Christian C. Felder - Publications

University of Maryland Dental School, Baltimore, MD, United States 

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Montani C, Canella C, Schwarz AJ, Li J, Gilmour G, Galbusera A, Wafford K, Gutierrez-Barragan D, McCarthy A, Shaw D, Knitowski K, McKinzie D, Gozzi A, Felder C. The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33342996 DOI: 10.1038/s41386-020-00916-0  1
2019 Coussens NP, Sittampalam GS, Jonson SG, Hall MD, Gorby HE, Tamiz AP, McManus OB, Felder CC, Rasmussen K. The Opioid Crisis and the Future of Addiction and Pain Therapeutics. The Journal of Pharmacology and Experimental Therapeutics. PMID 31481516 DOI: 10.1124/Jpet.119.259408  0.01
2019 Felder CC. GPCR drug discovery-moving beyond the orthosteric to the allosteric domain. Advances in Pharmacology (San Diego, Calif.). 86: 1-20. PMID 31378249 DOI: 10.1016/bs.apha.2019.04.002  0.01
2019 Hollingsworth SA, Kelly B, Valant C, Michaelis JA, Mastromihalis O, Thompson G, Venkatakrishnan AJ, Hertig S, Scammells PJ, Sexton PM, Felder CC, Christopoulos A, Dror RO. Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs. Nature Communications. 10: 3289. PMID 31337749 DOI: 10.1038/s41467-019-11062-7  1
2019 Knopp KL, Simmons RMA, Guo W, Adams BL, Gardinier KM, Gernert DL, Ornstein PL, Porter W, Reel J, Ding C, Wang H, Qian Y, Burris KD, Need A, Barth V, ... ... Felder CC, et al. Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 30910921 DOI: 10.1124/Jpet.118.250126  1
2019 Liu X, Thomas CE, Felder CC. The innovation ecosystem: an analysis of a decade of approved and failed drugs. International Journal of Pharmaceutics. PMID 30664998 DOI: 10.1016/j.ijpharm.2018.12.093  0.01
2018 Broad LM, Sanger HE, Mogg AJ, Colvin EM, Zwart R, Evans DA, Pasqui F, Sher E, Wishart GN, Barth VN, Felder CC, Goldsmith PJ. Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant M1 muscarinic acetylcholine receptor agonist. British Journal of Pharmacology. PMID 30276808 DOI: 10.1111/Bph.14510  1
2018 Bradley SJ, Molloy C, Bundgaard C, Mogg AJ, Thompson KJ, Dwomoh L, Sanger HE, Crabtree M, Brooke SM, Sexton PM, Felder CC, Christopoulos A, Broad LM, Tobin AB, Langmead CJ. Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes. Molecular Pharmacology. PMID 29695609 DOI: 10.1124/Mol.118.111872  1
2018 Mogg AJ, Eessalu T, Johnson M, Wright R, Sanger HE, Xiou H, Crabtree M, Smith A, Colvin E, Schober D, Gehlert D, Jesudason C, Goldsmith P, Johnson MP, Felder CC, et al. pharmacological characterization and validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography (PET). The Journal of Pharmacology and Experimental Therapeutics. PMID 29643252 DOI: 10.1124/Jpet.117.246454  1
2018 Felder CC, Goldsmith PJ, Jackson K, Sanger HE, Evans DA, Mogg AJ, Broad LM. Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases. Neuropharmacology. PMID 29374561 DOI: 10.1016/J.Neuropharm.2018.01.028  1
2017 Schober DA, Croy CH, Ruble CL, Tao R, Felder CC. Identification, expression and functional characterization of M4L, a muscarinic acetylcholine M4 receptor splice variant. Plos One. 12: e0188330. PMID 29211764 DOI: 10.1371/Journal.Pone.0188330  1
2017 Udawela M, Scarr E, Boer S, Um JY, Hannan AJ, McOmish C, Felder CC, Thomas EA, Dean B. Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide. Npj Schizophrenia. 3: 19. PMID 28560265 DOI: 10.1038/s41537-017-0020-x  1
2017 Martin AE, Schober DA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Laksmanan A, Catlow JT, Li X, Felder CC, Witkin JM. Further evaluation of mechanisms associated with the antidepressant-like signature of scopolamine in mice. Cns & Neurological Disorders Drug Targets. PMID 28294051 DOI: 10.2174/1871527316666170309142646  1
2017 Felder CC, Schober DA, Tu Y, Quets AT, Xiao H, Watt M, Siuda ER, Nisenbaum ES, Xiang C, Heinz B, Prieto L, Mc Kinzie DL, Monn JA. Translational pharmacology of the mGluR2-preferring agonist LY2812223 in animal and human brain. The Journal of Pharmacology and Experimental Therapeutics. PMID 28138041 DOI: 10.1124/Jpet.116.237859  1
2017 Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE. Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrobial Agents and Chemotherapy. PMID 28137807 DOI: 10.1128/Aac.01938-16  0.01
2016 Bradley SJ, Bourgognon JM, Sanger HE, Verity N, Mogg AJ, White DJ, Butcher AJ, Moreno JA, Molloy C, Macedo-Hatch T, Edwards JM, Wess J, Pawlak R, Read DJ, Sexton PM, ... ... Felder CC, et al. M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss. The Journal of Clinical Investigation. PMID 27991860 DOI: 10.1172/Jci87526  1
2016 Croy CH, Chan WY, Castetter AM, Watt ML, Quets AT, Felder CC. Characterization of PCS1055, a Novel Muscarinic M4 Receptor Antagonist. European Journal of Pharmacology. PMID 27085897 DOI: 10.1016/J.Ejphar.2016.04.022  1
2016 Dym O, Song W, Felder C, Roth E, Shnyrov V, Ashani Y, Xu Y, Joosten RP, Weiner L, Sussman JL, Silman I. The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue/Acetylcholinesterase Complex. Protein Science : a Publication of the Protein Society. PMID 26990888 DOI: 10.1002/Pro.2923  1
2016 Thal DM, Sun B, Feng D, Nawaratne V, Leach K, Felder CC, Bures MG, Evans DA, Weis WI, Bachhawat P, Kobilka TS, Sexton PM, Kobilka BK, Christopoulos A. Crystal structures of the M1 and M4 muscarinic acetylcholine receptors. Nature. PMID 26958838 DOI: 10.1038/Nature17188  1
