Leslie Joan Berg - Publications

Affiliations: 
1990-1998 Molecular and Cellular Biology Harvard University, Cambridge, MA, United States 
 1998- Pathology University of Massachusetts Medical School, Worcester, MA, United States 
Area:
Immunology and Virology
Website:
https://profiles.umassmed.edu/display/132441

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Perrenoud L, Conley J, Berg LJ. Analysis of T-cell Receptor-Induced Calcium Influx in Primary Murine T-cells by Full Spectrum Flow Cytometry. Journal of Visualized Experiments : Jove. PMID 36591968 DOI: 10.3791/64526  0.313
2021 Forconi CS, Mulama DH, Saikumar Lakshmi P, Foley J, Otieno JA, Kurtis JD, Berg LJ, Ong'echa JM, Münz C, Moormann AM. Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4 and CD8 T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma. Cancers. 13. PMID 34771539 DOI: 10.3390/cancers13215375  0.392
2021 Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34452995 DOI: 10.1073/pnas.2025825118  0.466
2020 Conley JM, Gallagher MP, Rao A, Berg LJ. Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength. Journal of Immunology (Baltimore, Md. : 1950). PMID 32493815 DOI: 10.4049/Jimmunol.1900853  0.524
2020 Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8 T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 4: 57-71. PMID 32034085 DOI: 10.4049/immunohorizons.1900093  0.49
2019 Conley JM, Berg LJ. TCR signaling: it's all about the numbers. Nature Immunology. PMID 31591572 DOI: 10.1038/S41590-019-0520-0  0.496
2019 Cho HS, Reboldi A, Hall JA, Berg LJ. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine. Nature Communications. 10: 784. PMID 30770814 DOI: 10.1038/S41467-019-08699-9  0.317
2018 Olesin E, Nayar R, Saikumar-Lakshmi P, Berg LJ. The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8 Memory T Cells. Immunohorizons. 2: 251-261. PMID 30264035 DOI: 10.4049/immunohorizons.1800046  0.383
2018 Gallagher MP, Conley JM, Berg LJ. Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8 T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei. Immunohorizons. 2: 208-215. PMID 30221251 DOI: 10.4049/immunohorizons.1800032  0.438
2018 Andreotti AH, Joseph RE, Conley JM, Iwasa J, Berg LJ. Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. Annual Review of Immunology. 36: 549-578. PMID 29677469 DOI: 10.1146/Annurev-Immunol-042617-053344  0.533
2017 Shin HM, Kapoor VN, Kim G, Li P, Kim HR, Suresh M, Kaech SM, Wherry EJ, Selin LK, Leonard WJ, Welsh RM, Berg LJ. Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. Plos Pathogens. 13: e1006544. PMID 28827827 DOI: 10.1371/Journal.Ppat.1006544  0.489
2017 Falanga YT, Frascoli M, Kaymaz Y, Forconi C, Ong'echa JM, Bailey JA, Berg LJ, Moormann AM. High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells. Jci Insight. 2. PMID 28768916 DOI: 10.1172/Jci.Insight.93814  0.521
2017 Gallagher MP, Berg LJ. Gene-enhancer variants reveal diverse TCR-mediated differentiation. Nature Immunology. 18: 483-484. PMID 28418392 DOI: 10.1038/Ni.3729  0.402
2016 Marshall NB, Vong AM, Devarajan P, Brauner MD, Kuang Y, Nayar R, Schutten EA, Castonguay CH, Berg LJ, Nutt SL, Swain SL. NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28031335 DOI: 10.4049/Jimmunol.1601297  0.441
2016 Urban SL, Berg LJ, Welsh RM. Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity. Virology. 493: 52-9. PMID 26999026 DOI: 10.1016/J.Virol.2016.03.005  0.534
