Michael W. Crowder, Ph.D. - Publications

Affiliations: 
Chemistry and Biochemistry Miami University (Ohio), Oxford, OH 
Area:
bioinorganic chemistry
Website:
http://chemistry.muohio.edu/faculty/17-faculty/inorganic-chemistry/5-michael-w-crowder

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cheng Z, Bethel CR, Thomas PW, Shurina BA, Alao JP, Thomas CA, Yang K, Zhang H, Sturgill AM, Kravats AN, Page RC, Fast W, Bonomo RA, Crowder MW. Carbapenem use is driving the evolution of IMiPenemase (IMP)-1 variants. Antimicrobial Agents and Chemotherapy. PMID 33468463 DOI: 10.1128/AAC.01714-20  0.52
2020 Fullington S, Cheng Z, Thomas C, Miller C, Yang K, Ju LC, Bergstrom A, Shurina BA, Bretz SL, Page RC, Tierney DL, Crowder MW. An integrated biophysical approach to discovering mechanisms of NDM-1 inhibition for several thiol-containing drugs. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 32500360 DOI: 10.1007/s00775-020-01794-z  0.4
2020 Chen AY, Thomas C, Thomas PW, Yang K, Cheng Z, Fast W, Crowder MW, Cohen SM.

Iminodiacetic Acid as a Novel Metal-binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development

. Chemmedchem. PMID 32315115 DOI: 10.1002/cmdc.202000123 
0.52
2020 Cheng Z, Thomas CA, Joyner AR, Kimble RL, Sturgill AM, Tran NY, Vulcan MR, Klinsky SA, Orea DJ, Platt CR, Cao F, Li B, Yang Q, Yurkiewicz CJ, Fast W, ... Crowder MW, et al. MBLinhibitors.com, a Website Resource Offering Information and Expertise for the Continued Development of Metallo--Lactamase Inhibitors. Biomolecules. 10. PMID 32188106 DOI: 10.3390/biom10030459  0.52
2019 Cheng Z, Shurina BA, Bethel CR, Thomas PW, Marshall SH, Thomas CA, Yang K, Kimble RL, Montgomery JS, Orischak MG, Miller CM, Tennenbaum JL, Nix JC, Tierney DL, Fast W, ... ... Crowder MW, et al. A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions. Mbio. 10. PMID 31744917 DOI: 10.1128/mBio.02412-19  0.52
2019 Chen AY, Thomas PW, Cheng Z, Xu NY, Tierney DL, Crowder MW, Fast W, Cohen SM. Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-β-Lactamases. Chemmedchem. PMID 31124602 DOI: 10.1002/cmdc.201900172  0.52
2018 Chen AY, Thomas PW, Stewart AC, Bergstrom A, Cheng Z, Miller C, Bethel CR, Marshall SH, Credille CV, Riley CL, Page RC, Bonomo RA, Crowder MW, Tierney DL, Fast W, et al. Correction to Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1. Journal of Medicinal Chemistry. PMID 30019584 DOI: 10.1021/acs.jmedchem.8b01057  0.52
2018 Cheng Z, Thomas PW, Ju L, Bergstrom A, Mason K, Clayton D, Miller C, Bethel CR, VanPelt J, Tierney DL, Page RC, Bonomo RA, Fast W, Crowder MW. Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: effects of NDM mutations on stability, zinc affinity, mono-zinc activity. The Journal of Biological Chemistry. PMID 29909397 DOI: 10.1074/jbc.RA118.003835  0.32
2018 Ju LC, Cheng Z, Fast W, Bonomo RA, Crowder MW. The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters. Trends in Pharmacological Sciences. PMID 29680579 DOI: 10.1016/j.tips.2018.03.007  0.52
2017 Bergstrom A, Katko A, Adkins ZB, Hill JE, Cheng Z, Burnett ML, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, ... ... Crowder MW, et al. Probing the interaction of Aspergillomarasmine A (AMA) with metallo-β-lactamases NDM-1, VIM-2, and IMP-7. Acs Infectious Diseases. PMID 29091730 DOI: 10.1021/acsinfecdis.7b00106  0.52
2017 Lisa MN, Palacios AR, Aitha M, González MM, Moreno DM, Crowder MW, Bonomo RA, Spencer J, Tierney DL, Llarrull LI, Vila AJ. A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases. Nature Communications. 8: 538. PMID 28912448 DOI: 10.1038/s41467-017-00601-9  0.4
2017 Craig WR, Baker TW, Marts AR, DeGenova DT, Martin DP, Reed GC, McCarrick RM, Crowder MW, Cohen SM, Tierney DL. Substituent Effects on the Coordination Chemistry of Metal-Binding Pharmacophores. Inorganic Chemistry. PMID 28898098 DOI: 10.1021/acs.inorgchem.7b01661  0.4
