Robert Stanley Hodges - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
 1974- Biochemistry University of Alberta, Edmonton, Alberta, Canada 
Area:
Protein Folding and Stability
Website:
http://wishart.biology.ualberta.ca/pence/en/index.php?bios/r_hodges

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mant CT, Jiang Z, Gera L, Davis T, Nelson K, Bevers S, Hodges RS. De novo designed amphipathic α-helical antimicrobial peptides incorporating Dab and Dap residues on the polar face to treat the Gram-negative pathogen, Acinetobacter baumannii. Journal of Medicinal Chemistry. PMID 30848594 DOI: 10.1021/acs.jmedchem.8b01785  1
2018 Mant CT, Byars A, Ankarlo S, Jiang Z, Hodges RS. Separation of highly charged (+5 to +10) amphipathic α-helical peptide standards by cation-exchange and reversed-phase high-performance liquid chromatography. Journal of Chromatography. A. PMID 30220427 DOI: 10.1016/j.chroma.2018.09.003  1
2017 Jiang Z, Mant CT, Vasil M, Hodges RS. Role of positively charged residues on the polar and non-polar faces of amphipathic α-helical antimicrobial peptides (AMPs) on specificity and selectivity for Gram-negative pathogens. Chemical Biology & Drug Design. PMID 28636788 DOI: 10.1111/cbdd.13058  1
2017 Murschel F, Fortier C, Jolicoeur M, Hodges RS, De Crescenzo G. Two Complementary Approaches for the Controlled Release of Biomolecules Immobilized via Coiled-coil Interactions: Peptide Core Mutations and Multivalent Presentation. Biomacromolecules. PMID 28122454 DOI: 10.1021/acs.biomac.6b01830  1
2016 Romantsov T, Culham DE, Caplan T, Garner J, Hodges RS, Wood JM. ProP-ProP and ProP-phospholipid interactions determine the subcellular distribution of osmosensing transporter ProP in Escherichia coli. Molecular Microbiology. PMID 27802568 DOI: 10.1111/mmi.13569  1
2016 Mant CT, Hodges RS. Separation of Peptides on HALO 2-Micron Particles. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 85: 11.6.1-11.6.16. PMID 27479502 DOI: 10.1002/cpps.12  1
2016 Jiang Z, Gera L, Mant CT, Hirsch B, Yan Z, Qian Z, Holmes KV, Shortt JA, Pollock DD, Hodges RS. Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza a viruses. Biopolymers. PMID 26799790 DOI: 10.1002/bip.22808  1
2014 Avdieiev S, Gera L, Havrylyuk D, Hodges RS, Lesyk R, Ribrag V, Vassetzky Y, Kavsan V. Bradykinin antagonists and thiazolidinone derivatives as new potential anti-cancer compounds. Bioorganic & Medicinal Chemistry. 22: 3815-23. PMID 25012567 DOI: 10.1016/j.bmc.2014.06.046  1
2014 Jiang Z, Vasil AI, Vasil ML, Hodges RS. "Specificity Determinants" Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 Against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa. Pharmaceuticals (Basel, Switzerland). 7: 366-91. PMID 24670666 DOI: 10.3390/ph7040366  1
2014 Abraham T, Prenner EJ, Lewis RN, Mant CT, Keller S, Hodges RS, McElhaney RN. Structure-activity relationships of the antimicrobial peptide gramicidin S and its analogs: aqueous solubility, self-association, conformation, antimicrobial activity and interaction with model lipid membranes. Biochimica Et Biophysica Acta. 1838: 1420-9. PMID 24388950 DOI: 10.1016/j.bbamem.2013.12.019  1
2014 Kirwan JP, Hodges RS. Transmission of stability information through the N-domain of tropomyosin is interrupted by a stabilizing mutation (A109L) in the hydrophobic core of the stability control region (residues 97-118). The Journal of Biological Chemistry. 289: 4356-66. PMID 24362038 DOI: 10.1074/jbc.M113.507236  1
2014 Huang Y, Pan L, Zhao L, Mant CT, Hodges RS, Chen Y. Structure-guided RP-HPLC chromatography of diastereomeric α-helical peptide analogs substituted with single amino acid stereoisomers. Biomedical Chromatography : Bmc. 28: 511-7. PMID 24127254 DOI: 10.1002/bmc.3061  1
2013 Mant CT, Jiang Z, Boyes BE, Hodges RS. An improved approach to hydrophilic interaction chromatography of peptides: salt gradients in the presence of high isocratic acetonitrile concentrations. Journal of Chromatography. A. 1277: 15-25. PMID 23332786 DOI: 10.1016/j.chroma.2012.12.044  1
