J L Flippen-Anderson - Publications

Affiliations: 
Lab for Structure of Matter US Naval Research Lab 

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Henrick K, Feng Z, Bluhm WF, Dimitropoulos D, Doreleijers JF, Dutta S, Flippen-Anderson JL, Ionides J, Kamada C, Krissinel E, Lawson CL, Markley JL, Nakamura H, Newman R, Shimizu Y, et al. Remediation of the protein data bank archive. Nucleic Acids Research. 36: D426-33. PMID 18073189 DOI: 10.1093/nar/gkm937  0.52
2005 Deng H, Gifford AN, Zvonok AM, Cui G, Li X, Fan P, Deschamps JR, Flippen-Anderson JL, Gatley SJ, Makriyannis A. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. Journal of Medicinal Chemistry. 48: 6386-92. PMID 16190764 DOI: 10.1021/jm050135l  0.92
2005 Crisma M, Deschamps JR, George C, Flippen-Anderson JL, Kaptein B, Broxterman QB, Moretto A, Oancea S, Jost M, Formaggio F, Toniolo C. A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 564-79. PMID 15885116 DOI: 10.1111/j.1399-3011.2005.00258.x  0.92
2005 Wang YN, Bohle DS, Bonifant CL, Chmurny GN, Collins JR, Davies KM, Deschamps J, Flippen-Anderson JL, Keefer LK, Klose JR, Saavedra JE, Waterhouse DJ, Ivanic J. Chemistry of the diazeniumdiolates: Z ⇌ E isomerism Journal of the American Chemical Society. 127: 5388-5395. PMID 15826177 DOI: 10.1021/ja042258l  0.52
2005 Deshpande N, Addess KJ, Bluhm WF, Merino-Ott JC, Townsend-Merino W, Zhang Q, Knezevich C, Xie L, Chen L, Feng Z, Green RK, Flippen-Anderson JL, Westbrook J, Berman HM, Bourne PE. The RCSB Protein Databa Bank: A redesigned query system and relational database based on the mmCIF schema Nucleic Acids Research. 33: D233-D237. PMID 15608185 DOI: 10.1093/nar/gki057  0.52
2004 Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/jo040159k  0.92
2004 Yu H, Kim IJ, Folk JE, Tian X, Rothman RB, Baumann MH, Dersch CM, Flippen-Anderson JL, Parrish D, Jacobson AE, Rice KC. Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters. Journal of Medicinal Chemistry. 47: 2624-34. PMID 15115403 DOI: 10.1021/jm0305873  0.4
2004 Kodato S, Linders JT, Gu XH, Yamada K, Flippen-Anderson JL, Deschamps JR, Jacobson AE, Rice KC. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers. Organic & Biomolecular Chemistry. 2: 330-6. PMID 14747861 DOI: 10.1039/b312633c  0.92
2003 Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α -(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide and (-)-4-[(αR)-α -(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide Bioorganic and Medicinal Chemistry. 11: 4761-4768. PMID 14556791 DOI: 10.1016/S0968-0896(03)00496-6  0.52
2003 Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, Farkas T, Johnson KM, Wang S. 2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry. 11: 1123-36. PMID 12614900 DOI: 10.1016/S0968-0896(02)00450-9  0.52
2003 Przybyl AK, Flippen-Anderson JL, Jacobson AE, Rice KC. Practical and high-yield syntheses of dihydromorphine from tetrahydrothebaine and efficient syntheses of (8S)-8-bromomorphide. The Journal of Organic Chemistry. 68: 2010-3. PMID 12608825 DOI: 10.1021/jo0206871  0.4
2003 Chen W, Wu H, Bernard D, Metcalf MD, Deschamps JR, Flippen-Anderson JL, MacKerell AD, Coop A. Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine. The Journal of Organic Chemistry. 68: 1929-32. PMID 12608812 DOI: 10.1021/jo020704m  0.52
2002 Deschamps JR, Flippen-Anderson JL, George C. X-ray studies on ligands. Biopolymers. 66: 287-93. PMID 12539257 DOI: 10.1002/bip.10308  0.92
2002 Bryant SD, George C, Flippen-Anderson JL, Deschamps JR, Salvadori S, Balboni G, Guerrini R, Lazarus LH. Crystal structures of dipeptides containing the Dmt-Tic pharmacophore Journal of Medicinal Chemistry. 45: 5506-5513. PMID 12459018 DOI: 10.1021/jm020330p  0.52