2016 Butcher AJ, Bradley SJ, Prihandoko R, Brooke SM, Mogg A, Bourgognon JM, Macedo-Hatch T, Edwards JM, Bottrill AR, Challiss RA, Broad LM, Felder CC, Tobin AB. An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory. The Journal of Biological Chemistry. 291: 8862-75. PMID 26826123 DOI: 10.1074/Jbc.M115.681726  1
2015 Dennis SH, Pasqui F, Colvin EM, Sanger H, Mogg AJ, Felder CC, Broad LM, Fitzjohn SM, Isaac JT, Mellor JR. Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). PMID 26472558 DOI: 10.1093/Cercor/Bhv227  1
2015 Liu B, Croy CH, Hitchcock SA, Allen JR, Rao Z, Evans D, Bures MG, McKinzie DL, Watt ML, Stuart Gregory G, Hansen MM, Hoogestraat PJ, Jamison JA, Okha-Mokube FM, Stratford RE, ... ... Felder CC, et al. Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists. Bioorganic & Medicinal Chemistry Letters. PMID 26299349 DOI: 10.1016/J.Bmcl.2015.08.011  1
2015 Andersen MB, Croy CH, Dencker D, Werge T, Bymaster FP, Felder CC, Fink-Jensen A. Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates. Plos One. 10: e0122722. PMID 25880220 DOI: 10.1371/Journal.Pone.0122722  1
2015 Bakker G, Vingerhoets WA, van Wieringen JP, de Bruin K, Eersels J, de Jong J, Chahid Y, Rutten BP, DuBois S, Watson M, Mogg AJ, Xiao H, Crabtree M, Collier DA, Felder CC, et al. 123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 56: 317-22. PMID 25593117 DOI: 10.2967/Jnumed.114.147488  1
2015 Gitschier HJ, Bergeron AB, Randle DH, Bacon CE, Baez M, Yang P, Broad LM, Goldsmith PJ, Felder CC, Schober DA. Triple-addition label-free assays for high-throughput screening of muscarinic M1 receptor agonists, antagonists, and allosteric modulators Label-Free Biosensor Methods in Drug Discovery. 197-214. DOI: 10.1007/978-1-4939-2617-6_11  1
2014 Witkin JM, Overshiner C, Li X, Catlow JT, Wishart GN, Schober DA, Heinz BA, Nikolayev A, Tolstikov VV, Anderson WH, Higgs RE, Kuo MS, Felder CC. M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine. The Journal of Pharmacology and Experimental Therapeutics. 351: 448-56. PMID 25187432 DOI: 10.1124/Jpet.114.216804  1
2014 Schober DA, Croy CH, Xiao H, Christopoulos A, Felder CC. Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites. Molecular Pharmacology. 86: 116-23. PMID 24807966 DOI: 10.1124/Mol.114.091785  1
2014 Croy CH, Schober DA, Xiao H, Quets A, Christopoulos A, Felder CC. Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors. Molecular Pharmacology. 86: 106-15. PMID 24807965 DOI: 10.1124/Mol.114.091751  1
2014 Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons. Psychopharmacology. 231: 1105-24. PMID 24429870 DOI: 10.1007/S00213-013-3384-2  1
2013 Kruse AC, Ring AM, Manglik A, Hu J, Hu K, Eitel K, Hübner H, Pardon E, Valant C, Sexton PM, Christopoulos A, Felder CC, Gmeiner P, Steyaert J, Weis WI, et al. Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature. 504: 101-6. PMID 24256733 DOI: 10.1038/Nature12735  1
2013 Watt ML, Rorick-Kehn L, Shaw DB, Knitowski KM, Quets AT, Chesterfield AK, McKinzie DL, Felder CC. The muscarinic acetylcholine receptor agonist BuTAC mediates antipsychotic-like effects via the M4 subtype. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2717-26. PMID 23907402 DOI: 10.1038/Npp.2013.186  1
2013 Gibbons AS, Scarr E, Boer S, Money T, Jeon WJ, Felder C, Dean B. Widespread decreases in cortical muscarinic receptors in a subset of people with schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 37-46. PMID 22338582 DOI: 10.1017/S1461145712000028  1
2012 Valant C, Felder CC, Sexton PM, Christopoulos A. Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects. Molecular Pharmacology. 81: 41-52. PMID 21989256 DOI: 10.1124/Mol.111.074872  1
2012 Felder CC, McKinzie DL, Thompson RC, Liu B. Muscarinic Acetylcholine Receptors as Novel Targets for the Development of Therapeutics for Schizophrenia Targets and Emerging Therapies For Schizophrenia. 355-379. DOI: 10.1002/9781118309421.ch13  1
2011 Watt ML, Schober DA, Hitchcock S, Liu B, Chesterfield AK, McKinzie D, Felder CC. Pharmacological characterization of LY593093, an M1 muscarinic acetylcholine receptor-selective partial orthosteric agonist. The Journal of Pharmacology and Experimental Therapeutics. 338: 622-32. PMID 21558436 DOI: 10.1124/Jpet.111.182063  1
2011 Schober DA, Gill MB, Yu H, Gernert DL, Jeffries MW, Ornstein PL, Kato AS, Felder CC, Bredt DS. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of Biological Chemistry. 286: 13134-42. PMID 21343286 DOI: 10.1074/Jbc.M110.212522  1
2011 Leach K, Davey AE, Felder CC, Sexton PM, Christopoulos A. The role of transmembrane domain 3 in the actions of orthosteric, allosteric, and atypical agonists of the M4 muscarinic acetylcholine receptor. Molecular Pharmacology. 79: 855-65. PMID 21300722 DOI: 10.1124/Mol.111.070938  1
2011 Suratman S, Leach K, Sexton P, Felder C, Loiacono R, Christopoulos A. Impact of species variability and 'probe-dependence' on the detection and in vivo validation of allosteric modulation at the M4 muscarinic acetylcholine receptor. British Journal of Pharmacology. 162: 1659-70. PMID 21198541 DOI: 10.1111/J.1476-5381.2010.01184.X  1
