Craig B. Thompson - Publications

Affiliations: 
Cancer Biology Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
Website:
http://www.mskcc.org/research/lab/craig-thompson

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, ... ... Thompson CB, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation. PMID 30222137 DOI: 10.1172/JCI124920  0.56
2018 Redelman-Sidi G, Binyamin A, Gaeta I, Palm W, Thompson CB, Romesser PB, Lowe SW, Bagul M, Doench JG, Root DE, Glickman MS. The Canonical Wnt Pathway Drives Macropinocytosis in Cancer. Cancer Research. PMID 29871936 DOI: 10.1158/0008-5472.CAN-17-3199  1
2018 Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB. Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nature Cell Biology. PMID 29662175 DOI: 10.1038/s41556-018-0086-3  0.36
2018 McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, ... ... Thompson CB, et al. JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation. PMID 29355841 DOI: 10.1172/JCI94516  0.56
2018 Pavlova NN, Hui S, Ghergurovich JM, Fan J, Intlekofer AM, White RM, Rabinowitz JD, Thompson CB, Zhang J. As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid. Cell Metabolism. PMID 29337136 DOI: 10.1016/j.cmet.2017.12.006  0.48
2017 Palm W, Araki J, King B, DeMatteo RG, Thompson CB. Critical role for PI3-kinase in regulating the use of proteins as an amino acid source. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973876 DOI: 10.1073/pnas.1712726114  1
2017 Palm W, Thompson CB. Nutrient acquisition strategies of mammalian cells. Nature. 546: 234-242. PMID 28593971 DOI: 10.1038/nature22379  1
2017 Zhang J, Pavlova NN, Thompson CB. Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine. The Embo Journal. PMID 28420743 DOI: 10.15252/embj.201696151  0.48
2017 Thompson CB, Palm W. Reexamining How Cancer Cells Exploit the Body's Metabolic Resources. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28396524 DOI: 10.1101/sqb.2016.81.030734  1
2016 Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, ... ... Thompson CB, et al. Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Science Translational Medicine. 8: 366ra161. PMID 27881822 DOI: 10.1126/scitranslmed.aah6904  0.52
2016 Krishna S, Palm W, Lee Y, Yang W, Bandyopadhyay U, Xu H, Florey O, Thompson CB, Overholtzer M. PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment. Developmental Cell. 38: 536-547. PMID 27623384 DOI: 10.1016/j.devcel.2016.08.001  1
2016 Chio II, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, ... ... Thompson CB, et al. NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell. PMID 27477511 DOI: 10.1016/j.cell.2016.06.056  1
2016 Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, ... ... Thompson CB, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science (New York, N.Y.). 352: 844-9. PMID 27174990 DOI: 10.1126/science.aac7272  0.92
2016 Pavlova NN, Thompson CB. The Emerging Hallmarks of Cancer Metabolism. Cell Metabolism. 23: 27-47. PMID 26771115 DOI: 10.1016/j.cmet.2015.12.006  0.92
2015 Ye J, Palm W, Peng M, King B, Lindsten T, Li MO, Koumenis C, Thompson CB. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. Genes & Development. PMID 26543160 DOI: 10.1101/gad.269324.115  0.92
2015 Intlekofer AM, Dematteo RG, Venneti S, Finley LW, Lu C, Judkins AR, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Thompson CB. Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metabolism. PMID 26212717 DOI: 10.1016/j.cmet.2015.06.023  0.92
2015 Palm W, Park Y, Wright K, Pavlova NN, Tuveson DA, Thompson CB. The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1. Cell. 162: 259-70. PMID 26144316 DOI: 10.1016/j.cell.2015.06.017  0.92
2015 Saleiro D, Mehrotra S, Kroczynska B, Beauchamp EM, Lisowski P, Majchrzak-Kita B, Bhagat TD, Stein BL, McMahon B, Altman JK, Kosciuczuk EM, Baker DP, Jie C, Jafari N, Thompson CB, et al. Central role of ULK1 in type I interferon signaling. Cell Reports. 11: 605-17. PMID 25892232 DOI: 10.1016/j.celrep.2015.03.056  0.92
2015 Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, ... ... Thompson CB, et al. Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo. Science Translational Medicine. 7: 274ra17. PMID 25673762 DOI: 10.1126/scitranslmed.aaa1009  0.92
2015 Jiang X, Overholtzer M, Thompson CB. Autophagy in cellular metabolism and cancer. The Journal of Clinical Investigation. 125: 47-54. PMID 25654550 DOI: 10.1172/JCI73942  0.92