2017 Chen AY, Thomas PW, Stewart AC, Bergstrom A, Cheng Z, Miller C, Bethel CR, Marshall SH, Credille CV, Riley CL, Page RC, Bonomo RA, Crowder MW, Tierney DL, Fast W, et al. Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1. Journal of Medicinal Chemistry. PMID 28809565 DOI: 10.1021/acs.jmedchem.7b00407  0.52
2016 Meng F, Yang H, Jack C, Zhang H, Moller A, Spivey D, Page RC, Tierney DL, Crowder MW. Biochemical characterization and zinc binding group (ZBGs) inhibition studies on the catalytic domain of MMP7 (cdMMP7). Journal of Inorganic Biochemistry. 165: 7-17. PMID 27755977 DOI: 10.1016/j.jinorgbio.2016.10.005  0.64
2016 Meng F, Yang H, Aitha M, George S, Tierney DL, Crowder MW. Biochemical and spectroscopic characterization of the catalytic domain of MMP16 (cdMMP16). Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 27229514 DOI: 10.1007/s00775-016-1362-y  0.4
2016 Aitha M, Al-Adbul-Wahid S, Tierney DL, Crowder MW. Probing substrate binding to the metal binding sites in metallo-β-lactamase L1 during catalysis. Medchemcomm. 7: 194-201. PMID 27087914 DOI: 10.1039/C5MD00358J  0.4
2016 Aitha M, Al-Adbul-Wahid S, Tierney DL, Crowder MW. Probing substrate binding to the metal binding sites in metallo-β-lactamase L1 during catalysis Medchemcomm. 7: 194-201. DOI: 10.1039/c5md00358j  0.64
2015 Aitha M, Moller AJ, Sahu ID, Horitani M, Tierney DL, Crowder MW. Investigating the position of the hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis and inhibitor binding. Journal of Inorganic Biochemistry. 156: 35-39. PMID 26717260 DOI: 10.1016/j.jinorgbio.2015.10.011  0.64
2015 Yang H, Makaroff K, Paz N, Aitha M, Crowder MW, Tierney DL. Metal Ion Dependence of the Matrix Metalloproteinase-1 Mechanism. Biochemistry. 54: 3631-9. PMID 26018933 DOI: 10.1021/acs.biochem.5b00379  0.64
2015 Oelschlaeger P, Aitha M, Yang H, Kang JS, Zhang AL, Liu EM, Buynak JD, Crowder MW. Meropenem and Chromacef Intermediates Observed in IMP-25 Metallo-β-Lactamase-Catalyzed Hydrolysis. Antimicrobial Agents and Chemotherapy. 59: 4326-30. PMID 25918145 DOI: 10.1128/AAC.04409-14  0.64
2015 Aitha M, Moritz L, Sahu ID, Sanyurah O, Roche Z, McCarrick R, Lorigan GA, Bennett B, Crowder MW. Conformational dynamics of metallo-β-lactamase CcrA during catalysis investigated by using DEER spectroscopy. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 585-94. PMID 25827593 DOI: 10.1007/s00775-015-1244-8  0.64
2015 Yang H, Crowder MW. New Delhi metallo-β-lactamase (NDM) Biochemist. 37: 18-21.  0.64
2014 Aitha M, Marts AR, Bergstrom A, Møller AJ, Moritz L, Turner L, Nix JC, Bonomo RA, Page RC, Tierney DL, Crowder MW. Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2. Biochemistry. 53: 7321-31. PMID 25356958 DOI: 10.1021/bi500916y  0.64
2014 Yang H, Young H, Yu S, Sutton L, Crowder MW. Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins. The Biochemical Journal. 464: 271-9. PMID 25220027 DOI: 10.1042/BJ20140364  0.64
2014 Zhang YL, Yang KW, Zhou YJ, LaCuran AE, Oelschlaeger P, Crowder MW. Diaryl-substituted azolylthioacetamides: Inhibitor discovery of New Delhi metallo-β-lactamase-1 (NDM-1) Chemmedchem. 9: 2445-2448. PMID 25048031 DOI: 10.1002/cmdc.201402249  0.64
2014 Yang H, Aitha M, Marts AR, Hetrick A, Bennett B, Crowder MW, Tierney DL. Spectroscopic and mechanistic studies of heterodimetallic forms of metallo-β-lactamase NDM-1. Journal of the American Chemical Society. 136: 7273-85. PMID 24754678 DOI: 10.1021/ja410376s  0.64
2014 Aitha M, Richmond TK, Hu Z, Hetrick A, Reese R, Gunther A, McCarrick R, Bennett B, Crowder MW. Dilution of dipolar interactions in a spin-labeled, multimeric metalloenzyme for DEER studies. Journal of Inorganic Biochemistry. 136: 40-6. PMID 24742748 DOI: 10.1016/j.jinorgbio.2014.03.010  0.64
2013 Yang KW, Feng L, Yang SK, Aitha M, Lacuran AE, Oelschlaeger P, Crowder MW. New β-phospholactam as a carbapenem transition state analog: Synthesis of a broad-spectrum inhibitor of metallo-β-lactamases Bioorganic and Medicinal Chemistry Letters. 23: 5855-5859. PMID 24064498 DOI: 10.1016/j.bmcl.2013.08.098  0.64