2011 Fell MJ, Witkin JM, Falcone JF, Katner JS, Perry KW, Hart J, Rorick-Kehn L, Overshiner CD, Rasmussen K, Chaney SF, Benvenga MJ, Li X, Marlow DL, Thompson LK, Luecke SK, ... ... Felder CC, et al. N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes. The Journal of Pharmacology and Experimental Therapeutics. 336: 165-77. PMID 20947638 DOI: 10.1124/Jpet.110.172957  1
2010 Suter TM, Chesterfield AK, Bao C, Schaus JM, Krushinski JH, Statnick MA, Felder CC. Pharmacological characterization of the cannabinoid CB₁ receptor PET ligand ortholog, [³H]MePPEP. European Journal of Pharmacology. 649: 44-50. PMID 20851117 DOI: 10.1016/J.Ejphar.2010.08.055  1
2010 Nawaratne V, Leach K, Felder CC, Sexton PM, Christopoulos A. Structural determinants of allosteric agonism and modulation at the M4 muscarinic acetylcholine receptor: identification of ligand-specific and global activation mechanisms. The Journal of Biological Chemistry. 285: 19012-21. PMID 20406819 DOI: 10.1074/Jbc.M110.125096  1
2010 Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ. Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease. Journal of Chemical Neuroanatomy. 40: 63-70. PMID 20347961 DOI: 10.1016/J.Jchemneu.2010.03.005  1
2010 Terry GE, Hirvonen J, Liow JS, Seneca N, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Pike VW, Halldin C, Innis RB. Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1499-506. PMID 20333514 DOI: 10.1007/S00259-010-1411-7  1
2010 Terry GE, Hirvonen J, Liow JS, Zoghbi SS, Gladding R, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Donohue SR, Pike VW, Halldin C, Innis RB. Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 112-20. PMID 20008988 DOI: 10.2967/Jnumed.109.067074  1
2010 Leach K, Loiacono RE, Felder CC, McKinzie DL, Mogg A, Shaw DB, Sexton PM, Christopoulos A. Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 855-69. PMID 19940843 DOI: 10.1038/Npp.2009.194  1
2009 Terry GE, Liow JS, Zoghbi SS, Hirvonen J, Farris AG, Lerner A, Tauscher JT, Schaus JM, Phebus L, Felder CC, Morse CL, Hong JS, Pike VW, Halldin C, Innis RB. Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand. Neuroimage. 48: 362-70. PMID 19573609 DOI: 10.1016/J.Neuroimage.2009.06.059  1
2009 Shekhar A, McKinzie DL, Felder CC. Drs. Shekhar, McKinzie, and Felder reply American Journal of Psychiatry. 166: 113. DOI: 10.1176/Appi.Ajp.2008.08091352R1  1
2008 Donohue SR, Krushinski JH, Pike VW, Chernet E, Phebus L, Chesterfield AK, Felder CC, Halldin C, Schaus JM. Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging. Journal of Medicinal Chemistry. 51: 5833-42. PMID 18800770 DOI: 10.1021/Jm800416M  1
2008 Chan WY, McKinzie DL, Bose S, Mitchell SN, Witkin JM, Thompson RC, Christopoulos A, Lazareno S, Birdsall NJ, Bymaster FP, Felder CC. Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 105: 10978-83. PMID 18678919 DOI: 10.1073/Pnas.0800567105  1
2008 Nawaratne V, Leach K, Suratman N, Loiacono RE, Felder CC, Armbruster BN, Roth BL, Sexton PM, Christopoulos A. New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug). Molecular Pharmacology. 74: 1119-31. PMID 18628403 DOI: 10.1124/Mol.108.049353  1
2008 Shekhar A, Potter WZ, Lightfoot J, Lienemann J, Dubé S, Mallinckrodt C, Bymaster FP, McKinzie DL, Felder CC. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. The American Journal of Psychiatry. 165: 1033-9. PMID 18593778 DOI: 10.1176/Appi.Ajp.2008.06091591  1
2008 Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3024-34. PMID 18492727 DOI: 10.1096/Fj.07-101865  1
2008 Terry G, Liow JS, Chernet E, Zoghbi SS, Phebus L, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. Neuroimage. 41: 690-8. PMID 18456516 DOI: 10.1016/J.Neuroimage.2008.03.004  1
2008 Yasuno F, Brown AK, Zoghbi SS, Krushinski JH, Chernet E, Tauscher J, Schaus JM, Phebus LA, Chesterfield AK, Felder CC, Gladding RL, Hong J, Halldin C, Pike VW, Innis RB. The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 259-69. PMID 17392732 DOI: 10.1038/Sj.Npp.1301402  1
2008 Terry GE, Liow J-, Chernet E, Zoghbi SS, Phebus L, Lerner A, Felder CC, Tauscher J, Schaus JM, Pike VW, Halldin C, Innis RB. Evaluation of an inverse agonist with high affinity for the CB1 receptor, [11C]MePPEP, in rodents and humans Neuroimage. 41. DOI: 10.1016/J.Neuroimage.2008.04.164  1
2007 Felder CE, Prilusky J, Silman I, Sussman JL. A server and database for dipole moments of proteins. Nucleic Acids Research. 35: W512-21. PMID 17526523 DOI: 10.1093/Nar/Gkm307  0.01
2007 Margulies D, Felder CE, Melman G, Shanzer A. A molecular keypad lock: a photochemical device capable of authorizing password entries. Journal of the American Chemical Society. 129: 347-54. PMID 17212414 DOI: 10.1021/Ja065317Z  1
2006 Albeck S, Alzari P, Andreini C, Banci L, Berry IM, Bertini I, Cambillau C, Canard B, Carter L, Cohen SX, Diprose JM, Dym O, Esnouf RM, Felder C, Ferron F, et al. SPINE bioinformatics and data-management aspects of high-throughput structural biology. Acta Crystallographica. Section D, Biological Crystallography. 62: 1184-95. PMID 17001095 DOI: 10.1107/S090744490602991X  1
2006 Felder CC, Dickason-Chesterfield AK, Moore SA. Cannabinoids biology: the search for new therapeutic targets. Molecular Interventions. 6: 149-61. PMID 16809476 DOI: 10.1124/Mi.6.3.6  1
