Year |
Citation |
Score |
2005 |
Crisma M, Deschamps JR, George C, Flippen-Anderson JL, Kaptein B, Broxterman QB, Moretto A, Oancea S, Jost M, Formaggio F, Toniolo C. A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 564-79. PMID 15885116 DOI: 10.1111/J.1399-3011.2005.00258.X |
0.321 |
|
2002 |
Bryant SD, George C, Flippen-Anderson JL, Deschamps JR, Salvadori S, Balboni G, Guerrini R, Lazarus LH. Crystal structures of dipeptides containing the Dmt-Tic pharmacophore Journal of Medicinal Chemistry. 45: 5506-5513. PMID 12459018 DOI: 10.1021/Jm020330P |
0.416 |
|
2002 |
Flippen-Anderson JL, Deschamps JR, George C, Hruby VJ, Misicka A, Lipkowski AW. Crystal structure of biphalin sulfate: a multireceptor opioid peptide. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 123-33. PMID 11985706 DOI: 10.1034/J.1399-3011.2002.01967.X |
0.33 |
|
2001 |
Deschamps JR, Flippen-Anderson JL, Brine GA, Hayes JP, George C. Boc-tyrosyl-D-alanyl-glycyl-N-methyl-phenylalanyl-O-methyl-methionine hydrate: a protected analog of metkephamid Acta Crystallographica Section E Structure Reports Online. 58: o13-o15. DOI: 10.1107/S1600536801020475 |
0.328 |
|
1998 |
Deschamps JR, George C, Flippen-Anderson JL. The relationship between structure and activity among opioid peptides Letters in Peptide Science. 5: 337-340. DOI: 10.1007/Bf02443482 |
0.335 |
|
1997 |
Deschamps JR, Flippen-Anderson JL, Moore C, Cudney R, George C. Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-hydrate and tyrosyl-D-tetrahydroisoquinoline-3-carboxamide hydrate. Acta Crystallographica. Section C, Crystal Structure Communications. 53: 1478-82. PMID 9362554 DOI: 10.1107/S0108270197006975 |
0.306 |
|
1997 |
Gilardi R, Flippen-Anderson J, George C, Butcher RJ. A New Class of Flexible Energetic Salts: The Crystal Structures of the Ammonium, Lithium, Potassium, and Cesium Salts of Dinitramide Journal of the American Chemical Society. 119: 9411-9416. DOI: 10.1021/Ja9709280 |
0.335 |
|
1996 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Effects of end group and aggregation on helix conformation: crystal structure of Ac-(Aib-Val-Ala-Leu)2-Aib-OMe. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 106-16. PMID 9225250 DOI: 10.1002/Psc.52 |
0.363 |
|
1996 |
George C, Flippen-Anderson JL, Bianco A, Crisma M, Formaggio F, Toniolo C. Crystallographic characterization of tryptophan-containing peptide 3(10)-helices. Peptide Research. 9: 315-21. PMID 9048426 |
0.33 |
|
1996 |
Collins N, Flippen-Anderson JL, Haaseth RC, Deschamps JR, George C, Kövér K, Hruby VJ. Conformational Determinants of Agonist versus Antagonist Properties of [d-Pen2,d-Pen5]Enkephalin (DPDPE) Analogs at Opioid Receptors. Comparison of X-ray Crystallographic Structure, Solution1H NMR Data, and Molecular Dynamic Simulations of [l-Ala3]DPDPE and [d-Ala3]DPDPE Journal of the American Chemical Society. 118: 2143-2152. DOI: 10.1021/Ja9531081 |
0.343 |
|
1996 |
Butcher RJ, Gilardi RD, George C, Flippen-Anderson J. Distortions in nitramine substituted cubanes: The structures of N,N′-dinitro-1,4-diaminocubane, N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane, and 1,2,4,7-tetrakis(N-methoxycarbonylnitramino)cubane Journal of Chemical Crystallography. 26: 381-388. DOI: 10.1007/Bf01665815 |
0.322 |
|
1994 |
Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Conformation of the flexible bent helix of Leu1-zervamicin in crystal C and a possible gating action for ion passage. Biopolymers. 34: 721-35. PMID 8025219 DOI: 10.1002/Bip.360340605 |
0.339 |
|
1994 |
Flippen-Anderson JL, Deschamps JR, Clifford George, Ward KB, Houghten R. Crystal structure of deltakephalin: A δ-selective opioid peptide with a novel β-bend-like conformation International Journal of Peptide and Protein Research. 44: 97-104. PMID 7982763 DOI: 10.1111/J.1399-3011.1994.Tb00563.X |
0.426 |
|
1994 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Hydration and distortion of peptide helices in crystals. Alpha-helical structure of a dodecapeptide, Boc-(Ala-Leu-Aib)4-OMe. International Journal of Peptide and Protein Research. 44: 491-8. PMID 7896509 DOI: 10.1111/J.1399-3011.1994.Tb00187.X |
0.332 |
|
1994 |
Lomize AL, Flippen-Anderson JL, George C, Mosberg HI. Conformational analysis of the δ receptor-selective, cyclic opioid peptide, Tyr-cyclo[D-Cys-Phe-D-Pen]OH (JOM-13). Comparison of X-ray crystallographic structures, molecular mechanics simulations, and 1H NMR data Journal of the American Chemical Society. 116. DOI: 10.1021/Ja00081A001 |
0.308 |
|
1994 |
Flippen-Anderson JL, George C, Deschamps JR, Reddy PA, Lewin AH, Brine GA. X-ray structures of the ? opioid antagonist TIPP and a protected derivative of the ? opioid antagonist ICI 174,864 Letters in Peptide Science. 1: 107-115. DOI: 10.1007/Bf00128528 |
0.443 |
|
1993 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Accommodation of a D-Phe residue into a right-handed 3(10)-helix: structure of Boc-D-Phe-(Aib)4-Gly-L-Leu-(Aib)2-OMe, an analogue of the amino terminal segment of antiamoebins and emerimicins. Biopolymers. 33: 401-7. PMID 8461451 DOI: 10.1002/Bip.360330308 |
0.319 |
|
1993 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Unfolding of an alpha-helix in peptide crystals by solvation: conformational fragility in a heptapeptide. Biopolymers. 33: 827-37. PMID 8343578 DOI: 10.1002/Bip.360330511 |
0.394 |
|
1993 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Peptide mimics for structural features in proteins. Crystal structures of three heptapeptide helices with a C-terminal 6-->1 hydrogen bond. International Journal of Peptide and Protein Research. 42: 401-10. PMID 8106192 |
0.354 |
|
1992 |
Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Helix packing of leucine-rich peptides: a parallel leucine ladder in the structure of Boc-Aib-Leu-Aib-Aib-Leu-Leu-Leu-Aib-Leu-Aib-OMe. Proteins. 12: 324-30. PMID 1579566 DOI: 10.1002/Prot.340120404 |
0.355 |
|
1992 |
Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Differences in hydration and association of helical Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe.xH2O in two crystalline polymorphs. Journal of Medicinal Chemistry. 35: 3885-9. PMID 1433198 DOI: 10.1021/Jm00099A016 |
0.34 |
|
1991 |
Karle IL, Flippen-Anderson JL, Agarwalla S, Balaram P. Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 88: 5307-11. PMID 1711227 DOI: 10.1073/Pnas.88.12.5307 |
0.354 |
|
1990 |
Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Parallel and antiparallel aggregation of alpha-helices. Crystal structures of two apolar decapeptides X-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe (X = Boc, Ac). International Journal of Peptide and Protein Research. 35: 518-26. PMID 2401593 |
0.334 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Peptide design: influence of a guest Aib-Pro segment on the stereochemistry of an oligo-val sequence--solution conformations and crystal structure of Boc-(Val)2-Aib-Pro-(Val)3-OMe. Biopolymers. 29: 1433-42. PMID 2361154 DOI: 10.1002/Bip.360291010 |
0.367 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: crystal structure of hepta- and octapeptides containing alpha-aminoisobutyric acid. Proteins. 7: 62-73. PMID 2330369 DOI: 10.1002/Prot.340070107 |
0.379 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Synthetic peptide helices in crystals: structure and antiparallel and skewed packing motifs for alpha-helices in two isomeric decapeptides. Biopolymers. 30: 719-31. PMID 2275974 DOI: 10.1002/Bip.360300707 |
0.355 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Parallel zippers formed by alpha-helical peptide columns in crystals of Boc-Aib-Glu(OBzl)-Leu-Aib-Ala-Leu-Aib-Ala-Lys(Z)-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 87: 7921-5. PMID 2236010 DOI: 10.1073/Pnas.87.20.7921 |
0.37 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Helix aggregation in peptide crystals: occurrence of either all parallel or antiparallel packing motifs for alpha-helices in polymorphs of Boc-Aib-Ala-Leu-Ala-Leu-Aib-Leu-Ala-Leu-Aib-OMe. Biopolymers. 29: 1835-45. PMID 2207288 DOI: 10.1002/Bip.360291414 |
0.352 |
|
1989 |
Karle IL, Flippen-Anderson JL, Kishore R, Balaram P. Cystine peptides. Antiparallel beta-sheet conformation of the cyclic biscystine peptide [Boc-Cys-Ala-Cys-NHCH3]2. International Journal of Peptide and Protein Research. 34: 37-41. PMID 2793307 DOI: 10.1111/J.1399-3011.1989.Tb01005.X |
0.302 |
|
1989 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Modular design of synthetic protein mimics. Characterization of the helical conformation of a 13-residue peptide in crystals. Biochemistry. 28: 6696-701. PMID 2790024 DOI: 10.1021/Bi00442A024 |
