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Jianghai Zhu, Ph.D. - Publications

Affiliations: 
2005 Purdue University, West Lafayette, IN, United States 
Area:
General Biophysics
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Holzwarth ST, Bayat B, Zhu J, Phuangtham R, Fischer L, Boeckelmann D, Röder L, Berghöfer H, Schmidt S, Bein G, Santoso S. Naturally occurring point mutation Cys460Trp located in the I-EGF1 domain of integrin β3 alters the binding of some anti-HPA-1a antibodies. Transfusion. 60: 2097-2107. PMID 32770549 DOI: 10.1111/Trf.15960  0.34
2018 Zhi H, Ahlen MT, Thinn AMM, Weiler H, Curtis BR, Skogen B, Zhu J, Newman PJ. High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl). Blood Advances. 2: 3001-3011. PMID 30413435 DOI: 10.1182/Bloodadvances.2018023341  0.351
2018 Thinn AMM, Wang Z, Zhou D, Zhao Y, Curtis BR, Zhu J. Autonomous conformational regulation of β integrin and the conformation-dependent property of HPA-1a alloantibodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30209215 DOI: 10.1073/Pnas.1806205115  0.414
2018 Zhou D, Thinn AMM, Zhao Y, Wang Z, Zhu J. Structure of an extended β integrin. Blood. PMID 30018079 DOI: 10.1182/Blood-2018-01-829572  0.44
2018 Thinn AMM, Wang Z, Zhu J. The membrane-distal regions of integrin α cytoplasmic domains contribute differently to integrin inside-out activation. Scientific Reports. 8: 5067. PMID 29568062 DOI: 10.1038/S41598-018-23444-W  0.359
2017 Wang Z, Thinn AMM, Zhu J. A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding. The Journal of Biological Chemistry. PMID 29079572 DOI: 10.1074/Jbc.M117.790519  0.472
2017 Bondu V, Wu C, Cao W, Simons PC, Gillette J, Zhu J, Erb L, Zhang XF, Buranda T. Low affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection. Molecular Biology of the Cell. PMID 28835374 DOI: 10.1091/Mbc.E17-01-0082  0.458
2017 Cai X, Thinn AMM, Wang Z, Shan H, Zhu J. The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation. Scientific Reports. 7: 4656. PMID 28680094 DOI: 10.1038/S41598-017-04844-W  0.354
2017 Dong X, Zhao B, Iacob RE, Zhu J, Koksal AC, Lu C, Engen JR, Springer TA. Force interacts with macromolecular structure in activation of TGF-β. Nature. PMID 28117447 DOI: 10.1038/Nature21035  0.402
2016 Lertkiatmongkol P, Paddock C, Newman DK, Zhu J, Thomas MJ, Newman PJ. The role of sialylated glycans in human PECAM-1-mediated trans-homophilic interactions and endothelial cell barrier function. The Journal of Biological Chemistry. PMID 27793989 DOI: 10.1074/Jbc.M116.756502  0.367
2016 Lin FY, Zhu J, Eng ET, Hudson NE, Springer TA. beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece. Journal of Biological Chemistry. 291: 4537-4546. DOI: 10.2210/Pdb4Z7O/Pdb  0.333
2015 Paddock C, Zhou D, Lertkiatmongkol P, Newman PJ, Zhu J. Structural basis for PECAM-1 homophilic binding. Blood. PMID 26702061 DOI: 10.1182/Blood-2015-07-660092  0.453
2015 Lin FY, Zhu J, Eng ET, Hudson NE, Springer TA. β-subunit Binding is Sufficient for Ligands to open the Integrin αIIbβ3 Headpiece. The Journal of Biological Chemistry. PMID 26631735 DOI: 10.1074/Jbc.M115.705624  0.457
2015 Zhi H, Dai J, Liu J, Zhu J, Newman DK, Gao C, Newman PJ. Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase. Plos One. 10: e0135738. PMID 26291522 DOI: 10.1371/Journal.Pone.0135738  0.309
