J L Flippen-Anderson - Publications

Affiliations: 
Lab for Structure of Matter U.S. Naval Research Laboratory, Washington, DC, United States 

37/249 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Crisma M, Deschamps JR, George C, Flippen-Anderson JL, Kaptein B, Broxterman QB, Moretto A, Oancea S, Jost M, Formaggio F, Toniolo C. A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 564-79. PMID 15885116 DOI: 10.1111/J.1399-3011.2005.00258.X  0.321
2002 Bryant SD, George C, Flippen-Anderson JL, Deschamps JR, Salvadori S, Balboni G, Guerrini R, Lazarus LH. Crystal structures of dipeptides containing the Dmt-Tic pharmacophore Journal of Medicinal Chemistry. 45: 5506-5513. PMID 12459018 DOI: 10.1021/Jm020330P  0.416
2002 Flippen-Anderson JL, Deschamps JR, George C, Hruby VJ, Misicka A, Lipkowski AW. Crystal structure of biphalin sulfate: a multireceptor opioid peptide. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 123-33. PMID 11985706 DOI: 10.1034/J.1399-3011.2002.01967.X  0.33
2001 Deschamps JR, Flippen-Anderson JL, Brine GA, Hayes JP, George C. Boc-tyrosyl-D-alanyl-glycyl-N-methyl-phenylalanyl-O-methyl-methionine hydrate: a protected analog of metkephamid Acta Crystallographica Section E Structure Reports Online. 58: o13-o15. DOI: 10.1107/S1600536801020475  0.328
1998 Deschamps JR, George C, Flippen-Anderson JL. The relationship between structure and activity among opioid peptides Letters in Peptide Science. 5: 337-340. DOI: 10.1007/Bf02443482  0.335
1997 Deschamps JR, Flippen-Anderson JL, Moore C, Cudney R, George C. Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-hydrate and tyrosyl-D-tetrahydroisoquinoline-3-carboxamide hydrate. Acta Crystallographica. Section C, Crystal Structure Communications. 53: 1478-82. PMID 9362554 DOI: 10.1107/S0108270197006975  0.306
1997 Gilardi R, Flippen-Anderson J, George C, Butcher RJ. A New Class of Flexible Energetic Salts:  The Crystal Structures of the Ammonium, Lithium, Potassium, and Cesium Salts of Dinitramide Journal of the American Chemical Society. 119: 9411-9416. DOI: 10.1021/Ja9709280  0.335
1996 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Effects of end group and aggregation on helix conformation: crystal structure of Ac-(Aib-Val-Ala-Leu)2-Aib-OMe. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 106-16. PMID 9225250 DOI: 10.1002/Psc.52  0.363
1996 George C, Flippen-Anderson JL, Bianco A, Crisma M, Formaggio F, Toniolo C. Crystallographic characterization of tryptophan-containing peptide 3(10)-helices. Peptide Research. 9: 315-21. PMID 9048426  0.33
1996 Collins N, Flippen-Anderson JL, Haaseth RC, Deschamps JR, George C, Kövér K, Hruby VJ. Conformational Determinants of Agonist versus Antagonist Properties of [d-Pen2,d-Pen5]Enkephalin (DPDPE) Analogs at Opioid Receptors. Comparison of X-ray Crystallographic Structure, Solution1H NMR Data, and Molecular Dynamic Simulations of [l-Ala3]DPDPE and [d-Ala3]DPDPE Journal of the American Chemical Society. 118: 2143-2152. DOI: 10.1021/Ja9531081  0.343
1996 Butcher RJ, Gilardi RD, George C, Flippen-Anderson J. Distortions in nitramine substituted cubanes: The structures of N,N′-dinitro-1,4-diaminocubane, N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane, and 1,2,4,7-tetrakis(N-methoxycarbonylnitramino)cubane Journal of Chemical Crystallography. 26: 381-388. DOI: 10.1007/Bf01665815  0.322
1994 Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Conformation of the flexible bent helix of Leu1-zervamicin in crystal C and a possible gating action for ion passage. Biopolymers. 34: 721-35. PMID 8025219 DOI: 10.1002/Bip.360340605  0.339
1994 Flippen-Anderson JL, Deschamps JR, Clifford George, Ward KB, Houghten R. Crystal structure of deltakephalin: A δ-selective opioid peptide with a novel β-bend-like conformation International Journal of Peptide and Protein Research. 44: 97-104. PMID 7982763 DOI: 10.1111/J.1399-3011.1994.Tb00563.X  0.426
1994 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Hydration and distortion of peptide helices in crystals. Alpha-helical structure of a dodecapeptide, Boc-(Ala-Leu-Aib)4-OMe. International Journal of Peptide and Protein Research. 44: 491-8. PMID 7896509 DOI: 10.1111/J.1399-3011.1994.Tb00187.X  0.332
1994 Lomize AL, Flippen-Anderson JL, George C, Mosberg HI. Conformational analysis of the δ receptor-selective, cyclic opioid peptide, Tyr-cyclo[D-Cys-Phe-D-Pen]OH (JOM-13). Comparison of X-ray crystallographic structures, molecular mechanics simulations, and 1H NMR data Journal of the American Chemical Society. 116. DOI: 10.1021/Ja00081A001  0.308
1994 Flippen-Anderson JL, George C, Deschamps JR, Reddy PA, Lewin AH, Brine GA. X-ray structures of the ? opioid antagonist TIPP and a protected derivative of the ? opioid antagonist ICI 174,864 Letters in Peptide Science. 1: 107-115. DOI: 10.1007/Bf00128528  0.443
1993 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Accommodation of a D-Phe residue into a right-handed 3(10)-helix: structure of Boc-D-Phe-(Aib)4-Gly-L-Leu-(Aib)2-OMe, an analogue of the amino terminal segment of antiamoebins and emerimicins. Biopolymers. 33: 401-7. PMID 8461451 DOI: 10.1002/Bip.360330308  0.319
1993 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Unfolding of an alpha-helix in peptide crystals by solvation: conformational fragility in a heptapeptide. Biopolymers. 33: 827-37. PMID 8343578 DOI: 10.1002/Bip.360330511  0.394
1993 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Peptide mimics for structural features in proteins. Crystal structures of three heptapeptide helices with a C-terminal 6-->1 hydrogen bond. International Journal of Peptide and Protein Research. 42: 401-10. PMID 8106192  0.354
1992 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Helix packing of leucine-rich peptides: a parallel leucine ladder in the structure of Boc-Aib-Leu-Aib-Aib-Leu-Leu-Leu-Aib-Leu-Aib-OMe. Proteins. 12: 324-30. PMID 1579566 DOI: 10.1002/Prot.340120404  0.355
1992 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Differences in hydration and association of helical Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe.xH2O in two crystalline polymorphs. Journal of Medicinal Chemistry. 35: 3885-9. PMID 1433198 DOI: 10.1021/Jm00099A016  0.34
1991 Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 88: 5307-11. PMID 1711227 DOI: 10.1073/Pnas.88.12.5307  0.354
1990 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Parallel and antiparallel aggregation of alpha-helices. Crystal structures of two apolar decapeptides X-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe (X = Boc, Ac). International Journal of Peptide and Protein Research. 35: 518-26. PMID 2401593  0.334
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Peptide design: influence of a guest Aib-Pro segment on the stereochemistry of an oligo-val sequence--solution conformations and crystal structure of Boc-(Val)2-Aib-Pro-(Val)3-OMe. Biopolymers. 29: 1433-42. PMID 2361154 DOI: 10.1002/Bip.360291010  0.367
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: crystal structure of hepta- and octapeptides containing alpha-aminoisobutyric acid. Proteins. 7: 62-73. PMID 2330369 DOI: 10.1002/Prot.340070107  0.379
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Synthetic peptide helices in crystals: structure and antiparallel and skewed packing motifs for alpha-helices in two isomeric decapeptides. Biopolymers. 30: 719-31. PMID 2275974 DOI: 10.1002/Bip.360300707  0.355
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Parallel zippers formed by alpha-helical peptide columns in crystals of Boc-Aib-Glu(OBzl)-Leu-Aib-Ala-Leu-Aib-Ala-Lys(Z)-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 87: 7921-5. PMID 2236010 DOI: 10.1073/Pnas.87.20.7921  0.37
1990 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Helix aggregation in peptide crystals: occurrence of either all parallel or antiparallel packing motifs for alpha-helices in polymorphs of Boc-Aib-Ala-Leu-Ala-Leu-Aib-Leu-Ala-Leu-Aib-OMe. Biopolymers. 29: 1835-45. PMID 2207288 DOI: 10.1002/Bip.360291414  0.352
