Ian S. Trowbridge - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
Area:
immunology
Website:
https://www.salk.edu/news-release/remembering-ian-trowbridge/

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2006 Jones DT, Trowbridge IS, Harris AL. Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate. Cancer Research. 66: 2749-56. PMID 16510596 DOI: 10.1158/0008-5472.Can-05-3857  0.334
1998 Gibson A, Futter CE, Maxwell S, Allchin EH, Shipman M, Kraehenbuhl JP, Domingo D, Odorizzi G, Trowbridge IS, Hopkins CR. Sorting mechanisms regulating membrane protein traffic in the apical transcytotic pathway of polarized MDCK cells. The Journal of Cell Biology. 143: 81-94. PMID 9763422 DOI: 10.1083/Jcb.143.1.81  0.388
1998 White S, Hatton SR, Siddiqui MA, Parker CD, Trowbridge IS, Collawn JF. Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras Journal of Biological Chemistry. 273: 14355-14362. PMID 9603944 DOI: 10.1074/Jbc.273.23.14355  0.363
1998 Futter CE, Gibson A, Allchin EH, Maxwell S, Ruddock LJ, Odorizzi G, Domingo D, Trowbridge IS, Hopkins CR. In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules. The Journal of Cell Biology. 141: 611-23. PMID 9566963 DOI: 10.1083/Jcb.141.3.611  0.361
1997 Odorizzi G, Trowbridge IS. Structural requirements for basolateral sorting of the human transferrin receptor in the biosynthetic and endocytic pathways of Madin-Darby canine kidney cells. The Journal of Cell Biology. 137: 1255-64. PMID 9182660 DOI: 10.1083/Jcb.137.6.1255  0.398
1997 Odorizzi G, Trowbridge IS. Structural requirements for major histocompatibility complex class II invariant chain trafficking in polarized Madin-Darby canine kidney cells. The Journal of Biological Chemistry. 272: 11757-62. PMID 9115230 DOI: 10.1074/Jbc.272.18.11757  0.363
1996 Odorizzi G, Pearse A, Domingo D, Trowbridge IS, Hopkins CR. Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism. The Journal of Cell Biology. 135: 139-52. PMID 8858169 DOI: 10.1083/Jcb.135.1.139  0.396
1996 Buchegger F, Trowbridge IS, Liu LFS, White S, Collawn JF. Functional analysis of human/chicken transferrin receptor chimeras indicates that the carboxy-terminal region is important for ligand binding European Journal of Biochemistry. 235: 9-17. PMID 8631371 DOI: 10.1111/J.1432-1033.1996.0009U.X  0.385
1995 Lai A, Sisodia SS, Trowbridge IS. Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. The Journal of Biological Chemistry. 270: 3565-73. PMID 7876092 DOI: 10.1074/Jbc.270.8.3565  0.347
1995 Perschl A, Lesley J, English N, Trowbridge I, Hyman R. Role of CD44 cytoplasmic domain in hyaluronan binding. European Journal of Immunology. 25: 495-501. PMID 7533087 DOI: 10.1002/Eji.1830250228  0.337
1994 Pacitti A, Stevis P, Evans M, Trowbridge I, Higgins TJ. High level expression and purification of the enzymatically active cytoplasmic region of human CD45 phosphatase from yeast. Biochimica Et Biophysica Acta. 1222: 277-86. PMID 8031864 DOI: 10.1016/0167-4889(94)90179-1  0.303
1994 Trowbridge IS, Thomas ML. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development Annual Review of Immunology. 12: 85-116. PMID 8011300 DOI: 10.1146/Annurev.Iy.12.040194.000505  0.399
1994 Odorizzi G, Trowbridge IS. Recombinant Rous sarcoma virus vectors for avian cells. Methods in Cell Biology. 43: 79-97. PMID 7529868 DOI: 10.1016/S0091-679X(08)60599-3  0.303