2015 Zhu J, Zhu J, Bougie DW, Aster RH, Springer TA. Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3. Blood. 126: 2138-45. PMID 26282540 DOI: 10.1182/Blood-2015-04-639351  0.366
2015 Liu J, Wang Z, Thinn AM, Ma YQ, Zhu J. The dual structural roles of the membrane distal region of the α-integrin cytoplasmic tail during integrin inside-out activation. Journal of Cell Science. 128: 1718-31. PMID 25749862 DOI: 10.1242/Jcs.160663  0.408
2015 Thinn AMM, Zhu J. Structure and Sequence Diversity of the Membrane Distal Region of α-Cytoplasmic Tail in Integrin Activation Blood. 126: 3453-3453. DOI: 10.1182/Blood.V126.23.3453.3453  0.369
2015 Montgomery RR, Flood VH, Zhu J, Christopherson PA, Newman PJ, Bougie DW, Morateck P. Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD Blood. 126: 1107-1107. DOI: 10.1182/Blood.V126.23.1107.1107  0.416
2014 Dai B, Wu P, Xue F, Yang R, Yu Z, Dai K, Ruan C, Zhu J, Newman PJ, Gao C. Integrin αIIbβ3-Mediated Outside-in Signaling: Brake or Amplifier of Platelet Activation? Blood. 124: 4161-4161. DOI: 10.1182/Blood.V124.21.4161.4161  0.35
2014 Zhu J, Liu J, Ma Y, Wang Z. The Dual Structural Roles of the Membrane Distal Region of α Integrin Cytoplasmic Tail in Integrin inside-out Activation Blood. 124: 1431-1431. DOI: 10.1182/Blood.V124.21.1431.1431  0.422
2013 Zhang C, Liu J, Jiang X, Haydar N, Zhang C, Shan H, Zhu J. Modulation of integrin activation and signaling by α1/α1'-helix unbending at the junction. Journal of Cell Science. 126: 5735-47. PMID 24144695 DOI: 10.1242/Jcs.137828  0.407
2013 Zhu J, Zhu J, Springer TA. Complete integrin headpiece opening in eight steps. The Journal of Cell Biology. 201: 1053-68. PMID 23798730 DOI: 10.1083/Jcb.201212037  0.432
2013 Yu Y, Zhu J, Huang PS, Wang JH, Pullen N, Springer TA. Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. The Journal of Biological Chemistry. 288: 6284-94. PMID 23297416 DOI: 10.1074/Jbc.M112.413153  0.448
2013 Wu N, Dai J, Fang J, Liu P, Liu J, Hu H, Zhu J, Newman DK, Newman PJ, Gao C. An Unexpected Role For αIIbβ3 In Immune Complex Disorders Blood. 122: 2293-2293. DOI: 10.1182/Blood.V122.21.2293.2293  0.32
2012 Dong X, Mi LZ, Zhu J, Wang W, Hu P, Luo BH, Springer TA. α(V)β(3) integrin crystal structures and their functional implications. Biochemistry. 51: 8814-28. PMID 23106217 DOI: 10.1021/Bi300734N  0.387
2012 Zhou YF, Eng ET, Zhu J, Lu C, Walz T, Springer TA. Sequence and structure relationships within von Willebrand factor. Blood. 120: 449-58. PMID 22490677 DOI: 10.1182/Blood-2012-01-405134  0.354
2012 Bougie DW, Rasmussen M, Zhu J, Aster RH. Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin Blood. 119: 6317-6325. PMID 22490676 DOI: 10.1182/Blood-2012-01-406322  0.384
2012 Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, et al. Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS. Science Translational Medicine. 4: 125ra32. PMID 22422993 DOI: 10.1126/Scitranslmed.3003576  0.324
2012 Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. GARP regulates the bioavailability and activation of TGFβ. Molecular Biology of the Cell. 23: 1129-39. PMID 22278742 DOI: 10.1091/Mbc.E11-12-1018  0.397
