Christine Ann Collins - Publications

Affiliations: 
1988-1997 Northwestern University, Evanston, IL 
 1997-2018 AbbVie 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Poordad F, Hezode C, Trinh R, Kowdley KV, Zeuzem S, Agarwal K, Shiffman ML, Wedemeyer H, Berg T, Yoshida EM, Forns X, Lovell SS, Da Silva-Tillmann B, Collins CA, Campbell AL, et al. ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis. The New England Journal of Medicine. 370: 1973-82. PMID 24725237 DOI: 10.1056/NEJMoa1402869  1
2014 DeGoey DA, Randolph JT, Liu D, Pratt J, Hutchins C, Donner P, Krueger AC, Matulenko M, Patel S, Motter CE, Nelson L, Keddy R, Tufano M, Caspi DD, Krishnan P, ... ... Collins C, et al. Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5A. Journal of Medicinal Chemistry. 57: 2047-57. PMID 24400777 DOI: 10.1021/Jm401398X  1
2012 Yeh VS, Beno DW, Brodjian S, Brune ME, Cullen SC, Dayton BD, Dhaon MK, Falls HD, Gao J, Grihalde N, Hajduk P, Hansen TM, Judd AS, King AJ, Klix RC, ... ... Collins CA, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1. Journal of Medicinal Chemistry. 55: 1751-7. PMID 22263872 DOI: 10.1021/Jm201524G  1
2010 King AJ, Segreti JA, Larson KJ, Souers AJ, Kym PR, Reilly RM, Collins CA, Voorbach MJ, Zhao G, Mittelstadt SW, Cox BF. In vivo efficacy of acyl CoA: diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia. European Journal of Pharmacology. 637: 155-61. PMID 20385122 DOI: 10.1016/J.Ejphar.2010.03.056  1
2008 Xin Z, Zhao H, Serby MD, Liu B, Liu M, Szczepankiewicz BG, Nelson LT, Smith HT, Suhar TS, Janis RS, Cao N, Camp HS, Collins CA, Sham HL, Surowy TK, et al. Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 4298-302. PMID 18632269 DOI: 10.1016/J.Bmcl.2008.06.088  1
2008 Zhao G, Souers AJ, Voorbach M, Falls HD, Droz B, Brodjian S, Lau YY, Iyengar RR, Gao J, Judd AS, Wagaw SH, Ravn MM, Engstrom KM, Lynch JK, Mulhern MM, ... ... Collins CA, et al. Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. Journal of Medicinal Chemistry. 51: 380-3. PMID 18183944 DOI: 10.1021/Jm7013887  1
2007 Yang R, Wilcox DM, Haasch DL, Jung PM, Nguyen PT, Voorbach MJ, Doktor S, Brodjian S, Bush EN, Lin E, Jacobson PB, Collins CA, Landschulz KT, Trevillyan JM, Rondinone CM, et al. Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice. The Journal of Biological Chemistry. 282: 22765-74. PMID 17550900 DOI: 10.1074/Jbc.M700790200  1
2007 Liu G, Lynch JK, Freeman J, Liu B, Xin Z, Zhao H, Serby MD, Kym PR, Suhar TS, Smith HT, Cao N, Yang R, Janis RS, Krauser JA, Cepa SP, ... ... Collins CA, et al. Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors. Journal of Medicinal Chemistry. 50: 3086-100. PMID 17530838 DOI: 10.1021/Jm070219P  1
2007 Xu H, Wilcox D, Nguyen P, Voorbach M, Smith H, Brodjian S, Suhar T, Reilly RM, Jacobson PB, Collins CA, Landschulz K, Surowy TK. Hepatic knockdown of stearoyl-CoA desaturase 1 via RNA interference in obese mice decreases lipid content and changes fatty acid composition. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3781-94. PMID 17485339 DOI: 10.2741/2352  1
2007 Zhao H, Serby MD, Smith HT, Cao N, Suhar TS, Surowy TK, Camp HS, Collins CA, Sham HL, Liu G. Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 3388-91. PMID 17434733 DOI: 10.1016/J.Bmcl.2007.03.099  1