2012 Lanaspa MA, Cicerchi C, Garcia G, Li N, Roncal-Jimenez CA, Rivard CJ, Hunter B, Andrés-Hernando A, Ishimoto T, Sánchez-Lozada LG, Thomas J, Hodges RS, Mant CT, Johnson RJ. Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver. Plos One. 7: e48801. PMID 23152807 DOI: 10.1371/journal.pone.0048801  1
2012 Zajdowicz S, Haller JC, Krafft AE, Hunsucker SW, Mant CT, Duncan MW, Hodges RS, Jones DN, Holmes RK. Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae. Plos One. 7: e34591. PMID 22514641 DOI: 10.1371/journal.pone.0034591  1
2012 Mant CT, Hodges RS. Design of peptide standards with the same composition and minimal sequence variation to monitor performance/selectivity of reversed-phase matrices. Journal of Chromatography. A. 1230: 30-40. PMID 22326185 DOI: 10.1016/j.chroma.2012.01.053  1
2011 Baumgartner HK, Beeman N, Hodges RS, Neville MC. A D-peptide analog of the second extracellular loop of claudin-3 and -4 leads to mislocalized claudin and cellular apoptosis in mammary epithelial cells. Chemical Biology & Drug Design. 77: 124-36. PMID 21266016 DOI: 10.1111/j.1747-0285.2010.01061.x  1
2011 Jiang Z, Vasil AI, Gera L, Vasil ML, Hodges RS. Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio. Chemical Biology & Drug Design. 77: 225-40. PMID 21219588 DOI: 10.1111/j.1747-0285.2011.01086.x  1
2011 Jiang Z, Higgins MP, Whitehurst J, Kisich KO, Voskuil MI, Hodges RS. Anti-tuberculosis activity of α-helical antimicrobial peptides: de novo designed L- and D-enantiomers versus L- and D-LL-37. Protein and Peptide Letters. 18: 241-52. PMID 20858205  1
2010 Mant CT, Cepeniene D, Hodges RS. Reversed-phase HPLC of peptides: Assessing column and solvent selectivity on standard, polar-embedded and polar endcapped columns. Journal of Separation Science. 33: 3005-21. PMID 21038458 DOI: 10.1002/jssc.201000518  1
2010 Hackbarth C, Hodges RS. Synthetic peptide vaccine development: designing dual epitopes into a single pilin peptide immunogen generates antibody cross-reactivity between two strains of Pseudomonas aeruginosa. Chemical Biology & Drug Design. 76: 293-304. PMID 20807222 DOI: 10.1111/j.1747-0285.2010.01021.x  0.01
2010 Gambin Y, Reffay M, Sierecki E, Homblé F, Hodges RS, Gov NS, Taulier N, Urbach W. Variation of the lateral mobility of transmembrane peptides with hydrophobic mismatch. The Journal of Physical Chemistry. B. 114: 3559-66. PMID 20170092 DOI: 10.1021/jp911354y  1
2010 Kirwan JP, Hodges RS. Critical interactions in the stability control region of tropomyosin. Journal of Structural Biology. 170: 294-306. PMID 20144718 DOI: 10.1016/j.jsb.2010.01.020  1
2009 Mant CT, Kovacs JM, Kim HM, Pollock DD, Hodges RS. Intrinsic amino acid side-chain hydrophilicity/hydrophobicity coefficients determined by reversed-phase high-performance liquid chromatography of model peptides: comparison with other hydrophilicity/hydrophobicity scales. Biopolymers. 92: 573-95. PMID 19795449 DOI: 10.1002/bip.21316  1
2009 Hodges RS, Mills J, McReynolds S, Kirwan JP, Tripet B, Osguthorpe D. Identification of a unique "stability control region" that controls protein stability of tropomyosin: A two-stranded alpha-helical coiled-coil. Journal of Molecular Biology. 392: 747-62. PMID 19627992 DOI: 10.1016/j.jmb.2009.07.039  1
2009 Kao DJ, Hodges RS. Advantages of a synthetic peptide immunogen over a protein immunogen in the development of an anti-pilus vaccine for Pseudomonas aeruginosa Chemical Biology and Drug Design. 74: 33-42. PMID 19519742 DOI: 10.1111/j.1747-0285.2009.00825.x  1
2009 Jiang Z, Vasil AI, Hale J, Hancock RE, Vasil ML, Hodges RS. Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Advances in Experimental Medicine and Biology. 611: 561-2. PMID 19400313  1
2009 Yan Z, Holmes KV, Hodges RS. Expression and characterization of recombinant S2 subunit of SARS-coronavirus S fusion protein. Advances in Experimental Medicine and Biology. 611: 153-4. PMID 19400136  1
2009 Kirwan JP, Kwok SC, McReynolds S, Mills J, Osguthorpe D, Hodges RS. Unique role of clusters of electrostatic attractions in controlling the stability of two-stranded alpha-helical coiled-coils. Advances in Experimental Medicine and Biology. 611: 77-8. PMID 19400101 DOI: 10.1007/978-0-387-73657-0_34  1