2016 Conley JM, Gallagher MP, Berg LJ. T Cells and Gene Regulation: The Switching On and Turning Up of Genes after T Cell Receptor Stimulation in CD8 T Cells. Frontiers in Immunology. 7: 76. PMID 26973653 DOI: 10.3389/Fimmu.2016.00076  0.586
2016 Sharma S, Campbell AM, Chan J, Schattgen SA, Orlowski GM, Nayar R, Huyler AH, Nündel K, Mohan C, Berg LJ, Shlomchik MJ, Marshak-Rothstein A, Fitzgerald KA. II-13 Suppression of systemic autoimmunity by the innate immune adaptor sting Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.43  0.314
2015 Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection. Plos One. 10: e0144826. PMID 26714260 DOI: 10.1371/Journal.Pone.0144826  0.544
2015 Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ. A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression. Journal of Immunology (Baltimore, Md. : 1950). PMID 26466958 DOI: 10.4049/Jimmunol.1501828  0.532
2015 Wu T, Shin HM, Moseman EA, Ji Y, Huang B, Harly C, Sen JM, Berg LJ, Gattinoni L, McGavern DB, Schwartzberg PL. TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. Cell Reports. PMID 26365183 DOI: 10.1016/J.Celrep.2015.08.049  0.421
2015 Sharma S, Campbell AM, Chan J, Schattgen SA, Orlowski GM, Nayar R, Huyler AH, Nündel K, Mohan C, Berg LJ, Shlomchik MJ, Marshak-Rothstein A, Fitzgerald KA. Suppression of systemic autoimmunity by the innate immune adaptor STING. Proceedings of the National Academy of Sciences of the United States of America. 112: E710-7. PMID 25646421 DOI: 10.1073/Pnas.1420217112  0.322
2015 Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 regulates the ratio of T-Bet to eomesodermin in CD8+ T cells responding to persistent LCMV infection Plos One. 10. DOI: 10.1371/journal.pone.0144826  0.402
2014 Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A. Jarid2 is induced by TCR signalling and controls iNKT cell maturation. Nature Communications. 5: 4540. PMID 25105474 DOI: 10.1038/Ncomms5540  0.484
2014 Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ. Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways. Journal of Immunology (Baltimore, Md. : 1950). 193: 688-99. PMID 24943215 DOI: 10.4049/Jimmunol.1302059  0.543
2014 Kapoor VN, Shin HM, Cho OH, Berg LJ, Kang J, Welsh RM. Regulation of tissue-dependent differences in CD8+ T cell apoptosis during viral infection. Journal of Virology. 88: 9490-503. PMID 24942579 DOI: 10.1128/Jvi.01223-14  0.486
2014 Prince AL, Watkin LB, Yin CC, Selin LK, Kang J, Schwartzberg PL, Berg LJ. Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk. Journal of Immunology (Baltimore, Md. : 1950). 193: 673-87. PMID 24928994 DOI: 10.4049/Jimmunol.1302058  0.549
2014 Nayar R, Schutten E, Bautista B, Daniels K, Prince AL, Enos M, Brehm MA, Swain SL, Welsh RM, Berg LJ. Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 5881-93. PMID 24835398 DOI: 10.4049/Jimmunol.1303187  0.511
2013 Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nature Medicine. 19: 1632-7. PMID 24270545 DOI: 10.1038/Nm.3393  0.556
2013 Shin HM, Kapoor VN, Guan T, Kaech SM, Welsh RM, Berg LJ. Epigenetic modifications induced by Blimp-1 Regulate CD8⁺ T cell memory progression during acute virus infection. Immunity. 39: 661-75. PMID 24120360 DOI: 10.1016/J.Immuni.2013.08.032  0.466
2013 Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Science Signaling. 6: ra76. PMID 23982207 DOI: 10.1126/Scisignal.2004298  0.592
