMID 18519647 DOI: 10.1084/jem.20071160  0.329
2008 Vu F, Dianzani U, Ware CF, Mak T, Gommerman JL. ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction. Journal of Immunology (Baltimore, Md. : 1950). 180: 2284-93. PMID 18250437  0.33
2007 Elewaut D, Ware CF. The unconventional role of LT alpha beta in T cell differentiation. Trends in Immunology. 28: 169-75. PMID 17336158 DOI: 10.1016/J.It.2007.02.005  0.337
2006 Benedict CA, De Trez C, Schneider K, Ha S, Patterson G, Ware CF. Specific remodeling of splenic architecture by cytomegalovirus. Plos Pathogens. 2: e16. PMID 16518465 DOI: 10.1371/journal.ppat.0020016  0.305
2005 Iversen AC, Norris PS, Ware CF, Benedict CA. Human NK cells inhibit cytomegalovirus replication through a noncytolytic mechanism involving lymphotoxin-dependent induction of IFN-beta. Journal of Immunology (Baltimore, Md. : 1950). 175: 7568-74. PMID 16301666  0.325
2005 Nishimoto H, Lee SW, Hong H, Potter KG, Maeda-Yamamoto M, Kinoshita T, Kawakami Y, Mittler RS, Kwon BS, Ware CF, Croft M, Kawakami T. Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood. 106: 4241-8. PMID 16123219 DOI: 10.1182/blood-2005-04-1358  0.309
2005 Cohavy O, Zhou J, Ware CF, Targan SR. LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling. Journal of Immunology (Baltimore, Md. : 1950). 174: 646-53. PMID 15634882 DOI: 10.4049/Jimmunol.174.2.646  0.371
2005 Sedy JR, Gavrieli M, Potter KG, Hurchla MA, Lindsley RC, Hildner K, Scheu S, Pfeffer K, Ware CF, Murphy TL, Murphy KM. B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nature Immunology. 6: 90-8. PMID 15568026 DOI: 10.1038/ni1144  0.344
2004 Cohavy O, Zhou J, Granger SW, Ware CF, Targan SR. LIGHT expression by mucosal T cells may regulate IFN-gamma expression in the intestine. Journal of Immunology (Baltimore, Md. : 1950). 173: 251-8. PMID 15210782 DOI: 10.4049/Jimmunol.173.1.251  0.365
2003 Elewaut D, Shaikh RB, Hammond KJ, De Winter H, Leishman AJ, Sidobre S, Turovskaya O, Prigozy TI, Ma L, Banks TA, Lo D, Ware CF, Cheroutre H, Kronenberg M. NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. The Journal of Experimental Medicine. 197: 1623-33. PMID 12810685 DOI: 10.1084/jem.20030141  0.357
2003 Granger SW, Ware CF. Lymphotoxins The Cytokine Handbook. 825-835. DOI: 10.1016/B978-012689663-3/50038-7  0.35
2001 Shaikh RB, Santee S, Granger SW, Butrovich K, Cheung T, Kronenberg M, Cheroutre H, Ware CF. Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction. Journal of Immunology (Baltimore, Md. : 1950). 167: 6330-7. PMID 11714797 DOI: 10.4049/jimmunol.167.11.6330  0.319
2000 Lama J, Ware CF. Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells Journal of Virology. 74: 9396-9402. PMID 11000208 DOI: 10.1128/JVI.74.20.9396-9402.2000  0.347
2000 Elewaut D, Brossay L, Santee SM, Naidenko OV, Burdin N, De Winter H, Matsuda J, Ware CF, Cheroutre H, Kronenberg M. Membrane lymphotoxin is required for the development of different subpopulations of NK T cells. Journal of Immunology (Baltimore, Md. : 1950). 165: 671-9. PMID 10878339 DOI: 10.4049/Jimmunol.165.2.671  0.346
1998 Murphy M, Walter BN, Pike-Nobile L, Fanger NA, Guyre PM, Browning JL, Ware CF, Epstein LB. Expression of the lymphotoxin beta receptor on follicular stromal cells in human lymphoid tissues. Cell Death and Differentiation. 5: 497-505. PMID 10200501 DOI: 10.1038/Sj.Cdd.4400374  0.322
1997 Ortaldo JR, Winkler-Pickett RT, Nagata S, Ware CF. Fas involvement in human NK cell apoptosis: lack of a requirement for CD16-mediated events. Journal of Leukocyte Biology. 61: 209-15. PMID 9021927 DOI: 10.1002/jlb.61.2.209  0.353