2009 Jelokhani-Niaraki M, Kondejewski LH, Wheaton LC, Hodges RS. Effect of ring size on conformation and biological activity of cyclic cationic antimicrobial peptides. Journal of Medicinal Chemistry. 52: 2090-7. PMID 19278255 DOI: 10.1021/jm801648n  1
2009 Pimentel TA, Yan Z, Jeffers SA, Holmes KV, Hodges RS, Burkhard P. Peptide nanoparticles as novel immunogens: design and analysis of a prototypic severe acute respiratory syndrome vaccine. Chemical Biology & Drug Design. 73: 53-61. PMID 19152635 DOI: 10.1111/j.1747-0285.2008.00746.x  1
2008 Yu B, Davis EM, Hodges RS, Irvin RT, Li DY. Surface nanocrystallization of stainless steel for reduced biofilm adherence. Nanotechnology. 19: 335101. PMID 21730615 DOI: 10.1088/0957-4484/19/33/335101  1
2008 Jiang Z, Kullberg BJ, van der Lee H, Vasil AI, Hale JD, Mant CT, Hancock RE, Vasil ML, Netea MG, Hodges RS. Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides. Chemical Biology & Drug Design. 72: 483-95. PMID 19090916 DOI: 10.1111/j.1747-0285.2008.00728.x  1
2008 Mant CT, Hodges RS. Mixed-mode hydrophilic interaction/cation-exchange chromatography (HILIC/CEX) of peptides and proteins. Journal of Separation Science. 31: 2754-73. PMID 18668504 DOI: 10.1002/jssc.200800243  1
2008 Jelokhani-Niaraki M, Hodges RS, Meissner JE, Hassenstein UE, Wheaton L. Interaction of gramicidin S and its aromatic amino-acid analog with phospholipid membranes. Biophysical Journal. 95: 3306-21. PMID 18621820 DOI: 10.1529/biophysj.108.137471  1
2008 Mant CT, Hodges RS. Mixed-mode hydrophilic interaction/cation-exchange chromatography: separation of complex mixtures of peptides of varying charge and hydrophobicity. Journal of Separation Science. 31: 1573-84. PMID 18461566 DOI: 10.1002/jssc.200700619  1
2008 Jiang Z, Vasil AI, Hale JD, Hancock RE, Vasil ML, Hodges RS. Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides. Biopolymers. 90: 369-83. PMID 18098173 DOI: 10.1002/bip.20911  1
2008 Tsatskis Y, Kwok SC, Becker E, Gill C, Smith MN, Keates RA, Hodges RS, Wood JM. Core residue replacements cause coiled-coil orientation switching in vitro and in vivo: structure-function correlations for osmosensory transporter ProP. Biochemistry. 47: 60-72. PMID 18076193 DOI: 10.1021/bi7018173  1
2007 Mant CT, Chen Y, Yan Z, Popa TV, Kovacs JM, Mills JB, Tripet BP, Hodges RS. HPLC analysis and purification of peptides. Methods in Molecular Biology (Clifton, N.J.). 386: 3-55. PMID 18604941 DOI: 10.1007/978-1-59745-430-8_1  1
2007 Kao DJ, Churchill ME, Irvin RT, Hodges RS. Animal protection and structural studies of a consensus sequence vaccine targeting the receptor binding domain of the type IV pilus of Pseudomonas aeruginosa. Journal of Molecular Biology. 374: 426-42. PMID 17936788 DOI: 10.1016/j.jmb.2007.09.032  1
2007 Popa TV, Mant CT, Hodges RS. Ion-interaction CZE: the presence of high concentrations of ion-pairing reagents demonstrates the complex mechanisms involved in peptide separations. Electrophoresis. 28: 2181-90. PMID 17557361 DOI: 10.1002/elps.200600729  1
2007 Smith MN, Kwok SC, Hodges RS, Wood JM. Structural and functional analysis of ProQ: an osmoregulatory protein of Escherichia coli. Biochemistry. 46: 3084-95. PMID 17319698 DOI: 10.1021/bi6023786  1
2007 Tripet B, Cepeniene D, Kovacs JM, Mant CT, Krokhin OV, Hodges RS. Requirements for prediction of peptide retention time in reversed-phase high-performance liquid chromatography: hydrophilicity/hydrophobicity of side-chains at the N- and C-termini of peptides are dramatically affected by the end-groups and location. Journal of Chromatography. A. 1141: 212-25. PMID 17187811 DOI: 10.1016/j.chroma.2006.12.024  1
2007 Chen Y, Guarnieri MT, Vasil AI, Vasil ML, Mant CT, Hodges RS. Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrobial Agents and Chemotherapy. 51: 1398-406. PMID 17158938 DOI: 10.1128/AAC.00925-06  1
2007 Chen Y, Mant CT, Hodges RS. Preparative reversed-phase high-performance liquid chromatography collection efficiency for an antimicrobial peptide on columns of varying diameters (1mm to 9.4mm I.D.). Journal of Chromatography. A. 1140: 112-20. PMID 17156789 DOI: 10.1016/j.chroma.2006.11.052  1