2013 Zhang YL, Xiao JM, Feng JL, Yang KW, Feng L, Zhou LS, Crowder MW. A novel fluorogenic substrate for dinuclear Zn(II)-containing metallo-β-lactamases Bioorganic and Medicinal Chemistry Letters. 23: 1676-1679. PMID 23411077 DOI: 10.1016/j.bmcl.2013.01.071  0.64
2013 Heidari Torkabadi H, Che T, Shou J, Shanmugam S, Crowder MW, Bonomo RA, Pusztai-Carey M, Carey PR. Raman spectra of interchanging β-lactamase inhibitor intermediates on the millisecond time scale Journal of the American Chemical Society. 135: 2895-2898. PMID 23406484 DOI: 10.1021/ja311440p  0.64
2013 Zhou LS, Yang KW, Feng L, Xiao JM, Liu CC, Zhang YL, Crowder MW. Novel fluorescent risedronates: synthesis, photodynamic inactivation and imaging of Bacillus subtilis. Bioorganic & Medicinal Chemistry Letters. 23: 949-54. PMID 23321562 DOI: 10.1016/j.bmcl.2012.12.051  0.64
2012 Feng L, Yang KW, Zhou LS, Xiao JM, Yang X, Zhai L, Zhang YL, Crowder MW. N-Heterocyclic dicarboxylic acids: Broad-spectrum inhibitors of metallo-β-lactamases with co-antibacterial effect against antibiotic-resistant bacteria Bioorganic and Medicinal Chemistry Letters. 22: 5185-5189. PMID 22796180 DOI: 10.1016/j.bmcl.2012.06.074  0.64
2012 Yang H, Aitha M, Hetrick AM, Richmond TK, Tierney DL, Crowder MW. Mechanistic and spectroscopic studies of metallo-β-lactamase NDM-1. Biochemistry. 51: 3839-47. PMID 22482529 DOI: 10.1021/bi300056y  0.64
2012 Hensley MP, Gunasekera TS, Easton JA, Sigdel TK, Sugarbaker SA, Klingbeil L, Breece RM, Tierney DL, Crowder MW. Characterization of Zn(II)-responsive ribosomal proteins YkgM and L31 in E. coli. Journal of Inorganic Biochemistry. 111: 164-72. PMID 22196016 DOI: 10.1016/j.jinorgbio.2011.11.022  0.64
2012 Luxford CJ, Crowder MW, Bretz SL. A symmetry pogil activity for inorganic chemistry Cynthia J. Luxford Journal of Chemical Education. 89: 211-214. DOI: 10.1021/ed1007487  0.64
2011 Hensley MP, Tierney DL, Crowder MW. Zn(II) binding to Escherichia coli 70S ribosomes. Biochemistry. 50: 9937-9. PMID 22026583 DOI: 10.1021/bi200619w  0.64
2011 Griffin DH, Richmond TK, Sanchez C, Moller AJ, Breece RM, Tierney DL, Bennett B, Crowder MW. Structural and kinetic studies on metallo-β-lactamase IMP-1. Biochemistry. 50: 9125-34. PMID 21928807 DOI: 10.1021/bi200839h  0.64
2011 Linenberger K, Bretz SL, Crowder MW, McCarrick R, Lorigan GA, Tierney DL. What is the true color of fresh meat? A biophysical undergraduate laboratory experiment investigating the effects of ligand binding on myoglobin using optical, EPR, and NMR spectroscopy Journal of Chemical Education. 88: 223-225. DOI: 10.1021/ed100585t  0.64
2010 Limphong P, Adams NE, Rouhier MF, McKinney RM, Naylor M, Bennett B, Makaroff CA, Crowder MW. Converting GLX2-1 into an active glyoxalase II. Biochemistry. 49: 8228-36. PMID 20715794 DOI: 10.1021/bi1010865  0.64
2010 Limphong P, McKinney RM, Adams NE, Makaroff CA, Bennett B, Crowder MW. The metal ion requirements of Arabidopsis thaliana Glx2-2 for catalytic activity Journal of Biological Inorganic Chemistry. 15: 249-258. PMID 19834746 DOI: 10.1007/s00775-009-0593-6  0.64
2009 Gunasekera TS, Herre AH, Crowder MW. Absence of ZnuABC-mediated zinc uptake affects virulence-associated phenotypes of uropathogenic Escherichia coli CFT073 under Zn(II)-depleted conditions Fems Microbiology Letters. 300: 36-41. PMID 19765083 DOI: 10.1111/j.1574-6968.2009.01762.x  0.64
2009 Limphong P, Nimako G, Thomas PW, Fast W, Makaroff CA, Crowder MW. Arabidopsis thaliana mitochondrial glyoxalase 2-1 exhibits β-lactamase activity Biochemistry. 48: 8491-8493. PMID 19735113 DOI: 10.1021/bi9010539  0.64
2009 Breece RM, Hu Z, Bennett B, Crowder MW, Tierney DL. Motion of the zinc ions in catalysis by a dizinc metallo-beta-lactamase. Journal of the American Chemical Society. 131: 11642-3. PMID 19653676 DOI: 10.1021/ja902534b  0.64
2009 Hawk MJ, Breece RM, Hajdin CE, Bender KM, Hu Z, Costello AL, Bennett B, Tierney DL, Crowder MW. Differential binding of Co(II) and Zn(II) to metallo-beta-lactamase Bla2 from Bacillus anthracis. Journal of the American Chemical Society. 131: 10753-62. PMID 19588962 DOI: 10.1021/ja900296u  0.64