1989 Karle IL, Flippen-Anderson JL, Kishore R, Balaram P. Cystine peptides. Antiparallel beta-sheet conformation of the cyclic biscystine peptide [Boc-Cys-Ala-Cys-NHCH3]2. International Journal of Peptide and Protein Research. 34: 37-41. PMID 2793307 DOI: 10.1111/J.1399-3011.1989.Tb01005.X  0.302
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Modular design of synthetic protein mimics. Characterization of the helical conformation of a 13-residue peptide in crystals. Biochemistry. 28: 6696-701. PMID 2790024 DOI: 10.1021/Bi00442A024  0.345
1989 Karle IL, Flippen-Anderson JL, Wieland T. Conformational stability of antamanide and analogs. Crystal structure of perhydrosymmetric antamanide, cyclic (-Val-Pro-Pro-Cha-Cha-Val-Pro-Pro-Cha-Cha-). International Journal of Peptide and Protein Research. 33: 422-7. PMID 2777476  0.369
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Solvated helical backbones: x-ray diffraction study of Boc-Ala-Leu-Aib-Ala-Leu-Aib-OMe.H2O. Biopolymers. 28: 773-81. PMID 2706314 DOI: 10.1002/Bip.360280307  0.329
1989 Karle IL, Flippen-Anderson JL. Three conformers in a crystal of N-Ac-L-Leu-L-Tyr-OMe. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 791-5. PMID 2604941 DOI: 10.1107/S0108270188014118  0.304
1989 Marchand AP, Dave PR, Rajapaksa D, Arney BE, Flippen-Anderson JL, Gilardi R, George C. Synthesis of 4,4,8,8,11,11-hexanitropentacyclo[5.4.0.02,6.03,10.05,9]undecane The Journal of Organic Chemistry. 54: 1769-1771. DOI: 10.1021/Jo00268A056  0.314
1988 Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Aggregation studies in crystals of apolar helical peptides: Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe. International Journal of Peptide and Protein Research. 32: 536-43. PMID 3246478 DOI: 10.1111/J.1399-3011.1988.Tb01385.X  0.33
1988 Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Monoclinic polymorph of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe(anhydrous). Parallel packing of 3(10)-/alpha-helices and a transition of helix type. International Journal of Peptide and Protein Research. 31: 567-76. PMID 3079530  0.325
1988 Karle IL, Flippen-Anderson J, Uma K, Balaram P. Aqueous channels within apolar peptide aggregates: solvated helix of the alpha-aminoisobutyric acid (Aib)-containing peptide Boc-(Aib-Ala-Leu)3-Aib-OMe.2H2O.CH3OH in crystals. Proceedings of the National Academy of Sciences of the United States of America. 85: 299-303. PMID 2448772 DOI: 10.1073/Pnas.85.2.299  0.35
Low-probability matches (unlikely to be authored by this person)
1997 Crisma M, Monaco V, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Crystallographic structure of a helical lipopeptaibol antibiotic analogue Letters in Peptide Science. 4: 213-218. DOI: 10.1007/Bf02442878  0.298
1990 Karle IL, Flippen-Anderson JL, Uma K, Sukumar M, Balaram P. Modular design of synthetic protein mimics. Crystal structures, assembly, and hydration of two 15- and 16-residue apolar, Leucyl-rich helical peptides Journal of the American Chemical Society. 112: 9350-9356.  0.297
1996 Deschamps JR, George C, Flippen-Anderson JL. Structural studies of opioid peptides: a review of recent progress in x-ray diffraction studies. Biopolymers. 40: 121-39. PMID 8541444 DOI: 10.1002/Bip.360400102  0.297
1994 Karle IL, Flippen-Anderson JL, Gurunath R, Balaram P. Facile transition between 3(10)- and alpha-helix: structures of 8-, 9-, and 10-residue peptides containing the -(Leu-Aib-Ala)2-Phe-Aib- fragment. Protein Science : a Publication of the Protein Society. 3: 1547-55. PMID 7833814 DOI: 10.1002/Pro.5560030920  0.296
1991 Karle IL, Flippen-Anderson JL, Sukumar M, Uma K, Balaram P. Modular design of synthetic protein mimics. Crystal structure of two seven-residue helical peptide segments linked by ε-aminocaproic acid Journal of the American Chemical Society. 113: 3952-3956.  0.294
1984 FLIPPEN-ANDERSON JL, GILARDI R, KARLE IL, FREY MH, OPELLA SJ, GIERASCH LM, GOODMAN M, MADISON V, DELANEY NG. ChemInform Abstract: CRYSTAL STRUCTURES, MOLECULAR CONFORMATIONS, INFRARED SPECTRA, AND CARBON-13 NMR SPECTRA OF METHYLPROLINE PEPTIDES IN THE SOLID STATE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198405070  0.292
2000 Deschamps JR, Flippen-Anderson JL, George C. 2-[N-(tert-Butoxycarbonyl)tyrosyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid nitromethane solvate Acta Crystallographica Section E Structure Reports Online. 57: o87-o90. DOI: 10.1107/S1600536800020109  0.292
1987 Karle IL, Flippen-Anderson J, Sukumar M, Balaram P. Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon. Proceedings of the National Academy of Sciences of the United States of America. 84: 5087-91. PMID 3474641 DOI: 10.1073/Pnas.84.15.5087  0.291
1991 Deschamps JR, George C, Flippen-Anderson JL, Musallam HA. Imidazolium chloride organophosphate antidotes Journal of Chemical Crystallography. 27: 541-548. DOI: 10.1007/Bf02576445  0.287
1996 Flippen-Anderson JL, George C, Valle G, Valente E, Bianco A, Formaggio F, Crisma M, Toniolo C. Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides. International Journal of Peptide and Protein Research. 47: 231-8. PMID 8738647 DOI: 10.1111/J.1399-3011.1996.Tb01350.X  0.286
2002 Deschamps JR, Flippen-Anderson JL, George C. X-ray studies on ligands. Biopolymers. 66: 287-93. PMID 12539257 DOI: 10.1002/Bip.10308  0.285
1999 Doi M, Ishida T, Kobayashi M, Deschamps JR, Flippen-Anderson JL. The highly solvated structure of theonellapeptolide Id, a tridecapeptide lactone from the Okinawa marine spongeTheonella swinhoei Acta Crystallographica Section C Crystal Structure Communications. 55: 796-798. DOI: 10.1107/S0108270198014383  0.283
1999 Monaco V, Formaggio F, Crisma M, Toniolo C, Hanson P, Millhauser G, George C, Deschamps JR, Flippen-Anderson JL. Determining the occurrence of a 310-helix and an α-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C(α)-tetrasubstituted α-aminoacid Bioorganic and Medicinal Chemistry. 7: 119-131. PMID 10199662 DOI: 10.1016/S0968-0896(98)00220-X  0.283
1989 Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 86: 765-9. PMID 2915976 DOI: 10.1073/Pnas.86.3.765  0.281
1978 Karle IL, Flippen-Anderson JL. Conformation of the cyclic tetrapeptide cyclo(-L-leucyl-L-tyrosyl-δ-amino valeryl-δ-aminovaleryl-) crystallized from acetone/H2O and comparison with the crystal from acetone/DMSO Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34: 3237-3241. DOI: 10.1107/S0567740878010572  0.281
1997 Flippen-Anderson JL, Deschamps JR, George C, Reddy PA, Lewin AH, Brine GA, Sheldrick G, Nikiforovich G. X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 384-93. PMID 9211219 DOI: 10.1111/J.1399-3011.1997.Tb00890.X  0.279
1984 Flippen-Anderson JL, D'Antonio P, Konnert JH. Crystal structure of (E)-5-hydroxypyrrolizidin-3-one and (Z)-5-thioketalpyrrolizidin-3-one Journal of Crystallographic and Spectroscopic Research. 14: 565-572. DOI: 10.1007/BF01182143  0.276
2004 Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/Jo040159K  0.274
1996 Deschamps JR, George C, Flippen-Anderson JL. [D-Ala2,D-Leu5]-enkephalin hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 1583-5. PMID 8766899 DOI: 10.1107/S0108270196000534  0.273
1996 Deschamps JR, George C, Flippen-Anderson JL. A diacetylmorphine polymorph. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 698-700. PMID 9004734 DOI: 10.1107/S0108270195013503  0.272
1990 Marchand AP, Annapurna P, Taylor RW, Simmons DL, Watson WH, Nagl A, Flippen-Anderson JL, Gilardi R, George C. Unusual behavior of 34:10,11-bis(2',3'-quinolino)tricyclo-[6.3.0.02,6] undecane upon attempted monoprotonation with triflic acid Tetrahedron. 46: 5077-5084. DOI: 10.1016/S0040-4020(01)87814-5  0.262
2005 Cao H, Van Ornum SG, Deschamps J, Flippen-Anderson J, Laib F, Cook JM. Synthesis of dicyclopenta[a,e]pentalenes via a molybdenum carbonyl mediated tandem allenic Pauson-Khand reaction and the X-ray crystal structure of a planar dicyclopenta[a,e]pentalene. Journal of the American Chemical Society. 127: 933-43. PMID 15656632 DOI: 10.1021/Ja040120X  0.24
1989 Flippen-Anderson JL, George C, Gilardi R, Yu QS, Dominguez L, Brossi A. Structure of an ether dimer of deoxydihydroqinghaosu, a potential metabolite of the antimalarial arteether. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 292-4. PMID 2610970  0.236