2006 Dickason-Chesterfield AK, Kidd SR, Moore SA, Schaus JM, Liu B, Nomikos GG, Felder CC. Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. Cellular and Molecular Neurobiology. 26: 407-23. PMID 16736384 DOI: 10.1007/S10571-006-9072-6  1
2006 Felder CC. Endocannabinoids and their receptors as targets for treating metabolic and psychiatric disorders Drug Discovery Today: Therapeutic Strategies. 3: 561-567. DOI: 10.1016/J.Ddstr.2006.10.015  0.01
2005 Kahl SD, Felder CC. Scintillation proximity assay. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 7.15. PMID 18428624 DOI: 10.1002/0471142301.ns0715s30  0.01
2005 Moore SA, Nomikos GG, Dickason-Chesterfield AK, Schober DA, Schaus JM, Ying BP, Xu YC, Phebus L, Simmons RM, Li D, Iyengar S, Felder CC. Identification of a high-affinity binding site involved in the transport of endocannabinoids. Proceedings of the National Academy of Sciences of the United States of America. 102: 17852-7. PMID 16314570 DOI: 10.1073/Pnas.0507470102  1
2005 Bazinet RP, Lee HJ, Felder CC, Porter AC, Rapoport SI, Rosenberger TA. Rapid high-energy microwave fixation is required to determine the anandamide (N-arachidonoylethanolamine) concentration of rat brain. Neurochemical Research. 30: 597-601. PMID 16176062 DOI: 10.1007/S11064-005-2746-5  1
2005 Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, Beckmann JS, Silman I, Sussman JL. FoldIndex©: A simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics. 21: 3435-3438. PMID 15955783 DOI: 10.1093/Bioinformatics/Bti537  1
2004 Margulies D, Melman G, Felder CE, Arad-Yellin R, Shanzer A. Chemical input multiplicity facilitates arithmetical processing. Journal of the American Chemical Society. 126: 15400-1. PMID 15563165 DOI: 10.1021/Ja0453329  1
2004 Felder CC. Strategic Research Institute G-Protein-Coupled Receptors Drug Discovery World Summit. Expert Opinion On Investigational Drugs. 13: 1071-4. PMID 15268643 DOI: 10.1517/13543784.13.8.1071  0.01
2004 Tzavara ET, Bymaster FP, Davis RJ, Wade MR, Perry KW, Wess J, McKinzie DL, Felder C, Nomikos GG. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1410-2. PMID 15231726 DOI: 10.1096/Fj.04-1575Fje  1
2004 Pe'er I, Felder CE, Man O, Silman I, Sussman JL, Beckmann JS. Proteomic signatures: amino acid and oligopeptide compositions differentiate among phyla. Proteins. 54: 20-40. PMID 14705021 DOI: 10.1002/Prot.10559  1
2003 Bymaster FP, Felder CC, Tzavara E, Nomikos GG, Calligaro DO, Mckinzie DL. Muscarinic mechanisms of antipsychotic atypicality. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 1125-43. PMID 14642972 DOI: 10.1016/J.Pnpbp.2003.09.008  1
2003 Eap CB, Felder C, Golay KP, Uehlinger C. Increase of oral methadone dose in methadone injecting patients: a pilot study. Journal of Addictive Diseases. 22: 7-17. PMID 14621341 DOI: 10.1300/J069v22n03_02  0.01
2003 Felder ChB, Blanco-Príeto MJ, Heizmann J, Merkle HP, Gander B. Ultrasonic atomization and subsequent polymer desolvation for peptide and protein microencapsulation into biodegradable polyesters. Journal of Microencapsulation. 20: 553-67. PMID 12909541 DOI: 10.1080/0265204031000148059  0.01
2003 Wess J, Duttaroy A, Zhang W, Gomeza J, Cui Y, Miyakawa T, Bymaster FP, McKinzie L, Felder CC, Lamping KG, Faraci FM, Deng C, Yamada M. M1-M5 muscarinic receptor knockout mice as novel tools to study the physiological roles of the muscarinic cholinergic system. Receptors & Channels. 9: 279-90. PMID 12893539 DOI: 10.1080/10606820308262  1
2003 Tzavara ET, Bymaster FP, Felder CC, Wade M, Gomeza J, Wess J, McKinzie DL, Nomikos GG. Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice. Molecular Psychiatry. 8: 673-9. PMID 12874603 DOI: 10.1038/  1
2003 Wang GJ, Volkow ND, Fowler JS, Franceschi D, Wong CT, Pappas NR, Netusil N, Zhu W, Felder C, Ma Y. Alcohol intoxication induces greater reductions in brain metabolism in male than in female subjects. Alcoholism, Clinical and Experimental Research. 27: 909-17. PMID 12824811 DOI: 10.1111/J.1530-0277.2003.Tb04415.X  1
2003 Felder CR. To buy or not to buy. Rehab Management. 16: 26-8. PMID 12741234  0.01
2003 Bymaster FP, Carter PA, Yamada M, Gomeza J, Wess J, Hamilton SE, Nathanson NM, McKinzie DL, Felder CC. Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. The European Journal of Neuroscience. 17: 1403-10. PMID 12713643 DOI: 10.1046/J.1460-9568.2003.02588.X  1
2003 Bymaster FP, McKinzie DL, Felder CC, Wess J. Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system. Neurochemical Research. 28: 437-42. PMID 12675128 DOI: 10.1023/A:1022844517200  1
2003 Wess J, Duttaroy A, Gomeza J, Zhang W, Yamada M, Felder CC, Bernardini N, Reeh PW. Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: A review Life Sciences. 72: 2047-2054. PMID 12628455 DOI: 10.1016/S0024-3205(03)00082-1  1
2003 Felder CE, Shanzer A. Application of the empirical force field to macrocyclic ion carriers, siderophores, and biomimetic analogs. Biopolymers. 68: 407-21. PMID 12601799 DOI: 10.1002/Bip.10288  1
2002 Bymaster FP, Felder C, Ahmed S, McKinzie D. Muscarinic receptors as a target for drugs treating schizophrenia. Current Drug Targets. Cns and Neurological Disorders. 1: 163-81. PMID 12769625 DOI: 10.2174/1568007024606249  1
