Keith E. Shearwin - Publications

University of Adelaide, Adelaide, South Australia, Australia 
Gene regulation mechanisms, phage

60/74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hao N, Sullivan AE, Shearwin KE, Dodd IB. The loopometer: a quantitative in vivo assay for DNA-looping proteins. Nucleic Acids Research. PMID 33511418 DOI: 10.1093/nar/gkaa1284  0.68
2020 Murchland IM, Ahlgren-Berg A, Pietsch JMJ, Isabel A, Dodd IB, Shearwin KE. Instability of CII is needed for efficient switching between lytic and lysogenic development in bacteriophage 186. Nucleic Acids Research. 48: 12030-12041. PMID 33211866 DOI: 10.1093/nar/gkaa1065  0.68
2020 Cutts EE, Barry Egan J, Dodd IB, Shearwin KE. A quantitative binding model for the Apl protein, the dual purpose recombination-directionality factor and lysis-lysogeny regulator of bacteriophage 186. Nucleic Acids Research. PMID 32789491 DOI: 10.1093/Nar/Gkaa655  0.68
2019 Hao N, Crooks MT, Palmer AC, Dodd IB, Shearwin KE. RNA polymerase pausing at a protein roadblock can enhance transcriptional interference by promoter occlusion. Febs Letters. PMID 30892685 DOI: 10.1002/1873-3468.13365  0.68
2019 Hao N, Shearwin KE, Dodd IB. Positive and Negative Control of Enhancer-Promoter Interactions by Other DNA Loops Generates Specificity and Tunability. Cell Reports. 26: 2419-2433.e3. PMID 30811991 DOI: 10.1016/J.Celrep.2019.02.002  0.68
2017 Hao N, Shearwin KE, Dodd IB. Programmable DNA looping using engineered bivalent dCas9 complexes. Nature Communications. 8: 1628. PMID 29158476 DOI: 10.1038/S41467-017-01873-X  0.68
2017 Hao N, Sneppen K, Shearwin KE, Dodd IB. Efficient chromosomal-scale DNA looping in Escherichia coli using multiple DNA-looping elements. Nucleic Acids Research. PMID 28160597 DOI: 10.1093/Nar/Gkx069  0.68
2017 Hao N, Palmer AC, Dodd IB, Shearwin KE. Directing traffic on DNA - How transcription factors relieve or induce transcriptional interference. Transcription. 0. PMID 28129043 DOI: 10.1080/21541264.2017.1285851  0.68
2017 Cui L, Shearwin KE. Clonetegration Using OSIP Plasmids: One-Step DNA Assembly and Site-Specific Genomic Integration in Bacteria. Methods in Molecular Biology (Clifton, N.J.). 1472: 139-55. PMID 27671938 DOI: 10.1007/978-1-4939-6343-0_11  1
2016 Munro PD, Ackers GK, Shearwin KE. Aspects of protein-DNA interactions: a review of quantitative thermodynamic theory for modelling synthetic circuits utilising LacI and CI repressors, IPTG and the reporter gene lacZ. Biophysical Reviews. 8: 331-345. PMID 28510022 DOI: 10.1007/S12551-016-0231-9  0.44
2016 Hao N, Palmer AC, Ahlgren-Berg A, Shearwin KE, Dodd IB. The role of repressor kinetics in relief of transcriptional interference between convergent promoters. Nucleic Acids Research. PMID 27378773 DOI: 10.1093/Nar/Gkw600  0.68
2014 Murchland I, Ahlgren-Berg A, Priest DG, Dodd IB, Shearwin KE. Promoter activation by CII, a potent transcriptional activator from bacteriophage 186 Journal of Biological Chemistry. 289: 32094-32108. PMID 25294872 DOI: 10.1074/Jbc.M114.608026  1
2014 Priest DG, Kumar S, Yan Y, Dunlap DD, Dodd IB, Shearwin KE. Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E4449-57. PMID 25288735 DOI: 10.1073/Pnas.1410764111  0.68
