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Arthur H. Rubenstein - Publications

Affiliations: 
Endocrinology, Diabetes and Metabolism University of Pennsylvania, Philadelphia, PA, United States 
Area:
diabetes
Website:
http://www.med.upenn.edu/apps/faculty/index.php/g275/p49919
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Year Citation  Score
2015 Polonsky KS, Rubenstein AH. Donald F. Steiner, MD, 1930-2014: pioneering diabetes researcher. Diabetologia. 58: 419-21. PMID 25617020 DOI: 10.1007/S00125-015-3495-X  0.489
2015 Polonsky KS, Rubenstein AH. Donald F. Steiner, MD, 1930–2014: Pioneering diabetes researcher Diabetologia. 58: 419-421. DOI: 10.1007/s00125-015-3495-x  0.429
2011 Steiner DF, Chan SJ, Rubenstein AH. Biosynthesis of Insulin Comprehensive Physiology. 49-78. DOI: 10.1002/Cphy.Cp070203  0.543
1997 Steiner DF, Rubenstein AH. Proinsulin C-peptide-biological activity? Science. 277: 531-532. PMID 9254422 DOI: 10.1126/Science.277.5325.531  0.442
1993 Levitt NS, Hirsch L, Rubenstein AH, Polonsky KS. Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man Metabolism. 42: 829-833. PMID 8345793 DOI: 10.1016/0026-0495(93)90054-R  0.659
1993 Levitt NS, Hirsch L, Rubenstein AH, Polonsky KS. Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man Metabolism. 42: 829-833. PMID 8345793 DOI: 10.1016/0026-0495(93)90054-R  0.354
1993 Elahi D, McAloon-Dyke M, Fukagawa NK, Sclater AL, Wong GA, Shannon RP, Minaker KL, Miles JM, Rubenstein AH, Vandepol CJ. Effects of recombinant human IGF-I on glucose and leucine kinetics in men. The American Journal of Physiology. 265: E831-8. PMID 8279537  0.478
1993 Elahi D, McAloon-Dyke M, Fukagawa NK, Sclater AL, Wong GA, Shannon RP, Minaker KL, Miles JM, Rubenstein AH, Vandepol CJ, Guler HP, Good WR, Seaman JJ, Wolfe RR. Effects of recombinant human IGF-I on glucose and leucine kinetics in men Am.J.Physiol.. 265: E831-E838.  0.326
1991 Given BD, Ostrega DM, Polonsky KS, Baldwin D, Kelley RI, Rubenstein AH. Hypoglycemia due to surreptitious injection of insulin: Identification of insulin species by high-performance liquid chromatography Diabetes Care. 14: 544-547. PMID 1914793 DOI: 10.2337/Diacare.14.7.544  0.683
1991 Given BD, Ostrega DM, Polonsky KS, Baldwin D, Kelley RI, Rubenstein AH. Hypoglycemia due to surreptitious injection of insulin: Identification of insulin species by high-performance liquid chromatography Diabetes Care. 14: 544-547. PMID 1914793  0.472
1990 Tillil H, Frank BH, Pekar AH, Broelsch C, Rubenstein AH, Polonsky KS. Hypoglycemic potency and metabolic clearance rate of intravenously administered human proinsulin and metabolites Endocrinology. 127: 2418-2422. PMID 2226325 DOI: 10.1210/Endo-127-5-2418  0.663
1990 Beebe CA, Van Cauter E, Shapiro ET, Tillil H, Lyons R, Rubenstein AH, Polonsky KS. Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM Diabetes Care. 13: 748-755. PMID 2201497 DOI: 10.2337/Diacare.13.7.748  0.736
1990 Beebe CA, Van Cauter E, Shapiro ET, Tillil H, Lyons R, Rubenstein AH, Polonsky KS. Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM Diabetes Care. 13: 748-755. PMID 2201497  0.432
1990 Wojcikowski C, Blackman J, Ostrega D, Lewis G, Galloway J, Rubenstein AH, Polonsky KS. Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects Metabolism. 39: 827-832. PMID 2198434 DOI: 10.1016/0026-0495(90)90127-X  0.71
1990 Steiner DF, Tager HS, Chan SJ, Nanjo K, Sanke T, Rubenstein AH. Lessons learned from molecular biology of insulin-gene mutations. Diabetes Care. 13: 600-9. PMID 2192846 DOI: 10.2337/Diacare.13.6.600  0.739
1990 Shapiro ET, Bell GI, Polonsky KS, Rubenstein AH, Kew MC, Tager HS. Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-II. The Journal of Clinical Investigation. 85: 1672-9. PMID 2159026 DOI: 10.1172/Jci114619  0.72
1990 Shapiro ET, Bell GI, Polonsky KS, Rubenstein AH, Kew MC, Tager HS. Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-II. The Journal of Clinical Investigation. 85: 1672-9. PMID 2159026 DOI: 10.1172/Jci114619  0.72
1989 Shapiro ET, Van Cauter E, Tillil H, Given BD, Hirsch L, Beebe C, Rubenstein AH, Polonsky KS. Glyburide enhances the responsiveness of the β-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 69: 571-576. PMID 2503533 DOI: 10.1210/Jcem-69-3-571  0.691
1989 Shapiro ET, Van Cauter E, Tillil H, Given BD, Hirsch L, Beebe C, Rubenstein AH, Polonsky KS. Glyburide enhances the responsiveness of the β-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 69: 571-576. PMID 2503533  0.404
1988 Herold KC, Rubenstein AH. Immunosuppression for insulin-dependent diabetes New England Journal of Medicine. 318: 701-703. PMID 3344022 DOI: 10.1056/NEJM198803173181110  0.432
1988 Herold KC, Rubenstein AH. Immunosuppression for insulin-dependent diabetes New England Journal of Medicine. 318: 701-703. PMID 3344022  0.432
1988 Shapiro ET, Tillil H, Polonsky KS, Fang VS, Rubenstein AH, Van Cauter E. Oscillations in insulin secretion during constant glucose infusion in normal man: Relationship to changes in plasma glucose Journal of Clinical Endocrinology and Metabolism. 67: 307-314. PMID 3292558 DOI: 10.1210/Jcem-67-2-307  0.716
1988 Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion Diabetes. 37: 590-599. PMID 3282946 DOI: 10.2337/Diab.37.5.590  0.56
1988 Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion Diabetes. 37: 590-599. PMID 3282946  0.429
1988 Tillil H, Shapiro ET, Miller MA, Karrison T, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans American Journal of Physiology - Gastrointestinal and Liver Physiology. 254: 17/3. PMID 3279811 DOI: 10.1152/Ajpendo.1988.254.3.E349  0.698
1988 Casper RC, Pandey G, Jaspan JB, Rubenstein AH. Eating attitudes and glucose tolerance in anorexia nervosa patients at 8-year followup compared to control subjects Psychiatry Research. 25: 283-299. PMID 3054985 DOI: 10.1016/0165-1781(88)90099-6  0.5
1988 Shapiro ET, Tillil H, Rubenstein AH, Polonsky KS. Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration Journal of Clinical Endocrinology and Metabolism. 67: 1094-1099. PMID 3053748 DOI: 10.1210/Jcem-67-5-1094  0.717
1988 Casper RC, Pandy GN, Jaspan JB, Rubenstein AH. Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls Biological Psychiatry. 24: 663-674. PMID 3048427 DOI: 10.1016/0006-3223(88)90140-0  0.362
1988 Tillil H, Shapiro ET, Rubenstein AH, Galloway JA, Polonsky KS. Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans Diabetes. 37: 1351-1357. PMID 3046967 DOI: 10.2337/Diab.37.10.1351  0.752
1988 Tillil H, Shapiro ET, Rubenstein AH, Galloway JA, Polonsky KS. Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans Diabetes. 37: 1351-1357. PMID 3046967  0.421
1988 Tillil H, Shapiro ET, Given BD, Rue P, Rubenstein AH, Galloway JA, Polonsky KS. Reevaluation of urine C-peptide as measure of insulin secretion Diabetes. 37: 1195-1201. PMID 3044885 DOI: 10.2337/Diab.37.9.1195  0.699
1988 Tillil H, Shapiro ET, Given BD, Rue P, Rubenstein AH, Galloway JA, Polonsky KS. Reevaluation of urine C-peptide as measure of insulin secretion Diabetes. 37: 1195-1201. PMID 3044885  0.539
1988 Given BD, Mostrom MS, Tully R, Ditkowsky N, Rubenstein AH. Severe hypoglycemia attributable to surreptitious injection of insulin in a mare. Journal of the American Veterinary Medical Association. 193: 224-226. PMID 3042728  0.463
1988 Given BD, Mostrom MS, Tully R, Ditkowsky N, Rubenstein AH. Severe hypoglycemia attributable to surreptitious injection of insulin in a mare. Journal of the American Veterinary Medical Association. 193: 224-226. PMID 3042728  0.493
1987 Nanjo K, Miyano M, Kondo M, Sanke T, Nishimura S, Miyamura K, Inouye K, Given BD, Chan SJ, Polonsky KS, Tager HS, Steiner DF, Rubenstein AH. Insulin Wakayama: familial mutant insulin syndrome in Japan Diabetologia. 30: 87-92. PMID 3552828 DOI: 10.1007/Bf00274577  0.807
1987 Nanjo K, Miyano M, Kondo M, Sanke T, Nishimura S, Miyamura K, Inouye K, Given BD, Chan SJ, Polonsky KS, Tager HS, Steiner DF, Rubenstein AH. Insulin Wakayama: familial mutant insulin syndrome in Japan Diabetologia. 30: 87-92. PMID 3552828 DOI: 10.1007/Bf00274577  0.807
1987 Cohen RM, Licinio J, Polonsky KS, Galloway JA, Frank BH, Cherrington AD, Rubenstein AH. The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes Journal of Clinical Endocrinology and Metabolism. 64: 476-481. PMID 3546347 DOI: 10.1210/Jcem-64-3-476  0.71
1987 Cohen RM, Licinio J, Polonsky KS, Galloway JA, Frank BH, Cherrington AD, Rubenstein AH. The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes Journal of Clinical Endocrinology and Metabolism. 64: 476-481. PMID 3546347  0.421
1987 Shapiro ET, Tillil H, Miller MA, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Insulin secretion and clearance. Comparison after oral and intravenous glucose Diabetes. 36: 1365-1371. PMID 3315785 DOI: 10.2337/Diab.36.12.1365  0.717
1987 Shapiro ET, Tillil H, Miller MA, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Insulin secretion and clearance. Comparison after oral and intravenous glucose Diabetes. 36: 1365-1371. PMID 3315785  0.489
1987 Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Selective suppression of hepatic glucose output by human proinsulin in the dog American Journal of Physiology - Endocrinology and Metabolism. 252: 15/2. PMID 2881485 DOI: 10.1152/Ajpendo.1987.252.2.E230  0.545
1987 Rubenstein AH, Pyke D. Immunosuppression in the treatment of insulin-dependent (type 1) diabetes Lancet. 1: 436-437. PMID 2880226  0.389
1987 Rubenstein AH, Pyke D. Immunosuppression in the treatment of insulin-dependent (type 1) diabetes Lancet. 1: 436-437. PMID 2880226  0.389
1986 Licinio-Paixao J, Polonsky KS, Given BD, Pugh W, Ostrega D, Frank BF, Rubenstein AH. Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide Journal of Clinical Endocrinology and Metabolism. 63: 401-403. PMID 3722329 DOI: 10.1210/Jcem-63-2-401  0.638
1986 Steiner DF, Chan SJ, Welsh JM, Nielsen D, Michael J, Tager HS, Rubenstein AH. Models of peptide biosynthesis: the molecular and cellular basis of insulin production. Clinical and Investigative Medicine. Mã©Decine Clinique Et Experimentale. 9: 328-36. PMID 3542328  0.705
1986 Polonsky KS, Rubenstein AH. Current approaches to measurement of insulin secretion Diabetes/Metabolism Reviews. 2: 315-329. PMID 3527618 DOI: 10.1002/Dmr.5610020306  0.69
1986 Polonsky KS, Rubenstein AH. Current approaches to measurement of insulin secretion Diabetes/Metabolism Reviews. 2: 315-329. PMID 3527618  0.438
1986 Polonsky KS, Given BD, Pugh W, Licinio-Paixao J, Thompson JE, Karrison T, Rubenstein AH. Calculation of the systemic delivery rate of insulin in normal man Journal of Clinical Endocrinology and Metabolism. 63: 113-118. PMID 3519643 DOI: 10.1210/Jcem-63-1-113  0.667
1986 Polonsky KS, Given BD, Pugh W, Licinio-Paixao J, Thompson JE, Karrison T, Rubenstein AH. Calculation of the systemic delivery rate of insulin in normal man Journal of Clinical Endocrinology and Metabolism. 63: 113-118. PMID 3519643  0.398
1986 Polonsky K, Frank B, Pugh W, Addis A, Karrison T, Meier P, Tager H, Rubenstein A. The limitations to and valid use of C-peptide as a marker of the secretion of insulin Diabetes. 35: 379-386. PMID 3514322 DOI: 10.2337/Diab.35.4.379  0.782
1986 Glauber HS, Revers RR, Henry R, Schmeiser L, Wallace P, Kolterman OG, Cohen RM, Rubenstein AH, Galloway JA, Frank BH. In vivo deactivation of proinsulin action on glucose disposal and hepatic glucose production in normal man Diabetes. 35: 311-317. PMID 3512341 DOI: 10.2337/Diab.35.3.311  0.597
1986 Shoelson SE, Marshall S, Horikoshi H, Kolterman OG, Rubenstein AH, Olefsky JM. Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes. The Journal of Clinical Endocrinology and Metabolism. 63: 56-61. PMID 3486878 DOI: 10.1210/Jcem-63-1-56  0.671
1986 Shoelson SE, Marshall S, Horikoshi H, Kolterman OG, Rubenstein AH, Olefsky JM. Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes. The Journal of Clinical Endocrinology and Metabolism. 63: 56-61. PMID 3486878 DOI: 10.1210/Jcem-63-1-56  0.671
1986 Mako ME, Rubenstein AH. Insulin and diabetes. Transactions of the Association of American Physicians. 99: clxxxix-ccxi. PMID 3299979  0.436
1986 Mako ME, Rubenstein AH. Insulin and diabetes. Transactions of the Association of American Physicians. 99: clxxxix-ccxi. PMID 3299979  0.436
