Robert S. Adelstein, M.D. - Publications

Affiliations: 
1961- Molecular Cardiology National Institutes of Health, Bethesda, MD 
Area:
myosin
Website:
https://irp.nih.gov/pi/robert-adelstein

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhang Y, Liu C, Adelstein RS, Ma X. Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice. Molecular Biology of the Cell. mbcE17120713. PMID 30044719 DOI: 10.1091/mbc.E17-12-0713  1
2017 Haque F, Kaku Y, Fujimura S, Ohmori T, Adelstein RS, Nishinakamura R. Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia. Developmental Biology. PMID 28478097 DOI: 10.1016/j.ydbio.2017.04.020  1
2016 Naydenov NG, Feygin A, Wang D, Kuemmerle JF, Harris G, Conti MA, Adelstein RS, Ivanov AI. Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental Colitis. Scientific Reports. 6: 24161. PMID 27063635 DOI: 10.1038/srep24161  1
2015 Anne Conti M, Saleh AD, Brinster LR, Cheng H, Chen Z, Cornelius S, Liu C, Ma X, Van Waes C, Adelstein RS. Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma. Scientific Reports. 5: 14068. PMID 26369831 DOI: 10.1038/srep14068  1
2015 Kwan R, Chen L, Looi K, Tao GZ, Weerasinghe SV, Snider NT, Conti MA, Adelstein RS, Xie Q, Omary MB. PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding. Hepatology (Baltimore, Md.). PMID 26126491 DOI: 10.1002/hep.27965  1
2015 Chabaud M, Heuzé ML, Bretou M, Vargas P, Maiuri P, Solanes P, Maurin M, Terriac E, Le Berre M, Lankar D, Piolot T, Adelstein RS, Zhang Y, Sixt M, Jacobelli J, et al. Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nature Communications. 6: 7526. PMID 26109323 DOI: 10.1038/ncomms8526  1
2015 Elliott H, Fischer RS, Myers KA, Desai RA, Gao L, Chen CS, Adelstein RS, Waterman CM, Danuser G. Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature. Nature Cell Biology. 17: 137-47. PMID 25621949 DOI: 10.1038/ncb3092  1
2015 Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R. Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons. Journal of the American Society of Nephrology : Jasn. 26: 1081-91. PMID 25168025 DOI: 10.1681/ASN.2014030281  1
2014 Hasumi Y, Baba M, Hasumi H, Huang Y, Lang M, Reindorf R, Oh HB, Sciarretta S, Nagashima K, Haines DC, Schneider MD, Adelstein RS, Schmidt LS, Sadoshima J, Marston Linehan W. Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation. Human Molecular Genetics. 23: 5706-19. PMID 24908670 DOI: 10.1093/hmg/ddu286  1
2014 Chandrasekar I, Goeckeler ZM, Turney SG, Wang P, Wysolmerski RB, Adelstein RS, Bridgman PC. Nonmuscle myosin II is a critical regulator of clathrin-mediated endocytosis. Traffic (Copenhagen, Denmark). 15: 418-32. PMID 24443954 DOI: 10.1111/tra.12152  1
2013 Luccardini C, Hennekinne L, Viou L, Yanagida M, Murakami F, Kessaris N, Ma X, Adelstein RS, Mège RM, Métin C. N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18149-60. PMID 24227724 DOI: 10.1523/JNEUROSCI.0593-13.2013  1
2013 Billington N, Wang A, Mao J, Adelstein RS, Sellers JR. Characterization of three full-length human nonmuscle myosin II paralogs. The Journal of Biological Chemistry. 288: 33398-410. PMID 24072716 DOI: 10.1074/jbc.M113.499848  1
2013 Ebrahim S, Fujita T, Millis BA, Kozin E, Ma X, Kawamoto S, Baird MA, Davidson M, Yonemura S, Hisa Y, Conti MA, Adelstein RS, Sakaguchi H, Kachar B. NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Current Biology : Cb. 23: 731-6. PMID 23562268 DOI: 10.1016/j.cub.2013.03.039  1
