Kenneth Walsh - Publications

Affiliations: 
Boston University School of Medicine, Boston, MA 
Area:
cardiovascular cell growth, differentiation and apoptosis
Website:
https://www.bumc.bu.edu/busm/profile/kenneth-walsh/

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. PMID 31170826 DOI: 10.1161/CIRCULATIONAHA.118.038820  1
2019 Kivelä R, Hemanthakumar KA, Vaparanta K, Robciuc M, Izumiya Y, Kidoya H, Takakura N, Peng X, Sawyer DB, Elenius K, Walsh K, Alitalo K. Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2 -Mediated Paracrine Signaling. Circulation. PMID 30922063 DOI: 10.1161/CIRCULATIONAHA.118.036099  1
2019 Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, ... Walsh K, et al. Self-reactive CD4 IL-3 T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis. The Journal of Experimental Medicine. PMID 30670465 DOI: 10.1084/jem.20180722  1
2018 Sano S, Wang Y, Walsh K. Clonal Hematopoiesis and Its Impact on Cardiovascular Disease. Circulation Journal : Official Journal of the Japanese Circulation Society. PMID 30185689 DOI: 10.1253/circj.CJ-18-0871  1
2018 Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. Journal of the American Heart Association. 7. PMID 29887522 DOI: 10.1161/JAHA.117.008441  1
2018 Sano S, Ohshima K, Wang Y, Katanasaka Y, Sano M, Walsh K. CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease. Circulation Research. PMID 29728415 DOI: 10.1161/CIRCRESAHA.118.313225  1
2018 Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K. Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome. Journal of the American College of Cardiology. 71: 875-886. PMID 29471939 DOI: 10.1016/j.jacc.2017.12.037  1
2018 Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kurishima C, Kim L, Johnson J, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and Chronic Increases of Circulating FSTL1 Normalize Energy Substrate Metabolism in Pacing-Induced Heart Failure. Circulation. Heart Failure. 11: e004486. PMID 29317401 DOI: 10.1161/CIRCHEARTFAILURE.117.004486  1
2017 Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Scientific Reports. 7: 17326. PMID 29229927 DOI: 10.1038/s41598-017-17509-5  1
2017 MacLauchlan S, Zuriaga MA, Fuster JJ, Cuda CM, Jonason J, Behzadi F, Duffen JP, Haines GK, Aprahamian T, Perlman H, Walsh K. Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. Arthritis Research & Therapy. 19: 166. PMID 28724439 DOI: 10.1186/s13075-017-1375-0  1
2017 Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Frontiers in Cardiovascular Medicine. 4: 27. PMID 28529941 DOI: 10.3389/fcvm.2017.00027  1
2017 Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, ... ... Walsh K, et al. Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (New York, N.Y.). PMID 28104796 DOI: 10.1126/science.aag1381  1
2016 Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vascular Medicine (London, England). PMID 27688298 DOI: 10.1177/1358863X16666693  1
2016 Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. Embo Molecular Medicine. PMID 27234440 DOI: 10.15252/emmm.201506151  1
2016 Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease. Circulation Research. 118: 1786-807. PMID 27230642 DOI: 10.1161/CIRCRESAHA.115.306885  1
2016 Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, Naya FJ. miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy. Plos One. 11: e0151515. PMID 26999812 DOI: 10.1371/journal.pone.0151515  1
2015 Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal of the American Heart Association. 5. PMID 26722122 DOI: 10.1161/JAHA.115.002277  1