1998 Thomas JB, Zheng X, Mascarella SW, Rothman RB, Dersch CM, Partilla JS, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. Journal of Medicinal Chemistry. 41: 4143-9. PMID 9767649 DOI: 10.1021/jm980290i  0.235
1999 Toniolo C, Formaggio F, Crisma M, Mazaleyrat J, Wakselman M, George C, Deschamps JR, Flippen-Anderson JL, Pispisa B, Venanzi M, Palleschi A. First Peptide-Based System of Rigid Donor-Rigid Interchromophore Spacer-Rigid Acceptor: A Structural and Photophysical Study Chemistry - a European Journal. 5: 2254-2264. DOI: 10.1002/(Sici)1521-3765(19990802)5:8<2254::Aid-Chem2254>3.0.Co;2-1  0.23
2003 Linders J, Mirsadeghi S, Flippen-Anderson J, George C, Jacobson A, Rice K. Probes for Narcotic Receptor Mediated Phenomena Helvetica Chimica Acta. 86: 484-493. DOI: 10.1002/Hlca.200390048  0.227
2001 Thomas JB, Herault XM, Rothman RB, Atkinson RN, Burgess JP, Mascarella SW, Dersch CM, Xu H, Flippen-Anderson JL, George CF, Carroll FI. Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides. Journal of Medicinal Chemistry. 44: 972-87. PMID 11300879 DOI: 10.1021/jm000427g  0.227
1990 FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, REDDY GM. ChemInform Abstract: Structure of Diethyl 3,6-Dihydroxy-11,11-dimethoxypentacyclo(6.5.0.04,12.05,10.09,13)tridecane-2,6-diene-2,7-dicarboxylate. Cheminform. 21. DOI: 10.1002/CHIN.199005054  0.226
1990 Jarvis BB, Mazzocchi DB, Ammon HL, Mazzola EP, Flippen-Anderson JL, Gilardi RD, George CF. Conformational effects in trichothecenes: structures of 15-hydroxy C4 and C8 ketones The Journal of Organic Chemistry. 55: 3660-3662. DOI: 10.1021/JO00298A053  0.224
1986 Schönenberger B, Jacobson AE, Brossi A, Streaty R, Klee WA, Flippen-Anderson JL, Gilardi R. Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogues in antinociceptive assays: confirmation of rubreserine structure by X-ray analysis. Journal of Medicinal Chemistry. 29: 2268-73. PMID 3023611  0.224
2003 Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α -(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide and (-)-4-[(αR)-α -(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide Bioorganic and Medicinal Chemistry. 11: 4761-4768. PMID 14556791 DOI: 10.1016/S0968-0896(03)00496-6  0.224
1989 Flippen-Anderson JL, Gilardi R, George C, Marchand AP, Reddy GM. Structure of diethyl 3,6-dihydroxy-11,11-dimethoxypentacyclo[6.5.0.04,12.05,10.09,13]tridecane-2,6-diene-2,7-dicarboxylate Acta Crystallographica Section C Crystal Structure Communications. 45: 1548-1551. DOI: 10.1107/S0108270189001757  0.221
1987 Flippen-Anderson JL, Gilardi R, George C. Structure of 6-hydroxy-2,5-dinitro-2,5-diazacyclohexyl acetate Acta Crystallographica Section C Crystal Structure Communications. 43: 2022-2023. DOI: 10.1107/S0108270187089170  0.217
1984 Karle IL, Flippen-Anderson JL, Chiang JF, Lowrey AH. The conformations of five tetra- and pentamethoxylated phenyl derivatives: weberine analogs and polymethoprims Acta Crystallographica Section B Structural Science. 40: 500-506. DOI: 10.1107/S010876818400255X  0.216
2001 Flippen-Anderson JL, Deschamps JR, George C, Folk JE, Jacobson AE, Rice KC. Twinned 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenyl)propyl)piperazinium chloride (GBR12909) Acta Crystallographica Section E Structure Reports Online. 58: o81-o82. DOI: 10.1107/S1600536801021389  0.215
1997 Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands. Journal of Medicinal Chemistry. 40: 695-704. PMID 9057856 DOI: 10.1021/Jm960319N  0.214
1989 FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, REDDY GM. ChemInform Abstract: Structure of a 3-Methylpentacyclo(5.4.0.02,6.03,10.05,9)undecane-8,11-dione Monoethylene Ketal. Cheminform. 20. DOI: 10.1002/CHIN.198939134  0.214
1991 Oliver JE, Waters RM, Lusby WR, Flippen-Anderson JL. A macrocyclic amide from dehydrochlorination of indole-3-carbonyl chloride Journal of Heterocyclic Chemistry. 28: 1569-1572. DOI: 10.1002/JHET.5570280619  0.212
1991 Gilardi R, George C, Flippen-Anderson JL, Zajac WW, Walters TR, Woods JM. Structure of 1-amino-3,5,7-trinitroadamantane Acta Crystallographica Section C: Crystal Structure Communications. 47: 1914-1916. DOI: 10.1107/S0108270191001853  0.211
2010 Doi M, Ishida T, Kobayashi M, Deschamps JR, Flippen-Anderson JL. ChemInform Abstract: The Highly Solvated Structure of Theonellapeptolide Id, a Tridecapeptide Lactone from the Okinawa Marine Sponge Theonella swinhoei. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199932213  0.21
1986 GLEASON FK, PORWOLL J, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: X-Ray Structure Determination of the Naturally Occurring Isomer of Cyanobacterin. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198650066  0.208
1999 Yu H, Wang L, Flippen-Anderson JL, Tian X, Coop A, Rice KC. Synthesis of a novel 7,14β-ethano-bridged opiate Heterocycles. 51: 2343-2347. DOI: 10.3987/Com-99-8591  0.208
1993 Flippen-Anderson JL, Zajac WW, Buzby JH, Walters TR. Structure of 1-benzoyl-4,4,5,5-tetramethyl-2-phenylimidazoline hydrate Acta Crystallographica Section C Crystal Structure Communications. 49: 1792-1793. DOI: 10.1107/S0108270193002276  0.207
1994 Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands. Journal of Medicinal Chemistry. 37: 3163-70. PMID 7932540 DOI: 10.1021/Jm00045A022  0.206
1996 Flippen-Anderson JL, Deschamps J, George C, Hruby VJ, Li G, Lipkowski AW, Misicka A. Biphalin, a highly potent dimeric enkephalin analog Acta Crystallographica Section a Foundations of Crystallography. 52: C253-C253. DOI: 10.1107/S0108767396089325  0.203
1991 Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Archiv Der Pharmazie. 324: 29-33. PMID 2043039 DOI: 10.1002/Ardp.19913240109  0.201
1986 Gleason FK, Porwoll J, Flippen-Anderson JL, George C. X-ray structure determination of the naturally occurring isomer of cyanobacterin The Journal of Organic Chemistry. 51: 1615-1616. DOI: 10.1021/Jo00359A050  0.2
2002 Deschamps JR, George C, Flippen-Anderson JL. (1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o362-4. PMID 12050443 DOI: 10.1107/S0108270102006443  0.197
2005 Runyon SP, Burgess JP, Abraham P, Keverline-Frantz KI, Flippen-Anderson J, Deschamps J, Lewin AH, Navarro HA, Boja JW, Kuhar MJ, Carroll FI. Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product. Bioorganic & Medicinal Chemistry. 13: 2439-49. PMID 15755646 DOI: 10.1016/J.Bmc.2005.01.046  0.197
2002 Hashimoto A, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan. Bioorganic & Medicinal Chemistry. 10: 3319-29. PMID 12150879 DOI: 10.1016/S0968-0896(02)00219-5  0.196
2000 Hoepping A, Johnson KM, George C, Flippen-Anderson J, Kozikowski AP. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter. Journal of Medicinal Chemistry. 43: 2064-71. PMID 10821718 DOI: 10.1021/Jm0001121  0.194
2010 OLIVER JE, WATERS RM, LUSBY WR, FLIPPEN-ANDERSON JL. ChemInform Abstract: A Macrocyclic Amide from Dehydrochlorination of Indole-3-carbonyl Chloride. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199213237  0.192
1989 FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, DAVE PR. ChemInform Abstract: Structure of a Cage Dimer and a Dimer Ketone Formed via Thermal Reaction of Ethyl 3-Phenyl-2-norbornadienecarboxylate with Pentacarbonyliron Cheminform. 20. DOI: 10.1002/CHIN.198947048  0.191
1991 Gilardi R, Flippen-Anderson JL, George C. Structure of 2,2-dinitro-1,3-propanediyl bis[(N-pentafluorosulfanyl)carbamate] (I) and 2-fluoro-2,2-dinitroethyl (N-pentafluorosulfanyl)carbamate (II) Acta Crystallographica Section C Crystal Structure Communications. 47: 442-445. DOI: 10.1107/S0108270190006977  0.191
1992 Flippen-Anderson JL, George C. Absolute configuration of (-)-alpha-acetylmethadol hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 48: 1855-7. PMID 1445673  0.19
1992 Gilardi R, George C, Flippen-Anderson JL. Structure of 1,1,3,3-tetranitrocyclobutane Acta Crystallographica Section C Crystal Structure Communications. 48: 1680-1681. DOI: 10.1107/S0108270192000702  0.19
2003 Przybyl AK, Flippen-Anderson JL, Jacobson AE, Rice KC. Practical and high-yield syntheses of dihydromorphine from tetrahydrothebaine and efficient syntheses of (8S)-8-bromomorphide. The Journal of Organic Chemistry. 68: 2010-3. PMID 12608825 DOI: 10.1021/Jo0206871  0.187