1986 Cohen RM, Given BD, Licinio-Paixao J, Provow SA, Rue PA, Frank BH, Root MA, Polonsky KS, Tager HS, Rubenstein AH. Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism: Clinical and Experimental. 35: 1137-46. PMID 3023795 DOI: 10.1016/0026-0495(86)90027-2  0.765
1986 Cohen RM, Given BD, Licinio-Paixao J, Provow SA, Rue PA, Frank BH, Root MA, Polonsky KS, Tager HS, Rubenstein AH. Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism: Clinical and Experimental. 35: 1137-46. PMID 3023795 DOI: 10.1016/0026-0495(86)90027-2  0.765
1985 Bergenstal RM, Dupre J, Lawson PM, Rizza RA, Rubenstein AH. Observations on C-peptide and free insulin in the blood during continuous subcutaneous insulin infusion and conventional insulin therapy. Diabetes. 34: 31-36. PMID 3926568  0.578
1985 Bergenstal RM, Dupre J, Lawson PM, Rizza RA, Rubenstein AH. Observations on C-peptide and free insulin in the blood during continuous subcutaneous insulin infusion and conventional insulin therapy. Diabetes. 34: 31-36. PMID 3926568  0.573
1985 Given BD, Cohen RM, Shoelson SE, Frank BH, Rubenstein AH, Tager HS. Biochemical and clinical implications of proinsulin conversion intermediates. The Journal of Clinical Investigation. 76: 1398-405. PMID 3902891 DOI: 10.1172/Jci112116  0.784
1985 Given BD, Cohen RM, Shoelson SE, Frank BH, Rubenstein AH, Tager HS. Biochemical and clinical implications of proinsulin conversion intermediates. The Journal of Clinical Investigation. 76: 1398-405. PMID 3902891 DOI: 10.1172/Jci112116  0.784
1985 Garvey WT, Revers RR, Kolterman OG, Rubenstein AH, Olefsky JM. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 60: 559-568. PMID 3882736 DOI: 10.1210/Jcem-60-3-559  0.595
1985 Garvey WT, Revers RR, Kolterman OG, Rubenstein AH, Olefsky JM. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 60: 559-568. PMID 3882736  0.496
1985 Cohen RM, Nakabayashi T, Blix PM, Rue PA, Shoelson SE, Root MA, Frank BH, Revers RR, Rubenstein AH. A radioimmunoassay for circulating human proinsulin. Diabetes. 34: 84-91. PMID 3880551 DOI: 10.2337/Diab.34.1.84  0.695
1985 Cohen RM, Nakabayashi T, Blix PM, Rue PA, Shoelson SE, Root MA, Frank BH, Revers RR, Rubenstein AH. A radioimmunoassay for circulating human proinsulin. Diabetes. 34: 84-91. PMID 3880551 DOI: 10.2337/Diab.34.1.84  0.695
1984 Polonsky KS, Pugh W, Jaspan JB, Cohen DM, Karrison T, Tager HS, Rubenstein AH. C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. The Journal of Clinical Investigation. 74: 1821-9. PMID 6389599 DOI: 10.1172/Jci111601  0.753
1984 Polonsky KS, Pugh W, Jaspan JB, Cohen DM, Karrison T, Tager HS, Rubenstein AH. C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. The Journal of Clinical Investigation. 74: 1821-9. PMID 6389599 DOI: 10.1172/Jci111601  0.753
1984 Naithani VK, Steffens GJ, Tager HS, Buse G, Rubenstein AH, Steiner DF. Isolation and amino-acid sequence determination of monkey insulin and proinsulin. Hoppe-Seyler's Zeitschrift Fã¼R Physiologische Chemie. 365: 571-5. PMID 6381277 DOI: 10.1515/Bchm2.1984.365.1.571  0.7
1984 Naithani VK, Steffens GJ, Tager HS, Buse G, Rubenstein AH, Steiner DF. Isolation and amino-acid sequence determination of monkey insulin and proinsulin. Hoppe-Seyler's Zeitschrift Fã¼R Physiologische Chemie. 365: 571-5. PMID 6381277 DOI: 10.1515/Bchm2.1984.365.1.571  0.7
1984 Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Bergenstal R, Polonsky K, Jaspan J, Rubenstein A, Frank B. The effects of biosynthetic human proinsulin on carbohydrate metabolism Diabetes. 33: 762-770. PMID 6378699 DOI: 10.2337/Diab.33.8.762  0.682
1984 Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Rubenstein A, Frank B, Galloway J, Olefsky JM. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal Journal of Clinical Endocrinology and Metabolism. 58: 1094-1098. PMID 6373809 DOI: 10.1210/Jcem-58-6-1094  0.552
1984 Polonsky KS, Rubenstein AH. C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations Diabetes. 33: 486-494. PMID 6373457 DOI: 10.2337/Diab.33.5.486  0.758
1984 Polonsky KS, Rubenstein AH. C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations Diabetes. 33: 486-494. PMID 6373457  0.496
1984 Shoelson SE, Polonsky KS, Zeidler A, Rubenstein AH, Tager HS. Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. The Journal of Clinical Investigation. 73: 1351-8. PMID 6371057 DOI: 10.1172/Jci111338  0.841
1984 Shoelson SE, Polonsky KS, Zeidler A, Rubenstein AH, Tager HS. Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. The Journal of Clinical Investigation. 73: 1351-8. PMID 6371057 DOI: 10.1172/Jci111338  0.841
1984 Robbins DC, Tager HS, Rubenstein AH. Biologic and clinical importance of proinsulin. The New England Journal of Medicine. 310: 1165-75. PMID 6369137 DOI: 10.1056/Nejm198405033101807  0.678
1984 Robbins DC, Tager HS, Rubenstein AH. Biologic and clinical importance of proinsulin. The New England Journal of Medicine. 310: 1165-75. PMID 6369137 DOI: 10.1056/Nejm198405033101807  0.678
1984 Robbins DC, Shoelson SE, Rubenstein AH, Tager HS. Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion. The Journal of Clinical Investigation. 73: 714-9. PMID 6368587 DOI: 10.1172/Jci111264  0.786
1984 Robbins DC, Shoelson SE, Rubenstein AH, Tager HS. Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion. The Journal of Clinical Investigation. 73: 714-9. PMID 6368587 DOI: 10.1172/Jci111264  0.786
1984 Herold KC, Huen A, Gould L, Traisman H, Rubenstein AH. Alterations in lymphocyte subpopulations in type 1 (insulin-dependent) diabetes mellitus: exploration of possible mechanisms and relationships to autoimmune phenomena Diabetologia. 27: 102-105. PMID 6237011 DOI: 10.1007/BF00275660  0.363
1983 Bergenstal RM, Polonsky KS, Pons G, Jaspan JB, Rubenstein AH. Lack of glucagon response to hypoglycemia in type I diabetics after long-term optimal therapy with a continuous subcutaneous insulin infusion pump. Diabetes. 32: 398-402. PMID 6840400  0.661
1983 Shoelson S, Fickova M, Haneda M, Nahum A, Musso G, Kaiser ET, Rubenstein AH, Tager H. Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution. Proceedings of the National Academy of Sciences of the United States of America. 80: 7390-4. PMID 6424111 DOI: 10.1073/Pnas.80.24.7390  0.817
1983 Shoelson S, Fickova M, Haneda M, Nahum A, Musso G, Kaiser ET, Rubenstein AH, Tager H. Identification of a mutant human insulin predicted to contain a serine-for-phenylalanine substitution. Proceedings of the National Academy of Sciences of the United States of America. 80: 7390-4. PMID 6424111 DOI: 10.1073/Pnas.80.24.7390  0.817
1983 Judzewitsch RG, Jaspan JB, Polonsky KS, Weinberg CR, Halter JB, Halar E, Pfeifer MA, Vukadinovic C, Bernstein L, Schneider M, Liang KY, Gabbay KH, Rubenstein AH, Porte D. Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. The New England Journal of Medicine. 308: 119-25. PMID 6401351 DOI: 10.1056/Nejm198301203080302  0.424
1983 Green A, Frank BH, Rubenstein A, Tager H, Olefsky JM. Characteristics of binding of a low affinity, noncooperative insulin ([Leu(B25)]insulin) to IM-9 lymphocytes Endocrinology. 113: 1963-1970. PMID 6357764 DOI: 10.1210/Endo-113-6-1963  0.761
1983 Polonsky K, Jaspan J, Pugh W, Cohen D, Schneider M, Schwartz T, Moossa AR, Tager H, Rubenstein AH. Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction. The Journal of Clinical Investigation. 72: 1114-23. PMID 6350363 DOI: 10.1172/Jci111036  0.783
1983 Huen AH, Haneda M, Freedman Z, Lernmark A, Rubenstein AH. Quantitative determination of islet cell surface antibodies using 125I-protein A. Diabetes. 32: 460-5. PMID 6341129 DOI: 10.2337/Diab.32.5.460  0.363
1983 Shoelson S, Haneda M, Blix P, Nanjo A, Sanke T, Inouye K, Steiner D, Rubenstein A, Tager H. Three mutant insulins in man Nature. 302: 540-543. PMID 6339950 DOI: 10.1038/302540A0  0.807
1983 Kwok SC, Steiner DF, Rubenstein AH, Tager HS. Identification of a point mutation in the human insulin gene giving rise to a structurally abnormal insulin (insulin Chicago). Diabetes. 32: 872-5. PMID 6313457 DOI: 10.2337/Diab.32.9.872  0.744
1983 Haneda M, Chan SJ, Kwok SC, Rubenstein AH, Steiner DF. Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin. Proceedings of the National Academy of Sciences of the United States of America. 80: 6366-70. PMID 6312455 DOI: 10.1073/Pnas.80.20.6366  0.409
1983 Haneda M, Chan SJ, Kwok SC, Rubenstein AH, Steiner DF. Studies on mutant human insulin genes: identification and sequence analysis of a gene encoding [SerB24]insulin. Proceedings of the National Academy of Sciences of the United States of America. 80: 6366-70. PMID 6312455 DOI: 10.1073/Pnas.80.20.6366  0.409
1982 Roth SI, Schedewie HK, Bier DM, Conaway HH, Olefsky J, Rubenstein A, Elders MJ. Hepatic ultrastructure in leprechaunism - Hepatic ultrastructural evidence suggesting a syndrome with defective hepatic glucose release Virchows Archiv a Pathological Anatomy and Histology. 397: 121-130. PMID 7179734 DOI: 10.1007/Bf00442383  0.323
1982 Elders MJ, Schedewie HK, Olefsky J, Givens B, Char F, Bier DM, Baldwin D, Fiser RH, Seyedabadi S, Rubenstein A. Endocrine-metabolic relationships in patients with leprechaunism. Journal of the National Medical Association. 74: 1195-210. PMID 7154104  0.437
1982 Polonsky K, Bergenstal R, Pons G, Schneider M, Jaspan J, Rubenstein A. Relation of counterregulatory responses to hypoglycemia in Type I diabetics New England Journal of Medicine. 307: 1106-1112. PMID 7121528 DOI: 10.1056/Nejm198210283071802  0.65
1982 Kanatsuna T, Freedman ZR, Rubenstein AH, Lernmark A. Effects of islet cell surface antibodies and complement on the release of insulin and chromium from perifused beta cells. Clinical and Experimental Immunology. 47: 85-92. PMID 7047026  0.314
1982 Widness JA, Cowett RM, Zeller WP, Susa JB, Rubenstein AH, Schwartz R. Permanent neonatal diabetes in an infant of an insulin-dependent mother. The Journal of Pediatrics. 100: 926-9. PMID 7045311 DOI: 10.1016/S0022-3476(82)80517-9  0.302
1982 Scarlett JA, Kolterman OG, Moore P, Saekow M, Insel J, Griffin J, Mako M, Rubenstein AH, Olefsky JM. Insulin resistance and diabetes due to a genetic defect in insulin receptors. The Journal of Clinical Endocrinology and Metabolism. 55: 123-31. PMID 7042734 DOI: 10.1210/Jcem-55-1-123  0.616
1982 Elahi D, Nagulesparan M, Hershcopf RJ, Muller DC, Tobin JD, Blix PM, Rubenstein AH, Unger RH, Andres R. Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity. The New England Journal of Medicine. 306: 1196-202. PMID 7040963 DOI: 10.1056/Nejm198205203062002  0.475
1982 Hidaka H, Nagulesparan M, Klimes I, Clark R, Sasaki H, Aronoff SL, Vasquez B, Rubenstein AH, Unger RH. Improvement of insulin secretion but not insulin resistance after short term control of plasma glucose in obese type II diabetics. The Journal of Clinical Endocrinology and Metabolism. 54: 217-22. PMID 7033272 DOI: 10.1210/jcem-54-2-217  0.54
1982 Pickup JC, Bilous RW, Viberti GC, Keen H, Jarrett RJ, Glynne A, Cauldwell J, Root M, Rubenstein AH. Plasma insulin and C-peptide after subcutaneous and intravenous administration of human insulin (recombinant DNA) and purified porcine insulin in healthy men. Diabetes Care. 5: 29-34. PMID 6765536 DOI: 10.2337/Diacare.5.2.S29  0.614
1982 Martin MJ, Robbins DC, Bergenstal R, LaGrange B, Rubenstein AH. Absence of exercise-induced hypoglycaemia in type i (insulin-dependent) diabetic patients during maintenance of normoglycaemia by short-term, open-loop insulin infusion. Diabetologia. 23: 336-42. PMID 6754517 DOI: 10.1007/BF00253741  0.418
1982 Blei AT, Robbins DC, Drobny E, Baumann G, Rubenstein AH. Insulin resistance and insulin receptors in hepatic cirrhosis. Gastroenterology. 83: 1191-9. PMID 6751926  0.514
1982 Green A, Tager H, Rubenstein A, Frank B, Olefsky JM. Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes Febs Letters. 144: 255-258. PMID 6749549 DOI: 10.1016/0014-5793(82)80649-2  0.727
1982 Bonnevie-Nielsen V, Polonsky KS, Jaspan JJ, Rubenstein AH, Schwartz TW, Tager HS. Surface receptors for pancreatic hormones in dog and rat hepatocytes: qualitative and quantitative differences in hormone-target cell interactions. Proceedings of the National Academy of Sciences of the United States of America. 79: 2167-71. PMID 6285368 DOI: 10.1073/Pnas.79.7.2167  0.689