2015 Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, Thompson CB, Rabinowitz JD. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Research. 75: 544-53. PMID 25644265 DOI: 10.1158/0008-5472.CAN-14-2211  0.56
2015 La Rocca G, Olejniczak SH, González AJ, Briskin D, Vidigal JA, Spraggon L, DeMatteo RG, Radler MR, Lindsten T, Ventura A, Tuschl T, Leslie CS, Thompson CB. In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. Proceedings of the National Academy of Sciences of the United States of America. 112: 767-72. PMID 25568082 DOI: 10.1073/pnas.1424217112  0.52
2015 Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature. 518: 413-6. PMID 25487152 DOI: 10.1038/nature13981  0.92
2015 Neill US, Thompson CB, Gibson DS. Assessing research productivity Scientist. 29.  0.92
2014 Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, ... ... Thompson CB, et al. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Reports. 9: 1841-55. PMID 25482556 DOI: 10.1016/j.celrep.2014.11.004  0.92
2014 Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, ... ... Thompson CB, et al. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Reports. 9: 1841-55. PMID 25482556 DOI: 10.1016/j.celrep.2014.11.004  0.92
2014 Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/j.molcel.2014.08.018  0.92
2014 Zhang J, Fan J, Venneti S, Cross JR, Takagi T, Bhinder B, Djaballah H, Kanai M, Cheng EH, Judkins AR, Pawel B, Baggs J, Cherry S, Rabinowitz JD, Thompson CB. Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. Molecular Cell. 56: 205-18. PMID 25242145 DOI: 10.1016/j.molcel.2014.08.018  0.92
2014 Venneti S, Santi M, Felicella MM, Yarilin D, Phillips JJ, Sullivan LM, Martinez D, Perry A, Lewis PW, Thompson CB, Judkins AR. A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas. Acta Neuropathologica. 128: 743-53. PMID 25200322 DOI: 10.1007/s00401-014-1338-3  0.92
2014 Venneti S, Santi M, Felicella MM, Yarilin D, Phillips JJ, Sullivan LM, Martinez D, Perry A, Lewis PW, Thompson CB, Judkins AR. A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas. Acta Neuropathologica. 128: 743-53. PMID 25200322 DOI: 10.1007/s00401-014-1338-3  0.92
2014 Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.CD-14-0250  0.92
2014 Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB. Serine catabolism regulates mitochondrial redox control during hypoxia. Cancer Discovery. 4: 1406-17. PMID 25186948 DOI: 10.1158/2159-8290.CD-14-0250  0.92
2014 Kultti A, Zhao C, Singha NC, Zimmerman S, Osgood RJ, Symons R, Jiang P, Li X, Thompson CB, Infante JR, Jacobetz MA, Tuveson DA, Frost GI, Shepard HM, Huang Z. Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment. Biomed Research International. 2014: 817613. PMID 25147816 DOI: 10.1155/2014/817613  0.48
2014 Kultti A, Zhao C, Singha NC, Zimmerman S, Osgood RJ, Symons R, Jiang P, Li X, Thompson CB, Infante JR, Jacobetz MA, Tuveson DA, Frost GI, Shepard HM, Huang Z. Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment. Biomed Research International. 2014: 817613. PMID 25147816 DOI: 10.1155/2014/817613  0.48
2014 Thompson CB. Wnt meets Warburg: Another piece in the puzzle? Embo Journal. 33: 1420-1422. PMID 24843042 DOI: 10.15252/embj.201488785  0.92
2014 Shi Y, Wang J, Chandarlapaty S, Cross J, Thompson C, Rosen N, Jiang X. PTEN is a protein tyrosine phosphatase for IRS1 Nature Structural and Molecular Biology. 21: 522-527. PMID 24814346 DOI: 10.1038/nsmb.2828  0.92
2014 Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Quantitative flux analysis reveals folate-dependent NADPH production. Nature. 510: 298-302. PMID 24805240 DOI: 10.1038/nature13236  0.92
2014 Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Quantitative flux analysis reveals folate-dependent NADPH production. Nature. 510: 298-302. PMID 24805240 DOI: 10.1038/nature13236  0.92
2014 Cheong H, Wu J, Gonzales LK, Guttentag SH, Thompson CB, Lindsten T. Analysis of a lung defect in autophagy-deficient mouse strains Autophagy. 10: 45-56. PMID 24275123 DOI: 10.4161/auto.26505  0.92
2014 Fan J, Ye J, Kamphorst JJ, Shlomi T, Thompson CB, Rabinowitz JD. Corrigendum: Quantitative flux analysis reveals folate-dependent NADPH production Nature. 513: 574. DOI: 10.1038/nature13675  0.92
2014 Mendelsohn J, Gray JW, Howley PM, Israel MA, Thompson CB. Preface The Molecular Basis of Cancer: Fourth Edition. xix. DOI: 10.1016/B978-1-4557-4066-6.05001-0  0.92