2012 He Y, Beatty A, Han X, Ji Y, Ma X, Adelstein RS, Yates JR, Kemphues K, Qi L. Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Developmental Cell. 23: 1141-52. PMID 23237951 DOI: 10.1016/j.devcel.2012.11.006  1
2012 Yang F, Wei Q, Adelstein RS, Wang PJ. Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions. Developmental Biology. 369: 356-61. PMID 22820068 DOI: 10.1016/j.ydbio.2012.07.011  1
2012 Ma X, Kovács M, Conti MA, Wang A, Zhang Y, Sellers JR, Adelstein RS. Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 4509-14. PMID 22393000 DOI: 10.1073/pnas.1116268109  1
2012 Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM. Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. Journal of Cell Science. 125: 2244-56. PMID 22328520 DOI: 10.1242/jcs.098806  1
2012 Zhang Y, Conti MA, Malide D, Dong F, Wang A, Shmist YA, Liu C, Zerfas P, Daniels MP, Chan CC, Kozin E, Kachar B, Kelley MJ, Kopp JB, Adelstein RS. Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood. 119: 238-50. PMID 21908426 DOI: 10.1182/blood-2011-06-358853  1
2011 Reyes A, He J, Mao CC, Bailey LJ, Di Re M, Sembongi H, Kazak L, Dzionek K, Holmes JB, Cluett TJ, Harbour ME, Fearnley IM, Crouch RJ, Conti MA, Adelstein RS, et al. Actin and myosin contribute to mammalian mitochondrial DNA maintenance. Nucleic Acids Research. 39: 5098-108. PMID 21398640 DOI: 10.1093/nar/gkr052  1
2010 Jacobelli J, Friedman RS, Conti MA, Lennon-Dumenil AM, Piel M, Sorensen CM, Adelstein RS, Krummel MF. Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nature Immunology. 11: 953-61. PMID 20835229 DOI: 10.1038/ni.1936  1
2010 Wang A, Ma X, Conti MA, Liu C, Kawamoto S, Adelstein RS. Nonmuscle myosin II isoform and domain specificity during early mouse development. Proceedings of the National Academy of Sciences of the United States of America. 107: 14645-50. PMID 20679233 DOI: 10.1073/pnas.1004023107  1
2010 Smutny M, Cox HL, Leerberg JM, Kovacs EM, Conti MA, Ferguson C, Hamilton NA, Parton RG, Adelstein RS, Yap AS. Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nature Cell Biology. 12: 696-702. PMID 20543839 DOI: 10.1038/ncb2072  1
2009 Vicente-Manzanares M, Ma X, Adelstein RS, Horwitz AR. Non-muscle myosin II takes centre stage in cell adhesion and migration. Nature Reviews. Molecular Cell Biology. 10: 778-90. PMID 19851336 DOI: 10.1038/nrm2786  1
2009 Ma X, Takeda K, Singh A, Yu ZX, Zerfas P, Blount A, Liu C, Towbin JA, Schneider MD, Adelstein RS, Wei Q. Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circulation Research. 105: 1102-9. PMID 19815823 DOI: 10.1161/CIRCRESAHA.109.200303  1
2009 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW. Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (Cambridge, England). 136: 1977-86. PMID 19439495 DOI: 10.1242/dev.030718  1
2009 Jana SS, Kim KY, Mao J, Kawamoto S, Sellers JR, Adelstein RS. An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. The Journal of Biological Chemistry. 284: 11563-71. PMID 19240025 DOI: 10.1074/jbc.M806574200  1
2009 Fischer RS, Gardel M, Ma X, Adelstein RS, Waterman CM. Local cortical tension by myosin II guides 3D endothelial cell branching. Current Biology : Cb. 19: 260-5. PMID 19185493 DOI: 10.1016/j.cub.2008.12.045  1