1997 Brunner T, Yoo NJ, LaFace D, Ware CF, Green DR. Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506. International Immunology. 8: 1017-26. PMID 8757947 DOI: 10.1093/Intimm/8.7.1017  0.407
1995 Crowe PD, Walter BN, Mohler KM, Otten-Evans C, Black RA, Ware CF. A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. The Journal of Experimental Medicine. 181: 1205-10. PMID 7869036  0.372
1995 Mason AT, McVicar DW, Smith CA, Young HA, Ware CF, Ortaldo JR. Regulation of NK cells through the 80-kDa TNFR (CD120b). Journal of Leukocyte Biology. 58: 249-55. PMID 7543923 DOI: 10.1002/jlb.58.2.249  0.384
1995 Owen-Schaub LB, Angelo LS, Radinsky R, Ware CF, Gesner TG, Bartos DP. Soluble Fas/APO-1 in tumor cells: a potential regulator of apoptosis? Cancer Letters. 94: 1-8. PMID 7542559 DOI: 10.1016/0304-3835(95)03834-J  0.331
1995 Yang Y, Merćep M, Ware CF, Ashwell JD. Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids. The Journal of Experimental Medicine. 181: 1673-82. PMID 7536793 DOI: 10.1084/JEM.181.5.1673  0.446
1994 Crowe PD, VanArsdale TL, Walter BN, Dahms KM, Ware CF. Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system Journal of Immunological Methods. 168: 79-89. PMID 8288897 DOI: 10.1016/0022-1759(94)90212-7  0.381
1993 Crowe PD, VanArsdale TL, Goodwin RG, Ware CF. Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 151: 6882-90. PMID 8258697  0.339
1992 Androlewicz MJ, Browning JL, Ware CF. Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma. The Journal of Biological Chemistry. 267: 2542-7. PMID 1733951  0.681
1992 Ware CF, Crowe PD, Grayson MH, Androlewicz MJ, Browning JL. Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells. Journal of Immunology (Baltimore, Md. : 1950). 149: 3881-8. PMID 1281193  0.705
1991 Browning JL, Androlewicz MJ, Ware CF. Lymphotoxin and an associated 33-kDa glycoprotein are expressed on the surface of an activated human T cell hybridoma. Journal of Immunology (Baltimore, Md. : 1950). 147: 1230-7. PMID 1714477  0.713
1991 Ware CF, Crowe PD, Vanarsdale TL, Andrews JL, Grayson MH, Jerzy R, Smith CA, Goodwin RG. Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells. Journal of Immunology (Baltimore, Md. : 1950). 147: 4229-38. PMID 1661312  0.4
1990 LaCour EG, Grayson MH, Ware CF, Pope RM. Enhanced cytotoxicity in the rheumatoid joint. Clinical Immunology and Immunopathology. 54: 431-41. PMID 2302843 DOI: 10.1016/0090-1229(90)90056-V  0.362
1990 Andrews JS, Berger AE, Ware CF. Characterization of the receptor for tumor necrosis factor (TNF) and lymphotoxin (LT) on human T lymphocytes. TNF and LT differ in their receptor binding properties and the induction of MHC class I proteins on a human CD4+ T cell hybridoma. Journal of Immunology (Baltimore, Md. : 1950). 144: 2582-91. PMID 1969453  0.424
1989 Coffman FD, Haviland DL, Green LM, Ware CF. Cytotoxicity by tumor necrosis factor is linked with the cell cycle but does not require DNA synthesis Growth Factors. 1: 357-364. PMID 2634429 DOI: 10.3109/08977198909000259  0.321
1989 Coffman FD, Green LM, Godwin A, Ware CF. Cytotoxicity mediated by tumor necrosis factor in variant subclones of the ME-180 cervical carcinoma line: modulation by specific inhibitors of DNA topoisomerase II. Journal of Cellular Biochemistry. 39: 95-105. PMID 2541144 DOI: 10.1002/jcb.240390202  0.34
1988 Rodgers KE, Grayson MH, Ware CF. Inhibition of cytotoxic T lymphocyte and natural killer cell-mediated lysis by O,S,S,-trimethyl phosphorodithioate is at an early postrecognition step. Journal of Immunology (Baltimore, Md. : 1950). 140: 564-70. PMID 3257244  0.351