2006 Howard MW, Tripet B, Jobling MG, Holmes RK, Holmes KV, Hodges RS. Dissection of the fusion machine of SARS-coronavirus. Advances in Experimental Medicine and Biology. 581: 319-22. PMID 17037552 DOI: 10.1007/978-0-387-33012-9_56  1
2006 Mills JB, Mant CT, Hodges RS. One-step purification of a recombinant protein from a whole cell extract by reversed-phase high-performance liquid chromatography Journal of Chromatography A. 1133: 248-253. PMID 16945380 DOI: 10.1016/j.chroma.2006.08.042  1
2006 Yan Z, Tripet B, Hodges RS. Biophysical characterization of HRC peptide analogs interaction with heptad repeat regions of the SARS-coronavirus Spike fusion protein core. Journal of Structural Biology. 155: 162-75. PMID 16765058 DOI: 10.1016/j.jsb.2006.03.024  1
2006 Kovacs JM, Mant CT, Kwok SC, Osguthorpe DJ, Hodges RS. Quantitation of the nearest-neighbour effects of amino acid side-chains that restrict conformational freedom of the polypeptide chain using reversed-phase liquid chromatography of synthetic model peptides with L- and D-amino acid substitutions. Journal of Chromatography. A. 1123: 212-24. PMID 16712857 DOI: 10.1016/j.chroma.2006.04.092  1
2006 Tripet B, Kao DJ, Jeffers SA, Holmes KV, Hodges RS. Template-based coiled-coil antigens elicit neutralizing antibodies to the SARS-coronavirus. Journal of Structural Biology. 155: 176-94. PMID 16697221 DOI: 10.1016/j.jsb.2006.03.019  1
2006 Helmke SM, Lu SM, Harmon M, Glasford JW, Larsen TD, Kwok SC, Hodges RS, Perryman MB. Myotonic dystrophy protein kinase monoclonal antibody generation from a coiled-coil template. Journal of Molecular Recognition : Jmr. 19: 215-26. PMID 16680721 DOI: 10.1002/jmr.769  1
2006 Popa TV, Mant CT, Hodges RS. Ion-interaction-capillary zone electrophoresis of cationic proteomic peptide standards. Journal of Chromatography. A. 1111: 192-9. PMID 16569578 DOI: 10.1016/j.chroma.2005.07.015  1
2006 Chen Y, Vasil AI, Rehaume L, Mant CT, Burns JL, Vasil ML, Hancock RE, Hodges RS. Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides. Chemical Biology & Drug Design. 67: 162-73. PMID 16492164 DOI: 10.1111/j.1747-0285.2006.00349.x  1
2006 Giltner CL, van Schaik EJ, Audette GF, Kao D, Hodges RS, Hassett DJ, Irvin RT. The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Molecular Microbiology. 59: 1083-96. PMID 16430686 DOI: 10.1111/j.1365-2958.2005.05002.x  1
2006 Kovacs JM, Mant CT, Hodges RS. Determination of intrinsic hydrophilicity/hydrophobicity of amino acid side chains in peptides in the absence of nearest-neighbor or conformational effects. Biopolymers. 84: 283-97. PMID 16315143 DOI: 10.1002/bip.20417  1
2005 Wardell SE, Kwok SC, Sherman L, Hodges RS, Edwards DP. Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. Molecular and Cellular Biology. 25: 8792-808. PMID 16199860 DOI: 10.1128/MCB.25.20.8792-8808.2005  1
2005 Barany G, Hodges RS, Sawyer TK. Hail to the editor-in-chief: an appreciation of Victor J. Hruby, outstanding scientist-mentor-leader in peptide research. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 515-7. PMID 15885110 DOI: 10.1111/j.1399-3011.2005.00260.x  0.56
2005 Martin SL, Cruceanu M, Branciforte D, Wai-Lun Li P, Kwok SC, Hodges RS, Williams MC. LINE-1 retrotransposition requires the nucleic acid chaperone activity of the ORF1 protein. Journal of Molecular Biology. 348: 549-61. PMID 15826653 DOI: 10.1016/j.jmb.2005.03.003  1
2005 Chen Y, Mant CT, Farmer SW, Hancock RE, Vasil ML, Hodges RS. Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. The Journal of Biological Chemistry. 280: 12316-29. PMID 15677462 DOI: 10.1074/jbc.M413406200  1
2005 Prenner EJ, Kiricsi M, Jelokhani-Niaraki M, Lewis RN, Hodges RS, McElhaney RN. Structure-activity relationships of diastereomeric lysine ring size analogs of the antimicrobial peptide gramicidin S: mechanism of action and discrimination between bacterial and animal cell membranes. The Journal of Biological Chemistry. 280: 2002-11. PMID 15542606 DOI: 10.1074/jbc.M406509200  1
2004 Lindhout DA, Litowski JR, Mercier P, Hodges RS, Sykes BD. NMR solution structure of a highly stable de novo heterodimeric coiled-coil. Biopolymers. 75: 367-75. PMID 15457434 DOI: 10.1002/bip.20150  1