2007 Judd AS, Souers AJ, Wodka D, Zhao G, Mulhern MM, Iyengar RR, Gao J, Lynch JK, Freeman JC, Falls HD, Brodjian S, Dayton BD, Reilly RM, Gintant G, Limberis JT, ... ... Collins CA, et al. Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity. Bioorganic & Medicinal Chemistry Letters. 17: 2365-71. PMID 17350253 DOI: 10.1016/J.Bmcl.2006.11.068  1
2007 Iyengar RR, Lynch JK, Mulhern MM, Judd AS, Freeman JC, Gao J, Souers AJ, Zhao G, Wodka D, Doug Falls H, Brodjian S, Dayton BD, Reilly RM, Swanson S, Su Z, ... ... Collins CA, et al. An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 874-8. PMID 17234405 DOI: 10.1016/J.Bmcl.2006.11.065  1
2007 Souers AJ, Iyengar RR, Judd AS, Beno DW, Gao J, Zhao G, Brune ME, Napier JJ, Mulhern MM, Lynch JK, Freeman JC, Wodka D, Chen CJ, Falls HD, Brodjian S, ... ... Collins CA, et al. Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines. Bioorganic & Medicinal Chemistry Letters. 17: 884-9. PMID 17188866 DOI: 10.1016/J.Bmcl.2006.11.061  1
2006 Wilcox DM, Yang R, Morgan SJ, Nguyen PT, Voorbach MJ, Jung PM, Haasch DL, Lin E, Bush EN, Opgenorth TJ, Jacobson PB, Collins CA, Rondinone CM, Surowy T, Landschulz KT. Delivery of RNAi reagents in murine models of obesity and diabetes. Journal of Rnai and Gene Silencing : An International Journal of Rna and Gene Targeting Research. 3: 225-36. PMID 19771218  1
2006 Lynch JK, Freeman JC, Judd AS, Iyengar R, Mulhern M, Zhao G, Napier JJ, Wodka D, Brodjian S, Dayton BD, Falls D, Ogiela C, Reilly RM, Campbell TJ, Polakowski JS, ... ... Collins CA, et al. Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety. Journal of Medicinal Chemistry. 49: 6569-84. PMID 17064075 DOI: 10.1021/jm060683e  1
2006 Xu H, Wilcox D, Nguyen P, Voorbach M, Suhar T, Morgan SJ, An WF, Ge L, Green J, Wu Z, Gimeno RE, Reilly R, Jacobson PB, Collins CA, Landschulz K, et al. Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile. Biochemical and Biophysical Research Communications. 349: 439-48. PMID 16935266 DOI: 10.1016/J.Bbrc.2006.08.071  1
2006 Falls HD, Dayton BD, Fry DG, Ogiela CA, Schaefer VG, Brodjian S, Reilly RM, Collins CA, Kaszubska W. Characterization of ghrelin receptor activity in a rat pituitary cell line RC-4B/C. Journal of Molecular Endocrinology. 37: 51-62. PMID 16901923 DOI: 10.1677/jme.1.01943  1
2006 Xin Z, Serby MD, Zhao H, Kosogof C, Szczepankiewicz BG, Liu M, Liu B, Hutchins CW, Sarris KA, Hoff ED, Falls HD, Lin CW, Ogiela CA, Collins CA, Brune ME, et al. Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists. Journal of Medicinal Chemistry. 49: 4459-69. PMID 16854051 DOI: 10.1021/jm060461g  1
2006 Basso AM, Bratcher NA, Gallagher KB, Cowart MD, Zhao C, Sun M, Esbenshade TA, Brune ME, Fox GB, Schmidt M, Collins CA, Souers AJ, Iyengar R, Vasudevan A, Kym PR, et al. Lack of efficacy of melanin-concentrating hormone-1 receptor antagonists in models of depression and anxiety. European Journal of Pharmacology. 540: 115-20. PMID 16765941 DOI: 10.1016/J.Ejphar.2006.04.043  1
2006 Serby MD, Zhao H, Szczepankiewicz BG, Kosogof C, Xin Z, Liu B, Liu M, Nelson LT, Kaszubska W, Falls HD, Schaefer V, Bush EN, Shapiro R, Droz BA, Knourek-Segel VE, ... ... Collins CA, et al. 2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists. Journal of Medicinal Chemistry. 49: 2568-78. PMID 16610800 DOI: 10.1021/jm0510934  1