2002 Hashimoto A, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan. Bioorganic & Medicinal Chemistry. 10: 3319-29. PMID 12150879  0.92
2002 Prakash KR, Tang Y, Kozikowski AP, Flippen-Anderson JL, Knoblach SM, Faden AI. Synthesis and biological activity of novel neuroprotective diketopiperazines. Bioorganic & Medicinal Chemistry. 10: 3043-8. PMID 12110327 DOI: 10.1016/S0968-0896(02)00132-3  0.52
2002 Deschamps JR, George C, Flippen-Anderson JL. (1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o362-4. PMID 12050443  0.92
2002 Flippen-Anderson JL, Deschamps JR, George C, Hruby VJ, Misicka A, Lipkowski AW. Crystal structure of biphalin sulfate: a multireceptor opioid peptide. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 123-33. PMID 11985706  0.92
2001 Zhang Y, Joseph DB, Bowen WD, Flippen-Anderson JL, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues. Journal of Medicinal Chemistry. 44: 3937-45. PMID 11689080 DOI: 10.1021/jm0101592  0.52
2001 Zhang J, Flippen-Anderson JL, Kozikowski AP. A tandem Michael addition ring-closure route to the metabotropic receptor ligand α-(hydroxymethyl)glutamic acid and its γ-alkylated derivatives Journal of Organic Chemistry. 66: 7555-7559. PMID 11681981 DOI: 10.1021/jo010626n  0.52
2001 Keefer LK, Flippen-Anderson JL, George C, Shanklin AP, Dunams TM, Christodoulou D, Saavedra JE, Sagan ES, Bohle DS. Chemistry of the diazeniumdiolates. I. Structural and spectral characteristics of the [N(O)NO]- functional group. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 377-94. PMID 11485376 DOI: 10.1006/niox.2001.0359  0.52
2001 Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP. Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors. Journal of Medicinal Chemistry. 44: 1615-22. PMID 11334571 DOI: 10.1021/jm000552s  0.52
2001 Thomas JB, Herault XM, Rothman RB, Atkinson RN, Burgess JP, Mascarella SW, Dersch CM, Xu H, Flippen-Anderson JL, George CF, Carroll FI. Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides. Journal of Medicinal Chemistry. 44: 972-87. PMID 11300879 DOI: 10.1021/jm000427g  0.52
2000 Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. Journal of Medicinal Chemistry. 43: 4868-76. PMID 11123996  0.92
2000 Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, Tella S, Kozikowski AP. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors. Journal of Medicinal Chemistry. 43: 1215-22. PMID 10737754 DOI: 10.1021/jm9905561  0.52
1999 Monaco V, Formaggio F, Crisma M, Toniolo C, Hanson P, Millhauser G, George C, Deschamps JR, Flippen-Anderson JL. Determining the occurrence of a 310-helix and an α-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C(α)-tetrasubstituted α-aminoacid Bioorganic and Medicinal Chemistry. 7: 119-131. PMID 10199662 DOI: 10.1016/S0968-0896(98)00220-X  0.52
1998 Thomas JB, Mascarella SW, Burgess JP, Xu H, McCullough KB, Rothman RB, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 3149-52. PMID 9873693  0.52
1998 Thomas JB, Zheng X, Mascarella SW, Rothman RB, Dersch CM, Partilla JS, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. Journal of Medicinal Chemistry. 41: 4143-9. PMID 9767649 DOI: 10.1021/jm980290i  0.52
1998 Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, George C, Saiah E. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton. Journal of Medicinal Chemistry. 41: 1962-9. PMID 9599245 DOI: 10.1021/jm980028+  0.52
1997 Deschamps JR, Flippen-Anderson JL, Moore C, Cudney R, George C. Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-hydrate and tyrosyl-D-tetrahydroisoquinoline-3-carboxamide hydrate. Acta Crystallographica. Section C, Crystal Structure Communications. 53: 1478-82. PMID 9362554  0.92