2002 Logan J, Fowler JS, Ding YS, Franceschi D, Wang GJ, Volkow ND, Felder C, Alexoff D. Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase A tracers [11C]clorgyline and deuterium-substituted [11C]clorgyline. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1367-76. PMID 12439294 DOI: 10.1097/01.Wcb.0000040947.67415.E1  0.01
2002 Duttaroy A, Gomeza J, Gan JW, Siddiqui N, Basile AS, Harman WD, Smith PL, Felder CC, Levey AI, Wess J. Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice. Molecular Pharmacology. 62: 1084-93. PMID 12391271 DOI: 10.1124/Mol.62.5.1084  1
2002 Ashkenasy G, Margulies D, Felder CE, Shanzer A, Powers LS. Bidentate ligation of heme analogues; novel biomimetics of peroxidase active site. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 4017-26. PMID 12360943 DOI: 10.1002/1521-3765(20020902)8:17<4017::Aid-Chem4017>3.0.Co;2-S  1
2002 Felder CE, Harel M, Silman I, Sussman JL. Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase. Acta Crystallographica. Section D, Biological Crystallography. 58: 1765-71. PMID 12351819 DOI: 10.1107/S0907444902011642  1
2002 Hemrick-Luecke SK, Bymaster FP, Evans DC, Wess J, Felder CC. Muscarinic agonist-mediated increases in serum corticosterone levels are abolished in m(2) muscarinic acetylcholine receptor knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 99-103. PMID 12235238 DOI: 10.1124/Jpet.102.036020  1
2002 Wang GJ, Volkow ND, Felder C, Fowler JS, Levy AV, Pappas NR, Wong CT, Zhu W, Netusil N. Enhanced resting activity of the oral somatosensory cortex in obese subjects. Neuroreport. 13: 1151-5. PMID 12151759 DOI: 10.1097/00001756-200207020-00016  1
2002 Porter AC, Bymaster FP, DeLapp NW, Yamada M, Wess J, Hamilton SE, Nathanson NM, Felder CC. M1 muscarinic receptor signaling in mouse hippocampus and cortex. Brain Research. 944: 82-9. PMID 12106668 DOI: 10.1016/S0006-8993(02)02721-X  1
2002 Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161  1
2002 Porter AC, Sauer JM, Knierman MD, Becker GW, Berna MJ, Bao J, Nomikos GG, Carter P, Bymaster FP, Leese AB, Felder CC. Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor Journal of Pharmacology and Experimental Therapeutics. 301: 1020-1024. PMID 12023533 DOI: 10.1124/Jpet.301.3.1020  1
2002 Bymaster FP, Felder CC. Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents. Molecular Psychiatry. 7: S57-63. PMID 11986996 DOI: 10.1038/  1
2002 Volkow ND, Zhu W, Felder CA, Mueller K, Welsh TF, Wang GJ, de Leon MJ. Changes in brain functional homogeneity in subjects with Alzheimer's disease. Psychiatry Research. 114: 39-50. PMID 11864808 DOI: 10.1016/S0925-4927(01)00130-5  0.01
2002 Lin P, Kusano K, Zhang Q, Felder CC, Geiger PM, Mahan LC. GABAA Receptors Modulate Early Spontaneous Excitatory Activity in Differentiating P19 Neurons Journal of Neurochemistry. 66: 233-242. PMID 8522959 DOI: 10.1046/J.1471-4159.1996.66010233.X  1
2002 Gomeza J, Yamada M, Duttaroy A, Zhang W, Makita R, Miyakawa T, Crawley J, Zhang L, Shannon H, Bymaster FP, Felder CC, Deng C, Wess J. Muscarinic acetylcholine receptor knockout mice: Phenotypical analysis and clinical implications Pharmacochemistry Library. 32: 97-113. DOI: 10.1016/S0165-7208(02)80012-5  1
2001 Kennedy JS, Bymaster FP, Schuh L, Calligaro DO, Nomikos G, Felder CC, Bernauer M, Kinon BJ, Baker RW, Hay D, Roth HJ, Dossenbach M, Kaiser C, Beasley CM, Holcombe JH, et al. A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data. International Journal of Geriatric Psychiatry. 16: S33-61. PMID 11748788 DOI: 10.1002/1099-1166(200112)16:1+<::Aid-Gps571>3.0.Co;2-5  1
2001 Fowler JS, Logan J, Ding YS, Franceschi D, Wang GJ, Volkow ND, Pappas N, Schlyer D, Gatley SJ, Alexoff D, Felder C, Biegon A, Zhu W. Non-MAO A binding of clorgyline in white matter in human brain. Journal of Neurochemistry. 79: 1039-46. PMID 11739617 DOI: 10.1046/J.1471-4159.2001.00649.X  0.01
2001 Stamer WD, Golightly SF, Hosohata Y, Ryan EP, Porter AC, Varga E, Noecker RJ, Felder CC, Yamamura HI. Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. European Journal of Pharmacology. 431: 277-86. PMID 11730719 DOI: 10.1016/S0014-2999(01)01438-8  1
2001 Yamada M, Lamping KG, Duttaroy A, Zhang W, Cui Y, Bymaster FP, McKinzie DL, Felder CC, Deng CX, Faraci FM, Wess J. Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 14096-101. PMID 11707605 DOI: 10.1073/Pnas.251542998  1
2001 Bymaster FP, Carter PA, DeLapp NW, Calligaro DO, Felder CC. Receptor reserve of phosphoinositide-coupled muscarinic receptors in mouse hippocampus in vivo Brain Research. 916: 165-171. PMID 11597604 DOI: 10.1016/S0006-8993(01)02889-X  1
2001 Porter AC, Felder CC. The endocannabinoid nervous system: Unique opportunities for therapeutic intervention Pharmacology and Therapeutics. 90: 45-60. PMID 11448725 DOI: 10.1016/S0163-7258(01)00130-9  1
2001 Felder CC, Porter AC, Skillman TL, Zhang L, Bymaster FP, Nathanson NM, Hamilton SE, Gomeza J, Wess J, McKinzie DL. Elucidating the role of muscarinic receptors in psychosis. Life Sciences. 68: 2605-13. PMID 11392633 DOI: 10.1016/S0024-3205(01)01059-1  1
