| Year |
Citation |
Score |
| 2023 |
Vela-Rodríguez C, Scarpulla I, Ashok Y, Lehtiö L. Discovery of DTX3L inhibitors through a homogeneous FRET-based assay that monitors formation and removal of poly-ubiquitin chains. Slas Discovery : Advancing Life Sciences R & D. PMID 37579950 DOI: 10.1016/j.slasd.2023.08.005 |
0.634 |
|
| 2023 |
Murthy S, Nizi MG, Maksimainen MM, Massari S, Alaviuhkola J, Lippok BE, Vagaggini C, Sowa ST, Galera-Prat A, Ashok Y, Venkannagari H, Prunskaite-Hyyryläinen R, Dreassi E, Lüscher B, Korn P, et al. [1,2,4]Triazolo[3,4-]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. Journal of Medicinal Chemistry. PMID 36598465 DOI: 10.1021/acs.jmedchem.2c01460 |
0.695 |
|
| 2022 |
Ashok Y, Vela-Rodríguez C, Yang CS, Alanen HI, Liu F, Paschal BM, Lehtiö L. Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimerization and multimeric assembly. The Biochemical Journal. PMID 35037691 DOI: 10.1042/BCJ20210722 |
0.622 |
|
| 2020 |
Ashok Y, Maksimainen MM, Kallio T, Kilpeläinen P, Lehtiö L. FMN-dependent oligomerization of putative lactate oxidase from Pediococcus acidilactici. Plos One. 15: e0223870. PMID 32092083 DOI: 10.2210/Pdb6Rht/Pdb |
0.618 |
|
| 2020 |
Ashok Y, Miettinen M, Kimio Hirabae de Oliveira D, Tamirat M, Näreoja K, Tiwari A, Hottiger MO, Johnson M, Lehtiö L, Pulliainen AT. Discovery of compounds inhibiting the ADP-ribosyltransferase activity of pertussis toxin. Acs Infectious Diseases. PMID 31899865 DOI: 10.1021/Acsinfecdis.9B00412 |
0.685 |
|
| 2018 |
Murthy S, Desantis J, Verheugd P, Maksimainen MM, Venkannagari H, Massari S, Ashok Y, Obaji E, Nkizinkinko Y, Lüscher B, Tabarrini O, Lehtiö L. 4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10. European Journal of Medicinal Chemistry. 156: 93-102. PMID 30006177 DOI: 10.1016/J.Ejmech.2018.06.047 |
0.689 |
|
| 2016 |
Venkannagari H, Verheugd P, Koivunen J, Haikarainen T, Obaji E, Ashok Y, Narwal M, Pihlajaniemi T, Lüscher B, Lehtiö L. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. Cell Chemical Biology. PMID 27667561 DOI: 10.1016/J.Chembiol.2016.08.012 |
0.668 |
|
| 2016 |
Ashok Y, Jaakola VP. Nanodisc-Tm: Rapid functional assessment of nanodisc reconstituted membrane proteins by CPM assay. Methodsx. 3: 212-8. PMID 27054097 DOI: 10.1016/J.Mex.2016.03.009 |
0.651 |
|
| 2015 |
Rehan S, Ashok Y, Nanekar R, Jaakola VP. Thermodynamics and kinetics of inhibitor binding to human equilibrative nucleoside transporter subtype-1. Biochemical Pharmacology. PMID 26428002 DOI: 10.1016/J.Bcp.2015.09.019 |
0.669 |
|
| 2015 |
Ashok Y, Nanekar R, Jaakola VP. Defining thermostability of membrane proteins by western blotting. Protein Engineering, Design & Selection : Peds. 28: 539-42. PMID 26384510 DOI: 10.1093/Protein/Gzv049 |
0.656 |
|
| 2013 |
Ashok Y, Nanekar RT, Jaakola VP. Crystallogenesis of adenosine A(2A) receptor-T4 lysozyme fusion protein: a practical route for the structure. Methods in Enzymology. 520: 175-98. PMID 23332700 DOI: 10.1016/B978-0-12-391861-1.00008-3 |
0.67 |
|
| 2011 |
Piirainen H, Ashok Y, Nanekar RT, Jaakola VP. Structural features of adenosine receptors: from crystal to function. Biochimica Et Biophysica Acta. 1808: 1233-44. PMID 20595055 DOI: 10.1016/J.Bbamem.2010.05.021 |
0.663 |
|
| 2009 |
Ashok Y. Drosophila toll pathway: the new model. Science Signaling. 2: jc1. PMID 19126860 DOI: 10.1126/Scisignal.252Jc1 |
0.323 |
|
| Show low-probability matches. |