2009 Limphong P, McKinney RM, Adams NE, Bennett B, Makaroff CA, Gunasekera T, Crowder MW. Human glyoxalase II contains an Fe(II)Zn(II) center but is active as a mononuclear Zn(II) enzyme Biochemistry. 48: 5426-5434. PMID 19413286 DOI: 10.1021/bi9001375  0.64
2009 Hu Z, Spadafora LJ, Hajdin CE, Bennett B, Crowder MW. Structure and mechanism of copper- and nickel-substituted analogues of metallo-β-lactamase L1 Biochemistry. 48: 2981-2989. PMID 19228020 DOI: 10.1021/bi802295z  0.64
2009 Salsbury FR, Crowder MW, Kingsmore SF, Huntley JJ. Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor. Journal of Molecular Modeling. 15: 133-45. PMID 19039608 DOI: 10.1007/s00894-008-0410-0  0.64
2009 Salsbury FR, Crowder MW, Kingsmore SF, Huntley JJ. Molecular dynamic simulations of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor. Journal of Molecular Modeling. 15: 133-45. PMID 19039608 DOI: 10.1007/s00894-008-0410-0  0.64
2009 Limphong P, Crowder MW, Bennett B, Makaroff CA. Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2 Biochemical Journal. 417: 323-330. PMID 18782082 DOI: 10.1042/BJ20081151  0.64
2009 Gunasekera T, Easton JA, Sugerbaker SA, Klingbeil L, Crowder MW. Zn(II) homeostasis in E. coli Acs Symposium Series. 1012: 81-95. DOI: 10.1021/bk-2009-1012.ch006  0.64
2009 Gunasekera T, Easton JA, Sugerbaker SA, Klingbeil L, Crowder MW. Zn(II) homeostasis in E. coli Acs Symposium Series. 1012: 81-95. DOI: 10.1021/bk-2009-1012.ch006  0.36
2008 Hu Z, Periyannan G, Bennett B, Crowder MW. Role of the Zn1 and Zn2 sites in metallo-β- lactamase L1 Journal of the American Chemical Society. 130: 14207-14216. PMID 18831550 DOI: 10.1021/ja8035916  0.64
2008 Holdorf MM, Bennett B, Crowder MW, Makaroff CA. Spectroscopic studies on Arabidopsis ETHE1, a glyoxalase II-like protein Journal of Inorganic Biochemistry. 102: 1825-1830. PMID 18656261 DOI: 10.1016/j.jinorgbio.2008.06.003  0.64
2008 Hu Z, Gunasekera TS, Spadafora L, Bennett B, Crowder MW. Metal content of metallo-β-lactamase L1 is determined by the bioavailability of metal ions Biochemistry. 47: 7947-7953. PMID 18597493 DOI: 10.1021/bi8004768  0.64
2008 Sharma N, Hu Z, Crowder MW, Bennett B. Conformational changes in the metallo-β-lactamase ImiS during the catalytic reaction: An EPR spectrokinetic study of Co(II)-spin label interactions Journal of the American Chemical Society. 130: 8215-8222. PMID 18528987 DOI: 10.1021/ja0774562  0.64
2008 Hu Z, Periyannan GR, Crowder MW. Folding strategy to prepare Co(II)-substituted metallo-β-lactamase L1 Analytical Biochemistry. 378: 177-183. PMID 18445468 DOI: 10.1016/j.ab.2008.04.007  0.64
2008 Yatsunyk LA, Easton JA, Kim LR, Sugarbaker SA, Bennett B, Breece RM, Vorontsov II, Tierney DL, Crowder MW, Rosenzweig AC. Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 271-88. PMID 18027003 DOI: 10.1007/s00775-007-0320-0  0.64
2008 Yatsunyk LA, Easton JA, Kim LR, Sugarbaker SA, Bennett B, Breece RM, Vorontsov II, Tierney DL, Crowder MW, Rosenzweig AC. Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 271-88. PMID 18027003 DOI: 10.1007/s00775-007-0320-0  0.64
2008 Hu Z, Periyannan G, Bennett B, Crowder MW, Ezeh VC, Harrop TC. Role of the zn 1 and zn 2 sites in metallo-b̃- lactamase l1 Chemtracts. 21: 350-363.  0.64
2008 Hu Z, Periyannan G, Bennett B, Crowder MW, Ezeh VC, Harrop TC. Role of the zn 1 and zn 2 sites in metallo-b̃- lactamase l1 Chemtracts. 21: 350-363.  0.44
2007 Crisp J, Conners R, Garrity JD, Carenbauer AL, Crowder MW, Spencer J. Structural basis for the role of Asp-120 in metallo-β-lactamases Biochemistry. 46: 10664-10674. PMID 17715946 DOI: 10.1021/bi700707u  0.64
2006 Allen Easton J, Thompson P, Crowder MW. Time-dependent translational response of E. coli to excess Zn(II) Journal of Biomolecular Techniques. 17: 303-307. PMID 17122063  0.64