2013 Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J. A network of high-mobility group box transcription factors programs innate interleukin-17 production. Immunity. 38: 681-93. PMID 23562159 DOI: 10.1016/J.Immuni.2013.01.010  0.394
2013 Yin CC, Cho OH, Sylvia KE, Narayan K, Prince AL, Evans JW, Kang J, Berg LJ. The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 2659-69. PMID 23378428 DOI: 10.4049/Jimmunol.1202531  0.534
2012 Berg LJ. Signaling pathways that regulate T cell development and differentiation. Journal of Immunology (Baltimore, Md. : 1950). 189: 5487-8. PMID 23225893 DOI: 10.4049/Jimmunol.1290076  0.404
2012 Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ. TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: E2794-802. PMID 23011795 DOI: 10.1073/Pnas.1205742109  0.585
2012 Narayan K, Sylvia KE, Malhotra N, Yin CC, Martens G, Vallerskog T, Kornfeld H, Xiong N, Cohen NR, Brenner MB, Berg LJ, Kang J. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nature Immunology. 13: 511-8. PMID 22473038 DOI: 10.1038/Ni.2247  0.521
2011 Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, et al. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity. 34: 492-504. PMID 21497118 DOI: 10.1016/J.Immuni.2011.03.017  0.531
2010 Marshall HD, Prince AL, Berg LJ, Welsh RM. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. Journal of Immunology (Baltimore, Md. : 1950). 185: 1419-28. PMID 20592282 DOI: 10.4049/Jimmunol.1001140  0.507
2010 Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/Cshperspect.A002287  0.62
2010 Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Disrupting the intermolecular self-association of Itk enhances T cell signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 4228-35. PMID 20237289 DOI: 10.4049/Jimmunol.0901908  0.544
2009 Berg LJ. Strength of T cell receptor signaling strikes again. Immunity. 31: 529-31. PMID 19833081 DOI: 10.1016/J.Immuni.2009.09.008  0.523
2009 Shi M, Lin TH, Appell KC, Berg LJ. Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals. Journal of Immunology (Baltimore, Md. : 1950). 183: 4493-501. PMID 19734221 DOI: 10.4049/Jimmunol.0804339  0.569
2009 Sacristán C, Schattgen SA, Berg LJ, Bunnell SC, Roy AL, Rosenstein Y. Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. European Journal of Immunology. 39: 2584-95. PMID 19701889 DOI: 10.1002/Eji.200839031  0.797
2009 Felices M, Yin CC, Kosaka Y, Kang J, Berg LJ. Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 8308-13. PMID 19416854 DOI: 10.1073/Pnas.0808459106  0.574
2009 Prince AL, Yin CC, Enos ME, Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunological Reviews. 228: 115-31. PMID 19290924 DOI: 10.1111/J.1600-065X.2008.00746.X  0.627
2008 Wu W, Berg LJ. c-Abl, an additional tyrosine kinase required for T cell development and function. Cell Cycle (Georgetown, Tex.). 7: 3791. PMID 19151583 DOI: 10.4161/Cc.7.24.7514  0.535
2008 Berg LJ. The "bubble boy" paradox: an answer that led to a question. Journal of Immunology (Baltimore, Md. : 1950). 181: 5815-6. PMID 18941168 DOI: 10.4049/Jimmunol.181.9.5815  0.377
2008 Shi M, Lin TH, Appell KC, Berg LJ. Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation. Immunity. 28: 763-73. PMID 18549798 DOI: 10.1016/J.Immuni.2008.04.016  0.585
2008 Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 3007-18. PMID 18292523 DOI: 10.4049/Jimmunol.180.5.3007  0.589
2008 Prince AL, Marshall HD, Atherly LO, Lucas JA, Felices M, Berg LJ. The role of tec kinases in CD8+ T cell memory differentiation The Faseb Journal. 22: 511-511. DOI: 10.1096/Fasebj.22.2_Supplement.511  0.5