1996 Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity. Journal of Medicinal Chemistry. 39: 2081-6. PMID 8642567 DOI: 10.1021/Jm950695S  0.186
2004 Kodato S, Linders JT, Gu XH, Yamada K, Flippen-Anderson JL, Deschamps JR, Jacobson AE, Rice KC. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers. Organic & Biomolecular Chemistry. 2: 330-6. PMID 14747861 DOI: 10.1039/B312633C  0.186
2001 Yu Q, Holloway HW, Flippen-Anderson JL, Hoffman B, Brossi A, Greig NH. Methyl analogues of the experimental Alzheimer drug phenserine: synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action. Journal of Medicinal Chemistry. 44: 4062-71. PMID 11708910 DOI: 10.1021/Jm010080X  0.186
1992 Agarwalla S, Mellor IR, Sansom MS, Karle IL, Flippen-Anderson JL, Uma K, Krishna K, Sukumar M, Balaram P. Zervamicins, a structurally characterised peptide model for membrane ion channels. Biochemical and Biophysical Research Communications. 186: 8-15. PMID 1378732 DOI: 10.1016/S0006-291X(05)80768-5  0.185
1995 Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype. Journal of Medicinal Chemistry. 38: 4776-85. PMID 7490727 DOI: 10.1021/Jm00024A005  0.184
1983 BROSSI A, ATWELL L, JACOBSON AE, ROZWADOWSKA MD, SCHMIDHAMMER H, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: STRUCTURE-ACTIVITY RELATIONSHIP OF OXYGENATED MORPHINANS. VII. 5-METHYLATED AND 14-HYDROXY-SUBSTITUTED AGONISTS AND ANTAGONISTS OF THE 4-HYDROXY- AND 3,4-DIOXYGENATED 6-MORPHINANONE SERIES Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198315343  0.183
1998 Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, George C, Saiah E. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton. Journal of Medicinal Chemistry. 41: 1962-9. PMID 9599245 DOI: 10.1021/Jm980028+  0.18
1993 Flippen-Anderson JL, George C, Deschamps J. Hydrogen-bonding patterns in X-ray diffraction studies of neuropeptides Acta Crystallographica Section a Foundations of Crystallography. 49: c144-c144. DOI: 10.1107/S0108767378095872  0.18
2005 Wang YN, Bohle DS, Bonifant CL, Chmurny GN, Collins JR, Davies KM, Deschamps J, Flippen-Anderson JL, Keefer LK, Klose JR, Saavedra JE, Waterhouse DJ, Ivanic J. Chemistry of the diazeniumdiolates: Z ⇌ E isomerism Journal of the American Chemical Society. 127: 5388-5395. PMID 15826177 DOI: 10.1021/Ja042258L  0.179
1982 Brossi A, Atwell L, Jacobson AE, Rozwadowska MD, Schmidhammer H, Flippen-Anderson JL, Gilardi R. Structure-Activity Relationship of Oxygenated Morphinans. VII. 5-Methylated and 14-Hydroxy-substituted Agonists and Antagonists of the 4-Hydroxy- and 3, 4-Dioxygenated 6-Morphinanone Series Helvetica Chimica Acta. 65: 2394-2404. DOI: 10.1002/HLCA.19820650804  0.179
1981 Spencer GF, Flippen-Anderson JL. Isolation and X-ray structure determination of a neolignan from Clerodendron inerme seeds Phytochemistry. 20: 2757-2759. DOI: 10.1016/0031-9422(81)85281-8  0.177
1994 Flippen-Anderson JL, George C, Deschamps JR. Methyl N,N-diallyl-O-tert-butyltyrosyl-alpha-aminoisobutyrl-alpha- aminoisobutyrate, C28H43N3O5. Acta Crystallographica. Section C, Crystal Structure Communications. 50: 1095-7. PMID 8074811 DOI: 10.1107/S0108270193012387  0.176
2003 Chen W, Metcalf MD, Coop A, Flippen-Anderson JL, Deschamps JR. 5-Butylthevinone: Stereochemistry of the Diels-Alder reaction of 5-butylthebaine with 3-buten-2-one Acta Crystallographica Section E: Structure Reports Online. 59: o114-i116. DOI: 10.1107/S1600536802023413  0.176
1983 Fodor G, Arnold R, Mohacsi T, Karle I, Flippen-Anderson J. A new role for l-ascorbic acid: michael donor to α,β-unsaturated carbonyl compounds Tetrahedron. 39: 2137-2145. DOI: 10.1016/S0040-4020(01)91929-5  0.175
2003 Yu J, Wang T, Liu X, Deschamps J, Flippen-Anderson J, Liao X, Cook JM. General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine. The Journal of Organic Chemistry. 68: 7565-81. PMID 14510528 DOI: 10.1021/Jo030006H  0.175
1997 Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. Journal of Medicinal Chemistry. 40: 2936-47. PMID 9288176 DOI: 10.1021/Jm970106D  0.175
1987 Flippen-Anderson JL, Gilardi R, George C. Structure of bruceine B hydrate Acta Crystallographica Section C Crystal Structure Communications. 43: 801-803. DOI: 10.1107/S0108270187094022  0.174
1992 Flippen-Anderson JL, George C, Gilardi R. Structure of 2,4,6-trinitro-8,10-dipropionyl-2,4,6,8,10-pentaazabicyclo[5.3.0]decane Acta Crystallographica Section C Crystal Structure Communications. 48: 1530-1531. DOI: 10.1107/S0108270191015123  0.174
2001 Zhang Y, Joseph DB, Bowen WD, Flippen-Anderson JL, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues. Journal of Medicinal Chemistry. 44: 3937-45. PMID 11689080 DOI: 10.1021/Jm0101592  0.174
1992 Gilardi R, George C, Flippen-Anderson JL. Structure of 3-nitrato-1-nitroazetidine Acta Crystallographica Section C Crystal Structure Communications. 48: 1679-1680. DOI: 10.1107/S0108270192000696  0.173
2010 PEI X, GREIG NH, FLIPPEN-ANDERSON JL, BI S, BROSSI A. ChemInform Abstract: Total Synthesis of Racemic and Optically Active Compounds Related to Physostigmine and Ring-C Heteroanalogues from 3-(2′-(Dimethylamino) ethyl)-2,3-dihydro-5-methoxy-1,3-dimethyl-1H-indol-2-ol. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199452244  0.172
1994 Pei X, Greig NH, Flippen-Anderson JL, Bi S, Brossi A. Total Synthesis of Racemic and Optically Active Compounds Related to Physostigmine and Ring-C Heteroanalogues from 3-[2?-(dimethylamino)ethyl]2,3-dihydro-5-methoxy-1,3-dimethyl-1H-indo l-2-ol Helvetica Chimica Acta. 77: 1412-1422. DOI: 10.1002/HLCA.19940770519  0.169
2001 Keefer LK, Flippen-Anderson JL, George C, Shanklin AP, Dunams TM, Christodoulou D, Saavedra JE, Sagan ES, Bohle DS. Chemistry of the diazeniumdiolates. I. Structural and spectral characteristics of the [N(O)NO]- functional group. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 377-94. PMID 11485376 DOI: 10.1006/Niox.2001.0359  0.168
2001 Ma C, Liu X, Li X, Flippen-Anderson J, Yu S, Cook JM. Efficient asymmetric synthesis of biologically important tryptophan analogues via a palladium-mediated heteroannulation reaction. The Journal of Organic Chemistry. 66: 4525-42. PMID 11421771 DOI: 10.1021/Jo001679S  0.167
1995 Bertha CM, Flippen-Anderson JL, Rothman RB, Porreca F, Davis P, Xu H, Becketts K, Cha XY, Rice KC. Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands. Journal of Medicinal Chemistry. 38: 1523-37. PMID 7739011 DOI: 10.1021/Jm00009A013  0.165
1989 George C, Flippen-Anderson JL, Gilardi R. Structure of the simple trichothecene 7α-hydroxyscirpene Acta Crystallographica Section C Crystal Structure Communications. 45: 1663-1665. DOI: 10.1107/S0108270189006979  0.164
1995 Lei PS, Ogawa Y, Flippen-Anderson JL, Kovác P. Synthesis and crystal structure of methyl 4-6-dideoxy-4-(3-deoxy-L- glycero-tetronamido)-2-O-methyl-alpha-D-mannopyranoside, the methyl alpha-glycoside of the terminal unit, and presumed antigenic determinant, of the O-specific polysaccharide of Vibrio cholerae O:1, serotype Ogawa. Carbohydrate Research. 275: 117-29. PMID 7585718  0.163
1982 Jarvis BB, Midiwo JO, Flippen-Anderson JL, Mazzola EP. Stereochemistry of the Roridins Journal of Natural Products. 45: 440-448. DOI: 10.1021/NP50022A014  0.162
1989 Yu QS, Yeh HJ, Brossi A, Flippen-Anderson JL. Geneserine and geneseroline revisited: acid-base catalyzed equilibria of hexahydropyrrolo-[2,3-b]-indole N-oxides with hexahydro-1,2-oxazino-[5,6-b]-indoles. Journal of Natural Products. 52: 332-6. PMID 2746259  0.161
2010 CALDERON SN, ROTHMAN RB, PORRECA F, FLIPPEN-ANDERSON JL, MCNUTT RW, XU H, SMITH LE, BILSKY EJ, DAVIS P, RICE KC. ChemInform Abstract: Probes for Narcotic Receptor Mediated Phenomena. Part 19. Synthesis of (+)-4-((αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)- 3-methoxybenzyl)-N,N-diethylbenzamide (SNC 80): A Highly Selective, Nonpeptide δ Opioid Receptor Agonis Cheminform. 25: no-no. DOI: 10.1002/CHIN.199448177  0.16
1998 Kozikowski AP, Araldi GL, Flippen-Anderson J, George C, Pshenichkin S, Surina E, Wroblewski J. Synthesis and metabotropic glutamate receptor activity of a 2- aminobicyclo[3.2.0]Heptane-2,5-dicarboxylic acid, a molecule possessing an extended glutamate conformation Bioorganic and Medicinal Chemistry Letters. 8: 925-930. PMID 9871513 DOI: 10.1016/S0960-894X(98)00146-2  0.16