2006 Costello AL, Sharma NP, Yang KW, Crowder MW, Tierney DL. X-ray absorption spectroscopy of the zinc-binding sites in the class B2 metallo-beta-lactamase ImiS from Aeromonas veronii bv. sobria. Biochemistry. 45: 13650-8. PMID 17087519 DOI: 10.1021/bi061547e  0.64
2006 Costello AL, Sharma NP, Yang KW, Crowder MW, Tierney DL. X-ray absorption spectroscopy of the zinc-binding sites in the class B2 metallo-beta-lactamase ImiS from Aeromonas veronii bv. sobria. Biochemistry. 45: 13650-8. PMID 17087519 DOI: 10.1021/bi061547e  0.64
2006 Crowder MW, Spencer J, Vila AJ. Metallo-β-lactamases: Novel weaponry for antibiotic resistance in bacteria Accounts of Chemical Research. 39: 721-728. PMID 17042472 DOI: 10.1021/ar0400241  0.64
2006 Matthews ML, Periyannan G, Hajdin C, Sidgel TK, Bennett B, Crowder MW. Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme Journal of the American Chemical Society. 128: 13050-13051. PMID 17017774 DOI: 10.1021/ja0627343  0.64
2006 Sigdel TK, Easton JA, Crowder MW. Transcriptional response of Escherichia coli to TPEN Journal of Bacteriology. 188: 6709-6713. PMID 16952965 DOI: 10.1128/JB.00680-06  0.64
2006 Sharma NP, Hajdin C, Chandrasekar S, Bennett B, Yang KW, Crowder MW. Mechanistic studies on the mononuclear ZnII-containing metallo-β-lactamase ImiS from Aeromonas sobria Biochemistry. 45: 10729-10738. PMID 16939225 DOI: 10.1021/bi060893t  0.64
2006 Sigdel TK, Cilliers R, Gursahaney PR, Thompson P, Easton JA, Crowder MW. Probing the adaptive response of Escherichia coli to extracellular Zn(II) Biometals. 19: 461-471. PMID 16937252 DOI: 10.1007/s10534-005-4962-5  0.64
2006 Sun Q, Law A, Crowder MW, Geysen HM. Homo-cysteinyl peptide inhibitors of the L1 metallo-β-lactamase, and SAR as determined by combinatorial library synthesis Bioorganic and Medicinal Chemistry Letters. 16: 5169-5175. PMID 16875814 DOI: 10.1016/j.bmcl.2006.07.001  0.64
2006 Crowder MW. Combating vancomycin resistance in bacteria: Targeting the D-ala-D-ala dipeptidase Vanx Infectious Disorders - Drug Targets. 6: 147-158. PMID 16789876 DOI: 10.2174/187152606784112146  0.64
2006 Costello A, Periyannan G, Yang KW, Crowder MW, Tierney DL. Site-selective binding of Zn(II) to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 351-8. PMID 16489411 DOI: 10.1007/s00775-006-0083-z  0.64
2006 Costello A, Periyannan G, Yang KW, Crowder MW, Tierney DL. Site-selective binding of Zn(II) to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 351-8. PMID 16489411 DOI: 10.1007/s00775-006-0083-z  0.64
2006 Periyannan GR, Costello AL, Tierney DL, Yang KW, Bennett B, Crowder MW. Sequential binding of cobalt(II) to metallo-beta-lactamase CcrA. Biochemistry. 45: 1313-20. PMID 16430228 DOI: 10.1021/bi051105n  0.64
2006 Golich FC, Han M, Crowder MW. Over-expression, purification, and characterization of aminopeptidase N from Escherichia coli Protein Expression and Purification. 47: 634-639. PMID 16380266 DOI: 10.1016/j.pep.2005.11.012  0.64
2005 Marasinghe GPK, Sander IM, Bennett B, Periyannan G, Yang KW, Makaroff CA, Crowder MW. Structural studies on a mitochondrial glyoxalase II Journal of Biological Chemistry. 280: 40668-40675. PMID 16227621 DOI: 10.1074/jbc.M509748200  0.64
2005 Yang KW, Golich FC, Sigdel TK, Crowder MW. Phosphinate, sulfonate, and sulfonamidate dipeptides as potential inhibitors of Escherichia coli aminopeptidase N Bioorganic and Medicinal Chemistry Letters. 15: 5150-5153. PMID 16168644 DOI: 10.1016/j.bmcl.2005.08.055  0.64
2005 Crawford PA, Yang KW, Sharma N, Bennett B, Crowder MW. Spectroscopic studies on cobalt(II)-substituted metallo-β-lactamase ImiS from Aeromonas veronii bv. sobria Biochemistry. 44: 5168-5176. PMID 15794654 DOI: 10.1021/bi047463s  0.64
2005 Breece RM, Costello A, Bennett B, Sigdel TK, Matthews ML, Tierney DL, Crowder MW. A five-coordinate metal center in Co(II)-substituted VanX. The Journal of Biological Chemistry. 280: 11074-81. PMID 15657055 DOI: 10.1074/jbc.M412582200  0.64