2004 Cachia PJ, Kao DJ, Hodges RS. Synthetic peptide vaccine development: measurement of polyclonal antibody affinity and cross-reactivity using a new peptide capture and release system for surface plasmon resonance spectroscopy. Journal of Molecular Recognition : Jmr. 17: 540-57. PMID 15386623 DOI: 10.1002/jmr.682  1
2004 Kwok SC, Hodges RS. Effect of chain length on coiled-coil stability: decreasing stability with increasing chain length. Biopolymers. 76: 378-90. PMID 15372485 DOI: 10.1002/bip.20141  1
2004 Popa TV, Mant CT, Chen Y, Hodges RS. Capillary zone electrophoresis of alpha-helical diastereomeric peptide pairs with anionic ion-pairing reagents. Journal of Chromatography. A. 1043: 113-22. PMID 15317419 DOI: 10.1016/j.chroma.2004.04.029  1
2004 Popa TV, Mant CT, Hodges RS. Capillary electrophoresis of cationic random coil peptide standards: effect of anionic ion-pairing reagents and comparison with reversed-phase chromatography. Electrophoresis. 25: 1219-29. PMID 15174041 DOI: 10.1002/elps.200305889  1
2004 Houliston RS, Hodges RS, Sharom FJ, Davis JH. Characterization of the proto-oncogenic and mutant forms of the transmembrane region of Neu in micelles. The Journal of Biological Chemistry. 279: 24073-80. PMID 15051716 DOI: 10.1074/jbc.M401919200  1
2004 Kwok SC, Hodges RS. Stabilizing and destabilizing clusters in the hydrophobic core of long two-stranded alpha-helical coiled-coils. The Journal of Biological Chemistry. 279: 21576-88. PMID 15020585 DOI: 10.1074/jbc.M401074200  1
2004 Lee DL, Powers JP, Pflegerl K, Vasil ML, Hancock RE, Hodges RS. Effects of single D-amino acid substitutions on disruption of beta-sheet structure and hydrophobicity in cyclic 14-residue antimicrobial peptide analogs related to gramicidin S. The Journal of Peptide Research : Official Journal of the American Peptide Society. 63: 69-84. PMID 15009528  1
2004 Tripet B, Howard MW, Jobling M, Holmes RK, Holmes KV, Hodges RS. Structural characterization of the SARS-coronavirus spike S fusion protein core. The Journal of Biological Chemistry. 279: 20836-49. PMID 14996844 DOI: 10.1074/jbc.M400759200  1
2004 Lu SM, Hodges RS. Defining the minimum size of a hydrophobic cluster in two-stranded alpha-helical coiled-coils: effects on protein stability. Protein Science : a Publication of the Protein Society. 13: 714-26. PMID 14978309 DOI: 10.1110/ps.03443204  1
2004 Popa TV, Mant CT, Hodges RS. Capillary electrophoresis of amphipathic alpha-helical peptide diastereomers. Electrophoresis. 25: 94-107. PMID 14730573 DOI: 10.1002/elps.200305654  1
2003 Hillar A, Tripet B, Zoetewey D, Wood JM, Hodges RS, Boggs JM. Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus. Biochemistry. 42: 15170-8. PMID 14690427 DOI: 10.1021/bi035122t  1
2003 Popa TV, Mant CT, Hodges RS. Capillary electrophoresis of synthetic peptide standards varying in charge and hydrophobicity. Electrophoresis. 24: 4197-208. PMID 14679567 DOI: 10.1002/elps.200305576  1
2003 Zoetewey DL, Tripet BP, Kutateladze TG, Overduin MJ, Wood JM, Hodges RS. Solution structure of the C-terminal antiparallel coiled-coil domain from Escherichia coli osmosensor ProP. Journal of Molecular Biology. 334: 1063-76. PMID 14643666 DOI: 10.1016/j.jmb.2003.10.020  1
2003 Chen Y, Mant CT, Hodges RS. Temperature selectivity effects in reversed-phase liquid chromatography due to conformation differences between helical and non-helical peptides. Journal of Chromatography. A. 1010: 45-61. PMID 14503815  1
2003 Hartmann E, Chen Y, Mant CT, Jungbauer A, Hodges RS. Comparison of reversed-phase liquid chromatography and hydrophilic interaction/cation-exchange chromatography for the separation of amphipathic alpha-helical peptides with L- and D-amino acid substitutions in the hydrophilic face. Journal of Chromatography. A. 1009: 61-71. PMID 13677645  1
2003 Mant CT, Tripet B, Hodges RS. Temperature profiling of polypeptides in reversed-phase liquid chromatography. II. Monitoring of folding and stability of two-stranded alpha-helical coiled-coils. Journal of Chromatography. A. 1009: 45-59. PMID 13677644  1