1982 Joffe BI, Kew MC, Heding LG, Rubenstein AH, Pons G, Seftel HC. Nonspecific blinding of insulin to gamma globulin in the serum of black patients with hepatocellular carcinoma and other forms of liver disease. The Journal of Laboratory and Clinical Medicine. 100: 445-50. PMID 6180112  0.306
1982 Shoelson S, Polonsky K, Docherty H, Jaspan J, Rubenstein A. Evidence for the presence of somatostatin 28 in plasma Diabetes. 31: 474-477. PMID 6130021 DOI: 10.2337/Diab.31.5.474  0.649
1981 Jaspan JB, Polonsky KS, Röjdmark S, Ishida T, Field JB, Rubenstein AH. Hepatic extraction of plasma immunoreactive glucagon components. Predilection for 3500-dalton glucagon metabolism by the liver. Diabetes. 30: 767-72. PMID 7262472 DOI: 10.2337/Diab.30.9.767  0.513
1981 Robbins DC, Blix PM, Rubenstein AH, Kanazawa Y, Kosaka K, Tager HS. A human proinsulin variant at arginine 65. Nature. 291: 679-81. PMID 7242673 DOI: 10.1038/291679A0  0.761
1981 Olefsky JM, Green A, Ciaraldi TP, Saekow M, Rubenstein AH, Tager HS. Relationship between negative cooperativity and insulin action. Biochemistry. 20: 4488-92. PMID 7025901 DOI: 10.1021/Bi00518A038  0.738
1981 Baldwin D, Prince M, Tsai P, Johnson C, Lotan R, Rubenstein AH, Olefsky JM. Insulin binding, internalization, and receptor regulation in cultured human fibroblasts. The American Journal of Physiology. 241: E251-60. PMID 7025657 DOI: 10.1152/Ajpendo.1981.241.3.E251  0.602
1981 Landau RL, Rochman H, Blix-Gruber P, Rubenstein AH. The protein-sparing action of protein feeding: absence of relationship to insulin secretion. The American Journal of Clinical Nutrition. 34: 1300-4. PMID 7020397  0.443
1981 Jaspan JB, Polonsky KS, Lewis M, Pensler J, Pugh W, Moossa AR, Rubenstein AH. Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon. The American Journal of Physiology. 240: E233-44. PMID 7011049 DOI: 10.1152/Ajpendo.1981.240.3.E233  0.52
1981 Kanatsuna T, Lernmark A, Rubenstein AH, Steiner DF. Block in insulin release from column-perifused pancreatic β-cells induced by islet cell surface antibodies and complement Diabetes. 30: 231-234. PMID 7009272 DOI: 10.2337/Diab.30.3.231  0.413
1981 Lin CC, Moawad AH, River P, Blix P, Abraham M, Rubenstein AH. Amniotic fluid C-peptide as an index for intrauterine fetal growth American Journal of Obstetrics and Gynecology. 139: 390-396. PMID 7008608  0.342
1981 Bergenstal RM, Rubenstein AH. Metabolic Control and Complications in Diabetic Patients Jama: the Journal of the American Medical Association. 245: 735-736. PMID 7007675 DOI: 10.1001/Jama.1981.03310320057030  0.339
1981 Rosenfeld RG, Baldwin D, Dollar LA, Hintz RL, Olefsky JM, Rubenstein A. Simultaneous Inhibition of Insulin and Somatomedin-C Binding to Cultured IM-9 Lymphocytes by Naturally Occurring Antireceptor Antibodies Diabetes. 30: 979-982. PMID 6271619 DOI: 10.2337/Diab.30.11.979  0.566
1981 Kwok SC, Chan SJ, Rubenstein AH, Poucher R, Steiner DF. Loss of a restriction endonuclease cleavage site in the gene of a structurally abnormal human insulin. Biochemical and Biophysical Research Communications. 98: 844-9. PMID 6261753 DOI: 10.1016/0006-291X(81)91188-8  0.492
1981 Rand KH, Rosenbloom AL, Maclaren NK, Silverstein JH, Riley WJ, Butterworth BE, Yoon JW, Rubenstein AH, Merigan TC. Human leukocyte interferon treatment of two children with insulin dependent diabetes. Diabetologia. 21: 116-9. PMID 6167482 DOI: 10.1007/Bf00251277  0.471
1981 Elders MJ, Elsas L, Schedewie H, Herzberg VL, Hill DE, Olefsky J, Rubenstein A. Correlation of metabolic parameters with high and low affinity insulin receptor binding in leprechaunism (L) Pediatric Research. 15: 1566-1566. DOI: 10.1203/00006450-198112000-00189  0.3
1980 Schwartz SS, Corkey B, Williamson JR, Rubenstein AH. Effect of bovine pancreatic polypeptide on isolated rat liver cells Endocrinology. 106: 1178-1181. PMID 7358031 DOI: 10.1210/Endo-106-4-1178  0.303
1980 Given BD, Mako ME, Tager HS, Baldwin D, Markese J, Rubenstein AH, Olefsky J, Kobayashi M, Kolterman O, Poucher R. Diabetes due to secretion of an abnormal insulin. The New England Journal of Medicine. 302: 129-35. PMID 7350438 DOI: 10.1056/Nejm198001173020301  0.769
1980 Keenan BS, Kirland RT, Garber AJ, Rubenstein AH, Holcombe JH, Potts VE, Clayton GW. The effect of diet upon carbohydrate metabolism, insulin resistance, and blood pressure in congenital total lipoatrophic diabetes. Metabolism: Clinical and Experimental. 29: 1214-24. PMID 7005617 DOI: 10.1016/0026-0495(80)90148-1  0.327
1980 Bier DM, Schedewie H, Larner J, Olefsky J, Rubenstein A, Fiser RH, Craig JW, Elders MJ. Glucose kinetics in leprechaunism: accelerated fasting due to insulin resistance. The Journal of Clinical Endocrinology and Metabolism. 51: 988-94. PMID 6999010 DOI: 10.1210/Jcem-51-5-988  0.364
1980 Tager H, Thomas N, Assoian R, Rubenstein A, Saekow M, Olefsky J, Kaiser ET. Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. Proceedings of the National Academy of Sciences of the United States of America. 77: 3181-5. PMID 6997872 DOI: 10.1073/Pnas.77.6.3181  0.759
1980 Olefsky JM, Saekow M, Tager H, Rubenstein AH. Characterization of a mutant human insulin species Journal of Biological Chemistry. 255: 6098-6105. PMID 6993466  0.676
1980 Brennan MD, Service FJ, Carpenter AM, Rubenstein AH, Edis AJ. Diagnosis of pancreatic islet hyperplasia causing hypoglycemia in a patient with portacaval anastomosis The American Journal of Medicine. 68: 941-948. PMID 6992572 DOI: 10.1016/0002-9343(80)90228-4  0.467
1980 Assoian RK, Blix PM, Rubenstein AH, Tager HS. Iodotyrosylation of peptides using tertiary-Butyloxycarbonyl-L-[125I]iodotyrosine N-hydroxysuccinimide ester. Analytical Biochemistry. 103: 70-6. PMID 6990829 DOI: 10.1016/0003-2697(80)90238-9  0.568
1980 Steiner DF, Patzelt C, Chan SJ, Quinn PS, Tager HS, Nielsen D, Lernmark A, Noyes BE, Agarwal KL, Gabbay KH, Rubenstein AH. Formation of biologically active peptides. Proceedings of the Royal Society of London. Series B, Biological Sciences. 210: 45-59. PMID 6107930 DOI: 10.1098/Rspb.1980.0117  0.655
1979 Baldwin D, Winston E, Hoshizaki RJ, Garland JT, Baldwin D, Holcomb HH, Flier JS, Rubenstein A. Insulin-resistant diabetes with insulin receptor autoantibodies in a male patient without acanghosis nigricans. Diabetes Care. 2: 275-7. PMID 510120 DOI: 10.2337/Diacare.2.3.275  0.595
1979 Reynolds C, Tronsgard N, Gibbons E, Blix PM, Rubenstein AH. Gastric inhibitory polypeptide response to hyper- and hypoglycemia in insulin-dependent diabetics Journal of Clinical Endocrinology and Metabolism. 49: 255-261. PMID 457845 DOI: 10.1210/Jcem-49-2-255  0.565
1979 Goldman J, Baldwin D, Rubenstein AH, Klink DD, Blackard WG, Fisher LK, Roe TF, Schnure JJ. Characterization of circulating insulin and proinsulin-binding antibodies in autoimmune hypoglycemia Journal of Clinical Investigation. 63: 1050-1059. PMID 447827 DOI: 10.1172/Jci109374  0.567
1979 Gonen B, Goldman J, Baldwin D, Goldberg RB, Ryan WG, Blix PM, Schanzlin D, Fritz KJ, Rubenstein AH. Metabolic control in diabetic patients. Effect of insulin-secretory reserve (measured by plasma c-peptide levels) and circulating insulin antibodies Diabetes. 28: 749-753. PMID 446933 DOI: 10.2337/Diab.28.8.749  0.606
1979 Dumler F, Cortes P, Levin NW, Spargo BH, Rubenstein AH, Verghese CP. Effects of orotate administration on the normal rat kidney. Similarity to changes observed in diabetes mellitus Diabetes. 28: 680-685. PMID 446921 DOI: 10.2337/Diab.28.7.680  0.347
1979 Savage PJ, Flock EV, Mako ME, Blix PM, Rubenstein AH, Bennett PH. C-peptide and insulin secretion in Pima Indians and Caucasians: Constant fractional hepatic extraction over a wide range of insulin concentration and in obesity Journal of Clinical Endocrinology and Metabolism. 48: 594-598. PMID 429504 DOI: 10.1210/Jcem-48-4-594  0.629
1979 Schwartz SS, Horwitz DL, Zehfus B, Langer B, Moossa AR, Ribeiro G, Kaplan E, Rubenstein AH. Use of a glucose controlled insulin infusion system (artificial beta cell) to control diabetes during surgery Diabetologia. 16: 157-164. PMID 428685 DOI: 10.1007/BF01219792  0.376
1979 Tager H, Given B, Baldwin D, Mako M, Markese J, Rubenstein A, Olefsky J, Kobayashi M, Kolterman O, Poucher R. A structurally abnormal insulin causing human diabetes Nature. 281: 122-125. PMID 381941 DOI: 10.1038/281122A0  0.742
1979 Nelson RL, Baldus WP, Rubenstein AH, Go VL, Service FJ. Pancreatic α-cell function in diabetic hemochromatotic subjects Journal of Clinical Endocrinology and Metabolism. 49: 412-416. PMID 381322 DOI: 10.1210/Jcem-49-3-412  0.543
1979 Horwitz DL, Rubenstein AH. Evaluation of insulin secretory capacity in diabetes mellitus Human Pathology. 10: 257-266. PMID 381153 DOI: 10.1016/S0046-8177(79)80023-4  0.662
1979 Krejs GJ, Orci L, Conlon JM, Ravazzola M, Davis GR, Raskin P, Collins SM, McCarthy DM, Baetens D, Rubenstein A, Aldor TA, Unger RH. Somatostatinoma syndrome. Biochemical, morphologic and clinical features. The New England Journal of Medicine. 301: 285-92. PMID 377080 DOI: 10.1056/Nejm197908093010601  0.36
1979 Gabbay KH, Bergenstal RM, Wolff J, Mako ME, Rubenstein AH. Familial hyperproinsulinemia: Partial characterization of circulating proinsulin-like material Proceedings of the National Academy of Sciences of the United States of America. 76: 2881-2885. PMID 288074 DOI: 10.1073/Pnas.76.6.2881  0.481
1979 Kaplan EL, Rubenstein AH, Evans R, Lee CH, Klementschitsch P. Calcium infusion. A new provocative test for insulinomas Annals of Surgery. 190: 501-507. PMID 226013  0.343
1979 Lernmark A, Kanatsuna T, Rubenstein AH, Steiner DF. Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface Advances in Experimental Medicine and Biology. 119: 157-163. PMID 91312 DOI: 10.1007/978-1-4615-9110-8_23  0.311
1978 Phelps RL, Freinkel N, Rubenstein AH, Kuzuya H, Metzger BE, Boehm JJ, Mølsted-Pedersen L. Carbohydrate metabolism in pregnancy. XV. Plasma C peptide during intravenous glucose tolerance in neonates from normal and insulin treated diabetic mothers Journal of Clinical Endocrinology and Metabolism. 46: 61-68. PMID 752025  0.463
1978 Faber OK, Hagen C, Binder C, Markussen J, Naithani VK, Blix PM, Kuzuya H, Horwitz DL, Rubenstein AH, Rossing N. Kinetics of human connecting peptide in normal and diabetic subjects Journal of Clinical Investigation. 62: 197-203. PMID 659633 DOI: 10.1172/Jci109106  0.484
1978 Goldman J, Baldwin D, Pugh W, Rubenstein AH. Equilibrium binding assay and kinetic characterization of insulin antibodies Diabetes. 27: 653-660. PMID 658611 DOI: 10.2337/Diab.27.6.653  0.535
1978 Kuku SF, Jaspan JB, Emmanouel DS, Katz AI, Rubenstein AH. Plasma glucagon, insulin and glucose responses to intravenous arginine infusion in the rat Hormone and Metabolic Research. 10: 99-100. PMID 649048  0.445
1978 Liljenquist JE, Horwitz DL, Jennings AS, Chiasson JL, Keller U, Rubenstein AH. Inhibition of insulin secretion by exogenous insulin in normal man as demonstrated by C-peptide assay Diabetes. 27: 563-570. PMID 648746  0.588
1978 Anderson JH, Blackard WG, Goldman J, Rubenstein AH. Diabetes and hypoglycemia due to insulin antibodies The American Journal of Medicine. 64: 868-873. PMID 645751 DOI: 10.1016/0002-9343(78)90530-2  0.497
1978 Starr JI, Mako ME, Juhn D, Rubenstein AH. Measurement of serum proinsulin-like material: cross-reactivity of porcine and human proinsulin in the insulin radioimmunoassay Journal of Laboratory and Clinical Medicine. 91: 583-692. PMID 641392  0.516
1978 Horwitz DL, Rubenstein AH, Mako ME, Cruz A, Blix PM. C-peptide in conditions other than diabetes mellitus Diabetes. 27: 267-271. PMID 631444 DOI: 10.2337/Diab.27.1.S267  0.65
1978 Rabkin R, Ross BD, Mako ME, Rubenstein AH. The handling of insulin, proinsulin, and C-peptide by the isolated rat kidney Diabetes. 27: 192-196. PMID 631440 DOI: 10.2337/Diab.27.1.S192  0.614
1978 Kuzuya H, Chance RE, Steiner DF, Rubenstein AH. On the preparation and characterization of standard materials for natural human proinsulin and C-peptide Diabetes. 27: 161-169. PMID 631438 DOI: 10.2337/Diab.27.1.S161  0.455
