Year |
Citation |
Score |
2022 |
Chauhan U, Barth VC, Woychik NA. tRNA Inactivating Mycobacterium tuberculosis VapBC Toxin-Antitoxin Systems as Therapeutic Targets. Antimicrobial Agents and Chemotherapy. e0189621. PMID 35404073 DOI: 10.1128/aac.01896-21 |
0.387 |
|
2019 |
Barth VC, Woychik NA. The Sole MazF Toxin Targets tRNA to Impart Highly Selective, Codon-Dependent Proteome Reprogramming. Frontiers in Genetics. 10: 1356. PMID 32117414 DOI: 10.3389/Fgene.2019.01356 |
0.433 |
|
2019 |
Barth VC, Zeng JM, Vvedenskaya IO, Ouyang M, Husson RN, Woychik NA. Toxin-mediated ribosome stalling reprograms the Mycobacterium tuberculosis proteome. Nature Communications. 10: 3035. PMID 31292443 DOI: 10.1038/S41467-019-10869-8 |
0.382 |
|
2019 |
Cintrón M, Zeng JM, Barth VC, Cruz JW, Husson RN, Woychik NA. Accurate target identification for Mycobacterium tuberculosis endoribonuclease toxins requires expression in their native host. Scientific Reports. 9: 5949. PMID 30976025 DOI: 10.1038/S41598-019-41548-9 |
0.454 |
|
2017 |
Schifano JM, Woychik NA. Cloaked dagger: tRNA slicing by an unlikely culprit. Rna Biology. 14: 15-19. PMID 27841735 DOI: 10.1080/15476286.2016.1255396 |
0.36 |
|
2016 |
Schifano JM, Cruz JW, Vvedenskaya IO, Edifor R, Ouyang M, Husson RN, Nickels BE, Woychik NA. tRNA is a new target for cleavage by a MazF toxin. Nucleic Acids Research. 44: 1256-70. PMID 26740583 DOI: 10.1093/Nar/Gkv1370 |
0.49 |
|
2016 |
Cruz JW, Woychik NA. tRNAs taking charge. Pathogens and Disease. 74. PMID 26657107 DOI: 10.1093/Femspd/Ftv117 |
0.495 |
|
2015 |
Cruz JW, Sharp JD, Hoffer ED, Maehigashi T, Vvedenskaya IO, Konkimalla A, Husson RN, Nickels BE, Dunham CM, Woychik NA. Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase. Nature Communications. 6: 7480. PMID 26158745 DOI: 10.1038/Ncomms8480 |
0.414 |
|
2014 |
Cruz JW, Woychik NA. Teaching Fido new ModiFICation tricks. Plos Pathogens. 10: e1004349. PMID 25255332 DOI: 10.1371/Journal.Ppat.1004349 |
0.367 |
|
2014 |
Schifano JM, Vvedenskaya IO, Knoblauch JG, Ouyang M, Nickels BE, Woychik NA. An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. Nature Communications. 5: 3538. PMID 24709835 DOI: 10.1038/Ncomms4538 |
0.491 |
|
2014 |
Schifano JM, Woychik NA. 23S rRNA as an a-Maz-ing new bacterial toxin target. Rna Biology. 11: 101-5. PMID 24525465 DOI: 10.4161/Rna.27949 |
0.35 |
|
2014 |
Cruz JW, Rothenbacher FP, Maehigashi T, Lane WS, Dunham CM, Woychik NA. Doc toxin is a kinase that inactivates elongation factor Tu. The Journal of Biological Chemistry. 289: 7788-98. PMID 24448800 DOI: 10.1074/Jbc.M113.544429 |
0.412 |
|
2013 |
Schifano JM, Edifor R, Sharp JD, Ouyang M, Konkimalla A, Husson RN, Woychik NA. Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site. Proceedings of the National Academy of Sciences of the United States of America. 110: 8501-6. PMID 23650345 DOI: 10.1073/Pnas.1222031110 |
0.481 |
|
2012 |
Rothenbacher FP, Suzuki M, Hurley JM, Montville TJ, Kirn TJ, Ouyang M, Woychik NA. Clostridium difficile MazF toxin exhibits selective, not global, mRNA cleavage. Journal of Bacteriology. 194: 3464-74. PMID 22544268 DOI: 10.1128/Jb.00217-12 |
0.672 |
|
2012 |
Sharp JD, Cruz JW, Raman S, Inouye M, Husson RN, Woychik NA. Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin. The Journal of Biological Chemistry. 287: 12835-47. PMID 22354968 DOI: 10.1074/Jbc.M112.340109 |
0.608 |
|
2011 |