2003 Mant CT, Chen Y, Hodges RS. Temperature profiling of polypeptides in reversed-phase liquid chromatography. I. Monitoring of dimerization and unfolding of amphipathic alpha-helical peptides. Journal of Chromatography. A. 1009: 29-43. PMID 13677643  1
2003 Kwok SC, Hodges RS. Clustering of large hydrophobes in the hydrophobic core of two-stranded alpha-helical coiled-coils controls protein folding and stability. The Journal of Biological Chemistry. 278: 35248-54. PMID 12842878 DOI: 10.1074/jbc.M305306200  1
2003 Lee DL, Ivaninskii S, Burkhard P, Hodges RS. Unique stabilizing interactions identified in the two-stranded alpha-helical coiled-coil: crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide. Protein Science : a Publication of the Protein Society. 12: 1395-405. PMID 12824486 DOI: 10.1110/ps.0241403  1
2003 Cachia PJ, Hodges RS. Synthetic peptide vaccine and antibody therapeutic development: prevention and treatment of Pseudomonas aeruginosa. Biopolymers. 71: 141-68. PMID 12767116 DOI: 10.1002/bip.10395  1
2003 Lee DL, Hodges RS. Structure-activity relationships of de novo designed cyclic antimicrobial peptides based on gramicidin S. Biopolymers. 71: 28-48. PMID 12712499 DOI: 10.1002/bip.10374  1
2003 Lee DL, Mant CT, Hodges RS. A novel method to measure self-association of small amphipathic molecules: temperature profiling in reversed-phase chromatography. The Journal of Biological Chemistry. 278: 22918-27. PMID 12686558 DOI: 10.1074/jbc.M301777200  1
2003 De Crescenzo G, Litowski JR, Hodges RS, O'Connor-McCourt MD. Real-time monitoring of the interactions of two-stranded de novo designed coiled-coils: effect of chain length on the kinetic and thermodynamic constants of binding. Biochemistry. 42: 1754-63. PMID 12578390 DOI: 10.1021/bi0268450  1
2003 Houliston RS, Hodges RS, Sharom FJ, Davis JH. Comparison of proto-oncogenic and mutant forms of the transmembrane region of the Neu receptor in TFE. Febs Letters. 535: 39-43. PMID 12560075 DOI: 10.1016/S0014-5793(02)03852-8  1
2003 Tripet B, De Crescenzo G, Grothe S, O'Connor-McCourt M, Hodges RS. Kinetic analysis of the interactions between troponin C (TnC) and troponin I (TnI) binding peptides: evidence for separate binding sites for the 'structural' N-terminus and the 'regulatory' C-terminus of TnI on TnC. Journal of Molecular Recognition : Jmr. 16: 37-53. PMID 12557238 DOI: 10.1002/jmr.606  1
2002 Kiricsi M, Prenner EJ, Jelokhani-Niaraki M, Lewis RN, Hodges RS, McElhaney RN. The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B. European Journal of Biochemistry / Febs. 269: 5911-20. PMID 12444980  1
2002 Mant CT, Hodges RS. Preparative reversed-phase liquid chromatography of proteins from rabbit skeletal troponin, a multi-protein complex. Journal of Chromatography. A. 972: 101-14. PMID 12395950  1
2002 Mehok AR, Mant CT, Gera L, Stewart J, Hodges RS. Preparative reversed-phase liquid chromatography of peptides. Isocratic two-step elution system for high loads on analytical columns. Journal of Chromatography. A. 972: 87-99. PMID 12395949  1
2002 Mant CT, Hodges RS. Reversed-phase liquid chromatography as a tool in the determination of the hydrophilicity/hydrophobicity of amino acid side-chains at a ligand-receptor interface in the presence of different aqueous environments. II. Effect of varying peptide ligand hydrophobicity. Journal of Chromatography. A. 972: 61-75. PMID 12395947  1
2002 Mant CT, Hodges RS. Reversed-phase liquid chromatography as a tool in the determination of the hydrophilicity/hydrophobicity of amino acid side-chains at a ligand-receptor interface in the presence of different aqueous environments. I. Effect of varying receptor hydrophobicity. Journal of Chromatography. A. 972: 45-60. PMID 12395946  1
2002 Tripet B, De Crescenzo G, Grothe S, O'Connor-McCourt M, Hodges RS. Kinetic analysis of the interactions between troponin C and the C-terminal troponin I regulatory region and validation of a new peptide delivery/capture system used for surface plasmon resonance. Journal of Molecular Biology. 323: 345-62. PMID 12381325 DOI: 10.1016/S0022-2836(02)00883-5  1
