Angela Risch - Publications

Affiliations: 
Epigenetics and cancer risk factors German Cancer Research Center (DKFZ), Germany 

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chung FF, Maldonado SG, Nemc A, Bouaoun L, Cahais V, Cuenin C, Salle A, Johnson T, Ergüner B, Laplana M, Datlinger P, Jeschke J, Weiderpass E, Kristensen V, Delaloge S, ... ... Risch A, et al. Buffy coat signatures of breast cancer risk in a prospective cohort study. Clinical Epigenetics. 15: 102. PMID 37309009 DOI: 10.1186/s13148-023-01509-6  0.732
2023 Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Dai J, Hung RJ, Chen K, Shu XO, Kim YT, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, ... ... Risch A, et al. Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population. Nature Communications. 14: 3043. PMID 37236969 DOI: 10.1038/s41467-023-38196-z  0.478
2023 Cheng C, Hong W, Li Y, Xiao X, McKay J, Han Y, Byun J, Peng B, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, ... Risch A, et al. Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 37150255 DOI: 10.1016/j.jtho.2023.05.001  0.561
2022 Faltus C, Lahnsteiner A, Barrdahl M, Assenov Y, Hüsing A, Bogatyrova O, Laplana M, Johnson T, Muley T, Meister M, Warth A, Thomas M, Plass C, Kaaks R, Risch A. Identification of as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS). International Journal of Molecular Sciences. 23. PMID 36142605 DOI: 10.3390/ijms231810699  0.808
2022 Byun J, Han Y, Li Y, Xia J, Long E, Choi J, Xiao X, Zhu M, Zhou W, Sun R, Bossé Y, Song Z, Schwartz A, Lusk C, Rafnar T, ... ... Risch A, et al. Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Nature Genetics. PMID 35915169 DOI: 10.1038/s41588-022-01115-x  0.449
2022 Yang W, Liu H, Zhang R, Freedman JA, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso NE, Landi MT, Brueske I, ... Risch A, et al. Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk. Npj Precision Oncology. 6: 48. PMID 35773316 DOI: 10.1038/s41698-022-00281-9  0.545
2022 Zhang R, Shen S, Wei Y, Zhu Y, Li Y, Chen J, Guan J, Pan Z, Wang Y, Zhu M, Xie J, Xiao X, Zhu D, Li Y, Albanes D, ... ... Risch A, et al. A large-scale genome-wide gene-gene interaction study of lung cancer susceptibility in Europeans with a trans-ethnic validation in Asians. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 35500836 DOI: 10.1016/j.jtho.2022.04.011  0.5
2022 Li Y, Xiao X, Li J, Byun J, Cheng C, Bossé Y, McKay J, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, et al. Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk. Human Molecular Genetics. PMID 35138370 DOI: 10.1093/hmg/ddac030  0.581
2022 Rosenberger A, Muttray N, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Davies MPA, ... ... Risch A, et al. Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer. European Journal of Medical Research. 27: 14. PMID 35101137 DOI: 10.1186/s40001-022-00638-7  0.443
2021 Schamschula E, Lahnsteiner A, Assenov Y, Hagmann W, Zaborsky N, Wiederstein M, Strobl A, Stanke F, Muley T, Plass C, Tümmler B, Risch A. Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in in lung epithelial cells. Epigenetics. 1-24. PMID 34415821 DOI: 10.1080/15592294.2021.1959976  0.438
2021 Lesseur C, Ferreiro-Iglesias A, McKay JD, Bossé Y, Johansson M, Gaborieau V, Landi MT, Christiani DC, Caporaso NC, Bojesen SE, Amos CI, Shete S, Liu G, Rennert G, Albanes D, ... ... Risch A, et al. Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. Plos Genetics. 17: e1009254. PMID 33667223 DOI: 10.1371/journal.pgen.1009254  0.501
2021 Laplana M, Bieg M, Faltus C, Melnik S, Bogatyrova O, Gu Z, Muley T, Meister M, Dienemann H, Herpel E, Amos CI, Schlesner M, Eils R, Plass C, Risch A. Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers. Epigenetics. 1-16. PMID 33595421 DOI: 10.1080/15592294.2021.1878723  0.802
2021 Hung RJ, Warkentin MT, Brhane Y, Chatterjee N, Christiani DC, Landi MT, Caporaso NE, Liu G, Johansson M, Albanes D, Le Marchand L, Tardon A, Rennert G, Bojesen SE, Chen C, ... ... Risch A, et al. Assessing Lung Cancer Absolute Risk Trajectory based on a Polygenic Risk Model. Cancer Research. PMID 33472890 DOI: 10.1158/0008-5472.CAN-20-1237  0.515
2020 Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bossé Y, Lam S, Tsao MS, Tardon A, Chen C, Doherty J, Goodman G, Bojesen SE, Landi MT, ... ... Risch A, et al. Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer. Genetic Epidemiology. PMID 32924180 DOI: 10.1002/Gepi.22358  0.613
