John N. Fain - Publications

1965-1985 Brown University, Providence, RI 
 1985- Biochemistry University of Tennessee Health Science Center, Memphis, TN, United States 

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Fain JN. Impact of glucocorticoid hormones on adipokine secretion and human adipose tissue metabolism. Hormone Molecular Biology and Clinical Investigation. 14: 25-32. PMID 25436717 DOI: 10.1515/Hmbci-2013-0008  0.379
2010 Fain JN, Cheema P, Tichansky DS, Madan AK. The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells. Journal of Inflammation (London, England). 7: 4. PMID 20145729 DOI: 10.1186/1476-9255-7-4  0.32
2010 Fain JN, Tagele BM, Cheema P, Madan AK, Tichansky DS. Release of 12 adipokines by adipose tissue, nonfat cells, and fat cells from obese women. Obesity (Silver Spring, Md.). 18: 890-6. PMID 19834460 DOI: 10.1038/Oby.2009.335  0.355
2008 Fain JN, Cheema P, Tichansky DS, Madan AK. Stimulation of human omental adipose tissue lipolysis by growth hormone plus dexamethasone. Molecular and Cellular Endocrinology. 295: 101-5. PMID 18640775 DOI: 10.1016/J.Mce.2008.05.014  0.382
2008 Fain JN, Buehrer B, Bahouth SW, Tichansky DS, Madan AK. Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue. Metabolism: Clinical and Experimental. 57: 1005-15. PMID 18555844 DOI: 10.1016/J.Metabol.2008.02.019  0.347
2008 Fain JN, Buehrer B, Tichansky DS, Madan AK. Regulation of adiponectin release and demonstration of adiponectin mRNA as well as release by the non-fat cells of human omental adipose tissue. International Journal of Obesity (2005). 32: 429-35. PMID 17895880 DOI: 10.1038/Sj.Ijo.0803745  0.355
2007 Fain JN, Nesbit AS, Sudlow FF, Cheema P, Peeples JM, Madan AK, Tichansky DS. Release in vitro of adipsin, vascular cell adhesion molecule 1, angiotensin 1-converting enzyme, and soluble tumor necrosis factor receptor 2 by human omental adipose tissue as well as by the nonfat cells and adipocytes. Metabolism: Clinical and Experimental. 56: 1583-90. PMID 17950111 DOI: 10.1016/J.Metabol.2007.06.028  0.334
2006 Fain JN. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitamins and Hormones. 74: 443-77. PMID 17027526 DOI: 10.1016/S0083-6729(06)74018-3  0.324
2005 Fain JN, Tichansky DS, Madan AK. Transforming growth factor beta1 release by human adipose tissue is enhanced in obesity. Metabolism: Clinical and Experimental. 54: 1546-51. PMID 16253647 DOI: 10.1016/J.Metabol.2005.05.024  0.319
2005 Fain JN, Madan AK. Insulin enhances vascular endothelial growth factor, interleukin-8, and plasminogen activator inhibitor 1 but not interleukin-6 release by human adipocytes. Metabolism: Clinical and Experimental. 54: 220-6. PMID 15690317 DOI: 10.1016/J.Metabol.2004.08.016  0.351
2004 Fain JN, Bahouth SW, Madan AK. TNFalpha release by the nonfat cells of human adipose tissue. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 28: 616-22. PMID 14770194 DOI: 10.1038/Sj.Ijo.0802594  0.34
2004 Fain JN, Madan AK, Hiler ML, Cheema P, Bahouth SW. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology. 145: 2273-82. PMID 14726444 DOI: 10.1210/En.2003-1336  0.316
2004 Fain JN, Bahouth SW, Madan AK. Haptoglobin release by human adipose tissue in primary culture. Journal of Lipid Research. 45: 536-42. PMID 14657203 DOI: 10.1194/Jlr.M300406-Jlr200  0.315
2003 Fain JN, Kanu A, Bahouth SW, Cowan GS, Lloyd Hiler M. Inhibition of leptin release by atrial natriuretic peptide (ANP) in human adipocytes. Biochemical Pharmacology. 65: 1883-8. PMID 12781340 DOI: 10.1016/S0006-2952(03)00154-0  0.387
2003 Kanu A, Fain JN, Bahouth SW, Cowan GS. Regulation of leptin release by insulin, glucocorticoids, G(i)-coupled receptor agonists, and pertussis toxin in adipocytes and adipose tissue explants from obese humans in primary culture. Metabolism: Clinical and Experimental. 52: 60-6. PMID 12524663 DOI: 10.1053/Meta.2003.50005  0.383
2003 Fain JN, Cheema PS, Bahouth SW, Lloyd Hiler M. Resistin release by human adipose tissue explants in primary culture. Biochemical and Biophysical Research Communications. 300: 674-8. PMID 12507502 DOI: 10.1016/S0006-291X(02)02864-4  0.352
2002 Fain JN, Kanu A, Bahouth SW, Cowan GS, Hiler ML, Leffler CW. Comparison of PGE2, prostacyclin and leptin release by human adipocytes versus explants of adipose tissue in primary culture. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 67: 467-73. PMID 12468269 DOI: 10.1054/Plef.2002.0430  0.36
2001 Fain JN, Leffler CW, Cowan GS, Buffington C, Pouncey L, Bahouth SW. Stimulation of leptin release by arachidonic acid and prostaglandin E(2) in adipose tissue from obese humans. Metabolism: Clinical and Experimental. 50: 921-8. PMID 11474480 DOI: 10.1053/Meta.2001.24927  0.374
2001 Fain JN, Del Mar NA, Meade CA, Reiner A, Goldowitz D. Abnormalities in the functioning of adipocytes from R6/2 mice that are transgenic for the Huntington's disease mutation. Human Molecular Genetics. 10: 145-52. PMID 11152662 DOI: 10.1093/Hmg/10.2.145  0.311