Hurley JM, Cruz JW, Ouyang M, Woychik NA. Bacterial toxin RelE mediates frequent codon-independent mRNA cleavage from the 5' end of coding regions in vivo. The Journal of Biological Chemistry. 286: 14770-8. PMID 21324908 DOI: 10.1074/Jbc.M110.108969 |
0.688 |
|
2010 |
Zhu L, Sharp JD, Kobayashi H, Woychik NA, Inouye M. Noncognate Mycobacterium tuberculosis toxin-antitoxins can physically and functionally interact. The Journal of Biological Chemistry. 285: 39732-8. PMID 20876537 DOI: 10.1074/Jbc.M110.163105 |
0.533 |
|
2010 |
Arbing MA, Handelman SK, Kuzin AP, Verdon G, Wang C, Su M, Rothenbacher FP, Abashidze M, Liu M, Hurley JM, Xiao R, Acton T, Inouye M, Montelione GT, Woychik NA, et al. Crystal structures of Phd-Doc, HigA, and YeeU establish multiple evolutionary links between microbial growth-regulating toxin-antitoxin systems. Structure (London, England : 1993). 18: 996-1010. PMID 20696400 DOI: 10.1016/J.Str.2010.04.018 |
0.684 |
|
2010 |
Verdon G, DeStefano L, Wang C, Boel G, Montelione G, Woychik N, Hunt JF. Structural and Functional Studies of Bacterial Toxin-Antitoxin Systems Biophysical Journal. 98: 246a-247a. DOI: 10.1016/J.Bpj.2009.12.1341 |
0.358 |
|
2009 |
Hurley JM, Woychik NA. Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites. The Journal of Biological Chemistry. 284: 18605-13. PMID 19423702 DOI: 10.1074/Jbc.M109.008763 |
0.688 |
|
2009 |
Prysak MH, Mozdzierz CJ, Cook AM, Zhu L, Zhang Y, Inouye M, Woychik NA. Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage. Molecular Microbiology. 71: 1071-87. PMID 19210620 DOI: 10.1111/J.1365-2958.2008.06572.X |
0.605 |
|
2008 |
Liu M, Zhang Y, Inouye M, Woychik NA. Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 105: 5885-90. PMID 18398006 DOI: 10.1073/Pnas.0711949105 |
0.578 |
|
2006 |
Suzuki M, Roy R, Zheng H, Woychik N, Inouye M. Bacterial bioreactors for high yield production of recombinant protein. The Journal of Biological Chemistry. 281: 37559-65. PMID 17020876 DOI: 10.1074/Jbc.M608806200 |
0.497 |
|
2005 |
Suzuki M, Zhang J, Liu M, Woychik NA, Inouye M. Single protein production in living cells facilitated by an mRNA interferase. Molecular Cell. 18: 253-61. PMID 15837428 DOI: 10.1016/J.Molcel.2005.03.011 |
0.55 |
|
2003 |
Tan Q, Prysak MH, Woychik NA. Loss of the Rpb4/Rpb7 subcomplex in a mutant form of the Rpb6 subunit shared by RNA polymerases I, II, and III. Molecular and Cellular Biology. 23: 3329-38. PMID 12697831 DOI: 10.1128/Mcb.23.9.3329-3338.2003 |
0.469 |
|
2002 |
Woychik NA, Hampsey M. The RNA polymerase II machinery: structure illuminates function. Cell. 108: 453-63. PMID 11909517 DOI: 10.1016/S0092-8674(02)00646-3 |
0.432 |
|
2001 |
Miyao T, Barnett JD, Woychik NA. Deletion of the RNA polymerase subunit RPB4 acts as a global, not stress-specific, shut-off switch for RNA polymerase II transcription at high temperatures. The Journal of Biological Chemistry. 276: 46408-13. PMID 11577101 DOI: 10.1074/Jbc.M107012200 |
0.464 |
|
2000 |
Tan Q, Li X, Sadhale PP, Miyao T, Woychik NA. Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant. Molecular and Cellular Biology. 20: 8124-33. PMID 11027282 DOI: 10.1128/Mcb.20.21.8124-8133.2000 |
0.456 |
|
2000 |
Tan Q, Linask KL, Ebright RH, Woychik NA. Activation mutants in yeast RNA polymerase II subunit RPB3 provide evidence for a structurally conserved surface required for activation in eukaryotes and bacteria Genes and Development. 14: 339-348. PMID 10673505 DOI: 10.1101/Gad.14.3.339 |
0.467 |
|
2000 |
Woychik N. TA-TAAA!! Transcription unveiled Trends in Biochemical Sciences. 25: 404. DOI: 10.1016/S0968-0004(00)01622-4 |