2015 Nakamura K, Sano S, Fuster JJ, Kikuchi R, Shimizu I, Ohshima K, Katanasaka Y, Ouchi N, Walsh K. Secreted frizzled-related protein 5 diminishes cardiac inflammation and protects the heart from ischemia-reperfusion injury. The Journal of Biological Chemistry. PMID 26631720 DOI: 10.1074/jbc.M115.693937  1
2015 Shimizu I, Walsh K. The Whitening of Brown Fat and Its Implications for Weight Management in Obesity. Current Obesity Reports. 4: 224-9. PMID 26627217 DOI: 10.1007/s13679-015-0157-8  1
2015 Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, ... ... Walsh K, et al. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. PMID 26375005 DOI: 10.1038/nature15372  1
2015 Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N. C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism. Molecular and Cellular Biology. 35: 2173-85. PMID 25870106 DOI: 10.1128/MCB.01518-14  1
2015 Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 64: 1235-48. PMID 25352637 DOI: 10.2337/db14-1164  1
2015 Cheng KK, Akasaki Y, Lecommandeur E, Lindsay RT, Murfitt S, Walsh K, Griffin JL. Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation. Journal of Proteome Research. 14: 342-52. PMID 25231380 DOI: 10.1021/pr500756u  1
2015 Hayakawa S, Ohashi K, Shibata R, Kataoka Y, Miyabe M, Enomoto T, Joki Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Ogawa H, Matsuo K, Hiramatsu-Ito M, van den Hoff MJ, ... Walsh K, et al. Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model. Journal of the American Society of Nephrology : Jasn. 26: 636-46. PMID 25071081 DOI: 10.1681/ASN.2014020210  1
2015 Yoshida S, Fuster JJ, Walsh K. Adiponectin attenuates abdominal aortic aneurysm formation in hyperlipidemic mice Atherosclerosis. 235: 339-346. PMID 24911638 DOI: 10.1016/j.atherosclerosis.2014.05.923  1
2014 Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, ... Walsh K, et al. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nature Medicine. 20: 1464-71. PMID 25362254 DOI: 10.1038/nm.3703  1
2014 Yan X, Sasi SP, Gee H, Lee J, Yang Y, Mehrzad R, Onufrak J, Song J, Enderling H, Agarwal A, Rahimi L, Morgan J, Wilson PF, Carrozza J, Walsh K, et al. Cardiovascular risks associated with low dose ionizing particle radiation. Plos One. 9: e110269. PMID 25337914 DOI: 10.1371/journal.pone.0110269  1
2014 Tan PH, Tyrrell HE, Gao L, Xu D, Quan J, Gill D, Rai L, Ding Y, Plant G, Chen Y, Xue JZ, Handa AI, Greenall MJ, Walsh K, Xue SA. Adiponectin receptor signaling on dendritic cells blunts antitumor immunity. Cancer Research. 74: 5711-22. PMID 25261236 DOI: 10.1158/0008-5472.CAN-13-1397  1
2014 Zeng L, Maruyama S, Nakamura K, Parker-Duffen JL, Adham IM, Zhong X, Lee HK, Querfurth H, Walsh K. The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis. Skeletal Muscle. 4: 16. PMID 25161767 DOI: 10.1186/2044-5040-4-16  1
2014 Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N. Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity. Circulation. 130: 1072-80. PMID 25116954 DOI: 10.1161/CIRCULATIONAHA.113.008171  1
2014 Hanatani S, Izumiya Y, Araki S, Rokutanda T, Kimura Y, Walsh K, Ogawa H. Akt1-mediated fast/glycolytic skeletal muscle growth attenuates renal damage in experimental kidney disease. Journal of the American Society of Nephrology : Jasn. 25: 2800-11. PMID 25012168 DOI: 10.1681/ASN.2013091025  1
2014 Miyabe M, Ohashi K, Shibata R, Uemura Y, Ogura Y, Yuasa D, Kambara T, Kataoka Y, Yamamoto T, Matsuo K, Joki Y, Enomoto T, Hayakawa S, Hiramatsu-Ito M, Ito M, ... ... Walsh K, et al. Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury. Cardiovascular Research. 103: 111-20. PMID 24743592 DOI: 10.1093/cvr/cvu105  1