1978 Service FJ, Nelson RL, Rubenstein AH, Go VLW. Direct effect of insulin on secretion of insulin, glucagon, gastric inhibitory polypeptide, and gastrin during maintenance of normoglycemia Journal of Clinical Endocrinology and Metabolism. 47: 488-493. PMID 400722 DOI: 10.1210/Jcem-47-3-488  0.621
1978 Schwartz SS, Zeidler A, Moossa AR, Kuku SF, Rubenstein AH. A prospective study of glucose tolerance, insulin, C-peptide, and glucagon responses in patients with pancreatic carcinoma The American Journal of Digestive Diseases. 23: 1107-1114. PMID 367155 DOI: 10.1007/BF01072886  0.434
1978 Kobayashi M, Olefsky JM, Elders J, Mako ME, Given BD, Schedwie HK, Fiser RH, Hintz RL, Horner JA, Rubenstein AH. Insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism Proceedings of the National Academy of Sciences of the United States of America. 75: 3469-3473. PMID 277948 DOI: 10.1073/Pnas.75.7.3469  0.54
1978 Koerker DJ, Goodner CJ, Walike Hansen B, Brown AC, Rubenstein AH. Synchronous, sustained oscillation of C-peptide and insulin in the plasma of fasting monkeys Endocrinology. 102: 1649-1652. PMID 105880  0.545
1978 Horwitz DL, Rubenstein AH, Steiner DF. Proinsulin and C-peptide in diabetes Medical Clinics of North America. 62: 723-733. PMID 98676 DOI: 10.1016/S0025-7125(16)31768-0  0.38
1977 Jaspan JB, Mako ME, Kuzuya H, Blix PM, Horwitz DL, Rubenstein AH. Abnormalities in circulating beta cell peptides in chronic renal failure: comparison of C-peptide, proinsulin and insulin. The Journal of Clinical Endocrinology and Metabolism. 45: 441-6. PMID 903396 DOI: 10.1210/JCEM-45-3-441  0.39
1977 Jaspan JB, Huen AH, Morley CG, Moossa AR, Rubenstein AH. The Role of the Liver in Glucagon Metabolism Journal of Clinical Investigation. 60: 421-428. PMID 874100 DOI: 10.1172/Jci108791  0.301
1977 Grajwer LA, Pildes RS, Horwitz DL, Rubenstein AH. Control of juvenile diabetes mellitus and its relationship to endogenous insulin secretion as measured by C-peptide immunoreactivity. The Journal of Pediatrics. 90: 42-8. PMID 830892 DOI: 10.1016/S0022-3476(77)80762-2  0.448
1977 Reynolds C, Molnar GD, Horwitz DL, Rubenstein AH, Taylor WF, Jiang NS. Abnormalities of endogenous glucagon and insulin in unstable diabetes. Diabetes. 26: 36-45. PMID 830563 DOI: 10.2337/diab.26.1.36  0.438
1977 Kuzuya H, Blix PM, Horwitz DL, Steiner DF, Rubenstein AH. Determination of free and total insulin and C-peptide in insulin-treated diabetics. Diabetes. 26: 22-9. PMID 830562 DOI: 10.2337/Diab.26.1.22  0.661
1977 Mako ME, Starr JI, Rubenstein AH. Circulating Proinsulin in Patients with Maturity Onset Diabetes The American Journal of Medicine. 63: 865-869. PMID 343587 DOI: 10.1016/0002-9343(77)90538-1  0.438
1977 Horwitz DL, Rubenstein AH, Katz AI. Quantitation of Human Pancreatic Beta-cell Function by Immunoassay of C-Peptide in Urine Diabetes. 26: 30-35. PMID 318625 DOI: 10.2337/Diab.26.1.30  0.491
1977 Rubenstein AH, Steiner DF, Horwitz DL, Mako ME, Block MB, Starr JI, Kuzuya H, Melani F. Clinical significance of circulating proinsulin and C-peptide. Recent Progress in Hormone Research. 33: 435-75. PMID 198859 DOI: 10.1016/B978-0-12-571133-3.50017-9  0.573
1977 Scarlett JA, Mako ME, Rubenstein AH, Blix PM, Goldman J, Horwitz DL, Tager H, Jaspan JB, Stjernholm MR, Olefsky JM. Factitious hypoglycemia. Diagnosis by measurement of serum C-peptide immunoreactivity and insulin-binding antibodies New England Journal of Medicine. 297: 1029-1032. PMID 198659 DOI: 10.1056/Nejm197711102971903  0.771
1977 Rubenstein AH, Kuzuya H, Horwitz DL. Clinical significance of circulating C-peptide in diabetes mellitus and hypoglycemic disorders. Jama Internal Medicine. 137: 625-632. DOI: 10.1001/Archinte.1977.03630170047014  0.598
1976 Kuku SF, Zeidler A, Emmanouel DS, Katz AI, Rubenstein AH. Heterogeneity Of Plasma Glucagon: Patterns In Patients With Chronic Renal Failure And Diabetes. The Journal of Clinical Endocrinology and Metabolism. 42: 173-176. PMID 1249185 DOI: 10.1210/Jcem-42-1-173  0.321
1976 Horwitz DL, Rubenstein AH, Reynolds C, Molnar GD, Yanaihara N. Prolonged suppression of insulin release by insulin-induced hypoglycemia: demonstration by C-peptide assay. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. 7: 449-52. PMID 1213648 DOI: 10.1055/S-0028-1093701  0.586
1976 Sandler R, Horwitz DL, Rubenstein AH, Kuzuya H. Hypoglycemia and endogenous hyperinsulinism complicating diabetes mellitus. Application of the C-peptide assay to diagnosis and therapy. The American Journal of Medicine. 59: 730-6. PMID 1200040 DOI: 10.1016/0002-9343(75)90234-X  0.386
1976 Lewis SB, Wallin JD, Kuzuya H, Murray WK, Coustan DR, Daane TA, Rubenstein AH. Circadian variation of serum glucose, C-peptide immunoreactivity and free insulin normal and insulin-treated diabetic pregnant subjects. Diabetologia. 12: 343-50. PMID 964510 DOI: 10.1007/BF00420978  0.488
1976 Kuku SF, Jaspan JB, Emmanouel DS, Zeidler A, Katz AI, Rubenstein AH. Heterogeneity of plasma glucagon. Circulating components in normal subjects and patients with chronic renal failure. Journal of Clinical Investigation. 58: 742-750. PMID 956399 DOI: 10.1172/Jci108521  0.383
1976 Lernmark A, Chan SJ, Choy R, Nathans A, Carroll R, Tager HS, Rubenstein AH, Swift HH, Steiner DF. Biosynthesis of insulin and glucagon: a view of the current state of the art. Ciba Foundation Symposium. 41: 7-30. PMID 780079  0.747
1976 Rayfield EJ, Pulini M, Golub A, Rubenstein AH, Horwitz DL. Nonautonomous function of a pancreatic insulinoma. The Journal of Clinical Endocrinology and Metabolism. 43: 1307-11. PMID 187613 DOI: 10.1210/Jcem-43-6-1307  0.556
1976 Alsever RN, Stjernholm MR, Sussman KE, Mako ME, Rubenstein AH. Clinical correlations of serum proinsulin-like material in islet cell tumours. Diabetologia. 12: 527-30. PMID 185114 DOI: 10.1007/BF01219519  0.354
1976 Horwitz DL, Kuzuya H, Rubenstein AH. Circulating serum C-peptide. A brief review of diagnostic implications. The New England Journal of Medicine. 295: 207-209. PMID 179006 DOI: 10.1056/Nejm197607222950407  0.617
1975 Yanaihara N, Sakura N, Yanaihara C, Hashimoto T, Rubenstein AH, Steiner DF. Syntheses and immunological evaluation of bovine proinsulin C-peptide analogues. Nature. 258: 365-366. PMID 1238906 DOI: 10.1038/258365A0  0.37
1975 Katz AI, Lindheimer MD, Mako ME, Rubenstein AH. Peripheral metabolism of insulin, proinsulin, and C-peptide in the pregnant rat. Journal of Clinical Investigation. 56: 1608-1614. PMID 1202086 DOI: 10.1172/Jci108243  0.584
1975 Rosenbloom AL, Starr JI, Juhn D, Rubenstein AH. Serum Proinsulin in Children and Adolescents with Chemical Diabetes Diabetes. 24: 753-757. PMID 1158039 DOI: 10.2337/Diab.24.8.753  0.499
1975 Horwitz DL, Starr JI, Mako ME, Blackard WG, Rubenstein AH. Proinsulin, insulin, and C-peptide concentrations in human portal and peripheral blood. The Journal of Clinical Investigation. 55: 1278-83. PMID 1133173 DOI: 10.1172/JCI108047  0.571
1975 Couropmitree C, Freinkel N, Nagel TC, Horwitz DL, Rubenstein AH, Metzger B, Hahnel R. Plasma C peptide and diagnosis of factitious hyperinsulinism. Study of an insulin dependent diabetic patient with 'spontaneous' hypoglycemia Annals of Internal Medicine. 82: 201-204. PMID 1115442 DOI: 10.7326/0003-4819-82-2-201  0.581
1975 Phelps RL, Bergenstal R, Freinkel N, Rubenstein AH, Metzger BE, Mako M. Carbohydrate metabolism in pregnancy: XIII. Relationships between plasma insulin and proinsulin during late pregnancy in normal and diabetic subjects Journal of Clinical Endocrinology and Metabolism. 41: 1085-1091. PMID 1107346 DOI: 10.1210/JCEM-41-6-1085  0.476
1975 Rubenstein AH, Mako ME, Horwitz DL. Insulin and the kidney. Nephron. 15: 306-26. PMID 1101090 DOI: 10.1159/000180518  0.367
1975 Constan L, Mako M, Juhn D, Rubenstein AH. The excretion of proinsulin and insulin in urine. Diabetologia. 11: 119-23. PMID 168106 DOI: 10.1007/BF00429834  0.534
1975 Alsever RN, Roberts JP, Gerber JG, Mako ME, Rubenstein AH. Insulinoma with low circulating insulin levels: the diagnostic value of proinsulin measurements. Annals of Internal Medicine. 82: 347-350. PMID 163611 DOI: 10.7326/0003-4819-82-3-347  0.548
1975 Tager HS, Rubenstein AH, Steiner DF. [28] Methods for the assessment of peptide precursors. Studies on insulin biosynthesis Methods in Enzymology. 37: 326-345. DOI: 10.1016/S0076-6879(75)37030-4  0.72
1974 Fink G, Cresto JC, Gutman RA, Lavine RL, Rubenstein AH, Recant L. Plasma proinsulin like material in insulin treated diabetics Hormone and Metabolic Research. 6: 439-443. PMID 4452543 DOI: 10.1055/S-0028-1093819  0.489
1974 Starr JI, Rubenstein AH. Metabolism of endogenous proinsulin and insulin in man. The Journal of Clinical Endocrinology and Metabolism. 38: 305-8. PMID 4360023 DOI: 10.1210/JCEM-38-2-305  0.453
1973 Ginsberg S, Block MB, Mako ME, Rubenstein AH. Serum insulin levels following administration of exogenous insulin. The Journal of Clinical Endocrinology and Metabolism. 36: 1175-9. PMID 4706205 DOI: 10.1210/JCEM-36-6-1175  0.525
1973 Katz AI, Rubenstein AH. Metabolism of Proinsulin, Insulin, and C-Peptide in the Rat Journal of Clinical Investigation. 52: 1113-1121. PMID 4700486 DOI: 10.1172/Jci107277  0.495
1973 Rabkin R, Rubenstein AH, Colwell JA. Glomerular filtration and proximal tubular absorption of insulin 125 I. The American Journal of Physiology. 223: 1093-6. PMID 4654343 DOI: 10.1152/AJPLEGACY.1972.223.5.1093  0.48
1973 Borensztajn J, Samols DR, Rubenstein AH. Effects of insulin on lipoprotein lipase activity in the rat heart and adipose tissue. The American Journal of Physiology. 223: 1271-5. PMID 4641617 DOI: 10.1152/AJPLEGACY.1972.223.6.1271  0.349
1973 Block MB, Rosenfield RL, Mako ME, Steiner DF, Rubenstein AH. Sequential changes in beta-cell function in insulin-treated diabetic patients assessed by C-peptide immunoreactivity. The New England Journal of Medicine. 288: 1144-8. PMID 4633551 DOI: 10.1056/Nejm197305312882202  0.467
1972 Rubenstein AH, Pottenger LA, Mako M, Getz GS, Steiner DF. The metabolism of proinsulin and insulin by the liver. The Journal of Clinical Investigation. 51: 912-21. PMID 5014618 DOI: 10.1172/Jci106886  0.613
1972 Kemmler W, Peterson JD, Rubenstein AH, Steiner DF. On the biosynthesis, intracellular transport and mechanism of conversion of proinsulin to insulin and C-peptide Diabetes. 21: 572-581. PMID 4626567 DOI: 10.2337/Diab.21.2.S572  0.59
1972 Block MB, Mako ME, Steiner DF, Rubenstein AH. Diabetic ketoacidosis: evidence for C-peptide and proinsulin secretion following recovery. The Journal of Clinical Endocrinology and Metabolism. 35: 402-6. PMID 4626271 DOI: 10.1210/Jcem-35-3-402  0.554
1972 Rubenstein AH, Block MB, Starr J, Melani F, Steiner DF. Proinsulin and C-peptide in blood. Diabetes. 21: 661-72. PMID 4341001 DOI: 10.2337/Diab.21.2.S661  0.649
1972 Block MB, Mako ME, Steiner DF, Rubenstein AH. Circulating C-peptide immunoreactivity. Studies in normals and diabetic patients. Diabetes. 21: 1013-26. PMID 4116300 DOI: 10.2337/Diab.21.10.1013  0.518
1971 Lowy C, Wright AD, Fraser TR, Rubenstein AH, Spitz I. Urine excretion of insulin and growth hormone in subjects with renal failure. Acta Endocrinologica. 67: 85-96. PMID 5108349 DOI: 10.1530/ACTA.0.0670085  0.326
1970 Rubenstein AH, Zwi S, Miller K. Insulin and the lung. Diabetologia. 4: 236-8. PMID 5738363 DOI: 10.1007/BF00430101  0.386
1970 Rubenstein AH, Lowy C, Fraser TR. Radioimmunoassay of insulin in urine. Diabetologia. 3: 453-9. PMID 5620804 DOI: 10.1007/BF01228082  0.541
1970 Melani F, Rubenstein AH, Steiner DF. Human serum proinsulin. The Journal of Clinical Investigation. 49: 497-507. PMID 5461203 DOI: 10.1172/Jci106259  0.528
1970 Spitz IM, Rubenstein AH, Bersohn I, Van AS M. The blood sugar and serum insulin response to intravenous glucagon in chronic renal failure. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 134: 142-5. PMID 5423495 DOI: 10.3181/00379727-134-34746  0.334
1970 Melani F, Rubenstein AH, Oyer PE, Steiner DF. Identification of proinsulin and C-peptide in human serum by a specific immunoassay. Proceedings of the National Academy of Sciences of the United States of America. 67: 148-55. PMID 4318774 DOI: 10.1073/Pnas.67.1.148  0.581
1970 Melani F, Ryan WG, Rubenstein AH, Steiner DF. Proinsulin secretion by a pancreatic beta-cell adenoma. Proinsulin and C-peptide secretion. The New England Journal of Medicine. 283: 713-9. PMID 4318337 DOI: 10.1056/Nejm197010012831401  0.597
