Christopher T. Denny - Publications

Affiliations: 
Pediatrics UCLA Medical School, Los Angeles, CA, United States 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Denny CT. ChIP-ping away at EWS/ETS transcription networks. Cancer Cell. 26: 595-6. PMID 25517742 DOI: 10.1016/J.Ccell.2014.10.016  0.431
2014 Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Molecular Cancer Research : McR. 12: 1740-54. PMID 25092916 DOI: 10.1158/1541-7786.Mcr-14-0159  0.444
2013 Girgis MD, Federman N, Rochefort MM, McCabe KE, Wu AM, Nagy JO, Denny C, Tomlinson JS. An engineered anti-CA19-9 cys-diabody for positron emission tomography imaging of pancreatic cancer and targeting of polymerized liposomal nanoparticles. The Journal of Surgical Research. 185: 45-55. PMID 23827791 DOI: 10.1016/J.Jss.2013.05.095  0.313
2012 Anderson JL, Denny CT, Tap WD, Federman N. Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities. Pediatric Research. 72: 112-21. PMID 22546864 DOI: 10.1038/Pr.2012.54  0.432
2011 France KA, Anderson JL, Park A, Denny CT. Oncogenic fusion protein EWS/FLI1 down-regulates gene expression by both transcriptional and posttranscriptional mechanisms. The Journal of Biological Chemistry. 286: 22750-7. PMID 21531709 DOI: 10.1074/Jbc.M111.225433  0.546
2010 Ikeda AK, Judelson DR, Federman N, Glaser KB, Landaw EM, Denny CT, Sakamoto KM. ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways. Molecular Cancer Therapeutics. 9: 653-60. PMID 20197394 DOI: 10.1158/1535-7163.Mct-09-0812  0.392
2010 Girgis MD, McCabe K, Federman N, Wu AM, Denny C, Tomlinson JS. Targeting cancer with cys-diabody conjugated polymerized liposomal nanoparticles (PLNs) Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-A20  0.388
2008 Potikyan G, France KA, Carlson MR, Dong J, Nelson SF, Denny CT. Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 1291-302. PMID 18838963 DOI: 10.1038/Labinvest.2008.99  0.539
2008 Foote S, Denny C. Construction of YAC libraries with large inserts. Current Protocols in Human Genetics. Unit5.2. PMID 18428331 DOI: 10.1002/0471142905.Hg0502S31  0.306
2007 Potikyan G, Savene RO, Gaulden JM, France KA, Zhou Z, Kleinerman ES, Lessnick SL, Denny CT. EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins. Cancer Research. 67: 6675-84. PMID 17638877 DOI: 10.1158/0008-5472.Can-06-4140  0.657
2007 Ng KP, Potikyan G, Savene RO, Denny CT, Uversky VN, Lee KA. Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 479-84. PMID 17202261 DOI: 10.1073/Pnas.0607007104  0.428
2006 Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell. 9: 473-84. PMID 16766266 DOI: 10.1016/J.Ccr.2006.04.021  0.656
2006 Kim S, Denny CT, Wisdom R. Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins. Molecular and Cellular Biology. 26: 2467-78. PMID 16537893 DOI: 10.1128/Mcb.26.7.2467-2478.2006  0.42
2003 Deneen B, Hamidi H, Denny CT. Functional analysis of the EWS/ETS target gene uridine phosphorylase. Cancer Research. 63: 4268-74. PMID 12874036  0.418
2003 Deneen B, Welford SM, Ho T, Hernandez F, Kurland I, Denny CT. PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Molecular and Cellular Biology. 23: 3897-908. PMID 12748291 DOI: 10.1128/Mcb.23.11.3897-3908.2003  0.497
2002 Maris JM, Denny CT. Focus on embryonal malignancies. Cancer Cell. 2: 447-50. PMID 12498713 DOI: 10.1016/S1535-6108(02)00206-4  0.352
2001 Deneen B, Denny CT. Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation. Oncogene. 20: 6731-41. PMID 11709708 DOI: 10.1038/Sj.Onc.1204875  0.464
2001 Arvand A, Denny CT. Biology of EWS/ETS fusions in Ewing's family tumors Oncogene. 20: 5747-5754. PMID 11607824 DOI: 10.1038/Sj.Onc.1204598  0.502
2001 Denny C. Defining small round cell tumors of childhood: when is a rose really a rose. Journal of Pediatric Hematology Oncology. 23: 338-339. PMID 11563766 DOI: 10.1097/00043426-200108000-00003  0.373
2001 Welford SM, Hebert SP, Deneen B, Arvand A, Denny CT. DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis. The Journal of Biological Chemistry. 276: 41977-84. PMID 11553628 DOI: 10.1074/Jbc.M106757200  0.526
1999 Thompson AD, Teitell MA, Arvand A, Denny CT. Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells Oncogene. 18: 5506-5513. PMID 10523827 DOI: 10.1038/Sj.Onc.1202928  0.532
1999 Teitell M, Damore MA, Sulur GG, Turner DE, Stern MH, Said JW, Denny CT, Wall R. TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues Proceedings of the National Academy of Sciences of the United States of America. 96: 9809-9814. PMID 10449776 DOI: 10.1073/Pnas.96.17.9809  0.417
1998 Arvand A, Bastians H, Welford SM, Thompson AD, Ruderman JV, Denny CT. EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction. Oncogene. 17: 2039-45. PMID 9798675 DOI: 10.1038/Sj.Onc.1202129  0.348
1998 Welford SM, Gregg J, Chen E, Garrison D, Sorensen PH, Denny CT, Nelson SF. Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization Nucleic Acids Research. 26: 3059-3065. PMID 9611255 DOI: 10.1093/Nar/26.12.3059  0.415