2014 Parker-Duffen JL, Nakamura K, Silver M, Zuriaga MA, MacLauchlan S, Aprahamian TR, Walsh K. Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. The Journal of Biological Chemistry. 289: 16200-13. PMID 24742672 DOI: 10.1074/jbc.M114.548115  1
2014 Shimizu I, Aprahamian T, Kikuchi R, Shimizu A, Papanicolaou KN, MacLauchlan S, Maruyama S, Walsh K. Vascular rarefaction mediates whitening of brown fat in obesity. The Journal of Clinical Investigation. 124: 2099-112. PMID 24713652 DOI: 10.1172/JCI71643  1
2014 Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. The Journal of Biological Chemistry. 289: 14178-93. PMID 24711449 DOI: 10.1074/jbc.M114.567743  1
2014 Kwon B, Kumar P, Lee HK, Zeng L, Walsh K, Fu Q, Barakat A, Querfurth HW. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Human Molecular Genetics. 23: 3681-94. PMID 24556217 DOI: 10.1093/hmg/ddu077  1
2014 Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. The Journal of Biological Chemistry. 289: 8633-44. PMID 24482236 DOI: 10.1074/jbc.M113.517219  1
2014 Parker-Duffen JL, Walsh K. Cardiometabolic effects of adiponectin. Best Practice & Research. Clinical Endocrinology & Metabolism. 28: 81-91. PMID 24417948 DOI: 10.1016/j.beem.2013.09.001  1
2014 Nakamura K, Fuster JJ, Walsh K. Adipokines: a link between obesity and cardiovascular disease. Journal of Cardiology. 63: 250-9. PMID 24355497 DOI: 10.1016/j.jjcc.2013.11.006  1
2014 Akasaki Y, Ouchi N, Izumiya Y, Bernardo BL, Lebrasseur NK, Walsh K. Glycolytic fast-twitch muscle fiber restoration counters adverse age-related changes in body composition and metabolism. Aging Cell. 13: 80-91. PMID 24033924 DOI: 10.1111/acel.12153  1
2014 Farb MG, Tiwari S, Karki S, Ngo DT, Carmine B, Hess DT, Zuriaga MA, Walsh K, Fetterman JL, Hamburg NM, Vita JA, Apovian CM, Gokce N. Cyclooxygenase inhibition improves endothelial vasomotor dysfunction of visceral adipose arterioles in human obesity. Obesity (Silver Spring, Md.). 22: 349-55. PMID 23640904 DOI: 10.1002/oby.20505  1
2013 Uchida S, De Gaspari P, Kostin S, Jenniches K, Kilic A, Izumiya Y, Shiojima I, Grosse Kreymborg K, Renz H, Walsh K, Braun T. Sca1-derived cells are a source of myocardial renewal in the murine adult heart. Stem Cell Reports. 1: 397-410. PMID 24286028 DOI: 10.1016/j.stemcr.2013.09.004  1
2013 Parker-Duffen JL, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel MS, Ranscht B, Walsh K. T-cadherin is essential for adiponectin-mediated revascularization. The Journal of Biological Chemistry. 288: 24886-97. PMID 23824191 DOI: 10.1074/jbc.M113.454835  1
2013 Yoshida S, Aihara K, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama K, Akaike M, Matsumoto M, ... ... Walsh K, et al. Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling. Circulation. 128: 60-71. PMID 23723256 DOI: 10.1161/CIRCULATIONAHA.113.001533  1
2013 Shimizu I, Walsh K. Vascular remodeling mediated by Angptl2 produced from perivascular adipose tissue. Journal of Molecular and Cellular Cardiology. 59: 176-8. PMID 23528806 DOI: 10.1016/j.yjmcc.2013.03.009  1
2013 Kasumov T, Dabkowski ER, Shekar KC, Li L, Ribeiro RF, Walsh K, Previs SF, Sadygov RG, Willard B, Stanley WC. Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1201-14. PMID 23457012 DOI: 10.1152/ajpheart.00933.2012  1