2000 Fain JN, Cowan GS, Buffington C, Andersen RN, Pouncey L, Bahouth SW. Regulation of leptin release by troglitazone in human adipose tissue. Metabolism: Clinical and Experimental. 49: 1485-90. PMID 11092516 DOI: 10.1053/Meta.2000.17675  0.36
2000 Fain JN, Leffler CW, Bahouth SW, Rice AM, Rivkees SA. Regulation of leptin release and lipolysis by PGE2 in rat adipose tissue. Prostaglandins & Other Lipid Mediators. 62: 343-50. PMID 11060898 DOI: 10.1016/S0090-6980(00)00088-5  0.425
2000 Fain JN, Bahouth SW. Regulation of leptin release by mammalian adipose tissue. Biochemical and Biophysical Research Communications. 274: 571-5. PMID 10924319 DOI: 10.1006/Bbrc.2000.3168  0.304
2000 Fain JN, Cowan GS, Buffington C, Li J, Pouncey L, Bahouth SW. Synergism between insulin and low concentrations of isoproterenol in the stimulation of leptin release by cultured human adipose tissue. Metabolism: Clinical and Experimental. 49: 804-9. PMID 10877211 DOI: 10.1053/Meta.2000.6244  0.395
2000 Rice AM, Fain JN, Rivkees SA. A1 adenosine receptor activation increases adipocyte leptin secretion. Endocrinology. 141: 1442-5. PMID 10746648 DOI: 10.1210/Endo.141.4.7423  0.409
2000 Fain JN, Bahouth SW. Regulation of lipolysis and leptin biosynthesis in rodent adipose tissue by growth hormone. Metabolism: Clinical and Experimental. 49: 239-44. PMID 10690952 DOI: 10.1016/S0026-0495(00)91481-1  0.423
1999 Fain JN, Ihle JH, Bahouth SW. Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice. Biochemical and Biophysical Research Communications. 263: 201-5. PMID 10486277 DOI: 10.1006/Bbrc.1999.1302  0.338
1998 Fain JN, Bahouth SW. Hormonal regulation of 18S RNA, leptin mRNA, and leptin release in adipocytes from hypothyroid rats. Metabolism: Clinical and Experimental. 47: 1455-61. PMID 9867073 DOI: 10.1016/S0026-0495(98)90069-5  0.374
1998 Fain JN, Bahouth SW. Stimulation of leptin release by actinomycin D in rat adipocytes. Biochemical Pharmacology. 55: 1309-14. PMID 9719487 DOI: 10.1016/S0006-2952(97)00638-2  0.35
1998 Fain JN, Bahouth SW. Effect of tri-iodothyronine on leptin release and leptin mRNA accumulation in rat adipose tissue. The Biochemical Journal. 332: 361-6. PMID 9601064 DOI: 10.1042/Bj3320361  0.378
1997 Fain JN, Coronel EC, Beauchamp MJ, Bahouth SW. Expression of leptin and beta 3-adrenergic receptors in rat adipose tissue in altered thyroid states. The Biochemical Journal. 322: 145-50. PMID 9078254 DOI: 10.1042/Bj3220145  0.344
1997 Fain JN, Gokmen-Polar Y, Bahouth SW. Wortmannin converts insulin but not oxytocin from an antilipolytic to a lipolytic agent in the presence of forskolin. Metabolism: Clinical and Experimental. 46: 62-6. PMID 9005971 DOI: 10.1016/S0026-0495(97)90169-4  0.347
1996 FAIN JN. EFFECT OF PUROMYCIN ON INCUBATED ADIPOSE TISSUE AND ITS RESPONSE TO DEXAMETHASONE, INSULIN, AND EPINEPHRINE. Biochimica Et Biophysica Acta. 84: 636-42. PMID 14266248 DOI: 10.1016/0926-6542(64)90023-X  0.383
1996 FAIN JN. COMPARISON OF GLUCOCORTICOID EFFECTS ON BROWN AND WHITE ADIPOSE TISSUE OF THE RAT. Endocrinology. 76: 549-52. PMID 14263299 DOI: 10.1210/Endo-76-3-549  0.346
1996 Myles ME, Fain JN. Effect of K+-induced depolarization on carbachol-stimulated inositol tetrakisphosphate accumulation in rat cerebrocortical slices. Biochimica Et Biophysica Acta. 1310: 19-24. PMID 9244170 DOI: 10.1016/0167-4889(95)00130-1  0.336
1996 Myles ME, Gokmen-Polar Y, Fain JN. Inhibition by NMDA of carbachol-stimulated inositol tetrakisphosphate accumulation in rat brain cortical slices. Neuropharmacology. 35: 415-21. PMID 8793903 DOI: 10.1016/0028-3908(96)00004-4  0.313
1996 Gokmen-Polar Y, Coronel EC, Bahouth SW, Fain JN. Insulin sensitizes beta-agonist and forskolin-stimulated lipolysis to inhibition by 2',5'-dideoxyadenosine. The American Journal of Physiology. 270: C562-9. PMID 8779920 DOI: 10.1152/Ajpcell.1996.270.2.C562  0.404
1995 Myles ME, Gokmen-Polar Y, Fain JN. Inhibition by veratridine of carbachol-stimulated inositol tetrakisphosphate accumulation in rat brain cortical slices. Neurochemical Research. 20: 1057-64. PMID 8570010 DOI: 10.1007/Bf00995560  0.424
1994 Myles ME, Fain JN. Carbachol, but not norepinephrine, NMDA, ionomycin, ouabain, or phorbol myristate acetate, increases inositol 1,3,4,5-tetrakisphosphate accumulation in rat brain cortical slices. Journal of Neurochemistry. 62: 2333-9. PMID 8189237 DOI: 10.1046/J.1471-4159.1994.62062333.X  0.405
1993 Kang ES, Betts D, Fain JN, Bahouth SW, Myers LK. Chronic exposure of rat fat cells to insulin enhances lipolysis and activation of partially purified hormone-sensitive lipase. Diabetes. 42: 1415-24. PMID 8397127 DOI: 10.2337/Diab.42.10.1415  0.398
1993 Claro E, Fain JN, Picatoste F. Noradrenaline stimulation unbalances the phosphoinositide cycle in rat cerebral cortical slices. Journal of Neurochemistry. 60: 2078-86. PMID 8388033 DOI: 10.1111/J.1471-4159.1993.Tb03492.X  0.415