2001 Salamone JD, Correa M, Carlson BB, Wisniecki A, Mayorga AJ, Nisenbaum E, Nisenbaum L, Felder C. Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents implications for cholinergic involvement in parkinsonism. Life Sciences. 68: 2579-84. PMID 11392629 DOI: 10.1016/S0024-3205(01)01055-4  1
2001 Bymaster FP, Carter PA, Zhang L, Falcone JF, Stengel PW, Cohen ML, Shannon HE, Gomeza J, Wess J, Felder CC. Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice. Life Sciences. 68: 2473-9. PMID 11392615 DOI: 10.1016/S0024-3205(01)01041-4  1
2001 Gomeza J, Zhang L, Kostenis E, Felder CC, Bymaster FP, Brodkin J, Shannon H, Xia B, Duttaroy A, Deng Cx, Wess J. Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice Life Sciences. 68: 2457-2466. PMID 11392613 DOI: 10.1016/S0024-3205(01)01039-6  1
2001 Perry KW, Nisenbaum LK, George CA, Shannon HE, Felder CC, Bymaster FP. The muscarinic agonist xanomeline increases monoamine release and immediate early gene expression in the rat prefrontal cortex. Biological Psychiatry. 49: 716-25. PMID 11313039 DOI: 10.1016/S0006-3223(00)01017-9  1
2001 Yamada M, Miyakawa T, Duttaroy A, Yamanaka A, Moriguchi T, Makita R, Ogawa M, Chou CJ, Xia B, Crawley JN, Felder CC, Deng CX, Wess J. Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean. Nature. 410: 207-12. PMID 11242080 DOI: 10.1038/35065604  1
2001 Kennedy JS, Tune LE, Calligaro D, Bymaster FP, Felder CC, Verma S. The muscarinic (hm1-m5) and neuronal-nicotinic receptors binding profile of some medicines reported to have serum anticholinergic activity European Neuropsychopharmacology. 11. DOI: 10.1016/S0924-977X(01)80533-2  1
2000 Felder CB, Vorlaender N, Gander B, Merkle HP, Bertschinger HU. Microencapsulated enterotoxigenic Escherichia coli and detached fimbriae for peroral vaccination of pigs. Vaccine. 19: 706-15. PMID 11115691 DOI: 10.1016/S0264-410X(00)00264-4  0.01
2000 Felder CC, Bymaster FP, Ward J, DeLapp N. Therapeutic opportunities for muscarinic receptors in the central nervous system. Journal of Medicinal Chemistry. 43: 4333-53. PMID 11087557 DOI: 10.1021/Jm990607U  1
2000 Volkow ND, Wang GJ, Fowler JS, Rooney WD, Felder CA, Lee JH, Franceschi D, Maynard L, Schlyer DJ, Pan JW, Gatley SJ, Springer Jr CS. Resting brain metabolic activity in a 4 tesla magnetic field. Magnetic Resonance in Medicine. 44: 701-5. PMID 11064404 DOI: 10.1002/1522-2594(200011)44:5<701::Aid-Mrm7>3.0.Co;2-J  1
2000 Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley JS, Pappas NR, Wong CT, Felder C. Increased activity of the temporal insula in subjects with bradycardia Life Sciences. 67: 2213-2220. PMID 11045602 DOI: 10.1016/S0024-3205(00)00807-9  1
2000 Appel R, Atoyan GS, Bassalleck B, Bergman DR, Brown DN, Cheung N, Dhawan S, Do H, Egger J, Eilerts S, Felder C, Fischer H, Gach M, Herold W, Issakov VV, et al. Improved limit on the rate of the decay K+ --> pi(+)&mgr;(+)e(-) Physical Review Letters. 85: 2450-3. PMID 10978079 DOI: 10.1103/Physrevlett.85.2450  0.01
2000 Wang GJ, Volkow ND, Franceschi D, Fowler JS, Thanos PK, Scherbaum N, Pappas N, Wong CT, Hitzemann RJ, Felder CA. Regional brain metabolism during alcohol intoxication. Alcoholism, Clinical and Experimental Research. 24: 822-9. PMID 10888070  1
2000 Buckley NE, McCoy KL, Mezey E, Bonner T, Zimmer A, Felder CC, Glass M, Zimmer A. Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. European Journal of Pharmacology. 396: 141-9. PMID 10822068 DOI: 10.1016/S0014-2999(00)00211-9  1
2000 Wood MW, Segal JA, Mark RJ, Ogden AM, Felder CC. Inflammatory cytokines enhance muscarinic-mediated arachidonic acid release through p38 mitogen-activated protein kinase in A2058 cells. Journal of Neurochemistry. 74: 2033-40. PMID 10800946 DOI: 10.1046/j.1471-4159.2000.0742033.x  1
1999 Fowler JS, Volkow ND, Cilento R, Wang GJ, Felder C, Logan J. Comparison of Brain Glucose Metabolism and Monoamine Oxidase B (MAO B) in Traumatic Brain Injury. Clinical Positron Imaging : Official Journal of the Institute For Clinical P.E.T. 2: 71-79. PMID 14516543 DOI: 10.1016/S1095-0397(99)00010-2  0.01
1999 Felder CB, Graul RC, Lee AY, Merkle HP, Sadee W. The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors. Aaps Pharmsci. 1: E2. PMID 11741199  0.01
1999 Jeppesen L, Olesen PH, Hansen L, Sheardown MJ, Thomsen C, Rasmussen T, Jensen AF, Christensen MS, Rimvall K, Ward JS, Whitesitt C, Calligaro DO, Bymaster FP, Delapp NW, Felder CC, et al. 1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives. Journal of Medicinal Chemistry. 42: 1999-2006. PMID 10354408 DOI: 10.1021/Jm9910019  1
1999 Yang HY, Karoum F, Felder C, Badger H, Wang TC, Markey SP. GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat. Journal of Neurochemistry. 72: 1959-68. PMID 10217273 DOI: 10.1046/J.1471-4159.1999.0721959.X  1
1999 McKinzie JH, Sawyer BD, Felder CC, Falcone J, Silbernagel A, McClure D, DeLapp NW. An anti-G protein scintillation proximity assay for M1–M5 receptor-mediated GTPγS binding Life Sciences. 64: 570. DOI: 10.1016/S0024-3205(99)90495-2  1
1999 DeLapp NW, McClure D, McKinzie J, Silbernagel A, Sawyer BD, Felder CC. A study of M1 receptor coupling to inhibitory G proteins in CHO cells via GTPγS binding determined with anti-G protein antibodies Life Sciences. 64: 569. DOI: 10.1016/S0024-3205(99)90494-0  1