2013 Li Y, Wong K, Walsh K, Gao B, Zang M. Retinoic acid receptor β stimulates hepatic induction of fibroblast growth factor 21 to promote fatty acid oxidation and control whole-body energy homeostasis in mice Journal of Biological Chemistry. 288: 10490-10504. PMID 23430257 DOI: 10.1074/jbc.M112.429852  1
2013 Zhu Y, Pereira RO, O'Neill BT, Riehle C, Ilkun O, Wende AR, Rawlings TA, Zhang YC, Zhang Q, Klip A, Shiojima I, Walsh K, Abel ED. Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation. Molecular Endocrinology (Baltimore, Md.). 27: 172-84. PMID 23204326 DOI: 10.1210/me.2012-1210  1
2013 Fetalvero KM, Yu Y, Goetschkes M, Liang G, Valdez RA, Gould T, Triantafellow E, Bergling S, Loureiro J, Eash J, Lin V, Porter JA, Finan PM, Walsh K, Yang Y, et al. Defective autophagy and mTORC1 signaling in myotubularin null mice. Molecular and Cellular Biology. 33: 98-110. PMID 23109424 DOI: 10.1128/MCB.01075-12  1
2013 Wanninger J, Liebisch G, Schmitz G, Bauer S, Eisinger K, Neumeier M, Ouchi N, Walsh K, Buechler C. Lipidomic analysis of the liver identifies changes of major and minor lipid species in adiponectin deficient mice. Experimental and Molecular Pathology. 94: 412-7. PMID 22465357 DOI: 10.1016/j.yexmp.2012.03.008  1
2012 Shimano M, Ouchi N, Walsh K. Cardiokines: recent progress in elucidating the cardiac secretome. Circulation. 126: e327-32. PMID 23169257 DOI: 10.1161/CIRCULATIONAHA.112.150656  1
2012 Shiojima I, Schiekofer S, Schneider JG, Belisle K, Sato K, Andrassy M, Galasso G, Walsh K. Short-term akt activation in cardiac muscle cells improves contractile function in failing hearts. The American Journal of Pathology. 181: 1969-76. PMID 23031259 DOI: 10.1016/j.ajpath.2012.08.020  1
2012 Ogura Y, Ouchi N, Ohashi K, Shibata R, Kataoka Y, Kambara T, Kito T, Maruyama S, Yuasa D, Matsuo K, Enomoto T, Uemura Y, Miyabe M, Ishii M, Yamamoto T, ... ... Walsh K, et al. Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models. Circulation. 126: 1728-38. PMID 22929303 DOI: 10.1161/CIRCULATIONAHA.112.115089  1
2012 Panse KD, Felkin LE, López-Olañeta MM, Gómez-Salinero J, Villalba M, Muñoz L, Nakamura K, Shimano M, Walsh K, Barton PJ, Rosenthal N, Lara-Pezzi E. Follistatin-like 3 mediates paracrine fibroblast activation by cardiomyocytes. Journal of Cardiovascular Translational Research. 5: 814-26. PMID 22915069 DOI: 10.1007/s12265-012-9400-9  1
2012 Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K. Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circulation Research. 111: 1012-26. PMID 22904094 DOI: 10.1161/CIRCRESAHA.112.274142  1
2012 Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, ... ... Walsh K, et al. Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell. 149: 1298-313. PMID 22682250 DOI: 10.1016/j.cell.2012.03.047  1
2012 Widera C, Giannitsis E, Kempf T, Korf-Klingebiel M, Fiedler B, Sharma S, Katus HA, Asaumi Y, Shimano M, Walsh K, Wollert KC. Identification of follistatin-like 1 by expression cloning as an activator of the growth differentiation factor 15 gene and a prognostic biomarker in acute coronary syndrome. Clinical Chemistry. 58: 1233-41. PMID 22675198 DOI: 10.1373/clinchem.2012.182816  1
2012 Ouchi N, Walsh K. Cardiovascular and metabolic regulation by the adiponectin/C1q/tumor necrosis factor-related protein family of proteins. Circulation. 125: 3066-8. PMID 22653085 DOI: 10.1161/CIRCULATIONAHA.112.114181  1
2012 Papanicolaou KN, Phillippo MM, Walsh K. Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion. American Journal of Physiology. Heart and Circulatory Physiology. 303: H243-55. PMID 22636681 DOI: 10.1152/ajpheart.00185.2012  1