1993 Sallés J, Wallace MA, Fain JN. Modulation of the phospholipase C activity in rat brain cortical membranes by simultaneous activation of distinct monoaminergic and cholinergic muscarinic receptors. Brain Research. Molecular Brain Research. 20: 111-7. PMID 8255172 DOI: 10.1016/0169-328X(93)90115-6  0.325
1993 Claro E, Picatoste F, Fain JN. [5] - Agonist Stimulation of Phosphoinositide Breakdown in Brain Membranes Methods in Neurosciences. 18: 38-48. DOI: 10.1016/B978-0-12-185285-6.50011-7  0.356
1993 Llahi S, Fain JN. Phosphatidylethanol Formation as Index of Phospholipase D Activity in Rat Brain Cortex Slices Methods in Neurosciences. 18: 30-37. DOI: 10.1016/B978-0-12-185285-6.50010-5  0.359
1992 Pittner RA, Fain JN. Ethanol is a potent stimulator of phosphatidylcholine breakdown in cultured rat hepatocytes. Biochimica Et Biophysica Acta. 1133: 316-20. PMID 1737064 DOI: 10.1016/0167-4889(92)90053-E  0.313
1992 Lee HM, Fain JN. Magnesium-dependent inhibition of agonist-stimulated phosphoinositide breakdown in rat cortical slices by excitatory amino acids. Journal of Neurochemistry. 59: 953-62. PMID 1322975 DOI: 10.1111/J.1471-4159.1992.Tb08336.X  0.37
1992 Claro E, Wallace MA, Fain JN. Concerted CMP-dependent [3H]inositol labeling of phosphoinositides and agonist activation of phospholipase C in rat brain cortical membranes. Journal of Neurochemistry. 58: 2155-61. PMID 1315377 DOI: 10.1111/J.1471-4159.1992.Tb10958.X  0.339
1992 Llahi S, Claro E, Fain JN. Quisqualate-stimulated phosphatidylinositol breakdown in rat cerebellar membranes. Journal of Neurochemistry. 58: 714-21. PMID 1309570 DOI: 10.1111/J.1471-4159.1992.Tb09776.X  0.369
1991 Carter HR, Fain JN. Muscarinic cholinergic stimulation of exogenous phosphatidylinositol hydrolysis is regulated by guanine nucleotides in rabbit brain cortical membranes. Journal of Neurochemistry. 56: 1616-22. PMID 2013756 DOI: 10.1111/J.1471-4159.1991.Tb02059.X  0.38
1991 Pittner RA, Fain JN. Activation of membrane protein kinase C by glucagon and Ca(2+)-mobilizing hormones in cultured rat hepatocytes. Role of phosphatidylinositol and phosphatidylcholine hydrolysis. The Biochemical Journal. 277: 371-8. PMID 1859365 DOI: 10.1042/Bj2770371  0.44
1991 Lee HM, Fain JN. Phorbol myristate acetate inhibition of phospholipase C activation by carbachol in slices of rat brain cortex is a delayed and indirect effect. Journal of Neurochemistry. 56: 1471-80. PMID 1849548 DOI: 10.1111/J.1471-4159.1991.Tb02040.X  0.391
1991 Wallace MA, Claro E, Carter HR, Fain JN. Phosphoinositide-specific phospholipase C activation in brain cortical membranes. Methods in Enzymology. 197: 183-90. PMID 1646929 DOI: 10.1016/0076-6879(91)97144-N  0.36
1990 Etindi R, Claro E, Fain JN. Lithium does not directly alter agonist-stimulated phosphoinositide-specific phospholipase C activation in rat brain cortical membranes. Molecular and Cellular Neurosciences. 1: 128-32. PMID 19912762 DOI: 10.1016/1044-7431(90)90016-W  0.362
1990 Pittner RA, Fain JN. Effects of insulin on inositol phosphate production in cultured rat hepatocytes. Biochimica Et Biophysica Acta. 1043: 218-24. PMID 2180488 DOI: 10.1016/0005-2760(90)90299-D  0.416
1990 Carter HR, Wallace MA, Fain JN. Activation of phospholipase C in rabbit brain membranes by carbachol in the presence of GTP gamma S; effects of biological detergents. Biochimica Et Biophysica Acta. 1054: 129-35. PMID 2166590 DOI: 10.1016/0167-4889(90)90214-X  0.313
1990 Carter HR, Wallace MA, Fain JN. Purification and characterization of PLC-beta m, a muscarinic cholinergic regulated phospholipase C from rabbit brain membrane. Biochimica Et Biophysica Acta. 1054: 119-28. PMID 2166589 DOI: 10.1016/0167-4889(90)90213-W  0.318
1990 Pittner RA, Fain JN. Sodium fluoride acts as a stimulator and inhibitor of phosphoinositide hydrolysis in permeabilized rat hepatocytes. Biochemical Society Transactions. 18: 480-1. PMID 2164997 DOI: 10.1042/Bst0180480  0.413
1990 Fain JN. Regulation of phosphoinositide-specific phospholipase C. Biochimica Et Biophysica Acta. 1053: 81-8. PMID 2163688 DOI: 10.1016/0167-4889(90)90029-D  0.318
1990 Claro E, Wallace MA, Fain JN. Dual effect of fluoride on phosphoinositide metabolism in rat brain cortex. Stimulation of phospholipase C and inhibition of polyphosphoinositide synthesis. The Biochemical Journal. 268: 733-7. PMID 2163621 DOI: 10.1042/Bj2680733  0.375
1990 Pittner RA, Fain JN. Vasopressin and norepinephrine stimulation of inositol phosphate accumulation in rat hepatocytes are modified differently by protein f1nase C and protein kinase A. Biochimica Et Biophysica Acta. 1043: 211-7. PMID 2107881 DOI: 10.1016/0005-2760(90)90298-C  0.418
1989 Etindi R, Fain JN. Insulin does not activate a phosphoinositide-specific phospholipase C in adipocytes. Molecular and Cellular Endocrinology. 67: 149-53. PMID 2558935 DOI: 10.1016/0303-7207(89)90204-9  0.339