2014 Finley LWS, Thompson CB. The Metabolism of Cell Growth and Proliferation The Molecular Basis of Cancer: Fourth Edition. 191-208.e2. DOI: 10.1016/B978-1-4557-4066-6.00013-5  0.92
2014 Mendelsohn J, Gray JW, Howley PM, Israel MA, Thompson CB. The Molecular Basis of Cancer: Fourth Edition The Molecular Basis of Cancer: Fourth Edition. 1-863.  0.92
2013 Lu C, Venneti S, Akalin A, Fang F, Ward PS, Dematteo RG, Intlekofer AM, Chen C, Ye J, Hameed M, Nafa K, Agaram NP, Cross JR, Khanin R, Mason CE, ... ... Thompson CB, et al. Induction of sarcomas by mutant IDH2. Genes & Development. 27: 1986-98. PMID 24065766 DOI: 10.1101/gad.226753.113  0.92
2013 Lu C, Venneti S, Akalin A, Fang F, Ward PS, Dematteo RG, Intlekofer AM, Chen C, Ye J, Hameed M, Nafa K, Agaram NP, Cross JR, Khanin R, Mason CE, ... ... Thompson CB, et al. Induction of sarcomas by mutant IDH2. Genes & Development. 27: 1986-98. PMID 24065766 DOI: 10.1101/gad.226753.113  0.92
2013 Chen C, Liu Y, Lu C, Cross JR, Morris JP, Shroff AS, Ward PS, Bradner JE, Thompson C, Lowe SW. Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes & Development. 27: 1974-85. PMID 24065765 DOI: 10.1101/gad.226613.113  0.92
2013 Gentile TL, Lu C, Lodato PM, Tse S, Olejniczak SH, Witze ES, Thompson CB, Wellen KE. DNMT1 Is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation Molecular and Cellular Biology. 33: 3864-3878. PMID 23897429 DOI: 10.1128/MCB.01495-12  0.92
2013 Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/pnas.1307237110  0.92
2013 Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP, Thompson CB, Rabinowitz JD. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proceedings of the National Academy of Sciences of the United States of America. 110: 8882-7. PMID 23671091 DOI: 10.1073/pnas.1307237110  0.92
2013 Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/nature12138  0.92
2013 Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/nature12138  0.92
2013 Intlekofer AM, Thompson CB. At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy Journal of Leukocyte Biology. 94: 25-39. PMID 23625198 DOI: 10.1189/jlb.1212621  0.92
2013 Venneti S, Felicella MM, Coyne T, Phillips JJ, Gorovets D, Huse JT, Kofler J, Lu C, Tihan T, Sullivan LM, Santi M, Judkins AR, Perry A, Thompson CB. Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas. Journal of Neuropathology and Experimental Neurology. 72: 298-306. PMID 23481705 DOI: 10.1097/NEN.0b013e3182898113  0.92
2013 Finley LW, Zhang J, Ye J, Ward PS, Thompson CB. SnapShot: cancer metabolism pathways. Cell Metabolism. 17: 466-466.e2. PMID 23473039 DOI: 10.1016/j.cmet.2013.02.016  0.92
2013 Venneti S, Thompson CB. Metabolic modulation of epigenetics in gliomas. Brain Pathology (Zurich, Switzerland). 23: 217-21. PMID 23432648 DOI: 10.1111/bpa.12022  0.92
2013 Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, Heguy A, Santi M, Thompson CB, Judkins AR. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathology (Zurich, Switzerland). 23: 558-64. PMID 23414300 DOI: 10.1111/bpa.12042  0.92
2013 Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, Heguy A, Santi M, Thompson CB, Judkins AR. Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathology (Zurich, Switzerland). 23: 558-64. PMID 23414300 DOI: 10.1111/bpa.12042  0.92
2013 Ward PS, Lu C, Cross JR, Abdel-Wahab O, Levine RL, Schwartz GK, Thompson CB. The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization. The Journal of Biological Chemistry. 288: 3804-15. PMID 23264629 DOI: 10.1074/jbc.M112.435495  0.92
2013 Olejniczak SH, La Rocca G, Gruber JJ, Thompson CB. Long-lived microRNA-Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 157-62. PMID 23248281 DOI: 10.1073/pnas.1219958110  0.92
2013 Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, et al. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut. 62: 112-20. PMID 22466618 DOI: 10.1136/gutjnl-2012-302529  0.48
2012 Qing G, Li B, Vu A, Skuli N, Walton ZE, Liu X, Mayes PA, Wise DR, Thompson CB, Maris JM, Hogarty MD, Simon MC. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell. 22: 631-44. PMID 23153536 DOI: 10.1016/j.ccr.2012.09.021  0.92
2012 Vincent CT, Dass RA, Thompson CB. A dialogue with Dr. Craig B. Thompson about metabolism and its relevance for tumor growth, progression and metastasis. Seminars in Cancer Biology. 22: 484-8. PMID 22819801 DOI: 10.1016/j.semcancer.2012.07.001  0.92