1970 Steiner DF, Clark JL, Nolan C, Rubenstein AH, Margoliash E, Aten B, Oyer PE. Proinsulin and the biosynthesis of insulin. Recent Progress in Hormone Research. 25: 207-82. PMID 4311938 DOI: 10.1016/b978-0-12-571125-8.50008-9  0.533
1970 Rubenstein AH, Steiner DF. Proinsulin: The Single Chain Precursor of Insulin Medical Clinics of North America. 54: 191-199. DOI: 10.1016/S0025-7125(16)32687-6  0.481
1970 Block MB, Rubenstein AH. Spontaneous Hypoglycemia in Diabetic Patients With Renal Insufficiency Jama. 213: 1863-1866. DOI: 10.1001/Jama.1970.03170370047008  0.468
1969 Rubenstein AH, Steiner DF, Cho S, Lawrence AM, Kirsteins L. Immunological properties of bovine proinsulin and related fractions Diabetes. 18: 598-605. PMID 5821058 DOI: 10.2337/Diab.18.9.598  0.645
1969 Rubenstein AH, Seftel HC, Miller K, Bersohn I, Wright AD. Metabolic response to oral glucose in healthy South African white, Indian, and African subjects. British Medical Journal. 1: 748-51. PMID 5769861 DOI: 10.1136/bmj.1.5646.748  0.41
1969 Steiner DF, Hallund O, Rubenstein A, Cho S, Bayliss C. Isolation and properties of proinsulin, intermediate forms, and other minor components from crystalline bovine insulin. Diabetes. 17: 725-36. PMID 5726253 DOI: 10.2337/Diab.17.12.725  0.616
1969 Rubenstein AH, Clark JL, Melani F, Steiner DF. Secretion of proinsulin C-Peptide by pancreatic β cells and its circulation in blood Nature. 224: 697-699. DOI: 10.1038/224697A0  0.468
1969 Rubenstein AH. The Significance of Immunoassayable Insulin in Urine Jama: the Journal of the American Medical Association. 209: 254. DOI: 10.1001/JAMA.1969.03160150040010  0.539
1968 Lopis S, Rubenstein AH, Wright AD. Measurements of serum growth hormone and insulin in gigantism Journal of Clinical Endocrinology and Metabolism. 28: 393-398. PMID 5642691 DOI: 10.1210/JCEM-28-3-393  0.416
1968 Rubenstein AH, Spitz I. Role of the kidney in insulin metabolism and excretion. Diabetes. 17: 161-9. PMID 4867026 DOI: 10.2337/diab.17.3.161  0.405
1968 Milunsky A, Lowy C, Rubenstein AH, Wright AD. Carbohydrate tolerance, growth hormone and insulin levels in mongolism. Developmental Medicine and Child Neurology. 10: 25-31. PMID 4230643 DOI: 10.1111/j.1469-8749.1968.tb02833.x  0.441
1967 Trayner IM, Welborn TA, Rubenstein AH, Fraser TR. Serum and urine insulin in late pregnancy and in a few pregnant latent diabetics. The Journal of Endocrinology. 37: 443-53. PMID 6022881 DOI: 10.1677/JOE.0.0370443  0.361
1967 Rubenstein AH, Lowy C, Welborn TA, Fraser TR. Urine insulin in normal subjects. Metabolism: Clinical and Experimental. 16: 234-44. PMID 6020732 DOI: 10.1016/0026-0495(67)90172-2  0.458
1966 Welborn TA, Rubenstein AH, Haslam R, Fraser R. Normal insulin response to glucose. Lancet (London, England). 1: 280-3. PMID 4158892 DOI: 10.1016/S0140-6736(66)90637-4  0.477
Low-probability matches (unlikely to be authored by this person)
1978 Kuzuya H, Blix PM, Horwitz DL, Rubenstein AH, Steiner DF, Faber OK, Binder C. Heterogeneity of circulating human C-peptide Diabetes. 27: 184-191. PMID 75814 DOI: 10.2337/Diab.27.1.S184  0.3
1978 Faber OK, Binder C, Markussen J, Heding LG, Naithani VK, Kuzuya H, Blix P, Horwitz DL, Rubenstein AH. Characterization of seven C-peptide antisera Diabetes. 27: 170-177. PMID 564799  0.295
1982 Ipp E, Dhorajiwala J, Pugh W, Moossa AR, Rubenstein AH. Effects of an enkephalin analog on pancreatic endocrine function and glucose homeostasis in normal and diabetic dogs. Endocrinology. 111: 2110-6. PMID 7140647 DOI: 10.1210/endo-111-6-2110  0.293
1983 Jackson RA, Blix PM, Matthews JA, Peters N, Pilkington TR, Rubenstein AH, Nabarro JD. Peripheral glucose uptake in young men with myocardial infarction Hormone and Metabolic Research. 15: 585-588. PMID 6363241  0.293
1977 Kuzuya H, Blix PM, Horwitz DL, Rubenstein AH, Steiner DF, Binder C, Faber OK. Heterogeneity of circulating C-peptide. The Journal of Clinical Endocrinology and Metabolism. 44: 952-62. PMID 558224 DOI: 10.1210/Jcem-44-5-952  0.292
1979 Gonen B, Rochman H, Rubenstein AH. Metabolic control in diabetic patients: Assessment by hemoglobin A1 values Metabolism. 28: 448-452. PMID 400565 DOI: 10.1016/0026-0495(79)90054-4  0.29
1986 Glauber HS, Revers RR, Henry R, Schmeiser L, Wallace P, Kolterman OG, Cohen RM, Rubenstein AH, Galloway JA, Frank BH. In vivo deactivation of proinsulin action on glucose disposal and hepatic glucose production in normal man Diabetes. 35: 311-317. PMID 3512341  0.288
1983 Jackson RA, Blix PM, Matthews JA, Morgan LM, Rubenstein AH, Nabarro JD. Comparison of peripheral glucose uptake after oral glucose loading and a mixed meal. Metabolism: Clinical and Experimental. 32: 706-10. PMID 6345991 DOI: 10.1016/0026-0495(83)90128-2  0.288
1979 Sosenko IR, Kitzmiller JL, Loo SW, Blix P, Rubenstein AH, Gabbay KH. The infant of the diabetic mother. Correlation of increased cord C-peptide levels with macrosomia and hypoglycemia New England Journal of Medicine. 301: 859-862. PMID 481527  0.285
1981 Lin CC, River P, Moawad AH, Lowensohn RI, Blix PM, Abraham M, Rubenstein AH. Prenatal assessment of fetal outcome by amniotic fluid C-peptide levels in pregnant diabetic women. American Journal of Obstetrics and Gynecology. 141: 671-6. PMID 7032297  0.285
1977 Gonen B, Rubenstein A, Rochman H, Tanega SP, Horwitz DL. Haemoglobin A1: An indicator of the metabolic control of diabetic patients. Lancet (London, England). 2: 734-7. PMID 71541 DOI: 10.1016/S0140-6736(77)90237-9  0.282
1969 Clark JL, Cho S, Rubenstein AH, Steiner DF. Isolation of a proinsulin connecting peptide fragment (C-peptide) from bovine and human pancreas. Biochemical and Biophysical Research Communications. 35: 456-61. PMID 5788502 DOI: 10.1016/0006-291X(69)90367-2  0.281
1988 Sanke T, Bell GI, Sample C, Rubenstein AH, Steiner DF. An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing Journal of Biological Chemistry. 263: 17243-17246. PMID 3053705  0.277
1970 Rubenstein AH, Welbourne WP, Mako M, Melani F, Steiner DF. Comparative immunology of bovine, porcine and human proinsulins and C-peptides. Diabetes. 19: 546-53. PMID 5449148 DOI: 10.2337/diab.19.8.546  0.275
1978 Lernmark A, Freedman ZR, Hofmann C, Rubenstein AH, Steiner DF, Jackson RL, Winter RJ, Traisman HS. Islet-cell-surface antibodies in juvenile diabetes mellitus New England Journal of Medicine. 299: 375-380. PMID 353557 DOI: 10.1056/Nejm197808242990802  0.273
1971 Steiner DF, Cho S, Oyer PE, Terris S, Peterson JD, Rubenstein AH. Isolation and Characterization of Proinsulin C-Peptide from Bovine Pancreas Journal of Biological Chemistry. 246: 1365-1374. DOI: 10.1016/s0021-9258(19)76983-x  0.272
1980 Cortes P, Levin NW, Dumler F, Rubenstein AH, Verghese CP, Venkatachalam KK. Uridine triphosphate and RNA synthesis during diabetes-induced renal growth. The American Journal of Physiology. 238: E349-57. PMID 6155075 DOI: 10.1152/Ajpendo.1980.238.4.E349  0.271
1979 Gonen B, Rubenstein AH. Glycosylated hemoglobins in diabetes: A reappraisal Diabetes Care. 2: 451-452. PMID 12085580 DOI: 10.2337/Diacare.2.5.451  0.267
1990 Wojcikowski C, Blackman J, Ostrega D, Lewis G, Galloway J, Rubenstein AH, Polonsky KS. Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects Metabolism. 39: 827-832. PMID 2198434 DOI: 10.1016/0026-0495(90)90127-X  0.261
1993 Oohashi H, Ohgawara H, Nanjo K, Tasaka Y, Cao QP, Shu Jin Chan, Rubenstein AH, Steiner DF, Omori Y. Familial hyperproinsulinemia associated with NIDDM: A case study Diabetes Care. 16: 1340-1346. PMID 8269791 DOI: 10.2337/Diacare.16.10.1340  0.252
1986 Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Preferential suppression of hepatic glucose production by human proinsulin in the dog Surgical Forum. 37: 121-123.  0.251
1986 Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Preferential suppression of hepatic glucose production by human proinsulin in the dog Surgical Forum. 37: 121-123.  0.251
1973 Block MB, Berk JE, Fridhandler LS, Steiner DF, Rubenstein AH. Diabetic ketoacidosis associated with mumps virus infection. Occurrence in a patient with macroamylasemia. Annals of Internal Medicine. 78: 663-7. PMID 4197153 DOI: 10.7326/0003-4819-78-5-663  0.249
1983 Madsen OD, Cohen RM, Fitch FW, Rubenstein AH, Steiner DF. The production and characterization of monoclonal antibodies specific for human proinsulin using a sensitive microdot assay procedure. Endocrinology. 113: 2135-44. PMID 6196183 DOI: 10.1210/Endo-113-6-2135  0.249
1984 Ipp E, Garberoglio C, Richter H, Moossa AR, Rubenstein AH. Naloxone decreases centrally induced hyperglycemia in dogs. Evidence for an opioid role in glucose homeostasis Diabetes. 33: 619-621. PMID 6734943  0.248
1988 Casper RC, Pandy GN, Jaspan JB, Rubenstein AH. Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls Biological Psychiatry. 24: 663-674. PMID 3048427 DOI: 10.1016/0006-3223(88)90140-0  0.247
2015 Ducat L, Rubenstein A, Philipson LH, Anderson BJ. A review of the mental health issues of diabetes conference. Diabetes Care. 38: 333-8. PMID 25614689 DOI: 10.2337/Dc14-1383  0.246
1986 Licinio-Paixao J, Polonsky KS, Given BD, Pugh W, Ostrega D, Frank BF, Rubenstein AH. Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide Journal of Clinical Endocrinology and Metabolism. 63: 401-403. PMID 3722329  0.246
1988 Bergenstal RM, Morse P, Rubenstein AH, Bending JJ, Bilous RW, Keen H, Pickup JC, Viberti GC, Gosh G, Kohner EM, Lawson PM, Rizza RA, Service FJ, Trautmann JC, Canny CCB, et al. Diabetic retinopathy after two years of intensified insulin treatment. Follow-up of the Kroc Collaborative Study Journal of the American Medical Association. 260: 37-41. PMID 2898025 DOI: 10.1001/jama.1988.03410010045032  0.246
1997 Steiner DF, Rubenstein AH. Proinsulin C-peptide-biological activity? Science. 277: 531-532. PMID 9254422 DOI: 10.1126/science.277.5325.531  0.245
1982 Jaspan JB, Wollman RL, Bernstein L, Rubenstein AH. Hypoglycemic peripheral neuropathy in association with insulinoma: implication of glucopenia rather than hyperinsulinism. Case report and literature review. Medicine. 61: 33-44. PMID 6276647 DOI: 10.1097/00005792-198201000-00004  0.243
1977 Jaspan JB, Rubenstein AH. Circulating Glucagon Plasma Profiles and Metabolism in Health and Disease Diabetes. 26: 887-904. PMID 330295 DOI: 10.2337/Diab.26.9.887  0.242
1979 Rubenstein AH, Gonen B. Clinical significance of C-peptide Advances in Experimental Medicine and Biology. 124: 15-28. PMID 506831  0.241
1987 Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Selective suppression of hepatic glucose output by human proinsulin in the dog American Journal of Physiology - Endocrinology and Metabolism. 252: 15/2. PMID 2881485  0.238
2017 Fajgenbaum DC, Shilling D, Partridge HL, Pierson SK, Ruth JR, Nabel CS, Stone K, Chaturvedi V, Jordan MB, Cohen AD, Krymskaya V, Rubenstein AH, Rhee Fv, Uldrick TS. Prolonged Remission Achieved in a Relapsing Idiopathic Multicentric Castleman Disease Patient with a Novel, Targeted Treatment Approach Blood. 130: 3593-3593. DOI: 10.1182/Blood.V130.Suppl_1.3593.3593  0.234
1982 Jackson RA, Blix PM, Matthews JA, Hamling JB, Din BM, Brown DC, Belin J, Rubenstein AH, Nabarro JD. Influence of ageing on glucose homeostasis. The Journal of Clinical Endocrinology and Metabolism. 55: 840-8. PMID 6749877 DOI: 10.1210/jcem-55-5-840  0.234
1986 Hägglöf B, Rabinovitch A, Mackay P, Huen A, Rubenstein AH, Marner B, Nerup J, Lernmark A. Islet cell and other organ-specific autoantibodies in healthy first-degree relatives to insulin-dependent. Acta Paediatrica Scandinavica. 75: 611-8. PMID 3489346 DOI: 10.1111/J.1651-2227.1986.Tb10260.X  0.23
1986 Hägglöf B, Rabinovitch A, Mackay P, Huen A, Rubenstein AH, Marner B, Nerup J, Lernmark A. Islet cell and other organ-specific autoantibodies in healthy first-degree relatives to insulin-dependent. Acta Paediatrica Scandinavica. 75: 611-8. PMID 3489346 DOI: 10.1111/J.1651-2227.1986.Tb10260.X  0.23
1988 Carroll RJ, Hammer RE, Chan SJ, Swift HH, Rubenstein AH, Steiner DF. A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway. Proceedings of the National Academy of Sciences of the United States of America. 85: 8943-7. PMID 3057496 DOI: 10.1073/Pnas.85.23.8943  0.23