1989 Claro E, Wallace MA, Lee HM, Fain JN. Carbachol in the presence of guanosine 5'-O-(3-thiotriphosphate) stimulates the breakdown of exogenous phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol by rat brain membranes. The Journal of Biological Chemistry. 264: 18288-95. PMID 2553703  0.305
1989 Lee HM, Fain JN. Regulation of oxytocin-induced phosphoinositide breakdown in adipocytes by adenosine, isoproterenol and insulin. Biochimica Et Biophysica Acta. 1013: 73-9. PMID 2551383 DOI: 10.1016/0167-4889(89)90130-4  0.442
1989 Pittner RA, Fain JN. Exposure of cultured hepatocytes to cyclic AMP enhances the vasopressin-mediated stimulation of inositol phosphate production. The Biochemical Journal. 257: 455-60. PMID 2539087 DOI: 10.1042/Bj2570455  0.394
1989 Pittner RA, Fain JN. Vasopressin transiently stimulates phospholipase C activity in cultured rat hepatocytes. Biochimica Et Biophysica Acta. 1010: 227-32. PMID 2536285 DOI: 10.1016/0167-4889(89)90165-1  0.388
1989 Pittner RA, Fain JN. Cyclic AMP enhances the vasopressin-mediated stimulation of inositol phosphate production in cultured rat hepatocytes Biochemical Society Transactions. 17: 90-91. DOI: 10.1042/Bst0170090  0.39
1988 Pittner RA, Fain JN. Insulin regulation of pyruvate kinase activity in cultured rat hepatocytes, in the presence of vasopressin, ionophore A23187 or 4 beta-phorbol 12 beta-myristate 13 alpha-acetate. The Biochemical Journal. 252: 717-21. PMID 3138974 DOI: 10.1042/Bj2520717  0.405
1988 Wojcikiewicz RJ, Fain JN. Polyamines inhibit phospholipase C-catalysed polyphosphoinositide hydrolysis. Studies with permeabilized GH3 cells. The Biochemical Journal. 255: 1015-21. PMID 2850792 DOI: 10.1042/Bj2551015  0.385
1988 Chiang TM, Wojcikiewicz RJ, Kang AH, Fain JN. Phosphorylation of the outer surface of platelets enhances the effects of collagen on aggregation, ATP release, calcium translocation and phosphoinositide hydrolysis. Thrombosis Research. 50: 719-31. PMID 2842886 DOI: 10.1016/0049-3848(88)90330-1  0.327
1988 Fain JN, Wallace MA, Wojcikiewicz RJ. Evidence for involvement of guanine nucleotide-binding regulatory proteins in the activation of phospholipases by hormones. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2569-74. PMID 2838362 DOI: 10.1096/Fasebj.2.10.2838362  0.363
1987 Fain JN, Litosch I. Hormonal activation of phosphoinositide breakdown in the presence of guanine nucleotides using a cell-free system from blowfly salivary glands. Methods in Enzymology. 141: 255-61. PMID 3037245 DOI: 10.1016/0076-6879(87)41073-2  0.723
1987 Fain JN. Activation of phosphoinositide specific phospholipase C by ligands in the presence of guanine nucleotides. Progress in Clinical and Biological Research. 249: 133-47. PMID 2823289 DOI: 10.1007/978-1-4684-5598-4_24  0.413
1987 Bojanic D, Wallace MA, Wojcikiewicz RJ, Fain JN. Guanine nucleotide and pyrophosphate activate exogenous phosphatidylinositol 4,5-bisphosphate hydrolysis in rat liver plasma membranes. Biochemical and Biophysical Research Communications. 147: 1088-94. PMID 2822038 DOI: 10.1016/S0006-291X(87)80182-1  0.401
1986 Wojcikiewicz RJ, Kent PA, Fain JN. Evidence that thyrotropin-releasing hormone-induced increases in GTPase activity and phosphoinositide metabolism in GH3 cells are mediated by a guanine nucleotide-binding protein other than Gs or Gi. Biochemical and Biophysical Research Communications. 138: 1383-9. PMID 3019344 DOI: 10.1016/S0006-291X(86)80436-3  0.388
1986 Litosch I, Fain JN. Regulation of phosphoinositide breakdown by guanine nucleotides Life Sciences. 39: 187-194. PMID 3016436 DOI: 10.1016/0024-3205(86)90529-1  0.717
1986 Mills I, García-Sainz JA, Fain JN. Pertussis toxin effects on adenylate cyclase activity, cyclic AMP accumulation and lipolysis in adipocytes from hypothyroid, euthyroid and hyperthyroid rats. Biochimica Et Biophysica Acta. 876: 619-30. PMID 3011106 DOI: 10.1016/0005-2760(86)90051-2  0.641
1985 Fain JN, Brindley DN, Pittner RA, Hawthorne JN. Stimulation of specific GTPase activity by vasopressin in isolated membranes from cultured rat hepatocytes Febs Letters. 192: 251-254. PMID 2998867 DOI: 10.1016/0014-5793(85)80118-6  0.419
1985 Brautigan DL, Randazzo P, Shriner C, Fain JN. Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells Lipids. 20: 492-495. PMID 2993780 DOI: 10.1007/Bf02534242  0.301
1985 Mills I, Fain JN. Pertussis toxin reversal of the antilipolytic action of insulin in rat adipocytes in the presence of forskolin does not involve cyclic AMP Biochemical and Biophysical Research Communications. 130: 1059-1065. PMID 2992496 DOI: 10.1016/0006-291X(85)91723-1  0.425
1985 Wallace MA, Fain JN. Analysis of hormone-induced changes of phosphoinositide metabolism in rat liver. Methods in Enzymology. 109: 469-79. PMID 2985928 DOI: 10.1016/0076-6879(85)09109-1  0.395
1985 Litosch I, Wallis C, Fain JN. 5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown Journal of Biological Chemistry. 260: 5464-5471. PMID 2985595  0.307