0.345 |
|
1989 |
Karle IL, Flippen-Anderson JL, Wieland T. Conformational stability of antamanide and analogs. Crystal structure of perhydrosymmetric antamanide, cyclic (-Val-Pro-Pro-Cha-Cha-Val-Pro-Pro-Cha-Cha-). International Journal of Peptide and Protein Research. 33: 422-7. PMID 2777476 |
0.369 |
|
1989 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Solvated helical backbones: x-ray diffraction study of Boc-Ala-Leu-Aib-Ala-Leu-Aib-OMe.H2O. Biopolymers. 28: 773-81. PMID 2706314 DOI: 10.1002/Bip.360280307 |
0.329 |
|
1989 |
Karle IL, Flippen-Anderson JL. Three conformers in a crystal of N-Ac-L-Leu-L-Tyr-OMe. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 791-5. PMID 2604941 DOI: 10.1107/S0108270188014118 |
0.304 |
|
1989 |
Marchand AP, Dave PR, Rajapaksa D, Arney BE, Flippen-Anderson JL, Gilardi R, George C. Synthesis of 4,4,8,8,11,11-hexanitropentacyclo[5.4.0.02,6.03,10.05,9]undecane The Journal of Organic Chemistry. 54: 1769-1771. DOI: 10.1021/Jo00268A056 |
0.314 |
|
1988 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram P. Aggregation studies in crystals of apolar helical peptides: Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe. International Journal of Peptide and Protein Research. 32: 536-43. PMID 3246478 DOI: 10.1111/J.1399-3011.1988.Tb01385.X |
0.33 |
|
1988 |
Karle IL, Flippen-Anderson JL, Sukumar M, Balaram P. Monoclinic polymorph of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe(anhydrous). Parallel packing of 3(10)-/alpha-helices and a transition of helix type. International Journal of Peptide and Protein Research. 31: 567-76. PMID 3079530 |
0.325 |
|
1988 |
Karle IL, Flippen-Anderson J, Uma K, Balaram P. Aqueous channels within apolar peptide aggregates: solvated helix of the alpha-aminoisobutyric acid (Aib)-containing peptide Boc-(Aib-Ala-Leu)3-Aib-OMe.2H2O.CH3OH in crystals. Proceedings of the National Academy of Sciences of the United States of America. 85: 299-303. PMID 2448772 DOI: 10.1073/Pnas.85.2.299 |
0.35 |
|
Low-probability matches (unlikely to be authored by this person) |
1997 |
Crisma M, Monaco V, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Crystallographic structure of a helical lipopeptaibol antibiotic analogue Letters in Peptide Science. 4: 213-218. DOI: 10.1007/Bf02442878 |
0.298 |
|
1990 |
Karle IL, Flippen-Anderson JL, Uma K, Sukumar M, Balaram P. Modular design of synthetic protein mimics. Crystal structures, assembly, and hydration of two 15- and 16-residue apolar, Leucyl-rich helical peptides Journal of the American Chemical Society. 112: 9350-9356. |
0.297 |
|
1996 |
Deschamps JR, George C, Flippen-Anderson JL. Structural studies of opioid peptides: a review of recent progress in x-ray diffraction studies. Biopolymers. 40: 121-39. PMID 8541444 DOI: 10.1002/Bip.360400102 |
0.297 |
|
1994 |
Karle IL, Flippen-Anderson JL, Gurunath R, Balaram P. Facile transition between 3(10)- and alpha-helix: structures of 8-, 9-, and 10-residue peptides containing the -(Leu-Aib-Ala)2-Phe-Aib- fragment. Protein Science : a Publication of the Protein Society. 3: 1547-55. PMID 7833814 DOI: 10.1002/Pro.5560030920 |
0.296 |
|
1991 |
Karle IL, Flippen-Anderson JL, Sukumar M, Uma K, Balaram P. Modular design of synthetic protein mimics. Crystal structure of two seven-residue helical peptide segments linked by ε-aminocaproic acid Journal of the American Chemical Society. 113: 3952-3956. |
0.294 |
|
1984 |
FLIPPEN-ANDERSON JL, GILARDI R, KARLE IL, FREY MH, OPELLA SJ, GIERASCH LM, GOODMAN M, MADISON V, DELANEY NG. ChemInform Abstract: CRYSTAL STRUCTURES, MOLECULAR CONFORMATIONS, INFRARED SPECTRA, AND CARBON-13 NMR SPECTRA OF METHYLPROLINE PEPTIDES IN THE SOLID STATE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198405070 |
0.292 |
|
2000 |
Deschamps JR, Flippen-Anderson JL, George C. 2-[N-(tert-Butoxycarbonyl)tyrosyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid nitromethane solvate Acta Crystallographica Section E Structure Reports Online. 57: o87-o90. DOI: 10.1107/S1600536800020109 |
0.292 |
|
1987 |
Karle IL, Flippen-Anderson J, Sukumar M, Balaram P. Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon. Proceedings of the National Academy of Sciences of the United States of America. 84: 5087-91. PMID 3474641 DOI: 10.1073/Pnas.84.15.5087 |
0.291 |
|
1991 |
Deschamps JR, George C, Flippen-Anderson JL, Musallam HA. Imidazolium chloride organophosphate antidotes Journal of Chemical Crystallography. 27: 541-548. DOI: 10.1007/Bf02576445 |
0.287 |
|
1996 |
Flippen-Anderson JL, George C, Valle G, Valente E, Bianco A, Formaggio F, Crisma M, Toniolo C. Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides. International Journal of Peptide and Protein Research. 47: 231-8. PMID 8738647 DOI: 10.1111/J.1399-3011.1996.Tb01350.X |
0.286 |
|
2002 |
Deschamps JR, Flippen-Anderson JL, George C. X-ray studies on ligands. Biopolymers. 66: 287-93. PMID 12539257 DOI: 10.1002/Bip.10308 |
0.285 |
|
1999 |
Doi M, Ishida T, Kobayashi M, Deschamps JR, Flippen-Anderson JL. The highly solvated structure of theonellapeptolide Id, a tridecapeptide lactone from the Okinawa marine spongeTheonella swinhoei Acta Crystallographica Section C Crystal Structure Communications. 55: 796-798. DOI: 10.1107/S0108270198014383 |
0.283 |
|
1999 |
Monaco V, Formaggio F, Crisma M, Toniolo C, Hanson P, Millhauser G, George C, Deschamps JR, Flippen-Anderson JL. Determining the occurrence of a 310-helix and an α-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C(α)-tetrasubstituted α-aminoacid Bioorganic and Medicinal Chemistry. 7: 119-131. PMID 10199662 DOI: 10.1016/S0968-0896(98)00220-X |
0.283 |
|
1989 |
Karle IL, Flippen-Anderson JL, Uma K, Balaram H, Balaram P. Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe. Proceedings of the National Academy of Sciences of the United States of America. 86: 765-9. PMID 2915976 DOI: 10.1073/Pnas.86.3.765 |
0.281 |
|
1978 |
Karle IL, Flippen-Anderson JL. Conformation of the cyclic tetrapeptide cyclo(-L-leucyl-L-tyrosyl-δ-amino valeryl-δ-aminovaleryl-) crystallized from acetone/H2O and comparison with the crystal from acetone/DMSO Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34: 3237-3241. DOI: 10.1107/S0567740878010572 |
0.281 |
|
1997 |
Flippen-Anderson JL, Deschamps JR, George C, Reddy PA, Lewin AH, Brine GA, Sheldrick G, Nikiforovich G. X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 384-93. PMID 9211219 DOI: 10.1111/J.1399-3011.1997.Tb00890.X |
0.279 |
|
1984 |
Flippen-Anderson JL, D'Antonio P, Konnert JH. Crystal structure of (E)-5-hydroxypyrrolizidin-3-one and (Z)-5-thioketalpyrrolizidin-3-one Journal of Crystallographic and Spectroscopic Research. 14: 565-572. DOI: 10.1007/BF01182143 |
0.276 |
|
2004 |
Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/Jo040159K |
0.274 |
|
1996 |
Deschamps JR, George C, Flippen-Anderson JL. [D-Ala2,D-Leu5]-enkephalin hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 1583-5. PMID 8766899 DOI: 10.1107/S0108270196000534 |
0.273 |
|
1996 |
Deschamps JR, George C, Flippen-Anderson JL. A diacetylmorphine polymorph. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 698-700. PMID 9004734 DOI: 10.1107/S0108270195013503 |
0.272 |
|
1990 |
Marchand AP, Annapurna P, Taylor RW, Simmons DL, Watson WH, Nagl A, Flippen-Anderson JL, Gilardi R, George C. Unusual behavior of 34:10,11-bis(2',3'-quinolino)tricyclo-[6.3.0.02,6] undecane upon attempted monoprotonation with triflic acid Tetrahedron. 46: 5077-5084. DOI: 10.1016/S0040-4020(01)87814-5 |
0.262 |
|
2005 |
Cao H, Van Ornum SG, Deschamps J, Flippen-Anderson J, Laib F, Cook JM. Synthesis of dicyclopenta[a,e]pentalenes via a molybdenum carbonyl mediated tandem allenic Pauson-Khand reaction and the X-ray crystal structure of a planar dicyclopenta[a,e]pentalene. Journal of the American Chemical Society. 127: 933-43. PMID 15656632 DOI: 10.1021/Ja040120X |
0.24 |
|
1989 |
Flippen-Anderson JL, George C, Gilardi R, Yu QS, Dominguez L, Brossi A. Structure of an ether dimer of deoxydihydroqinghaosu, a potential metabolite of the antimalarial arteether. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 292-4. PMID 2610970 |
0.236 |
|
1998 |
Thomas JB, Zheng X, Mascarella SW, Rothman RB, Dersch CM, Partilla JS, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-Substituted 9beta-methyl-5-(3-hydroxyphenyl)morphans are opioid receptor pure antagonists. Journal of Medicinal Chemistry. 41: 4143-9. PMID 9767649 DOI: 10.1021/jm980290i |
0.235 |
|
1999 |