2012 Lee HK, Rocnik E, Fu Q, Kwon B, Zeng L, Walsh K, Querfurth H. Foxo/atrogin induction in human and experimental myositis. Neurobiology of Disease. 46: 463-75. PMID 22590725  1
2012 Ngoh GA, Papanicolaou KN, Walsh K. Loss of mitofusin 2 promotes endoplasmic reticulum stress. The Journal of Biological Chemistry. 287: 20321-32. PMID 22511781 DOI: 10.1074/jbc.M112.359174  1
2012 Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation. 125: 1757-64, S1-6. PMID 22388319 DOI: 10.1161/CIRCULATIONAHA.111.067801  1
2012 Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. Journal of Immunology (Baltimore, Md. : 1950). 188: 854-63. PMID 22156343 DOI: 10.4049/jimmunol.1100426  1
2012 Araki S, Izumiya Y, Hanatani S, Rokutanda T, Usuku H, Akasaki Y, Takeo T, Nakagata N, Walsh K, Ogawa H. Akt1-mediated skeletal muscle growth attenuates cardiac dysfunction and remodeling after experimental myocardial infarction. Circulation. Heart Failure. 5: 116-25. PMID 22135402 DOI: 10.1161/CIRCHEARTFAILURE.111.964783  1
2012 Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. American Journal of Physiology. Heart and Circulatory Physiology. 302: H167-79. PMID 22037195 DOI: 10.1152/ajpheart.00833.2011  1
2012 Ionescu LI, Alphonse RS, Arizmendi N, Morgan B, Abel M, Eaton F, Duszyk M, Vliagoftis H, Aprahamian TR, Walsh K, Thébaud B. Airway delivery of soluble factors from plastic-adherent bone marrow cells prevents murine asthma American Journal of Respiratory Cell and Molecular Biology. 46: 207-216. PMID 21903873 DOI: 10.1165/rcmb.2010-0391OC  1
2011 Shimano M, Ouchi N, Nakamura K, van Wijk B, Ohashi K, Asaumi Y, Higuchi A, Pimentel DR, Sam F, Murohara T, van den Hoff MJ, Walsh K. Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload. Proceedings of the National Academy of Sciences of the United States of America. 108: E899-906. PMID 21987816 DOI: 10.1073/pnas.1108559108  1
2011 Enomoto T, Ohashi K, Shibata R, Higuchi A, Maruyama S, Izumiya Y, Walsh K, Murohara T, Ouchi N. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. The Journal of Biological Chemistry. 286: 34552-8. PMID 21849507 DOI: 10.1074/jbc.M111.277319  1
2011 Lugus JJ, Ngoh GA, Bachschmid MM, Walsh K. Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells. Journal of Molecular and Cellular Cardiology. 51: 885-93. PMID 21839087 DOI: 10.1016/j.yjmcc.2011.07.023  1
2011 Craige SM, Chen K, Pei Y, Li C, Huang X, Chen C, Shibata R, Sato K, Walsh K, Keaney JF. NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activation. Circulation. 124: 731-40. PMID 21788590 DOI: 10.1161/CIRCULATIONAHA.111.030775  1
2011 Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1664-79. PMID 21321189 DOI: 10.1096/fj.10-173492  1
2011 Papanicolaou KN, Khairallah RJ, Ngoh GA, Chikando A, Luptak I, O'Shea KM, Riley DD, Lugus JJ, Colucci WS, Lederer WJ, Stanley WC, Walsh K. Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Molecular and Cellular Biology. 31: 1309-28. PMID 21245373 DOI: 10.1128/MCB.00911-10  1
2011 Shimano M, Ouchi N, Nakamura K, Oshima Y, Higuchi A, Pimentel DR, Panse KD, Lara-Pezzi E, Lee SJ, Sam F, Walsh K. Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy. The Journal of Biological Chemistry. 286: 9840-8. PMID 21245136 DOI: 10.1074/jbc.M110.197079  1
2011 Kim MH, Kay DI, Rudra RT, Chen BM, Hsu N, Izumiya Y, Martinez L, Spencer MJ, Walsh K, Grinnell AD, Crosbie RH. Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice. Human Molecular Genetics. 20: 1324-38. PMID 21245083 DOI: 10.1093/hmg/ddr015  1