1984 Fain JN, Li SY, Litosch I, Wallace M. Synergistic activation of rat hepatocyte glycogen phosphorylase by A23187 and phorbol ester Biochemical and Biophysical Research Communications. 119: 88-94. PMID 6422939 DOI: 10.1016/0006-291X(84)91622-X  0.721
1984 Fain JN. Activation of plasma membrane phosphatidylinositol turnover by hormones Vitamins and Hormones. 41: 117-160. PMID 6397909 DOI: 10.1016/S0083-6729(08)60089-8  0.392
1984 Fain JN, Garcia-Sainz JA, Mills I, O'Donnell CJ. Activation of lipolysis and cyclic AMP accumulation in rabbit adipocytes by isoproterenol in the presence of forskolin or pertussis toxin. Biochimica Et Biophysica Acta. 798: 382-9. PMID 6324881 DOI: 10.1016/0304-4165(84)90113-2  0.566
1984 Litosch I, Lee HS, Fain JN. Phosphoinositide breakdown in blowfly salivary glands The American Journal of Physiology. 246: C141-147. PMID 6320653 DOI: 10.1152/Ajpcell.1984.246.1.C141  0.719
1984 Fain JN. Insulin secretion and action Metabolism. 33: 672-679. PMID 6146090 DOI: 10.1016/0026-0495(84)90069-6  0.407
1984 Fain JN, Mohell N, Wallace MA, Mills I. Metabolic effects of beta, alpha 1, and alpha 2 adrenoceptor activation on brown adipocytes isolated from the perirenal adipose tissue of fetal lambs. Metabolism: Clinical and Experimental. 33: 289-94. PMID 6141521 DOI: 10.1016/0026-0495(84)90052-0  0.416
1984 Marshall JM, Fain JN. Effects of forskolin and isoproterenol on cyclic AMP and tension in the myometrium European Journal of Pharmacology. 107: 25-34. PMID 6098482 DOI: 10.1016/0014-2999(84)90087-6  0.404
1984 Sundin U, Mills I, Fain JN. Thyroid-catecholamine interactions in isolated rat brown adipocytes Metabolism. 33: 1028-1033. PMID 6092828 DOI: 10.1016/0026-0495(84)90232-4  0.442
1984 Sadler K, Litosch I, Fain JN. Phosphoinositide synthesis and Ca2+ gating in blowfly salivary glands exposed to 5-hydroxytryptamine Biochemical Journal. 222: 327-334. PMID 6089767 DOI: 10.1042/Bj2220327  0.711
1984 Mills I, Moreno FJ, Fain JN. Forskolin inhibition of glucose metabolism in rat adipocytes independent of adenosine 3',5'-monophosphate accumulation and lipolysis Endocrinology. 115: 1066-1069. PMID 6086284 DOI: 10.1210/Endo-115-3-1066  0.364
1984 Mills I, O'Donnell CJ, Garcia-Sainz JA, Fain JN. Pertussis toxin corrects the defect in catecholamine or forskolin stimulation of cyclic AMP accumulation but not of lipolysis in adipocyte obtained from hyperthyroid rats Federation Proceedings. 43: no. 977.  0.572
1983 Fain JN, O'Donnell CJ, Mills I, Gárciá-Sáinz JA. Pertussis toxin reverses Gpp(NH)p inhibition of basal and forskolin activated adipocyte adenylate cyclase. Biochemical and Biophysical Research Communications. 116: 651-6. PMID 6686037 DOI: 10.1016/0006-291X(83)90574-0  0.638
1983 Moreno FJ, Mills I, García-Sáinz JA, Fain JN. Effects of pertussis toxin treatment on the metabolism of rat adipocytes. The Journal of Biological Chemistry. 258: 10938-43. PMID 6350297  0.605
1983 Sundin U, Fain JN. α2-Adrenergic inhibition of lipolysis and respiration in rat brown adipocytes Biochemical Pharmacology. 32: 3117-3120. PMID 6315018 DOI: 10.1016/0006-2952(83)90259-9  0.34
1983 Fain JN, Lin SH, Litosch I, Wallace M. III. Hormonal regulation of phosphatidylinositol breakdown Life Sciences. 32: 2055-2067. PMID 6302422 DOI: 10.1016/0024-3205(83)90093-0  0.73
1983 Lin SH, Wallace MA, Fain JN. Regulation of Ca2+-Mg2+-ATPase activity in hepatocyte plasma membranes by vasopressin and phenylephrine. Endocrinology. 113: 2268-75. PMID 6139276 DOI: 10.1210/Endo-113-6-2268  0.375
1982 Wallace MA, Randazzo P, Li SY, Fain JN. Direct stimulation of phosphatidylinositol degradation by addition of vasopressin to purified rat liver plasma membranes. Endocrinology. 111: 341-3. PMID 7084119 DOI: 10.1210/Endo-111-1-341  0.358
1982 Vileisis RA, Fain J, Oh W. Fatty acid synthesis in rat fetuses with intrauterine growth retardation. Metabolism-Clinical and Experimental. 31: 217-222. PMID 7078410 DOI: 10.1016/0026-0495(82)90056-7  0.305
1982 Litosch I, Hudson TH, Mills I, Fain JN. Forskolin an an activator of cyclic AMP accumulation and lipolysis in rat adipocytes Molecular Pharmacology. 22: 109-115. PMID 6289066  0.328
1982 Litosch I, Fradin M, Kasaian M, Lee HS, Fain JN. Regulation of adenylate cyclase and cyclic AMP phosphodiesterase by 5-hydroxytryptamine and calcium ions in blowfly salivary gland homogenates Biochemical Journal. 204: 153-159. PMID 6288011 DOI: 10.1042/Bj2040153  0.729
1982 Litosch I, Saito Y, Fain JN. Forskolin as an activator of cyclic AMP accumulation and secretion in blowfly salivary glands Biochemical Journal. 204: 147-151. PMID 6288010 DOI: 10.1042/Bj2040147  0.752
1982 Wallace MA, Agarwal KC, Garcia-Sainz JA, Fain JN. Alpha-adrenergic stimulation of phosphatidylinositol synthesis in human platelets as an alpha-2 effect secondary to platelet aggregation. Journal of Cellular Biochemistry. 18: 213-20. PMID 6121823 DOI: 10.1002/Jcb.1982.240180208  0.564