Toniolo C, Formaggio F, Crisma M, Mazaleyrat J, Wakselman M, George C, Deschamps JR, Flippen-Anderson JL, Pispisa B, Venanzi M, Palleschi A. First Peptide-Based System of Rigid Donor-Rigid Interchromophore Spacer-Rigid Acceptor: A Structural and Photophysical Study Chemistry - a European Journal. 5: 2254-2264. DOI: 10.1002/(Sici)1521-3765(19990802)5:8<2254::Aid-Chem2254>3.0.Co;2-1 |
0.23 |
|
2003 |
Linders J, Mirsadeghi S, Flippen-Anderson J, George C, Jacobson A, Rice K. Probes for Narcotic Receptor Mediated Phenomena Helvetica Chimica Acta. 86: 484-493. DOI: 10.1002/Hlca.200390048 |
0.227 |
|
2001 |
Thomas JB, Herault XM, Rothman RB, Atkinson RN, Burgess JP, Mascarella SW, Dersch CM, Xu H, Flippen-Anderson JL, George CF, Carroll FI. Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides. Journal of Medicinal Chemistry. 44: 972-87. PMID 11300879 DOI: 10.1021/jm000427g |
0.227 |
|
1990 |
FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, REDDY GM. ChemInform Abstract: Structure of Diethyl 3,6-Dihydroxy-11,11-dimethoxypentacyclo(6.5.0.04,12.05,10.09,13)tridecane-2,6-diene-2,7-dicarboxylate. Cheminform. 21. DOI: 10.1002/CHIN.199005054 |
0.226 |
|
1990 |
Jarvis BB, Mazzocchi DB, Ammon HL, Mazzola EP, Flippen-Anderson JL, Gilardi RD, George CF. Conformational effects in trichothecenes: structures of 15-hydroxy C4 and C8 ketones The Journal of Organic Chemistry. 55: 3660-3662. DOI: 10.1021/JO00298A053 |
0.224 |
|
1986 |
Schönenberger B, Jacobson AE, Brossi A, Streaty R, Klee WA, Flippen-Anderson JL, Gilardi R. Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogues in antinociceptive assays: confirmation of rubreserine structure by X-ray analysis. Journal of Medicinal Chemistry. 29: 2268-73. PMID 3023611 |
0.224 |
|
2003 |
Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α -(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide and (-)-4-[(αR)-α -(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide Bioorganic and Medicinal Chemistry. 11: 4761-4768. PMID 14556791 DOI: 10.1016/S0968-0896(03)00496-6 |
0.224 |
|
1989 |
Flippen-Anderson JL, Gilardi R, George C, Marchand AP, Reddy GM. Structure of diethyl 3,6-dihydroxy-11,11-dimethoxypentacyclo[6.5.0.04,12.05,10.09,13]tridecane-2,6-diene-2,7-dicarboxylate Acta Crystallographica Section C Crystal Structure Communications. 45: 1548-1551. DOI: 10.1107/S0108270189001757 |
0.221 |
|
1987 |
Flippen-Anderson JL, Gilardi R, George C. Structure of 6-hydroxy-2,5-dinitro-2,5-diazacyclohexyl acetate Acta Crystallographica Section C Crystal Structure Communications. 43: 2022-2023. DOI: 10.1107/S0108270187089170 |
0.217 |
|
1984 |
Karle IL, Flippen-Anderson JL, Chiang JF, Lowrey AH. The conformations of five tetra- and pentamethoxylated phenyl derivatives: weberine analogs and polymethoprims Acta Crystallographica Section B Structural Science. 40: 500-506. DOI: 10.1107/S010876818400255X |
0.216 |
|
2001 |
Flippen-Anderson JL, Deschamps JR, George C, Folk JE, Jacobson AE, Rice KC. Twinned 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenyl)propyl)piperazinium chloride (GBR12909) Acta Crystallographica Section E Structure Reports Online. 58: o81-o82. DOI: 10.1107/S1600536801021389 |
0.215 |
|
1997 |
Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands. Journal of Medicinal Chemistry. 40: 695-704. PMID 9057856 DOI: 10.1021/Jm960319N |
0.214 |
|
1989 |
FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, REDDY GM. ChemInform Abstract: Structure of a 3-Methylpentacyclo(5.4.0.02,6.03,10.05,9)undecane-8,11-dione Monoethylene Ketal. Cheminform. 20. DOI: 10.1002/CHIN.198939134 |
0.214 |
|
1991 |
Oliver JE, Waters RM, Lusby WR, Flippen-Anderson JL. A macrocyclic amide from dehydrochlorination of indole-3-carbonyl chloride Journal of Heterocyclic Chemistry. 28: 1569-1572. DOI: 10.1002/JHET.5570280619 |
0.212 |
|
1991 |
Gilardi R, George C, Flippen-Anderson JL, Zajac WW, Walters TR, Woods JM. Structure of 1-amino-3,5,7-trinitroadamantane Acta Crystallographica Section C: Crystal Structure Communications. 47: 1914-1916. DOI: 10.1107/S0108270191001853 |
0.211 |
|
2010 |
Doi M, Ishida T, Kobayashi M, Deschamps JR, Flippen-Anderson JL. ChemInform Abstract: The Highly Solvated Structure of Theonellapeptolide Id, a Tridecapeptide Lactone from the Okinawa Marine Sponge Theonella swinhoei. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199932213 |
0.21 |
|
1986 |
GLEASON FK, PORWOLL J, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: X-Ray Structure Determination of the Naturally Occurring Isomer of Cyanobacterin. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198650066 |
0.208 |
|
1999 |
Yu H, Wang L, Flippen-Anderson JL, Tian X, Coop A, Rice KC. Synthesis of a novel 7,14β-ethano-bridged opiate Heterocycles. 51: 2343-2347. DOI: 10.3987/Com-99-8591 |
0.208 |
|
1993 |
Flippen-Anderson JL, Zajac WW, Buzby JH, Walters TR. Structure of 1-benzoyl-4,4,5,5-tetramethyl-2-phenylimidazoline hydrate Acta Crystallographica Section C Crystal Structure Communications. 49: 1792-1793. DOI: 10.1107/S0108270193002276 |
0.207 |
|
1994 |
Bertha CM, Mattson MV, Flippen-Anderson JL, Rothman RB, Xu H, Cha XY, Becketts K, Rice KC. A marked change of receptor affinity of the 2-methyl-5-(3-hydroxyphenyl)morphans upon attachment of an (E)-8-benzylidene moiety: synthesis and evaluation of a new class of sigma receptor ligands. Journal of Medicinal Chemistry. 37: 3163-70. PMID 7932540 DOI: 10.1021/Jm00045A022 |
0.206 |
|
1996 |
Flippen-Anderson JL, Deschamps J, George C, Hruby VJ, Li G, Lipkowski AW, Misicka A. Biphalin, a highly potent dimeric enkephalin analog Acta Crystallographica Section a Foundations of Crystallography. 52: C253-C253. DOI: 10.1107/S0108767396089325 |
0.203 |
|
1991 |
Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Archiv Der Pharmazie. 324: 29-33. PMID 2043039 DOI: 10.1002/Ardp.19913240109 |
0.201 |
|
1986 |
Gleason FK, Porwoll J, Flippen-Anderson JL, George C. X-ray structure determination of the naturally occurring isomer of cyanobacterin The Journal of Organic Chemistry. 51: 1615-1616. DOI: 10.1021/Jo00359A050 |
0.2 |
|
2002 |
Deschamps JR, George C, Flippen-Anderson JL. (1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o362-4. PMID 12050443 DOI: 10.1107/S0108270102006443 |
0.197 |
|
2005 |
Runyon SP, Burgess JP, Abraham P, Keverline-Frantz KI, Flippen-Anderson J, Deschamps J, Lewin AH, Navarro HA, Boja JW, Kuhar MJ, Carroll FI. Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product. Bioorganic & Medicinal Chemistry. 13: 2439-49. PMID 15755646 DOI: 10.1016/J.Bmc.2005.01.046 |
0.197 |
|
2002 |
Hashimoto A, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan. Bioorganic & Medicinal Chemistry. 10: 3319-29. PMID 12150879 DOI: 10.1016/S0968-0896(02)00219-5 |
0.196 |
|
2000 |
Hoepping A, Johnson KM, George C, Flippen-Anderson J, Kozikowski AP. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter. Journal of Medicinal Chemistry. 43: 2064-71. PMID 10821718 DOI: 10.1021/Jm0001121 |
0.194 |
|
2010 |
OLIVER JE, WATERS RM, LUSBY WR, FLIPPEN-ANDERSON JL. ChemInform Abstract: A Macrocyclic Amide from Dehydrochlorination of Indole-3-carbonyl Chloride. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199213237 |
0.192 |
|
1989 |
FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, DAVE PR. ChemInform Abstract: Structure of a Cage Dimer and a Dimer Ketone Formed via Thermal Reaction of Ethyl 3-Phenyl-2-norbornadienecarboxylate with Pentacarbonyliron Cheminform. 20. DOI: 10.1002/CHIN.198947048 |
0.191 |
|
1991 |
Gilardi R, Flippen-Anderson JL, George C. Structure of 2,2-dinitro-1,3-propanediyl bis[(N-pentafluorosulfanyl)carbamate] (I) and 2-fluoro-2,2-dinitroethyl (N-pentafluorosulfanyl)carbamate (II) Acta Crystallographica Section C Crystal Structure Communications. 47: 442-445. DOI: 10.1107/S0108270190006977 |
0.191 |
|
1992 |
Flippen-Anderson JL, George C. Absolute configuration of (-)-alpha-acetylmethadol hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 48: 1855-7. PMID 1445673 |
0.19 |
|
1992 |
Gilardi R, George C, Flippen-Anderson JL. Structure of 1,1,3,3-tetranitrocyclobutane Acta Crystallographica Section C Crystal Structure Communications. 48: 1680-1681. DOI: 10.1107/S0108270192000702 |
0.19 |
|
2003 |
Przybyl AK, Flippen-Anderson JL, Jacobson AE, Rice KC. Practical and high-yield syntheses of dihydromorphine from tetrahydrothebaine and efficient syntheses of (8S)-8-bromomorphide. The Journal of Organic Chemistry. 68: 2010-3. PMID 12608825 DOI: 10.1021/Jo0206871 |
0.187 |
|
1996 |
Bertha CM, Ellis M, Flippen-Anderson JL, Porreca F, Rothman RB, Davis P, Xu H, Becketts K, Rice KC. Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity. Journal of Medicinal Chemistry. 39: 2081-6. PMID 8642567 DOI: 10.1021/Jm950695S |