2008 Kim KY, Kawamoto S, Bao J, Sellers JR, Adelstein RS. The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility. Biochemical and Biophysical Research Communications. 369: 124-34. PMID 18060863 DOI: 10.1016/j.bbrc.2007.11.108  1
2007 Bao J, Ma X, Liu C, Adelstein RS. Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice. The Journal of Biological Chemistry. 282: 22102-11. PMID 17519229 DOI: 10.1074/jbc.M702731200  1
2006 Wu D, Asiedu M, Adelstein RS, Wei Q. A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle (Georgetown, Tex.). 5: 1234-9. PMID 16721066  1
2005 Kim KY, Kovács M, Kawamoto S, Sellers JR, Adelstein RS. Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. The Journal of Biological Chemistry. 280: 22769-75. PMID 15845534 DOI: 10.1074/jbc.M503488200  1
2005 Meshel AS, Wei Q, Adelstein RS, Sheetz MP. Basic mechanism of three-dimensional collagen fibre transport by fibroblasts. Nature Cell Biology. 7: 157-64. PMID 15654332 DOI: 10.1038/ncb1216  1
2004 Lo CM, Buxton DB, Chua GC, Dembo M, Adelstein RS, Wang YL. Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Molecular Biology of the Cell. 15: 982-9. PMID 14699073 DOI: 10.1091/mbc.E03-06-0359  1
2004 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS. Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. The Journal of Biological Chemistry. 279: 2800-8. PMID 14594953 DOI: 10.1074/jbc.M309981200  1
2003 Obungu VH, Burns AL, Agarwal SK, Chandrasekharapa SC, Adelstein RS, Marx SJ. Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain Oncogene. 22: 6347-6358. PMID 14508515 DOI: 10.1038/sj.onc.1206658  1
2003 Takeda K, Kishi H, Ma X, Yu ZX, Adelstein RS. Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis. Circulation Research. 93: 330-7. PMID 12893741 DOI: 10.1161/01.RES.0000089256.00309.CB  1
2002 Wei Q, Adelstein RS. Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling. Molecular Biology of the Cell. 13: 683-97. PMID 11854422 DOI: 10.1091/mbc.01-07-0358  1
2001 Bridgman PC, Dave S, Asnes CF, Tullio AN, Adelstein RS. Myosin IIB is required for growth cone motility. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6159-69. PMID 11487639  1
2001 Latham VM, Yu EH, Tullio AN, Adelstein RS, Singer RH. A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts. Current Biology : Cb. 11: 1010-6. PMID 11470405 DOI: 10.1016/S0960-9822(01)00291-3  1
2000 Wei Q, Adelstein RS. Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells Molecular Biology of the Cell. 11: 3617-3627. PMID 11029059  1
2000 Takeda K, Yu ZX, Qian S, Chin TK, Adelstein RS, Ferrans VJ. Nonmuscle myosin II localizes to the Z-lines and intercalated discs of cardiac muscle and to the Z-lines of skeletal muscle. Cell Motility and the Cytoskeleton. 46: 59-68. PMID 10842333 DOI: 10.1002/(SICI)1097-0169(200005)46:1<59::AID-CM6>3.0.CO;2-Q  1
2000 Uren D, Hwang HK, Hara Y, Takeda K, Kawamoto S, Tullio AN, Yu ZX, Ferrans VJ, Tresser N, Grinberg A, Preston YA, Adelstein RS. Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B-depleted mice. The Journal of Clinical Investigation. 105: 663-71. PMID 10712438 DOI: 10.1172/JCI8199  1
1997 Tullio AN, Accili D, Ferrans VJ, Yu ZX, Takeda K, Grinberg A, Westphal H, Preston YA, Adelstein RS. Nonmuscle myosin II-B is required for normal development of the mouse heart. Proceedings of the National Academy of Sciences of the United States of America. 94: 12407-12. PMID 9356462  1