1986 Yamamoto RS, Ware CF, Granger GA. The human LT system. XI. Identification of LT and "TNF-like" forms from stimulated natural killers, specific and nonspecific cytotoxic human T cells in vitro. Journal of Immunology (Baltimore, Md. : 1950). 137: 1878-84. PMID 2943806  0.665
1985 Ware CF, Reade JL. Functional interactions of LFA-1, T8 and alloantigen surface structures in T-cell mediated cytotoxicity Advances in Experimental Medicine and Biology. 184: 323-341. PMID 2412414 DOI: 10.1007/978-1-4684-8326-0_22  0.318
1984 Green LM, Reade JL, Ware CF. Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines. Journal of Immunological Methods. 70: 257-68. PMID 6609997 DOI: 10.1016/0022-1759(84)90190-X  0.389
1984 Ware CF, Reade JL, Der LC. A rat anti-mouse kappa chain specific monoclonal antibody, 187.1.10: purification, immunochemical properties and its utility as a general second-antibody reagent. Journal of Immunological Methods. 74: 93-104. PMID 6438237 DOI: 10.1016/0022-1759(84)90371-5  0.322
1982 Sanchez-Madrid F, Krensky AM, Ware CF, Robbins E, Strominger JL, Burakoff SJ, Springer TA. Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proceedings of the National Academy of Sciences of the United States of America. 79: 7489-93. PMID 6984191 DOI: 10.1073/Pnas.79.23.7489  0.418
1982 Lawlor DA, Saunders PH, Ware CF. Rat antisera directed against alloimmune murine cytotoxic T lymphocytes inhibit cytotoxic T-lymphocyte and natural killer activity: strain specificity of inhibition. Cellular Immunology. 68: 128-38. PMID 6979399 DOI: 10.1016/0008-8749(82)90095-8  0.309
1981 Ware CF, Chauvenet PH, Duffey PS, Granger GA. Inhibition of the lytic phase of murine t-cell-mediated alloimmune cytotoxicity by a rat antiactivated t-cell antiserum. Cellular Immunology. 59: 289-300. PMID 6974600 DOI: 10.1016/0008-8749(81)90410-X  0.681
1981 Ware CF, Granger GA. Mechanisms of lymphocyte-mediated cytotoxicity. III. Characterization of the mechanism of inhibition of the human alloimmune lymphocyte-mediated cytotoxic reaction by polyspecific anti-lymphotoxin sera in vitro. Journal of Immunology (Baltimore, Md. : 1950). 126: 1934-40. PMID 6971314  0.597
1981 Ware CF, Granger GA. Mechanisms of lymphocyte-mediated cytotoxicity. I. The effects of anti-human lymphotoxin antisera on the cytolysis of allogeneic B cell lines by MLC-sensitized human lymphocytes in vitro Journal of Immunology. 126: 1919-1926. PMID 6452481  0.676
1981 Ware CF, Harris PC, Granger GA. Mechanisms of lymphocyte-mediated cytotoxicity. II. Biochemical and serologic identification of a precursor lymphotoxin form (pre-LT) produced by MLC-sensitized human T lymphocytes in vitro Journal of Immunology. 126: 1927-1933. PMID 6163823  0.683
1979 Ware CF, Granger GA. A physicochemical and immunologic comparison of the cell growth inhibitory activity of human lymphotoxins and interferons in vitro. Journal of Immunology (Baltimore, Md. : 1950). 122: 1763-70. PMID 312850  0.609
1977 Hiserodt JC, Ware CF, Harris PC, Granger GA. Identification of membrane-associated lymphotoxin (LT) on mitogen-activated human lymphocytes using heterologous anti-LT antisera in vitro Cellular Immunology. 34: 326-339. PMID 303942 DOI: 10.1016/0008-8749(77)90255-6  0.699
1977 Hiserodt JC, Ware CF, Granger GA. Identification Of Lymfhotoxin (Lt) As The Mediator Of Direct Cytolys Is Of L-929 Cells By Mitogen Activated Human Lymphocytes In Vitro Regulatory Mechanisms in Lymphocyte Activation. 551-553. DOI: 10.1016/B978-0-12-458050-3.50089-8  0.683
1976 Fair D, Jeffes E, Ware C, Granger G. The PGLC-33H cell line appears to secrete only a-Lymphotoxin Cellular Immunology. 27: 355. DOI: 10.1016/0008-8749(76)90308-7  0.536
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