2020 Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeböller H, Bojesen SE, Brennan P, Brunnström H, Melander O, Caporaso NE, Landi MT, Chen C, ... ... Risch A, et al. Causal Relationships between Body Mass Index, Smoking, and Lung Cancer: Univariable and Multivariable Mendelian Randomization. International Journal of Cancer. PMID 32914876 DOI: 10.1002/Ijc.33292  0.573
2020 Qin N, Li Y, Wang C, Zhu M, Dai J, Hong T, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojesen SE, Landi MT, Johansson M, Risch A, et al. Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Frontiers of Medicine. PMID 32889700 DOI: 10.1007/S11684-020-0779-4  0.51
2020 Grund-Gröschke S, Ortner D, Szenes-Nagy AB, Zaborsky N, Weiss R, Neureiter D, Wipplinger M, Risch A, Hammerl P, Greil R, Sibilia M, Gratz IK, Stoitzner P, Aberger F. Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity. Molecular Oncology. PMID 32615027 DOI: 10.1002/1878-0261.12758  0.312
2020 Schamschula E, Hagmann W, Assenov Y, Hedtfeld S, Farag AK, Roesner LM, Wiehlmann L, Stanke F, Fischer S, Risch A, Tümmler B. Immunotyping of clinically divergent p.Phe508del homozygous monozygous cystic fibrosis twins. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 32540173 DOI: 10.1016/J.Jcf.2020.06.009  0.307
2020 Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, ... ... Risch A, et al. Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications. 11: 2220. PMID 32393777 DOI: 10.1038/S41467-020-15905-6  0.607
2020 Wang Y, Gorlova OY, Gorlov IP, Zhu M, Dai J, Albanes D, Lam S, Tardon A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, et al. Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32277007 DOI: 10.1158/1055-9965.Epi-19-1085  0.641
2020 Kim-Wanner SZ, Assenov Y, Nair MB, Weichenhan D, Benner A, Becker N, Landwehr K, Kuner R, Sültmann H, Esteller M, Koch I, Lindner M, Meister M, Thomas M, Bieg M, ... ... Risch A, et al. Genome-wide DNA methylation profiling in early stage I lung adenocarcinoma reveals predictive aberrant methylation in the promoter region of the long non-coding RNA PLUT - an exploratory study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 32272161 DOI: 10.1016/J.Jtho.2020.03.023  0.399
2019 Bossé Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeböller H, Bojesen SE, Brennan P, Brunnstrom H, ... ... Risch A, et al. Transcriptome-wide association study reveals candidate causal genes for lung cancer. International Journal of Cancer. PMID 31696517 DOI: 10.1002/Ijc.32771  0.637
2019 Dai J, Huang M, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, Rennert G, Fan J, Goodman G, Liu G, Field JK, Grankvist K, ... ... Risch A, et al. Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk. International Journal of Cancer. PMID 31577861 DOI: 10.1002/Ijc.32698  0.655
2019 Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, ... ... Risch A, et al. Publisher Correction: Shared heritability and functional enrichment across six solid cancers. Nature Communications. 10: 4386. PMID 31548585 DOI: 10.1038/S41467-019-12095-8  0.376
2019 Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK, Ying J, Li Y, Han Y, Ji X, Chen W, Wu X, Gorlov IP, Na J, de Andrade M, Liu G, ... ... Risch A, et al. Lung Cancer Risk in Never Smokers of European Descent is Associated with Genetic Variation in the 515.33 TERT-CLPTM1L Region. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 31009812 DOI: 10.1016/J.Jtho.2019.04.008  0.643
2019 Li Y, Xiao X, Bossé Y, Gorlova O, Gorlov I, Han Y, Byun J, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, ... ... Risch A, et al. Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development. Oncotarget. 10: 1760-1774. PMID 30956756 DOI: 10.18632/Oncotarget.26678  0.602
2019 Zhu Y, Wei Y, Zhang R, Dong X, Shen S, Zhao Y, Bai J, Albanes D, Caporaso NE, Landi MT, Zhu B, Chanock SJ, Gu F, Lam S, Tsao MS, ... ... Risch A, et al. Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30700444 DOI: 10.1158/1055-9965.Epi-18-0356  0.506
2019 Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, ... ... Risch A, et al. Shared heritability and functional enrichment across six solid cancers. Nature Communications. 10: 431. PMID 30683880 DOI: 10.1038/S41467-018-08054-4  0.559
2018 Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, ... ... Risch A, et al. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nature Communications. 9: 3927. PMID 30254314 DOI: 10.1038/S41467-018-05890-2  0.555