1982 Litosch I, Saito Y, Fain JN. 5-HT-stimulated arachidonic acid release from labeled phosphatidylinositol in blowfly salivary glands American Journal of Physiology - Cell Physiology. 12: C222-C226. DOI: 10.1152/Ajpcell.1982.243.5.C222  0.717
1981 Sue-Hwa Lin, Fain JN. Vasopressin and epinephrine stimulation of phosphatidylinositol breakdown in the plasma membrane of rat hepatocytes Life Sciences. 29: 1905-1912. PMID 7311724 DOI: 10.1016/0024-3205(81)90523-3  0.378
1981 Gar?ia-Sáinz JA, Litosch I, Hoffman BB, Lefkowitz RJ, Fain JN. Effect of thyroid status on alpha- and beta-catecholamine responsiveness of hamster adipocytes. Biochimica Et Biophysica Acta. 678: 334-41. PMID 6274417 DOI: 10.1016/0304-4165(81)90112-4  0.73
1981 Fain JN, Kabnick KS, Li SY. Effects of melittin on adipocyte metabolism unrelated to lysophospholipid accumulation Bba - General Subjects. 677: 274-279. PMID 6271252 DOI: 10.1016/0304-4165(81)90096-9  0.416
1981 Fain JN. Catecholamine-thyroid hormone interactions in liver and adipose tissue Life Sciences. 28: 1745-1754. PMID 6264260 DOI: 10.1016/0024-3205(81)90346-5  0.413
1981 Garcia-Sainz JA, Li SY, Fain JN. Alpha 2 adrenergic amines, adenosine and prostaglandins inhibit lipolysis and cyclic AMP accumulation in hamster adipocytes in the absence of extracellular sodium. Life Sciences. 28: 401-6. PMID 6261062 DOI: 10.1016/0024-3205(81)90085-0  0.6
1981 Burns TW, Langley PE, Terry BE, Bylund DB, Hoffman BB, Tharp MD, Lefkowitz RJ, García-Saínz JA, Fain JN. Pharmacological characterizations of adrenergic receptors in human adipocytes. The Journal of Clinical Investigation. 67: 467-75. PMID 6257762 DOI: 10.1172/Jci110055  0.585
1980 Tolbert ME, White AC, Aspry K, Cutts J, Fain JN. Stimulation by vasopressin and alpha-catecholamines of phosphatidylinositol formation in isolated rat liver parenchymal cells. The Journal of Biological Chemistry. 255: 1938-44. PMID 6766458  0.78
1980 Malbon CC, Gilman HR, Fain JN. Hormonal stimulation of cyclic AMP accumulation and glycogen phosphorylase activity in calcium-depleted hepatocytes from euthyroid and hypothyroid rats. The Biochemical Journal. 188: 593-9. PMID 6258557 DOI: 10.1042/Bj1880593  0.46
1980 García-Sáinz JA, Fain JN. Effect of adrenergic amines on phosphatidylinositol labeling and glycogen synthase activity in fat cells from euthyroid and hypothyroid rats. Molecular Pharmacology. 18: 72-7. PMID 6251360  0.586
1980 García-Sáinz JA, Fain JN. Effect of insulin, catecholamines and calcium ions on phospholipid metabolism in isolated white fat-cells. The Biochemical Journal. 186: 781-9. PMID 6249261 DOI: 10.1042/Bj1860781  0.633
1980 Fain JN, García-Sáinz JA. Role of phosphatidylinositol turnover in alpha 1 and of adenylate cyclase inhibition in alpha 2 effects of catecholamines. Life Sciences. 26: 1183-94. PMID 6248704 DOI: 10.1016/0024-3205(80)90062-4  0.59
1980 Garcia-Sáinz JA, Hasler AK, Fain JN. Alpha1-adrenergic activation of phosphatidylinositol labeling in isolated brown fat cells. Biochemical Pharmacology. 29: 3330-3. PMID 6111319 DOI: 10.1016/0006-2952(80)90313-5  0.585
1980 Hoffman BB, Michel T, Kilpatrick DM, Lefkowitz RJ, Tolbert ME, Gilman H, Fain JN. Agonist versus antagonist binding to alpha-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 77: 4569-73. PMID 6107908 DOI: 10.1073/Pnas.77.8.4569  0.759
1979 Shepherd RE, Moreno FJ, Cashore WJ, Fain JN. Effects of bilirubin on fat cell metabolism and lipolysis The American Journal of Physiology. 237: E504-508. PMID 517647 DOI: 10.1152/Ajpendo.1979.237.6.E504  0.441
1979 Fain JN, Berridge MJ. Relationship between phosphatidylinositol synthesis and recovery of 5-hydroxytryptamine-responsive Ca2+ flux in blowfly salivary glands. The Biochemical Journal. 180: 655-61. PMID 486139 DOI: 10.1042/Bj1800655  0.343
1979 Berridge MJ, Fain JN. Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine. The Biochemical Journal. 178: 59-69. PMID 435285 DOI: 10.1042/Bj1780059  0.339
1979 Fain JN, Malbon CC. Regulation of adenylate cyclase by adenosine Molecular and Cellular Biochemistry. 25: 143-169. PMID 225658 DOI: 10.1007/Bf00235364  0.395
1979 Fain JN, Li SY, Moreno FJ. Regulation of cyclic AMP metabolism and lipolysis in isolated rat fat cells by insulin, N6-(phenylisopropyl)adenosine and 2',5'-dideoxyadenosine Journal of Cyclic Nucleotide Research. 5: 189-196. PMID 225356  0.37
1979 Fain JN. Effect of lipolytic agents on adenosine and amp formation by fat cells Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 573: 510-520. PMID 223645 DOI: 10.1016/0005-2760(79)90225-X  0.434
1979 Moreno FJ, Shepherd RE, Fain JN. Effect of NAD, nicotinamide and nicotinic acid on cyclic AMP accumulation by fat cells Naunyn-Schmiedeberg's Archives of Pharmacology. 306: 179-183. PMID 221845 DOI: 10.1007/Bf00498989  0.426