2002 Litowski JR, Hodges RS. Designing heterodimeric two-stranded alpha-helical coiled-coils. Effects of hydrophobicity and alpha-helical propensity on protein folding, stability, and specificity. The Journal of Biological Chemistry. 277: 37272-9. PMID 12138097 DOI: 10.1074/jbc.M204257200  1
2002 Tripet B, Hodges RS. Helix capping interactions stabilize the N-terminus of the kinesin neck coiled-coil. Journal of Structural Biology. 137: 220-35. PMID 12064948 DOI: 10.1006/jsbi.2002.4475  1
2002 Chana M, Tripet BP, Mant CT, Hodges RS. The role of unstructured highly charged regions on the stability and specificity of dimerization of two-stranded alpha-helical coiled-coils: analysis of the neck-hinge region of the kinesin-like motor protein Kif3A. Journal of Structural Biology. 137: 206-19. PMID 12064947 DOI: 10.1006/jsbi.2002.4446  1
2002 Kwok SC, Mant CT, Hodges RS. Importance of secondary structural specificity determinants in protein folding: insertion of a native beta-sheet sequence into an alpha-helical coiled-coil. Protein Science : a Publication of the Protein Society. 11: 1519-31. PMID 12021450 DOI: 10.1110/ps.4170102  1
2002 Lu SM, Hodges RS. A de novo designed template for generating conformation-specific antibodies that recognize alpha-helices in proteins. The Journal of Biological Chemistry. 277: 23515-24. PMID 11971904 DOI: 10.1074/jbc.M201981200  1
2002 Kondejewski LH, Lee DL, Jelokhani-Niaraki M, Farmer SW, Hancock RE, Hodges RS. Optimization of microbial specificity in cyclic peptides by modulation of hydrophobicity within a defined structural framework. The Journal of Biological Chemistry. 277: 67-74. PMID 11682479 DOI: 10.1074/jbc.M107825200  1
2001 Litowski JR, Hodges RS. Designing heterodimeric two-stranded alpha-helical coiled-coils: the effect of chain length on protein folding, stability and specificity. The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 477-92. PMID 12005418  1
2001 Ngai SM, Pearlstone JR, Smillie LB, Hodges RS. Characterization of the biologically important interaction between troponin C and the N-terminal region of troponin I. Journal of Cellular Biochemistry. 83: 99-110. PMID 11500958 DOI: 10.1002/jcb.1212  1
2001 Ngai SM, Pearlstone JR, Farah CS, Reinach FC, Smillie LB, Hodges RS. Structural and functional studies on Troponin I and Troponin C interactions. Journal of Cellular Biochemistry. 83: 33-46. PMID 11500952 DOI: 10.1002/jcb.1204  1
2001 Lee DL, Lavigne P, Hodges RS. Are trigger sequences essential in the folding of two-stranded alpha-helical coiled-coils? Journal of Molecular Biology. 306: 539-53. PMID 11178912 DOI: 10.1006/jmbi.2000.4351  1
1999 Litowski JR, Semchuk PD, Mant CT, Hodges RS. Hydrophilic interaction/cation-exchange chromatography for the purification of synthetic peptides from closely related impurities: serine side-chain acetylated peptides. The Journal of Peptide Research : Official Journal of the American Peptide Society. 54: 1-11. PMID 10448964  1
1999 Okamoto PM, Tripet B, Litowski J, Hodges RS, Vallee RB. Multiple distinct coiled-coils are involved in dynamin self-assembly. The Journal of Biological Chemistry. 274: 10277-86. PMID 10187814 DOI: 10.1074/jbc.274.15.10277  1
1998 Chao H, Bautista DL, Litowski J, Irvin RT, Hodges RS. Use of a heterodimeric coiled-coil system for biosensor application and affinity purification Journal of Chromatography B: Biomedical Applications. 715: 307-329. PMID 9792518 DOI: 10.1016/S0378-4347(98)00172-8  1
1998 Mant CT, Litowski JR, Hodges RS. Hydrophilic interaction/cation-exchange chromatography for separation of amphipathic alpha-helical peptides. Journal of Chromatography. A. 816: 65-78. PMID 9741101  1
1998 Kwok SC, Tripet B, Man JH, Chana MS, Lavigne P, Mant CT, Hodges RS. Structural cassette mutagenesis in a de novo designed protein: proof of a novel concept for examining protein folding and stability. Biopolymers. 47: 101-23. PMID 9692331 DOI: 10.1002/(SICI)1097-0282(1998)47:1<101::AID-BIP11>3.0.CO;2-L  1
1998 Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Circulation Research. 82: 261-71. PMID 9468197  1