2006 Kym PR, Souers AJ, Campbell TJ, Lynch JK, Judd AS, Iyengar R, Vasudevan A, Gao J, Freeman JC, Wodka D, Mulhern M, Zhao G, Wagaw SH, Napier JJ, Brodjian S, ... ... Collins CA, et al. Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists. Journal of Medicinal Chemistry. 49: 2339-52. PMID 16570930 DOI: 10.1021/Jm0512286  1
2006 Fry D, Dayton B, Brodjian S, Ogiela C, Sidorowicz H, Frost LJ, McNally T, Reilly RM, Collins CA. Characterization of a neuronal cell line expressing native human melanin-concentrating hormone receptor 1 (MCHR1). The International Journal of Biochemistry & Cell Biology. 38: 1290-9. PMID 16524757 DOI: 10.1016/j.biocel.2006.01.007  1
2006 Blackburn C, LaMarche MJ, Brown J, Che JL, Cullis CA, Lai S, Maguire M, Marsilje T, Geddes B, Govek E, Kadambi V, Doherty C, Dayton B, Brodjian S, Marsh KC, ... Collins CA, et al. Identification and characterization of amino-piperidinequinolones and quinazolinones as MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters. 16: 2621-7. PMID 16524729 DOI: 10.1016/j.bmcl.2006.02.044  1
2006 Liu B, Liu M, Xin Z, Zhao H, Serby MD, Kosogof C, Nelson LT, Szczepankiewicz BG, Kaszubska W, Schaefer VG, Falls HD, Lin CW, Collins CA, Sham HL, Liu G. Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration. Bioorganic & Medicinal Chemistry Letters. 16: 1864-8. PMID 16442284 DOI: 10.1016/j.bmcl.2006.01.012  1
2005 Vasudevan A, Souers AJ, Freeman JC, Verzal MK, Gao J, Mulhern MM, Wodka D, Lynch JK, Engstrom KM, Wagaw SH, Brodjian S, Dayton B, Falls DH, Bush E, Brune M, ... ... Collins CA, et al. Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 5293-7. PMID 16203136 DOI: 10.1016/J.Bmcl.2005.08.049  1
2005 Kym PR, Iyengar R, Souers AJ, Lynch JK, Judd AS, Gao J, Freeman J, Mulhern M, Zhao G, Vasudevan A, Wodka D, Blackburn C, Brown J, Che JL, Cullis C, ... ... Collins CA, et al. Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists. Journal of Medicinal Chemistry. 48: 5888-91. PMID 16161992 DOI: 10.1021/Jm050598R  1
2005 Vasudevan A, LaMarche MJ, Blackburn C, Che JL, Luchaco-Cullis CA, Lai S, Marsilje TH, Patane MA, Souers AJ, Wodka D, Geddes B, Chen S, Brodjian S, Falls DH, Dayton BD, ... ... Collins CA, et al. Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 4174-9. PMID 16085414 DOI: 10.1016/J.Bmcl.2005.06.089  1
2005 Vasudevan A, Verzal MK, Wodka D, Souers AJ, Blackburn C, Che JL, Lai S, Brodjian S, Falls DH, Dayton BD, Govek E, Daniels T, Geddes B, Marsh KC, Hernandez LE, ... Collins CA, et al. Identification of aminopiperidine benzamides as MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 3412-6. PMID 15950463 DOI: 10.1016/J.Bmcl.2005.05.023  1
2005 Souers AJ, Gao J, Wodka D, Judd AS, Mulhern MM, Napier JJ, Brune ME, Bush EN, Brodjian SJ, Dayton BD, Shapiro R, Hernandez LE, Marsh KC, Sham HL, Collins CA, et al. Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity. Bioorganic & Medicinal Chemistry Letters. 15: 2752-7. PMID 15911251 DOI: 10.1016/J.Bmcl.2005.03.114  1
2005 Zhao H, Xin Z, Patel JR, Nelson LT, Liu B, Szczepankiewicz BG, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL, Liu G. Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 1825-8. PMID 15780615 DOI: 10.1016/j.bmcl.2005.02.026  1
2005 Souers AJ, Gao J, Brune M, Bush E, Wodka D, Vasudevan A, Judd AS, Mulhern M, Brodjian S, Dayton B, Shapiro R, Hernandez LE, Marsh KC, Sham HL, Collins CA, et al. Identification of 2-(4-benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an orally efficacious melanin-concentrating hormone receptor 1 antagonist for the treatment of obesity. Journal of Medicinal Chemistry. 48: 1318-21. PMID 15743174 DOI: 10.1021/Jm0490890  1