2012 Cheong H, Lu C, Lindsten T, Thompson CB. Therapeutic targets in cancer cell metabolism and autophagy. Nature Biotechnology. 30: 671-8. PMID 22781696 DOI: 10.1038/nbt.2285  0.92
2012 Lu C, Thompson CB. Metabolic regulation of epigenetics. Cell Metabolism. 16: 9-17. PMID 22768835 DOI: 10.1016/j.cmet.2012.06.001  0.92
2012 Ward PS, Thompson CB. Signaling in control of cell growth and metabolism. Cold Spring Harbor Perspectives in Biology. 4: a006783. PMID 22687276 DOI: 10.1101/cshperspect.a006783  0.92
2012 Thompson C. Q&A: Craig Thompson on research joys and jobs by Suzanne Rose Cancer Discovery. 2: 6. PMID 22585149  0.92
2012 Blickwedehl J, Olejniczak S, Cummings R, Sarvaiya N, Mantilla A, Chanan-Khan A, Pandita TK, Schmidt M, Thompson CB, Bangia N. The proteasome activator PA200 regulates tumor cell responsiveness to glutamine and resistance to ionizing radiation. Molecular Cancer Research : McR. 10: 937-44. PMID 22550082 DOI: 10.1158/1541-7786.MCR-11-0493-T  0.92
2012 Ye J, Mancuso A, Tong X, Ward PS, Fan J, Rabinowitz JD, Thompson CB. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 109: 6904-9. PMID 22509023 DOI: 10.1073/pnas.1204176109  0.92
2012 Whelan RS, Konstantinidis K, Wei AC, Chen Y, Reyna DE, Jha S, Yang Y, Calvert JW, Lindsten T, Thompson CB, Crow MT, Gavathiotis E, Dorn GW, O'Rourke B, Kitsis RN. Bax regulates primary necrosis through mitochondrial dynamics. Proceedings of the National Academy of Sciences of the United States of America. 109: 6566-71. PMID 22493254 DOI: 10.1073/pnas.1201608109  0.92
2012 Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell. 21: 297-308. PMID 22439925 DOI: 10.1016/j.ccr.2012.02.014  0.92
2012 DeBerardinis RJ, Thompson CB. Cellular metabolism and disease: what do metabolic outliers teach us? Cell. 148: 1132-44. PMID 22424225 DOI: 10.1016/j.cell.2012.02.032  0.92
2012 Tai X, Van Laethem F, Pobezinsky L, Guinter T, Sharrow SO, Adams A, Granger L, Kruhlak M, Lindsten T, Thompson CB, Feigenbaum L, Singer A. Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells. Blood. 119: 5155-63. PMID 22403258 DOI: 10.1182/blood-2011-11-388918  0.92
2012 Wellen KE, Thompson CB. A two-way street: reciprocal regulation of metabolism and signalling. Nature Reviews. Molecular Cell Biology. 13: 270-6. PMID 22395772 DOI: 10.1038/nrm3305  0.92
2012 Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, ... ... Thompson CB, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 483: 474-8. PMID 22343901 DOI: 10.1038/nature10860  0.92
2012 Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 483: 479-83. PMID 22343889 DOI: 10.1038/nature10866  0.92
2012 Gruber JJ, Olejniczak SH, Yong J, La Rocca G, Dreyfuss G, Thompson CB. Ars2 promotes proper replication-dependent histone mRNA 3' end formation. Molecular Cell. 45: 87-98. PMID 22244333 DOI: 10.1016/j.molcel.2011.12.020  0.92
2012 Andreu-Agullo C, Maurin T, Thompson CB, Lai EC. Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2. Nature. 481: 195-8. PMID 22198669 DOI: 10.1038/nature10712  0.92
2012 Qu W, Oya S, Lieberman BP, Ploessl K, Wang L, Wise DR, Divgi CR, Chodosh LA, Chodosh LP, Thompson CB, Kung HF. Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 98-105. PMID 22173839 DOI: 10.2967/jnumed.111.093831  0.92
2012 Cheong H, Lindsten T, Thompson CB. Autophagy and ammonia. Autophagy. 8: 122-3. PMID 22170154 DOI: 10.4161/auto.8.1.18078  0.92
2012 Ward PS, Cross JR, Lu C, Weigert O, Abel-Wahab O, Levine RL, Weinstock DM, Sharp KA, Thompson CB. Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. Oncogene. 31: 2491-8. PMID 21996744 DOI: 10.1038/onc.2011.416  0.92
2011 Thompson CB. Rethinking the regulation of cellular metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 23-9. PMID 22429931 DOI: 10.1101/sqb.2012.76.010496  0.92
2011 Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, Simon MC, Thompson CB. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proceedings of the National Academy of Sciences of the United States of America. 108: 19611-6. PMID 22106302 DOI: 10.1073/pnas.1117773108  0.92
2011 Lieberman BP, Ploessl K, Wang L, Qu W, Zha Z, Wise DR, Chodosh LA, Belka G, Thompson CB, Kung HF. PET imaging of glutaminolysis in tumors by 18F-(2S,4R)4-fluoroglutamine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1947-55. PMID 22095958 DOI: 10.2967/jnumed.111.093815  0.92