2007 Lucas JA, Felices M, Evans JW, Berg LJ. Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk. Journal of Immunology (Baltimore, Md. : 1950). 179: 7561-7. PMID 18025201 DOI: 10.4049/Jimmunol.179.11.7561  0.593
2007 Berg LJ. Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. Nature Reviews. Immunology. 7: 479-85. PMID 17479128 DOI: 10.1038/Nri2091  0.571
2007 Felices M, Falk M, Kosaka Y, Berg LJ. Tec kinases in T cell and mast cell signaling. Advances in Immunology. 93: 145-84. PMID 17383541 DOI: 10.1016/S0065-2776(06)93004-1  0.577
2006 Kosaka Y, Felices M, Berg LJ. Itk and Th2 responses: action but no reaction. Trends in Immunology. 27: 453-60. PMID 16931156 DOI: 10.1016/J.It.2006.08.006  0.564
2006 Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ. The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. Immunity. 25: 79-91. PMID 16860759 DOI: 10.1016/J.Immuni.2006.05.012  0.552
2006 Mayack SR, Berg LJ. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. Journal of Immunology (Baltimore, Md. : 1950). 176: 2059-63. PMID 16455959 DOI: 10.4049/Jimmunol.176.4.2059  0.571
2006 Atherly LO, Brehm MA, Welsh RM, Berg LJ. Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help. Journal of Immunology (Baltimore, Md. : 1950). 176: 1571-81. PMID 16424186 DOI: 10.4049/Jimmunol.176.3.1571  0.6
2005 Li CR, Berg LJ. Itk is not essential for CD28 signaling in naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 4475-9. PMID 15814667 DOI: 10.4049/Jimmunol.174.8.4475  0.493
2005 Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annual Review of Immunology. 23: 549-600. PMID 15771581 DOI: 10.1146/Annurev.Immunol.22.012703.104743  0.563
2004 Miller AT, Wilcox HM, Lai Z, Berg LJ. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet. Immunity. 21: 67-80. PMID 15345221 DOI: 10.1016/J.Immuni.2004.06.009  0.799
2004 Berg LJ, Nussenzweig M. Signals that regulate lymphocyte development and differentiation. Current Opinion in Immunology. 16: 163-6. PMID 15023408 DOI: 10.1016/J.Coi.2004.02.007  0.357
2003 Wilcox HM, Berg LJ. Itk phosphorylation sites are required for functional activity in primary T cells. The Journal of Biological Chemistry. 278: 37112-21. PMID 12842872 DOI: 10.1074/Jbc.M304811200  0.815
2003 Lucas JA, Miller AT, Atherly LO, Berg LJ. The role of Tec family kinases in T cell development and function. Immunological Reviews. 191: 119-38. PMID 12614356 DOI: 10.1034/J.1600-065X.2003.00029.X  0.591
2002 Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Mechanisms of Development. 119: S225-9. PMID 14516690 DOI: 10.1016/S0925-4773(03)00121-7  0.412
2002 Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Gene Expression Patterns : Gep. 2: 261-5. PMID 12617812 DOI: 10.1016/S1567-133X(02)00054-6  0.413
2002 Lucas JA, Atherly LO, Berg LJ. The absence of Itk inhibits positive selection without changing lineage commitment. Journal of Immunology (Baltimore, Md. : 1950). 168: 6142-51. PMID 12055226 DOI: 10.4049/Jimmunol.168.12.6142  0.574
2002 Miller AT, Berg LJ. New insights into the regulation and functions of Tec family tyrosine kinases in the immune system. Current Opinion in Immunology. 14: 331-40. PMID 11973131 DOI: 10.1016/S0952-7915(02)00345-X  0.488
2002 Miller AT, Berg LJ. Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase. Journal of Immunology (Baltimore, Md. : 1950). 168: 2163-72. PMID 11859102 DOI: 10.4049/Jimmunol.168.5.2163  0.568