0.402 |
|
1999 |
Miyao T, Woychik NA. RNA polymerase subunit RPB5 plays a role in transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 95: 15281-6. PMID 9860960 DOI: 10.1073/Pnas.95.26.15281 |
0.447 |
|
1995 |
McKune K, Moore PA, Hull MW, Woychik NA. Six human RNA polymerase subunits functionally substitute for their yeast counterparts Molecular and Cellular Biology. 15: 6895-6900. PMID 8524256 DOI: 10.1128/Mcb.15.12.6895 |
0.437 |
|
1995 |
Hull MW, McKune K, Woychik NA. RNA polymerase II subunit RPB9 is required for accurate start site selection Genes and Development. 9: 481-490. PMID 7883169 DOI: 10.1101/GAD.9.4.481 |
0.372 |
|
1995 |
Khazak V, Sadhale PP, Woychik NA, Brent R, Golemis EA. Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Molecular Biology of the Cell. 6: 759-75. PMID 7579693 DOI: 10.1091/Mbc.6.7.759 |
0.464 |
|
1994 |
McKune K, Woychik NA. Functional substitution of an essential yeast RNA polymerase subunit by a highly conserved mammalian counterpart. Molecular and Cellular Biology. 14: 4155-9. PMID 8196653 DOI: 10.1128/Mcb.14.6.4155 |
0.461 |
|
1994 |
Sadhale PP, Woychik NA. C25, an essential RNA polymerase III subunit related to the RNA polymerase II subunit RPB7. Molecular and Cellular Biology. 14: 6164-70. PMID 8065349 DOI: 10.1128/Mcb.14.9.6164 |
0.474 |
|
1994 |
McKune K, Woychik NA. Halobacterial S9 operon contains two genes encoding proteins homologous to subunits shared by eukaryotic RNA polymerases I, II, and III. Journal of Bacteriology. 176: 4754-6. PMID 8045907 DOI: 10.1128/Jb.176.15.4754-4756.1994 |
0.472 |
|
1993 |
Woychik NA, Young RA. RNA polymerase II subunit RPB10 is essential for yeast cell viability. The Journal of Biological Chemistry. 268: 12230. PMID 8505344 |
0.496 |
|
1993 |
McKune K, Richards KL, Edwards AM, Young RA, Woychik NA. RPB7, one of two dissociable subunits of yeast RNA polymerase II, is essential for cell viability. Yeast (Chichester, England). 9: 295-9. PMID 8488730 DOI: 10.1002/Yea.320090309 |
0.586 |
|
1993 |
Woychik N, Young R. RNA polymerase II subunit RPB10 is essential for yeast cell viability Journal of Biological Chemistry. 268: 12230. DOI: 10.1016/s0021-9258(19)50331-3 |
0.326 |
|
1992 |
Woychik NA, Young RA. Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 89: 3999-4003. PMID 1570325 DOI: 10.1073/Pnas.89.9.3999 |
0.56 |
|
1991 |
Woychik N, Lane W, Young R. Yeast RNA polymerase II subunit RPB9 is essential for growth at temperature extremes. Journal of Biological Chemistry. 266: 19053-19055. DOI: 10.1016/s0021-9258(18)55171-1 |
0.479 |
|
1990 |
Woychik NA, Liao SM, Kolodziej PA, Young RA. Subunits shared by eukaryotic nuclear RNA polymerases. Genes & Development. 4: 313-23. PMID 2186966 DOI: 10.1101/Gad.4.3.313 |
0.605 |
|
1990 |
Kolodziej PA, Woychik N, Liao SM, Young RA. RNA polymerase II subunit composition, stoichiometry, and phosphorylation. Molecular and Cellular Biology. 10: 1915-20. PMID 2183013 DOI: 10.1128/Mcb.10.5.1915 |
0.568 |
|
1990 |
Woychik NA, Young RA. RNA polymerase II: subunit structure and function. Trends in Biochemical Sciences. 15: 347-51. PMID 1700503 DOI: 10.1016/0968-0004(90)90074-L |
0.569 |
|
1989 |
Woychik NA, Young RA. RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Molecular and Cellular Biology. 9: 2854-9. PMID 2674672 DOI: 10.1128/Mcb.9.7.2854 |
0.595 |
|
1988 |