1997 Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. Journal of Medicinal Chemistry. 40: 2936-47. PMID 9288176 DOI: 10.1021/jm970106d  0.52
1997 Flippen-Anderson JL, Deschamps JR, George C, Reddy PA, Lewin AH, Brine GA, Sheldrick G, Nikiforovich G. X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 384-93. PMID 9211219  0.92
1997 Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands. Journal of Medicinal Chemistry. 40: 695-704. PMID 9057856 DOI: 10.1021/jm960319n  0.4
1996 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Effects of end group and aggregation on helix conformation: crystal structure of Ac-(Aib-Val-Ala-Leu)2-Aib-OMe. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 106-16. PMID 9225250 DOI: 10.1002/psc.52  0.52
1996 George C, Flippen-Anderson JL, Bianco A, Crisma M, Formaggio F, Toniolo C. Crystallographic characterization of tryptophan-containing peptide 3(10)-helices. Peptide Research. 9: 315-21. PMID 9048426  0.92
1996 Deschamps JR, George C, Flippen-Anderson JL. A diacetylmorphine polymorph. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 698-700. PMID 9004734  0.92
1996 Crisma M, Bianco A, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Tryptophan-containing polypeptide 3(10)-helices. Side-chain interactions and molecular recognition studies. Advances in Experimental Medicine and Biology. 398: 623-6. PMID 8906336  0.92
1996 Deschamps JR, George C, Flippen-Anderson JL. [D-Ala2,D-Leu5]-enkephalin hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 1583-5. PMID 8766899  0.92
1996 Flippen-Anderson JL, George C, Valle G, Valente E, Bianco A, Formaggio F, Crisma M, Toniolo C. Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides. International Journal of Peptide and Protein Research. 47: 231-8. PMID 8738647  0.92
1996 Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity. Journal of Medicinal Chemistry. 39: 2081-6. PMID 8642567 DOI: 10.1021/jm950695s  0.4
1996 Yamada K, Rice KC, Flippen-Anderson JL, Eissenstat MA, Ward SJ, Johnson MR, Howlett AC. (Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor. Journal of Medicinal Chemistry. 39: 1967-74. PMID 8642555 DOI: 10.1021/jm950932r  0.52
1996 Deschamps JR, George C, Flippen-Anderson JL. Structural studies of opioid peptides: a review of recent progress in x-ray diffraction studies. Biopolymers. 40: 121-39. PMID 8541444 DOI: 10.1002/bip.360400102  0.92
1995 Bertha CM, Flippen-Anderson JL, Rothman RB, Porreca F, Davis P, Xu H, Becketts K, Cha XY, Rice KC. Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands. Journal of Medicinal Chemistry. 38: 1523-37. PMID 7739011  0.4
1995 Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype. Journal of Medicinal Chemistry. 38: 4776-85. PMID 7490727  0.52
1994 Flippen-Anderson JL, George C, Deschamps JR. Methyl N,N-diallyl-O-tert-butyltyrosyl-alpha-aminoisobutyrl-alpha- aminoisobutyrate, C28H43N3O5. Acta Crystallographica. Section C, Crystal Structure Communications. 50: 1095-7. PMID 8074811  0.92
1994 Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist. Journal of Medicinal Chemistry. 37: 2125-8. PMID 8035418  0.4
1994 Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Conformation of the flexible bent helix of Leu1-zervamicin in crystal C and a possible gating action for ion passage. Biopolymers. 34: 721-35. PMID 8025219 DOI: 10.1002/bip.360340605  0.52
1994 Flippen-Anderson JL, Deschamps JR, Clifford George, Ward KB, Houghten R. Crystal structure of deltakephalin: A δ-selective opioid peptide with a novel β-bend-like conformation International Journal of Peptide and Protein Research. 44: 97-104. PMID 7982763  0.52