1992 Trowbridge IS, Collawn J, Jing S, White S, Esekogwu V, Stangel M. Structure-function analysis of the human transferrin receptor: effects of anti-receptor monoclonal antibodies on tumor growth. Current Studies in Hematology and Blood Transfusion. 139-47. PMID 1954762 DOI: 10.1159/000419352  0.376
1992 Trowbridge IS, Johnson P, Ostergaard H, Hole N. Structure and function of CD45: A leukocyte-specific protein tyrosine phosphatase Advances in Experimental Medicine and Biology. 323: 29-38. PMID 1485564 DOI: 10.1007/978-1-4615-3396-2_5  0.361
1992 Trowbridge IS, Collawn JF. Structural requirements for high efficiency endocytosis of the human transferrin receptor Journal of Inorganic Biochemistry. 47: 209-217. PMID 1431881 DOI: 10.1016/0162-0134(92)84066-V  0.382
1992 White S, Miller K, Hopkins C, Trowbridge IS. Monoclonal antibodies against defined epitopes of the human transferrin receptor cytoplasmic tail. Biochimica Et Biophysica Acta. 1136: 28-34. PMID 1379471 DOI: 10.1016/0167-4889(92)90081-L  0.401
1991 Miller K, Shipman M, Trowbridge IS, Hopkins CR. Transferrin receptors promote the formation of clathrin lattices Cell. 65: 621-632. PMID 1903330 DOI: 10.1016/0092-8674(91)90094-F  0.336
1991 Gerhardt EM, Chan LL, Jing S, Qi M, Trowbridge IS. The cDNA sequence and primary structure of the chicken transferrin receptor Gene. 102: 249-254. PMID 1874449 DOI: 10.1016/0378-1119(91)90085-P  0.353
1991 Trowbridge IS, Ostergaard HL, Johnson P. CD45: a leukocyte-specific member of the protein tyrosine phosphatase family Bba - Molecular Cell Research. 1095: 46-56. PMID 1834176 DOI: 10.1016/0167-4889(91)90043-W  0.308
1991 Luqman M, Johnson P, Trowbridge I, Bottomly K. Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 cell clones. European Journal of Immunology. 21: 17-22. PMID 1671357 DOI: 10.1002/Eji.1830210104  0.384
1991 Trowbridge IS. Endocytosis and signals for internalization. Current Opinion in Cell Biology. 3: 634-641. PMID 1663371 DOI: 10.1016/0955-0674(91)90034-V  0.305
1991 Collawn JF, Kuhn LA, Sue Liu LF, Tainer JA, Trowbridge IS. Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor Embo Journal. 10: 3247-3253. PMID 1655415 DOI: 10.1002/J.1460-2075.1991.Tb04888.X  0.368
1991 Ostergaard HL, Trowbridge IS. Negative regulation of CD45 protein tyrosine phosphatase activity by ionomycin in T cells Science. 253: 1423-1425. PMID 1654595 DOI: 10.1126/Science.1654595  0.351
1990 Jing S, Spencer T, Miller K, Hopkins C, Trowbridge IS. Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization. Journal of Cell Biology. 110: 283-294. PMID 2298808 DOI: 10.1083/Jcb.110.2.283  0.4
1990 Collawn JF, Stangel M, Kuhn LA, Esekogwu V, Jing S, Trowbridge IS, Tainer JA. Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis Cell. 63: 1061-1072. PMID 2257624 DOI: 10.1016/0092-8674(90)90509-D  0.342
1990 Ostergaard HL, Trowbridge IS. Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck Journal of Experimental Medicine. 172: 347-350. PMID 2141630 DOI: 10.1084/Jem.172.1.347  0.306
1989 Trowbridge IS. Cell surface receptors that serve to transport ligands Current Opinion in Cell Biology. 1: 186-191. PMID 2561068 DOI: 10.1016/0955-0674(89)90084-7  0.358
1989 Ostergaard HL, Shackelford DA, Hurley TR, Johnson P, Hyman R, Sefton BM, Trowbridge IS. Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proceedings of the National Academy of Sciences of the United States of America. 86: 8959-63. PMID 2530588 DOI: 10.1073/Pnas.86.22.8959  0.345
1989 Birkeland ML, Johnson P, Trowbridge IS, Puré E. Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation Proceedings of the National Academy of Sciences of the United States of America. 86: 6734-6738. PMID 2528147 DOI: 10.1073/Pnas.86.17.6734  0.41