1979 Fain JN, Berridge MJ. Relationship between hormonal activation of phosphatidylinositol hydrolysis, fluid secretion and calcium flux in the blowfly salivary gland. The Biochemical Journal. 178: 45-58. PMID 219851 DOI: 10.1042/Bj1780045  0.372
1979 Fain JN, Shepherd RE. Hormonal regulation of lipolysis: role of cyclic nucleotides, adenosine, and free fatty acids Advances in Experimental Medicine and Biology. 111: 43-77. PMID 218431 DOI: 10.1007/978-1-4757-0734-2_3  0.311
1978 Fain JN, Berridge MJ. Relationship between 5-hydroxytryptamine activation of phosphatidylinositol hydrolysis and calcium-ion entry in Calliphora salivary glands. Biochemical Society Transactions. 6: 1038-9. PMID 84769 DOI: 10.1042/Bst0061038  0.319
1977 Wieser PB, Zeiger MA, Fain JN. Effects of dimethylsulfoxide on cyclic AMP accumulation, lipolysis and glucose metabolism of fat cells Biochemical Pharmacology. 26: 775-778. PMID 193516 DOI: 10.1016/0006-2952(77)90223-4  0.456
1977 Birnbaum MJ, Fain JN. Activation of protein kinase and glycogen phosphorylase in isolated rat liver cells by glucagon and catecholamines Journal of Biological Chemistry. 252: 528-535. PMID 188818  0.305
1976 Birnbaum MJ, Schultz J, Fain JN. Hormone stimulated glycogenolysis in isolated goldfish hepatocytes American Journal of Physiology. 231: 191-197. PMID 183509 DOI: 10.1152/Ajplegacy.1976.231.1.191  0.619
1976 Pointer RH, Butcher FR, Fain JN. Studies on the role of cyclic guanosine 3':5' monophosphate and extracellular Ca2+ in the regulation of glycogenolysis in rat liver cells Journal of Biological Chemistry. 251: 2987-2992. PMID 178660  0.784
1976 Fain JN, Butcher FR. Cyclic guanosine 3':5' monophosphate and the regulation of lipolysis in rat fat cells Journal of Cyclic Nucleotide Research. 2: 71-78. PMID 177466  0.317
1975 Fain JN, Shepherd RE. Free fatty acids as feedback regulators of adenylate cyclase and cyclic 3':5' AMP accumulation in rat fat cells Journal of Biological Chemistry. 250: 6586-6592. PMID 169252  0.319
1975 Boyd TA, Wieser PB, Fain JN. Lipolysis and cyclic AMP accumulation in isolated fat cells from chicks General and Comparative Endocrinology. 26: 243-247. PMID 166018 DOI: 10.1016/0016-6480(75)90141-0  0.415
1975 Fain JN, Tolbert ME, Pointer RH, Butcher FR, Arnold A. Cyclic nucleotides and gluconeogenesis by rat liver cells. Metabolism: Clinical and Experimental. 24: 395-407. PMID 165360 DOI: 10.1016/0026-0495(75)90119-5  0.797
1975 Fain JN. Isolation of free brown and white fat cells. Methods in Enzymology. 35: 555-61. PMID 164607 DOI: 10.1016/0076-6879(75)35184-7  0.345
1975 Wieser PB, Fain JN. Insulin, prostaglandin E1, phenylisopropyladenosine and nicotinic acid as regulators of fat cell metabolism Endocrinology. 96: 1221-1225. PMID 164344 DOI: 10.1210/Endo-96-5-1221  0.387
1974 Fain JN, Pointer RH. Equal opportunity in biomedical research. Science (New York, N.Y.). 184: 413-4. PMID 17736504 DOI: 10.1126/Science.184.4135.413  0.696
1974 Wieser PB, Malgieri JA, Ward WF, Pointer RH, Fain JN. Effects of bovine growth hormone preparations, fragments of growth hormone and pituitary anti-insulin peptide on lipolysis and glucose metabolism of isolated fat cells and adipose tissue. Endocrinology. 95: 206-12. PMID 4835877 DOI: 10.1210/Endo-95-1-206  0.772
1974 Tolbert ME, Fain JN. Studies on the regulation of gluconeogenesis in isolated rat liver cells by epinephrine and glucagon. The Journal of Biological Chemistry. 249: 1162-6. PMID 4360679  0.766
1974 Wieser PB, Fain JN. Effects of adrenochrome and sodium perborate on isolated fat cell metabolism. Biochemical Pharmacology. 22: 3209-16. PMID 4358725 DOI: 10.1016/0006-2952(73)90095-6  0.401
1973 Czech MP, Fain JN. Antagonism of insulin action on glucose metabolism in white fat cells by dexamethasone. Endocrinology. 91: 518-22. PMID 4630099 DOI: 10.1210/Endo-91-2-518  0.564
1973 Pointer RH, Fain JN. Response of isolated white fat cells to anti-malarial drugs. Biochemical Pharmacology. 22: 3025-32. PMID 4357483 DOI: 10.1016/0006-2952(73)90189-5  0.779
1973 Fain JN, Psychoyos S, Czernik AJ, Frost S, Cash WD. Indomethacin, lipolysis and cyclic AMP accumulation in white fat cells Endocrinology. 93: 632-639. PMID 4352806 DOI: 10.1210/Endo-93-3-632  0.436
1973 Fain JN, Jacobs MD, Clement-Cormier YC. Interrelationship of cyclic AMP, lipolysis, and respiration in brown fat cells. The American Journal of Physiology. 224: 346-51. PMID 4346846 DOI: 10.1152/Ajplegacy.1973.224.2.346  0.36
1973 Tolbert ME, Butcher FR, Fain JN. Lack of correlation between catecholamine effects on cyclic adenosine 3':5'-monophosphate and gluconeogenesis in isolated rat liver cells. The Journal of Biological Chemistry. 248: 5686-92. PMID 4146753  0.772
1972 Fain JN, Rosenberg L. Antilipolytic action of insulin on fat cells. Diabetes. 21: 414-25. PMID 4340997 DOI: 10.2337/Diab.21.2.S414  0.423
1972 Fain JN, Rosenthal JW, Ward WF. Anti-lipolytic action of tolbutamide on brown fat cells. Endocrinology. 90: 52-9. PMID 4333014 DOI: 10.1210/Endo-90-1-52  0.427
