Stephen Hill - Related publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Boritzki V, Hübner H, Allikalt A, Gmeiner P, Wöhrl BM. Optimizing the Expression of Human Dopamine Receptors in . International Journal of Molecular Sciences. 22. PMID 34445358 DOI: 10.3390/ijms22168647   
2021 Nobrega JN, Raymond R, Rajji TK, Pollock BG. A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods. Journal of Pharmacological and Toxicological Methods. 107118. PMID 34481920 DOI: 10.1016/j.vascn.2021.107118   
2021 Gonias SL. Plasminogen activator receptor assemblies in cell-signaling, innate immunity, and inflammation. American Journal of Physiology. Cell Physiology. PMID 34406905 DOI: 10.1152/ajpcell.00269.2021   
2021 Eguchi A, Ueki A, Hoshiyama J, Kuwata K, Chikaoka Y, Kawamura T, Nagatoishi S, Tsumoto K, Ueki R, Sando S. A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells. Jacs Au. 1: 578-585. PMID 34467321 DOI: 10.1021/jacsau.0c00121   
2021 Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, et al. Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell Research. PMID 34561620 DOI: 10.1038/s41422-021-00569-8   
2021 van Aalst E, Wylie BJ. Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling. Frontiers in Molecular Biosciences. 8: 724603. PMID 34490352 DOI: 10.3389/fmolb.2021.724603   
2021 Mitra A, Sarkar A, Borics A. Universal Properties and Specificities of the β-Adrenergic Receptor-G Protein Complex Activation Mechanism Revealed by All-Atom Molecular Dynamics Simulations. International Journal of Molecular Sciences. 22. PMID 34638767 DOI: 10.3390/ijms221910423   
2021 Haider S, Pandey P, Reddy CR, Lambert JA, Chittiboyina AG. Novel Machaeriol Analogues as Modulators of Cannabinoid Receptors: Structure-Activity Relationships of (+)-Hexahydrocannabinoids and Their Isoform Selectivities. Acs Omega. 6: 20408-20421. PMID 34395989 DOI: 10.1021/acsomega.1c02413   
2021 Kong X, Li ZX, Gao YQ, Liu FH, Chen ZZ, Tian HG, Liu TX, Xu YY, Kang ZW. Genome-Wide Identification of Neuropeptides and Their Receptors in an Aphid Endoparasitoid Wasp, . Insects. 12. PMID 34442310 DOI: 10.3390/insects12080745   
2021 Lou L, Li C, Wang J, Wu A, Zhang T, Ma Z, Chai L, Zhang D, Zhao Y, Nie B, Jin Q, Chen H, Liu WJ. Yiqi Huoxue preserves heart function by upregulating the Sigma-1 receptor in rats with myocardial infarction. Experimental and Therapeutic Medicine. 22: 1308. PMID 34630662 DOI: 10.3892/etm.2021.10743   
2021 Smith C, Li A, Krishnamurthy N, Lemmon MA. Phosphatidylserine binding directly regulates TIM-3 function. The Biochemical Journal. PMID 34435619 DOI: 10.1042/BCJ20210425   
2021 Kumar S, Kumar N, Sharma CS, Mishra SS. Molecular Insights of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole as CRF-1 Receptor Antagonists: Combined QSAR, Glide Docking, Molecular Dynamics, and ADME Studies. Iranian Journal of Pharmaceutical Research : Ijpr. 20: 22-34. PMID 34567143 DOI: 10.22037/ijpr.2020.113746.14464   
2021 Binder P, Schnellbächer ND, Höfer T, Becker NB, Schwarz US. Optimal ligand discrimination by asymmetric dimerization and turnover of interferon receptors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34507994 DOI: 10.1073/pnas.2103939118   
2021 Turu G, Soltész-Katona E, Tóth AD, Juhász C, Cserző M, Misák Á, Balla A, Caron MG, Hunyady L. Biased Coupling to β-Arrestin of Two Common Variants of the CB Cannabinoid Receptor. Frontiers in Endocrinology. 12: 714561. PMID 34484125 DOI: 10.3389/fendo.2021.714561   
2021 Castillo G, Kleene R, Schachner M, Loers G, Torda AE. Proteins Binding to the Carbohydrate HNK-1: Common Origins? International Journal of Molecular Sciences. 22. PMID 34360882 DOI: 10.3390/ijms22158116   
2021 Yang W, Nan H, Xu Z, Huang Z, Chen S, Li J, Li J, Yang H. DNA-Templated Glycan Labeling for Monitoring Receptor Spatial Distribution in Living Cells. Analytical Chemistry. PMID 34474560 DOI: 10.1021/acs.analchem.1c01815   