1997 Tripet B, Van Eyk JE, Hodges RS. Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction. Journal of Molecular Biology. 271: 728-50. PMID 9299323 DOI: 10.1006/jmbi.1997.1200  1
1997 Van Eyk JE, Thomas LT, Tripet B, Wiesner RJ, Pearlstone JR, Farah CS, Reinach FC, Hodges RS. Distinct regions of troponin I regulate Ca2+-dependent activation and Ca2+ sensitivity of the acto-S1-TM ATPase activity of the thin filament. The Journal of Biological Chemistry. 272: 10529-37. PMID 9099697  1
1995 Van Eyk JE, Caday-Malcolm RA, Yu L, Irvin RT, Hodges RS. Anti-peptide monoclonal antibody imaging of a common binding domain involved in muscle regulation Protein Science. 4: 781-790. PMID 7613476  1
1993 Van Eyk JE, Strauss JD, Hodges RS, Rüegg JC. A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. Febs Letters. 323: 223-8. PMID 8500614 DOI: 10.1016/0014-5793(93)81344-Y  1
1992 Campbell AP, Van Eyk JE, Hodges RS, Sykes BD. Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C. Biochimica Et Biophysica Acta. 1160: 35-54. PMID 1420332  1
1992 Sönnichsen FD, Van Eyk JE, Hodges RS, Sykes BD. Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide. Biochemistry. 31: 8790-8. PMID 1390666  1
1991 Van Eyk JE, Kay CM, Hodges RS. A comparative study of the interactions of synthetic peptides of the skeletal and cardiac troponin I inhibitory region with skeletal and cardiac troponin C. Biochemistry. 30: 9974-81. PMID 1911788  1
1991 Van Eyk JE, Hodges RS. A synthetic peptide of the N-terminus of actin interacts with myosin. Biochemistry. 30: 11676-82. PMID 1836353  1
1988 Van Eyk JE, Hodges RS. The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin. The Journal of Biological Chemistry. 263: 1726-32. PMID 3338991  1
1987 Van Eyk JE, Hodges RS. Calmodulin and troponin C: affinity chromatographic study of divalent cation requirements for troponin I inhibitory peptide (residues 104-115), mastoparan and fluphenazine binding. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 982-8. PMID 3442631  1
1978 Sodek J, Hodges RS, Smillie LB. Amino acid sequence of rabbit skeletal muscle alpha-tropomyosin. The COOH-terminal half (residues 142 to 284). The Journal of Biological Chemistry. 253: 1129-36. PMID 624723  1
1976 Mitchell AR, Erickson BW, Ryabtsev MN, Hodges RS, Merrifield RB. Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis. Journal of the American Chemical Society. 98: 7357-62. PMID 10319  1
1975 Hodges RS, Merrifield RB. Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method. Analytical Biochemistry. 65: 241-72. PMID 1130679  1
1975 Hodges RS, Merrifield RB. The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs. The Journal of Biological Chemistry. 250: 1231-41. PMID 1112802  1
1974 Hodges RS, Merrifield RB. Synthesis of O-methyl-L-serine and Nalpha-tert-butyloxycarbonyl-O-methyl-L-serine. The Journal of Organic Chemistry. 39: 1870-2. PMID 4854587  1
1974 Hodges RS, Merrifield RB. Synthetic study of the effect of tyrosine at position 120 of ribonuclease. International Journal of Peptide and Protein Research. 6: 397-405. PMID 4455636  1
1973 Hodges RS, Smillie LB. Cyanogen bromide fragments of rabbit skeletal tropomyosin. Canadian Journal of Biochemistry. 51: 56-70. PMID 4689095  1
1972 Hodges RS, Smillie LB. The histidine and methionine sequences of rabbit skeletal tropomyosin. Canadian Journal of Biochemistry. 50: 312-29. PMID 5020793  1
1972 Hodges RS, Sodek J, Smillie LB. The cyanogen bromide fragments of rabbit skeletal-muscle tropomyosin. The Biochemical Journal. 128: 102P. PMID 4634818  1
1972 Hodges RS, Smillie LB. Cysteine sequences of rabbit skeletal tropomyosin. Canadian Journal of Biochemistry. 50: 330-43. PMID 4553610  1
1972 Sodek J, Hodges RS, Smillie LB, Jurasek L. Amino-acid sequence of rabbit skeletal tropomyosin and its coiled-coil structure. Proceedings of the National Academy of Sciences of the United States of America. 69: 3800-4. PMID 4509342  1
1970 Hodges RS, Smillie LB. Chemical evidence for chain heterogeneity in rabbit muscle tropomyosin. Biochemical and Biophysical Research Communications. 41: 987-94. PMID 5529281  1
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