2014 Hao N, Krishna S, Ahlgren-Berg A, Cutts EE, Shearwin KE, Dodd IB. Road rules for traffic on DNA-systematic analysis of transcriptional roadblocking in vivo. Nucleic Acids Research. 42: 8861-72. PMID 25034688 DOI: 10.1093/Nar/Gku627  1
2014 Priest DG, Cui L, Kumar S, Dunlap DD, Dodd IB, Shearwin KE. Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors Proceedings of the National Academy of Sciences of the United States of America. 111: 349-354. PMID 24344307 DOI: 10.1073/Pnas.1317817111  1
2014 Priest DG, Kumar S, Yan Y, Dunlap DD, Dodd IB, Shearwin KE. Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells Proceedings of the National Academy of Sciences of the United States of America. 111: E4449-E4457. DOI: 10.1073/pnas.1410764111  1
2013 Cui L, St-Pierre F, Shearwin K. Repurposing site-specific recombinases for synthetic biology Future Microbiology. 8: 1361-1364. PMID 24199794 DOI: 10.2217/Fmb.13.119  1
2013 St-Pierre F, Cui L, Priest DG, Endy D, Dodd IB, Shearwin KE. One-step cloning and chromosomal integration of DNA Acs Synthetic Biology. 2: 537-541. PMID 24050148 DOI: 10.1021/Sb400021J  1
2013 Cui L, Murchland I, Dodd IB, Shearwin KE. Bacteriophage lambda repressor mediates the formation of a complex enhancer-like structure Transcription. 4. PMID 23989664 DOI: 10.4161/trns.26101  1
2013 Gao N, Shearwin K, Mack J, Finzi L, Dunlap D. Purification of bacteriophage lambda repressor Protein Expression and Purification. 91: 30-36. PMID 23831434 DOI: 10.1016/J.Pep.2013.06.013  1
2013 Wang H, Dodd IB, Dunlap DD, Shearwin KE, Finzi L. Single molecule analysis of DNA wrapping and looping by a circular 14mer wheel of the bacteriophage 186 CI repressor Nucleic Acids Research. 41: 5746-5756. PMID 23620280 DOI: 10.1093/Nar/Gkt298  1
2013 Cui L, Murchland I, Shearwin KE, Dodd IB. Enhancer-like long-range transcriptional activation by λ CI-mediated DNA looping Proceedings of the National Academy of Sciences of the United States of America. 110: 2922-2927. PMID 23382214 DOI: 10.1073/Pnas.1221322110  1
2011 Palmer AC, Egan JB, Shearwin KE. Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors. Transcription. 2: 9-14. PMID 21326903 DOI: 10.4161/trns.2.1.13511  1
2011 Hao N, Whitelaw ML, Shearwin KE, Dodd IB, Chapman-Smith A. Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR Nucleic Acids Research. 39: 3695-3709. PMID 21245039 DOI: 10.1093/Nar/Gkq1336  1
2009 Shearwin K. Slow growth leads to a switch Nature Chemical Biology. 5: 784-785. PMID 19841626 DOI: 10.1038/Nchembio.248  1
2009 Palmer AC, Ahlgren-Berg A, Egan JB, Dodd IB, Shearwin KE. Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter. Molecular Cell. 34: 545-55. PMID 19524535 DOI: 10.1016/J.Molcel.2009.04.018  1
2009 Palmer AC, Shearwin KE. Guidance for data collection and computational modelling of regulatory networks. Methods in Molecular Biology (Clifton, N.J.). 541: 337-354. PMID 19381541 DOI: 10.1007/978-1-59745-243-4_15  1
2007 Schubert RA, Dodd IB, Egan JB, Shearwin KE. Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic development. Genes & Development. 21: 2461-72. PMID 17908932 DOI: 10.1101/Gad.1584907  1
2007 Dodd IB, Shearwin KE, Sneppen K. Modelling Transcriptional Interference and DNA Looping in Gene Regulation Journal of Molecular Biology. 369: 1200-1213. PMID 17498740 DOI: 10.1016/j.jmb.2007.04.041  1
