Year |
Citation |
Score |
2023 |
Liu X, Reinbold R, Liu S, Herold RA, Rabe P, Duclos S, Yadav RB, Abboud MI, Thieffine S, Armstrong FA, Brewitz L, Schofield CJ. Natural and Synthetic 2-Oxogluturate Derivatives are Substrates for Oncogenic Variants of Human Isocitrate Dehydrogenase 1 and 2. The Journal of Biological Chemistry. 102873. PMID 36621625 DOI: 10.1016/j.jbc.2023.102873 |
0.338 |
|
2021 |
Vogt CD, Bart AG, Yadav R, Scott EE, Aubé J. Effects of fluorine substitution on substrate conversion by cytochromes P450 17A1 and 21A2. Organic & Biomolecular Chemistry. 19: 7664-7669. PMID 34524336 DOI: 10.1039/d1ob01178b |
0.722 |
|
2020 |
Wróbel TM, Rogova O, Andersen KL, Yadav R, Brixius-Anderko S, Scott EE, Olsen L, Jørgensen FS, Björkling F. Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents. International Journal of Molecular Sciences. 21. PMID 32660148 DOI: 10.3390/Ijms21144868 |
0.688 |
|
2020 |
van Rooyen D, Yadav R, Scott EE, Swart AC. CYP17A1 exhibits 17α-hydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway. The Journal of Steroid Biochemistry and Molecular Biology. 105614. PMID 32007561 DOI: 10.1016/J.Jsbmb.2020.105614 |
0.549 |
|
2018 |
Yadav R, Scott EE. Endogenous insertion of non-native metalloporphyrins into human membrane cytochrome P450 enzymes. The Journal of Biological Chemistry. PMID 30217815 DOI: 10.1074/Jbc.Ra118.005417 |
0.619 |
|
2018 |
Fehl C, Vogt CD, Yadav R, Li K, Scott EE, Aubé J. Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2. Journal of Medicinal Chemistry. PMID 29792703 DOI: 10.1021/Acs.Jmedchem.8B00419 |
0.678 |
|
2017 |
Li A, Yadav R, White JK, Herroon MK, Callahan BP, Podgorski I, Turro C, Scott EE, Kodanko JJ. Illuminating cytochrome P450 binding: Ru(ii)-caged inhibitors of CYP17A1. Chemical Communications (Cambridge, England). PMID 28304025 DOI: 10.1039/C7Cc01459G |
0.615 |
|
2016 |
Yadav R, Petrunak EM, Estrada DF, Scott EE. Structural insights into the function of steroidogenic cytochrome P450 17A1. Molecular and Cellular Endocrinology. PMID 27566228 DOI: 10.1016/J.Mce.2016.08.035 |
0.665 |
|
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