2011 Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA. Pillars article: CTLA-4 can function as a negative regulator of T cell activation. Immunity. 1994. 1: 405-413. Journal of Immunology (Baltimore, Md. : 1950). 187: 3466-74. PMID 21934098  0.92
2011 Joo JH, Dorsey FC, Joshi A, Hennessy-Walters KM, Rose KL, McCastlain K, Zhang J, Iyengar R, Jung CH, Suen DF, Steeves MA, Yang CY, Prater SM, Kim DH, Thompson CB, et al. Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy. Molecular Cell. 43: 572-85. PMID 21855797 DOI: 10.1016/j.molcel.2011.06.018  0.92
2011 Cheong H, Lindsten T, Wu J, Lu C, Thompson CB. Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. Proceedings of the National Academy of Sciences of the United States of America. 108: 11121-6. PMID 21690395 DOI: 10.1073/pnas.1107969108  0.92
2011 Qu W, Zha Z, Lieberman BP, Mancuso A, Stetz M, Rizzi R, Ploessl K, Wise D, Thompson C, Kung HF. Facile Synthesis [5- 13C-4- 2H 2]-L-Glutamine for Hyperpolarized MRS Imaging of Cancer Cell Metabolism Academic Radiology. 18: 932-939. PMID 21658976 DOI: 10.1016/j.acra.2011.05.002  0.92
2011 Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Kalliomäki T, Elia A, Luo X, Nadeem V, Bungard D, ... ... Thompson CB, et al. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes & Development. 25: 1041-51. PMID 21576264 DOI: 10.1101/gad.1987211  0.92
2011 Qu W, Zha Z, Ploessl K, Lieberman BP, Zhu L, Wise DR, Thompson CB, Kung HF. Synthesis of optically pure 4-fluoro-glutamines as potential metabolic imaging agents for tumors. Journal of the American Chemical Society. 133: 1122-33. PMID 21190335 DOI: 10.1021/ja109203d  0.92
2011 Cheong H, Lindsten T, Wu J, Lu C, Thompson CB. Ammonia-induced autophagy is independent of ULK1/ULK2 kinases (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 27 (11121-11126) DOI: 10.1073/pnas.1107969108) Proceedings of the National Academy of Sciences of the United States of America. 108: 17856. DOI: 10.1073/pnas.1115120108  0.92
2010 Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, ... ... Thompson CB, et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 18: 553-67. PMID 21130701 DOI: 10.1016/j.ccr.2010.11.015  0.92
2010 Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes & Development. 24: 2784-99. PMID 21106670 DOI: 10.1101/gad.1985910  0.92
2010 Wellen KE, Thompson CB. Cellular metabolic stress: considering how cells respond to nutrient excess. Molecular Cell. 40: 323-32. PMID 20965425 DOI: 10.1016/j.molcel.2010.10.004  0.92
2010 Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T, Thompson CB. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL. Immunity. 1995. 3: 87-98. Journal of Immunology (Baltimore, Md. : 1950). 185: 3788-99. PMID 20858890  0.92
2010 Brown JR, Abramson J, Hochberg E, Mikler E, Dalton V, Werner L, Reynolds H, Thompson C, McDonough SM, Kuang Y, Ritz J, Neuberg D, Freedman AS. A phase i study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL Leukemia. 24: 1972-1975. PMID 20844565 DOI: 10.1038/leu.2010.199  0.92
2010 Cárdenas C, Miller RA, Smith I, Bui T, Molgó J, Müller M, Vais H, Cheung KH, Yang J, Parker I, Thompson CB, Birnbaum MJ, Hallows KR, Foskett JK. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell. 142: 270-83. PMID 20655468 DOI: 10.1016/j.cell.2010.06.007  0.92
2010 Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science (New York, N.Y.). 329: 1201-5. PMID 20647423 DOI: 10.1126/science.1191241  0.92
2010 Moser TS, Jones RG, Thompson CB, Coyne CB, Cherry S. A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics. Plos Pathogens. 6: e1000954. PMID 20585561 DOI: 10.1371/journal.ppat.1000954  0.92
2010 Wise DR, Thompson CB. Glutamine addiction: a new therapeutic target in cancer. Trends in Biochemical Sciences. 35: 427-33. PMID 20570523 DOI: 10.1016/j.tibs.2010.05.003  0.92
2010 Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... ... Thompson CB, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 465: 966. PMID 20559394 DOI: 10.1038/nature09132  0.92
2010 Kaelin WG, Thompson CB. Q&A: Cancer: clues from cell metabolism. Nature. 465: 562-4. PMID 20520704 DOI: 10.1038/465562a  0.92
2010 Krawczyk CM, Holowka T, Sun J, Blagih J, Amiel E, DeBerardinis RJ, Cross JR, Jung E, Thompson CB, Jones RG, Pearce EJ. Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation. Blood. 115: 4742-9. PMID 20351312 DOI: 10.1182/blood-2009-10-249540  0.92
2010 Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB. Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming. Oncogene. 29: 2962-72. PMID 20228846 DOI: 10.1038/onc.2010.67  0.92