1989 Johnson P, Greenbaum L, Bottomly K, Trowbridge IS. Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. The Journal of Experimental Medicine. 169: 1179-84. PMID 2466938 DOI: 10.1084/Jem.169.3.1179  0.384
1989 Trowbridge I. Cell surface antigen Thy-1. Immunology, neurology, and therapeutic applications:Edited by A. E. Reif and M. Schlesinger. New York: Marcel Dekker, Inc. (1989). 618 pp. $165.00 Cell. 58: 613-614. DOI: 10.1016/0092-8674(89)90094-9  0.308
1988 Omary MB, Trowbridge IS, Letarte M, Kagnoff MF, Isacke CM. Structural heterogeneity of human Pgp-1 and its relationship with p85. Immunogenetics. 27: 460-4. PMID 3286493 DOI: 10.1007/Bf00364434  0.314
1987 Trowbridge IS, Lesley JF, Domingo D, Schulte R, Sauvage C, Rammensee HG. [24] Monoclonal antibodies to transferrin receptor and assay of their biological effects Methods in Enzymology. 147: 265-279. PMID 3670087 DOI: 10.1016/0076-6879(87)47117-6  0.437
1987 Trowbridge I. Interleukin-2 receptor proteins Nature. 327: 461-462. PMID 3108672 DOI: 10.1038/327461B0  0.324
1987 Thomas ML, Reynolds PJ, Chain A, Ben-Neriah Y, Trowbridge IS. B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 84: 5360-3. PMID 2955416 DOI: 10.1073/Pnas.84.15.5360  0.397
1987 Isacke CM, Trowbridge IS, Hunter T. Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies. Molecular and Cellular Biology. 6: 2745-51. PMID 2946941 DOI: 10.1128/Mcb.6.7.2745  0.342
1987 Ralph SJ, Thomas ML, Morton CC, Trowbridge IS. Structural variants of human T200 glycoprotein (leukocyte-common antigen). The Embo Journal. 6: 1251-1257. DOI: 10.1002/J.1460-2075.1987.Tb02361.X  0.372
1986 Isacke CM, Sauvage CA, Hyman R, Lesley J, Schulte R, Trowbridge IS. Identification and characterization of the human Pgp-1 glycoprotein Immunogenetics. 23: 326-332. PMID 3519447 DOI: 10.1007/Bf00398797  0.342
1986 Thesleff I, Partanen AM, Landschulz W, Trowbridge IS, Ekblom P. The role of transferrin receptors and iron delivery in mouse embryonic morphogenesis. Differentiation; Research in Biological Diversity. 30: 152-8. PMID 3007247 DOI: 10.1111/J.1432-0436.1985.Tb00526.X  0.42
1986 Lefrancois L, Thomas ML, Bevan MJ, Trowbridge IS. Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200 Journal of Experimental Medicine. 163: 1337-1342. PMID 2939172 DOI: 10.1084/Jem.163.5.1337  0.419
1985 Trowbridge IS, Lesley J, Trotter J, Hyman R. Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene Nature. 315: 666-669. PMID 3874369 DOI: 10.1038/315666A0  0.439
1985 Brenner MB, Trowbridge IS, Strominger JL. Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit. Cell. 40: 183-90. PMID 3871355 DOI: 10.1016/0092-8674(85)90321-6  0.4
1985 Domingo DL, Trowbridge IS. Transferrin receptor as a target for antibody-drug conjugates. Methods in Enzymology. 112: 238-247. PMID 2995760 DOI: 10.1016/S0076-6879(85)12020-3  0.409
1985 Trimmer JS, Trowbridge IS, Vacquier VD. Monoclonal antibody to a membrane glycoprotein inhibits the acrosome reaction and associated Ca2+ and H+ fluxes of sea urchin sperm. Cell. 40: 697-703. PMID 2982502 DOI: 10.1016/0092-8674(85)90218-1  0.326
1985 Rammensee HG, Lesley J, Trowbridge IS, Bevan MJ. Antibodies against the transferrin receptor block the induction of cytotoxic T lymphocytes. A new method for antigen-specific negative selection in vitro European Journal of Immunology. 15: 687-692. PMID 2408900 DOI: 10.1002/Eji.1830150709  0.459