0.186 |
|
2004 |
Kodato S, Linders JT, Gu XH, Yamada K, Flippen-Anderson JL, Deschamps JR, Jacobson AE, Rice KC. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers. Organic & Biomolecular Chemistry. 2: 330-6. PMID 14747861 DOI: 10.1039/B312633C |
0.186 |
|
2001 |
Yu Q, Holloway HW, Flippen-Anderson JL, Hoffman B, Brossi A, Greig NH. Methyl analogues of the experimental Alzheimer drug phenserine: synthesis and structure/activity relationships for acetyl- and butyrylcholinesterase inhibitory action. Journal of Medicinal Chemistry. 44: 4062-71. PMID 11708910 DOI: 10.1021/Jm010080X |
0.186 |
|
1992 |
Agarwalla S, Mellor IR, Sansom MS, Karle IL, Flippen-Anderson JL, Uma K, Krishna K, Sukumar M, Balaram P. Zervamicins, a structurally characterised peptide model for membrane ion channels. Biochemical and Biophysical Research Communications. 186: 8-15. PMID 1378732 DOI: 10.1016/S0006-291X(05)80768-5 |
0.185 |
|
1995 |
Bertha CM, Vilner BJ, Mattson MV, Bowen WD, Becketts K, Xu H, Rothman RB, Flippen-Anderson JL, Rice KC. (E)-8-benzylidene derivatives of 2-methyl-5-(3-hydroxyphenyl)morphans: highly selective ligands for the sigma 2 receptor subtype. Journal of Medicinal Chemistry. 38: 4776-85. PMID 7490727 DOI: 10.1021/Jm00024A005 |
0.184 |
|
1983 |
BROSSI A, ATWELL L, JACOBSON AE, ROZWADOWSKA MD, SCHMIDHAMMER H, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: STRUCTURE-ACTIVITY RELATIONSHIP OF OXYGENATED MORPHINANS. VII. 5-METHYLATED AND 14-HYDROXY-SUBSTITUTED AGONISTS AND ANTAGONISTS OF THE 4-HYDROXY- AND 3,4-DIOXYGENATED 6-MORPHINANONE SERIES Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198315343 |
0.183 |
|
1998 |
Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, George C, Saiah E. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton. Journal of Medicinal Chemistry. 41: 1962-9. PMID 9599245 DOI: 10.1021/Jm980028+ |
0.18 |
|
1993 |
Flippen-Anderson JL, George C, Deschamps J. Hydrogen-bonding patterns in X-ray diffraction studies of neuropeptides Acta Crystallographica Section a Foundations of Crystallography. 49: c144-c144. DOI: 10.1107/S0108767378095872 |
0.18 |
|
2005 |
Wang YN, Bohle DS, Bonifant CL, Chmurny GN, Collins JR, Davies KM, Deschamps J, Flippen-Anderson JL, Keefer LK, Klose JR, Saavedra JE, Waterhouse DJ, Ivanic J. Chemistry of the diazeniumdiolates: Z ⇌ E isomerism Journal of the American Chemical Society. 127: 5388-5395. PMID 15826177 DOI: 10.1021/Ja042258L |
0.179 |
|
1982 |
Brossi A, Atwell L, Jacobson AE, Rozwadowska MD, Schmidhammer H, Flippen-Anderson JL, Gilardi R. Structure-Activity Relationship of Oxygenated Morphinans. VII. 5-Methylated and 14-Hydroxy-substituted Agonists and Antagonists of the 4-Hydroxy- and 3, 4-Dioxygenated 6-Morphinanone Series Helvetica Chimica Acta. 65: 2394-2404. DOI: 10.1002/HLCA.19820650804 |
0.179 |
|
1981 |
Spencer GF, Flippen-Anderson JL. Isolation and X-ray structure determination of a neolignan from Clerodendron inerme seeds Phytochemistry. 20: 2757-2759. DOI: 10.1016/0031-9422(81)85281-8 |
0.177 |
|
1994 |
Flippen-Anderson JL, George C, Deschamps JR. Methyl N,N-diallyl-O-tert-butyltyrosyl-alpha-aminoisobutyrl-alpha- aminoisobutyrate, C28H43N3O5. Acta Crystallographica. Section C, Crystal Structure Communications. 50: 1095-7. PMID 8074811 DOI: 10.1107/S0108270193012387 |
0.176 |
|
2003 |
Chen W, Metcalf MD, Coop A, Flippen-Anderson JL, Deschamps JR. 5-Butylthevinone: Stereochemistry of the Diels-Alder reaction of 5-butylthebaine with 3-buten-2-one Acta Crystallographica Section E: Structure Reports Online. 59: o114-i116. DOI: 10.1107/S1600536802023413 |
0.176 |
|
1983 |
Fodor G, Arnold R, Mohacsi T, Karle I, Flippen-Anderson J. A new role for l-ascorbic acid: michael donor to α,β-unsaturated carbonyl compounds Tetrahedron. 39: 2137-2145. DOI: 10.1016/S0040-4020(01)91929-5 |
0.175 |
|
2003 |
Yu J, Wang T, Liu X, Deschamps J, Flippen-Anderson J, Liao X, Cook JM. General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine. The Journal of Organic Chemistry. 68: 7565-81. PMID 14510528 DOI: 10.1021/Jo030006H |
0.175 |
|
1997 |
Katsura Y, Zhang X, Homma K, Rice KC, Calderon SN, Rothman RB, Yamamura HI, Davis P, Flippen-Anderson JL, Xu H, Becketts K, Foltz EJ, Porreca F. Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. Journal of Medicinal Chemistry. 40: 2936-47. PMID 9288176 DOI: 10.1021/Jm970106D |
0.175 |
|
1987 |
Flippen-Anderson JL, Gilardi R, George C. Structure of bruceine B hydrate Acta Crystallographica Section C Crystal Structure Communications. 43: 801-803. DOI: 10.1107/S0108270187094022 |
0.174 |
|
1992 |
Flippen-Anderson JL, George C, Gilardi R. Structure of 2,4,6-trinitro-8,10-dipropionyl-2,4,6,8,10-pentaazabicyclo[5.3.0]decane Acta Crystallographica Section C Crystal Structure Communications. 48: 1530-1531. DOI: 10.1107/S0108270191015123 |
0.174 |
|
2001 |
Zhang Y, Joseph DB, Bowen WD, Flippen-Anderson JL, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues. Journal of Medicinal Chemistry. 44: 3937-45. PMID 11689080 DOI: 10.1021/Jm0101592 |
0.174 |
|
1992 |
Gilardi R, George C, Flippen-Anderson JL. Structure of 3-nitrato-1-nitroazetidine Acta Crystallographica Section C Crystal Structure Communications. 48: 1679-1680. DOI: 10.1107/S0108270192000696 |
0.173 |
|
2010 |
PEI X, GREIG NH, FLIPPEN-ANDERSON JL, BI S, BROSSI A. ChemInform Abstract: Total Synthesis of Racemic and Optically Active Compounds Related to Physostigmine and Ring-C Heteroanalogues from 3-(2′-(Dimethylamino) ethyl)-2,3-dihydro-5-methoxy-1,3-dimethyl-1H-indol-2-ol. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199452244 |
0.172 |
|
1994 |
Pei X, Greig NH, Flippen-Anderson JL, Bi S, Brossi A. Total Synthesis of Racemic and Optically Active Compounds Related to Physostigmine and Ring-C Heteroanalogues from 3-[2?-(dimethylamino)ethyl]2,3-dihydro-5-methoxy-1,3-dimethyl-1H-indo l-2-ol Helvetica Chimica Acta. 77: 1412-1422. DOI: 10.1002/HLCA.19940770519 |
0.169 |
|
2001 |
Keefer LK, Flippen-Anderson JL, George C, Shanklin AP, Dunams TM, Christodoulou D, Saavedra JE, Sagan ES, Bohle DS. Chemistry of the diazeniumdiolates. I. Structural and spectral characteristics of the [N(O)NO]- functional group. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 377-94. PMID 11485376 DOI: 10.1006/Niox.2001.0359 |
0.168 |
|
2001 |
Ma C, Liu X, Li X, Flippen-Anderson J, Yu S, Cook JM. Efficient asymmetric synthesis of biologically important tryptophan analogues via a palladium-mediated heteroannulation reaction. The Journal of Organic Chemistry. 66: 4525-42. PMID 11421771 DOI: 10.1021/Jo001679S |
0.167 |
|
1995 |
Bertha CM, Flippen-Anderson JL, Rothman RB, Porreca F, Davis P, Xu H, Becketts K, Cha XY, Rice KC. Probes for narcotic receptor-mediated phenomena. 20. Alteration of opioid receptor subtype selectivity of the 5-(3-hydroxyphenyl)morphans by application of the message-address concept: preparation of delta-opioid receptor ligands. Journal of Medicinal Chemistry. 38: 1523-37. PMID 7739011 DOI: 10.1021/Jm00009A013 |
0.165 |
|
1989 |
George C, Flippen-Anderson JL, Gilardi R. Structure of the simple trichothecene 7α-hydroxyscirpene Acta Crystallographica Section C Crystal Structure Communications. 45: 1663-1665. DOI: 10.1107/S0108270189006979 |
0.164 |
|
1995 |
Lei PS, Ogawa Y, Flippen-Anderson JL, Kovác P. Synthesis and crystal structure of methyl 4-6-dideoxy-4-(3-deoxy-L- glycero-tetronamido)-2-O-methyl-alpha-D-mannopyranoside, the methyl alpha-glycoside of the terminal unit, and presumed antigenic determinant, of the O-specific polysaccharide of Vibrio cholerae O:1, serotype Ogawa. Carbohydrate Research. 275: 117-29. PMID 7585718 |
0.163 |
|
1982 |
Jarvis BB, Midiwo JO, Flippen-Anderson JL, Mazzola EP. Stereochemistry of the Roridins Journal of Natural Products. 45: 440-448. DOI: 10.1021/NP50022A014 |
0.162 |
|
1989 |
Yu QS, Yeh HJ, Brossi A, Flippen-Anderson JL. Geneserine and geneseroline revisited: acid-base catalyzed equilibria of hexahydropyrrolo-[2,3-b]-indole N-oxides with hexahydro-1,2-oxazino-[5,6-b]-indoles. Journal of Natural Products. 52: 332-6. PMID 2746259 |
0.161 |
|
2010 |
CALDERON SN, ROTHMAN RB, PORRECA F, FLIPPEN-ANDERSON JL, MCNUTT RW, XU H, SMITH LE, BILSKY EJ, DAVIS P, RICE KC. ChemInform Abstract: Probes for Narcotic Receptor Mediated Phenomena. Part 19. Synthesis of (+)-4-((αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)- 3-methoxybenzyl)-N,N-diethylbenzamide (SNC 80): A Highly Selective, Nonpeptide δ Opioid Receptor Agonis Cheminform. 25: no-no. DOI: 10.1002/CHIN.199448177 |
0.16 |
|
1998 |