2012 Yu Y, Zhu J, Mi LZ, Walz T, Sun H, Chen J, Springer TA. Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion. The Journal of Cell Biology. 196: 131-46. PMID 22232704 DOI: 10.1083/Jcb.201110023  0.453
2011 Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β structure and activation. Nature. 474: 343-9. PMID 21677751 DOI: 10.1038/Nature10152  0.389
2011 Wang W, Zhu J, Springer TA, Luo BH. Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signaling. The Journal of Biological Chemistry. 286: 1860-7. PMID 21081497 DOI: 10.1074/Jbc.M110.193797  0.417
2011 Zhu J, Choi W, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Thomas CJ, Filizola M, Springer T, Coller BS. Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg2+ From the β3 MIDAS, Blood. 118: 3255-3255. DOI: 10.1182/Blood.V118.21.3255.3255  0.43
2010 Lu C, Mi LZ, Grey MJ, Zhu J, Graef E, Yokoyama S, Springer TA. Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor. Molecular and Cellular Biology. 30: 5432-43. PMID 20837704 DOI: 10.1128/Mcb.00742-10  0.385
2010 Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. Blood. 116: 5050-9. PMID 20679525 DOI: 10.1182/Blood-2010-04-281154  0.452
2010 Xie C, Zhu J, Chen X, Mi L, Nishida N, Springer TA. Structure of an integrin with an alphaI domain, complement receptor type 4. The Embo Journal. 29: 666-79. PMID 20033057 DOI: 10.1038/Emboj.2009.367  0.396
2010 Negri A, Provasi D, Zhu J, Zhu J, Coller BS, Springer TA, Filizola M. Computational Prediction and Experimental Validation of a Novel Binding Site for Platelet Integrin AlphaIIb-Beta3 Biophysical Journal. 98: 40a. DOI: 10.1016/J.Bpj.2009.12.229  0.468
2009 Zhu J, Luo BH, Barth P, Schonbrun J, Baker D, Springer TA. The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3. Molecular Cell. 34: 234-49. PMID 19394300 DOI: 10.1016/J.Molcel.2009.02.022  0.388
2009 Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Structural, Functional, and Dynamic Characterization of the Binding Site of RUC-1, a Novel αIIb-Specific Inhibitor of Integrin αIIbβ3. Blood. 114: 151-151. DOI: 10.1182/Blood.V114.22.151.151  0.477
2008 Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Molecular Cell. 32: 849-61. PMID 19111664 DOI: 10.1016/J.Molcel.2008.11.018  0.401
2008 Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. The Journal of Cell Biology. 182: 791-800. PMID 18710925 DOI: 10.1083/Jcb.200801146  0.389
2007 Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood. 110: 2475-83. PMID 17615290 DOI: 10.1182/Blood-2007-03-080077  0.432
2007 Zhu J, Boylan B, Luo BH, Newman PJ, Springer TA. Tests of the extension and deadbolt models of integrin activation. The Journal of Biological Chemistry. 282: 11914-20. PMID 17301049 DOI: 10.1074/Jbc.M700249200  0.437
2006 Liu Y, Xu Y, Lou Z, Zhu J, Hu X, Gao GF, Qiu B, Rao Z, Tien P. Structural characterization of mumps virus fusion protein core. Biochemical and Biophysical Research Communications. 348: 916-22. PMID 16904649 DOI: 10.1016/J.Bbrc.2006.07.168  0.355
2005 Liu Y, Xu Y, Zhu J, Qiu B, Rao Z, Gao GF, Tien P. Crystallization and preliminary X-ray diffraction analysis of central structure domains from mumps virus F protein. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 855-7. PMID 16511178 DOI: 10.1107/S1744309105025789  0.377