2018 Ji X, Bossé Y, Landi MT, Gui J, Xiao X, Qian D, Joubert P, Lamontagne M, Li Y, Gorlov I, de Biasi M, Han Y, Gorlova O, Hung RJ, Wu X, ... ... Risch A, et al. Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Nature Communications. 9: 3221. PMID 30104567 DOI: 10.1038/S41467-018-05074-Y  0.611
2018 Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, ... ... Risch A, et al. Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers. International Journal of Epidemiology. PMID 30059977 DOI: 10.1093/Ije/Dyy140  0.576
2018 Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification. Cell Discovery. 4: 37. PMID 29977599 DOI: 10.1038/S41421-018-0033-2  0.38
2018 Rosenberger A, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Haiman CA, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Kiemeney B, ... ... Risch A, et al. Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners. International Archives of Occupational and Environmental Health. PMID 29971594 DOI: 10.1007/S00420-018-1334-3  0.593
2018 Gampenrieder SP, Rinnerthaler G, Hackl H, Pulverer W, Weinhaeusel A, Ilic S, Hufnagl C, Hauser-Kronberger C, Egle A, Risch A, Greil R. DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer. Theranostics. 8: 2278-2288. PMID 29721079 DOI: 10.7150/Thno.23544  0.377
2017 Feng Y, Wang Y, Liu H, Liu Z, Mills C, Owzar K, Xie J, Han Y, Qian DC, Rj RJH, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, ... ... Risch A, et al. Novel Genetic Variants in the P38MAPK Pathway Gene ZAK and Susceptibility to Lung Cancer. Molecular Carcinogenesis. PMID 29071797 DOI: 10.1002/Mc.22748  0.571
2017 Li Y, Xiao X, Han Y, Gorlova O, Qian D, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, ... ... Risch A, et al. Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. Carcinogenesis. PMID 29059373 DOI: 10.1093/Carcin/Bgx113  0.607
2017 Friedrichs S, Manitz J, Burger P, Amos CI, Risch A, Chang-Claude J, Wichmann HE, Kneib T, Bickeböller H, Hofner B. Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies. Computational and Mathematical Methods in Medicine. 2017: 6742763. PMID 28785300 DOI: 10.1155/2017/6742763  0.443
2017 Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, Wheeler W, Amos CI, Bezieau S, Bickeböller H, Brenner H, Brennan P, Chang-Claude J, Conti DV, Ann Doherty J, ... ... Risch A, et al. Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. International Journal of Cancer. PMID 28699174 DOI: 10.1002/Ijc.30883  0.552
2017 McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, ... ... Risch A, et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nature Genetics. PMID 28604730 DOI: 10.1038/Ng.3892  0.643
2017 Carreras-Torres R, Johansson M, Haycock PC, Wade KH, Relton CL, Martin RM, Davey Smith G, Albanes D, Aldrich MC, Andrew A, Arnold SM, Bickeböller H, Bojesen SE, Brunnström H, Manjer J, ... ... Risch A, et al. Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study. Plos One. 12: e0177875. PMID 28594918 DOI: 10.1371/Journal.Pone.0177875  0.551
2017 Feng Y, Wang Y, Liu H, Liu Z, Mills C, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso NE, Teresa Landi M, ... ... Risch A, et al. Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium. Scientific Reports. 7: 825. PMID 28400551 DOI: 10.1038/S41598-017-00850-0  0.582
2017 Liu H, Liu Z, Wang Y, Stinchcombe TE, Owzar K, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, ... ... Risch A, et al. Functional variants in DCAF4 associated with lung cancer risk in European populations. Carcinogenesis. PMID 28383684 DOI: 10.1093/Carcin/Bgx033  0.618
2017 Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, ... ... Risch A, et al. Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nature Genetics. 49: 651. PMID 28358128 DOI: 10.1038/Ng0417-651A  0.811
2017 Pan Y, Liu H, Wang Y, Kang X, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, ... ... Risch A, et al. Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs. Scientific Reports. 7: 44634. PMID 28304396 DOI: 10.1038/Srep44634  0.615
2017 Rosenberger A, Sohns M, Friedrichs S, Hung RJ, Fehringer G, McLaughlin J, Amos CI, Brennan P, Risch A, Brüske I, Caporaso NE, Landi MT, Christiani DC, Wei Y, Bickeböller H. Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus. Plos One. 12: e0173339. PMID 28273134 DOI: 10.1371/Journal.Pone.0173339  0.504
2017 Yin J, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso N, ... ... Risch A, et al. Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. Molecular Carcinogenesis. PMID 28150878 DOI: 10.1002/Mc.22622  0.623