Kozikowski AP, Araldi GL, Flippen-Anderson J, George C, Pshenichkin S, Surina E, Wroblewski J. Synthesis and metabotropic glutamate receptor activity of a 2- aminobicyclo[3.2.0]Heptane-2,5-dicarboxylic acid, a molecule possessing an extended glutamate conformation Bioorganic and Medicinal Chemistry Letters. 8: 925-930. PMID 9871513 DOI: 10.1016/S0960-894X(98)00146-2 |
0.16 |
|
2003 |
Zhao S, Liao X, Wang T, Flippen-Anderson J, Cook JM. The enantiospecific, stereospecific total synthesis of the ring-A oxygenated sarpagine indole alkaloids (+)-majvinine, (+)-10-methoxyaffinisine, and (+)-N(a)-methylsarpagine, as well as the total synthesis of the alstonia bisindole alkaloid macralstonidine. The Journal of Organic Chemistry. 68: 6279-95. PMID 12895062 DOI: 10.1021/Jo030055U |
0.158 |
|
2001 |
Zhang J, Flippen-Anderson JL, Kozikowski AP. A tandem Michael addition ring-closure route to the metabotropic receptor ligand α-(hydroxymethyl)glutamic acid and its γ-alkylated derivatives Journal of Organic Chemistry. 66: 7555-7559. PMID 11681981 DOI: 10.1021/jo010626n |
0.156 |
|
1990 |
Lin AJ, Li LQ, Klayman DL, George CF, Flippen-Anderson JL. Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 3. Aromatic amine analogues. Journal of Medicinal Chemistry. 33: 2610-4. PMID 2202831 DOI: 10.1021/jm00171a041 |
0.153 |
|
2010 |
BERTHA CM, ELLIS M, FLIPPEN-ANDERSON JL, PORRECA F, ROTHMAN RB, DAVIS P, XU H, BECKETTS K, RICE KC. ChemInform Abstract: Probes for Narcotic Receptor-Mediated Phenomena. Part 21. Novel Derivatives of 3-(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-6H- azocino(4,5-b)indol-6-yl)phenols with Improved δ Opioid Receptor Selectivity. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199635165 |
0.151 |
|
1987 |
Yu QS, Brossi A, Flippen-Anderson JL. S-configuration of (+)-primaquine by X-ray analysis of the urea obtained with R-(+)-1-phenylethylisocyanate. Febs Letters. 221: 325-6. PMID 3622772 DOI: 10.1016/0014-5793(87)80949-3 |
0.149 |
|
2002 |
Appell M, Dunn WJ, Reith ME, Miller L, Flippen-Anderson JL. An analysis of the binding of cocaine analogues to the monoamine transporters using tensor decomposition 3-d QSAR. Bioorganic & Medicinal Chemistry. 10: 1197-206. PMID 11886784 |
0.147 |
|
1988 |
MARCHAND AP, ANNAPURNA GS, VIDYASAGAR V, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, AMMON HL. ChemInform Abstract: Synthesis of Nitro-Substituted 2,3,4,8-Tetraphenylpentacyclo-(5.3.0.02,5.03,9.04,8)decanes. Cheminform. 19. DOI: 10.1002/CHIN.198813121 |
0.146 |
|
1982 |
BUCHS P, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: (E)-5-HYDROXYPYRROLIZIDIN-3-ONE: VERSATILE SYNTHON FOR THE SYNTHESIS OF 5-SUBSTITUTED 2-PYRROLIDONES AND (Z)-3-ALKYLPYRROLIZIDINES Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198235198 |
0.146 |
|
2001 |
Saavedra JE, Srinivasan A, Bonifant CL, Chu J, Shanklin AP, Flippen-Anderson JL, Rice WG, Turpin JA, Davies KM, Keefer LK. The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions. The Journal of Organic Chemistry. 66: 3090-8. PMID 11325274 DOI: 10.1021/Jo0016529 |
0.145 |
|
2001 |
Flippen-Anderson JL, Axenrod T, Qi L, Gilardi RD. 1,5-Di-tert-butyl-3-hydroxy-7-methylene-1-azonia-5-azacyclooctane iodide Acta Crystallographica Section E Structure Reports Online. 57: o1147-o1148. DOI: 10.1107/S1600536801018190 |
0.145 |
|
2010 |
KOZIKOWSKI AP, ARALDI GL, FLIPPEN-ANDERSON J, GEORGE C, PSHENICHKIN S, SURINA E, WROBLEWSKI J. ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Activity of a 2-Aminobicyclo[3.2.0]heptane-2,5-dicarboxylic Acid, a Molecule Possessing an Extended Glutamate Conformation. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199834228 |
0.145 |
|
1989 |
Itoh Y, Brossi A, Hamel E, Flippen-Anderson JL, George C. Colchicine models: Synthesis and Antitubulin Activity of 2?-Monosubstituted and 2?, 5-Disubstituted 2,3,4,4?-Tetramethoxy-1,1?-biphenyls. Synthesis of 4,4?, 5?, 6?-tetramethoxy-1,1?-biphenyl-2,3?-dicarboxylic acid Helvetica Chimica Acta. 72: 196-204. DOI: 10.1002/Hlca.19890720203 |
0.143 |
|
2003 |
Chen W, Wu H, Bernard D, Metcalf MD, Deschamps JR, Flippen-Anderson JL, MacKerell AD, Coop A. Rearrangement of 5-trimethylsilylthebaine on treatment with L-selectride: an efficient synthesis of (+)-bractazonine. The Journal of Organic Chemistry. 68: 1929-32. PMID 12608812 DOI: 10.1021/Jo020704M |
0.142 |
|
1988 |
KEEFER LK, HRABIE JA, OHANNESIAN L, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: A Symmetrically Hydrogen-Bonded “Binitrosamine Cation” Produced on Protonation of N-Nitrosopyrrolidine Cheminform. 19. DOI: 10.1002/CHIN.198838063 |
0.142 |
|
1988 |
Keefer LK, Hrabie JA, Ohannesian L, Flippen-Anderson JL, George C. A symmetrically hydrogen-bonded binitrosamine cation produced on protonation of N-nitrosopyrrolidine Journal of the American Chemical Society. 110: 3701-3702. DOI: 10.1021/Ja00219A078 |
0.141 |
|
1987 |
Karle IL, Flippen-Anderson J, Sukumar M, Balaram P. Parallel packing of alpha-helices in crystals of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-Ala-Aib-Pro-Aib-Pro-Phe-OMe·4H2O·2CH3OH Acta Crystallographica Section a Foundations of Crystallography. 43: C51-C51. DOI: 10.1107/S0108767387084149 |
0.141 |
|
1999 |
Linders JT, Flippen-Anderson JL, George CF, Rice KC. An expedient synthesis of 9-keto-2-methyl-5-(dimethoxyphenyl)morphans Tetrahedron Letters. 40: 3905-3908. DOI: 10.1016/S0040-4039(99)00566-3 |
0.139 |
|
1987 |
Marchand AP, Annapurna GS, Vidyasagar V, Flippen-Anderson JL, Gilardi R, George C, Ammon HL. Synthesis of nitro-substituted 2,3,4,8-tetraphenylpentacyclo[5.3.0.02,5.03,9.04,8]decanes The Journal of Organic Chemistry. 52: 4781-4783. DOI: 10.1021/JO00230A024 |
0.139 |
|
1998 |
Thomas JB, Mascarella SW, Burgess JP, Xu H, McCullough KB, Rothman RB, Flippen-Anderson JL, George CF, Cantrell BE, Zimmerman DM, Carroll FI. N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 3149-52. PMID 9873693 |
0.138 |
|
1982 |
Buchs P, Brossi A, Flippen-Anderson JL. (E)-5-Hydroxypyrrolizidin-3-one: versatile synthon for the synthesis of 5-substituted 2-pyrrolidones and (Z)-3-alkylpyrrolizidines The Journal of Organic Chemistry. 47: 719-723. DOI: 10.1021/JO00343A023 |
0.136 |
|
1989 |
ITOH Y, BROSSI A, HAMEL E, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Colchicine Models: Synthesis and Antitubulin Activity of 2′-Monosubstituted and 2′,5-Disubstituted 2,3,4,4′-Tetramethoxy-1,1′-biphenyls. Synthesis of 4,4′,5′,6′-Tetramethoxy-1,1′-biphenyl-2,3′-dicarboxylic Acid. Cheminform. 20. DOI: 10.1002/CHIN.198924293 |
0.136 |
|
2000 |
Axenrod T, Sun J, Das KK, Dave PR, Forohar F, Kaselj M, Trivedi NJ, Gilardi RD, Flippen-Anderson JL. Synthesis and characterization of 5-substituted 1,3-diazacyclohexane derivatives The Journal of Organic Chemistry. 65: 1200-6. PMID 10814072 DOI: 10.1021/jo991524o |
0.135 |
|
2000 |
Tamiz AP, Zhang J, Flippen-Anderson JL, Zhang M, Johnson KM, Deschaux O, Tella S, Kozikowski AP. Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors. Journal of Medicinal Chemistry. 43: 1215-22. PMID 10737754 DOI: 10.1021/jm9905561 |
0.135 |
|
1988 |
Guy JT, Cooper JC, Gilardi RD, Flippen-Anderson JL, George CF. Transition-metal-promoted oxidation of organic sulfides. Synthesis, characterization, and structure of (.mu.4-oxo)hexakis(.mu.2-chloro)tetrakis(dialkyl sulfoxide)tetracopper(II) Inorganic Chemistry. 27: 635-638. DOI: 10.1021/IC00277A013 |
0.134 |
|
2002 |
Deschamps JR, Flippen-Anderson JL, George C. Sodium 2-(N-morpholino)ethanesulfonate monohydrate Acta Crystallographica Section E Structure Reports Online. 58: m167-m168. DOI: 10.1107/S160053680200541X |
0.134 |
|
1984 |
Flippen-Anderson JL, Gilardi R. Laser dye intermediates: structures of 1,2,3,4-tetrahydroquinolinium-7-sulfonate monohydrate (I), C9H11NO3S.H2O, and twinned 1,2,3,4-tetrahydro-1-methylquinolinium-7-sulfonate (II), C10H13NO3S Acta Crystallographica Section C Crystal Structure Communications. 40: 1065-1068. DOI: 10.1107/S0108270184006806 |
0.133 |
|
1988 |
MARCHAND AP, JIN P, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE G. ChemInform Abstract: A Novel Rearrangement in a 1,3-Bishomocubyl Ring System. Cheminform. 19. DOI: 10.1002/CHIN.198802135 |
0.133 |
|
1994 |
Calderon SN, Rothman RB, Porreca F, Flippen-Anderson JL, McNutt RW, Xu H, Smith LE, Bilsky EJ, Davis P, Rice KC. Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(alpha R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3- methoxybenzyl]-N,N-diethylbenzamide (SNC 80): a highly selective, nonpeptide delta opioid receptor agonist. Journal of Medicinal Chemistry. 37: 2125-8. PMID 8035418 DOI: 10.1021/Jm00040A002 |
0.133 |
|
1984 |