2005 Zhu J, Jiang X, Liu Y, Tien P, Gao GF. Design and characterization of viral polypeptide inhibitors targeting Newcastle disease virus fusion. Journal of Molecular Biology. 354: 601-13. PMID 16253271 DOI: 10.1016/J.Jmb.2005.08.078  0.36
2005 Zhu J, Burgner JW, Harms E, Belitsky BR, Smith JL. A new arrangement of (beta/alpha)8 barrels in the synthase subunit of PLP synthase. The Journal of Biological Chemistry. 280: 27914-23. PMID 15911615 DOI: 10.1074/Jbc.M503642200  0.523
2005 Ni L, Zhu J, Zhang J, Yan M, Gao GF, Tien P. Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain. Biochemical and Biophysical Research Communications. 330: 39-45. PMID 15781229 DOI: 10.1016/J.Bbrc.2005.02.117  0.357
2005 Li S, Zhu J, Peng Y, Cui S, Wang C, Gao GF, Tien P. Characterization of BIV Env core: implication for mechanism of BIV-mediated cell fusion. Biochemical and Biophysical Research Communications. 329: 603-9. PMID 15737628 DOI: 10.1016/J.Bbrc.2005.01.160  0.319
2004 Xu Y, Zhu J, Liu Y, Lou Z, Yuan F, Liu Y, Cole DK, Ni L, Su N, Qin L, Li X, Bai Z, Bell JI, Pang H, Tien P, et al. Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus. Biochemistry. 43: 14064-71. PMID 15518555 DOI: 10.1021/Bi049101Q  0.373
2004 Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P, Gao GF. Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors. Biochemical and Biophysical Research Communications. 319: 283-288. PMID 15158473 DOI: 10.1016/J.Bbrc.2004.04.141  0.329
2004 Liu Y, Zhu J, Feng M, Tien P, Gao GF. Six-helix bundle assembly and analysis of the central core of mumps virus fusion protein. Archives of Biochemistry and Biophysics. 421: 143-148. PMID 14678795 DOI: 10.1016/J.Abb.2003.09.037  0.345
2003 Bera AK, Zhu J, Zalkin H, Smith JL. Functional dissection of the Bacillus subtilis pur operator site. Journal of Bacteriology. 185: 4099-109. PMID 12837784 DOI: 10.1128/Jb.185.14.4099-4109.2003  0.505
2003 Li P, Zhu J, Wu BL, Gao F, Tien P, Rao Z, Gao GF. Crystallization and preliminary X-ray diffraction analysis of post-fusion six-helix bundle core structure from Newcastle disease virus F protein. Acta Crystallographica Section D-Biological Crystallography. 59: 1296-1298. PMID 12832792 DOI: 10.1107/S0907444903009909  0.337
2003 Zhu J, Li P, Wu T, Gao F, Ding Y, Zhang CW, Rao Z, Gao GF, Tien P. Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein. Protein Engineering. 16: 373-9. PMID 12826729 DOI: 10.1093/Protein/Gzg041  0.369
2003 Zhu J, Ding Y, Gao F, Wu T, Zhang CW, Tien P, Rao Z, Gao GF. Crystallization and preliminary X-ray crystallographic analysis of the trimer core from measles virus fusion protein. Acta Crystallographica. Section D, Biological Crystallography. 59: 587-90. PMID 12595734 DOI: 10.1107/S0907444903001057  0.331
2002 Zhu J, Zhang CW-, Qi Y, Tien P, Gao GF. The fusion protein core of measles virus forms stable coiled-coil trimer. Biochemical and Biophysical Research Communications. 299: 897-902. PMID 12470664 DOI: 10.1016/S0006-291X(02)02761-4  0.365
1998 Moyers JS, Zhu J, Kahn CR. Effects of phosphorylation on function of the Rad GTPase. Biochemical Journal. 333: 609-614. PMID 9677319 DOI: 10.1042/Bj3330609  0.327
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