2010 Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, ... Thompson CB, et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell. 17: 225-34. PMID 20171147 DOI: 10.1016/j.ccr.2010.01.020  0.92
2009 Thompson CB. Targeting the anti-apoptotic signaling pathway. Clinical Advances in Hematology & Oncology : H&O. 7: 819-22. PMID 20332754  0.92
2009 Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB. The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 106: 21660-5. PMID 19995986 DOI: 10.1073/pnas.0911316106  0.92
2009 Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, ... ... Thompson CB, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 462: 739-44. PMID 19935646 DOI: 10.1038/nature08617  0.92
2009 Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM. AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (New York, N.Y.). 326: 437-40. PMID 19833968 DOI: 10.1126/science.1172156  0.92
2009 Kong M, Ditsworth D, Lindsten T, Thompson CB. Alpha4 is an essential regulator of PP2A phosphatase activity. Molecular Cell. 36: 51-60. PMID 19818709 DOI: 10.1016/j.molcel.2009.09.025  0.92
2009 Thompson CB. Attacking cancer at its root. Cell. 138: 1051-4. PMID 19766556 DOI: 10.1016/j.cell.2009.09.002  0.92
2009 Sabin LR, Zhou R, Gruber JJ, Lukinova N, Bambina S, Berman A, Lau CK, Thompson CB, Cherry S. Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. Cell. 138: 340-51. PMID 19632183 DOI: 10.1016/j.cell.2009.04.045  0.92
2009 Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G, Thompson CB. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 138: 328-39. PMID 19632182 DOI: 10.1016/j.cell.2009.04.046  0.92
2009 Nogueira CV, Lindsten T, Jamieson AM, Case CL, Shin S, Thompson CB, Roy CR. Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. Plos Pathogens. 5: e1000478. PMID 19521510 DOI: 10.1371/journal.ppat.1000478  0.92
2009 Wellen KE, Hatzivassiliou G, Sachdeva UM, Bui TV, Cross JR, Thompson CB. ATP-citrate lyase links cellular metabolism to histone acetylation. Science (New York, N.Y.). 324: 1076-80. PMID 19461003 DOI: 10.1126/science.1164097  0.92
2009 Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science (New York, N.Y.). 324: 1029-33. PMID 19460998 DOI: 10.1126/science.1160809  0.92
2009 Madesh M, Zong WX, Hawkins BJ, Ramasamy S, Venkatachalam T, Mukhopadhyay P, Doonan PJ, Irrinki KM, Rajesh M, Pacher P, Thompson CB. Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak. Molecular and Cellular Biology. 29: 3099-112. PMID 19332555 DOI: 10.1128/MCB.01845-08  0.92
2009 Jones RG, Thompson CB. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes & Development. 23: 537-48. PMID 19270154 DOI: 10.1101/gad.1756509  0.92
2009 Thompson CB. Metabolic enzymes as oncogenes or tumor suppressors. The New England Journal of Medicine. 360: 813-5. PMID 19228626 DOI: 10.1056/NEJMe0810213  0.92
2009 Tong X, Zhao F, Thompson CB. The molecular determinants of de novo nucleotide biosynthesis in cancer cells. Current Opinion in Genetics & Development. 19: 32-7. PMID 19201187 DOI: 10.1016/j.gde.2009.01.002  0.92
2008 Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proceedings of the National Academy of Sciences of the United States of America. 105: 18782-7. PMID 19033189 DOI: 10.1073/pnas.0810199105  0.92
2008 Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA. PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 16314-9. PMID 18852460 DOI: 10.1073/pnas.0808517105  0.92
2008 Jacob DA, Ray T, Bengston CL, Lindsten T, Wu J, Thompson CB, Forger NG. The role of cell death in sexually dimorphic muscle development: male-specific muscles are retained in female bax/bak knockout mice. Developmental Neurobiology. 68: 1303-14. PMID 18563702 DOI: 10.1002/dneu.20658  0.92
2008 Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, Selak MA, Ney PA, Thompson CB. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood. 112: 1493-502. PMID 18539900 DOI: 10.1182/blood-2008-02-137398  0.92
2008 Sachdeva UM, Thompson CB. Diurnal rhythms of autophagy: implications for cell biology and human disease. Autophagy. 4: 581-9. PMID 18437053  0.92
2008 Deberardinis RJ, Sayed N, Ditsworth D, Thompson CB. Brick by brick: metabolism and tumor cell growth. Current Opinion in Genetics & Development. 18: 54-61. PMID 18387799 DOI: 10.1016/j.gde.2008.02.003  0.52