1984 Hannum CH, Kappler JW, Trowbridge IS, Marrack P, Freed JH. Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor. Nature. 312: 65-7. PMID 6333642 DOI: 10.1038/312065A0  0.39
1984 Trowbridge IS, Newman RA, Domingo DL, Sauvage C. Transferrin receptors: Structure and function Biochemical Pharmacology. 33: 925-932. PMID 6324805 DOI: 10.1016/0006-2952(84)90447-7  0.321
1984 Lesley J, Domingo DL, Schulte R, Trowbridge IS. Effect of an anti-murine transferrin receptor-ricin A conjugate on bone marrow stem and progenitor cells treated in vitro Experimental Cell Research. 150: 400-407. PMID 6319165 DOI: 10.1016/0014-4827(84)90583-4  0.412
1984 Brenner MB, Trowbridge IS, McLean J, Strominger JL. Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor. The Journal of Experimental Medicine. 160: 541-51. PMID 6206180 DOI: 10.1084/Jem.160.2.541  0.488
1983 Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 35: 295-302. PMID 6605199 DOI: 10.1016/0092-8674(83)90232-5  0.436
1983 Newman R, Domingo D, Trotter J, Trowbridge I. Selection and properties of a mouse L-cell transformant expressing human transferrin receptor. Nature. 304: 643-645. PMID 6308476 DOI: 10.1038/304643A0  0.408
1983 FitzGerald DJ, Trowbridge IS, Pastan I, Willingham MC. Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus. Proceedings of the National Academy of Sciences of the United States of America. 80: 4134-8. PMID 6306663 DOI: 10.1073/Pnas.80.13.4134  0.414
1983 Watson AJ, DeMars R, Trowbridge IS, Bach FH. Detection of a novel human class II HLA antigen Nature. 304: 358-361. PMID 6192342 DOI: 10.1038/304358A0  0.369
1982 Hyman R, Trowbridge I, Stallings V, Trotter J. Revertant expressing a structural variant of t200 glycoprotein. Immunogenetics. 15: 413-420. PMID 7076288 DOI: 10.1007/Bf00364264  0.337
1982 Lesley J, Trowbridge IS. Genetic characterization of a polymorphic murine cell-surface glycoprotein Immunogenetics. 15: 313-320. PMID 7068175 DOI: 10.1007/Bf00364339  0.383
1982 Trowbridge IS, Lesley J, Schulte R, Hyman R, Trotter J. Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues Immunogenetics. 15: 299-312. PMID 7068174 DOI: 10.1007/Bf00364338  0.432
1982 Trowbridge IS, Lesley J, Schulte R. Murine cell surface transferrin receptor: Studies with an anti-receptor monoclonal antibody Journal of Cellular Physiology. 112: 403-410. PMID 6290505 DOI: 10.1002/Jcp.1041120314  0.468
1982 Trowbridge IS, Lopez F. Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proceedings of the National Academy of Sciences of the United States of America. 79: 1175-1179. PMID 6280171 DOI: 10.1073/Pnas.79.4.1175  0.43
1982 Bourguignon LYW, Balazovich K, Trowbridge IS, Hyman R. Immunoelectron microscopic localization of Thy-1 glycoprotein in wild type and Thy-1-negative lymphoma cells Cell Biology International Reports. 6: 745-755. PMID 6127167 DOI: 10.1016/0309-1651(82)90167-9  0.399
1981 Hyman R, Trowbridge I. Two complementation classes of T20 (Ly-5) glycoprotein-negative mutants Immunogenetics. 12: 511-523. PMID 7194313 DOI: 10.1007/Bf01561692  0.403
1981 Trowbridge IS, Domingo DL. Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells Nature. 294: 171-173. PMID 6272120 DOI: 10.1038/294171A0  0.443
1980 Omary MB, Trowbridge IS, Minowada J. Human cell-surface glycoprotein with unusual properties. Nature. 286: 888-891. PMID 7412870 DOI: 10.1038/286888A0  0.408
1980 Dennert G, Hyman R, Lesley J, Trowbridge IS. Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations Cellular Immunology. 53: 350-364. PMID 7407938 DOI: 10.1016/0008-8749(80)90335-4  0.448