2017 Toth R, Scherer D, Kelemen LE, Risch A, Hazra A, Balavarca Y, Issa JJ, Moreno V, Eeles RA, Ogino S, Wu X, Ye Y, Hung RJ, Goode EL, Ulrich CM. Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 28115406 DOI: 10.1158/1055-9965.Epi-16-0728  0.493
2017 Faltus C, Assenov Y, Barrdahl M, Laplana M, Bogatyrova O, Hüsing A, Johnson T, Meister M, Muley T, Warth A, Plass C, Kaaks R, Risch A. P2.01-036 Identification of a Novel Oncogenic Ubiquitin Ligase from a Lung Cancer Epigenome-Wide Association Study (EWAS) Journal of Thoracic Oncology. 12: S806-S807. DOI: 10.1016/J.Jtho.2016.11.1088  0.811
2016 Zhou F, Wang Y, Liu H, Ready N, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Brüske I, ... Risch A, et al. Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk - a re-analysis of eight GWASs. Molecular Carcinogenesis. PMID 27805284 DOI: 10.1002/Mc.22585  0.546
2016 Yuan H, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, McLaughlin J, Brhane Y, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso N, ... ... Risch A, et al. A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. Scientific Reports. 6: 34234. PMID 27713484 DOI: 10.1038/Srep34234  0.626
2016 Amos CI, Dennis J, Wang Z, Byun J, Schumacher FR, Gayther SA, Casey G, Hunter DJ, Sellers TA, Gruber SB, Dunning AM, Michailidou K, Fachal L, Doheny K, Spurdle AB, ... ... Risch A, et al. The OncoArray Consortium: a Network for Understanding the Genetic Architecture of Common Cancers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 27697780 DOI: 10.1158/1055-9965.Epi-16-0106  0.489
2016 Baglietto L, Ponzi E, Haycock P, Hodge A, Bianca Assumma M, Jung CH, Chung J, Fasanelli F, Guida F, Campanella G, Chadeau-Hyam M, Grankvist K, Johansson M, Ala U, Provero P, ... ... Risch A, et al. DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk. International Journal of Cancer. PMID 27632354 DOI: 10.1002/Ijc.30431  0.5
2016 Khankari NK, Shu XO, Wen W, Kraft P, Lindström S, Peters U, Schildkraut J, Schumacher F, Bofetta P, Risch A, Bickeböller H, Amos CI, Easton D, Eeles RA, Gruber SB, et al. Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses. Plos Medicine. 13: e1002118. PMID 27598322 DOI: 10.1371/Journal.Pmed.1002118  0.548
2016 Zuber V, Marconett CN, Shi J, Hua X, Wheeler W, Yang C, Song L, Dale AM, Laplana M, Risch A, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, et al. Pleiotropic Analysis of Lung Cancer and Blood Triglycerides. Journal of the National Cancer Institute. 108. PMID 27565901 DOI: 10.1093/Jnci/Djw167  0.817
2016 Chen LS, Baker T, Hung RJ, Horton A, Culverhouse R, Hartz S, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Rosenberger A, Aben KK, ... ... Risch A, et al. Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis. Ebiomedicine. 11: 219-226. PMID 27543155 DOI: 10.1016/J.Ebiom.2016.08.012  0.529
2016 Patel YM, Park SL, Han Y, Wilkens LR, Bickeböller H, Rosenberger A, Caporaso N, Landi MT, Bruske I, Risch A, Wei Y, Christiani DC, Brennan P, Houlston RS, McKay J, et al. Novel Association of Genetic Markers Affecting CYP2A6 activity and Lung Cancer Risk. Cancer Research. PMID 27488534 DOI: 10.1158/0008-5472.Can-16-0446  0.642
2016 Karami S, Han Y, Pande M, Cheng I, Rudd J, Pierce BL, Nutter EL, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Fang S, Han J, Kraft P, Hunter DJ, ... ... Risch A, et al. Telomere structure and maintenance gene variants and risk of five cancer types. International Journal of Cancer. PMID 27459707 DOI: 10.1002/Ijc.30288  0.606
2016 Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, et al. Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Human Genetics. PMID 27264937 DOI: 10.1007/s00439-016-1692-4  0.484
2016 Fehringer G, Kraft P, Pharoah PD, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindstrom S, Brennan P, Bickeböller H, Houlston RS, Landi MT, Caporaso NE, Risch A, Amin Al Olama A, et al. Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations. Cancer Research. PMID 27197191 DOI: 10.1158/0008-5472.Can-15-2980  0.599
2016 Kang X, Liu H, Onaitis MW, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, ... ... Risch A, et al. Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls. Carcinogenesis. PMID 26905588 DOI: 10.1093/Carcin/Bgw014  0.639
2015 Fasanelli F, Baglietto L, Ponzi E, Guida F, Campanella G, Johansson M, Grankvist K, Johansson M, Assumma MB, Naccarati A, Chadeau-Hyam M, Ala U, Faltus C, Kaaks R, Risch A, et al. Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts. Nature Communications. 6: 10192. PMID 26667048 DOI: 10.1038/Ncomms10192  0.587