Richardson JM, Woychik NA, Ebert DL, Dimond RL, Cardelli JA. Inhibition of early but not late proteolytic processing events leads to the missorting and oversecretion of precursor forms of lysosomal enzymes in Dictyostelium discoideum. The Journal of Cell Biology. 107: 2097-107. PMID 3143734 DOI: 10.1083/Jcb.107.6.2097 |
0.618 |
|
1987 |
Cardelli JA, Golumbeski GS, Woychik NA, Ebert DL, Mierendorf RC, Dimond RL. Defining the intracellular localization pathways followed by lysosomal enzymes in Dictyostelium discoideum. Methods in Cell Biology. 28: 139-55. PMID 3600404 DOI: 10.1016/S0091-679X(08)61641-6 |
0.605 |
|
1987 |
Livi GP, Woychik NA, Dimond RL. A late developmental change in lysosomal enzyme sulfation specific to newly synthesized proteins in Dictyostelium discoideum. Developmental Biology. 121: 293-300. PMID 3108046 DOI: 10.1016/0012-1606(87)90164-3 |
0.615 |
|
1985 |
Livi GP, Woychik NA, Dimond RL. Lysosomal enzyme inactivation associated with defects in post-translational modification during development in Dictyostelium discoideum. Differentiation; Research in Biological Diversity. 30: 83-91. PMID 3913611 DOI: 10.1111/J.1432-0436.1985.Tb00518.X |
0.615 |
|
Low-probability matches (unlikely to be authored by this person) |
2021 |
Barth VC, Chauhan U, Zeng J, Su X, Zheng H, Husson RN, Woychik NA. VapC4 toxin engages small ORFs to initiate an integrated oxidative and copper stress response. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34362841 DOI: 10.1073/pnas.2022136118 |
0.297 |
|
2023 |
Troian EA, Maldonado HM, Chauhan U, Barth VC, Woychik NA. Mycobacterium abscessus VapC5 toxin potentiates evasion of antibiotic killing by ribosome overproduction and activation of multiple resistance pathways. Nature Communications. 14: 3705. PMID 37349306 DOI: 10.1038/s41467-023-38844-4 |
0.29 |
|
1999 |
Woychik NA. Fractions to functions: RNA polymerase II thirty years later. Cold Spring Harbor Symposia On Quantitative Biology. 63: 311-7. PMID 10384295 DOI: 10.1101/SQB.1998.63.311 |
0.254 |
|
1994 |
Woychik NA. Regulating the regulators. Trends in Biochemical Sciences. 19: 103-5. PMID 8203014 DOI: 10.1016/0968-0004(94)90199-6 |
0.244 |
|
2014 |
Cruz JW, Rothenbacher FP, Maehigashi T, Lane WS, Dunham CM, Woychik NA. Doc toxin is a kinase that inactivates elongation factor Tu (Journal of Biological Chemistry (2014) 289 (7788-7798)) Journal of Biological Chemistry. 289: 19276. DOI: 10.1074/Jbc.A113.544429 |
0.238 |
|
1986 |
Woychik NA, Cardelli JA, Dimond RL. A conformationally altered precursor to the lysosomal enzyme alpha-mannosidase accumulates in the endoplasmic reticulum in a mutant strain of Dictyostelium discoideum. Journal of Biological Chemistry. 261: 9595-9602. DOI: 10.1016/s0021-9258(18)67555-6 |
0.195 |
|
1984 |
Woychik NA, Hinsdill RD, Chu FS. Production and characterization of monoclonal antibodies against aflatoxin M1. Applied and Environmental Microbiology. 48: 1096-9. PMID 6440484 |
0.163 |
|
1987 |
Woychik N, Dimond R. A single mutation prevents the normal intracellular transport of multiple lysosomal proteins from the rough endoplasmic reticulum. Journal of Biological Chemistry. 262: 10008-10014. DOI: 10.1016/s0021-9258(18)61066-x |
0.118 |
|
1982 |
Taylor SL, Woychik NA. Simple Medium for Assessing Quantitative Production of Histamine by Enterobacteriaceae. Journal of Food Protection. 45: 747-751. PMID 30866206 DOI: 10.4315/0362-028X-45.8.747 |
0.1 |
|
2019 |
Hu WJ, Woychik N, Chu FS. ELISA of Picogram Quantities of Aflatoxin M in Urine and Milk. Journal of Food Protection. 47: 126-127. PMID 30921911 DOI: 10.4315/0362-028X-47.2.126 |
0.056 |
|
Hide low-probability matches. |