2001 Soldevila G, Castellanos C, Malissen M, Berg LJ. Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization. Cellular Immunology. 214: 123-38. PMID 12088411 DOI: 10.1006/Cimm.2001.1892  0.575
2001 Berg LJ, Kang J. Molecular determinants of TCR expression and selection. Current Opinion in Immunology. 13: 232-41. PMID 11228418 DOI: 10.1016/S0952-7915(00)00209-0  0.499
2001 Gozalo-Sanmillan S, McNally JM, Lin MY, Chambers CA, Berg LJ. Cutting edge: Two distinct mechanisms lead to impaired T cell homeostasis in Janus kinase 3-and CTLA-4-deficient mice Journal of Immunology. 166: 727-730. PMID 11145642 DOI: 10.4049/Jimmunol.166.2.727  0.592
2001 Yang WC, Ching KA, Tsoukas CD, Berg LJ. Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain. Journal of Immunology (Baltimore, Md. : 1950). 166: 387-95. PMID 11123316 DOI: 10.4049/Jimmunol.166.1.387  0.557
2000 Baird AM, Lucas JA, Berg LJ. A profound deficiency in thymic progenitor cells in mice lacking Jak3. Journal of Immunology (Baltimore, Md. : 1950). 165: 3680-8. PMID 11034372 DOI: 10.4049/Jimmunol.165.7.3680  0.501
2000 Berg L, Rönnelid J, Klareskog L, Bucht A. Down-regulation of the T cell receptor CD3 zeta chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness. Clinical and Experimental Immunology. 120: 174-182. PMID 10759780 DOI: 10.1046/J.1365-2249.2000.01180.X  0.473
2000 Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. The Journal of Biological Chemistry. 275: 2219-30. PMID 10636929 DOI: 10.1074/Jbc.275.3.2219  0.753
1999 Thomis DC, Aramburu J, Berg LJ. The Jak family tyrosine kinase Jak3 is required for IL-2 synthesis by naive/resting CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 163: 5411-7. PMID 10553066  0.508
1999 Baird AM, Gerstein RM, Berg LJ. The role of cytokine receptor signaling in lymphocyte development. Current Opinion in Immunology. 11: 157-66. PMID 10322150 DOI: 10.1016/S0952-7915(99)80027-2  0.419
1999 Yelon D, Schaefer KL, Berg LJ. Alterations in CD4-binding regions of the MHC class II molecule I-Ek do not impede CD4+ T cell development. Journal of Immunology (Baltimore, Md. : 1950). 162: 1348-58. PMID 9973389  0.339
1999 Grossman WJ, Verbsky JW, Yang L, Berg LJ, Fields LE, Chaplin DD, Ratner L. Dysregulated Myelopoiesis in Mice Lacking Jak3 Blood. 94: 932-939. DOI: 10.1182/Blood.V94.3.932.415K30_932_939  0.421
1998 Durum SK, Candèias S, Nakajima H, Leonard WJ, Baird AM, Berg LJ, Muegge K. Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. The Journal of Experimental Medicine. 188: 2233-41. PMID 9858510 DOI: 10.1084/Jem.188.12.2233  0.432
1998 Bunnell SC, Berg LJ. The signal transduction of motion and antigen recognition: factors affecting T cell function and differentiation. Genetic Engineering. 20: 63-110. PMID 9666556 DOI: 10.1007/978-1-4899-1739-3_4  0.732
1998 Baird AM, Thomis DC, Berg LJ. T cell development and activation in Jak3-deficient mice. Journal of Leukocyte Biology. 63: 669-77. PMID 9620658 DOI: 10.1002/Jlb.63.6.669  0.48
1998 Liu KQ, Bunnell SC, Gurniak CB, Berg LJ. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. The Journal of Experimental Medicine. 187: 1721-7. PMID 9584150 DOI: 10.1084/Jem.187.10.1721  0.75
1997 Thomis DC, Lee W, Berg LJ. T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 159: 4708-19. PMID 9366394  0.497