2015 Rosenberger A, Friedrichs S, Amos CI, Brennan P, Fehringer G, Heinrich J, Hung RJ, Muley T, Müller-Nurasyid M, Risch A, Bickeböller H. META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies. Plos One. 10: e0140179. PMID 26501144 DOI: 10.1371/Journal.Pone.0140179  0.355
2015 Qian DC, Byun J, Han Y, Greene CS, Field JK, Hung RJ, Brhane Y, Mclaughlin JR, Fehringer G, Landi MT, Rosenberger A, Bickeböller H, Malhotra J, Risch A, Heinrich J, et al. Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions. Human Molecular Genetics. PMID 26483192 DOI: 10.1093/Hmg/Ddv440  0.572
2015 Brenner DR, Amos CI, Brhane Y, Timofeeva MN, Caporaso N, Wang Y, Christiani DC, Bickeböller H, Yang P, Albanes D, Stevens VL, Gapstur S, McKay J, Boffetta P, Zaridze D, ... ... Risch A, et al. Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis. PMID 26363033 DOI: 10.1093/Carcin/Bgv128  0.536
2015 Hung RJ, Ulrich CM, Goode EL, Brhane Y, Muir K, Chan AT, Marchand LL, Schildkraut J, Witte JS, Eeles R, Boffetta P, Spitz MR, Poirier JG, Rider DN, Fridley BL, ... ... Risch A, et al. Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. Journal of the National Cancer Institute. 107. PMID 26319099 DOI: 10.1093/Jnci/Djv246  0.549
2015 Zhang C, Doherty JA, Burgess S, Hung RJ, Lindström S, Kraft P, Gong J, Amos C, Sellers TA, Monteiro AN, Chenevix-Trench G, Bickeböller H, Risch A, Brennan P, McKay J, et al. Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study. Human Molecular Genetics. PMID 26138067 DOI: 10.1093/Hmg/Ddv252  0.639
2015 Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, ... ... Risch A, et al. CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis. Journal of the National Cancer Institute. 107. PMID 25873736 DOI: 10.1093/Jnci/Djv100  0.555
2015 Poirier JG, Brennan P, McKay JD, Spitz MR, Bickeböller H, Risch A, Liu G, Le Marchand L, Tworoger S, McLaughlin J, Rosenberger A, Heinrich J, Brüske I, Muley T, Henderson BE, et al. Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Genetic Epidemiology. 39: 197-206. PMID 25644374 DOI: 10.1002/Gepi.21882  0.651
2015 Wrage M, Hagmann W, Kemming D, Uzunoglu FG, Riethdorf S, Effenberger K, Westphal M, Lamszus K, Kim SZ, Becker N, Izbicki JR, Sandoval J, Esteller M, Pantel K, Risch A, et al. Identification of HERC5 and its potential role in NSCLC progression. International Journal of Cancer. Journal International Du Cancer. 136: 2264-72. PMID 25353388 DOI: 10.1002/Ijc.29298  0.571
2015 Scherer D, Toth R, Kelemen L, Risch A, Hazra A, Issa JP, Moreno V, Eeles RA, Quackenbush J, Goode EL, Ogino S, Hung R, Ulrich CM. Abstract 4612: Genetic variants in epigenetic pathways and risk of multiple cancer types in the GAME-ON consortium Cancer Research. 75: 4612-4612. DOI: 10.1158/1538-7445.Am2015-4612  0.595
2015 Karami S, Han Y, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Cheng I, Fang S, Han J, Kraft P, Song F, Hung RJ, McKay J, Chanock SJ, Pande M, ... Risch A, et al. Abstract 4609: Risk loci in telomere structure and maintenance genes across five cancer types: GAME-ON Consortium Cancer Research. 75: 4609-4609. DOI: 10.1158/1538-7445.Am2015-4609  0.565
2014 Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, ... ... Risch A, et al. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nature Genetics. 46: 736-41. PMID 24880342 DOI: 10.1038/Ng.3002  0.821
2014 Reinmuth N, Kloos S, Warth A, Risch A, Muley T, Hoffmann H, Thomas M, Meister M. Insulin-like growth factor 1 pathway mutations and protein expression in resected non-small cell lung cancer. Human Pathology. 45: 1162-8. PMID 24745618 DOI: 10.1016/J.Humpath.2014.01.010  0.462
2014 Park SL, Fesinmeyer MD, Timofeeva M, Caberto CP, Kocarnik JM, Han Y, Love SA, Young A, Dumitrescu L, Lin Y, Goodloe R, Wilkens LR, Hindorff L, Fowke JH, Carty C, ... ... Risch A, et al. Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia. Journal of the National Cancer Institute. 106: dju061. PMID 24681604 DOI: 10.1093/Jnci/Dju061  0.66
2014 Landi MT, Wang Y, Mckay JD, Rafnar T, Wang Z, Timofeeva M, Broderick P, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Houlston RS, Amos CI. Abstract 942: Imputation from The 1000 Genomes Project identifies rare large effect variants of BRCA2-K3326X and CHEK2-I157T as risk factors for lung cancer; a study from the TRICL consortium Cancer Research. 74: 942-942. DOI: 10.1158/1538-7445.Am2014-942  0.635
2013 Freytag S, Manitz J, Schlather M, Kneib T, Amos CI, Risch A, Chang-Claude J, Heinrich J, Bickeböller H. A network-based kernel machine test for the identification of risk pathways in genome-wide association studies. Human Heredity. 76: 64-75. PMID 24434848 DOI: 10.1159/000357567  0.417