1994 Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands. Journal of Medicinal Chemistry. 37: 3163-70. PMID 7932540  0.4
1994 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Hydration and distortion of peptide helices in crystals. Alpha-helical structure of a dodecapeptide, Boc-(Ala-Leu-Aib)4-OMe. International Journal of Peptide and Protein Research. 44: 491-8. PMID 7896509  0.52
1994 Karle IL, Flippen-Anderson JL, Gurunath R, Balaram P. Facile transition between 3(10)- and alpha-helix: structures of 8-, 9-, and 10-residue peptides containing the -(Leu-Aib-Ala)2-Phe-Aib- fragment. Protein Science : a Publication of the Protein Society. 3: 1547-55. PMID 7833814 DOI: 10.1002/pro.5560030920  0.52
1993 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Unfolding of an alpha-helix in peptide crystals by solvation: conformational fragility in a heptapeptide. Biopolymers. 33: 827-37. PMID 8343578 DOI: 10.1002/bip.360330511  0.52
1993 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Peptide mimics for structural features in proteins. Crystal structures of three heptapeptide helices with a C-terminal 6-->1 hydrogen bond. International Journal of Peptide and Protein Research. 42: 401-10. PMID 8106192  0.52
1992 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Helix packing of leucine-rich peptides: a parallel leucine ladder in the structure of Boc-Aib-Leu-Aib-Aib-Leu-Leu-Leu-Aib-Leu-Aib-OMe. Proteins. 12: 324-30. PMID 1579566 DOI: 10.1002/prot.340120404  0.52
1992 Flippen-Anderson JL, George C. Absolute configuration of (-)-alpha-acetylmethadol hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 48: 1855-7. PMID 1445673  0.92
1992 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Differences in hydration and association of helical Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe.xH2O in two crystalline polymorphs. Journal of Medicinal Chemistry. 35: 3885-9. PMID 1433198  0.52
1992 Agarwalla S, Mellor IR, Sansom MS, Karle IL, Flippen-Anderson JL, Uma K, Krishna K, Sukumar M, Balaram P. Zervamicins, a structurally characterised peptide model for membrane ion channels. Biochemical and Biophysical Research Communications. 186: 8-15. PMID 1378732 DOI: 10.1016/S0006-291X(05)80768-5  0.52
1991 Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Archiv Der Pharmazie. 324: 29-33. PMID 2043039  0.92
1991 Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 88: 5307-11. PMID 1711227  0.52
1990 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Parallel and antiparallel aggregation of alpha-helices. Crystal structures of two apolar decapeptides X-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe (X = Boc, Ac). International Journal of Peptide and Protein Research. 35: 518-26. PMID 2401593  0.52
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Peptide design: influence of a guest Aib-Pro segment on the stereochemistry of an oligo-val sequence--solution conformations and crystal structure of Boc-(Val)2-Aib-Pro-(Val)3-OMe. Biopolymers. 29: 1433-42. PMID 2361154 DOI: 10.1002/bip.360291010  0.52
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: crystal structure of hepta- and octapeptides containing alpha-aminoisobutyric acid. Proteins. 7: 62-73. PMID 2330369 DOI: 10.1002/prot.340070107  0.52
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Synthetic peptide helices in crystals: structure and antiparallel and skewed packing motifs for alpha-helices in two isomeric decapeptides. Biopolymers. 30: 719-31. PMID 2275974 DOI: 10.1002/bip.360300707  0.52