2004 Zhao H, Xin Z, Liu G, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Discovery of tetralin carboxamide growth hormone secretagogue receptor antagonists via scaffold manipulation. Journal of Medicinal Chemistry. 47: 6655-7. PMID 15615511 DOI: 10.1021/jm0491750  1
2004 Liu B, Liu G, Xin Z, Serby MD, Zhao H, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Novel isoxazole carboxamides as growth hormone secretagogue receptor (GHS-R) antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 5223-6. PMID 15380232 DOI: 10.1016/J.Bmcl.2004.06.060  1
2004 Souers AJ, Wodka D, Gao J, Lewis JC, Vasudevan A, Brodjian S, Dayton B, Ogiela CA, Fry D, Hernandez LE, Marsh KC, Collins CA, Kym PR. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 3. Bioorganic & Medicinal Chemistry Letters. 14: 4883-6. PMID 15341944 DOI: 10.1016/J.Bmcl.2004.07.035  1
2004 Vasudevan A, Wodka D, Verzal MK, Souers AJ, Gao J, Brodjian S, Fry D, Dayton B, Marsh KC, Hernandez LE, Ogiela CA, Collins CA, Kym PR. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2. Bioorganic & Medicinal Chemistry Letters. 14: 4879-82. PMID 15341943 DOI: 10.1016/J.Bmcl.2004.07.034  1
2004 Souers AJ, Wodka D, Gao J, Lewis JC, Vasudevan A, Gentles R, Brodjian S, Dayton B, Ogiela CA, Fry D, Hernandez LE, Marsh KC, Collins CA, Kym PR. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1. Bioorganic & Medicinal Chemistry Letters. 14: 4873-7. PMID 15341942 DOI: 10.1016/J.Bmcl.2004.07.032  1
2004 McNally T, Grihalde ND, Pederson TM, Ogiela CA, Djuric SW, Collins CA, Lin CW, Reilly RM. Cloning and characterization of the glucagon receptor from cynomologous monkey. Peptides. 25: 1171-8. PMID 15245877 DOI: 10.1016/J.Peptides.2004.05.008  1
2004 Kurukulasuriya R, Sorensen BK, Link JT, Patel JR, Jae HS, Winn MX, Rohde JR, Grihalde ND, Lin CW, Ogiela CA, Adler AL, Collins CA. Biaryl amide glucagon receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 2047-50. PMID 15080976 DOI: 10.1016/J.Bmcl.2004.02.056  1
2003 Collins CA, Kym PR. Prospects for obesity treatment: MCH receptor antagonists. Current Opinion in Investigational Drugs (London, England : 2000). 4: 386-94. PMID 12808876  1
1995 Tuma PL, Collins CA. Dynamin forms polymeric complexes in the presence of lipid vesicles. Characterization of chemically cross-linked dynamin molecules. The Journal of Biological Chemistry. 270: 26707-14. PMID 7592898 DOI: 10.1074/Jbc.270.44.26707  1
1994 Tuma PL, Collins CA. Activation of dynamin GTPase is a result of positive cooperativity. The Journal of Biological Chemistry. 269: 30842-7. PMID 7983015  1
1993 Tuma PL, Stachniak MC, Collins CA. Activation of dynamin GTPase by acidic phospholipids and endogenous rat brain vesicles. The Journal of Biological Chemistry. 268: 17240-6. PMID 8349610  1
1983 Collins CA, Wells WW. Identification of phosphatidylinositol kinase in rat liver lysosomal membranes Journal of Biological Chemistry. 258: 2130-2134. PMID 6296133  1
1982 Collins CA, Wells WW. Characterization of endogenous protein phosphorylation in isolated rat liver lysosomes Journal of Biological Chemistry. 257: 827-831. PMID 6274866  1
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