2013 Demetriou CA, Chen J, Polidoro S, van Veldhoven K, Cuenin C, Campanella G, Brennan K, Clavel-Chapelon F, Dossus L, Kvaskoff M, Drogan D, Boeing H, Kaaks R, Risch A, Trichopoulos D, et al. Methylome analysis and epigenetic changes associated with menarcheal age. Plos One. 8: e79391. PMID 24278132 DOI: 10.1371/Journal.Pone.0079391  0.337
2013 Sohns M, Viktorova E, Amos CI, Brennan P, Fehringer G, Gaborieau V, Han Y, Heinrich J, Chang-Claude J, Hung RJ, Müller-Nurasyid M, Risch A, Lewinger JP, Thomas DC, Bickeböller H. Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL. Genetic Epidemiology. 37: 551-9. PMID 23893921 DOI: 10.1002/Gepi.21741  0.396
2013 Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, et al. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Human Genetics. 132: 579-89. PMID 23370545 DOI: 10.1007/S00439-013-1270-Y  0.631
2013 Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, Plass C, Risch A. Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4. Oncogene. 32: 3329-38. PMID 22945651 DOI: 10.1038/Onc.2012.344  0.555
2012 Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, ... ... Risch A, et al. Informed conditioning on clinical covariates increases power in case-control association studies. Plos Genetics. 8: e1003032. PMID 23144628 DOI: 10.1371/Journal.Pgen.1003032  0.377
2012 Timofeeva MN, Hung RJ, Rafnar T, Christiani DC, Field JK, Bickeböller H, Risch A, McKay JD, Wang Y, Dai J, Gaborieau V, McLaughlin J, Brenner D, Narod SA, Caporaso NE, et al. Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Human Molecular Genetics. 21: 4980-95. PMID 22899653 DOI: 10.1093/Hmg/Dds334  0.547
2012 Hartz SM, Short SE, Saccone NL, Culverhouse R, Chen L, Schwantes-An TH, Coon H, Han Y, Stephens SH, Sun J, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, ... ... Risch A, et al. Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Archives of General Psychiatry. 69: 854-60. PMID 22868939 DOI: 10.1001/Archgenpsychiatry.2012.124  0.356
2012 Campa D, Müller P, Edler L, Knoefel L, Barale R, Heussel CP, Thomas M, Canzian F, Risch A. A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis. International Journal of Cancer. 131: 2920-8. PMID 22473764 DOI: 10.1002/Ijc.27567  0.524
2012 Han N, Dol Z, Vasieva O, Hyde R, Liloglou T, Raji O, Brambilla E, Brambilla C, Martinet Y, Sozzi G, Risch A, Montuenga LM, Brass A, Field JK. Progressive lung cancer determined by expression profiling and transcriptional regulation. International Journal of Oncology. 41: 242-52. PMID 22469662 DOI: 10.3892/Ijo.2012.1421  0.477
2012 Fehringer G, Liu G, Briollais L, Brennan P, Amos CI, Spitz MR, Bickeböller H, Wichmann HE, Risch A, Hung RJ. Comparison of pathway analysis approaches using lung cancer GWAS data sets. Plos One. 7: e31816. PMID 22363742 DOI: 10.1371/Journal.Pone.0031816  0.416
2012 Rudolph A, Hein R, Hoffmeister M, Försti A, Hemminki K, Risch A, Brenner H, Chang-Claude J. Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy International Journal of Cancer. 131: E841-E848. PMID 22234881 DOI: 10.1002/Ijc.27428  0.433
2011 Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, ... ... Risch A, et al. A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. American Journal of Human Genetics. 88: 861. PMID 28472664 DOI: 10.1016/J.Ajhg.2011.05.003  0.578
2011 Faber K, Glatting KH, Mueller PJ, Risch A, Hotz-Wagenblatt A. Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites. Bmc Bioinformatics. 12: S2. PMID 21992029 DOI: 10.1186/1471-2105-12-S4-S2  0.342
2011 Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, et al. Principles for the post-GWAS functional characterization of cancer risk loci. Nature Genetics. 43: 513-8. PMID 21614091 DOI: 10.1038/Ng.840  0.519
2011 Knoefel LF, Werle-Schneider G, Dally H, Müller PJ, Edler L, Bartsch H, Tuengerthal S, Heussel CP, Reinmuth N, Thomas M, Risch A. Polymorphisms in the apoptotic pathway gene BCL-2 and survival in small cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 183-9. PMID 21107291 DOI: 10.1097/Jto.0B013E3181F8A20E  0.583
2011 Monteiro ANA, Coetzee GA, Freedman ML, Biasi MD, Casey G, Duggan D, Risch A, Plass C, Liu P, James M, Vikis HG, Tichelaar JW, You M, Gayther SA, Mills IG. Principles for the post-GWAS functional characterisation of risk loci Nature Precedings. 1-1. DOI: 10.1038/Npre.2010.5162.1  0.366
