Hiro Furukawa - Publications

Affiliations: 
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chou TH, Tajima N, Romero-Hernandez A, Furukawa H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell. PMID 32610085 DOI: 10.1016/j.cell.2020.05.052  0.36
2020 Perszyk RE, Myers SJ, Yuan H, Gibb AJ, Furukawa H, Sobolevsky AI, Traynelis SF. Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. PMID 32468591 DOI: 10.1113/JP278086  0.36
2020 Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins. Nature Structural & Molecular Biology. PMID 32066965 DOI: 10.1038/s41594-020-0396-6  0.36
2020 Michalski K, Syrjanen JL, Henze E, Kumpf J, Furukawa H, Kawate T. The cryo-EM structure of a pannexin 1 reveals unique motifs for ion selection and inhibition. Elife. 9. PMID 32048993 DOI: 10.7554/eLife.54670  0.36
2020 Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. Structure and assembly of calcium homeostasis modulator proteins. Nature Structural & Molecular Biology. PMID 31988524 DOI: 10.1038/s41594-019-0369-9  0.36
2020 Wang JX, Irvine MW, Burnell ES, Sapkota K, Thatcher RJ, Li M, Simorowski N, Volianskis A, Collingridge GL, Monaghan DT, Jane DE, Furukawa H. Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors. Nature Communications. 11: 423. PMID 31969570 DOI: 10.1038/s41467-020-14321-0  0.36
2019 Wang JX, Furukawa H. Dissecting diverse functions of NMDA receptors by structural biology. Current Opinion in Structural Biology. 54: 34-42. PMID 30703613 DOI: 10.1016/j.sbi.2018.12.009  0.36
2019 Regan MC, Zhu Z, Yuan H, Myers SJ, Menaldino DS, Tahirovic YA, Liotta DC, Traynelis SF, Furukawa H. Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors. Nature Communications. 10: 321. PMID 30659174 DOI: 10.1038/s41467-019-08291-1  0.36
2018 Wu Q, Regan M, Furukawa H, Jackson D. Role of heterotrimeric Gα proteins in maize development and enhancement of agronomic traits. Plos Genetics. 14: e1007374. PMID 29708966 DOI: 10.1371/journal.pgen.1007374  0.36
2018 Regan MC, Grant T, McDaniel MJ, Karakas E, Zhang J, Traynelis SF, Grigorieff N, Furukawa H. Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors. Neuron. PMID 29656875 DOI: 10.1016/j.neuron.2018.03.034  0.36
2017 Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia W, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron. 96: 242-244. PMID 28957672 DOI: 10.1016/j.neuron.2017.09.011  0.36
2017 Elegheert J, Cvetkovska V, Clayton AJ, Heroven C, Vennekens KM, Smukowski SN, Regan MC, Jia W, Smith AC, Furukawa H, Savas JN, de Wit J, Begbie J, Craig AM, Aricescu AR. Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins. Neuron. 95: 896-913.e10. PMID 28817804 DOI: 10.1016/j.neuron.2017.07.040  0.36
2017 Amin JB, Salussolia CL, Chan K, Regan MC, Dai J, Zhou HX, Furukawa H, Bowen ME, Wollmuth LP. Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors. The Journal of General Physiology. PMID 28507080 DOI: 10.1085/jgp.201711762  0.36
2017 Romero-Hernandez A, Furukawa H. Novel mode of antagonist binding in NMDA receptors revealed by the crystal structure of the GluN1-GluN2A ligand-binding domain complexed to NVP-AAM077. Molecular Pharmacology. PMID 28468946 DOI: 10.1124/mol.116.107912  0.36
2016 Romero-Hernandez A, Simorowski N, Karakas E, Furukawa H. Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain. Neuron. PMID 27916457 DOI: 10.1016/j.neuron.2016.11.006  0.36
2016 Regan MC, Furukawa H. Deeper Insights into the Allosteric Modulation of Ionotropic Glutamate Receptors. Neuron. 91: 1187-9. PMID 27657445 DOI: 10.1016/j.neuron.2016.09.013  0.36
2016 Malinauskas T, Furukawa H. Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry. Structure (London, England : 1993). 24: 1008-1009. PMID 27276428 DOI: 10.1016/j.str.2016.05.003  0.36
2016 Malinauskas T, Furukawa H. Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry. Structure (London, England : 1993). 24: 653-5. PMID 27145073 DOI: 10.1016/j.str.2016.04.004  0.36
2016 Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature. PMID 27135925 DOI: 10.1038/nature17679  0.36
2015 Regan MC, Romero-Hernandez A, Furukawa H. A structural biology perspective on NMDA receptor pharmacology and function. Current Opinion in Structural Biology. 33: 68-75. PMID 26282925 DOI: 10.1016/j.sbi.2015.07.012  0.36
2015 Karakas E, Regan MC, Furukawa H. Emerging structural insights into the function of ionotropic glutamate receptors. Trends in Biochemical Sciences. 40: 328-37. PMID 25941168 DOI: 10.1016/j.tibs.2015.04.002  0.36
2014 Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Molecular Pharmacology. 86: 548-60. PMID 25205677 DOI: 10.1124/mol.114.094516  0.36
2014 Karakas E, Furukawa H. Crystal structure of a heterotetrameric NMDA receptor ion channel. Science (New York, N.Y.). 344: 992-7. PMID 24876489 DOI: 10.1126/science.1251915  0.36
2014 Jespersen A, Tajima N, Fernandez-Cuervo G, Garnier-Amblard EC, Furukawa H. Structural insights into competitive antagonism in NMDA receptors. Neuron. 81: 366-78. PMID 24462099 DOI: 10.1016/j.neuron.2013.11.033  0.36
2013 Salussolia CL, Gan Q, Kazi R, Singh P, Allopenna J, Furukawa H, Wollmuth LP. A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9840-5. PMID 23739980 DOI: 10.1523/JNEUROSCI.2626-12.2013  0.36
2013 Hansen KB, Tajima N, Risgaard R, Perszyk RE, Jørgensen L, Vance KM, Ogden KK, Clausen RP, Furukawa H, Traynelis SF. Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors. Molecular Pharmacology. 84: 114-27. PMID 23625947 DOI: 10.1124/mol.113.085803  0.36
2012 Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Molecular Pharmacology. 82: 344-59. PMID 22596351 DOI: 10.1124/mol.112.078568  0.36
2012 Furukawa H. Structure and function of glutamate receptor amino terminal domains. The Journal of Physiology. 590: 63-72. PMID 22106178 DOI: 10.1113/jphysiol.2011.213850  0.36
2011 Karakas E, Simorowski N, Furukawa H. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature. 475: 249-53. PMID 21677647 DOI: 10.1038/nature10180  0.36
2011 Vance KM, Simorowski N, Traynelis SF, Furukawa H. Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors. Nature Communications. 2: 294. PMID 21522138 DOI: 10.1038/ncomms1295  0.36
2010 Hansen KB, Furukawa H, Traynelis SF. Control of assembly and function of glutamate receptors by the amino-terminal domain. Molecular Pharmacology. 78: 535-49. PMID 20660085 DOI: 10.1124/mol.110.067157  0.36
2009 Karakas E, Simorowski N, Furukawa H. Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. The Embo Journal. 28: 3910-20. PMID 19910922 DOI: 10.1038/emboj.2009.338  0.36
2007 Vásquez V, Cortes DM, Furukawa H, Perozo E. An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis. Biochemistry. 46: 6766-73. PMID 17500538 DOI: 10.1021/bi700322k  0.36
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