1999 Sawyer BD, Silbernagel A, McKinzie JB, Falcone J, Delapp N, Felder CC. Comparison of GTP-γ-35S and 3H-NMS binding in CHO cells stably expressing human M1–M5 muscarinic receptors using scintillation proximity assays Life Sciences. 64: 568. DOI: 10.1016/S0024-3205(99)90492-7  0.01
1999 Wood MW, Briley EM, Felder CC. Muscarinic receptor-activated arachidonic acid release is enhanced by cytokines in A2058 human melanoma cells Life Sciences. 64: 566. DOI: 10.1016/S0024-3205(99)90487-3  1
1998 Lautens LL, Chiou XG, Sharp JD, Young WS, Sprague DL, Ross LS, Felder CC. Cytosolic phospholipase A2 (cPLA2) distribution in murine brain and functional studies indicate that cPLA2 does not participate in muscarinic receptor-mediated signaling in neurons. Brain Research. 809: 18-30. PMID 9795110 DOI: 10.1016/S0006-8993(98)00806-3  1
1998 Felder CC, Glass M. Cannabinoid receptors and their endogenous agonists. Annual Review of Pharmacology and Toxicology. 38: 179-200. PMID 9597153 DOI: 10.1146/Annurev.Pharmtox.38.1.179  1
1998 Axelrod J, Felder CC. Cannabinoid receptors and their endogenous agonist, anandamide. Neurochemical Research. 23: 575-81. PMID 9566594 DOI: 10.1023/A:1022418217479  1
1998 Lamar TR, Lautens LL, Chiou XG, Sharp JD, Young WS, Sprague DL, Ross LS, Felder CC. 58 Cytosolic phospholipase A2 (cPLA2) distribution in murine brain and functional studies indicate that cPLA2 does not participate in muscarinic receptor-mediated signaling in neurons Journal of Physiology-Paris. 92: 454. DOI: 10.1016/S0928-4257(99)80070-9  1
1998 Felder CC, Joon JH, Briley EM, Wood MW. 32 Muscarinic receptor-activated arachidonic acid release is enhanced by cytokines in A2058 human melanoma cells Journal of Physiology-Paris. 92: 431. DOI: 10.1016/S0928-4257(99)80044-8  1
1997 Singer-Lahat D, Rojas E, Felder CC. A9 fibroblasts transfected with the m3 muscarinic receptor clone express a Ca2+ channel activated by carbachol, GTP and GDP. The Journal of Membrane Biology. 159: 21-8. PMID 9309207 DOI: 10.1007/S002329900265  1
1997 Glass M, Felder CC. Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Augments cAMP Accumulation in Striatal Neurons: Evidence for a Gs Linkage to the CB1 Receptor The Journal of Neuroscience. 17: 5327-5333. DOI: 10.1523/Jneurosci.17-14-05327.1997  1
1996 Singer-Lahat D, Rojas E, Felder CC. Muscarinic receptor activated Ca2+ channels in non-excitable cells. Progress in Brain Research. 109: 195-9. PMID 9009707 DOI: 10.1016/S0079-6123(08)62102-0  1
1996 Felder CC, Nielsen A, Briley EM, Palkovits M, Priller J, Axelrod J, Nguyen DN, Richardson JM, Riggin RM, Koppel GA, Paul SM, Becker GW. Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. Febs Letters. 393: 231-5. PMID 8814296 DOI: 10.1016/0014-5793(96)00891-5  1
1996 Kohn EC, Alessandro R, Probst J, Jacobs W, Brilley E, Felder CC. Identification and Molecular Characterization of a m5 Muscarinic Receptor in A2058 Human Melanoma Cells COUPLING TO INHIBITION OF ADENYLYL CYCLASE AND STIMULATION OF PHOSPHOLIPASE A2 Journal of Biological Chemistry. 271: 17476-17484. PMID 8663391 DOI: 10.1074/Jbc.271.29.17476  1
1996 Singer-Lahat D, Ma AL, Felder CC. Independent induction of morphological transformation of CHO cells by receptor-activated cyclic AMP synthesis or by receptor-operated calcium influx. Biochemical Pharmacology. 51: 495-502. PMID 8619896 DOI: 10.1016/0006-2952(95)02226-0  1
1995 Jose PA, Yu PY, Yamaguchi I, Eisner GM, Mouradian MM, Felder CC, Felder RA. Dopamine D1 receptor regulation of phospholipase C. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 18: S39-42. PMID 8529072 DOI: 10.1291/Hypres.18.Supplementi_S39  1
1995 Lolait SJ, O'Carroll AM, Mahan LC, Felder CC, Button DC, Young WS, Mezey E, Brownstein MJ. Extrapituitary expression of the rat V1b vasopressin receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 6783-7. PMID 7624319 DOI: 10.1073/Pnas.92.15.6783  1
1995 Garces Y, Briley EM, Felder CC. Vasopressin via receptor-stimulated phospholipase D: Differential regulation of transphosphatidylation and phospholipid hydrolysis by protein kinase C Neuropeptides. 28: 277-285. PMID 7603588 DOI: 10.1016/0143-4179(95)90044-6  1
1995 Felder CC. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. The Faseb Journal. 9: 619-625. DOI: 10.1096/Fasebj.9.8.7768353  0.01
1994 Briley EM, Lolait SJ, Axelrod J, Felder CC. The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels. Neuropeptides. 27: 63-74. PMID 7969820 DOI: 10.1016/0143-4179(94)90017-5  1
1994 Felder CC, Singer-Lahat D, Mathes C. Voltage-independent calcium channels: Regulation by receptors and intracellular calcium stores Biochemical Pharmacology. 48: 1997-2004. PMID 7802688 DOI: 10.1016/0006-2952(94)90498-7  1
1993 Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 90: 7656-60. PMID 8395053 DOI: 10.1073/Pnas.90.16.7656  1
1993 Felder CC, Ma AL, Briley EM, Axelrod J. Muscarinic acetylcholine receptor subtypes associated with release of Alzheimer amyloid precursor derivatives activate multiple signal transduction pathways. Annals of the New York Academy of Sciences. 695: 15-8. PMID 8239275 DOI: 10.1111/J.1749-6632.1993.Tb23020.X  1
1993 Nitsch RM, Slack BE, Farber SA, Borghesani PR, Schulz JG, Kim C, Felder CC, Growdon JH, Wurtman RJ. Receptor-coupled amyloid precursor protein processing. Annals of the New York Academy of Sciences. 695: 122-7. PMID 8239269 DOI: 10.1111/J.1749-6632.1993.Tb23039.X  1