2021 Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a   
2021 Kilpatrick LE, Hill SJ. The use of fluorescence correlation spectroscopy to characterise the molecular mobility of G protein-coupled receptors in membrane microdomains: an update. Biochemical Society Transactions. 49: 1547-1554. PMID 34436556 DOI: 10.1042/BST20201001   
2021 Levick SP. Histamine receptors in heart failure. Heart Failure Reviews. PMID 34622365 DOI: 10.1007/s10741-021-10166-x   
2021 Lee Y, Hou X, Lee JH, Nayak A, Alexander V, Sharma PK, Chang H, Phan K, Gao ZG, Jacobson KA, Choi S, Jeong LS. Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary. Journal of Medicinal Chemistry. PMID 34435786 DOI: 10.1021/acs.jmedchem.1c00239   
2021 Khan SA, Zia K, Ashraf S, Khan A, Ul-Haq Z. Theoretical investigation of selective ligand binding mode of galanin receptors. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 34632940 DOI: 10.1080/07391102.2021.1977703   
2021 Vaidya AS, Peterson FC, Eckhardt J, Xing Z, Park SY, Dejonghe W, Takeuchi J, Pri-Tal O, Faria J, Elzinga D, Volkman BF, Todoroki Y, Mosquna A, Okamoto M, Cutler SR. Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34531324 DOI: 10.1073/pnas.2108281118   
2021 Ren X, Gelinas AD, Linehan M, Iwasaki A, Wang W, Janjic N, Marie Pyle A. Title: Evolving a RIG-I antagonist: a modified DNA aptamer mimics viral RNA. Journal of Molecular Biology. 167227. PMID 34487794 DOI: 10.1016/j.jmb.2021.167227   
2021 Budzinski J, Maschauer S, Kobayashi H, Couvineau P, Vogt H, Gmeiner P, Roggenhofer A, Prante O, Bouvier M, Weikert D. Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer. Communications Biology. 4: 1062. PMID 34508168 DOI: 10.1038/s42003-021-02574-4   
2021 Mazeh AC, Angus JA, Wright CE. Pharmacological characterisation of the CB receptor antagonist activity of cannabidiol in the rat vas deferens bioassay. European Journal of Pharmacology. 174433. PMID 34416240 DOI: 10.1016/j.ejphar.2021.174433   
2021 Cong X, Maurel D, Déméné H, Vasiliauskaité-Brooks I, Hagelberger J, Peysson F, Saint-Paul J, Golebiowski J, Granier S, Sounier R. Molecular insights into the biased signaling mechanism of the μ-opioid receptor. Molecular Cell. PMID 34433090 DOI: 10.1016/j.molcel.2021.07.033   
2021 Lenglez S, Sablon A, Fénelon G, Boland A, Deleuze JF, Boutoleau-Bretonnière C, Nicolas G, Demoulin JB. Distinct functional classes of PDGFRB pathogenic variants in primary familial brain calcification. Human Molecular Genetics. PMID 34494111 DOI: 10.1093/hmg/ddab258   
2021 Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y. Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. European Journal of Pharmacology. 174491. PMID 34506779 DOI: 10.1016/j.ejphar.2021.174491   
2021 Powell WS. Eicosanoid receptors as therapeutic targets for asthma. Clinical Science (London, England : 1979). 135: 1945-1980. PMID 34401905 DOI: 10.1042/CS20190657   
2021 Manoliu LCE, Martin EC, Milac AL, Spiridon L. Effective Use of Empirical Data for Virtual Screening against APJR GPCR Receptor. Molecules (Basel, Switzerland). 26. PMID 34443478 DOI: 10.3390/molecules26164894   
2021 Deganutti G, Atanasio S, Rujan RM, Sexton PM, Wootten D, Reynolds CA. Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors. Frontiers in Molecular Biosciences. 8: 720561. PMID 34513925 DOI: 10.3389/fmolb.2021.720561   
2021 Sharma A, Kumar GA, Chattopadhyay A. Late Endosomal/Lysosomal Accumulation of a Neurotransmitter Receptor in a Cellular Model of Smith-Lemli-Opitz Syndrome. Traffic (Copenhagen, Denmark). PMID 34418249 DOI: 10.1111/tra.12811   
2021 Leo LM, Abood ME. CB1 Cannabinoid Receptor Signaling and Biased Signaling. Molecules (Basel, Switzerland). 26. PMID 34500853 DOI: 10.3390/molecules26175413   
2021 Harvey RD, Clancy CE. Mechanisms of cAMP compartmentation in cardiac myocytes: Experimental and computational approaches to understanding. The Journal of Physiology. PMID 34510451 DOI: 10.1113/JP280801   