2011 Risch A, Schert D, Sarkisyan N, Hagmann W, Bermejo JL, Muley T, Meister M, Dienemann H, Thomas M, Plass C. 1039 POSTER Epigenetic Alterations in Lung Cancer Susceptibility Regions European Journal of Cancer. 47: S107. DOI: 10.1016/S0959-8049(11)70682-7  0.59
2011 Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, ... ... Risch A, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma (The American Journal of Human Genetics (2009) 85 (679-691)) American Journal of Human Genetics. 88: 861. DOI: 10.1016/j.ajhg.2011.05.003  0.489
2010 Landi MT, Chatterjee N, Caporaso NE, Rotunno M, Albanes D, Thun M, Wheeler W, Rosenberger A, Bickeböller H, Risch A, Wang Y, Gaborieau V, Thorgeirsson T, Gudbjartsson D, Sulem P, et al. GPC5 rs2352028 variant and risk of lung cancer in never smokers. The Lancet. Oncology. 11: 714-6; author reply . PMID 20688270 DOI: 10.1016/S1470-2045(10)70096-6  0.573
2010 Truong T, Hung RJ, Amos CI, Wu X, Bickeböller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, et al. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. Journal of the National Cancer Institute. 102: 959-71. PMID 20548021 DOI: 10.1093/Jnci/Djq178  0.617
2010 Truong T, Sauter W, McKay JD, Hosgood HD, Gallagher C, Amos CI, Spitz M, Muscat J, Lazarus P, Illig T, Wichmann HE, Bickeböller H, Risch A, Dienemann H, Zhang ZF, et al. International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants. Carcinogenesis. 31: 625-33. PMID 20106900 DOI: 10.1093/Carcin/Bgq001  0.678
2010 Timofeeva M, Kropp S, Sauter W, Beckmann L, Rosenberger A, Illig T, Jäger B, Mittelstrass K, Dienemann H, Bartsch H, Bickeböller H, Chang-Claude J, Risch A, Wichmann HE. Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer. International Journal of Cancer. 127: 1547-61. PMID 20091863 DOI: 10.1002/Ijc.25175  0.644
2010 Steinbrecher A, Rohrmann S, Timofeeva M, Risch A, Jansen E, Linseisen J. Dietary glucosinolate intake, polymorphisms in selected biotransformation enzymes, and risk of prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 135-43. PMID 20056632 DOI: 10.1158/1055-9965.Epi-09-0660  0.476
2010 Funke S, Timofeeva M, Risch A, Hoffmeister M, Stegmaier C, Seiler CM, Brenner H, Chang-Claude J. Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy. Pharmacogenomics. 11: 33-41. PMID 20017670 DOI: 10.2217/Pgs.09.132  0.473
2010 Scherf DB, Dally H, Müller P, Werle-Schneider G, Jäger B, Edler L, Tuengerthal S, Fischer JR, Drings P, Bartsch H, Risch A. Single nucleotide polymorphisms in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis. The European Respiratory Journal. 35: 381-90. PMID 19643940 DOI: 10.1183/09031936.00125608  0.424
2010 Brenner D, Brennan P, Boffetta P, Amos C, Spitz M, Chen C, Goodman G, Wichmann E, Bickeboller H, Risch A, Benhamou S, Hainault P, Chen G, Witte JS, Hung RJ. Abstract 938: Inflammation and immune response pathway analysis of lung cancer using hierarchal modeling based on GWAS data Cancer Research. 70: 938-938. DOI: 10.1158/1538-7445.Am10-938  0.551
2010 Scherf DB, Sarkisyan NF, Jacobsson HT, Claus R, Bermejo JL, Muley T, Meister M, Dienemann H, Plass C, Risch A. Abstract 4946: The nicotinic acetylcholine receptor genes CHRNA3 and CHRNB4 are epigenetically deregulated in lung tumorigenesis Cancer Research. 70: 4946-4946. DOI: 10.1158/1538-7445.Am10-4946  0.565
2009 Funke S, Risch A, Nieters A, Hoffmeister M, Stegmaier C, Seiler CM, Brenner H, Chang-Claude J. Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy. Journal of Cancer Epidemiology. 2009: 302047. PMID 20445800 DOI: 10.1155/2009/302047  0.404
2009 Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, ... ... Risch A, et al. EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration. The European Respiratory Journal. 34: 1477-86. PMID 19948914 DOI: 10.1183/09031936.00077809  0.57
2009 Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, Mirabello L, Jacobs K, Wheeler W, Yeager M, Bergen AW, Li Q, Consonni D, Pesatori AC, Wacholder S, ... ... Risch A, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. American Journal of Human Genetics. 85: 679-91. PMID 19836008 DOI: 10.1016/J.Ajhg.2009.09.012  0.632
2009 Timofeeva MN, Kropp S, Sauter W, Beckmann L, Rosenberger A, Illig T, Jäger B, Mittelstrass K, Dienemann H, Bartsch H, Bickeböller H, Chang-Claude JC, Risch A, Wichmann HE. CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences. Carcinogenesis. 30: 1161-9. PMID 19414505 DOI: 10.1093/Carcin/Bgp102  0.645