2003 Zhao S, Liao X, Wang T, Flippen-Anderson J, Cook JM. The enantiospecific, stereospecific total synthesis of the ring-A oxygenated sarpagine indole alkaloids (+)-majvinine, (+)-10-methoxyaffinisine, and (+)-N(a)-methylsarpagine, as well as the total synthesis of the alstonia bisindole alkaloid macralstonidine. The Journal of Organic Chemistry. 68: 6279-95. PMID 12895062 DOI: 10.1021/Jo030055U  0.158
2001 Zhang J, Flippen-Anderson JL, Kozikowski AP. A tandem Michael addition ring-closure route to the metabotropic receptor ligand α-(hydroxymethyl)glutamic acid and its γ-alkylated derivatives Journal of Organic Chemistry. 66: 7555-7559. PMID 11681981 DOI: 10.1021/jo010626n  0.156
1990 Lin AJ, Li LQ, Klayman DL, George CF, Flippen-Anderson JL. Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 3. Aromatic amine analogues. Journal of Medicinal Chemistry. 33: 2610-4. PMID 2202831 DOI: 10.1021/jm00171a041  0.153
2010 BERTHA CM, ELLIS M, FLIPPEN-ANDERSON JL, PORRECA F, ROTHMAN RB, DAVIS P, XU H, BECKETTS K, RICE KC. ChemInform Abstract: Probes for Narcotic Receptor-Mediated Phenomena. Part 21. Novel Derivatives of 3-(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-6H- azocino(4,5-b)indol-6-yl)phenols with Improved δ Opioid Receptor Selectivity. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199635165  0.151
1987 Yu QS, Brossi A, Flippen-Anderson JL. S-configuration of (+)-primaquine by X-ray analysis of the urea obtained with R-(+)-1-phenylethylisocyanate. Febs Letters. 221: 325-6. PMID 3622772 DOI: 10.1016/0014-5793(87)80949-3  0.149
2002 Appell M, Dunn WJ, Reith ME, Miller L, Flippen-Anderson JL. An analysis of the binding of cocaine analogues to the monoamine transporters using tensor decomposition 3-d QSAR. Bioorganic & Medicinal Chemistry. 10: 1197-206. PMID 11886784  0.147
1988 MARCHAND AP, ANNAPURNA GS, VIDYASAGAR V, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, AMMON HL. ChemInform Abstract: Synthesis of Nitro-Substituted 2,3,4,8-Tetraphenylpentacyclo-(5.3.0.02,5.03,9.04,8)decanes. Cheminform. 19. DOI: 10.1002/CHIN.198813121  0.146
1982 BUCHS P, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: (E)-5-HYDROXYPYRROLIZIDIN-3-ONE: VERSATILE SYNTHON FOR THE SYNTHESIS OF 5-SUBSTITUTED 2-PYRROLIDONES AND (Z)-3-ALKYLPYRROLIZIDINES Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198235198  0.146
2001 Saavedra JE, Srinivasan A, Bonifant CL, Chu J, Shanklin AP, Flippen-Anderson JL, Rice WG, Turpin JA, Davies KM, Keefer LK. The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions. The Journal of Organic Chemistry. 66: 3090-8. PMID 11325274 DOI: 10.1021/Jo0016529  0.145
2001 Flippen-Anderson JL, Axenrod T, Qi L, Gilardi RD. 1,5-Di-tert-butyl-3-hydroxy-7-methylene-1-azonia-5-azacyclooctane iodide Acta Crystallographica Section E Structure Reports Online. 57: o1147-o1148. DOI: 10.1107/S1600536801018190  0.145
2010 KOZIKOWSKI AP, ARALDI GL, FLIPPEN-ANDERSON J, GEORGE C, PSHENICHKIN S, SURINA E, WROBLEWSKI J. ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Activity of a 2-Aminobicyclo[3.2.0]heptane-2,5-dicarboxylic Acid, a Molecule Possessing an Extended Glutamate Conformation. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199834228  0.145
1989 Itoh Y, Brossi A, Hamel E, Flippen-Anderson JL, George C. Colchicine models: Synthesis and Antitubulin Activity of 2?-Monosubstituted and 2?, 5-Disubstituted 2,3,4,4?-Tetramethoxy-1,1?-biphenyls. Synthesis of 4,4?, 5?, 6?-tetramethoxy-1,1?-biphenyl-2,3?-dicarboxylic acid Helvetica Chimica Acta. 72: 196-204. DOI: 10.1002/Hlca.19890720203  0.143
2003 Chen W, Wu H, Bernard D, Metcalf MD, Deschamps JR, Flippen-Anderson JL, MacKerell AD, Coop A. Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine. The Journal of Organic Chemistry. 68: 1929-32. PMID 12608812 DOI: 10.1021/Jo020704M  0.142
1988 KEEFER LK, HRABIE JA, OHANNESIAN L, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: A Symmetrically Hydrogen-Bonded “Binitrosamine Cation” Produced on Protonation of N-Nitrosopyrrolidine Cheminform. 19. DOI: 10.1002/CHIN.198838063  0.142
1988 Keefer LK, Hrabie JA, Ohannesian L, Flippen-Anderson JL, George C. A symmetrically hydrogen-bonded binitrosamine cation produced on protonation of N-nitrosopyrrolidine Journal of the American Chemical Society. 110: 3701-3702. DOI: 10.1021/Ja00219A078  0.141
1987 Karle IL, Flippen-Anderson J, Sukumar M, Balaram P. Parallel packing of alpha-helices in crystals of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-Ala-Aib-Pro-Aib-Pro-Phe-OMe·4H2O·2CH3OH Acta Crystallographica Section a Foundations of Crystallography. 43: C51-C51. DOI: 10.1107/S0108767387084149  0.141
1999 Linders JT, Flippen-Anderson JL, George CF, Rice KC. An expedient synthesis of 9-keto-2-methyl-5-(dimethoxyphenyl)morphans Tetrahedron Letters. 40: 3905-3908. DOI: 10.1016/S0040-4039(99)00566-3  0.139
1987 Marchand AP, Annapurna GS, Vidyasagar V, Flippen-Anderson JL, Gilardi R, George C, Ammon HL. Synthesis of nitro-substituted 2,3,4,8-tetraphenylpentacyclo[5.3.0.02,5.03,9.04,8]decanes The Journal of Organic Chemistry. 52: 4781-4783. DOI: 10.1021/JO00230A024  0.139
1998 Thomas JB, Mascarella SW, Burgess JP, Xu H, McCullough KB, Rothman RB, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 3149-52. PMID 9873693  0.138
1982 Buchs P, Brossi A, Flippen-Anderson JL. (E)-5-Hydroxypyrrolizidin-3-one: versatile synthon for the synthesis of 5-substituted 2-pyrrolidones and (Z)-3-alkylpyrrolizidines The Journal of Organic Chemistry. 47: 719-723. DOI: 10.1021/JO00343A023  0.136
1989 ITOH Y, BROSSI A, HAMEL E, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Colchicine Models: Synthesis and Antitubulin Activity of 2′-Monosubstituted and 2′,5-Disubstituted 2,3,4,4′-Tetramethoxy-1,1′-biphenyls. Synthesis of 4,4′,5′,6′-Tetramethoxy-1,1′-biphenyl-2,3′-dicarboxylic Acid. Cheminform. 20. DOI: 10.1002/CHIN.198924293  0.136
2000 Axenrod T, Sun J, Das KK, Dave PR, Forohar F, Kaselj M, Trivedi NJ, Gilardi RD, Flippen-Anderson JL. Synthesis and characterization of 5-substituted 1,3-diazacyclohexane derivatives The Journal of Organic Chemistry. 65: 1200-6. PMID 10814072 DOI: 10.1021/jo991524o  0.135
2000 Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, Tella S, Kozikowski AP. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors. Journal of Medicinal Chemistry. 43: 1215-22. PMID 10737754 DOI: 10.1021/jm9905561  0.135
1988 Guy JT, Cooper JC, Gilardi RD, Flippen-Anderson JL, George CF. Transition-metal-promoted oxidation of organic sulfides. Synthesis, characterization, and structure of (.mu.4-oxo)hexakis(.mu.2-chloro)tetrakis(dialkyl sulfoxide)tetracopper(II) Inorganic Chemistry. 27: 635-638. DOI: 10.1021/IC00277A013  0.134
2002 Deschamps JR, Flippen-Anderson JL, George C. Sodium 2-(N-morpholino)ethanesulfonate monohydrate Acta Crystallographica Section E Structure Reports Online. 58: m167-m168. DOI: 10.1107/S160053680200541X  0.134
1984 Flippen-Anderson JL, Gilardi R. Laser dye intermediates: structures of 1,2,3,4-tetrahydroquinolinium-7-sulfonate monohydrate (I), C9H11NO3S.H2O, and twinned 1,2,3,4-tetrahydro-1-methylquinolinium-7-sulfonate (II), C10H13NO3S Acta Crystallographica Section C Crystal Structure Communications. 40: 1065-1068. DOI: 10.1107/S0108270184006806  0.133
1988 MARCHAND AP, JIN P, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE G. ChemInform Abstract: A Novel Rearrangement in a 1,3-Bishomocubyl Ring System. Cheminform. 19. DOI: 10.1002/CHIN.198802135  0.133
1994 Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist. Journal of Medicinal Chemistry. 37: 2125-8. PMID 8035418 DOI: 10.1021/Jm00040A002  0.133
1984 Flippen-Anderson JL, Gilardi R. Structures of three photodimers of 5-fluoro-1,3-dimethyluracil: (I) an anti cyclobutene dimer, C12H13FN4O4; (II) the trans–anti cyclobutane dimer, C12H14F2N4O4; and (III) the cis–syn cyclobutane dimer, C12H14F2N4O4 Acta Crystallographica Section C Crystal Structure Communications. 40: 1957-1960. DOI: 10.1107/S0108270184010210  0.132
