Michael K. Rosen - Publications

Affiliations: 
University of Texas Southwestern Medical Center, Dallas, TX, United States 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Yoshizawa T, Ali R, Jiou J, Fung HYJ, Burke KA, Kim SJ, Lin Y, Peeples WB, Saltzberg D, Soniat M, Baumhardt JM, Oldenbourg R, Sali A, Fawzi NL, Rosen MK, et al. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell. 173: 693-705.e22. PMID 29677513 DOI: 10.1016/j.cell.2018.03.003  0.32
2017 Chen B, Chou HT, Brautigam CA, Xing W, Yang S, Henry L, Doolittle LK, Walz T, Rosen MK. Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites. Elife. 6. PMID 28949297 DOI: 10.7554/eLife.29795  0.48
2016 Srinivasan N, Gordon O, Ahrens S, Franz A, Deddouche S, Chakravarty P, Phillips D, Yunus AA, Rosen MK, Valente RS, Teixeira L, Thompson B, Dionne MS, Wood W, Reis E Sousa C. Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster. Elife. 5. PMID 27871362 DOI: 10.7554/eLife.19662  0.48
2016 Pak CW, Kosno M, Holehouse AS, Padrick SB, Mittal A, Ali R, Yunus AA, Liu DR, Pappu RV, Rosen MK. Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein. Molecular Cell. 63: 72-85. PMID 27392146 DOI: 10.1016/j.molcel.2016.05.042  0.48
2016 Banani SF, Rice AM, Peeples WB, Lin Y, Jain S, Parker R, Rosen MK. Compositional Control of Phase-Separated Cellular Bodies. Cell. PMID 27374333 DOI: 10.1016/j.cell.2016.06.010  0.6
2016 Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD. Phase separation of signaling molecules promotes T cell receptor signal transduction. Science (New York, N.Y.). PMID 27056844 DOI: 10.1126/science.aad9964  0.6
2016 Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S. Correction: Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation. The Journal of Cell Biology. PMID 27002172 DOI: 10.1083/jcb.20150808103082016c  0.32
2016 Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S. Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation. The Journal of Cell Biology. PMID 26903538 DOI: 10.1083/jcb.201508081  0.6
2016 Clark L, Zahm JA, Ali R, Kukula M, Bian L, Patrie SM, Gardner KH, Rosen MK, Rosenbaum DM. Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris. Journal of Biomolecular Nmr. PMID 26894386 DOI: 10.1007/s10858-016-0016-2  0.6
2015 Banjade S, Wu Q, Mittal A, Peeples WB, Pappu RV, Rosen MK. Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck. Proceedings of the National Academy of Sciences of the United States of America. PMID 26553976 DOI: 10.1073/pnas.1508778112  0.6
2015 Clark L, Zahm JA, Ali R, Kukula M, Bian L, Patrie SM, Gardner KH, Rosen MK, Rosenbaum DM. Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris. Journal of Biomolecular Nmr. 62: 239-45. PMID 26025061 DOI: 10.1007/s10858-015-9939-2  0.6
2014 Chen XJ, Squarr AJ, Stephan R, Chen B, Higgins TE, Barry DJ, Martin MC, Rosen MK, Bogdan S, Way M. Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton. Developmental Cell. 30: 569-84. PMID 25203209 DOI: 10.1016/j.devcel.2014.08.001  0.6
2014 McGough IJ, Steinberg F, Jia D, Barbuti PA, McMillan KJ, Heesom KJ, Whone AL, Caldwell MA, Billadeau DD, Rosen MK, Cullen PJ. Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation. Current Biology : Cb. 24: 1670-6. PMID 24980502 DOI: 10.1016/j.cub.2014.06.024  0.6
