James Dewar - Publications

Affiliations: 
2011-2016 Vanderbilt University Medical Center, Nashville, TN, United States 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Van Ravenstein SX, Dewar JM. Use of Xenopus Egg Extracts to Study the Effects of Topoisomerase Poisons During Vertebrate DNA Replication. Methods in Molecular Biology (Clifton, N.J.). 2928: 151-172. PMID 40372644 DOI: 10.1007/978-1-0716-4550-5_13  0.715
2025 Cranford MT, Dahmen SN, Cortez D, Dewar JM. Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms. Biorxiv : the Preprint Server For Biology. PMID 39829849 DOI: 10.1101/2025.01.09.632187  0.611
2024 Dewar JM. DNA replication recruits a friend to overcome a challenging break-up. The Embo Journal. PMID 39169154 DOI: 10.1038/s44318-024-00204-3  0.721
2024 Vontalge EJ, Kavlashvili T, Dahmen SN, Cranford MT, Dewar JM. Control of DNA replication in vitro using a reversible replication barrier. Nature Protocols. PMID 38594502 DOI: 10.1038/s41596-024-00977-1  0.686
2023 Campos LV, Van Ravenstein SX, Vontalge EJ, Greer BH, Heintzman DR, Kavlashvili T, McDonald WH, Rose KL, Eichman BF, Dewar JM. RTEL1 and MCM10 overcome topological stress during vertebrate replication termination. Cell Reports. 42: 112109. PMID 36807139 DOI: 10.1016/j.celrep.2023.112109  0.503
2023 Kavlashvili T, Liu W, Mohamed TM, Cortez D, Dewar JM. Replication fork uncoupling causes nascent strand degradation and fork reversal. Nature Structural & Molecular Biology. PMID 36593312 DOI: 10.1038/s41594-022-00871-y  0.583
2022 Conwell SC, Cranford MT, Kavlashvili T, Dewar JM. Replication fork collapse in vitro using Xenopus egg extracts. Methods in Enzymology. 672: 317-338. PMID 35934482 DOI: 10.1016/bs.mie.2022.03.017  0.674
2022 Van Ravenstein SX, Mehta KP, Kavlashvili T, Byl JAW, Zhao R, Osheroff N, Cortez D, Dewar JM. Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms. The Embo Journal. e110632. PMID 35578785 DOI: 10.15252/embj.2022110632  0.717
2022 Kavlashvili T, Dewar JM. Correction to: Approaches to Monitor Termination of DNA Replication Using Xenopus Egg Extracts. Methods in Molecular Biology (Clifton, N.J.). 2444: C1. PMID 35538349 DOI: 10.1007/978-1-0716-2063-2_17  0.599
2022 Kavlashvili T, Dewar JM. Approaches to Monitor Termination of DNA Replication Using Xenopus Egg Extracts. Methods in Molecular Biology (Clifton, N.J.). 2444: 105-123. PMID 35290634 DOI: 10.1007/978-1-0716-2063-2_7  0.686
2021 Vrtis KB, Dewar JM, Chistol G, Wu RA, Graham TGW, Walter JC. Single-strand DNA breaks cause replisome disassembly. Molecular Cell. PMID 33484638 DOI: 10.1016/j.molcel.2020.12.039  0.781
2019 Heintzman DR, Campos LV, Byl JAW, Osheroff N, Dewar JM. Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination. Cell Reports. 29: 422-436.e5. PMID 31597101 DOI: 10.1016/J.Celrep.2019.08.097  0.543
2017 Parisis N, Krasinska L, Harker B, Urbach S, Rossignol M, Camasses A, Dewar J, Morin N, Fisher D. Initiation of DNA replication requires actin dynamics and formin activity. The Embo Journal. PMID 28982779 DOI: 10.15252/Embj.201796585  0.588
2017 Dewar JM, Walter JC. Mechanisms of DNA replication termination. Nature Reviews. Molecular Cell Biology. PMID 28537574 DOI: 10.1038/Nrm.2017.42  0.709
2017 Dewar JM, Low E, Mann M, Räschle M, Walter JC. CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination. Genes & Development. PMID 28235849 DOI: 10.1101/Gad.291799.116  0.681
2015 Dewar JM, Budzowska M, Walter JC. The mechanism of DNA replication termination in vertebrates. Nature. 525: 345-50. PMID 26322582 DOI: 10.1038/Nature14887  0.775
2015 Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC. DNA interstrand cross-link repair requires replication-fork convergence. Nature Structural & Molecular Biology. 22: 242-7. PMID 25643322 DOI: 10.1038/Nsmb.2956  0.784
2014 Duxin JP, Dewar JM, Yardimci H, Walter JC. Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 159: 346-57. PMID 25303529 DOI: 10.1016/J.Cell.2014.09.024  0.548
2014 Castillo Bosch P, Segura-Bayona S, Koole W, van Heteren JT, Dewar JM, Tijsterman M, Knipscheer P. FANCJ promotes DNA synthesis through G-quadruplex structures. The Embo Journal. 33: 2521-33. PMID 25193968 DOI: 10.15252/Embj.201488663  0.648
2013 Dewar JM, Walter JC. Chromosome biology: conflict management for replication and transcription. Current Biology : Cb. 23: R200-2. PMID 23473562 DOI: 10.1016/J.Cub.2013.01.054  0.635
2012 Dewar JM, Lydall D. Simple, non-radioactive measurement of single-stranded DNA at telomeric, sub-telomeric, and genomic loci in budding yeast. Methods in Molecular Biology (Clifton, N.J.). 920: 341-8. PMID 22941615 DOI: 10.1007/978-1-61779-998-3_24  0.589
2012 Dewar JM, Lydall D. Similarities and differences between "uncapped" telomeres and DNA double-strand breaks. Chromosoma. 121: 117-30. PMID 22203190 DOI: 10.1007/s00412-011-0357-2  0.692
2010 Dewar JM, Lydall D. Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. The Embo Journal. 29: 4020-34. PMID 21045806 DOI: 10.1038/emboj.2010.267  0.5
2008 Addinall SG, Downey M, Yu M, Zubko MK, Dewar J, Leake A, Hallinan J, Shaw O, James K, Wilkinson DJ, Wipat A, Durocher D, Lydall D. A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics. 180: 2251-66. PMID 18845848 DOI: 10.1534/Genetics.108.092577  0.5
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