2010 Carroll FI, Zhang X, Abraham P, Mascarella SW, Flippen-Anderson J, Deschamps JR. Enantioselective synthesis of strobamine and its analogues Arkivoc. 2010: 96-103. DOI: 10.3998/ark.5550190.0011.409  0.13
2000 Hoepping A, George C, Flippen-Anderson J, Kozikowski AP. Radical cyclization strategies for the formation of ring constrained tricyclic tropane analogues Tetrahedron Letters. 41: 7427-7432. DOI: 10.1016/S0040-4039(00)01288-0  0.13
2010 Ma C, Liu X, Li X, Flippen-Anderson J, Yu S, Cook JM. ChemInform Abstract: Efficient Asymmetric Synthesis of Biologically Important Tryptophan Analogues via a Palladium-Mediated Heteroannulation Reaction. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200146187  0.129
1987 FODOR G, SUSSANGKARN K, MATHELIER H, FANG K, ARNOLD R, FLIPPEN-ANDERSON J, KARLE I. ChemInform Abstract: Stereospecificity of a New Reaction of L-Ascorbic Acid with cis and trans Olefinic 1,4-Dicarbonyl Compounds. Cheminform. 18. DOI: 10.1002/CHIN.198705192  0.126
1988 GUY JTJ, COOPER JC, GILARDI RD, FLIPPEN-ANDERSON JL, GEORGE CFJ. ChemInform Abstract: Transition-Metal-Promoted Oxidation of Organic Sulfides. Synthesis, Characterization, and Structure of (μ4-Oxo)hexakis(μ2-chloro)tetrakis(dialkyl sulfoxide)tetracopper(II). Cheminform. 19. DOI: 10.1002/CHIN.198825304  0.126
1988 MARCHAND AP, ARNEY BEJ, GILARDI R, FLIPPEN-ANDERSON JL. ChemInform Abstract: Lewis Acid Promoter Reaction of Pentacyclo(5.4.0.02,6.03,10.05,9)undecane-8,11-dione with Ethyl Diazoacetate: A Synthetic Entry into the Pentacyclo(6.5.0.04,12.05,10.09,13)tridecane Ring System. Cheminform. 19. DOI: 10.1002/CHIN.198802133  0.124
2010 NIELSEN AT, CHAFIN AP, CHRISTIAN SL, MOORE DW, NADLER MP, NISSAN RA, VANDERAH DJ, GILARDI RD, GEORGE CF, FLIPPEN-ANDERSON JL. ChemInform Abstract: Synthesis of Polyazapolycyclic Caged Polynitramines. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199852187  0.124
1986 HANSEN JF, FLIPPEN-ANDERSON JL. ChemInform Abstract: Stereochemical Assignments for 1-Phenyl-1,2,3-butanetrione 2-Oxime and Related Compounds. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198612112  0.124
2000 Tamiz AP, Smith MP, Enyedy I, Flippen-Anderson J, Zhang M, Johnson KM, Kozikowski AP. Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry Letters. 10: 1681-6. PMID 10937724 DOI: 10.1016/S0960-894X(00)00308-5  0.123
1990 GILARDI R, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: The Structure of T-2 Toxin Cheminform. 21. DOI: 10.1002/CHIN.199031315  0.123
1997 Crisma M, Monaco V, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Letters in Peptide Science. 4: 213-218. DOI: 10.1023/A:1008874816982  0.12
2004 Ding K, Flippen-Anderson J, Deschamps JR, Wang S. An efficient synthesis of optically pure (S)-2-functionalized 1,2,3,4-tetrahydroquinoline Tetrahedron Letters. 45: 1027-1029. DOI: 10.1016/J.Tetlet.2003.11.086  0.12
1988 Brossi A, Venugopalan B, Dominguez Gerpe L, Yeh HJ, Flippen-Anderson JL, Buchs P, Luo XD, Milhous W, Peters W. Arteether, a new antimalarial drug: synthesis and antimalarial properties. Journal of Medicinal Chemistry. 31: 645-50. PMID 3279208  0.117
1987 Gilardi R, Flippen-Anderson JL. The tetrasaccharide stachyose Acta Crystallographica Section C Crystal Structure Communications. 43: 806-808. DOI: 10.1107/S0108270187093995  0.115
1996 Crisma M, Bianco A, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Tryptophan-containing polypeptide 3(10)-helices. Side-chain interactions and molecular recognition studies. Advances in Experimental Medicine and Biology. 398: 623-6. PMID 8906336  0.115
1989 MARCHAND AP, DAVE PR, RAJAPAKSA D, ARNEY BEJ, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C. ChemInform Abstract: Synthesis of 4,4,8,8,11,11-Hexanitropentacyclo(5.4.0.02,6.03,10.05,9)-undecane. Cheminform. 20. DOI: 10.1002/CHIN.198943099  0.114
2010 FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Absolute Configuration of (-)-α-Acetylmethadol Hydrochloride. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199305051  0.113
2002 Prakash KR, Tang Y, Kozikowski AP, Flippen-Anderson JL, Knoblach SM, Faden AI. Synthesis and biological activity of novel neuroprotective diketopiperazines. Bioorganic & Medicinal Chemistry. 10: 3043-8. PMID 12110327 DOI: 10.1016/S0968-0896(02)00132-3  0.113
1990 FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, DAVE PR. ChemInform Abstract: Structure of a Dimer Ketone Formed via Fe(CO)5-Promoted Coupling of 7-(p-Cyanophenoxy)norbornadiene to Carbon Monoxide. Cheminform. 21. DOI: 10.1002/CHIN.199035050  0.112
2008 Henrick K, Feng Z, Bluhm WF, Dimitropoulos D, Doreleijers JF, Dutta S, Flippen-Anderson JL, Ionides J, Kamada C, Krissinel E, Lawson CL, Markley JL, Nakamura H, Newman R, Shimizu Y, et al. Remediation of the protein data bank archive. Nucleic Acids Research. 36: D426-33. PMID 18073189 DOI: 10.1093/Nar/Gkm937  0.112
2001 Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP. Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors. Journal of Medicinal Chemistry. 44: 1615-22. PMID 11334571 DOI: 10.1021/jm000552s  0.111
1980 Flippen-Anderson JL, Karle I, Huisgen R, Reißig H. Trimerisierung eines Azomethin-imins durch drei aufeinanderfolgende 1,3-dipolare Cycloadditionen Angewandte Chemie. 92: 936-937. DOI: 10.1002/Ange.19800921114  0.111
1991 Paciorek KJL, Nakahara JH, Hoferkamp LA, George C, Flippen-Anderson JL, Gilardi R, Schmidt WR. Reactions of tris[bis(trimethylsilyl)amino]aluminum with ammonia and pyrolysis studies Chemistry of Materials. 3: 82-87. DOI: 10.1021/Cm00013A021  0.11
2000 Zhao L, Johnson KM, Zhang M, Flippen-Anderson J, Kozikowski AP. Chemical synthesis and pharmacology of 6- and 7-hydroxylated 2-carbomethoxy-3-(p-tolyl)tropanes: antagonism of cocaine's locomotor stimulant effects. Journal of Medicinal Chemistry. 43: 3283-94. PMID 10966747 DOI: 10.1021/jm000141b  0.11
1990 Pramod K, Eaton PE, Gilardi R, Flippen-Anderson JL. Regiospecific oxidation of binor S and acid-catalyzed rearrangement of the product to the first example of a pentacyclo[6.6.0.05,14.07,12.09,13]tetradecane Journal of Organic Chemistry. 55: 6105-6107. DOI: 10.1021/Jo00312A014  0.11
1996 Yamada K, Rice KC, Flippen-Anderson JL, Eissenstat MA, Ward SJ, Johnson MR, Howlett AC. (Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor. Journal of Medicinal Chemistry. 39: 1967-74. PMID 8642555 DOI: 10.1021/jm950932r  0.11
1998 Nielsen AT, Chafin AP, Christian SL, Moore DW, Nadler MP, Nissan RA, Vanderah DJ, Gilardi RD, George CF, Flippen-Anderson JL. Synthesis of polyazapolycyclic caged polynitramines Tetrahedron. 54: 11793-11812. DOI: 10.1016/S0040-4020(98)83040-8  0.109
2001 Flippen-Anderson JL, Axenrod T, Sun J, Gilardi RD. 3,7-Di-tert-butyl-1,5-dinitro-3,7-diazabicyclo[3.3.1]nonane Acta Crystallographica Section E Structure Reports Online. 57: o1128-o1129. DOI: 10.1107/S1600536801018153  0.109
1988 CHRZANOWSKA M, SCHOENENBERGER B, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: Mammalian Alkaloids: Configurations of Optically Active Salsoline- and 3′,4′-Dideoxynorlaudanosoline-1-carboxylic Acids. Cheminform. 19. DOI: 10.1002/CHIN.198805346  0.108
1986 Schönenberger B, Brossi A, George C, Flippen-Anderson JL. Preparation of Optically Active Secondary Amines by Thermal Decomposition of (Methylbenzyl)urea Analogs: Absolute Configuration of (+)- and (−)-Mecamylamine. Preliminary Communication Helvetica Chimica Acta. 69: 283-287. DOI: 10.1002/Hlca.19860690205  0.108
2006 Kozikowski AP, Zhao L, Zhang A, Wang CZ, Flippen-Anderson J, Johnson KM. Structural remodeling of cocaine: design and synthesis of trisubstituted cyclopropanes as selective serotonin reuptake inhibitors. Chemmedchem. 1: 58-65. PMID 16892336 DOI: 10.1002/cmdc.200500016  0.107
2006 Kozikowski AP, Zhao L, Zhang A, Wang CZ, Flippen-Anderson J, Johnson KM. Structural Remodeling of Cocaine: Design and Synthesis of Trisubstituted Cyclopropanes as Selective Serotonin Reuptake Inhibitors. Cheminform. 37. DOI: 10.1002/CHIN.200622196  0.107
2010 OLAH GA, SASSAMAN MB, ZUANIC M, RAO CB, PRAKASH GKS, GILARDI R, FLIPPEN-ANDERSON J, GEORGE C. ChemInform Abstract: Considered Synthetic Method and Reactions. Part 165. One-Step Preparation of Hydrazinium Nitrates from Tertiary Amines and Azaarenes with H2N-O-SO3H/Ba(NO3)2 and Conversion to Energetic Amine-Nitroimides. Cheminform. 23: no-no. DOI: 10.1002/chin.199233136  0.107