2008 DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metabolism. 7: 11-20. PMID 18177721 DOI: 10.1016/j.cmet.2007.10.002  0.92
2008 Kundu M, Thompson CB. Autophagy: basic principles and relevance to disease. Annual Review of Pathology. 3: 427-55. PMID 18039129 DOI: 10.1146/annurev.pathmechdis.2.010506.091842  0.92
2008 Woodland RT, Fox CJ, Schmidt MR, Hammerman PS, Opferman JT, Korsmeyer SJ, Hilbert DM, Thompson CB. Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. Blood. 111: 750-60. PMID 17942753 DOI: 10.1182/blood-2007-03-077222  0.92
2007 Amaravadi RK, Thompson CB. The roles of therapy-induced autophagy and necrosis in cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 7271-9. PMID 18094407 DOI: 10.1158/1078-0432.CCR-07-1595  0.92
2007 DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 19345-50. PMID 18032601 DOI: 10.1073/pnas.0709747104  0.52
2007 Jones RG, Thompson CB. Revving the engine: signal transduction fuels T cell activation. Immunity. 27: 173-8. PMID 17723208 DOI: 10.1016/j.immuni.2007.07.008  0.92
2007 Kong M, Bui TV, Ditsworth D, Gruber JJ, Goncharov D, Krymskaya VP, Lindsten T, Thompson CB. The PP2A-associated protein alpha4 plays a critical role in the regulation of cell spreading and migration. The Journal of Biological Chemistry. 282: 29712-20. PMID 17693407 DOI: 10.1074/jbc.M703159200  0.92
2007 Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, ... Thompson CB, et al. The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. Immunity. 27: 268-80. PMID 17692540 DOI: 10.1016/j.immuni.2007.05.023  0.92
2007 Buzzai M, Jones RG, Amaravadi RK, Lum JJ, DeBerardinis RJ, Zhao F, Viollet B, Thompson CB. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Research. 67: 6745-52. PMID 17638885 DOI: 10.1158/0008-5472.CAN-06-4447  0.92
2007 Li C, Wang X, Vais H, Thompson CB, Foskett JK, White C. Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proceedings of the National Academy of Sciences of the United States of America. 104: 12565-70. PMID 17636122 DOI: 10.1073/pnas.0702489104  0.92
2007 Ditsworth D, Zong WX, Thompson CB. Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. The Journal of Biological Chemistry. 282: 17845-54. PMID 17430886 DOI: 10.1074/jbc.M701465200  0.84
2007 Neill US, Thompson CB, Feldmann M, Kelley WN. A new JCI conflict-of-interest policy. The Journal of Clinical Investigation. 117: 506-8. PMID 17332875 DOI: 10.1172/JCI31587  0.92
2007 Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A, Thompson CB. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. The Journal of Clinical Investigation. 117: 326-36. PMID 17235397 DOI: 10.1172/JCI28833  0.92
2007 Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/MCB.01535-06  0.92
2006 Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB. The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1. Nature Cell Biology. 8: 170-9. PMID 16429131 DOI: 10.1038/ncb1352  0.92
2006 Zong WX, Thompson CB. Necrotic death as a cell fate. Genes & Development. 20: 1-15. PMID 16391229 DOI: 10.1101/gad.1376506  0.92
2005 Lindsten T, Zong WX, Thompson CB. Defining the role of the Bcl-2 family of proteins in the nervous system. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 11: 10-5. PMID 15632274 DOI: 10.1177/1073858404269267  0.84
2004 Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes & Development. 18: 1272-82. PMID 15145826 DOI: 10.1101/gad.1199904  0.84
2004 Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS. c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1. The Journal of Biological Chemistry. 279: 4305-12. PMID 14627695 DOI: 10.1074/jbc.M312241200  0.92
2003 Lindsten T, Golden JA, Zong WX, Minarcik J, Harris MH, Thompson CB. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11112-9. PMID 14657169  0.92
2003 Johnson TR, Stone K, Nikrad M, Yeh T, Zong WX, Thompson CB, Nesterov A, Kraft AS. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene. 22: 4953-63. PMID 12902978 DOI: 10.1038/sj.onc.1206656  0.84
2003 Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis Journal of Cell Biology. 162: 59-69. PMID 12847083 DOI: 10.1083/jcb.200302084  0.92
2002 Rathmell JC, Lindsten T, Zong WX, Cinalli RM, Thompson CB. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nature Immunology. 3: 932-9. PMID 12244308 DOI: 10.1038/ni834  0.92