1997 Heyeck SD, Wilcox HM, Bunnell SC, Berg LJ. Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity. The Journal of Biological Chemistry. 272: 25401-8. PMID 9312162 DOI: 10.1074/Jbc.272.40.25401  0.757
1997 Thomis DC, Berg LJ. The role of Jak3 in lymphoid development, activation, and signaling. Current Opinion in Immunology. 9: 541-7. PMID 9287175 DOI: 10.1016/S0952-7915(97)80108-2  0.414
1997 Gurniak CB, Thomis DC, Berg LJ. Genomic structure and promoter region of the murine Janus-family tyrosine kinase, Jak3. Dna and Cell Biology. 16: 85-94. PMID 9022047 DOI: 10.1089/Dna.1997.16.85  0.4
1997 Thomis DC, Berg LJ. Peripheral expression of Jak3 is required to maintain T lymphocyte function. The Journal of Experimental Medicine. 185: 197-206. PMID 9016869 DOI: 10.1084/Jem.185.2.197  0.546
1997 Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature. 385: 93-7. PMID 8985255 DOI: 10.1038/385093A0  0.748
1996 Bunnell SC, Henry PA, Kolluri R, Kirchhausen T, Rickles RJ, Berg LJ. Identification of Itk/Tsk Src homology 3 domain ligands. The Journal of Biological Chemistry. 271: 25646-56. PMID 8810341 DOI: 10.1074/Jbc.271.41.25646  0.748
1996 Kammer W, Lischke A, Moriggl R, Groner B, Ziemiecki A, Gurniak CB, Berg LJ, Friedrich K. Homodimerization of interleukin-4 receptor alpha chain can induce intracellular signaling. The Journal of Biological Chemistry. 271: 23634-7. PMID 8798580 DOI: 10.1074/Jbc.271.39.23634  0.411
1996 Gurniak CB, Berg LJ. A new member of the Eph family of receptors that lacks protein tyrosine kinase activity. Oncogene. 13: 777-86. PMID 8761299  0.351
1996 Lyons DS, Lieberman SA, Hampl J, Boniface JJ, Chien YH, Berg LJ, Davis MM. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists Immunity. 5: 53-61. PMID 8758894 DOI: 10.1016/S1074-7613(00)80309-X  0.449
1996 Yelon D, Spain LM, Lim K, Berg LJ. Alterations in CD4 dependence accompany T cell development and differentiation International Immunology. 8: 1077-1090. PMID 8757953 DOI: 10.1093/Intimm/8.7.1077  0.505
1996 Gurniak CB, Berg LJ. Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells. Blood. 87: 3151-60. PMID 8605329 DOI: 10.1182/Blood.V87.8.3151.Bloodjournal8783151  0.561
1995 Liao JC, Berg LJ, Jay DG. Chromophore-assisted laser inactivation of subunits of the T-cell receptor in living cells is spatially restricted Photochemistry and Photobiology. 62: 923-929. PMID 8570733 DOI: 10.1111/J.1751-1097.1995.Tb09157.X  0.424
1995 Stowers L, Yelon D, Berg LJ, Chant J. Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42. Proceedings of the National Academy of Sciences of the United States of America. 92: 5027-31. PMID 7761442 DOI: 10.1073/Pnas.92.11.5027  0.484
1995 Lieberman SA, Spain LM, Wang L, Berg LJ. Enhanced T cell maturation and altered lineage commitment in T cell receptor/CD4-transgenic mice Cellular Immunology. 162: 56-67. PMID 7704911 DOI: 10.1006/Cimm.1995.1051  0.484
1995 Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 8891-5. PMID 7568038 DOI: 10.1073/Pnas.92.19.8891  0.761
1995 Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3 Science. 270: 794-797. PMID 7481767 DOI: 10.1126/Science.270.5237.794  0.432
1994 Spain LM, Jorgensen JL, Davis MM, Berg LJ. A peptide antigen antagonist prevents the differentiation of T cell receptor transgenic thymocytes Journal of Immunology. 152: 1709-1717. PMID 8120380  0.372
1994 Spain LM, Yelon D, Berg LJ. Do the CD4 and CD8 lineages represent parallel pathways? Seminars in Immunology. 6: 213-220. PMID 8000030 DOI: 10.1006/Smim.1994.1028  0.403