1992 Olah GA, Sassaman MB, Zuanic M, Rao CB, Prakash GKS, Gilardi R, Flippen-Anderson J, George C. Considered synthetic methods and reactions. Part 165. One-step preparation of hydrazinium nitrates from tertiary amines and azaarenes with hydroxylamine-O-sulfonic acid/barium nitrate/barium oxide and conversion to energetic amine-nitroimides The Journal of Organic Chemistry. 57: 1585-1588. DOI: 10.1021/Jo00031A046  0.105
2003 Zhao S, Liao X, Wang T, Flippen-Anderson J, Cook JM. The Enantiospecific, Stereospecific Total Synthesis of the Ring-A Oxygenated Sarpagine Indole Alkaloids (+)-Majvinine (Ia), (+)-10-Methoxyaffinisine (Ib), and (+)-Na-Methylsarpagine (Ic), as Well as the Total Synthesis of the Alstonia Bisindole Alkaloid Macralstonidine (II). Cheminform. 34. DOI: 10.1002/CHIN.200349193  0.105
2010 VEDACHALAM M, RAMAKRISHNAN VT, BOYER JH, DAGLEY IJ, NELSON KA, ADOLPH HG, GILARDI R, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: Facile Synthesis and Nitration of cis-syn-cis-2,6-Dioxodecahydro-1H,5H- diimidazo(4,5-b:4′,5′-e)pyrazine. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199139179  0.105
2001 Deschamps JR, George C, Flippen-Anderson JL, Spencer G. A newCryptocaryalactone Acta Crystallographica Section E Structure Reports Online. 57: o648-o649. DOI: 10.1107/S1600536801010273  0.104
2010 Jarvis BB, Taha Çömezoglu F, Lee Y, Flippen-Anderson JL, Gilardi RD, George CF. Novel Macrocyclic Trichothecenes from Myrothecium Roridum Bulletin Des SociéTéS Chimiques Belges. 95: 681-697. DOI: 10.1002/BSCB.19860950901  0.103
1990 NIELSEN AT, NISSAN RA, VANDERAH DJ, COON CL, GILARDI RD, GEORGE CFJ, FLIPPEN-ANDERSON JL. ChemInform Abstract: Polyazapolycyclics by Condensation of Aldehydes with Amines. Part 2. Formation of 2,4,6,8,10,12-Hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo-(5.5.0.05,9.03,11)dodecanes from Glyoxal and Benzylamines. Cheminform. 21. DOI: 10.1002/CHIN.199032201  0.103
2017 Burley SK, Gabanyi MJ, Sala R, Westbrook JD, Flippen-Anderson JL, Deshmukh I, Berman HM. BioSync: an online resource for X-ray facilities worldwide Acta Crystallographica Section a Foundations and Advances. 73: C1216-C1216. DOI: 10.1107/S2053273317083589  0.101
1987 Chrzanowska M, Schönenberger B, Brossi A, Flippen-Anderson JL. Mammalian Alkaloids: Configurations of Optically Active Salsoline- and 3′,4′-Dideoxynorlaudanosoline-1-carboxylic Acids Helvetica Chimica Acta. 70: 1721-1731. DOI: 10.1002/HLCA.19870700707  0.101
2000 Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. Journal of Medicinal Chemistry. 43: 4868-76. PMID 11123996 DOI: 10.1021/Jm000329V  0.101
1984 SCHMIDHAMMER H, BROSSI A, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: APOMORPHINANS FROM ISOQUINOLINES: GREWE CYCLIZATION OF 1-(2-HYDROXYBENZYL)-N-METHYLOCTAHYDROISOQUINOLINE AND ITS O-METHYL ETHER Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198411066  0.099
2010 DAGLEY IJ, FLIPPEN-ANDERSON JL. ChemInform Abstract: Synthesis of Cyclic Nitramines from Products of the Cyclocondensation Reaction of Guanidine with 2,3,5,6-Tetrahydroxypiperazine-1,4- dicarbaldehyde. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199515195  0.099
2005 Deshpande N, Addess KJ, Bluhm WF, Merino-Ott JC, Townsend-Merino W, Zhang Q, Knezevich C, Xie L, Chen L, Feng Z, Green RK, Flippen-Anderson JL, Westbrook J, Berman HM, Bourne PE. The RCSB Protein Databa Bank: A redesigned query system and relational database based on the mmCIF schema Nucleic Acids Research. 33: D233-D237. PMID 15608185 DOI: 10.1093/Nar/Gki057  0.099
1990 MARCHAND AP, ANNAPURNA P, TAYLOR RW, SIMMONS DL, WATSON WH, NAGL A, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C. ChemInform Abstract: Unusual Behavior of 3,4:10,11-Bis(2′,3′-quinolino)tricyclo(6.3.0.02,6)undecane Upon Attempted Monoprotonation with Triflic Acid. Cheminform. 21. DOI: 10.1002/CHIN.199047144  0.098
1981 Schwab AW, Gilardi RD, Flippen-anderson JL. CONFIGURATION OF OCTADECYL TETRASULFIDE Phosphorus and Sulfur and the Related Elements. 10: 123-126. DOI: 10.1080/03086648108078280  0.095
2010 BAUM K, BIGELOW SS, NGUYEN NV, ARCHIBALD TG, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Synthesis and Reactions of 1,1-Diiododinitroethylene. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199225047  0.094
2006 Bourne PE, Bluhm WF, Deshpande N, Zhang Q, Berman HM, Flippen-Anderson JL. The research collaboratory for structural bioinformatics protein data bank Comprehensive Medicinal Chemistry Ii. 3: 373-388.  0.094
2010 FLIPPEN-ANDERSON JL, GILARDI RD, PITT AM, WILSON WS. ChemInform Abstract: Synthesis and Explosive Properties of Benzotriazoles. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199223168  0.094
2003 Cao H, Flippen-Anderson J, Cook JM. The synthesis of a dicyclopenta[a,e]pentalene via a molybdenum hexacarbonyl-mediated tandem allenic Pauson-Khand reaction. Journal of the American Chemical Society. 125: 3230-1. PMID 12630875 DOI: 10.1021/Ja021159+  0.091
2010 BRZOSTOWSKA M, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: Chiral Prodyes: Synthesis and Full Characterization of (S)-1- Phenylethylamides of the Optically Active O-Methyldihydrofluoresceins. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199204178  0.091
2010 BAUM K, ARCHIBALD TG, TZENG D, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Synthesis and Properties of 1,2-Difluorodinitroethylene. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199131113  0.091
2004 Yu H, Kim IJ, Folk JE, Tian X, Rothman RB, Baumann MH, Dersch CM, Flippen-Anderson JL, Parrish D, Jacobson AE, Rice KC. Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters. Journal of Medicinal Chemistry. 47: 2624-34. PMID 15115403 DOI: 10.1021/Jm0305873  0.09
1985 West DX, Ahrweiler PM, Ertem G, Scovill JP, Klayman DL, Flippen-Anderson JL, Gilardi R, George C, Pannell LK. Iron(III) complexes of some thiosemicarbazones derived from 2-acetylpyridine, its 6-methyl derivative and itsN-oxide Transition Metal Chemistry. 10: 264-270. DOI: 10.1007/Bf00621084  0.09
2005 Deng H, Gifford AN, Zvonok AM, Cui G, Li X, Fan P, Deschamps JR, Flippen-Anderson JL, Gatley SJ, Makriyannis A. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. Journal of Medicinal Chemistry. 48: 6386-92. PMID 16190764 DOI: 10.1021/Jm050135L  0.089
1983 Schmidhammer H, Brossi A, Flippen-Anderson JL, Gilardi R. Apomorphinans from Isoquinolines:Grewe cyclization of 1-(2-hydroxybenzyl)-N-methyloctahydroisoquinoline and itsO-methyl ether Helvetica Chimica Acta. 66: 2437-2442. DOI: 10.1002/HLCA.19830660807  0.088
2004 Yu J, Wang T, Liu X, Deschamps J, Flippen-Anderson J, Liao X, Cook JM. General Approach for the Synthesis of Sarpagine Indole Alkaloids. Enantiospecific Total Synthesis of (+)-Vellosimine (Ia), (+)-Normacusine B (Ib), (-)-Alkaloid Q3 (II), (-)-Panarine (III), (+)-Na-Methylvellosimine (IVa), and (+)-Na-Methyl-16-epipericyclivine (IVb). Cheminform. 35. DOI: 10.1002/chin.200406169  0.088
1985 KEREKES P, BROSSI A, FLIPPEN-ANDERSON JL, CHIGNELL CF. ChemInform Abstract: ESTERS OF 1-O-DEMETHYLTHIOCOLCHICINES: FORMATION OF ISOMERS IN CHLOROFORM SOLUTION Chemischer Informationsdienst. 16. DOI: 10.1002/CHIN.198535083  0.086
1990 Nielsen AT, Nissan RA, Vanderah DJ, Coon CL, Gilardi RD, George CF, Flippen-Anderson J. Polyazapolycyclics by condensation of aldehydes with amines. 2. Formation of 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05.9.03,11]dodecanes from glyoxal and benzylamines The Journal of Organic Chemistry. 55: 1459-1466. DOI: 10.1021/JO00292A015  0.084
1986 SCHOENENBERGER B, BROSSI A, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: Preparation of Optically Active Secondary Amines by Thermal Decomposition of (Methylbenzyl)urea Analogs: Absolute Configuration of (+)- and (-)-Mecamylamine. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198624331  0.083
2001 Gilardi RD, Axenrod T, Sun J, Flippen-Anderson JL. 1,3,5,7-tetranitro-3,7-diazabicyclo[3.3.1]nonane Acta Crystallographica Section E Structure Reports Online. 57: o1107-o1108. DOI: 10.1107/S1600536801017780  0.083