2006 Pinkett HW, Shearwin KE, Stayrook S, Dodd IB, Burr T, Hochschild A, Egan JB, Lewis M. The structural basis of cooperative regulation at an alternate genetic switch Molecular Cell. 21: 605-615. PMID 16507359 DOI: 10.1016/J.Molcel.2006.01.019  1
2005 Trusina A, Sneppen K, Dodd IB, Shearwin KE, Egan JB. Functional alignment of regulatory networks: a study of temperate phages. Plos Computational Biology. 1: e74. PMID 16477325 DOI: 10.1371/Journal.Pcbi.0010074  1
2005 Shearwin KE, Callen BP, Egan JB. Transcriptional interference - A crash course Trends in Genetics. 21: 339-345. PMID 15922833 DOI: 10.1016/J.Tig.2005.04.009  1
2005 Dodd IB, Shearwin KE, Egan JB. Revisited gene regulation in bacteriophage λ Current Opinion in Genetics and Development. 15: 145-152. PMID 15797197 DOI: 10.1016/J.Gde.2005.02.001  1
2005 Sneppen K, Dodd IB, Shearwin KE, Palmer AC, Schubert RA, Callen BP, Egan JB. A mathematical model for transcriptional interference by RNA polymerase traffic in Escherichia coli Journal of Molecular Biology. 346: 399-409. PMID 15670592 DOI: 10.1016/J.Jmb.2004.11.075  1
2005 Trusma A, Sneppen K, Dodd IB, Shearwin KE, Barry Egan J. Functional Alignment of Regulatory Networks: A Study of Temperate Phages Plos Computational Biology. 1: 0599-0603. DOI: 10.1371/journal.pcbi.0010074  1
2004 Callen BP, Shearwin KE, Egan JB. Transcriptional interference between convergent promoters caused by elongation over the promoter Molecular Cell. 14: 647-656. PMID 15175159 DOI: 10.1016/J.Molcel.2004.05.010  1
2004 Dodd IB, Shearwin KE, Perkins AJ, Burr T, Hochschild A, Egan JB. Cooperativity in long-range gene regulation by the λ CI repressor Genes and Development. 18: 344-354. PMID 14871931 DOI: 10.1101/Gad.1167904  1
2003 Fotia AB, Dinudom A, Shearwin KE, Koch JP, Korbmacher C, Cook DI, Kumar S. The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels. The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 70-72. PMID 12424229 DOI: 10.1096/Fj.02-0497Fje  1
2002 Shearwin KE, Dodd IB, Barry Egan J. The helix-turn-helix motif of the coliphage 186 immunity repressor binds to two distinct recognition sequences Journal of Biological Chemistry. 277: 3186-3194. PMID 11700308 DOI: 10.1074/Jbc.M107740200  1
2001 Neufing PJ, Shearwin KE, Egan JB. Establishing lysogenic transcription in the temperate coliphage 186 Journal of Bacteriology. 183: 2376-2379. PMID 11244081 DOI: 10.1128/JB.183.7.2376-2379.2001  1
2000 Shearwin KE, Egan JB. Establishment of lysogeny in bacteriophage 186. DNA binding and transcriptional activation by the CII protein Journal of Biological Chemistry. 275: 29113-29122. PMID 10871623 DOI: 10.1074/Jbc.M004574200  1
1998 Shearwin KE, Brumby AM, Egan JB. The tum protein of coliphage 186 is an antirepressor Journal of Biological Chemistry. 273: 5708-5715. PMID 9488703 DOI: 10.1074/jbc.273.10.5708  1
1997 Reed MR, Shearwin KE, Pell LM, Egan JB. The dual role of Apl in prophage induction of coliphage 186 Molecular Microbiology. 23: 669-681. PMID 9157239 DOI: 10.1046/J.1365-2958.1997.2521620.X  1
1996 Neufing PJ, Shearwin KE, Camerotto J, Egan JB. The CII protein of bacteriophage 186 establishes lysogeny by activating a promoter upstream of the lysogenic promoter Molecular Microbiology. 21: 751-761. PMID 8878038 DOI: 10.1046/J.1365-2958.1996.351394.X  1
1996 Shearwin KE, Barry Egan J. Purification and self-association equilibria of the lysis-lysogeny switch proteins of coliphage 186 Journal of Biological Chemistry. 271: 11525-11531. PMID 8626713 DOI: 10.1074/jbc.271.19.11525  1