1988 Carroll RJ, Hammer RE, Chan SJ, Swift HH, Rubenstein AH, Steiner DF. A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway. Proceedings of the National Academy of Sciences of the United States of America. 85: 8943-7. PMID 3057496 DOI: 10.1073/Pnas.85.23.8943  0.23
2014 Fajgenbaum DC, Liu A, Ruth J, Nabel C, Finkelman B, Kurzrock R, van Rhee F, Rubenstein A. HHV-8-Negative, Idiopathic Multicentric Castleman Disease (iMCD): A Description of Clinical Features and Therapeutic Options through a Systematic Literature Review Blood. 124: 4861-4861. DOI: 10.1182/Blood.V124.21.4861.4861  0.226
1984 Herold KC, Huen A, Gould L, Traisman H, Rubenstein AH. Alterations in lymphocyte subpopulations in type 1 (insulin-dependent) diabetes mellitus: exploration of possible mechanisms and relationships to autoimmune phenomena Diabetologia. 27: 102-105. PMID 6237011 DOI: 10.1007/BF00275660  0.224
1976 Gabbay KH, DeLuca K, Fisher JN, Mako ME, Rubenstein AH. Familial hyperproinsulinemia. An autosomal dominant defect. The New England Journal of Medicine. 294: 911-5. PMID 815812 DOI: 10.1056/NEJM197604222941701  0.223
1988 Sanke T, Bell GI, Sample C, Rubenstein AH, Steiner DF. An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing Journal of Biological Chemistry. 263: 17243-17246. PMID 3053705  0.222
1968 Wright AD, Lowy C, Fraser TR, Spitz IM, Rubenstein AH, Bersohn I. Serum-growth hormone and glucose intolerance in renal failure. Lancet (London, England). 2: 798-801. PMID 4175603 DOI: 10.1016/S0140-6736(68)92456-2  0.22
1982 Blix PM, Boddie-Willis C, Landau RL, Rochman H, Rubenstein AH. Urinary C-peptide: an indicator of beta-cell secretion under different metabolic conditions. The Journal of Clinical Endocrinology and Metabolism. 54: 574-80. PMID 7035485 DOI: 10.1210/jcem-54-3-574  0.22
1982 Ipp E, Piran U, Richter H, Garberoglio C, Moossa A, Rubenstein AH. Central control of peripheral circulating somatostatin in dogs: effect of 2-deoxyglucose. The American Journal of Physiology. 243: E213-6. PMID 6126123  0.219
2012 Rubenstein AH. A fortunate life in academic medicine Journal of Clinical Investigation. 122: 4288-4292. PMID 23114609 DOI: 10.1172/Jci66850  0.216
2016 Liu AY, Nabel CS, Finkelman BS, Ruth JR, Kurzrock R, van Rhee F, Krymskaya VP, Kelleher D, Rubenstein AH, Fajgenbaum DC. Idiopathic multicentric Castleman's disease: a systematic literature review. The Lancet. Haematology. 3: e163-75. PMID 27063975 DOI: 10.1016/S2352-3026(16)00006-5  0.211
2019 Fajgenbaum DC, Langan RA, Sada Japp A, Partridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, ... ... Rubenstein A, et al. Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease. The Journal of Clinical Investigation. 130. PMID 31408438 DOI: 10.1172/Jci126091  0.211
1964 GOLDIN AR, RUBENSTEIN AH, BRADLOW BA, ELLIOTT GA. MALATHION POISONING WITH SPECIAL REFERENCE TO THE EFFECT OF CHOLINESTERASE INHIBITION ON ERYTHROCYTE SURVIVAL. The New England Journal of Medicine. 271: 1289-93. PMID 14214635 DOI: 10.1056/Nejm196412172712504  0.211
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Patient education and home blood glucose monitoring Geriatrics. 53: 60-67. PMID 9597980  0.208
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Patient education and home blood glucose monitoring Geriatrics. 53: 60-67. PMID 9597980  0.208
1977 Weir GC, Horton ES, Aoki TT, Slovik D, Jaspan J, Rubenstein AH. Secretion by glucagonomas of a possible glucagon precursor. The Journal of Clinical Investigation. 59: 325-30. PMID 833279 DOI: 10.1172/JCI108644  0.208
1978 Sosenko I, Kitzmiller J, Loo S, Gabbay K, Blix P, Rubenstein A, Taeusch HW. 895 FREE C-PEPTIDE LEVELS IN INFANTS OF DIABETIC MOTHERS: RELATIONSHIP TO HYPOGLYCEMIA, MACROSOMIA, AND HYALINE MEMBRANE DISEASE Pediatric Research. 12: 513-513. DOI: 10.1203/00006450-197804001-00900  0.208
2008 Phillips SE, Rubenstein AH. The changing relationships between academic health centers and their universities: a look at the University of Pennsylvania. Academic Medicine : Journal of the Association of American Medical Colleges. 83: 861-6. PMID 18728443 DOI: 10.1097/Acm.0B013E318181F19F  0.203
1981 Baekkeskov S, Kanatsuna T, Klareskog L, Nielsen DA, Peterson PA, Rubenstein AH, Steiner DF, Lernmark A. Expression of major histocompatibility antigens on pancreatic islet cells. Proceedings of the National Academy of Sciences of the United States of America. 78: 6456-60. PMID 7031653 DOI: 10.1073/Pnas.78.10.6456  0.198
2006 Crowley W, Courtney J, Jameson L, Pardes H, Moskowitz J, Orringer E, Rubenstein A, Wood A, Rettig R, Ausiello D, Brenner D, Collins F, Elias J, Greene W, Horowitz R, et al. The Clinical Research Forum and Association of American Physicians disagree with criticism of the NIH Roadmap. The Journal of Clinical Investigation. 116: 2058-9. PMID 16886049 DOI: 10.1172/Jci29557  0.198
1980 Mackie CR, Moossa AR, Go VL, Noble G, Sizemore G, Cooper MJ, Wood RA, Hall AW, Waldmann T, Gelder F, Rubenstein AH. Prospective evaluation of some candidate tumor markers in the diagnosis of pancreatic cancer. Digestive Diseases and Sciences. 25: 161-72. PMID 6989572 DOI: 10.1007/BF01308134  0.197
2015 Ennis J, Gillen D, Rubenstein A, Worcester E, Brecher ME, Asplin J, Coe F. Clinical decision support improves physician guideline adherence for laboratory monitoring of chronic kidney disease: a matched cohort study. Bmc Nephrology. 16: 163. PMID 26471846 DOI: 10.1186/S12882-015-0159-5  0.191
1980 Lernmark A, Kanatsuna T, Patzelt C, Diakoumis K, Carroll R, Rubenstein AH, Steiner DF. Antibodies directed against the pancreatic islet cell plasma membrane detection and specificity Diabetologia. 19: 445-451. PMID 7004963 DOI: 10.1007/Bf00281824  0.19
1992 Glickman R, Bennett JC, Nolan J, Stobo J, Rubenstein A, Terwilliger J. Activism in academic internal medicine Annals of Internal Medicine. 117: 259-260. PMID 1616222 DOI: 10.7326/0003-4819-117-3-259  0.189
1995 Steiner DF, Rubenstein AH. Tribute to Howard S. Tager Diabetes. 44: 137-139. DOI: 10.2337/Diab.44.1.137  0.188
2002 Bickel J, Wara D, Atkinson BF, Cohen LS, Dunn M, Hostler S, Johnson TR, Morahan P, Rubenstein AH, Sheldon GF, Stokes E. Increasing women's leadership in academic medicine: report of the AAMC Project Implementation Committee. Academic Medicine : Journal of the Association of American Medical Colleges. 77: 1043-61. PMID 12377686 DOI: 10.1097/00001888-200210000-00023  0.187
2016 Fajgenbaum DC, Ruth JR, Kelleher D, Rubenstein AH. The collaborative network approach: a new framework to accelerate Castleman's disease and other rare disease research. The Lancet. Haematology. 3: e150-2. PMID 27063967 DOI: 10.1016/S2352-3026(16)00007-7  0.186
2017 Pizzo PA, Lawley TJ, Rubenstein AH. Role of Leaders in Fostering Meaningful Collaborations Between Academic Medical Centers and Industry While Also Managing Individual and Institutional Conflicts of Interest. Jama. 317: 1729-1730. PMID 28464157 DOI: 10.1001/Jama.2017.2573  0.186
2007 Wasserstein AG, Brennan PJ, Rubenstein AH. Institutional leadership and faculty response: Fostering professionalism at the University of Pennsylvania School of Medicine Academic Medicine. 82: 1049-1056. PMID 17971690 DOI: 10.1097/Acm.0B013E31815763D2  0.184
2000 Levinson W, Rubenstein A. Integrating clinician-educators into Academic Medical Centers: challenges and potential solutions. Academic Medicine : Journal of the Association of American Medical Colleges. 75: 906-12. PMID 10995612 DOI: 10.1097/00001888-200009000-00012  0.181
2017 Grisso JA, Sammel MD, Rubenstein AH, Speck RM, Conant EF, Scott P, Tuton LW, Westring AF, Friedman S, Abbuhl SB. A Randomized Controlled Trial to Improve the Success of Women Assistant Professors. Journal of Women's Health (2002). PMID 28281865 DOI: 10.1089/Jwh.2016.6025  0.179
1999 Levinson W, Rubenstein A. Mission critical--integrating clinician-educators into academic medical centers. The New England Journal of Medicine. 341: 840-3. PMID 10477784 DOI: 10.1056/Nejm199909093411111  0.179
1993 Glickman RM, Claude Bennett J, Nolan JP, Stobo JD, Rubenstein A, Terwilliger J. Fostering a new relationship between departments of medicine and teaching hospitals Academic Medicine. 68: 276-277. PMID 8466609 DOI: 10.1097/00001888-199304000-00013  0.177
1984 Ipp E, Garberoglio C, Richter H, Moossa AR, Rubenstein AH. Naloxone decreases centrally induced hyperglycemia in dogs. Evidence for an opioid role in glucose homeostasis Diabetes. 33: 619-621. PMID 6734943  0.176
2015 Feldman AM, Runge MS, Garcia JG, Rubenstein AH. American medical education at a crossroads. Science Translational Medicine. 7: 285fs17. PMID 25925678 DOI: 10.1126/Scitranslmed.Aaa2039  0.173
1983 Jackson RA, Blix PM, Matthews JA, Peters N, Pilkington TR, Rubenstein AH, Nabarro JD. Peripheral glucose uptake in young men with myocardial infarction Hormone and Metabolic Research. 15: 585-588. PMID 6363241  0.161
2008 Iqbal N, Rubenstein AH. Does lowering of blood glucose improve cardiovascular morbidity and mortality? Clinical Journal of the American Society of Nephrology : Cjasn. 3: 163-7. PMID 18178783 DOI: 10.2215/CJN.05041107  0.148
2008 Iqbal N, Rubenstein AH. Does lowering of blood glucose improve cardiovascular morbidity and mortality? Clinical Journal of the American Society of Nephrology. 3: 163-167. DOI: 10.2215/CJN.05041107  0.148
1981 Ipp E, Rubenstein AH. Opioid peptides and stress hyperglycaemia. Lancet (London, England). 2: 1083. PMID 6107708 DOI: 10.1016/S0140-6736(80)92304-1  0.145
1983 Chen C, Glagov S, Mako M, Rochman H, Rubenstein AH. Post-mortem glycosylated hemoglobin (HbA1c): evidence for a history of diabetes mellitus. Annals of Clinical and Laboratory Science. 13: 407-10. PMID 6638930  0.139
1975 Feldman SA, Rubenstein AH, Taylor CB, Lewis LA, Mikkelson B. Carbohydrate and lipid metabolism in the Alaskan Arctic Eskimo. The American Journal of Clinical Nutrition. 28: 588-94. PMID 1130318 DOI: 10.1093/AJCN/28.6.588  0.137
1977 Emmanouel DS, Jaspan JB, Kuku SF, Rubenstein AH, Katz AI, Huen AH. Pathogenesis and characterization of hyperglucagonemia in the uremic rat. The Journal of Clinical Investigation. 58: 1266-72. PMID 993345 DOI: 10.1172/JCI108581  0.131
1975 Levin NW, Silveira E, Cortes P, Rubenstein AH. Relation of renal growth to diabetic glomerulosclerosis. Lancet (London, England). 1: 1120-1. PMID 49476 DOI: 10.1016/S0140-6736(75)92505-2  0.129
1979 Schwartz SS, Rich BH, Lucky AW, Straus FH, Gonen B, Wolfsdorf J, Thorp FW, Burrington JD, Madden JD, Rubenstein AH, Rosenfield RL. Familial nesidioblastosis: severe neonatal hypoglycemia in two families. The Journal of Pediatrics. 95: 44-53. PMID 383929 DOI: 10.1016/S0022-3476(79)80080-3  0.127
1978 Emmanouel DS, Jaspan JB, Rubenstein AH, Huen AH, Fink E, Katz AI. Glucagon metabolism in the rat. Contribution of the kidney to the metabolic clearance rate of the hormone Journal of Clinical Investigation. 62: 6-13. PMID 659638 DOI: 10.1172/JCI109114  0.123
1975 Wissler RW, Borensztajn J, Rubenstein A, Getz G, Vesselinovitch D. The effects of tolbutamide on the development of atherosclerosis in rhesus monkeys fed an average American table-prepared diet Advances in Experimental Medicine and Biology. 63: 379-380. PMID 812341 DOI: 10.1007/978-1-4684-3258-9_28  0.122
1966 Ireland JT, Patnaik BK, Duncan LJP, Jaksic Z, Jakob A, Lauper N, Flury R, Labhart A, Froesch ER, Jarrett RJ, Keen H, Track N, Jervell J, Vallance-Owen J, Bajaj JS, ... ... Rubenstein AH, et al. Second Annual Meeting of the European Association for the Study of Diabetes abstracts Diabetologia. 2: 202-228. DOI: 10.1007/BF01222072  0.122
1976 Morley CG, Kuku S, Rubenstein AH, Boyer JL. Serum hormone levels following partial hepatectomy in the rat. Biochemical and Biophysical Research Communications. 67: 653-61. PMID 1201045 DOI: 10.1016/0006-291X(75)90862-1  0.121
1977 Jaspan JB, Kuku SF, Locker JD, Huen A, Emmanouel DS, Katz AI, Rubenstein AH. Heterogeneity of plasma glucagon in man. Metabolism: Clinical and Experimental. 25: 1397-401. PMID 185495 DOI: 10.1016/S0026-0495(76)80150-3  0.115
1992 Herold KC, Rubenstein AH. New directions in the immunology of autoimmune diabetes Annals of Internal Medicine. 117: 436-438. PMID 1503336 DOI: 10.7326/0003-4819-117-5-436  0.112