2010 Zeng L, Akasaki Y, Sato K, Ouchi N, Izumiya Y, Walsh K. Insulin-like 6 is induced by muscle injury and functions as a regenerative factor. The Journal of Biological Chemistry. 285: 36060-9. PMID 20807758 DOI: 10.1074/jbc.M110.160879  1
2010 Ouchi N, Higuchi A, Ohashi K, Oshima Y, Gokce N, Shibata R, Akasaki Y, Shimono A, Walsh K. Sfrp5 is an anti-inflammatory adipokine that modulates metabolic dysfunction in obesity. Science (New York, N.Y.). 329: 454-7. PMID 20558665 DOI: 10.1126/science.1188280  1
2010 Ohashi K, Ouchi N, Higuchi A, Shaw RJ, Walsh K. LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. The Journal of Biological Chemistry. 285: 22291-8. PMID 20489196 DOI: 10.1074/jbc.M110.123794  1
2010 Papanicolaou KN, Streicher JM, Ishikawa TO, Herschman H, Wang Y, Walsh K. Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. Journal of Molecular and Cellular Cardiology. 49: 196-209. PMID 20399788 DOI: 10.1016/j.yjmcc.2010.04.002  1
2010 Shimano M, Ouchi N, Shibata R, Ohashi K, Pimentel DR, Murohara T, Walsh K. Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. Journal of Molecular and Cellular Cardiology. 49: 210-20. PMID 20206634 DOI: 10.1016/j.yjmcc.2010.02.021  1
2010 McCalmon SA, Desjardins DM, Ahmad S, Davidoff KS, Snyder CM, Sato K, Ohashi K, Kielbasa OM, Mathew M, Ewen EP, Walsh K, Gavras H, Naya FJ. Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2. Circulation Research. 106: 952-60. PMID 20093629 DOI: 10.1161/CIRCRESAHA.109.209007  1
2010 Ouchi N, Asaumi Y, Ohashi K, Higuchi A, Sono-Romanelli S, Oshima Y, Walsh K. DIP2A functions as a FSTL1 receptor. The Journal of Biological Chemistry. 285: 7127-34. PMID 20054002 DOI: 10.1074/jbc.M109.069468  1
2010 Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, Summer R, Walsh K. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. The Journal of Biological Chemistry. 285: 6153-60. PMID 20028977 DOI: 10.1074/jbc.M109.088708  1
2010 Higuchi A, Ohashi K, Shibata R, Sono-Romanelli S, Walsh K, Ouchi N. Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 46-53. PMID 19910632 DOI: 10.1161/ATVBAHA.109.198465  1
2010 Sam F, Duhaney TA, Sato K, Wilson RM, Ohashi K, Sono-Romanelli S, Higuchi A, De Silva DS, Qin F, Walsh K, Ouchi N. Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure. Endocrinology. 151: 322-31. PMID 19850745 DOI: 10.1210/en.2009-0806  1
2009 Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K. Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. The Journal of Biological Chemistry. 284: 35839-49. PMID 19828446 DOI: 10.1074/jbc.M109.057273  1
2009 Oshima Y, Ouchi N, Shimano M, Pimentel DR, Papanicolaou KN, Panse KD, Tsuchida K, Lara-Pezzi E, Lee SJ, Walsh K. Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. Circulation. 120: 1606-15. PMID 19805648 DOI: 10.1161/CIRCULATIONAHA.109.872200  1
2009 Ohashi K, Ouchi N, Sato K, Higuchi A, Ishikawa TO, Herschman HR, Kihara S, Walsh K. Adiponectin promotes revascularization of ischemic muscle through a cyclooxygenase 2-dependent mechanism. Molecular and Cellular Biology. 29: 3487-99. PMID 19398582 DOI: 10.1128/MCB.00126-09  1
2009 Higuchi A, Ohashi K, Kihara S, Walsh K, Ouchi N. Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression. Circulation Research. 104: 1058-65. PMID 19342600 DOI: 10.1161/CIRCRESAHA.109.194506  1
2009 Aprahamian T, Bonegio RG, Richez C, Yasuda K, Chiang LK, Sato K, Walsh K, Rifkin IR. The peroxisome proliferator-activated receptor gamma agonist rosiglitazone ameliorates murine lupus by induction of adiponectin. Journal of Immunology (Baltimore, Md. : 1950). 182: 340-6. PMID 19109165  1