2021 Jin C, Yi C, Zhong W, Xue Y, Chen K, Deng K, Wang Z, Wang T. Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT receptor agonists for migraine therapy. European Journal of Medicinal Chemistry. 225: 113782. PMID 34419891 DOI: 10.1016/j.ejmech.2021.113782   
2021 Mahadik N, Bhattacharya D, Padmanabhan A, Sakhare K, Narayan KP, Banerjee R. Targeting steroid hormone receptors for anti-cancer therapy-A review on small molecules and nanotherapeutic approaches. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1755. PMID 34541822 DOI: 10.1002/wnan.1755   
2021 Yuan Y, Jia G, Wu C, Wang W, Cheng L, Li Q, Li Z, Luo K, Yang S, Yan W, Su Z, Shao Z. Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition. Cell Research. PMID 34526663 DOI: 10.1038/s41422-021-00566-x   
2021 Peterson JL, Ceresa BP. Epidermal Growth Factor Receptor Expression in the Corneal Epithelium. Cells. 10. PMID 34572058 DOI: 10.3390/cells10092409   
2021 Wang X, Sandberg ML, Martin AD, Negri KR, Gabrelow GB, Nampe DP, Wu ML, McElvain ME, Toledo Warshaviak D, Lee WH, Oh J, Daris ME, Chai F, Yao C, Furney J, et al. Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 34432728 DOI: 10.1097/CJI.0000000000000386   
2021 Tutzauer J, Gonzalez de Valdivia E, Swärd K, Alexandrakis Eilard I, Broselid S, Kahn R, Olde B, Leeb-Lundberg LMF. Molecular Pharmacology. PMID 34330822 DOI: 10.1124/molpharm.121.000259   
2021 Zhang J, Tang W, Bhatia NK, Xu Y, Paudyal N, Liu D, Kim S, Song R, XiangWei W, Shaulsky G, Myers SJ, Dobyns W, Jayaraman V, Traynelis SF, Yuan H, et al. A Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. Frontiers in Genetics. 12: 694312. PMID 34413877 DOI: 10.3389/fgene.2021.694312   
2021 Meng Q, Fu Y, Li S, Yan Y, Duan D, Anthony DD, Zhu Y, Wu X, Qian F, Wu C. Rapid, sensitive and cost-effective determination of immune checkpoint inhibitor activity using a magnetic bead-based binding assay. Journal of Immunological Methods. 113134. PMID 34464606 DOI: 10.1016/j.jim.2021.113134   
2021 Kumar R, Grinberg AV, Li H, Kuo TH, Sako D, Krishnan L, Liharska K, Li J, Grenha R, Maguire MC, Briscoe SD, Pearsall RS, Herrin BR, Suragani RNVS, Castonguay R. Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily. Scientific Reports. 11: 18341. PMID 34526551 DOI: 10.1038/s41598-021-97203-9   
2021 Reinmuth L, Hsiao CC, Hamann J, Rosenkilde M, Mackrill J. Multiple Targets for Oxysterols in Their Regulation of the Immune System. Cells. 10. PMID 34440846 DOI: 10.3390/cells10082078   
2021 Sánchez-Melgar A, Muñoz-López S, Albasanz JL, Martín M. Antitumoral Action of Resveratrol Through Adenosinergic Signaling in C6 Glioma Cells. Frontiers in Neuroscience. 15: 702817. PMID 34539333 DOI: 10.3389/fnins.2021.702817   
2021 Ishida A, Okabe Y, Matsushita T, Sekiguchi T, Nishio T, Komagata T, Iwaki M, Miyata H, Katagi J, Naganawa A, Maruyama T, Imagawa A. Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis. Bioorganic & Medicinal Chemistry. 49: 116424. PMID 34626901 DOI: 10.1016/j.bmc.2021.116424   
2021 Yang MY, Kim SK, Kim D, Liggett SB, Goddard WA. Structures and Agonist Binding Sites of Bitter Taste Receptor TAS2R5 Complexed with Gi Protein and Validated against Experiment. The Journal of Physical Chemistry Letters. 9293-9300. PMID 34542294 DOI: 10.1021/acs.jpclett.1c02162   
2021 Cevheroğlu O, Murat M, Mingu-Akmete S, Son ÇD. Ste2p Under the Microscope: the Investigation of Oligomeric States of a Yeast G Protein-Coupled Receptor. The Journal of Physical Chemistry. B. 125: 9526-9536. PMID 34433281 DOI: 10.1021/acs.jpcb.1c05872   
2021 Sisignano M, Fischer MJM, Geisslinger G. Proton-Sensing GPCRs in Health and Disease. Cells. 10. PMID 34440817 DOI: 10.3390/cells10082050   
2021 Gonzalez CU, Carrillo E, Berka V, Jayaraman V. Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors. Membranes. 11. PMID 34436376 DOI: 10.3390/membranes11080613