1992 Herold KC, Rubenstein AH. New directions in the immunology of autoimmune diabetes Annals of Internal Medicine. 117: 436-438. PMID 1503336  0.112
1978 Karlin JB, Juhn DJ, Goldberg R, Rubenstein AH. Recent progress in the development of radioimmunoassays for human serum lipoproteins Annals of Clinical and Laboratory Science. 8: 142-154. PMID 205163  0.11
1970 Metzger AL, Rubenstein AH. Reversible cerebral oedema complicating diabetic ketoacidosis. British Medical Journal. 3: 746-7. PMID 4990632 DOI: 10.1136/bmj.3.5725.746  0.108
1992 Lernmark A, Morris PJ, Rubenstein AH. Diabetes and frontiers of research. Introduction. Diabetologia. 35: A9-11. PMID 1478374 DOI: 10.1007/Bf00586272  0.108
1992 Lernmark A, Morris PJ, Rubenstein AH. Diabetes and frontiers of research. Introduction. Diabetologia. 35: A9-11. PMID 1478374  0.108
1968 Rubenstein AH, Cho S, Steiner DF. Evidence for proinsulin in human urine and serum. Lancet (London, England). 1: 1353-5. PMID 4172655 DOI: 10.1016/S0140-6736(68)92040-0  0.098
1984 Kruse V, Heding LG, Jørgensen KH, Tronier B, Christensen M, Thim L, Frank BH, Root MA, Cohen RM, Rubenstein AH. Human proinsulin standards Diabetologia. 27: 414-415. PMID 6500201 DOI: 10.1007/BF00304860  0.098
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Causes, complications, and new screening recommendations. Part one of a three-part roundtable discussion Geriatrics. 53: 47-54. PMID 9511774  0.098
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Causes, complications, and new screening recommendations. Part one of a three-part roundtable discussion Geriatrics. 53: 47-54. PMID 9511774  0.098
1984 Jones LA, Teramoto T, Juhn DJ, Goldberg RB, Rubenstein AH, Getz GS. Characterization of lipoprotein produced by the perfused rhesus monkey liver Journal of Lipid Research. 25: 319-335. PMID 6427376  0.098
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Treatment goals and pharmaceutical therapies: Part two of a three-part roundtable discussion Geriatrics. 53: 42-51. PMID 9559027  0.095
1998 Butler RN, Rubenstein AH, Gracia AMG, Zweig SC. Type 2 diabetes: Treatment goals and pharmaceutical therapies: Part two of a three-part roundtable discussion Geriatrics. 53: 42-51. PMID 9559027  0.095
1971 Spitz IM, Bersohn I, Rubenstein AH, Van As M. The response of growth hormone to xylitol administration in man. The American Journal of the Medical Sciences. 60: 224-9. PMID 5496207 DOI: 10.1097/00000441-197010000-00004  0.095
1979 Gonen B, Rubenstein AH. Hemoglobin A1 and assessment of diabetic control Comprehensive Therapy. 5: 17-20. PMID 445985  0.094
1978 Gonen B, Rubenstein AH. Haemoglobin A1 and diabetes mellitus Diabetologia. 15: 1-8. PMID 355029 DOI: 10.1007/BF01219319  0.093
1978 Karlin JB, Juhn DJ, Scanu AM, Rubenstein AH. Measurement of serum apolipoprotein B by radioimmunoassay European Journal of Clinical Investigation. 8: 19-26. PMID 206447  0.09
1996 Rubenstein AH. A 64-year-old man with adult-onset diabetes Journal of the American Medical Association. 276: 816. PMID 8769592 DOI: 10.1001/jama.276.10.816  0.09
1996 Rubenstein AH. A 64-year-old man with adult-onset diabetes Journal of the American Medical Association. 276: 816. PMID 8769592 DOI: 10.1001/jama.276.10.816  0.09
1990 Tillil H, Frank BH, Pekar AH, Broelsch C, Rubenstein AH, Polonsky KS. Hypoglycemic potency and metabolic clearance rate of intravenously administered human proinsulin and metabolites Endocrinology. 127: 2418-2422. PMID 2226325  0.087
1980 Goldberg RB, Karlin JB, Juhn DJ, Scanu AM, Edelstein C, Rubenstein AH. Characterization and measurement of human apolipoprotein A-II by radioimmunoassay Journal of Lipid Research. 21: 902-912. PMID 6777442  0.087
1977 Rosenbloom AL, Rubenstein AH, Donnelly WJ. INFANTILE HYPOGLYCEMIA (HG) FROM FAMILIAL HYPERPROIN SULINISM (HPI) Pediatric Research. 11: 521-521. DOI: 10.1203/00006450-197704000-00909  0.077
1984 Kruse V, Heding LG, Jørgensen KH, Tronier B, Christensen M, Thim L, Frank BH, Root MA, Cohen RM, Rubenstein AH. Human proinsulin standards Diabetologia. 27: 414-415. PMID 6500201 DOI: 10.1007/BF00304860  0.073
2020 Pierson SK, Khor JS, Ziglar J, Liu A, Floess K, NaPier E, Gorzewski AM, Tamakloe MA, Powers V, Akhter F, Haljasmaa E, Jayanthan R, Rubenstein A, Repasky M, Elenitoba-Johnson K, et al. ACCELERATE: A Patient-Powered Natural History Study Design Enabling Clinical and Therapeutic Discoveries in a Rare Disorder. Cell Reports. Medicine. 1: 100158. PMID 33377129 DOI: 10.1016/j.xcrm.2020.100158  0.071
1984 Fless GM, Juhn D, Karlin J, Rubenstein A, Scanu AM. Response of rhesus serum high density lipoproteins to cycles of diet-induced hypercholesterolemia Arteriosclerosis. 4: 154-164. PMID 6422917  0.07
1970 Spitz IM, Rubenstein AH, Bersohn I, Bässler KH. Metabolism of xylitol in healthy subjects and patients with renal disease. Metabolism: Clinical and Experimental. 19: 24-34. PMID 5410660 DOI: 10.1016/0026-0495(70)90114-9  0.067
1982 Cooper RS, Goldberg RB, Trevisan M, Tsong Y, Liu K, Stamler J, Rubenstein A, Scanu AM. The selective lipid-lowering effect of vegetarianism on low density lipoproteins in a cross-over experiment Atherosclerosis. 44: 293-305. PMID 7150394 DOI: 10.1016/0021-9150(82)90004-1  0.066
1967 Kotler MN, Berman L, Rubenstein AH. Hypoglycaemia precipitated by propranolol. Lancet (London, England). 2: 1389-90. PMID 4163546 DOI: 10.1016/S0140-6736(66)90423-5  0.06
1984 Cooper R, Allen A, Goldberg R, Trevisan M, Van Horn L, Liu K, Steinhauer M, Rubenstein A, Stamler J. Seventh-day Adventist adolescents - Life-style patterns and cardiovascular risk factors Western Journal of Medicine. 140: 471-477. PMID 6710991  0.059
1983 Jackson R, Hamling J, Sim B, Blix P, Rubenstein A, Nabarro J. The Interpretation of Lactate Concentrations in Forearm Blood Clinical Science. 64: 35P-35P. DOI: 10.1042/CS064035P  0.057
1993 Oohashi H, Ohgawara H, Nanjo K, Tasaka Y, Cao QP, Shu Jin Chan, Rubenstein AH, Steiner DF, Omori Y. Familial hyperproinsulinemia associated with NIDDM: A case study Diabetes Care. 16: 1340-1346. PMID 8269791  0.054
1973 Borensztajn J, Keig P, Rubenstein AH. The role of glucagon in the regulation of myocardial lipoprotein lipase activity. Biochemical and Biophysical Research Communications. 53: 603-8. PMID 4716990 DOI: 10.1016/0006-291X(73)90704-3  0.053
1986 Block MB, Rubenstein AH. Aspirin-induced hypoglycaemia in a patient on haemodialysis. Lancet (London, England). 2: 1315. PMID 4143554 DOI: 10.1016/S0140-6736(71)90625-8  0.047
2021 Godley BF, Lawley TJ, Rubenstein A, Pizzo PA. How Academic Medical Centers Can Navigate the Pandemic and its Aftermath: Solutions for Three Major Issues. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 33983136 DOI: 10.1097/ACM.0000000000004155  0.046
2007 Bowman MA, Rubenstein AH, Levine AS. Clinical revenue investment in biomedical research: lessons from two academic medical centers. Jama. 297: 2521-4. PMID 17565088 DOI: 10.1001/Jama.297.22.2521  0.043
2007 Bowman MA, Rubenstein AH, Levine AS. Clinical revenue investment in biomedical research: lessons from two academic medical centers. Jama. 297: 2521-4. PMID 17565088 DOI: 10.1001/Jama.297.22.2521  0.043
1984 Jones LA, Teramoto T, Juhn DJ, Goldberg RB, Rubenstein AH, Getz GS. Characterization of lipoprotein produced by the perfused rhesus monkey liver Journal of Lipid Research. 25: 319-335. PMID 6427376  0.043
1970 Spitz I, Rubenstein AH, Bersohn I, Lawrence AM, Kirsteins L. The effect of dialysis on the carbohydrate intolerance of chronic renal failure Hormone and Metabolic Research. 2: 86-93. PMID 4939148 DOI: 10.1055/S-0028-1095114  0.043
1981 Ettlie JE, Rubenstein AH. Stimulating the flow of innovations to the U.S. automotive industry Technological Forecasting and Social Change. 19: 33-55. DOI: 10.1016/0040-1625(81)90048-2  0.043
1978 Kirsch KC, Rubenstein AH. Converting from hard copy to microfilm: An administrative experiment Collection Management. 2: 279-302. DOI: 10.1080/J105v02n04_02  0.041
1994 Albala A, Rubenstein AH. Significant issues for the future of product innovation The Journal of Product Innovation Management. 11: 156-161.  0.036
1994 Albala A, Rubenstein AH. Significant issues for the future of product innovation The Journal of Product Innovation Management. 11: 156-161.  0.036
1971 Konsek JP, Rubenstein AH, Ehrlich EN. Biologic action of proinsulin on ventral toad skin in vitro. Endocrinology. 89: 847-51. PMID 5566396 DOI: 10.1210/ENDO-89-3-847  0.034
1967 Seftel H, Goldin A, Rubenstein A. HYPEROSMOLAR NON-KETOTIC COMA The Lancet. 290: 1042-1043. DOI: 10.1016/S0140-6736(67)90318-2  0.034
2002 Rubenstein A. Summary remarks: the implications of professionalism for medical education. The Mount Sinai Journal of Medicine, New York. 69: 415-7. PMID 12429962  0.032
1999 Alberts BM, Ayala FJ, Botstein D, Frank E, Holmes EW, Lee RD, Macagno ER, Marrack P, Oparil S, Orkin SH, Rubenstein AH, Slayman CW, Sparling PF, Squire LR, von Hippel PH, et al. Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health. Science (New York, N.Y.). 285: 666-7. PMID 10454921 DOI: 10.1126/Science.285.5428.666  0.032
1999 Alberts BM, Ayala FJ, Botstein D, Frank E, Holmes EW, Lee RD, Macagno ER, Marrack P, Oparil S, Orkin SH, Rubenstein AH, Slayman CW, Sparling PF, Squire LR, von Hippel PH, et al. Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health. Science (New York, N.Y.). 285: 666-7. PMID 10454921 DOI: 10.1126/Science.285.5428.666  0.032
1982 Valenta LJ, Eisenberg H, Miller DR, Tanner SM, Romansky SG, Rubenstein AH, Mako M, Cullen BF, Golden MP, Elias AN. The value of artificial beta cell in the management of insulinoma. The Western Journal of Medicine. 137: 67-75. PMID 6291256  0.03
1979 Schedewie H, Elders J, Herzberg V, Bier D, Olefsky J, Rubenstein A. Carbohydrate Homeostasis in Children With Leprechaunism. Pediatric Research. 13: 1190-1190. DOI: 10.1203/00006450-197910000-00061  0.03
1979 Kaplan EL, Rubenstein AH, Evans R. Calcium infusion - a new provocative test for insulinomas British Journal of Surgery. 66: No. 9.  0.029
1978 Kaplan EL, Evans R, Rubenstein AH. Calcium infusion--a new provocative test for insulinomas The Proceedings of the Institute of Medicine of Chicago. 32: 68-69. PMID 219429  0.029
1969 Seftel HC, Rubenstein AH. Metabolic Response in Ethnic Groups Bmj. 2: 694-694. DOI: 10.1136/BMJ.2.5658.694-B  0.028
1992 Rubenstein AH. Research opportunities in the study of technical entrepreneurship in the large firm: A propositional inventory Journal of High Technology Management Research. 3: 83-110. DOI: 10.1016/1047-8310(92)90006-N  0.027
1992 Rubenstein AH. Research opportunities in the study of technical entrepreneurship in the large firm: A propositional inventory Journal of High Technology Management Research. 3: 83-110. DOI: 10.1016/1047-8310(92)90006-N  0.027
1996 RUBENSTEIN AH, ABRAHAMS C, STABLES DP, LEVIN NW. ACETOPHENETIDIN NEPHRITIS AND PAPILLARY NECROSIS: A CLINICAL AND PATHOLOGICAL STUDY OF SIX CASES. Archives of Internal Medicine. 113: 378-94. PMID 14096390 DOI: 10.1001/ARCHINTE.1964.00280090064011  0.027
2022 Davis PB, Meagher EA, Pomeroy C, Lowe WL, Rubenstein AH, Wu JY, Curtis AB, Jackson RD. Pandemic-related barriers to the success of women in research: a framework for action. Nature Medicine. PMID 35177858 DOI: 10.1038/s41591-022-01692-8  0.027
2001 Rubenstein AH, Geisler E, Hoffman G. IA business needs-based planning methodology for information systems in the firm International Journal of Manufacturing Technology and Management. 3: 75-87.  0.026
1985 Glaser MA, Rubenstein AH. Barriers to innovation - the R and D/production interface; some early findings Progress in Organic Coatings. 13: 237-252. DOI: 10.1016/0033-0655(85)80028-5  0.025
1985 Glaser MA, Rubenstein AH. Barriers to innovation - the R and D/production interface; some early findings Progress in Organic Coatings. 13: 237-252. DOI: 10.1016/0033-0655(85)80028-5  0.025
2005 Rubenstein AH. Obesity: a modern epidemic. Transactions of the American Clinical and Climatological Association. 116: 103-111; discussion . PMID 16555609  0.025
2005 Rubenstein AH. Obesity: a modern epidemic. Transactions of the American Clinical and Climatological Association. 116: 103-111; discussion . PMID 16555609  0.025