2014 Dodd DA, Worth RG, Rosen MK, Grinstein S, van Oers NS, Hansen EJ. The Haemophilus ducreyi LspA1 protein inhibits phagocytosis by using a new mechanism involving activation of C-terminal Src kinase. Mbio. 5: e01178-14. PMID 24902122 DOI: 10.1128/mBio.01178-14  0.6
2014 Chen B, Padrick SB, Henry L, Rosen MK. Biochemical reconstitution of the WAVE regulatory complex. Methods in Enzymology. 540: 55-72. PMID 24630101 DOI: 10.1016/B978-0-12-397924-7.00004-2  0.48
2014 Chia PH, Chen B, Li P, Rosen MK, Shen K. Local F-actin network links synapse formation and axon branching. Cell. 156: 208-20. PMID 24439377 DOI: 10.1016/j.cell.2013.12.009  0.6
2014 Chen B, Brinkmann K, Chen Z, Pak CW, Liao Y, Shi S, Henry L, Grishin NV, Bogdan S, Rosen MK. The WAVE regulatory complex links diverse receptors to the actin cytoskeleton. Cell. 156: 195-207. PMID 24439376 DOI: 10.1016/j.cell.2013.11.048  0.6
2013 Zahm JA, Padrick SB, Chen Z, Pak CW, Yunus AA, Henry L, Tomchick DR, Chen Z, Rosen MK. The bacterial effector VopL organizes actin into filament-like structures. Cell. 155: 423-34. PMID 24120140 DOI: 10.1016/j.cell.2013.09.019  0.48
2013 Smith BA, Padrick SB, Doolittle LK, Daugherty-Clarke K, Corrêa IR, Xu MQ, Goode BL, Rosen MK, Gelles J. Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation. Elife. 2: e01008. PMID 24015360 DOI: 10.7554/eLife.01008  0.6
2013 Doolittle LK, Rosen MK, Padrick SB. Measurement and analysis of in vitro actin polymerization. Methods in Molecular Biology (Clifton, N.J.). 1046: 273-93. PMID 23868594 DOI: 10.1007/978-1-62703-538-5_16  0.48
2013 Doolittle LK, Rosen MK, Padrick SB. Purification of Arp2/3 complex from Saccharomyces cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 1046: 251-71. PMID 23868593 DOI: 10.1007/978-1-62703-538-5_15  0.48
2013 Doolittle LK, Rosen MK, Padrick SB. Purification of native Arp2/3 complex from bovine thymus. Methods in Molecular Biology (Clifton, N.J.). 1046: 231-50. PMID 23868592 DOI: 10.1007/978-1-62703-538-5_14  0.48
2013 Hao YH, Doyle JM, Ramanathan S, Gomez TS, Jia D, Xu M, Chen ZJ, Billadeau DD, Rosen MK, Potts PR. Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination. Cell. 152: 1051-64. PMID 23452853 DOI: 10.1016/j.cell.2013.01.051  0.6
2012 Rizo J, Rosen MK, Gardner KH. Enlightening molecular mechanisms through study of protein interactions Journal of Molecular Cell Biology. 4: 270-283. PMID 22735643 DOI: 10.1093/jmcb/mjs036  0.6
2012 Jia D, Gomez TS, Billadeau DD, Rosen MK. Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer. Molecular Biology of the Cell. 23: 2352-61. PMID 22513087 DOI: 10.1091/mbc.E11-12-1059  0.6
2012 Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK. Phase transitions in the assembly of multivalent signalling proteins. Nature. 483: 336-40. PMID 22398450 DOI: 10.1038/nature10879  0.6
2011 Yu B, Cheng HC, Brautigam CA, Tomchick DR, Rosen MK. Mechanism of actin filament nucleation by the bacterial effector VopL. Nature Structural & Molecular Biology. 18: 1068-74. PMID 21873984 DOI: 10.1038/nsmb.2110  0.48
2011 Padrick SB, Doolittle LK, Brautigam CA, King DS, Rosen MK. Arp2/3 complex is bound and activated by two WASP proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: E472-9. PMID 21676863 DOI: 10.1073/pnas.1100236108  0.48
2010 Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK. Structure and control of the actin regulatory WAVE complex. Nature. 468: 533-8. PMID 21107423 DOI: 10.1038/nature09623  0.6