2005 Breece RM, Costello A, Bennett B, Sigdel TK, Matthews ML, Tierney DL, Crowder MW. A five-coordinate metal center in Co(II)-substituted VanX. The Journal of Biological Chemistry. 280: 11074-81. PMID 15657055 DOI: 10.1074/jbc.M412582200  0.64
2005 Garrity JD, Bennett B, Crowder MW. Direct evidence that the reaction intermediate of metallo-β-lactamase L1 is metal bound Biochemistry. 44: 1078-1087. PMID 15654764 DOI: 10.1021/bi048385b  0.64
2004 Sigdel TK, Cilliers R, Gursahaney PR, Crowder MW. Fractionation of soluble proteins in Escherichia coli using DEAE-, SP-, and phenyl sepharose chromatographies Journal of Biomolecular Techniques. 15: 199-207. PMID 15331586  0.64
2004 Garrity JD, Pauff JM, Crowder MW. Probing the dynamics of a mobile loop above the active site of L1, metallo-β-lactamase from Stenotrophomonas maltophilia, via site-directed mutagenesis and stopped-flow fluorescence spectroscopy Journal of Biological Chemistry. 279: 39663-39670. PMID 15271998 DOI: 10.1074/jbc.M406826200  0.64
2004 Golich FC, Sigdel T, Breece RM, Detar L, Herron LR, Crowder MW. L-Alanine-p-nitroanilide is not a substrate for VanX Analytical Biochemistry. 331: 398-400. PMID 15265748 DOI: 10.1016/j.ab.2004.05.026  0.64
2004 Crawford PA, Sharma N, Chandrasekar S, Sigdel T, Walsh TR, Spencer J, Crowder MW. Over-expression, purification, and characterization of metallo-β- lactamase ImiS from Aeromonas veronii bv. sobria Protein Expression and Purification. 36: 272-279. PMID 15249050 DOI: 10.1016/j.pep.2004.04.017  0.64
2004 Periyannan G, Shaw PJ, Sigdel T, Crowder MW. In vivo folding of recombinant metallo-β-lactamase L1 requires the presence of Zn(II) Protein Science. 13: 2236-2243. PMID 15238636 DOI: 10.1110/ps.04742704  0.64
2004 Yang KW, Crowder MW. A method for removing ethylenediaminetetraacetic acid from apo-proteins Analytical Biochemistry. 329: 342-344. PMID 15158498 DOI: 10.1016/j.ab.2004.03.027  0.64
2004 Wenzel NF, Carenbauer AL, Pfiester MP, Schilling O, Meyer-Klaucke W, Makaroff CA, Crowder MW. The binding of iron and zinc to glyoxalase II occurs exclusively as di-metal centers and is unique within the metallo-β-lactamase family Journal of Biological Inorganic Chemistry. 9: 429-438. PMID 15067523 DOI: 10.1007/s00775-004-0535-2  0.64
2004 Garrity JD, Carenbauer AL, Herron LR, Crowder MW. Metal Binding Asp-120 in Metallo-β-lactamase L1 from Stenotrophomonas maltophilia Plays a Crucial Role in Catalysis Journal of Biological Chemistry. 279: 920-927. PMID 14573595 DOI: 10.1074/jbc.M309852200  0.64
2003 Cao X, Iqbal A, Patel A, Gretz P, Huang G, Crowder M, Day RA. 3-alkoxy-5-isoxazolidinones mimic beta-lactams. Biochemical and Biophysical Research Communications. 311: 267-71. PMID 14592409 DOI: 10.1016/j.bbrc.2003.09.210  0.64
2003 Schilling O, Wenzel N, Naylor M, Vogel A, Crowder M, Makaroff C, Meyer-Klaucke W. Flexible metal binding of the metallo-β-lactamase domain: Glyoxalase II incorporates iron, manganese, and zinc in vivo Biochemistry. 42: 11777-11786. PMID 14529289 DOI: 10.1021/bi034672o  0.64
2003 Yang KW, Sobieski DN, Carenbauer AL, Crawford PA, Makaroff CA, Crowder MW. Explaining the inhibition of glyoxalase II by 9-fluorenylmethoxycarbonyl-protected glutathione derivatives Archives of Biochemistry and Biophysics. 414: 271-278. PMID 12781779 DOI: 10.1016/S0003-9861(03)00193-0  0.64
2003 Jacquamet L, Sun Y, Hatfield J, Gu W, Cramer SP, Crowder MW, Lorigan GA, Vincent JB, Latour JM. Characterization of chromodulin by X-ray absorption and electron paramagnetic resonance spectroscopies and magnetic susceptibility measurements Journal of the American Chemical Society. 125: 774-780. PMID 12526678 DOI: 10.1021/ja0202661  0.64
2003 Jacquamet L, Sun Y, Hatfield J, Gu W, Cramer SP, Crowder MW, Lorigan GA, Vincent JB, Latour JM. Characterization of chromodulin by X-ray absorption and electron paramagnetic resonance spectroscopies and magnetic susceptibility measurements Journal of the American Chemical Society. 125: 774-780. PMID 12526678 DOI: 10.1021/ja0202661  0.64