1994 Shearwin KE, Timasheff SN. Effect of colchicine analogues on the dissociation of alpha beta tubulin into subunits: the locus of colchicine binding. Biochemistry. 33: 894-901. PMID 8305437 DOI: 10.1021/Bi00170A007  1
1994 Shearwin KE, Perez-Ramirez B, Timasheff SN. Linkages between the dissociation of alpha beta tubulin into subunits and ligand binding: the ground state of tubulin is the GDP conformation. Biochemistry. 33: 885-93. PMID 8305436  1
1994 Perez-Ramirez B, Shearwin KE, Timasheff SN. The colchicine-induced GTPase activity of tubulin: state of the product. Activation by microtubule-promoting cosolvents. Biochemistry. 33: 6253-61. PMID 8193140 DOI: 10.1021/Bi00186A027  1
1994 Shearwin KE, Perez-Ramirez B, Timashef SN. Linkages between the dissociation of αβ tubulin into subunits and ligand binding: The ground state of tubulin is the GDP conformation Biochemistry. 33: 885-893.  1
1992 Shearwin KE, Timasheff SN. Linkage between ligand binding and control of tubulin conformation. Biochemistry. 31: 8080-9. PMID 1510990 DOI: 10.1021/Bi00149A044  1
1990 Shearwin KE, Winzor DJ. Thermodynamic nonideality in macromolecular solutions. Evaluation of parameters for the prediction of covolume effects. European Journal of Biochemistry. 190: 523-529. PMID 2373080 DOI: 10.1111/J.1432-1033.1990.Tb15605.X  1
1990 Shearwin KE, Winzor DJ. Effect of calcium ion on the dimerization of α-chymotrypsin Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1038: 136-138. PMID 2317514 DOI: 10.1016/0167-4838(90)90022-8  1
1990 Shearwin KE, Winzor DJ. Allowance for thermodynamic nonideality and Donnan effects in binding studies. Activity coefficients of charged ligands in the presence of albumin Biophysical Chemistry. 36: 235-243. PMID 2289023 DOI: 10.1016/0301-4622(90)80029-7  1
1990 Shearwin KE, Winzor DJ. Thermodynamic nonideality as a probe of reversible protein unfolding effected by variations in pH and temperature: Studies of ribonuclease Archives of Biochemistry and Biophysics. 282: 297-301. PMID 2241152 DOI: 10.1016/0003-9861(90)90120-N  1
1990 Shearwin K, Mazsters C. The binding of glycolytic enzymes to the cytoskeleton - influence of pH Biochemistry International. 22: 735-740. PMID 2150310  1
1990 Shearwin K, Nanhua C, Masters C. Interactions between glycolytic enzymes and cytoskeletal structure - The influence of ionic strength and molecular crowding Biochemistry International. 21: 53-60. PMID 2143653  1
1989 Bergman DA, Shearwin KE, Winzor DJ. Effects of thermodynamic nonideality on the kinetics of ester hydrolysis by α-chymotrypsin: A model system with preexistence of the isomerization equilibrium Archives of Biochemistry and Biophysics. 274: 55-63. PMID 2774582 DOI: 10.1016/0003-9861(89)90414-1  1
1989 Shearwin K, Nanhua C, Masters C. The influence of molecular crowding on the binding of glycolytic enzymes to cytoskeletal structure Biochemistry International. 19: 723-729. PMID 2619744  1
1988 Shearwin KE, Winzor DJ. Substrate as a source of thermodynamic nonideality in enzyme kinetic studies: Invertase-catalyzed hydrolysis of sucrose Archives of Biochemistry and Biophysics. 260: 532-539. PMID 3277534 DOI: 10.1016/0003-9861(88)90478-X  1
