Year |
Citation |
Score |
2020 |
Cheema MS, Good KV, Kim B, Soufari H, O'Sullivan C, Freeman ME, Stefanelli G, Casas CR, Zengeler KE, Kennedy AJ, Eirin Lopez JM, Howard PL, Zovkic IB, Shabanowitz J, Dryhurst DD, et al. Deciphering the Enigma of the Histone H2A.Z-1/H2A.Z-2 Isoforms: Novel Insights and Remaining Questions. Cells. 9. PMID 32397240 DOI: 10.3390/Cells9051167 |
0.723 |
|
2020 |
Poplawski SG, Garbett KA, McMahan RL, Kordasiewicz HB, Zhao H, Kennedy AJ, Goleva SB, Sanders TH, Motley ST, Swayze EE, Ecker DJ, Sweatt JD, Michael TP, Greer CB. An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement. Molecular Therapy. Nucleic Acids. 19: 1399-1412. PMID 32160709 DOI: 10.1016/J.Omtn.2020.01.027 |
0.593 |
|
2020 |
Phan BN, Bohlen JF, Davis BA, Ye Z, Chen HY, Mayfield B, Sripathy SR, Cerceo Page S, Campbell MN, Smith HL, Gallop D, Kim H, Thaxton CL, Simon JM, Burke EE, ... ... Kennedy AJ, et al. A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. Nature Neuroscience. PMID 32015540 DOI: 10.1038/S41593-019-0578-X |
0.504 |
|
2019 |
Chua GNL, Wassarman KL, Sun H, Alp JA, Jarczyk EI, Kuzio NJ, Bennett MJ, Malachowsky BG, Kruse M, Kennedy AJ. Cytosine-Based TET Enzyme Inhibitors. Acs Medicinal Chemistry Letters. 10: 180-185. PMID 30783500 DOI: 10.1021/Acsmedchemlett.8B00474 |
0.417 |
|
2018 |
Bales KL, Ianov L, Kennedy AJ, Sweatt JD, Gross AK. Autosomal dominant retinitis pigmentosa rhodopsin mutant Q344X drives specific alterations in chromatin complex gene transcription. Molecular Vision. 24: 153-164. PMID 29463953 |
0.462 |
|
2018 |
Stefanelli G, Azam AB, Walters BJ, Brimble MA, Gettens CP, Bouchard-Cannon P, Cheng HM, Davidoff AM, Narkaj K, Day JJ, Kennedy AJ, Zovkic IB. Learning and Age-Related Changes in Genome-wide H2A.Z Binding in the Mouse Hippocampus. Cell Reports. 22: 1124-1131. PMID 29386101 DOI: 10.1016/J.Celrep.2018.01.020 |
0.579 |
|
2017 |
Ianov L, De Both M, Chawla MK, Rani A, Kennedy AJ, Piras I, Day JJ, Siniard A, Kumar A, Sweatt JD, Barnes CA, Huentelman MJ, Foster TC. Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment. Frontiers in Aging Neuroscience. 9: 383. PMID 29276487 DOI: 10.3389/Fnagi.2017.00383 |
0.639 |
|
2017 |
Duke CG, Kennedy AJ, Gavin CF, Day JJ, Sweatt JD. Experience-dependent epigenomic reorganization in the hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 278-288. PMID 28620075 DOI: 10.1101/Lm.045112.117 |
0.718 |
|
2016 |
Kennedy AJ, Rahn EJ, Paulukaitis BS, Savell KE, Kordasiewicz HB, Wang J, Lewis JW, Posey J, Strange SK, Guzman-Karlsson MC, Phillips SE, Decker K, Motley ST, Swayze EE, Ecker DJ, et al. Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function. Cell Reports. PMID 27568567 DOI: 10.1016/J.Celrep.2016.08.004 |
0.754 |
|
2016 |
Houck JD, Dawson TK, Kennedy AJ, Kharel Y, Naimon ND, Field SD, Lynch KR, Macdonald TL. Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles. Acs Medicinal Chemistry Letters. 7: 487-92. PMID 27190598 DOI: 10.1021/Acsmedchemlett.6B00002 |