1980 Lee J, Rubenstein AH. An analysis of factors influencing the utilization of contract research in a developing country, Korea Research Policy. 9: 174-196. DOI: 10.1016/0048-7333(80)90011-6  0.024
1992 Rubenstein AH, Favus MJ. Research in progress at member institutions of the Central Society for Clinical Research: University of Chicago, Chicago, Illinois Journal of Laboratory and Clinical Medicine. 120: 666-670.  0.023
1992 Rubenstein AH, Favus MJ. Research in progress at member institutions of the Central Society for Clinical Research: University of Chicago, Chicago, Illinois Journal of Laboratory and Clinical Medicine. 120: 666-670.  0.023
1992 Thomson GE, Glassock RJ, Kimball HR, Rubenstein AH, Blank LL, Ball JR, Griner PF, Gunnar RM, Hildreth E, Maddrey WC, Shapiro HB, Boyle JF, Maloney MC, Nelson AR, Ogrod ES, et al. General internal medicine and general internists: Recognizing a national need Annals of Internal Medicine. 117: 778-779. PMID 1416580 DOI: 10.7326/0003-4819-117-9-778  0.023
1997 Rubenstein AH, Geisler E, Abeysinghe R. Industrial Practices of Research Conversion and Technology Transfer Journal of Technology Transfer. 22: 49-56.  0.022
1997 Rubenstein AH, Geisler E, Abeysinghe R. Industrial Practices of Research Conversion and Technology Transfer Journal of Technology Transfer. 22: 49-56.  0.022
2009 Rubenstein AH. Models and metrics for the technology transfer process from federal labs to application and the market Picmet: Portland International Center For Management of Engineering and Technology, Proceedings. 2760-2770. DOI: 10.1109/PICMET.2009.5261799  0.022
1978 Hurter AP, Rubenstein AH. Market penetration by new innovations: The technological literature Technological Forecasting and Social Change. 11: 197-221. DOI: 10.1016/0040-1625(78)90062-8  0.021
2007 Rubenstein AH, Geisler E. Improved metrics of the impacts of knowledge management: Linking proximal outcomes to critical success factors Portland International Conference On Management of Engineering and Technology. 1032-1037. DOI: 10.1109/PICMET.2007.4349424  0.021
2007 Rubenstein AH, Geisler E. Improved metrics of the impacts of knowledge management: Linking proximal outcomes to critical success factors Portland International Conference On Management of Engineering and Technology. 1032-1037. DOI: 10.1109/PICMET.2007.4349424  0.021
1927 Rubenstein AH. XLVI. The Ear, Nose and Throat in its Relations to General Medicine Annals of Otology, Rhinology & Laryngology. 36: 489-494. DOI: 10.1177/000348942703600216  0.021
1927 RUBENSTEIN AH. PEMPHIGUS OF THE THROAT: A SUPPLEMENTARY REPORT Archives of Otolaryngology - Head and Neck Surgery. 5: 349-350. DOI: 10.1001/ARCHOTOL.1927.00600010371008  0.02
2007 Wasserstein AG, Brennan PJ, Rubenstein AH. Institutional leadership and faculty response: Fostering professionalism at the University of Pennsylvania School of Medicine Academic Medicine. 82: 1049-1056. PMID 17971690 DOI: 10.1097/ACM.0b013e31815763d2  0.02
1926 MACGRUER HA, RUBENSTEIN AH. ACUTE PEMPHIGUS OF THE THROAT, WITH POSITIVE VINCENT'S ANGINA Archives of Otolaryngology - Head and Neck Surgery. 3: 259-261. DOI: 10.1001/ARCHOTOL.1926.00580010281006  0.02
1987 Ettlie JE, Rubenstein AH. Firm size and product innovation The Journal of Product Innovation Management. 4: 89-108. DOI: 10.1016/0737-6782(87)90055-5  0.019
1987 Ettlie JE, Rubenstein AH. Firm size and product innovation The Journal of Product Innovation Management. 4: 89-108. DOI: 10.1016/0737-6782(87)90055-5  0.019
1962 RUBENSTEIN AH, LEVIN NW, ELLIOTT GA. Hypoglycaemia induced by manganese. Nature. 194: 188-9. PMID 14494873 DOI: 10.1038/194188a0  0.019
1962 RUBENSTEIN AH, LEVIN NW, ELLIOTT GA. Manganese-induced hypoglycaemia. Lancet (London, England). 2: 1348-51. PMID 13982963 DOI: 10.1016/S0140-6736(62)91022-X  0.019
1986 Ginn ME, Rubenstein AH. The R&D/production interface: A case study of new product commercialization The Journal of Product Innovation Management. 3: 158-170. DOI: 10.1016/0737-6782(86)90049-4  0.019
1986 Ginn ME, Rubenstein AH. The R&D/production interface: A case study of new product commercialization The Journal of Product Innovation Management. 3: 158-170. DOI: 10.1016/0737-6782(86)90049-4  0.019
1972 Block MB, Gambetta M, Resnekov L, Rubenstein AH. Spontaneous hypoglycaemia in congestive heart-failure. Lancet (London, England). 2: 736-8. PMID 4116147 DOI: 10.1016/S0140-6736(72)92025-9  0.019
2000 Rubenstein AH. Research opportunities and needs in the management of medical technology (MMT) International Journal of Healthcare Technology and Management. 2: 147-162.  0.018
2011 Rubenstein AH, Maglothin M, Geisler E. A corporate or Central Research Lab (CRL) for hospital systems Picmet: Portland International Center For Management of Engineering and Technology, Proceedings.  0.018
1989 Sen F, Rubenstein AH. External technology and in-house R&D's facilitative role The Journal of Product Innovation Management. 6: 123-138. DOI: 10.1016/0737-6782(89)90006-4  0.017
1989 Sen F, Rubenstein AH. External technology and in-house R&D's facilitative role The Journal of Product Innovation Management. 6: 123-138. DOI: 10.1016/0737-6782(89)90006-4  0.017
1996 STABLES DP, LEVIN NW, RUBENSTEIN AH, BERK ME, ABRAHAMS C. PARATHYROIDECTOMY FOR HYPERCALCEMIC CRISIS IN RENAL OSTEODYSTROPHY. Annals of Internal Medicine. 61: 531-9. PMID 14218935 DOI: 10.7326/0003-4819-61-3-531  0.017
1986 Zhou LY, Rubenstein AH. Imbedded Technology Capability (ITC) and the management of science and technology in China: A research note Research Policy. 15: 49-51. DOI: 10.1016/0048-7333(86)90022-3  0.017
1986 Zhou LY, Rubenstein AH. Imbedded Technology Capability (ITC) and the management of science and technology in China: A research note Research Policy. 15: 49-51. DOI: 10.1016/0048-7333(86)90022-3  0.017
1996 Rubenstein AH. The future of the Association of American Physicians. Proceedings of the Association of American Physicians. 108: 390-397. PMID 8902883  0.017
1996 Rubenstein AH. The future of the Association of American Physicians. Proceedings of the Association of American Physicians. 108: 390-397. PMID 8902883  0.017
2003 Rubenstein AH. Payoffs from Government-Sponsored R&D in the U.S. and Japan Portland International Conference On Management of Engineering and Technology. 133-139.  0.017
2003 Rubenstein AH. Payoffs from Government-Sponsored R&D in the U.S. and Japan Portland International Conference On Management of Engineering and Technology. 133-139.  0.017
1970 Rubenstein AH, Rubenstein AH. Program of research on the management of research and development R&D Management. 1: 48-48. DOI: 10.1111/J.1467-9310.1970.TB01198.X  0.016
1992 Thomson GE, Glassock RJ, Kimball HR, Rubenstein AH, Blank LL, Ball JR, Griner PF, Gunnar RM, Hildreth E, Maddrey WC, Shapiro HB, Boyle JF, Maloney MC, Nelson AR, Ogrod ES, et al. General internal medicine and general internists: Recognizing a national need Annals of Internal Medicine. 117: 778-779. PMID 1416580  0.015
1988 Rubenstein AH, Geisler E, Grabowski B. MANAGING TECHNOLOGY IN FIRMS IN THE SERVICE INDUSTRIES. . 507-514.  0.015
1988 Rubenstein AH, Geisler E, Grabowski B. MANAGING TECHNOLOGY IN FIRMS IN THE SERVICE INDUSTRIES. . 507-514.  0.015
2009 Hendricks J, Newton CD, Rubenstein A. 'One Medicine - One Health' at the School of Veterinary Medicine of the University of Pennsylvania - the first 125 years. Veterinaria Italiana. 45: 183-94. PMID 20391397  0.014
1990 Sen F, Rubenstein AH. An Exploration of Factors Affecting the Integration of In-House R&D with External Technology Acquisition Strategies of a Firm Ieee Transactions On Engineering Management. 37: 246-258. DOI: 10.1109/17.62320  0.013
1993 Glickman RM, Bennett JC, Nolan JP, Stobo JD, Rubenstein AH, Mufson MA, Terwilliger J. United we stand Annals of Internal Medicine. 118: 903-904. PMID 8480967 DOI: 10.7326/0003-4819-118-11-199306010-00014  0.012
1993 Glickman RM, Bennett JC, Nolan JP, Stobo JD, Rubenstein AH, Mufson MA, Terwilliger J. United we stand Annals of Internal Medicine. 118: 903-904. PMID 8480967  0.012
1927 RUBENSTEIN AH. INTRANASAL ETHMOIDECTOMY: COURSE AND SEQUELAE ON FRACTURING LAMINA AND INSERTING PACK Archives of Otolaryngology - Head and Neck Surgery. 5: 162-167. DOI: 10.1001/ARCHOTOL.1927.00600010174007  0.012
1992 Prasad L, Rubenstein AH. Conceptualizing Organizational Politics as a Multidimensional Phenomenon: Empirical Evidence from a Study of Technological Innovations Ieee Transactions On Engineering Management. 39: 4-12. DOI: 10.1109/17.119658  0.011
1999 Kappel TA, Rubenstein AH. Creativity in design: The contribution of information technology Ieee Transactions On Engineering Management. 46: 132-143. DOI: 10.1109/17.759140  0.01
1999 Kappel TA, Rubenstein AH. Creativity in design: The contribution of information technology Ieee Transactions On Engineering Management. 46: 132-143. DOI: 10.1109/17.759140  0.01
2015 Feldman AM, Runge MS, Garcia JGN, Rubenstein AH. American medical education at a crossroads Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aaa2039  0.01
2009 Rubenstein AH. The five decades-long development of an engineering manager and the field of engineering management Emj - Engineering Management Journal. 21: 36-37.  0.01
2005 Schwartz MD, Basco WT, Grey MR, Elmore JG, Rubenstein A. Rekindling student interest in generalist careers. Annals of Internal Medicine. 142: 715-24. PMID 15838091 DOI: 10.7326/0003-4819-142-8-200504190-00040  0.01
2004 Rubenstein AH. 50 years of Engineering and Technology Management Ieee Transactions On Engineering Management. 51: 407-408. DOI: 10.1109/TEM.2004.836366  0.01
2004 Rubenstein AH. 50 years of Engineering and Technology Management Ieee Transactions On Engineering Management. 51: 407-408. DOI: 10.1109/TEM.2004.836366  0.01
1996 ABRAHAMS C, WHEATLEY A, RUBENSTEIN AH, STABLES D. HEPATOCELLULAR LIPOFUSCIN AFTER EXCESSIVE INGESTION OF ANALGESICS. Lancet (London, England). 2: 621-2. PMID 14186152 DOI: 10.1016/S0140-6736(64)90513-6  0.01
1996 ABRAHAMS C, RUBENSTEIN AH, LEVIN NW. PHENACETIN-INDUCED PAPILLARY DAMAGE IN EXPERIMENTAL ANIMALS. Nature. 200: 695-6. PMID 14109969 DOI: 10.1038/200695A0  0.01
1994 King JC, Bierman EL, Erdman JW, Garza C, Adkisson PL, Allen LH, Bier DM, Clydesdale FM, DeLuca HF, Doyle MP, Dwyer JT, Grundy SM, Hambridge M, Kolonel LN, Miller S, ... ... Rubenstein AH, et al. How should the recommended dietary allowances be revised? A concept paper from the Food and Nutrition Board Nutrition Reviews. 52: 216-219. PMID 7898787  0.01
1994 King JC, Bierman EL, Erdman JW, Garza C, Adkisson PL, Allen LH, Bier DM, Clydesdale FM, DeLuca HF, Doyle MP, Dwyer JT, Grundy SM, Hambridge M, Kolonel LN, Miller S, ... ... Rubenstein AH, et al. How should the recommended dietary allowances be revised? A concept paper from the Food and Nutrition Board Nutrition Reviews. 52: 216-219. PMID 7898787  0.01
1994 Rubenstein AH. Trends in Technology Management Revisited Ieee Transactions On Engineering Management. 41: 335-341. DOI: 10.1109/17.364555  0.01
1993 Grinbergs A, Rubenstein AH. Software-Engineering Management: A Comparison of Methods in Switzerland and the United States Ieee Transactions On Engineering Management. 40: 22-29. DOI: 10.1109/17.206646  0.01
1992 Rubenstein AH. Reflections on residency training: 1991 Journal of General Internal Medicine. 7: 217-220. PMID 1487770 DOI: 10.1007/BF02598018  0.01
1992 Rubenstein AH. Reflections on residency training: 1991 Journal of General Internal Medicine. 7: 217-220. PMID 1487770 DOI: 10.1007/BF02598018  0.01
1992 Lernmark A, Morris PJ, Rubenstein AH. Preface Diabetologia. 35: A9-A11. DOI: 10.1007/BF00586272  0.01
1992 Lernmark A, Morris PJ, Rubenstein AH. Preface Diabetologia. 35: A9-A11. DOI: 10.1007/BF00586272  0.01
1989 Rubenstein AH. The best of a very good group The Journal of Laboratory and Clinical Medicine. 113: A3.  0.01
1989 Rubenstein AH. The best of a very good group The Journal of Laboratory and Clinical Medicine. 113: A3.  0.01
1981 Rajan JV, Seth ND, Subramanian SK, Chakrabarti AK, Rubenstein AH. Transfer of indigenous technology-some indian cases Research Policy. 10: 172-194. DOI: 10.1016/0048-7333(81)90004-4  0.01
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