2002 Simm AM, Higgins CS, Carenbauer AL, Crowder MW, Bateson JH, Bennett PM, Clarke AR, Halford SE, Walsh TR. Characterization of monomeric L1 metallo-β-lactamase and the role of the N-terminal extension in negative cooperativity and antibiotic hydrolysis Journal of Biological Chemistry. 277: 24744-24752. PMID 11940588 DOI: 10.1074/jbc.M201524200  0.64
2002 Carenbauer AL, Garrity JD, Periyannan G, Yates RB, Crowder MW. Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis. Bmc Biochemistry [Electronic Resource]. 3: 4. PMID 11876827 DOI: 10.1186/1471-2091-3-4  0.64
2002 Carenbauer AL, Garrity JD, Periyannan G, Yates RB, Crowder MW. Probing substrate binding to metallo-β-lactamase L1 fromStenotrophomonas maltophilia by using site-directed mutagenesis Bmc Biochemistry. 3: 1-13. DOI: 10.1186/1471-2091-3-1  0.56
2002 Carenbauer AL, Garrity JD, Periyannan G, Yates RB, Crowder MW. Probing substrate binding to metallo-β-lactamase L1 fromStenotrophomonas maltophilia by using site-directed mutagenesis Bmc Biochemistry. 3: 1-13. DOI: 10.1186/1471-2091-3-1  0.56
2001 Crowder MW, Yang KW, Carenbauer AL, Periyannan G, Seifert ME, Rude NE, Walsh TR. The problem of a solvent exposable disulfide when preparing Co(II)-substituted metallo-β-lactamase L1 from Stenotrophomonas maltophilia Journal of Biological Inorganic Chemistry. 6: 91-99. PMID 11191226 DOI: 10.1007/s007750000173  0.64
2001 Zang TM, Hollman DA, Crawford PA, Crowder MW, Makaroff CA. Arabidopsis Glyoxalase II Contains a Zinc/Iron Binuclear Metal Center That Is Essential for Substrate Binding and Catalysis Journal of Biological Chemistry. 276: 4788-4795. PMID 11085979 DOI: 10.1074/jbc.M005090200  0.64
2000 Brandt JJ, Chatwood LL, Crowder MW. Analysis of three overexpression systems for VanX, the zinc(II) dipeptidase required for high-level vancomycin resistance in bacteria Protein Expression and Purification. 20: 300-307. PMID 11049753 DOI: 10.1006/prep.2000.1303  0.64
2000 Yanchak MP, Taylor RA, Crowder MW. Mutational analysis of metallo-β-lactamase CcrA from Bacteroides fragilis Biochemistry. 39: 11330-11339. PMID 10985778 DOI: 10.1021/bi0010524  0.64
2000 Yang KW, Brandt JJ, Chatwood LL, Crowder MW. Phosphonamidate and phosphothioate dipeptides as potential inhibitors of VanX Bioorganic and Medicinal Chemistry Letters. 10: 1085-1087. PMID 10843223 DOI: 10.1016/S0960-894X(00)00186-4  0.64
1999 Yang KW, Crowder MW. Inhibition studies on the metallo-β-lactamase L1 from Stenotrophomonas maltophilia Archives of Biochemistry and Biophysics. 368: 1-6. PMID 10415104 DOI: 10.1006/abbi.1999.1293  0.64
1999 Brandt JJ, Chatwood LL, Yang KW, Crowder MW. Continuous assay for VanX, the D-alanyl-D-alanine dipeptidase required for high-level vancomycin resistance Analytical Biochemistry. 272: 94-99. PMID 10405298 DOI: 10.1006/abio.1999.4166  0.64
1999 McManus-Munoz S, Crowder MW. Kinetic mechanism of metallo-β-lactamase L1 from stenotrophomonas maltophilia Biochemistry. 38: 1547-1553. PMID 9931021 DOI: 10.1021/bi9826512  0.64
1999 Crowder MW, Numan AQ, Haddadian F, Weitzel MA, Danielson ND. Capillary electrophoresis of phosphoamino acids with indirect photometric detection Analytica Chimica Acta. 384: 127-133. DOI: 10.1016/S0003-2670(98)00810-1  0.64
1999 Speetjens JK, Parand A, Crowder MW, Vincent JB, Woski SA. Low-molecular-weight chromium-binding substance and biomimetic [Cr3O(O2CCH2CH3)6(H 2O)3]+ do not cleave DNA under physiologically-relevant conditions Polyhedron. 18: 2617-2624.  0.64
1999 Speetjens JK, Parand A, Crowder MW, Vincent JB, Woski SA. Low-molecular-weight chromium-binding substance and biomimetic [Cr3O(O2CCH2CH3)6(H 2O)3]+ do not cleave DNA under physiologically-relevant conditions Polyhedron. 18: 2617-2624.  0.6
1998 Crowder MW, Walsh TR, Banovic L, Pettit M, Spencer J. Overexpression, purification, and characterization of the cloned metallo-β-lactamase L1 from Stenotrophomonas maltophilia Antimicrobial Agents and Chemotherapy. 42: 921-926. PMID 9559809  0.64