2009 Peter AK, Ko CY, Kim MH, Hsu N, Ouchi N, Rhie S, Izumiya Y, Zeng L, Walsh K, Crosbie RH. Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy. Human Molecular Genetics. 18: 318-27. PMID 18986978 DOI: 10.1093/hmg/ddn358  1
2008 Izumiya Y, Bina HA, Ouchi N, Akasaki Y, Kharitonenkov A, Walsh K. FGF21 is an Akt-regulated myokine. Febs Letters. 582: 3805-10. PMID 18948104 DOI: 10.1016/j.febslet.2008.10.021  1
2008 Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K. Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism. The Journal of Biological Chemistry. 283: 32802-11. PMID 18718903 DOI: 10.1074/jbc.M803440200  1
2008 Song Y, Coleman L, Shi J, Beppu H, Sato K, Walsh K, Loscalzo J, Zhang YY. Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H677-90. PMID 18552156 DOI: 10.1152/ajpheart.91519.2007  1
2008 Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 117: 3099-108. PMID 18519848 DOI: 10.1161/CIRCULATIONAHA.108.767673  1
2008 Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, Lan F, Walsh K, Wierzbicki M, Verbeuren TJ, Cohen RA, Zang M. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. The Journal of Biological Chemistry. 283: 20015-26. PMID 18482975 DOI: 10.1074/jbc.M802187200  1
2008 Aprahamian T, Takemura Y, Goukassian D, Walsh K. Ageing is associated with diminished apoptotic cell clearance in vivo. Clinical and Experimental Immunology. 152: 448-55. PMID 18422728 DOI: 10.1111/j.1365-2249.2008.03658.x  1
2008 Ikeda Y, Ohashi K, Shibata R, Pimentel DR, Kihara S, Ouchi N, Walsh K. Cyclooxygenase-2 induction by adiponectin is regulated by a sphingosine kinase-1 dependent mechanism in cardiac myocytes. Febs Letters. 582: 1147-50. PMID 18339320 DOI: 10.1016/j.febslet.2008.03.002  1
2008 Summer R, Little FF, Ouchi N, Takemura Y, Aprahamian T, Dwyer D, Fitzsimmons K, Suki B, Parameswaran H, Fine A, Walsh K. Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1035-42. PMID 18326826 DOI: 10.1152/ajplung.00397.2007  1
2008 Izumiya Y, Hopkins T, Morris C, Sato K, Zeng L, Viereck J, Hamilton JA, Ouchi N, LeBrasseur NK, Walsh K. Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice. Cell Metabolism. 7: 159-72. PMID 18249175 DOI: 10.1016/j.cmet.2007.11.003  1
2008 Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circulation Research. 102: 16-31. PMID 18174472 DOI: 10.1161/CIRCRESAHA.107.164186  1
2007 Takemura Y, Walsh K, Ouchi N. Adiponectin and cardiovascular inflammatory responses. Current Atherosclerosis Reports. 9: 238-43. PMID 18241619  1
2007 Shibata R, Izumiya Y, Sato K, Papanicolaou K, Kihara S, Colucci WS, Sam F, Ouchi N, Walsh K. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. Journal of Molecular and Cellular Cardiology. 42: 1065-74. PMID 17499764 DOI: 10.1016/j.yjmcc.2007.03.808  1
2007 Shibata R, Sato K, Kumada M, Izumiya Y, Sonoda M, Kihara S, Ouchi N, Walsh K. Adiponectin accumulates in myocardial tissue that has been damaged by ischemia-reperfusion injury via leakage from the vascular compartment Cardiovascular Research. 74: 471-479. PMID 17362898 DOI: 10.1016/j.cardiores.2007.02.010  1
2007 Ouchi N, Walsh K. Adiponectin as an anti-inflammatory factor. Clinica Chimica Acta; International Journal of Clinical Chemistry. 380: 24-30. PMID 17343838 DOI: 10.1016/j.cca.2007.01.026  1
2007 Hopkins TA, Ouchi N, Shibata R, Walsh K. Adiponectin actions in the cardiovascular system. Cardiovascular Research. 74: 11-8. PMID 17140553 DOI: 10.1016/j.cardiores.2006.10.009  1
