Kimberly Ann Reynolds - Publications

University of Texas Southwestern Medical Center, Dallas, TX, United States 
Systems biology, synthetic biology, computational biology, molecular evolution

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Thompson S, Zhang Y, Ingle C, Reynolds K, Kortemme T. Altered expression of a quality control protease in reshapes the in vivo mutational landscape of a model enzyme. Elife. 9. PMID 32701056 DOI: 10.7554/Elife.53476  0.403
2019 McCormick JW, Pincus D, Resnekov O, Reynolds KA. Strategies for Engineering and Rewiring Kinase Regulation. Trends in Biochemical Sciences. PMID 31866305 DOI: 10.1016/J.Tibs.2019.11.005  0.336
2019 Tamer YT, Gaszek IK, Abdizadeh H, Batur TA, Reynolds K, Atilgan AR, Atilgan C, Toprak E. High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection. Molecular Biology and Evolution. PMID 30982891 DOI: 10.1093/Molbev/Msz086  0.397
2018 Pincus D, Pandey JP, Feder ZA, Creixell P, Resnekov O, Reynolds KA. Engineering allosteric regulation in protein kinases. Science Signaling. 11. PMID 30401787 DOI: 10.1126/Scisignal.Aar3250  0.368
2018 Rosensweig C, Reynolds KA, Gao P, Laothamatas I, Shan Y, Ranganathan R, Takahashi JS, Green CB. An evolutionary hotspot defines functional differences between CRYPTOCHROMES. Nature Communications. 9: 1138. PMID 29556064 DOI: 10.1038/S41467-018-03503-6  0.565
2017 Narayanan C, Gagné D, Reynolds KA, Doucet N. Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily. Scientific Reports. 7: 3207. PMID 28600532 DOI: 10.1038/S41598-017-03298-4  0.339
2017 Pincus D, Resnekov O, Reynolds K. An evolution-based strategy for engineering allosteric regulation. Physical Biology. PMID 28266924 DOI: 10.1088/1478-3975/Aa64A4  0.432
2016 Rivoire O, Reynolds KA, Ranganathan R. Evolution-Based Functional Decomposition of Proteins. Plos Computational Biology. 12: e1004817. PMID 27254668 DOI: 10.1371/Journal.Pcbi.1004817  0.634
2015 Reynolds KA. A new test of computational protein design: predicting posttranslational modification specificity for the enzyme SMYD2. Structure (London, England : 1993). 23: 11-2. PMID 25565104 DOI: 10.1016/J.Str.2014.12.004  0.429
2013 Reynolds KA, Russ WP, Socolich M, Ranganathan R. Evolution-based design of proteins. Methods in Enzymology. 523: 213-35. PMID 23422432 DOI: 10.1016/B978-0-12-394292-0.00010-2  0.679
2011 Reynolds KA, McLaughlin RN, Ranganathan R. Hot spots for allosteric regulation on protein surfaces. Cell. 147: 1564-75. PMID 22196731 DOI: 10.1016/J.Cell.2011.10.049  0.58
2011 Hanes MS, Reynolds KA, McNamara C, Ghosh P, Bonomo RA, Kirsch JF, Handel TM. Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins. 79: 1267-76. PMID 21294157 DOI: 10.1002/Prot.22961  0.697
2009 Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of Molecular Recognition : Jmr. 22: 307-18. PMID 19353579 DOI: 10.1002/Jmr.949  0.357
2009 Reynolds KA, Katritch V, Abagyan R. Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators. Journal of Computer-Aided Molecular Design. 23: 273-88. PMID 19148767 DOI: 10.1007/S10822-008-9257-9  0.338
2008 Reynolds KA, Hanes MS, Thomson JM, Antczak AJ, Berger JM, Bonomo RA, Kirsch JF, Handel TM. Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface. Journal of Molecular Biology. 382: 1265-75. PMID 18775544 DOI: 10.1016/J.Jmb.2008.05.051  0.713
2007 Chowdry AB, Reynolds KA, Hanes MS, Voorhies M, Pokala N, Handel TM. An object-oriented library for computational protein design. Journal of Computational Chemistry. 28: 2378-88. PMID 17471459 DOI: 10.1002/Jcc.20727  0.56
2006 Reynolds KA, Thomson JM, Corbett KD, Bethel CR, Berger JM, Kirsch JF, Bonomo RA, Handel TM. Structural and computational characterization of the SHV-1 beta-lactamase-beta-lactamase inhibitor protein interface. The Journal of Biological Chemistry. 281: 26745-53. PMID 16809340 DOI: 10.1074/Jbc.M603878200  0.715
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