1996 Adelstein RS, Collins FS, Hajra A, Kelley CA, Liu PP, Speck NA, Stacy T, Wang Q. The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 93: 15523. PMID 9340650  1
1996 Liu PP, Wijmenga C, Hajra A, Blake TB, Kelley CA, Adelstein RS, Bagg A, Rector J, Cotelingam J, Willman CL, Collins FS. Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells. Genes, Chromosomes & Cancer. 16: 77-87. PMID 8818654 DOI: 10.1002/(SICI)1098-2264(199606)16:2<77::AID-GCC1>3.0.CO;2-#  1
1996 Choi OH, Park CS, Itoh K, Adelstein RS, Beaven MA. Cloning of the cDNA encoding rat myosin heavy chain-A and evidence for the absence of myosin heavy chain-B in cultured rat mast (RBL-2H3) cells. Journal of Muscle Research and Cell Motility. 17: 69-77. PMID 8740433 DOI: 10.1007/BF00140325  1
1996 Kelley CA, Sellers JR, Gard DL, Bui D, Adelstein RS, Baines IC. Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities Journal of Cell Biology. 134: 675-687. PMID 8707847  1
1996 Pato MD, Sellers JR, Preston YA, Harvey EV, Adelstein RS. Baculovirus expression of chicken nonmuscle heavy meromyosin II-B: Characterization of alternatively spliced isoforms Journal of Biological Chemistry. 271: 2689-2695. PMID 8576242  1
1995 Rochlin MW, Itoh K, Adelstein RS, Bridgman PC. Localization of myosin II A and B isoforms in cultured neurons. Journal of Cell Science. 108: 3661-70. PMID 8719872  1
1995 Hajra A, Liu PP, Wang Q, Kelley CA, Stacy T, Adelstein RS, Speck NA, Collins FS. The leukemic core binding factor β-smooth muscle myosin heavy chain (CBFβ-SMMHC) chimeric protein requires both CBFβ and myosin heavy chain domains for transformation of NIH 3T3 cells Proceedings of the National Academy of Sciences of the United States of America. 92: 1926-1930. PMID 7892201 DOI: 10.1073/pnas.92.6.1926  1
1995 Kelley CA, Oberman F, Yisraeli JK, Adelstein RS. A Xenopus nonmuscle myosin heavy chain isoform is phosphorylated by cyclin-p34cdc2 kinase during meiosis Journal of Biological Chemistry. 270: 1395-1401. PMID 7836406  1
1995 Kelley CA, Adelstein RS. Characterization of myosin II isoforms containing insertions of amino acids in the flexible loop near the ATP-binding pocket Biophysical Journal. 68: 225s. PMID 7787079  1
1995 Phillips CL, Yamakawa K, Adelstein RS. Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies Journal of Muscle Research and Cell Motility. 16: 379-389. PMID 7499478 DOI: 10.1007/BF00114503  1
1994 Choi OH, Adelstein RS, Beaven MA. Secretion from rat basophilic RBL-2H3 cells is associated with diphosphorylation of myosin light chains by myosin light chain kinase as well as phosphorylation by protein kinase C. The Journal of Biological Chemistry. 269: 536-41. PMID 8276847  1
1994 Kelley CA, Adelstein RS. Characterization of isoform diversity in smooth muscle myosin heavy chains Canadian Journal of Physiology and Pharmacology. 72: 1351-1360. PMID 7767878  1
1994 Maupin P, Phillips CL, Adelstein RS, Pollard TD. Differential localization of myosin-II isozymes in human cultured cells and blood cells Journal of Cell Science. 107: 3077-3090. PMID 7699007  1
1993 Kelley CA, Takahashi M, Yu JH, Adelstein RS. An insert of seven amino acids confers functional differences between smooth muscle myosins from the intestines and vasculature Journal of Biological Chemistry. 268: 12848-12854. PMID 8509418  1