1993 Wisden W, Parker EM, Mahle CD, Grisel DA, Nowak HP, Yocca FD, Felder CC, Seeburg PH, Voigt MM. Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. Febs Letters. 333: 25-31. PMID 8224165 DOI: 10.1016/0014-5793(93)80368-5  1
1993 Felder CC, Albrecht FE, Campbell T, Eisner GM, Jose PA. cAMP-independent, G protein-linked inhibition of Na+/H+ exchange in renal brush border by D1 dopamine agonists. The American Journal of Physiology. 264: F1032-7. PMID 8100686 DOI: 10.1152/AJPRENAL.1993.264.6.F1032  1
1993 Crawley JN, Corwin RL, Robinson JK, Felder CC, Devane WA, Axelrod J. Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents. Pharmacology, Biochemistry, and Behavior. 46: 967-72. PMID 7906042 DOI: 10.1016/0091-3057(93)90230-Q  1
1993 Felder CC, MacArthur L, Ma AL, Gusovsky F, Kohn EC. Tumor-suppressor function of muscarinic acetylcholine receptors is associated with activation of receptor-operated calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 90: 1706-10. PMID 7680475 DOI: 10.1073/Pnas.90.5.1706  1
1992 Uhlén S, Xia Y, Chhajlani V, Felder CC, Wikberg JES. [3H]‐MK 912 binding delineates two α2‐adrenoceptor subtypes in rat CNS one of which is identical with the cloned pA2d α2‐adrenoceptor British Journal of Pharmacology. 106: 986-995. PMID 1356570 DOI: 10.1111/J.1476-5381.1992.Tb14446.X  0.01
1991 Voigt MM, McCune SK, Kanterman RY, Felder CC. The rat alpha 2-C4 adrenergic receptor gene encodes a novel pharmacological subtype. Febs Letters. 278: 45-50. PMID 1704314 DOI: 10.1016/0014-5793(91)80080-M  1
1991 Felder CC, Williams HL, Axelrod J. A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release. Proceedings of the National Academy of Sciences of the United States of America. 88: 6477-80. PMID 1650470 DOI: 10.1073/Pnas.88.15.6477  1
1990 Felder CC, Kanterman RY, Ma AL, Axelrod J. Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 87: 2187-91. PMID 2315313 DOI: 10.1073/Pnas.87.6.2187  1
1990 Kanterman RY, Felder CC, Brenneman DE, Ma AL, Fitzgerald S, Axelrod J. Alpha 1-adrenergic receptor mediates arachidonic acid release in spinal cord neurons independent of inositol phospholipid turnover. Journal of Neurochemistry. 54: 1225-32. PMID 2156016 DOI: 10.1111/J.1471-4159.1990.Tb01952.X  1
1990 Kanterman RY, Ma AL, Briley EM, Axelrod J, Felder CC. Muscarinic receptors mediate the release of arachidonic acid from spinal cord and hippocampal neurons in primary culture. Neuroscience Letters. 118: 235-7. PMID 2125713 DOI: 10.1016/0304-3940(90)90635-M  1
1990 Jose PA, Felder RA, Felder CC, Chan W. Molecular biology of adrenergic and dopamine receptors and the study of developmental nephrology Pediatric Nephrology. 4: 679-685. PMID 1982417 DOI: 10.1007/Bf00858648  1
1990 Felder CC, Piccio MM, McKelvey AM, Nakamura KT, Robillard JE, Jose PA. Ontogeny of renal beta adrenoceptors in the sheep. Pediatric Nephrology (Berlin, Germany). 4: 635-9. PMID 1982416 DOI: 10.1007/Bf00858641  1
1990 Felder CC, Campbell T, Albrecht F, Jose PA. Dopamine inhibits Na(+)-H+ exchanger activity in renal BBMV by stimulation of adenylate cyclase. The American Journal of Physiology. 259: F297-303. PMID 1974737 DOI: 10.1152/AJPRENAL.1990.259.2.F297  1
1990 Felder CC, Albrecht F, Eisner GM, Jose PA. The signal transducer for the dopamine-1 regulated sodium transport in renal cortical brush border membrane vesicles. American Journal of Hypertension. 3: 47S-50S. PMID 1974443 DOI: 10.1093/Ajh/3.6.47S  1
1990 Cox JA, Felder CC, Henneberry RC. Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons. Neuron. 4: 941-947. PMID 1972886 DOI: 10.1016/0896-6273(90)90147-8  0.04
1990 Brunswick M, Bonvini E, Francis M, Felder CC, Hoffman T, Mond J. Absence of demonstrable phospholipid turnover in B cells stimulated by low mitogenic concentrations of dextran-anti-immunoglobulin conjugates. European Journal of Immunology. 20: 855-861. PMID 1693337 DOI: 10.1002/Eji.1830200421  0.01
1989 Felder RA, Felder CC, Eisner GM, Jose PA. The dopamine receptor in adult and maturing kidney. American Journal of Physiology-Renal Physiology. 257. PMID 2571302 DOI: 10.1152/Ajprenal.1989.257.3.F315  1
1989 Felder CC, McKelvey AM, Gitler MS, Eisner GM, Jose PA. Dopamine receptor subtypes in renal brush border and basolateral membranes. Kidney International. 36: 183-93. PMID 2528652 DOI: 10.1038/Ki.1989.178  1
1989 Felder CC, Ma AL, Conklin BR. Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor. Febs Letters. 245: 75-9. PMID 2466702 DOI: 10.1016/0014-5793(89)80195-4  1
1987 Felder CC, Robillard JE, Roy S, Jose PA. Severe Chloride Deficiency in the Neonate: The Canine Puppy as an Animal Model Pediatric Research. 21: 497-501. PMID 3588090 DOI: 10.1203/00006450-198705000-00015  1
1987 McKelvey T, Felder C, Nakamura K, Robillard J, Jose P. MULTIPLE β -ADRENOCEPTORS ARE PRESENT IN ADULT BUT NOT FETAL SHEEP KIDNEYS Pediatric Research. 21: 218-218. DOI: 10.1203/00006450-198704010-00310  0.01
1985 Felder CC, Felder RA, Holloway RR, Robillard JE, Jose PA. 1592 Function Of Renal Dopamine-2 Receptors Pediatric Research. 19: 376-376. DOI: 10.1203/00006450-198504000-01616  1
Show low-probability matches.