0.743 |
|
2016 |
Kennedy AJ, Bruce AM, Gineste C, Ballard TE, Olekhnovich IN, Macdonald TL, Hoffman PS. Synthesis and Antimicrobial Evaluation of Amixicile-Based Inhibitors of the Pyruvate: Ferredoxin Oxidoreductases of Anaerobic Bacteria and Epsilon Proteobacteria. Antimicrobial Agents and Chemotherapy. PMID 27090174 DOI: 10.1128/Aac.00670-16 |
0.572 |
|
2016 |
Kennedy AJ, Sweatt JD. Drugging the methylome: DNA methylation and memory. Critical Reviews in Biochemistry and Molecular Biology. 1-10. PMID 26915423 DOI: 10.3109/10409238.2016.1150958 |
0.583 |
|
2015 |
Kumar D, Aggarwal M, Kaas GA, Lewis J, Wang J, Ross DL, Zhong C, Kennedy A, Song H, Sweatt JD. Tet1 Oxidase Regulates Neuronal Gene Transcription, Active DNA Hydroxy-methylation, Object Location Memory, and Threat Recognition Memory. Neuroepigenetics. 4: 12-27. PMID 26644996 DOI: 10.1016/J.Nepig.2015.10.002 |
0.572 |
|
2015 |
Grubiši? V, Kennedy AJ, Sweatt JD, Parpura V. Pitt-Hopkins Mouse Model has Altered Particular Gastrointestinal Transits In Vivo. Autism Research : Official Journal of the International Society For Autism Research. PMID 25728630 DOI: 10.1002/Aur.1467 |
0.51 |
|
2015 |
Day JJ, Kennedy AJ, Sweatt JD. DNA methylation and its implications and accessibility for neuropsychiatric therapeutics. Annual Review of Pharmacology and Toxicology. 55: 591-611. PMID 25340930 DOI: 10.1146/annurev-pharmtox-010814-124527 |
0.649 |
|
2014 |
East JE, Kennedy AJ, Webb TJ. Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells. Medicinal Research Reviews. 34: 45-76. PMID 23239102 DOI: 10.1002/Med.21276 |
0.523 |
|
2012 |
Warren CA, van Opstal E, Ballard TE, Kennedy A, Wang X, Riggins M, Olekhnovich I, Warthan M, Kolling GL, Guerrant RL, Macdonald TL, Hoffman PS. Amixicile, a novel inhibitor of pyruvate: ferredoxin oxidoreductase, shows efficacy against Clostridium difficile in a mouse infection model. Antimicrobial Agents and Chemotherapy. 56: 4103-11. PMID 22585229 DOI: 10.1128/Aac.00360-12 |
0.544 |
|
2011 |
Kennedy AJ, Mathews TP, Kharel Y, Field SD, Moyer ML, East JE, Houck JD, Lynch KR, Macdonald TL. Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells. Journal of Medicinal Chemistry. 54: 3524-48. PMID 21495716 DOI: 10.1021/Jm2001053 |
0.7 |
|
2011 |
Kharel Y, Mathews TP, Kennedy AJ, Houck JD, Macdonald TL, Lynch KR. A rapid assay for assessment of sphingosine kinase inhibitors and substrates. Analytical Biochemistry. 411: 230-5. PMID 21216217 DOI: 10.1016/J.Ab.2011.01.003 |
0.697 |
|
2010 |
East JE, Kennedy AJ, Tomsig JL, De Leon AR, Lynch KR, Macdonald TL. Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX). Bioorganic & Medicinal Chemistry Letters. 20: 7132-6. PMID 20951039 DOI: 10.1016/J.Bmcl.2010.09.030 |
0.688 |
|
2010 |
Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. Journal of Medicinal Chemistry. 53: 2766-78. PMID 20205392 DOI: 10.1021/Jm901860H |
0.748 |
|
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