1988 Shearwin KE, Winzor DJ. Effect of sucrose on the dimerization of alpha-chymotrypsin. Allowance for thermodynamic nonideality arising from the presence of a small inert solute. Biophysical Chemistry. 31: 287-94. PMID 3233302 DOI: 10.1016/0301-4622(88)80034-6  1
Low-probability matches
2019 Hoffmann S, Hao N, Shearwin KE, Arndt KM. Characterizing transcriptional interference between converging genes in bacteria. Acs Synthetic Biology. PMID 30717589 DOI: 10.1021/Acssynbio.8B00477  0.24
2017 Hao N, Shearwin KE. Hidden Secrets of Sigma54 Promoters Revealed. Trends in Biochemical Sciences. PMID 29126750 DOI: 10.1016/J.Tibs.2017.10.005  0.24
2021 Truong JQ, Nguyen S, Bruning JB, Shearwin KE. Derivatization of Protein Crystals with I3C using Random Microseed Matrix Screening. Journal of Visualized Experiments : Jove. PMID 33522501 DOI: 10.3791/61894  0.01
2020 Hayes AJ, Satiaputra J, Sternicki LM, Paparella AS, Feng Z, Lee KJ, Rodriguez BB, Tieu W, Eijkelkamp BA, Shearwin KE, Pukala TL, Abell AD, Booker GW, Polyak SW. Advanced Resistance Studies Identify Two Discrete Mechanisms in to Overcome Antibacterial Compounds that Target Biotin Protein Ligase. Antibiotics (Basel, Switzerland). 9. PMID 32268615 DOI: 10.3390/Antibiotics9040165  0.01
2019 Truong JQ, Panjikar S, Shearwin-Whyatt L, Bruning JB, Shearwin KE. Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68. Acta Crystallographica. Section D, Structural Biology. 75: 670-681. PMID 31282476 DOI: 10.2210/Pdb6Pbb/Pdb  0.01
2019 Satiaputra J, Sternicki LM, Hayes AJ, Pukala TL, Booker GW, Shearwin KE, Polyak SW. Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureus. Scientific Reports. 9: 2767. PMID 30808984 DOI: 10.1038/S41598-019-39398-6  0.01
2018 Satiaputra J, Eijkelkamp BA, McDevitt CA, Shearwin KE, Booker GW, Polyak SW. Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin. Applied Microbiology and Biotechnology. PMID 29508030 DOI: 10.1007/S00253-018-8866-Z  0.01
2015 Kumar S, Priest DG, Yan Y, Dodd IB, Shearwin KE, Dunlap DD. Estimation of DNA Loop Interactions Supports the Loop Domain Model of Insulator Action Biophysical Journal. 108: 164a. DOI: 10.1016/J.Bpj.2014.11.904  0.01
2014 Shearwin K, Cui L, Murchland I, Dodd IB. Long-Range DNA Looping in the Lambda Genetic Switch Biophysical Journal. 106: 626a. DOI: 10.1016/J.Bpj.2013.11.3464  0.01
2013 Kumar S, Priest D, Biton Y, Swigon D, Shearwin K, Dodd I, Dunlap D. In Silico, In Vitro, and In Vivo Estimation of J-Factors for LAC Repressor-Mediated DNA Loop Formation Biophysical Journal. 104: 174a-175a. DOI: 10.1016/J.Bpj.2012.11.983  0.01
2011 Wang H, Dodd I, Shearwin K, Dunlap D, Finzi L. The 186 Bacteriophage Repressor as a Model System to Study Nucleosome Repositioning by Single Molecule Microscopy Biophysical Journal. 100: 230a. DOI: 10.1016/J.Bpj.2010.12.1471  0.01
2010 Wang H, Dodd IB, Shearwin K, Dunlap D, Finzi L. Coliphage 186 Genetic Switch: A Single Molecule Study Biophysical Journal. 98: 71a. DOI: 10.1016/J.Bpj.2009.12.403  0.01
2006 A Schubert R, E Shearwin K. How bacterial genes get turned on Microbiology Australia. 27: 110. DOI: 10.1071/Ma06109  0.01
2016 Satiaputra J, Shearwin KE, Booker GW, Polyak SW. Mechanisms of biotin-regulated gene expression in microbes. Synthetic and Systems Biotechnology. 1: 17-24. PMID 29062923 DOI: 10.1016/J.Synbio.2016.01.005  0
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