2010 Otomo T, Tomchick DR, Otomo C, Machius M, Rosen MK. Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One. 5. PMID 20927343 DOI: 10.1371/journal.pone.0012896  0.48
2010 Padrick SB, Deka RK, Chuang JL, Wynn RM, Chuang DT, Norgard MV, Rosen MK, Brautigam CA. Determination of protein complex stoichiometry through multisignal sedimentation velocity experiments. Analytical Biochemistry. 407: 89-103. PMID 20667444 DOI: 10.1016/j.ab.2010.07.017  0.6
2010 Strickland D, Yao X, Gawlak G, Rosen MK, Gardner KH, Sosnick TR. Rationally improving LOV domain-based photoswitches. Nature Methods. 7: 623-6. PMID 20562867 DOI: 10.1038/nmeth.1473  0.6
2010 Padrick SB, Rosen MK. Physical mechanisms of signal integration by WASP family proteins. Annual Review of Biochemistry. 79: 707-35. PMID 20533885 DOI: 10.1146/annurev.biochem.77.060407.135452  0.48
2010 Westerberg LS, Meelu P, Baptista M, Eston MA, Adamovich DA, Cotta-de-Almeida V, Seed B, Rosen MK, Vandenberghe P, Thrasher AJ, Klein C, Alt FW, Snapper SB. Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. The Journal of Experimental Medicine. 207: 1145-52. PMID 20513746 DOI: 10.1084/jem.20091245  0.6
2010 Jia D, Gomez TS, Metlagel Z, Umetani J, Otwinowski Z, Rosen MK, Billadeau DD. WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes. Proceedings of the National Academy of Sciences of the United States of America. 107: 10442-7. PMID 20498093 DOI: 10.1073/pnas.0913293107  0.6
2010 Yu B, Martins IR, Li P, Amarasinghe GK, Umetani J, Fernandez-Zapico ME, Billadeau DD, Machius M, Tomchick DR, Rosen MK. Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1. Cell. 140: 246-56. PMID 20141838 DOI: 10.1016/j.cell.2009.12.033  0.6
2009 Vingadassalom D, Kazlauskas A, Skehan B, Cheng HC, Magoun L, Robbins D, Rosen MK, Saksela K, Leong JM. Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proceedings of the National Academy of Sciences of the United States of America. 106: 6754-9. PMID 19366662 DOI: 10.1073/pnas.0809131106  0.6
2009 Ismail AM, Padrick SB, Chen B, Umetani J, Rosen MK. The WAVE regulatory complex is inhibited. Nature Structural & Molecular Biology. 16: 561-3. PMID 19363480 DOI: 10.1038/nsmb.1587  0.48
2009 Beel K, Cotter MM, Blatny J, Bond J, Lucas G, Green F, Vanduppen V, Leung DW, Rooney S, Smith OP, Rosen MK, Vandenberghe P. A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene British Journal of Haematology. 144: 120-126. PMID 19006568 DOI: 10.1111/j.1365-2141.2008.07416.x  0.6
2008 Padrick SB, Cheng HC, Ismail AM, Panchal SC, Doolittle LK, Kim S, Skehan BM, Umetani J, Brautigam CA, Leong JM, Rosen MK. Hierarchical regulation of WASP/WAVE proteins. Molecular Cell. 32: 426-38. PMID 18995840 DOI: 10.1016/j.molcel.2008.10.012  0.48
2008 Campellone KG, Cheng HC, Robbins D, Siripala AD, McGhie EJ, Hayward RD, Welch MD, Rosen MK, Koronakis V, Leong JM. Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly. Plos Pathogens. 4: e1000191. PMID 18974829 DOI: 10.1371/journal.ppat.1000191  0.6
2008 Leung DW, Otomo C, Chory J, Rosen MK. Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway Proceedings of the National Academy of Sciences of the United States of America. 105: 12797-12802. PMID 18728185 DOI: 10.1073/pnas.0801232105  0.6
2008 Yao X, Rosen MK, Gardner KH. Estimation of the available free energy in a LOV2-Jα photoswitch Nature Chemical Biology. 4: 491-497. PMID 18604202 DOI: 10.1038/nchembio.99  0.6