Flippen-Anderson JL, Gilardi R. Structures of three photodimers of 5-fluoro-1,3-dimethyluracil: (I) an anti cyclobutene dimer, C12H13FN4O4; (II) the trans–anti cyclobutane dimer, C12H14F2N4O4; and (III) the cis–syn cyclobutane dimer, C12H14F2N4O4 Acta Crystallographica Section C Crystal Structure Communications. 40: 1957-1960. DOI: 10.1107/S0108270184010210 |
0.132 |
|
2010 |
Carroll FI, Zhang X, Abraham P, Mascarella SW, Flippen-Anderson J, Deschamps JR. Enantioselective synthesis of strobamine and its analogues Arkivoc. 2010: 96-103. DOI: 10.3998/ark.5550190.0011.409 |
0.13 |
|
2000 |
Hoepping A, George C, Flippen-Anderson J, Kozikowski AP. Radical cyclization strategies for the formation of ring constrained tricyclic tropane analogues Tetrahedron Letters. 41: 7427-7432. DOI: 10.1016/S0040-4039(00)01288-0 |
0.13 |
|
2010 |
Ma C, Liu X, Li X, Flippen-Anderson J, Yu S, Cook JM. ChemInform Abstract: Efficient Asymmetric Synthesis of Biologically Important Tryptophan Analogues via a Palladium-Mediated Heteroannulation Reaction. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200146187 |
0.129 |
|
1987 |
FODOR G, SUSSANGKARN K, MATHELIER H, FANG K, ARNOLD R, FLIPPEN-ANDERSON J, KARLE I. ChemInform Abstract: Stereospecificity of a New Reaction of L-Ascorbic Acid with cis and trans Olefinic 1,4-Dicarbonyl Compounds. Cheminform. 18. DOI: 10.1002/CHIN.198705192 |
0.126 |
|
1988 |
GUY JTJ, COOPER JC, GILARDI RD, FLIPPEN-ANDERSON JL, GEORGE CFJ. ChemInform Abstract: Transition-Metal-Promoted Oxidation of Organic Sulfides. Synthesis, Characterization, and Structure of (μ4-Oxo)hexakis(μ2-chloro)tetrakis(dialkyl sulfoxide)tetracopper(II). Cheminform. 19. DOI: 10.1002/CHIN.198825304 |
0.126 |
|
1988 |
MARCHAND AP, ARNEY BEJ, GILARDI R, FLIPPEN-ANDERSON JL. ChemInform Abstract: Lewis Acid Promoter Reaction of Pentacyclo(5.4.0.02,6.03,10.05,9)undecane-8,11-dione with Ethyl Diazoacetate: A Synthetic Entry into the Pentacyclo(6.5.0.04,12.05,10.09,13)tridecane Ring System. Cheminform. 19. DOI: 10.1002/CHIN.198802133 |
0.124 |
|
2010 |
NIELSEN AT, CHAFIN AP, CHRISTIAN SL, MOORE DW, NADLER MP, NISSAN RA, VANDERAH DJ, GILARDI RD, GEORGE CF, FLIPPEN-ANDERSON JL. ChemInform Abstract: Synthesis of Polyazapolycyclic Caged Polynitramines. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199852187 |
0.124 |
|
1986 |
HANSEN JF, FLIPPEN-ANDERSON JL. ChemInform Abstract: Stereochemical Assignments for 1-Phenyl-1,2,3-butanetrione 2-Oxime and Related Compounds. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198612112 |
0.124 |
|
2000 |
Tamiz AP, Smith MP, Enyedy I, Flippen-Anderson J, Zhang M, Johnson KM, Kozikowski AP. Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry Letters. 10: 1681-6. PMID 10937724 DOI: 10.1016/S0960-894X(00)00308-5 |
0.123 |
|
1990 |
GILARDI R, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: The Structure of T-2 Toxin Cheminform. 21. DOI: 10.1002/CHIN.199031315 |
0.123 |
|
1997 |
Crisma M, Monaco V, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Letters in Peptide Science. 4: 213-218. DOI: 10.1023/A:1008874816982 |
0.12 |
|
2004 |
Ding K, Flippen-Anderson J, Deschamps JR, Wang S. An efficient synthesis of optically pure (S)-2-functionalized 1,2,3,4-tetrahydroquinoline Tetrahedron Letters. 45: 1027-1029. DOI: 10.1016/J.Tetlet.2003.11.086 |
0.12 |
|
1988 |
Brossi A, Venugopalan B, Dominguez Gerpe L, Yeh HJ, Flippen-Anderson JL, Buchs P, Luo XD, Milhous W, Peters W. Arteether, a new antimalarial drug: synthesis and antimalarial properties. Journal of Medicinal Chemistry. 31: 645-50. PMID 3279208 |
0.117 |
|
1987 |
Gilardi R, Flippen-Anderson JL. The tetrasaccharide stachyose Acta Crystallographica Section C Crystal Structure Communications. 43: 806-808. DOI: 10.1107/S0108270187093995 |
0.115 |
|
1996 |
Crisma M, Bianco A, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Tryptophan-containing polypeptide 3(10)-helices. Side-chain interactions and molecular recognition studies. Advances in Experimental Medicine and Biology. 398: 623-6. PMID 8906336 |
0.115 |
|
1989 |
MARCHAND AP, DAVE PR, RAJAPAKSA D, ARNEY BEJ, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C. ChemInform Abstract: Synthesis of 4,4,8,8,11,11-Hexanitropentacyclo(5.4.0.02,6.03,10.05,9)-undecane. Cheminform. 20. DOI: 10.1002/CHIN.198943099 |
0.114 |
|
2010 |
FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Absolute Configuration of (-)-α-Acetylmethadol Hydrochloride. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199305051 |
0.113 |
|
2002 |
Prakash KR, Tang Y, Kozikowski AP, Flippen-Anderson JL, Knoblach SM, Faden AI. Synthesis and biological activity of novel neuroprotective diketopiperazines. Bioorganic & Medicinal Chemistry. 10: 3043-8. PMID 12110327 DOI: 10.1016/S0968-0896(02)00132-3 |
0.113 |
|
1990 |
FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, MARCHAND AP, DAVE PR. ChemInform Abstract: Structure of a Dimer Ketone Formed via Fe(CO)5-Promoted Coupling of 7-(p-Cyanophenoxy)norbornadiene to Carbon Monoxide. Cheminform. 21. DOI: 10.1002/CHIN.199035050 |
0.112 |
|
2008 |
Henrick K, Feng Z, Bluhm WF, Dimitropoulos D, Doreleijers JF, Dutta S, Flippen-Anderson JL, Ionides J, Kamada C, Krissinel E, Lawson CL, Markley JL, Nakamura H, Newman R, Shimizu Y, et al. Remediation of the protein data bank archive. Nucleic Acids Research. 36: D426-33. PMID 18073189 DOI: 10.1093/Nar/Gkm937 |
0.112 |
|
2001 |
Tamiz AP, Bandyopadhyay BC, Zhang J, Flippen-Anderson JL, Zhang M, Wang CZ, Johnson KM, Tella S, Kozikowski AP. Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors. Journal of Medicinal Chemistry. 44: 1615-22. PMID 11334571 DOI: 10.1021/jm000552s |
0.111 |
|
1980 |
Flippen-Anderson JL, Karle I, Huisgen R, Reißig H. Trimerisierung eines Azomethin-imins durch drei aufeinanderfolgende 1,3-dipolare Cycloadditionen Angewandte Chemie. 92: 936-937. DOI: 10.1002/Ange.19800921114 |
0.111 |
|
1991 |
Paciorek KJL, Nakahara JH, Hoferkamp LA, George C, Flippen-Anderson JL, Gilardi R, Schmidt WR. Reactions of tris[bis(trimethylsilyl)amino]aluminum with ammonia and pyrolysis studies Chemistry of Materials. 3: 82-87. DOI: 10.1021/Cm00013A021 |
0.11 |
|
2000 |
Zhao L, Johnson KM, Zhang M, Flippen-Anderson J, Kozikowski AP. Chemical synthesis and pharmacology of 6- and 7-hydroxylated 2-carbomethoxy-3-(p-tolyl)tropanes: antagonism of cocaine's locomotor stimulant effects. Journal of Medicinal Chemistry. 43: 3283-94. PMID 10966747 DOI: 10.1021/jm000141b |
0.11 |
|
1990 |
Pramod K, Eaton PE, Gilardi R, Flippen-Anderson JL. Regiospecific oxidation of binor S and acid-catalyzed rearrangement of the product to the first example of a pentacyclo[6.6.0.05,14.07,12.09,13]tetradecane Journal of Organic Chemistry. 55: 6105-6107. DOI: 10.1021/Jo00312A014 |
0.11 |
|
1996 |
Yamada K, Rice KC, Flippen-Anderson JL, Eissenstat MA, Ward SJ, Johnson MR, Howlett AC. (Aminoalkyl)indole isothiocyanates as potential electrophilic affinity ligands for the brain cannabinoid receptor. Journal of Medicinal Chemistry. 39: 1967-74. PMID 8642555 DOI: 10.1021/jm950932r |
0.11 |
|
1998 |
Nielsen AT, Chafin AP, Christian SL, Moore DW, Nadler MP, Nissan RA, Vanderah DJ, Gilardi RD, George CF, Flippen-Anderson JL. Synthesis of polyazapolycyclic caged polynitramines Tetrahedron. 54: 11793-11812. DOI: 10.1016/S0040-4020(98)83040-8 |
0.109 |
|
2001 |
Flippen-Anderson JL, Axenrod T, Sun J, Gilardi RD. 3,7-Di-tert-butyl-1,5-dinitro-3,7-diazabicyclo[3.3.1]nonane Acta Crystallographica Section E Structure Reports Online. 57: o1128-o1129. DOI: 10.1107/S1600536801018153 |
0.109 |
|
1988 |
CHRZANOWSKA M, SCHOENENBERGER B, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: Mammalian Alkaloids: Configurations of Optically Active Salsoline- and 3′,4′-Dideoxynorlaudanosoline-1-carboxylic Acids. Cheminform. 19. DOI: 10.1002/CHIN.198805346 |
0.108 |
|
1986 |
Schönenberger B, Brossi A, George C, Flippen-Anderson JL. Preparation of Optically Active Secondary Amines by Thermal Decomposition of (Methylbenzyl)urea Analogs: Absolute Configuration of (+)- and (−)-Mecamylamine. Preliminary Communication Helvetica Chimica Acta. 69: 283-287. DOI: 10.1002/Hlca.19860690205 |
0.108 |
|
2006 |
Kozikowski AP, Zhao L, Zhang A, Wang CZ, Flippen-Anderson J, Johnson KM. Structural remodeling of cocaine: design and synthesis of trisubstituted cyclopropanes as selective serotonin reuptake inhibitors. Chemmedchem. 1: 58-65. PMID 16892336 DOI: 10.1002/cmdc.200500016 |
0.107 |
|
2006 |
Kozikowski AP, Zhao L, Zhang A, Wang CZ, Flippen-Anderson J, Johnson KM. Structural Remodeling of Cocaine: Design and Synthesis of Trisubstituted Cyclopropanes as Selective Serotonin Reuptake Inhibitors. Cheminform. 37. DOI: 10.1002/CHIN.200622196 |