1994 Sakaguchi S, Ermak TH, Toda M, Berg LJ, Ho W, Fazekas De St. Groth B, Peterson PA, Sakaguchi N, Davis MM. Induction of autoimmune disease in mice by germline alteration of the T cell receptor gene expression Journal of Immunology. 152: 1471-1484. PMID 7905503  0.364
1994 Spain LM, Berg LJ. Quantitative Analysis of the Efficiency of Clonal Deletion in the Thymus Developmental Immunology. 4: 43-53. PMID 7620325 DOI: 10.1155/1994/92025  0.404
1993 Heyeck SD, Berg LJ. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proceedings of the National Academy of Sciences of the United States of America. 90: 669-73. PMID 8421704 DOI: 10.1073/Pnas.90.2.669  0.606
1992 Spain LM, Berg LJ. Developmental regulation of thymocyte susceptibility to deletion by 'self'-peptide Journal of Experimental Medicine. 176: 213-223. PMID 1319457 DOI: 10.1084/Jem.176.1.213  0.373
1990 Berg LJ, Frank GD, Davis MM. The effects of MHC gene dosage and allelic variation on T cell receptor selection. Cell. 60: 1043-53. PMID 2317862 DOI: 10.1016/0092-8674(90)90352-F  0.545
1990 Davis MM, Groth BFDS, Berg LJ, Lin A, Devaux B, Sagerstrom C, Elliott JF, Bjorkman PJ. Chapter 13 Selection of an αβ T-Cell Antigen Receptor in Vivo and Expression in Vitro in a Soluble Form Current Topics in Membranes and Transport. 36: 155-160. DOI: 10.1016/S0070-2161(08)60175-6  0.7
1989 Berg LJ, Davis MM. T-cell development in T cell receptor alphabeta transgenic mice Seminars in Immunology. 1: 105-116. PMID 15630812  0.438
1989 Davis MM, Berg LJ, Lin AY, Fazekas de St Groth B, Devaux B, Sagerstrom CG, Bjorkman PJ, Elliott JF. TCR recognition and selection in vivo. Cold Spring Harbor Symposia On Quantitative Biology. 54: 119-28. PMID 2700932 DOI: 10.1101/Sqb.1989.054.01.015  0.607
1989 Berg LJ. Generation of the T cell repertoire. Current Opinion in Immunology. 2: 87-92. PMID 2692626 DOI: 10.1016/0952-7915(89)90102-7  0.5
1989 Berg LJ, Fazekas de St Groth B, Pullen AM, Davis MM. Phenotypic differences between alpha beta versus beta T-cell receptor transgenic mice undergoing negative selection. Nature. 340: 559-62. PMID 2528070 DOI: 10.1038/340559A0  0.555
1989 Berg LJ, Pullen AM, Fazekas de St Groth B, Mathis D, Benoist C, Davis MM. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell. 58: 1035-46. PMID 2476238 DOI: 10.1016/0092-8674(89)90502-3  0.602
1988 Berg LJ, Fazekas de St Groth B, Ivars F, Goodnow CC, Gilfillan S, Garchon HJ, Davis MM. Expression of T-cell receptor alpha-chain genes in transgenic mice. Molecular and Cellular Biology. 8: 5459-69. PMID 3266655 DOI: 10.1128/Mcb.8.12.5459  0.571
1986 Berg LJ, Singh K, Botchan M. Complementation of a bovine papilloma virus low-copy-number mutant: Evidence for a temporal requirement of the complementing gene Molecular and Cellular Biology. 6: 859-869. PMID 3022134 DOI: 10.1128/Mcb.6.3.859  0.52
1986 Berg L, Lusky M, Stenlund A, Botchan MR. Repression of bovine papilloma virus replication is mediated by a virally encoded trans-acting factor. Cell. 46: 753-62. PMID 3017567 DOI: 10.1016/0092-8674(86)90351-X  0.523
1986 Botchan M, Berg L, Reynolds J, Lusky M. The bovine papillomavirus replicon Ciba Foundation Symposium. 120: 53-67. PMID 3013526  0.519
1983 Lusky M, Berg L, Weiher H, Botchan M. Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit. Molecular and Cellular Biology. 3: 1108-22. PMID 6308425 DOI: 10.1128/Mcb.3.6.1108  0.524
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