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Parallel zippers formed by alpha-helical peptide columns in crystals of Boc-Aib-Glu(OBzl)-Leu-Aib-Ala-Leu-Aib-Ala-Lys(Z)-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 87: 7921-5. PMID 2236010  0.52
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Helix aggregation in peptide crystals: occurrence of either all parallel or antiparallel packing motifs for alpha-helices in polymorphs of Boc-Aib-Ala-Leu-Ala-Leu-Aib-Leu-Ala-Leu-Aib-OMe. Biopolymers. 29: 1835-45. PMID 2207288 DOI: 10.1002/bip.360291414  0.52
1990 Lin AJ, Li LQ, Klayman DL, George CF, Flippen-Anderson JL. Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 3. Aromatic amine analogues. Journal of Medicinal Chemistry. 33: 2610-4. PMID 2202831 DOI: 10.1021/jm00171a041  0.52
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 86: 765-9. PMID 2915976  0.52
1989 Karle IL, Flippen-Anderson JL, Kishore R, Balaram P. Cystine peptides. Antiparallel beta-sheet conformation of the cyclic biscystine peptide [Boc-Cys-Ala-Cys-NHCH3]2. International Journal of Peptide and Protein Research. 34: 37-41. PMID 2793307  0.52
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Modular design of synthetic protein mimics. Characterization of the helical conformation of a 13-residue peptide in crystals. Biochemistry. 28: 6696-701. PMID 2790024  0.52
1989 Karle IL, Flippen-Anderson JL, Wieland T. Conformational stability of antamanide and analogs. Crystal structure of perhydrosymmetric antamanide, cyclic (-Val-Pro-Pro-Cha-Cha-Val-Pro-Pro-Cha-Cha-). International Journal of Peptide and Protein Research. 33: 422-7. PMID 2777476  0.52
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Solvated helical backbones: x-ray diffraction study of Boc-Ala-Leu-Aib-Ala-Leu-Aib-OMe.H2O. Biopolymers. 28: 773-81. PMID 2706314 DOI: 10.1002/bip.360280307  0.52
1989 Flippen-Anderson JL, George C, Gilardi R, Yu QS, Dominguez L, Brossi A. Structure of an ether dimer of deoxydihydroqinghaosu, a potential metabolite of the antimalarial arteether. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 292-4. PMID 2610970  0.92
1989 Karle IL, Flippen-Anderson JL. Three conformers in a crystal of N-Ac-L-Leu-L-Tyr-OMe. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 791-5. PMID 2604941 DOI: 10.1107/S0108270188014118  0.52
1988 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Aggregation studies in crystals of apolar helical peptides: Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe. International Journal of Peptide and Protein Research. 32: 536-43. PMID 3246478  0.52
1988 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Monoclinic polymorph of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe(anhydrous). Parallel packing of 3(10)-/alpha-helices and a transition of helix type. International Journal of Peptide and Protein Research. 31: 567-76. PMID 3079530  0.52
1986 Pavanand K, Nutakul W, Dechatiwongse T, Yoshihira K, Yongvanitchit K, Scovill JP, Flippen-Anderson JL, Gilardi R, George C, Kanchanapee P. In vitro antimalarial activity of Brucea javanica against multi-drug resistant Plasmodium falciparum. Planta Medica. 108-11. PMID 3523552  0.92
1986 Schönenberger B, Jacobson AE, Brossi A, Streaty R, Klee WA, Flippen-Anderson JL, Gilardi R. Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogues in antinociceptive assays: confirmation of rubreserine structure by X-ray analysis. Journal of Medicinal Chemistry. 29: 2268-73. PMID 3023611  0.48
1985 Jarvis BB, Lee YW, Yatawara CS, Mazzocchi DB, Flippen-Anderson JL, Gilardi R, George C. 7 alpha-hydroxytrichodermol, a new trichothecene from Myrothecium roridum. Applied and Environmental Microbiology. 50: 1225-8. PMID 4091555  0.92
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