0.107 |
|
2010 |
OLAH GA, SASSAMAN MB, ZUANIC M, RAO CB, PRAKASH GKS, GILARDI R, FLIPPEN-ANDERSON J, GEORGE C. ChemInform Abstract: Considered Synthetic Method and Reactions. Part 165. One-Step Preparation of Hydrazinium Nitrates from Tertiary Amines and Azaarenes with H2N-O-SO3H/Ba(NO3)2 and Conversion to Energetic Amine-Nitroimides. Cheminform. 23: no-no. DOI: 10.1002/chin.199233136 |
0.107 |
|
1992 |
Olah GA, Sassaman MB, Zuanic M, Rao CB, Prakash GKS, Gilardi R, Flippen-Anderson J, George C. Considered synthetic methods and reactions. Part 165. One-step preparation of hydrazinium nitrates from tertiary amines and azaarenes with hydroxylamine-O-sulfonic acid/barium nitrate/barium oxide and conversion to energetic amine-nitroimides The Journal of Organic Chemistry. 57: 1585-1588. DOI: 10.1021/Jo00031A046 |
0.105 |
|
2003 |
Zhao S, Liao X, Wang T, Flippen-Anderson J, Cook JM. The Enantiospecific, Stereospecific Total Synthesis of the Ring-A Oxygenated Sarpagine Indole Alkaloids (+)-Majvinine (Ia), (+)-10-Methoxyaffinisine (Ib), and (+)-Na-Methylsarpagine (Ic), as Well as the Total Synthesis of the Alstonia Bisindole Alkaloid Macralstonidine (II). Cheminform. 34. DOI: 10.1002/CHIN.200349193 |
0.105 |
|
2010 |
VEDACHALAM M, RAMAKRISHNAN VT, BOYER JH, DAGLEY IJ, NELSON KA, ADOLPH HG, GILARDI R, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: Facile Synthesis and Nitration of cis-syn-cis-2,6-Dioxodecahydro-1H,5H- diimidazo(4,5-b:4′,5′-e)pyrazine. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199139179 |
0.105 |
|
2001 |
Deschamps JR, George C, Flippen-Anderson JL, Spencer G. A newCryptocaryalactone Acta Crystallographica Section E Structure Reports Online. 57: o648-o649. DOI: 10.1107/S1600536801010273 |
0.104 |
|
2010 |
Jarvis BB, Taha Çömezoglu F, Lee Y, Flippen-Anderson JL, Gilardi RD, George CF. Novel Macrocyclic Trichothecenes from Myrothecium Roridum Bulletin Des SociéTéS Chimiques Belges. 95: 681-697. DOI: 10.1002/BSCB.19860950901 |
0.103 |
|
1990 |
NIELSEN AT, NISSAN RA, VANDERAH DJ, COON CL, GILARDI RD, GEORGE CFJ, FLIPPEN-ANDERSON JL. ChemInform Abstract: Polyazapolycyclics by Condensation of Aldehydes with Amines. Part 2. Formation of 2,4,6,8,10,12-Hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo-(5.5.0.05,9.03,11)dodecanes from Glyoxal and Benzylamines. Cheminform. 21. DOI: 10.1002/CHIN.199032201 |
0.103 |
|
2017 |
Burley SK, Gabanyi MJ, Sala R, Westbrook JD, Flippen-Anderson JL, Deshmukh I, Berman HM. BioSync: an online resource for X-ray facilities worldwide Acta Crystallographica Section a Foundations and Advances. 73: C1216-C1216. DOI: 10.1107/S2053273317083589 |
0.101 |
|
1987 |
Chrzanowska M, Schönenberger B, Brossi A, Flippen-Anderson JL. Mammalian Alkaloids: Configurations of Optically Active Salsoline- and 3′,4′-Dideoxynorlaudanosoline-1-carboxylic Acids Helvetica Chimica Acta. 70: 1721-1731. DOI: 10.1002/HLCA.19870700707 |
0.101 |
|
2000 |
Gu XH, Yu H, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. Journal of Medicinal Chemistry. 43: 4868-76. PMID 11123996 DOI: 10.1021/Jm000329V |
0.101 |
|
1984 |
SCHMIDHAMMER H, BROSSI A, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: APOMORPHINANS FROM ISOQUINOLINES: GREWE CYCLIZATION OF 1-(2-HYDROXYBENZYL)-N-METHYLOCTAHYDROISOQUINOLINE AND ITS O-METHYL ETHER Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198411066 |
0.099 |
|
2010 |
DAGLEY IJ, FLIPPEN-ANDERSON JL. ChemInform Abstract: Synthesis of Cyclic Nitramines from Products of the Cyclocondensation Reaction of Guanidine with 2,3,5,6-Tetrahydroxypiperazine-1,4- dicarbaldehyde. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199515195 |
0.099 |
|
2005 |
Deshpande N, Addess KJ, Bluhm WF, Merino-Ott JC, Townsend-Merino W, Zhang Q, Knezevich C, Xie L, Chen L, Feng Z, Green RK, Flippen-Anderson JL, Westbrook J, Berman HM, Bourne PE. The RCSB Protein Databa Bank: A redesigned query system and relational database based on the mmCIF schema Nucleic Acids Research. 33: D233-D237. PMID 15608185 DOI: 10.1093/Nar/Gki057 |
0.099 |
|
1990 |
MARCHAND AP, ANNAPURNA P, TAYLOR RW, SIMMONS DL, WATSON WH, NAGL A, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C. ChemInform Abstract: Unusual Behavior of 3,4:10,11-Bis(2′,3′-quinolino)tricyclo(6.3.0.02,6)undecane Upon Attempted Monoprotonation with Triflic Acid. Cheminform. 21. DOI: 10.1002/CHIN.199047144 |
0.098 |
|
1981 |
Schwab AW, Gilardi RD, Flippen-anderson JL. CONFIGURATION OF OCTADECYL TETRASULFIDE Phosphorus and Sulfur and the Related Elements. 10: 123-126. DOI: 10.1080/03086648108078280 |
0.095 |
|
2010 |
BAUM K, BIGELOW SS, NGUYEN NV, ARCHIBALD TG, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Synthesis and Reactions of 1,1-Diiododinitroethylene. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199225047 |
0.094 |
|
2006 |
Bourne PE, Bluhm WF, Deshpande N, Zhang Q, Berman HM, Flippen-Anderson JL. The research collaboratory for structural bioinformatics protein data bank Comprehensive Medicinal Chemistry Ii. 3: 373-388. |
0.094 |
|
2010 |
FLIPPEN-ANDERSON JL, GILARDI RD, PITT AM, WILSON WS. ChemInform Abstract: Synthesis and Explosive Properties of Benzotriazoles. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199223168 |
0.094 |
|
2003 |
Cao H, Flippen-Anderson J, Cook JM. The synthesis of a dicyclopenta[a,e]pentalene via a molybdenum hexacarbonyl-mediated tandem allenic Pauson-Khand reaction. Journal of the American Chemical Society. 125: 3230-1. PMID 12630875 DOI: 10.1021/Ja021159+ |
0.091 |
|
2010 |
BRZOSTOWSKA M, BROSSI A, FLIPPEN-ANDERSON JL. ChemInform Abstract: Chiral Prodyes: Synthesis and Full Characterization of (S)-1- Phenylethylamides of the Optically Active O-Methyldihydrofluoresceins. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199204178 |
0.091 |
|
2010 |
BAUM K, ARCHIBALD TG, TZENG D, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Synthesis and Properties of 1,2-Difluorodinitroethylene. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199131113 |
0.091 |
|
2004 |
Yu H, Kim IJ, Folk JE, Tian X, Rothman RB, Baumann MH, Dersch CM, Flippen-Anderson JL, Parrish D, Jacobson AE, Rice KC. Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters. Journal of Medicinal Chemistry. 47: 2624-34. PMID 15115403 DOI: 10.1021/Jm0305873 |
0.09 |
|
1985 |
West DX, Ahrweiler PM, Ertem G, Scovill JP, Klayman DL, Flippen-Anderson JL, Gilardi R, George C, Pannell LK. Iron(III) complexes of some thiosemicarbazones derived from 2-acetylpyridine, its 6-methyl derivative and itsN-oxide Transition Metal Chemistry. 10: 264-270. DOI: 10.1007/Bf00621084 |
0.09 |
|
2005 |
Deng H, Gifford AN, Zvonok AM, Cui G, Li X, Fan P, Deschamps JR, Flippen-Anderson JL, Gatley SJ, Makriyannis A. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. Journal of Medicinal Chemistry. 48: 6386-92. PMID 16190764 DOI: 10.1021/Jm050135L |
0.089 |
|
1983 |
Schmidhammer H, Brossi A, Flippen-Anderson JL, Gilardi R. Apomorphinans from Isoquinolines:Grewe cyclization of 1-(2-hydroxybenzyl)-N-methyloctahydroisoquinoline and itsO-methyl ether Helvetica Chimica Acta. 66: 2437-2442. DOI: 10.1002/HLCA.19830660807 |
0.088 |
|
2004 |
Yu J, Wang T, Liu X, Deschamps J, Flippen-Anderson J, Liao X, Cook JM. General Approach for the Synthesis of Sarpagine Indole Alkaloids. Enantiospecific Total Synthesis of (+)-Vellosimine (Ia), (+)-Normacusine B (Ib), (-)-Alkaloid Q3 (II), (-)-Panarine (III), (+)-Na-Methylvellosimine (IVa), and (+)-Na-Methyl-16-epipericyclivine (IVb). Cheminform. 35. DOI: 10.1002/chin.200406169 |
0.088 |
|
1985 |
KEREKES P, BROSSI A, FLIPPEN-ANDERSON JL, CHIGNELL CF. ChemInform Abstract: ESTERS OF 1-O-DEMETHYLTHIOCOLCHICINES: FORMATION OF ISOMERS IN CHLOROFORM SOLUTION Chemischer Informationsdienst. 16. DOI: 10.1002/CHIN.198535083 |
0.086 |
|
1990 |
Nielsen AT, Nissan RA, Vanderah DJ, Coon CL, Gilardi RD, George CF, Flippen-Anderson J. Polyazapolycyclics by condensation of aldehydes with amines. 2. Formation of 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05.9.03,11]dodecanes from glyoxal and benzylamines The Journal of Organic Chemistry. 55: 1459-1466. DOI: 10.1021/JO00292A015 |
0.084 |
|
1986 |
SCHOENENBERGER B, BROSSI A, GEORGE C, FLIPPEN-ANDERSON JL. ChemInform Abstract: Preparation of Optically Active Secondary Amines by Thermal Decomposition of (Methylbenzyl)urea Analogs: Absolute Configuration of (+)- and (-)-Mecamylamine. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198624331 |
0.083 |
|
2001 |
Gilardi RD, Axenrod T, Sun J, Flippen-Anderson JL. 1,3,5,7-tetranitro-3,7-diazabicyclo[3.3.1]nonane Acta Crystallographica Section E Structure Reports Online. 57: o1107-o1108. DOI: 10.1107/S1600536801017780 |