1993 Bhatia-Dey N, Adelstein RS, Dawid IB. Cloning of the cDNA encoding a myosin heavy chain B isoform of Xenopus nonmuscle myosin with an insert in the head region. Proceedings of the National Academy of Sciences of the United States of America. 90: 2856-9. PMID 8464900  1
1993 Moussavi RS, Kelley CA, Adelstein RS. Phosphorylation of vertebrate nonmuscle and smooth muscle myosin heavy chains and light chains Molecular and Cellular Biochemistry. 127: 219-227. PMID 7935353 DOI: 10.1007/BF01076773  1
1992 Kelley CA, Sellers JR, Goldsmith PK, Adelstein RS. Smooth muscle myosin is composed of homodimeric heavy chains Journal of Biological Chemistry. 267: 2127-2130. PMID 1733920  1
1992 Peleg I, Ludowyke RI, Beaven MA, Adelstein RS. The role of myosin phosphorylation in RBL-2H3 cell secretion. The Journal of Laboratory and Clinical Medicine. 120: 675-80. PMID 1385555  1
1989 Shohet RV, Conti MA, Kawamoto S, Preston YA, Brill DA, Adelstein RS. Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin Proceedings of the National Academy of Sciences of the United States of America. 86: 7726-7730. PMID 2813355  1
1988 Lamb NJ, Fernandez A, Conti MA, Adelstein R, Glass DB, Welch WJ, Feramisco JR. Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. The Journal of Cell Biology. 106: 1955-71. PMID 3290222  1
1987 Adelstein RS, Sellers JR. Effects of calcium on vascular smooth muscle contraction The American Journal of Cardiology. 59: B4-B10. PMID 3028118 DOI: 10.1016/0002-9149(87)90076-2  1
1986 Yisraeli J, Adelstein RS, Melloul D, Nudel U, Yaffe D, Cedar H. Muscle-specific activation of a methylated chimeric actin gene. Cell. 46: 409-16. PMID 3731275 DOI: 10.1016/0092-8674(86)90661-6  1
1986 Tobacman LS, Adelstein RS. Mechanism of regulation of cardiac actin-myosin subfragment 1 by troponin-tropomyosin Biochemistry. 25: 798-802. PMID 2938620  1
1985 Schneider MD, Sellers JR, Vahey M, Preston YA, Adelstein RS. Localization and topography of antigenic domains within the heavy chain of smooth muscle myosin Journal of Cell Biology. 101: 66-72. PMID 2409097 DOI: 10.1083/jcb.101.1.66  1
1984 Tobacman LS, Adelstein RS. Enzymatic comparisons between light chain isozymes of human cardiac myosin subfragment-1 Journal of Biological Chemistry. 259: 11226-11230. PMID 6147352  1
1981 De Lanerolle P, Adelstein RS, Feramisco JR, Burridge K. Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells Proceedings of the National Academy of Sciences of the United States of America. 78: 4738-4742. PMID 7029526  1
1976 Elzinga M, Maron BJ, Adelstein RS. Human heart and platelet actins are products of different genes Science. 191: 94-95. PMID 1246600  1
1975 Adelstein RS, Conti MA, Daniel JL, Anderson W. The interaction of platelet actin, myosin and myosin light chain kinase. Ciba Foundation Symposium. 35: 101-9. PMID 132340  1
1973 Elzinga M, Collins JH, Kuehl WM, Adelstein RS. Complete amino acid sequence of actin of rabbit skeletal muscle Proceedings of the National Academy of Sciences of the United States of America. 70: 2687-2691. PMID 4517681  1
1963 ADELSTEIN RS, GODFREY JE, KIELLEY WW. G-actin:preparation by gel filtration and evidence for a double stranded structure. Biochemical and Biophysical Research Communications. 12: 34-8. PMID 14011057  0.08
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