2002 Vander Heiden MG, Choy JS, VanderWeele DJ, Brace JL, Harris MH, Bauer DE, Prange B, Kron SJ, Thompson CB, Rudin CM. Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism. The Journal of Biological Chemistry. 277: 44870-6. PMID 12244097 DOI: 10.1074/jbc.M204888200  0.92
2002 Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, Davis RJ. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Molecular and Cellular Biology. 22: 4929-42. PMID 12052897 DOI: 10.1128/MCB.22.13.4929-4942.2002  0.92
2002 McClintock DS, Santore MT, Lee VY, Brunelle J, Budinger GR, Zong WX, Thompson CB, Hay N, Chandel NS. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Molecular and Cellular Biology. 22: 94-104. PMID 11739725  0.84
2001 Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, Thompson CB. Growth factors can influence cell growth and survival through effects on glucose metabolism Molecular and Cellular Biology. 21: 5899-5912. PMID 11486029 DOI: 10.1128/MCB.21.17.5899-5912.2001  0.92
2001 Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB, Colombini M. Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. The Journal of Biological Chemistry. 276: 19414-9. PMID 11259441 DOI: 10.1074/jbc.M101590200  0.92
2000 Rathmell JC, Vander Heiden MG, Harris MH, Frauwirth KA, Thompson CB. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Molecular Cell. 6: 683-92. PMID 11030347  0.92
2000 Chuang E, Fisher TS, Morgan RW, Robbins MD, Duerr JM, Vander Heiden MG, Gardner JP, Hambor JE, Neveu MJ, Thompson CB. The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A Immunity. 13: 313-322. PMID 11021529  0.92
2000 Chandel NS, Vander Heiden MG, Thompson CB, Schumacker PT. Redox regulation of p53 during hypoxia Oncogene. 19: 3840-3848. PMID 10951577  0.92
2000 Gottlieb E, Vander Heiden MG, Thompson CB. Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis Molecular and Cellular Biology. 20: 5680-5689. PMID 10891504 DOI: 10.1128/MCB.20.15.5680-5689.2000  0.92
2000 Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, Thompson CB. Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proceedings of the National Academy of Sciences of the United States of America. 97: 4666-71. PMID 10781072 DOI: 10.1073/pnas.090082297  0.92
2000 Harris MH, Vander Heiden MG, Kron SJ, Thompson CB. Role of oxidative phosphorylation in Bax toxicity Molecular and Cellular Biology. 20: 3590-3596. PMID 10779348 DOI: 10.1128/MCB.20.10.3590-3596.2000  0.92
1999 Thompson CB, Rathmell JC, Frauwirth KA, Lindsten T, Rudin CM, Opferman JT, Ashton-Rickardt PG, Harris MH, Chandel NS, Schumacker PT, Vander Heiden MG. What keeps a resting T cell alive? Cold Spring Harbor Symposia On Quantitative Biology. 64: 383-7. PMID 11232311  0.92
1999 Vander Heiden MG, Thompson CB. Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis? Nature Cell Biology. 1: E209-E216. PMID 10587660  0.92
1999 Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB. Bcl-x(L) prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange Molecular Cell. 3: 159-167. PMID 10078199 DOI: 10.1016/S1097-2765(00)80307-X  0.92
1999 Minn AJ, Kettlun CS, Liang H, Kelekar A, Vander Heiden MG, Chang BS, Fesik SW, Fill M, Thompson CB. Bcl-x(L) regulates apoptosis by heterodimerization-dependent and -independent mechanisms Embo Journal. 18: 632-643. PMID 9927423 DOI: 10.1093/emboj/18.3.632  0.92
1997 Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria Cell. 91: 627-637. PMID 9393856  0.92
1997 Chuang E, Alegre ML, Duckett CS, Noel PJ, Vander Heiden MG, Thompson CB. Interaction of CTLA-4 with the Clathrin-Associated Protein AP50 Results in Ligand-Independent Endocytosis That Limits Cell Surface Expression Journal of Immunology. 159: 144-151. PMID 9200449  0.92
1986 Thompson CB, Thomas ED. Bone marrow transplantation. The Surgical Clinics of North America. 66: 589-601. PMID 3520897  0.92
1986 Thompson CB, Sanders JE, Flournoy N, Buckner CD, Thomas ED. The risks of central nervous system relapse and leukoencephalopathy in patients receiving marrow transplants for acute leukemia. Blood. 67: 195-9. PMID 3510066  0.92
1985 June CH, Thompson CB, Kennedy MS, Nims J, Thomas ED. Profound hypomagnesemia and renal magnesium wasting associated with the use of cyclosporine for marrow transplantation. Transplantation. 39: 620-4. PMID 3890292  0.92
1984 Thompson CB, June CH, Sullivan KM, Thomas ED. Association between cyclosporin neurotoxicity and hypomagnesaemia. Lancet. 2: 1116-20. PMID 6150182  0.92
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