0.083 |
|
1991 |
Vedachalam M, Ramakrishnan VT, Boyer JH, Dagley IJ, Nelson KA, Adolph HG, Gilardi R, George C, Flippen-Anderson JL. Facile synthesis and nitration of cis-syn-cis-2,6-dioxodecahydro-1H,5H-diimidazo[4,5-b:4',5'-e]pyrazine The Journal of Organic Chemistry. 56: 3413-3419. DOI: 10.1021/JO00010A043 |
0.082 |
|
1985 |
Kerekes P, Brossi A, Flippen-Anderson JL, Chignell CF. Esters of 1-O-Demethylthiocolchicines: Formation of Isomers in Chloroform Solution Helvetica Chimica Acta. 68: 571-580. DOI: 10.1002/HLCA.19850680306 |
0.075 |
|
1991 |
Baum K, Archibald TG, Tzeng D, Gilardi R, Flippen-Anderson JL, George C. Synthesis and properties of 1,2-difluorodinitroethylene The Journal of Organic Chemistry. 56: 537-539. DOI: 10.1021/JO00002A011 |
0.074 |
|
1998 |
Smith MP, Johnson KM, Zhang M, Flippen-Anderson JL, Kozikowski AP. Tuning the selectivity of monoamine transporter inhibitors by the stereochemistry of the nitrogen lone pair [2] Journal of the American Chemical Society. 120: 9072-9073. DOI: 10.1021/ja981423s |
0.072 |
|
2000 |
Tamiz AP, Smith MP, Enyedy I, Flippen-Anderson J, Zhang M, Johnson KM, Kozikowski AP. ChemInform Abstract: Synthesis and Biological Evaluation of 1-Azabicyclo[3.2.1]octanes: New Dopamine Transporter Inhibitors. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200044172 |
0.072 |
|
2010 |
BAUM K, NGUYEN NV, GILARDI R, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: Nitration of 1,1-Diamino-2,2-dinitroethylenes. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199245118 |
0.072 |
|
2010 |
SAAVEDRA JE, DUNAMS TM, FLIPPEN-ANDERSON JL, KEEFER LK. ChemInform Abstract: Secondary Amine/Nitric Oxide Complex Ions, R2N(N(O)NO)-. O- Functionalization Chemistry. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199310166 |
0.069 |
|
1980 |
Flippen-Anderson JL, Karle I, Huisgen R, Reissig H. Trimerization of an Azomethine Imine by Three Successive 1,3-Dipolar Cycloaddition Reactions Angewandte Chemie International Edition in English. 19: 906-907. DOI: 10.1002/Anie.198009061 |
0.069 |
|
2002 |
Gilardi R, Flippen-Anderson JL, Evans R. cis-2,4,6,8-Tetranitro-1H,5H-2,4,6,8-tetraazabicyclo[3.3.0]octane, the energetic compound `bicyclo-HMX' Acta Crystallographica Section E Structure Reports Online. 58: o972-o974. DOI: 10.1107/S1600536802013582 |
0.068 |
|
2003 |
Sakamuri S, Enyedy IJ, Zaman WA, Tella SR, Kozikowski AP, Flippen-Anderson JL, Farkas T, Johnson KM, Wang S. 2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors. Bioorganic & Medicinal Chemistry. 11: 1123-36. PMID 12614900 DOI: 10.1016/S0968-0896(02)00450-9 |
0.067 |
|
2000 |
Sakamuri S, George C, Flippen-Anderson J, Kozikowski AP. Synthesis of novel spirocyclic cocaine analogs using the Suzuki coupling Tetrahedron Letters. 41: 2055-2058. DOI: 10.1016/S0040-4039(00)00113-1 |
0.065 |
|
1984 |
LUO X, YEH HJC, BROSSI A, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: THE CHEMISTRY OF DRUGS. PART IV. CONFIGURATIONS OF ANTIMALARIALS DERIVED FROM M QINGHAOSU: DIHYDROQINGHAOSU, ARTEMETHER, AND ARTESUNIC ACID Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198452374 |
0.065 |
|
2001 |
Qiao L, Zhao LY, Rong SB, Wu XW, Wang S, Fujii T, Kazanietz MG, Rauser L, Savage J, Roth BL, Flippen-Anderson J, Kozikowski AP. Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth. Bioorganic & Medicinal Chemistry Letters. 11: 955-9. PMID 11327599 DOI: 10.1016/S0960-894X(01)00097-X |
0.064 |
|
1984 |
Luo X, Yeh HJC, Brossi A, Flippen-Anderson JL, Gillardi R. The chemistry of drugs part IV, Configurations of antimalarials derived from qinghaosu: Dihydroqingyhaosu, artemether, and artesunic acid Helvetica Chimica Acta. 67: 1515-1522. DOI: 10.1002/HLCA.19840670615 |
0.064 |
|
1992 |
Saavedra JE, Dunams TM, Flippen-Anderson JL, Keefer LK. Secondary amine/nitric oxide complex ions, R2N[N(O)NO]-. O-Functionalization chemistry The Journal of Organic Chemistry. 57: 6134-6138. DOI: 10.1021/JO00049A017 |
0.063 |
|
1989 |
SRIVASTAVA S, MARCHAND AP, VIDYASAGAR V, FLIPPEN-ANDERSON JL, GILARDI R, GEORGE C, ZACHWIEJA Z, LE NOBLE WJ. ChemInform Abstract: Pressure Effect on the Product Distribution in Competing Reactions: Formation of a Bis Diels-Alder Adduct via an Aromatizable Intermediate. Cheminform. 20. DOI: 10.1002/CHIN.198929062 |
0.061 |
|
2002 |
Flippen-Anderson JL, Deschamps JR, Brossi A, Greig NH. 2-Hydroxybenzoic acid salt of physostigmine Acta Crystallographica Section E Structure Reports Online. 58: o853-o855. DOI: 10.1107/S1600536802012278 |
0.058 |
|
1980 |
THOMPSON MJ, MANDAVA N, FLIPPEN-ANDERSON JL, WORLEY JF, DUTKY SR, ROBBINS WE, LUSBY W. ChemInform Abstract: SYNTHESIS OF BRASSINO STEROIDS: NEW PLANT-GROWTH-PROMOTING STEROIDS Chemischer Informationsdienst. 11. DOI: 10.1002/CHIN.198018298 |
0.057 |
|
1991 |
Scovill JP, Klayman DL, Flippen-anderson JL, Gilardi R. 1,3,4-THIADIAZOLES FROM THIOSEMICARBAZIDES Phosphorus, Sulfur, and Silicon and the Related Elements. 63: 273-281. DOI: 10.1080/10426509108036830 |
0.053 |
|
1992 |
Chaykovsky M, Koppes WM, Russell TP, Gilardi R, George C, Flippen-Anderson JL. The isolation of a bi(2,4,6,8-tetraazabicyclo[3.3.0]octane) from the reaction of glyoxal with benzylamine The Journal of Organic Chemistry. 57: 4295-4297. DOI: 10.1021/Jo00041A044 |
0.051 |
|
1989 |
Srivastava S, Marchand AP, Vidyasagar V, Flippen-Anderson JL, Gilardi R, George C, Zachwieja Z, Le Noble WJ. Pressure effect on the product distribution in competing reactions: formation of a bis Diels-Alder adduct via an aromatizable intermediate The Journal of Organic Chemistry. 54: 247-249. DOI: 10.1021/JO00262A052 |
0.051 |
|
2002 |
Deschamps JR, Flippen-Anderson JL, George C. The search for a better analgesic Acta Crystallographica Section a Foundations of Crystallography. 58: c36-c36. DOI: 10.1107/S0108767302086543 |
0.049 |
|
1990 |
MORIARTY RM, KHOSROWSHAHI JS, MILLER RS, FLIPPEN-ANDERSON JL, GILARDI R. ChemInform Abstract: Free-Radical Arylation of Cubane Using Cubyl Lead Acylates. Cheminform. 21. DOI: 10.1002/CHIN.199011132 |
0.046 |
|
1979 |
Thompson MJ, Mandava N, Flippen-Anderson JL, Worley JF, Dutky SR, Robbins WE, Lusby W. Synthesis of brassino steroids: new plant-growth-promoting steroids The Journal of Organic Chemistry. 44: 5002-5004. DOI: 10.1021/jo00394a066 |
0.046 |
|
1985 |
Jarvis BB, Lee YW, Yatawara CS, Mazzocchi DB, Flippen-Anderson JL, Gilardi R, George C. 7 alpha-hydroxytrichodermol, a new trichothecene from Myrothecium roridum. Applied and Environmental Microbiology. 50: 1225-8. PMID 4091555 DOI: 10.1128/Aem.50.5.1225-1228.1985 |
0.043 |
|
2003 |
Flippen-Anderson JL, George C, Deschamps JR. Molecular approaches to treatments for cocaine abuse Journal of Molecular Structure. 647: 259-267. DOI: 10.1016/S0022-2860(02)00532-X |
0.038 |
|
2001 |
Zheng T, Flippen-Anderson J, Yu P, Wang T, Mirghani R, Cook JM. Stereocontrolled conversion of quinine into 10(R),11-dihydroxydihydroquinine via the sharpless osmylation process. The Journal of Organic Chemistry. 66: 1509-11. PMID 11312991 DOI: 10.1021/Jo0015321 |
0.032 |
|
2002 |
Gilardi RD, Flippen-Anderson JL. Twins and multiple polymorphs occurring in energetic organic materials Acta Crystallographica Section a Foundations of Crystallography. 58: c232-c232. DOI: 10.1107/S0108767302094308 |
0.032 |
|
1985 |
Gilardi R, Flippen-Anderson JL. Synthetic high-pressure lubricants: dioctadecyl trisulfide (I), C36H74S3, and dioctadecyl tetrasulfide (II), C36H74S4 Acta Crystallographica Section C Crystal Structure Communications. 41: 72-76. DOI: 10.1107/S0108270185002827 |
0.031 |
|
2002 |
Flippen-Anderson J, Deschamps JR, George C. Data quality and the modern CCD detector Acta Crystallographica Section a Foundations of Crystallography. 58: c260-c260. DOI: 10.1107/S0108767302095399 |
0.012 |
|
1986 |
Pavanand K, Nutakul W, Dechatiwongse T, Yoshihira K, Yongvanitchit K, Scovill JP, Flippen-Anderson JL, Gilardi R, George C, Kanchanapee P. In vitro antimalarial activity of Brucea javanica against multi-drug resistant Plasmodium falciparum. Planta Medica. 108-11. PMID 3523552 |
0.01 |
|
1982 |
Flippen-Anderson JL, Mills FD. Stereochemistry of a complex diindenopyradione Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 38: 495-498. DOI: 10.1107/S0567740882003264 |
0.01 |
|
1981 |
Flippen-Anderson JL, Gilardi R. Structure–activity relationships in brassino steroids Acta Crystallographica Section a Foundations of Crystallography. 37: C57-C57. DOI: 10.1107/S0108767381097869 |
0.01 |
|
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