1980 Hyman R, Trowbridge I, Cunningham K. Cell surface molecules of Friend erythroleukemias: Decrease in T200 glycoprotein expression after induction Journal of Cellular Physiology. 105: 469-482. PMID 7007399 DOI: 10.1002/Jcp.1041050311  0.443
1980 Omary MB, Trowbridge IS, Battifora HA. Human homologue of murine T200 glycoprotein. Journal of Experimental Medicine. 152: 842-852. PMID 6968338 DOI: 10.1084/Jem.152.4.842  0.392
1979 Chapman A, Trowbridge IS, Hyman R, Kornfeld S. Structure of the lipid-linked oligosaccharides that accumulate in class E Thy-1-negative mutant lymphomas. Cell. 17: 509-15. PMID 476829 DOI: 10.1016/0092-8674(79)90259-9  0.308
1979 Trowbridge IS, Hyman R. Abnormal lipid-linked oligosaccharides in class E thy-1-negative mutant lymphomas Cell. 17: 503-508. PMID 476828 DOI: 10.1016/0092-8674(79)90258-7  0.301
1979 Klein G, Hyman R, Trowbridge I. Correlated expression of a B-lymphocyte-specific glycoprotein (gp27/35) and the EBV receptor/C3 receptor complex in sublines from the same Burkitt lymphoma. International Journal of Cancer. 23: 37-41. PMID 215562 DOI: 10.1002/Ijc.2910230108  0.384
1978 Trowbridge IS, Hyman R, Mazauskas C. The synthesis and properties of T25 glycoprotein in thy-1-negative mutant lymphoma cells Cell. 14: 21-32. PMID 667934 DOI: 10.1016/0092-8674(78)90297-0  0.425
1978 Bourguignon LY, Hyman R, Trowbridge I, Singer SJ. Participation of histocompatibility antigens in capping of molecularly independent cell surface components by their specific antibodies. Proceedings of the National Academy of Sciences of the United States of America. 75: 2406-10. PMID 307764 DOI: 10.1073/Pnas.75.5.2406  0.44
1978 Bourguignon LY, Hyman R, Trowbridge I, Singer SJ. Localization of T25 glycoprotein in wild-type and Thy 1- mutant cells by immunofluorescence and immunoelectron microscopy. The Journal of Experimental Medicine. 147: 1348-54. PMID 77306 DOI: 10.1084/Jem.147.5.1348  0.403
1977 Trowbridge IS, Hyman R, Klein G. Human B cell line deficient in the expression of B cell-specific glycoproteins (GP 27,35) European Journal of Immunology. 7: 640-645. PMID 72671 DOI: 10.1002/Eji.1830070912  0.432
1976 Trowbridge IS, Hyman R, Mazauskas C. Surface molecules of cultured human lymphoid cells European Journal of Immunology. 6: 777-782. PMID 1087235 DOI: 10.1002/Eji.1830061105  0.414
1976 Trowbridge IS, Mazauskas C. Immunological properties of murine thymus-dependent lymphocyte surface glycoproteins. European Journal of Immunology. 6: 557-562. PMID 61878 DOI: 10.1002/Eji.1830060806  0.407
1975 Trowbridge IS, Hyman R. Thy-1 variants of mouse lymphomas: biochemical characterization of the genetic defect Cell. 6: 279-287. PMID 1052769 DOI: 10.1016/0092-8674(75)90179-8  0.385
1975 Trowbridge IS, Weissman IL, Bevan MJ. Mouse T-cell surface glycoprotein recognised by heterologous anti-thymocyte sera and its relationship to Thy-1 antigen. Nature. 256: 652-4. PMID 50563 DOI: 10.1038/256652A0  0.436
1975 Trowbridge IS, Ralph P, Bevan MJ. Differences in the surface proteins of mouse B and T cells. Proceedings of the National Academy of Sciences of the United States of America. 72: 157-61. PMID 47173 DOI: 10.1073/Pnas.72.1.157  0.418
1973 Trowbridge IS. Mitogenic Properties of Pea Lectin and Its Chemical Derivatives Proceedings of the National Academy of Sciences of the United States of America. 70: 3650-3654. PMID 4519653 DOI: 10.1073/Pnas.70.12.3650  0.326
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