1998 Parana A, Royer AC, Cantrell TL, Weitzel M, Memon N, Vincent JB, Crowder MW. DNA nicking by a trinuclear chromium complex Inorganica Chimica Acta. 268: 211-219.  0.64
1998 Parana A, Royer AC, Cantrell TL, Weitzel M, Memon N, Vincent JB, Crowder MW. DNA nicking by a trinuclear chromium complex Inorganica Chimica Acta. 268: 211-219.  0.6
1997 Crowder MW, Maiti MK, Banovic L, Makaroff CA. Glyoxalase II from A. thialana requires Zn(II) for catalytic activity Febs Letters. 418: 351-354. PMID 9428743 DOI: 10.1016/S0014-5793(97)01416-6  0.64
1996 Crowder MW, Wang Z, Franklin SL, Zovinka EP, Benkovic SJ. Characterization of the metal-binding sites of the beta-lactamase from Bacteroides fragilis. Biochemistry. 35: 12126-32. PMID 8810919 DOI: 10.1021/bi960976h  0.64
1996 Crowder MW, Wang Z, Franklin SL, Zovinka EP, Benkovic SJ. Characterization of the metal-binding sites of the beta-lactamase from Bacteroides fragilis. Biochemistry. 35: 12126-32. PMID 8810919 DOI: 10.1021/bi960976h  0.64
1995 Crowder MW, Stewart JD, Roberts VA, Bender CJ, Tevelrakh E, Peisach J, Getzoff ED, Gaffney BJ, Benkovic SJ. Spectroscopic studies on the designed metal-binding sites of the 43C9 single chain antibody Journal of the American Chemical Society. 117: 5627-5634.  0.64
1995 Crowder MW, Stewart JD, Roberts VA, Bender CJ, Tevelrakh E, Peisach J, Getzoff ED, Gaffney BJ, Benkovic SJ. Spectroscopic studies on the designed metal-binding sites of the 43C9 single chain antibody Journal of the American Chemical Society. 117: 5627-5634.  0.64
1994 Stewart JD, Roberts VA, Crowder MW, Getzoff ED, Benkovic SJ. Creation of a novel biosensor for Zn(II) Journal of the American Chemical Society. 116: 415-416.  0.64
1994 Stewart JD, Roberts VA, Crowder MW, Getzoff ED, Benkovic SJ. Creation of a novel biosensor for Zn(II) Journal of the American Chemical Society. 116: 415-416.  0.32
1992 Wang Z, Ming LJ, Que L, Vincent JB, Crowder MW, Averill BA. 1H NMR and NOE studies of the purple acid phosphatases from porcine uterus and bovine spleen. Biochemistry. 31: 5263-8. PMID 1606150  0.64
1992 Vincent JB, Crowder MW, Averill BA. Hydrolysis of phosphate monoesters: a biological problem with multiple chemical solutions. Trends in Biochemical Sciences. 17: 105-10. PMID 1412693 DOI: 10.1016/0968-0004(92)90246-6  0.64
1992 Vincent JB, Crowder MW, Averill BA. Multiple binding sites for tetrahedral oxyanion inhibitors of bovine spleen purple acid phosphatase. Biochemistry. 31: 3033-7. PMID 1372824  0.64
1992 Vincent JB, Crowder MW, Averill BA. Multiple binding sites for tetrahedral oxyanion inhibitors of bovine spleen purple acid phosphatase. Biochemistry. 31: 3033-7. PMID 1372824  0.64
1992 Crowder MW, Vincent JB, Averill BA. Electron paramagnetic resonance studies on the high-salt form of bovine spleen purple acid phosphatase. Biochemistry. 31: 9603-8. PMID 1327121  0.64
1992 Crowder MW, Vincent JB, Averill BA. Electron paramagnetic resonance studies on the high-salt form of bovine spleen purple acid phosphatase. Biochemistry. 31: 9603-8. PMID 1327121  0.64
1991 Vincent JB, Crowder MW, Averill BA. Evidence for a phosphoryl-enzyme intermediate in phosphate ester hydrolysis by purple acid phosphatase from bovine spleen. The Journal of Biological Chemistry. 266: 17737-40. PMID 1917918  0.64
1991 Vincent JB, Crowder MW, Averill BA. Evidence for a phosphoryl-enzyme intermediate in phosphate ester hydrolysis by purple acid phosphatase from bovine spleen. The Journal of Biological Chemistry. 266: 17737-40. PMID 1917918  0.64
1991 Vincent JB, Crowder MW, Averill BA. Spectroscopic and kinetics studies of a high-salt-stabilized form of the purple acid phosphatase from bovine spleen. Biochemistry. 30: 3025-34. PMID 1848783  0.64
1991 Vincent JB, Crowder MW, Averill BA. Spectroscopic and kinetics studies of a high-salt-stabilized form of the purple acid phosphatase from bovine spleen. Biochemistry. 30: 3025-34. PMID 1848783  0.64
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