2006 Schiekofer S, Shiojima I, Sato K, Galasso G, Oshima Y, Walsh K. Microarray analysis of Akt1 activation in transgenic mouse hearts reveals transcript expression profiles associated with compensatory hypertrophy and failure. Physiological Genomics. 27: 156-70. PMID 16882883 DOI: 10.1152/physiolgenomics.00234.2005  1
2006 Ouchi N, Shibata R, Walsh K. Targeting adiponectin for cardioprotection. Expert Opinion On Therapeutic Targets. 10: 573-81. PMID 16848693 DOI: 10.1517/14728222.10.4.573   1
2006 Ouchi N, Shibata R, Walsh K. Cardioprotection by adiponectin. Trends in Cardiovascular Medicine. 16: 141-6. PMID 16781946 DOI: 10.1016/j.tcm.2006.03.001  1
2006 Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 47: 887-93. PMID 16567591 DOI: 10.1161/01.HYP.0000215207.54689.31  1
2005 Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nature Medicine. 11: 1096-103. PMID 16155579 DOI: 10.1038/nm1295  1
2005 Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. The Journal of Clinical Investigation. 115: 2108-18. PMID 16075055 DOI: 10.1172/JCI24682  1
2005 Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. The Journal of Biological Chemistry. 280: 20814-23. PMID 15781459 DOI: 10.1074/jbc.M500528200  1
2005 Taniyama Y, Ito M, Sato K, Kuester C, Veit K, Tremp G, Liao R, Colucci WS, Ivashchenko Y, Walsh K, Shiojima I. Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy. Journal of Molecular and Cellular Cardiology. 38: 375-85. PMID 15698844 DOI: 10.1016/j.yjmcc.2004.12.002  1
2004 Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart Nature Medicine. 10: 1384-1389. PMID 15558058 DOI: 10.1038/nm1137  1
2003 Yang J, Jones SP, Suhara T, Greer JJ, Ware PD, Nguyen NP, Perlman H, Nelson DP, Lefer DJ, Walsh K. Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart. The Journal of Biological Chemistry. 278: 15185-91. PMID 12576484 DOI: 10.1074/jbc.M211707200  1
2000 Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against lschemia-reperfusion injury in mouse heart Circulation. 101: 660-667. PMID 10673259  1
1996 Suzuki E, Evans T, Lowry J, Truong L, Bell DW, Testa JR, Walsh K. The human GATA-6 gene: Structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals Genomics. 38: 283-290. PMID 8975704 DOI: 10.1006/geno.1996.0630  1
1987 Walsh K, Schena M, Flint AJ, Koshland DE. Compensatory regulation in metabolic pathways--responses to increases and decreases in citrate synthase levels. Biochemical Society Symposium. 54: 183-95. PMID 3332995  1
1985 Walsh K, Koshland DE. Characterization of rate-controlling steps in vivo by use of an adjustable expression vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 3577-81. PMID 3889909  1
1985 Koshland DE, Walsh K, LaPorte DC. Sensitivity of metabolic fluxes to covalent control Current Topics in Cellular Regulation. 27: 13-22. PMID 3004815  1
1985 Walsh K, Koshland DE. Branch point control by the phosphorylation state of isocitrate dehydrogenase. A quantitative examination of fluxes during a regulatory transition. The Journal of Biological Chemistry. 260: 8430-7. PMID 2861202  1
1984 LaPorte DC, Walsh K, Koshland DE. The branch point effect. Ultrasensitivity and subsensitivity to metabolic control Journal of Biological Chemistry. 259: 14068-14075. PMID 6389540  1
1984 Walsh K, Koshland DE. Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt. The Journal of Biological Chemistry. 259: 9646-54. PMID 6378912  1
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