2008 Li P, Martins IR, Amarasinghe GK, Rosen MK. Internal dynamics control activation and activity of the autoinhibited Vav DH domain. Nature Structural & Molecular Biology. 15: 613-8. PMID 18488041 DOI: 10.1038/nsmb.1428  0.6
2007 Liverman ADB, Cheng HC, Trosky JE, Leung DW, Yarbrough ML, Burdette DL, Rosen MK, Orth K. Arp2/3-independent assembly of actin by Vibrio type III effector VopL Proceedings of the National Academy of Sciences of the United States of America. 104: 17117-17122. PMID 17942696 DOI: 10.1073/pnas.0703196104  0.6
2007 Ferguson AD, Amezcua CA, Halabi NM, Chelliah Y, Rosen MK, Ranganathan R, Deisenhofer J. Signal transduction pathway of TonB-dependent transporters. Proceedings of the National Academy of Sciences of the United States of America. 104: 513-8. PMID 17197416 DOI: 10.1073/pnas.0609887104  0.6
2006 Leung DW, Morgan DM, Rosen MK. Biochemical properties and inhibitors of (N-)WASP Methods in Enzymology. 406: 281-296. PMID 16472665 DOI: 10.1016/S0076-6879(06)06021-6  0.6
2005 Amarasinghe GK, Rosen MK. Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. Biochemistry. 44: 15257-68. PMID 16285729 DOI: 10.1021/bi051126h  0.6
2005 Kreishman-Deitrick M, Goley ED, Burdine L, Denison C, Egile C, Li R, Murali N, Kodadek TJ, Welch MD, Rosen MK. NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein. Biochemistry. 44: 15247-56. PMID 16285728 DOI: 10.1021/bi051065n  0.6
2005 Shemesh T, Otomo T, Rosen MK, Bershadsky AD, Kozlov MM. A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox. The Journal of Cell Biology. 170: 889-93. PMID 16157699 DOI: 10.1083/jcb.200504156  0.6
2005 Otomo T, Otomo C, Tomchick DR, Machius M, Rosen MK. Structural basis of Rho GTPase-mediated activation of the formin mDia1. Molecular Cell. 18: 273-81. PMID 15866170 DOI: 10.1016/j.molcel.2005.04.002  0.48
2005 Leung DW, Rosen MK. The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein Proceedings of the National Academy of Sciences of the United States of America. 102: 5685-5690. PMID 15821030 DOI: 10.1073/pnas.0406472102  0.6
2005 Otomo T, Tomchick DR, Otomo C, Panchal SC, Machius M, Rosen MK. Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain. Nature. 433: 488-94. PMID 15635372 DOI: 10.1038/nature03251  0.48
2004 Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK. Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nature Structural & Molecular Biology. 11: 747-55. PMID 15235593 DOI: 10.1038/nsmb796  0.6
2003 Labno CM, Lewis CM, You D, Leung DW, Takesono A, Kamberos N, Seth A, Finkelstein LD, Rosen MK, Schwartzberg PL, Burkhardt JK. Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP Current Biology. 13: 1619-1624. PMID 13678593 DOI: 10.1016/j.cub.2003.08.005  0.6
2003 Panchal SC, Kaiser DA, Torres E, Pollard TD, Rosen MK. A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex. Nature Structural Biology. 10: 591-8. PMID 12872157 DOI: 10.1038/nsb952  0.6
2003 Garrard SM, Capaldo CT, Gao L, Rosen MK, Macara IG, Tomchick DR. Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6. The Embo Journal. 22: 1125-33. PMID 12606577 DOI: 10.1093/emboj/cdg110  0.48
2002 Chook YM, Jung A, Rosen MK, Blobel G. Uncoupling Kapbeta2 substrate dissociation and ran binding. Biochemistry. 41: 6955-66. PMID 12033928 DOI: 10.1021/bi012122p  0.6
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