1998 Chang DD, Park NH, Denny CT, Nelson SF, Pe M. Characterization of transformation related genes in oral cancer cells. Oncogene. 16: 1921-30. PMID 9591775 DOI: 10.1038/Sj.Onc.1201715  0.418
1997 May WA, Arvand A, Thompson AD, Braun BS, Wright M, Denny CT. EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic Nature Genetics. 17: 495-497. PMID 9398859 DOI: 10.1038/Ng1297-495  0.518
1996 Thompson AA, Omori SA, Gilly MJ, May W, Gordon MS, Wood WJ, Miyoshi E, Malone CS, Gimble J, Denny CT, Wall R. Alternatively spliced exons encode the tissue-specific 5' termini of leukocyte pp52 and stromal cell S37 mRNA isoforms. Genomics. 32: 352-7. PMID 8838798 DOI: 10.1006/Geno.1996.0129  0.386
1996 Denny CT. Gene rearrangements in Ewing's sarcoma. Cancer Investigation. 14: 83-8. PMID 8597892 DOI: 10.3109/07357909609018438  0.404
1995 Woodruff K, Wang N, May W, Adrone E, Denny C, Feig SA. The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia: a case report and review of the literature Cancer Genetics and Cytogenetics. 79: 25-31. PMID 7850747 DOI: 10.1016/0165-4608(94)00109-O  0.36
1995 Braun BS, Frieden R, Lessnick SL, May WA, Denny CT. Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Molecular and Cellular Biology. 15: 4623-30. PMID 7623854 DOI: 10.1128/Mcb.15.8.4623  0.667
1994 Sawyers CL, Denny CT. Chronic myelomonocytic leukemia: Tel-a-kinase what Ets all about. Cell. 77: 171-3. PMID 8168126 DOI: 10.1016/0092-8674(94)90307-7  0.404
1994 Sorensen PH, Lessnick SL, Lopez-Terrada D, Liu XF, Triche TJ, Denny CT. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nature Genetics. 6: 146-51. PMID 8162068 DOI: 10.1038/Ng0294-146  0.646
1993 May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, Zucman J, Thomas G, Denny CT. Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proceedings of the National Academy of Sciences of the United States of America. 90: 5752-6. PMID 8516324 DOI: 10.1073/Pnas.90.12.5752  0.674
1993 Wood WJ, Thompson AA, Korenberg J, Chen XN, May W, Wall R, Denny CT. Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics. 16: 187-92. PMID 8486355 DOI: 10.1006/Geno.1993.1157  0.384
1993 MacCollin M, Romano D, Budarf M, Denny C, Trofatter J, Menon A, Rouleau G, Fontaine B, Emanuel B, Gusella J. A set of STS assays targeting the chromosome 22 physical framework markers. Genomics. 15: 680-3. PMID 8468063 DOI: 10.1006/Geno.1993.1125  0.308
1993 May W, Korenberg JR, Chen XN, Lunsford L, Wood WJ, Thompson A, Wall R, Denny CT. Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family. Genomics. 15: 515-20. PMID 8468046 DOI: 10.1006/Geno.1993.1102  0.467
1993 Hromas R, May W, Denny C, Raskind W, Moore J, Maki RA, Beck E, Klemsz MJ. Human FLI-1 localizes to chromosome 11Q24 and has an aberrant transcript in neuroepithelioma. Biochimica Et Biophysica Acta. 1172: 155-8. PMID 8439553 DOI: 10.1016/0167-4781(93)90283-J  0.513
1993 May WA, Lessnick SL, Braun BS, Klemsz M, Lewis BC, Lunsford LB, Hromas R, Denny CT. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Molecular and Cellular Biology. 13: 7393-8. PMID 8246959 DOI: 10.1128/mcb.13.12.7393-7398.1993  0.699
1993 Lewis BC, Shah NP, Braun BS, Denny CT. Creation of a yeast artificial chromosome fragmentation vector based on lysine-2. Genetic Analysis, Techniques and Applications. 9: 86-90. PMID 1476795 DOI: 10.1016/1050-3862(92)90003-N  0.34
1991 Sawyers CL, Denny CT, Witte ON. Leukemia and the disruption of normal hematopoiesis Cell. 64: 337-350. PMID 1988151 DOI: 10.1016/0092-8674(91)90643-D  0.35
1991 Shah NP, Witte ON, Denny CT. Characterization of the BCR Promoter in Philadelphia Chromosome-Positive and -Negative Cell Lines Molecular and Cellular Biology. 11: 1854-1860. PMID 1900918 DOI: 10.1128/Mcb.11.4.1854  0.46
1990 Feingold JM, Ogden SD, Denny CT. Streamlined approach to creating yeast artificial chromosome libraries from specialized cell sources. Proceedings of the National Academy of Sciences of the United States of America. 87: 8637-41. PMID 2236075 DOI: 10.1073/Pnas.87.21.8637  0.399
1989 Denny CT, Shah NP, Ogden S, Willman C, McConnell T, Crist W, Carroll A, Witte ON. Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 86: 4254-8. PMID 2567002 DOI: 10.1073/Pnas.86.11.4254  0.345
1986 Denny CT, Hollis GF, Hecht F, Morgan R, Link MP, Smith SD, Kirsch IR. Common mechanism of chromosome inversion in B- and T-cell tumors: relevance to lymphoid development. Science (New York, N.Y.). 234: 197-200. PMID 3092355 DOI: 10.1126/science.3092355  0.378
1986 Denny CT, Hollis GF, Magrath IT, Kirsch IR. Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement. Molecular and Cellular Biology. 5: 3199-207. PMID 3018508 DOI: 10.1128/MCB.5.11.3199  0.322
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