1971 Czech MP, Fain JN. Dactinomycin inhibition of dexamethasone action on glucose metabolism in white fat cells. Biochimica Et Biophysica Acta. 230: 185-93. PMID 5573353 DOI: 10.1016/0304-4165(71)90203-0  0.571
1971 Fain JN, Rosenthal JW. Calorigenic action of triiodothyronine on white fat cells: effects of ouabain, oligomycin and catecholamines. Endocrinology. 89: 1205-11. PMID 4328934 DOI: 10.1210/Endo-89-5-1205  0.378
1971 Caldwell A, Fain JN. Triiodothyronine stimulation of cyclic adenosine 3',5'-monophosphate accumulation in fat cells. Endocrinology. 89: 1195-204. PMID 4328933 DOI: 10.1210/Endo-89-5-1195  0.415
1971 Fain JN, Dodd A, Novak L. Enzyme regulation in gluconeogenesis and lipogenesis. Relationship of protein synthesis and cyclic AMP to lipolytic action of growth hormone and glucocorticoids. Metabolism: Clinical and Experimental. 20: 109-18. PMID 4322085 DOI: 10.1016/0026-0495(71)90086-2  0.408
1971 Ward WF, Fain JN. The effects of dihydroergotamine upon adenyl cyclase and phosphodiesterase of rat fat cells Biochimica Et Biophysica Acta (Bba) - General Subjects. 237: 387-390. DOI: 10.1016/0304-4165(71)90335-7  0.455
1970 Czech MP, Fain JN. Insulin protection against fat cell receptor inactivation by trypsin. Endocrinology. 87: 191-4. PMID 5423323 DOI: 10.1210/Endo-87-1-191  0.561
1970 Fain JN. Effect of dibutyryl-3',5'-AMP, theophylline and norepinephrine on lipolytic action of growth hormone and glucocorticoid in white fat cells. Endocrinology. 82: 825-30. PMID 4316222 DOI: 10.1210/Endo-82-4-825  0.386
1970 Fain JN, Reed N. A mechanism for hormonal activation of lipolysis and respiration in free brown fat cells. Lipids. 5: 210-9. PMID 4314249 DOI: 10.1007/Bf02532471  0.397
1970 Fain JN, Loken SC, Czech MP. Oligomycin effects on lipolysis and the oxidative metabolism of brown fat cells. Biochimica Et Biophysica Acta. 197: 40-8. PMID 4312655 DOI: 10.1016/0005-2728(70)90006-X  0.582
1970 Loken SC, Fain JN. Failure of "bound insulin" to affect glucose metabolism of brown fat cells. Endocrinology. 86: 432-4. PMID 4311907 DOI: 10.1210/Endo-86-2-432  0.395
1969 Moskowitz J, Fain JN. Hormonal regulation of lipolysis and phosphorylase activity in human fat cells Journal of Clinical Investigation. 48: 1802-1808. PMID 4309801 DOI: 10.1172/Jci106146  0.465
1969 Fain JN. Studies on the role of RNA and protein synthesis in the lipolytic action of growth hormone in isolated fat cells. Advances in Enzyme Regulation. 5: 39-51. PMID 4301792 DOI: 10.1016/0065-2571(67)90007-6  0.359
1968 Fain JN. Stimulation by insulin and prostaglandin E1 of glucose metabolism and inhibition of lipolytic action of theophylline on fat cells in the absence of K+. Endocrinology. 83: 548-54. PMID 4175232 DOI: 10.1210/Endo-83-3-548  0.355
1967 Fain JN. Inhibition of lipolytic action of growth hormone and glucocorticoid by ultraviolet and x-radiation. Science (New York, N.Y.). 157: 1062-4. PMID 6036236 DOI: 10.1126/Science.157.3792.1062  0.378
1967 Fain JN. Adrenergic blockade of hormone-induced lipolysis in isolated fat cells. Annals of the New York Academy of Sciences. 139: 879-90. PMID 4292399 DOI: 10.1111/J.1749-6632.1967.Tb41257.X  0.376
1966 Galton DJ, Fain JN. Effects of prolonged incubation of isolated fat cells on their response to hormones stimulating lipolysis and glucose metabolism. The Biochemical Journal. 98: 557-61. PMID 4287408 DOI: 10.1042/Bj0980557  0.436
1966 Fain JN, Kovacev VP, Scow RO. Antilipolytic effect of insulin in isolated fat cells of the rat. Endocrinology. 78: 773-8. PMID 4285823 DOI: 10.1210/Endo-78-4-773  0.705
1966 Fain JN, Scow RO. Fatty acid synthesis in vivo in maternal and fetal tissues in the rat American Journal of Physiology-Legacy Content. 210: 19-25. DOI: 10.1152/Ajplegacy.1966.210.1.19  0.564
1965 Fain JN, Kovacev VP, Scow RO. Effect of growth hormone and dexamethasone on lipolysis and metabolism in isolated fat cells of the rat. The Journal of Biological Chemistry. 240: 3522-9. PMID 5835934  0.672
1965 Fain JN, Scow RO. Effect of hypophysectomy on lipid metabolism in pancreatectomized rats. Endocrinology. 77: 547-52. PMID 4284468 DOI: 10.1210/Endo-77-3-547  0.711
1965 FAIN JN, SCOW RO, URGOITI EJ, CHERNICK SS. Effect of Insulin on Fatty Acid Synthesisin Vivoandin Vitroin Pancreatectomized Rats Endocrinology. 77: 137-149. DOI: 10.1210/Endo-77-1-137  0.612
1962 FAIN JN. Effects of Dexamethasone and Growth Hormone on Fatty Acid Mobilization and Glucose Utilization in Adrenalectomized Rats Endocrinology. 71: 633-635. DOI: 10.1210/Endo-71-4-633  0.403
1962 FAIN JN, WILHELMI AE. Effects of Adrenalectomy, Hypophysectomy, Growth Hormone and Thyroxine on Fatty Acid Synthesisin Vivo1 Endocrinology. 71: 541-548. DOI: 10.1210/Endo-71-4-541  0.662
1962 Fain JN, Wilhelmi AE. Mitochondria, glycolytic systems, and the pasteur effect Biochimica Et Biophysica Acta. 64: 508-513. DOI: 10.1016/0006-3002(62)90309-8  0.672
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