1991 Vedachalam M, Ramakrishnan VT, Boyer JH, Dagley IJ, Nelson KA, Adolph HG, Gilardi R, George C, Flippen-Anderson JL. Facile synthesis and nitration of cis-syn-cis-2,6-dioxodecahydro-1H,5H-diimidazo[4,5-b:4',5'-e]pyrazine The Journal of Organic Chemistry. 56: 3413-3419. DOI: 10.1021/JO00010A043  0.082
1985 Kerekes P, Brossi A, Flippen-Anderson JL, Chignell CF. Esters of 1-O-Demethylthiocolchicines: Formation of Isomers in Chloroform Solution Helvetica Chimica Acta. 68: 571-580. DOI: 10.1002/HLCA.19850680306  0.075
1991 Baum K, Archibald TG, Tzeng D, Gilardi R, Flippen-Anderson JL, George C. Synthesis and properties of 1,2-difluorodinitroethylene The Journal of Organic Chemistry. 56: 537-539. DOI: 10.1021/JO00002A011  0.074
1998 Smith MP, Johnson KM, Zhang M, Flippen-Anderson JL, Kozikowski AP. Tuning the selectivity of monoamine transporter inhibitors by the stereochemistry of the nitrogen lone pair [2] Journal of the American Chemical Society. 120: 9072-9073. DOI: 10.1021/ja981423s  0.072
2000 Tamiz AP, Smith MP, Enyedy I, Flippen-Anderson J, Zhang M, Johnson KM, Kozikowski AP. ChemInform Abstract: Synthesis and Biological Evaluation of 1-Azabicyclo[3.2.1]octanes: New Dopamine Transporter Inhibitors. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200044172  0.072
2010 BAUM K, NGUYEN NV, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Nitration of 1,1-Diamino-2,2-dinitroethylenes. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199245118  0.072
2010 SAAVEDRA JE, DUNAMS TM, FLIPPEN-ANDERSON JL, KEEFER LK. ChemInform Abstract: Secondary Amine/Nitric Oxide Complex Ions, R2N(N(O)NO)-. O- Functionalization Chemistry. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199310166  0.069
1980 Flippen-Anderson JL, Karle I, Huisgen R, Reissig H. Trimerization of an Azomethine Imine by Three Successive 1,3-Dipolar Cycloaddition Reactions Angewandte Chemie International Edition in English. 19: 906-907. DOI: 10.1002/Anie.198009061  0.069
2002 Gilardi R, Flippen-Anderson JL, Evans R. cis-2,4,6,8-Tetranitro-1H,5H-2,4,6,8-tetraazabicyclo[3.3.0]octane, the energetic compound `bicyclo-HMX' Acta Crystallographica Section E Structure Reports Online. 58: o972-o974. DOI: 10.1107/S1600536802013582  0.068
2003 Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, Farkas T, Johnson KM, Wang S. 2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry. 11: 1123-36. PMID 12614900 DOI: 10.1016/S0968-0896(02)00450-9  0.067
2000 Sakamuri S, George C, Flippen-Anderson J, Kozikowski AP. Synthesis of novel spirocyclic cocaine analogs using the Suzuki coupling Tetrahedron Letters. 41: 2055-2058. DOI: 10.1016/S0040-4039(00)00113-1  0.065
1984 LUO X, YEH HJC, BROSSI A, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: THE CHEMISTRY OF DRUGS. PART IV. CONFIGURATIONS OF ANTIMALARIALS DERIVED FROM M QINGHAOSU: DIHYDROQINGHAOSU, ARTEMETHER, AND ARTESUNIC ACID Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198452374  0.065
2001 Qiao L, Zhao LY, Rong SB, Wu XW, Wang S, Fujii T, Kazanietz MG, Rauser L, Savage J, Roth BL, Flippen-Anderson J, Kozikowski AP. Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth. Bioorganic & Medicinal Chemistry Letters. 11: 955-9. PMID 11327599 DOI: 10.1016/S0960-894X(01)00097-X  0.064
1984 Luo X, Yeh HJC, Brossi A, Flippen-Anderson JL, Gillardi R. The chemistry of drugs part IV, Configurations of antimalarials derived from qinghaosu: Dihydroqingyhaosu, artemether, and artesunic acid Helvetica Chimica Acta. 67: 1515-1522. DOI: 10.1002/HLCA.19840670615  0.064
1992 Saavedra JE, Dunams TM, Flippen-Anderson JL, Keefer LK. Secondary amine/nitric oxide complex ions, R2N[N(O)NO]-. O-Functionalization chemistry The Journal of Organic Chemistry. 57: 6134-6138. DOI: 10.1021/JO00049A017  0.063
1989 SRIVASTAVA S, MARCHAND AP, VIDYASAGAR V, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, ZACHWIEJA Z, LE NOBLE WJ. ChemInform Abstract: Pressure Effect on the Product Distribution in Competing Reactions: Formation of a Bis Diels-Alder Adduct via an Aromatizable Intermediate. Cheminform. 20. DOI: 10.1002/CHIN.198929062  0.061
2002 Flippen-Anderson JL, Deschamps JR, Brossi A, Greig NH. 2-Hydroxybenzoic acid salt of physostigmine Acta Crystallographica Section E Structure Reports Online. 58: o853-o855. DOI: 10.1107/S1600536802012278  0.058
1980 THOMPSON MJ, MANDAVA N, FLIPPEN-ANDERSON JL, WORLEY JF, DUTKY SR, ROBBINS WE, LUSBY W. ChemInform Abstract: SYNTHESIS OF BRASSINO STEROIDS: NEW PLANT-GROWTH-PROMOTING STEROIDS Chemischer Informationsdienst. 11. DOI: 10.1002/CHIN.198018298  0.057
1991 Scovill JP, Klayman DL, Flippen-anderson JL, Gilardi R. 1,3,4-THIADIAZOLES FROM THIOSEMICARBAZIDES Phosphorus, Sulfur, and Silicon and the Related Elements. 63: 273-281. DOI: 10.1080/10426509108036830  0.053
1992 Chaykovsky M, Koppes WM, Russell TP, Gilardi R, George C, Flippen-Anderson JL. The isolation of a bi(2,4,6,8-tetraazabicyclo[3.3.0]octane) from the reaction of glyoxal with benzylamine The Journal of Organic Chemistry. 57: 4295-4297. DOI: 10.1021/Jo00041A044  0.051
1989 Srivastava S, Marchand AP, Vidyasagar V, Flippen-Anderson JL, Gilardi R, George C, Zachwieja Z, Le Noble WJ. Pressure effect on the product distribution in competing reactions: formation of a bis Diels-Alder adduct via an aromatizable intermediate The Journal of Organic Chemistry. 54: 247-249. DOI: 10.1021/JO00262A052  0.051
2002 Deschamps JR, Flippen-Anderson JL, George C. The search for a better analgesic Acta Crystallographica Section a Foundations of Crystallography. 58: c36-c36. DOI: 10.1107/S0108767302086543  0.049
1990 MORIARTY RM, KHOSROWSHAHI JS, MILLER RS, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: Free-Radical Arylation of Cubane Using Cubyl Lead Acylates. Cheminform. 21. DOI: 10.1002/CHIN.199011132  0.046
1979 Thompson MJ, Mandava N, Flippen-Anderson JL, Worley JF, Dutky SR, Robbins WE, Lusby W. Synthesis of brassino steroids: new plant-growth-promoting steroids The Journal of Organic Chemistry. 44: 5002-5004. DOI: 10.1021/jo00394a066  0.046
1985 Jarvis BB, Lee YW, Yatawara CS, Mazzocchi DB, Flippen-Anderson JL, Gilardi R, George C. 7 alpha-hydroxytrichodermol, a new trichothecene from Myrothecium roridum. Applied and Environmental Microbiology. 50: 1225-8. PMID 4091555 DOI: 10.1128/Aem.50.5.1225-1228.1985  0.043
2003 Flippen-Anderson JL, George C, Deschamps JR. Molecular approaches to treatments for cocaine abuse Journal of Molecular Structure. 647: 259-267. DOI: 10.1016/S0022-2860(02)00532-X  0.038
2001 Zheng T, Flippen-Anderson J, Yu P, Wang T, Mirghani R, Cook JM. Stereocontrolled conversion of quinine into 10(R),11-dihydroxydihydroquinine via the sharpless osmylation process. The Journal of Organic Chemistry. 66: 1509-11. PMID 11312991 DOI: 10.1021/Jo0015321  0.032
2002 Gilardi RD, Flippen-Anderson JL. Twins and multiple polymorphs occurring in energetic organic materials Acta Crystallographica Section a Foundations of Crystallography. 58: c232-c232. DOI: 10.1107/S0108767302094308  0.032
1985 Gilardi R, Flippen-Anderson JL. Synthetic high-pressure lubricants: dioctadecyl trisulfide (I), C36H74S3, and dioctadecyl tetrasulfide (II), C36H74S4 Acta Crystallographica Section C Crystal Structure Communications. 41: 72-76. DOI: 10.1107/S0108270185002827  0.031
2002 Flippen-Anderson J, Deschamps JR, George C. Data quality and the modern CCD detector Acta Crystallographica Section a Foundations of Crystallography. 58: c260-c260. DOI: 10.1107/S0108767302095399  0.012
1986 Pavanand K, Nutakul W, Dechatiwongse T, Yoshihira K, Yongvanitchit K, Scovill JP, Flippen-Anderson JL, Gilardi R, George C, Kanchanapee P. In vitro antimalarial activity of Brucea javanica against multi-drug resistant Plasmodium falciparum. Planta Medica. 108-11. PMID 3523552  0.01
1982 Flippen-Anderson JL, Mills FD. Stereochemistry of a complex diindenopyradione Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 38: 495-498. DOI: 10.1107/S0567740882003264  0.01
1981 Flippen-Anderson JL, Gilardi R. Structure–activity relationships in brassino steroids Acta Crystallographica Section a Foundations of Crystallography. 37: C57-C57. DOI: 10.1107/S0108767381097869  0.01
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