Timothy Riley - Publications

Affiliations: 
2017 Biochemistry University of Notre Dame, Notre Dame, IN, United States 

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Partin AC, Bruno R, Shafaattalab S, Vander Mause E, Winters A, Daris M, Gahrs C, Jette CA, DiAndreth B, Sandberg ML, Hamburger AE, Kamb A, Riley TP. Geometric parameters that affect the behavior of logic-gated CAR T cells. Frontiers in Immunology. 15: 1304765. PMID 38343543 DOI: 10.3389/fimmu.2024.1304765  0.381
2022 Mock JY, Winters A, Riley TP, Bruno R, Naradikian MS, Sharma S, Jette CA, Elshimali R, Gahrs C, Toledo-Warshaviak D, West AP, Kamb A, Hamburger AE. HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen. Molecular Therapy Oncolytics. 27: 157-166. PMID 36381658 DOI: 10.1016/j.omto.2022.09.010  0.369
2019 Riley TP, Keller GLJ, Smith AR, Davancaze LM, Arbuiso AG, Devlin JR, Baker BM. Structure Based Prediction of Neoantigen Immunogenicity. Frontiers in Immunology. 10: 2047. PMID 31555277 DOI: 10.3389/Fimmu.2019.02047  0.674
2018 Hellman LM, Foley KC, Singh NK, Alonso JA, Riley TP, Devlin JR, Ayres CM, Keller GLJ, Zhang Y, Vander Kooi CW, Nishimura MI, Baker BM. Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30617019 DOI: 10.1016/J.Ymthe.2018.12.010  0.761
2018 Riley TP, Baker BM. The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics. Seminars in Cell & Developmental Biology. 84: 30-41. PMID 30449534 DOI: 10.1016/J.Semcdb.2017.10.017  0.638
2018 Riley TP, Hellman LM, Gee MH, Mendoza JL, Alonso JA, Foley KC, Nishimura MI, Vander Kooi CW, Garcia KC, Baker BM. T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability. Nature Chemical Biology. 14: 934-942. PMID 30224695 DOI: 10.1038/S41589-018-0130-4  0.788
2018 Eby JM, Smith AR, Riley TP, Cosgrove C, Ankney CM, Henning SW, Paulos CM, Garrett-Mayer E, Luiten RM, Nishimura MI, Baker BM, Le Poole IC. Molecular properties of gp100-reactive T cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells. Pigment Cell & Melanoma Research. PMID 30009548 DOI: 10.1111/Pcmr.12724  0.631
2017 Singh NK, Riley TP, Baker SCB, Borrman T, Weng Z, Baker BM. Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes. Journal of Immunology (Baltimore, Md. : 1950). 199: 2203-2213. PMID 28923982 DOI: 10.4049/Jimmunol.1700744  0.761
2017 Ayres CM, Riley TP, Corcelli SA, Baker BM. Modeling Sequence Dependent Peptide Fluctuations in Immunologic Recognition. Journal of Chemical Information and Modeling. PMID 28696685 DOI: 10.1021/Acs.Jcim.7B00118  0.597
2017 Riley TP, Mendoza J, Garcia KC, Baker BM. 2064 Journal of Clinical and Translational Science. 1: 54-55. DOI: 10.1017/cts.2017.195  0.684
2016 Harris DT, Wang N, Riley TP, Anderson SD, Singh NK, Procko E, Baker BM, Kranz DM. Deep mutational scans as a guide to engineering high-affinity T cell receptor interactions with peptide-bound MHC. The Journal of Biological Chemistry. PMID 27681597 DOI: 10.1074/Jbc.M116.748681  0.742
2016 Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, Baker BM. A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. Protein Engineering, Design & Selection : Peds. PMID 27624308 DOI: 10.1093/Protein/Gzw050  0.754
2016 Riley TP, Singh NK, Pierce BG, Weng Z, Baker BM. Computational Modeling of T Cell Receptor Complexes. Methods in Molecular Biology (Clifton, N.J.). 1414: 319-40. PMID 27094300 DOI: 10.1007/978-1-4939-3569-7_19  0.757
2016 Riley TP, Singh NK, Pierce BG, Baker BM, Weng Z. Computational Reprogramming of T Cell Antigen Receptor Binding Properties. Methods in Molecular Biology (Clifton, N.J.). 1414: 305-18. PMID 27094299 DOI: 10.1007/978-1-4939-3569-7_18  0.787
2016 Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, et al. Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability. Journal of Leukocyte Biology. PMID 26921345 DOI: 10.1189/Jlb.2A1215-561R  0.735
2016 Hellman LM, Yin L, Wang Y, Blevins SJ, Riley TP, Belden OS, Spear TT, Nishimura MI, Stern LJ, Baker BM. Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes. Journal of Immunological Methods. PMID 26906089 DOI: 10.1016/J.Jim.2016.02.016  0.718
2016 Blevins SJ, Pierce BG, Singh NK, Riley TP, Wang Y, Spear TT, Nishimura MI, Weng Z, Baker BM. How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884163 DOI: 10.1073/Pnas.1522069113  0.721
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