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Gregory A. Applegate, Ph.D. - Publications

Affiliations: 
2016 The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Organic Chemistry, Chemical Biology, Mechanistic Enzymology
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Dasgupta M, Budday D, de Oliveira SHP, Madzelan P, Marchany-Rivera D, Seravalli J, Hayes B, Sierra RG, Boutet S, Hunter MS, Alonso-Mori R, Batyuk A, Wierman J, Lyubimov A, Brewster AS, ... ... Applegate GA, et al. Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31801874 DOI: 10.1073/pnas.1901864116  0.622
2017 Malik G, Swyka RA, Tiwari VK, Fei X, Applegate GA, Berkowitz DB. A thiocyanopalladation/carbocyclization transformation identified through enzymatic screening: stereocontrolled tandem C-SCN and C-C bond formation. Chemical Science. 8: 8050-8060. PMID 29568453 DOI: 10.1039/C7Sc04083K  0.571
2017 Nelson DL, Applegate GA, Beio ML, Graham DL, Berkowitz DB. Human Serine Racemase Structure/Activity Relationship Studies Provide Mechanistic Insight and Point to Position-84 as a Hotspot for β-Elimination Function. The Journal of Biological Chemistry. PMID 28696262 DOI: 10.1074/Jbc.M117.777904  0.52
2015 Applegate GA, Berkowitz DB. Exploiting Enzymatic Dynamic Reductive Kinetic Resolution (DYRKR) in Stereocontrolled Synthesis. Advanced Synthesis & Catalysis. 357: 1619-1632. PMID 26622223 DOI: 10.1002/Adsc.201500316  0.593
2015 Panigrahi K, Applegate GA, Malik G, Berkowitz DB. Combining a Clostridial enzyme exhibiting unusual active site plasticity with a remarkably facile sigmatropic rearrangement: rapid, stereocontrolled entry into densely functionalized fluorinated phosphonates for chemical biology. Journal of the American Chemical Society. 137: 3600-9. PMID 25719907 DOI: 10.1021/Jacs.5B00022  0.72
2011 Applegate GA, Cheloha RW, Nelson DL, Berkowitz DB. A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotère side chain. Chemical Communications (Cambridge, England). 47: 2420-2. PMID 21173953 DOI: 10.1039/C0Cc04585C  0.635
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