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Sean W. Fanning, Ph.D. - Publications

Affiliations: 
2012 Chemistry and Biochemistry Northern Illinois University, DeKalb, IL, United States 
Area:
Biochemistry, Biomedical Engineering
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19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Speltz TE, Qiao Z, Swenson CS, Shangguan X, Coukos JS, Lee CW, Thomas DM, Santana J, Fanning SW, Greene GL, Moellering RE. Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. Nature Biotechnology. PMID 36302987 DOI: 10.1038/s41587-022-01504-x  0.335
2020 Fanning SW, Greene G, Conlan MG. X-ray crystal structure analysis of elacestrant (RAD1901), a novel selective estrogen receptor degrader (SERD), bound to estrogen receptor alpha ligand binding domain. Journal of Clinical Oncology. 38: e15647-e15647. DOI: 10.1200/Jco.2020.38.15_Suppl.E15647  0.427
2020 Ren P, Fanning SW, Tiede C, Adams TL, Speirs V, Greene GL, Nelson ER, Tomlinson DC, Selvin PR. Efficient Labeling of Estrogen Receptor α Inside Cells using Affimer, an Antibody Mimetic Biophysical Journal. 118: 470a. DOI: 10.1016/J.Bpj.2019.11.2607  0.32
2019 Montgomery JE, Donnelly JA, Fanning SW, Speltz TE, Shangguan X, Coukos JS, Greene GL, Moellering RE. Versatile peptide macrocyclization with Diels-Alder cycloadditions. Journal of the American Chemical Society. PMID 31523967 DOI: 10.1021/Jacs.9B07578  0.36
2019 Fanning S, Laine M, Greene M, Chang Y, Phung L, Green B, Hiipakka R, Han R, Komm B, Greene G. SUN-006 Lasofoxifene Achieves Potent Anti-Tumor Activity in Hormone-Resistant Breast Tumors by Maintaining High Affinity Binding for Y537S ERα Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-006  0.332
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/Elife.37161  0.305
2018 Fanning SW, Hodges-Gallagher L, Myles DC, Sun R, Fowler CE, Plant IN, Green BD, Harmon CL, Greene GL, Kushner PJ. Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nature Communications. 9: 2368. PMID 29915250 DOI: 10.1038/S41467-018-04413-3  0.304
2018 Speltz TE, Mayne CG, Fanning SW, Siddiqui Z, Tajkhorshid E, Greene GL, Moore TW. A "cross-stitched" peptide with improved helicity and proteolytic stability. Organic & Biomolecular Chemistry. PMID 29725689 DOI: 10.1039/C8Ob00790J  0.318
2018 Speltz TE, Danes JM, Fanning SW, Mayne CG, Tajkhorshid E, Greene GL, Frasor JM, Moore TW. Abstract 1810: Stapled peptide inhibitors of mutant estrogen receptor/coactivator interactions Cancer Research. 78: 1810-1810. DOI: 10.1158/1538-7445.Am2018-1810  0.334
2016 Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, et al. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife. 5. PMID 26836308 DOI: 10.7554/Elife.12792  0.37
2016 Moore TW, Speltz TE, Fanning SW, Mayne CG, Frasor J, Greene GL, Tajkhorshid E. Abstract 3104: Stapled peptide inhibitors of the estrogen receptor/steroid receptor coactivator interaction Cancer Research. 76: 3104-3104. DOI: 10.1158/1538-7445.Am2016-3104  0.325
2015 Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07  0.315
2015 Horn JR, Murtaugh ML, Fanning SW, Smith CA, Griffin DH. Remodeling Protein Interfaces to Regulate Recognition Biophysical Journal. 108: 627a-628a. DOI: 10.1016/J.Bpj.2014.11.3412  0.665
2014 Fanning SW, Walter R, Horn JR, Tawfik D. Structural basis of an engineered dual-specific antibody: Conformational diversity leads to a hypervariable loop metal-binding site Protein Engineering, Design and Selection. 27: 391-397. PMID 25143596 DOI: 10.1093/Protein/Gzu033  0.77
2013 Toy W, Shen Y, Won H, Green B, Sakr RA, Will M, Li Z, Gala K, Fanning S, King TA, Hudis C, Chen D, Taran T, Hortobagyi G, Greene G, et al. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nature Genetics. 45: 1439-45. PMID 24185512 DOI: 10.1038/Ng.2822  0.347
2012 Sztuba-Solińska J, Fanning SW, Horn JR, Bujarski JJ. Mutations in the coat protein-binding cis-acting RNA motifs debilitate RNA recombination of Brome mosaic virus. Virus Research. 170: 138-49. PMID 23079110 DOI: 10.1016/J.Virusres.2012.10.001  0.668
2011 Murtaugh ML, Fanning SW, Sharma TM, Terry AM, Horn JR. A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switches. Protein Science : a Publication of the Protein Society. 20: 1619-31. PMID 21766385 DOI: 10.1002/Pro.696  0.666
2011 Fanning SW, Murtaugh ML, Horn JR. A combinatorial approach to engineering a dual-specific metal switch antibody. Biochemistry. 50: 5093-5. PMID 21568282 DOI: 10.1021/Bi2003845  0.655
2011 Fanning SW, Horn JR. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Science : a Publication of the Protein Society. 20: 1196-207. PMID 21557375 DOI: 10.1002/Pro.648  0.744
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