2009 Cote ML, Chen W, Smith DW, Benhamou S, Bouchardy C, Butkiewicz D, Fong KM, Gené M, Hirvonen A, Kiyohara C, Larsen JE, Lin P, Raaschou-Nielsen O, Povey AC, Reszka E, ... Risch A, et al. Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review. American Journal of Epidemiology. 169: 802-14. PMID 19240225 DOI: 10.1093/Aje/Kwn417  0.628
2009 Timofeeva M, Jäger B, Rosenberger A, Sauter W, Wichmann HE, Bickeböller H, Risch A. A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers. Clinical Biochemistry. 42: 500-9. PMID 19161997 DOI: 10.1016/J.Clinbiochem.2008.12.011  0.325
2009 Müller PJ, Dally H, Klappenecker CN, Edler L, Jäger B, Gerst M, Spiegelhalder B, Tuengerthal S, Fischer JR, Drings P, Bartsch H, Risch A. Polymorphisms in ABCG2, ABCC3 and CNT1 genes and their possible impact on chemotherapy outcome of lung cancer patients. International Journal of Cancer. 124: 1669-74. PMID 19107936 DOI: 10.1002/Ijc.23956  0.557
2008 Knöfel LF, Werle-Schneider G, Dally H, Müller PJ, Edler L, Bartsch H, Heussel CP, Thomas M, Risch A. Six single-nucleotide polymorphisms in apoptotic genes and chemotherapy outcome in lung cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3598. PMID 27949374 DOI: 10.1200/Jco.2008.26.15_Suppl.3598  0.452
2008 Hung RJ, Christiani DC, Risch A, Popanda O, Haugen A, Zienolddiny S, Benhamou S, Bouchardy C, Lan Q, Spitz MR, Wichmann HE, LeMarchand L, Vineis P, Matullo G, Kiyohara C, et al. International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 3081-9. PMID 18990748 DOI: 10.1158/1055-9965.Epi-08-0411  0.609
2008 Sauter W, Rosenberger A, Beckmann L, Kropp S, Mittelstrass K, Timofeeva M, Wölke G, Steinwachs A, Scheiner D, Meese E, Sybrecht G, Kronenberg F, Dienemann H, Chang-Claude J, ... ... Risch A, et al. Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 1127-35. PMID 18483334 DOI: 10.1158/1055-9965.Epi-07-2840  0.527
2008 Mittelstrass K, Sauter W, Rosenberger A, Illig T, Timofeeva M, Klopp N, Dienemann H, Meese E, Sybrecht G, Woelke G, Cebulla M, Degen M, Morr H, Drings P, Groeschel A, ... ... Risch A, et al. Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene. Bmc Cancer. 8: 113. PMID 18433484 DOI: 10.1186/1471-2407-8-113  0.551
2008 Risch A, Plass C. Lung cancer epigenetics and genetics. International Journal of Cancer. 123: 1-7. PMID 18425819 DOI: 10.1002/Ijc.23605  0.629
2008 Müller P, Asher N, Heled M, Cohen SB, Risch A, Rund D. Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups. Leukemia Research. 32: 919-29. PMID 18207572 DOI: 10.1016/J.Leukres.2007.10.011  0.304
2008 Timofeeva M, Kropp S, Sauter W, Rosenberger A, Illig T, Dienemann H, Bickeböller H, Chang-Claude J, Risch A, Wichmann H-. Genetic polymorphisms of myeloperoxidase (MPO), epoxide hydrolase 1 (EPHX1) and NAD(P)H dehydrogenase 1 (NQO1) as risk factors of early onset lung caner Ejc Supplements. 6: 205. DOI: 10.1016/S1359-6349(08)71905-0  0.488
2008 Sauter W, Rosenberger A, Beckmann L, Timofeeva M, Mittelstrass K, Illig T, Chang-Claude J, Wichmann HE, Bickeböller H, Risch A. Case-control study of genetic susceptibility in early onset lung cancer: Investigation of Matrix Metalloproteinase-1 (MMP1) Ejc Supplements. 6: 205. DOI: 10.1016/S1359-6349(08)71903-7  0.464
2008 Timofeeva M, Kropp S, Sauter W, Rosenberger A, Illig T, Dienemann H, Bickeböller H, Chang-Claude J, Risch A, Wichmann HE. Glutathione-S-transferase T1, M1 and P1 polymorphisms as risk factors for early onset lung cancer Ejc Supplements. 6: 44. DOI: 10.1016/S1359-6349(08)71344-2  0.538
2007 Taioli E, Benhamou S, Bouchardy C, Cascorbi I, Cajas-Salazar N, Dally H, Fong KM, Larsen JE, Le Marchand L, London SJ, Risch A, Spitz MR, Stucker I, Weinshenker B, Wu X, et al. Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 9: 67-73. PMID 17304047 DOI: 10.1097/Gim.0B013E31803068B1  0.525
2007 Bartsch H, Dally H, Popanda O, Risch A, Schmezer P. Genetic risk profiles for cancer susceptibility and therapy response. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 174: 19-36. PMID 17302182 DOI: 10.1016/S1359-6349(06)80479-9  0.594
2007 Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MW, Pooley KA, Scollen S, Baynes C, Ponder BA, Chanock S, Lissowska J, Brinton L, Peplonska B, Southey MC, Hopper JL, ... ... Risch A, et al. A common coding variant in CASP8 is associated with breast cancer risk. Nature Genetics. 39: 352-8. PMID 17293864 DOI: 10.1038/Ng1981  0.465
2007 Popanda O, Edler L, Waas P, Schattenberg T, Butkiewicz D, Muley T, Dienemann H, Risch A, Bartsch H, Schmezer P. Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms. Lung Cancer (Amsterdam, Netherlands). 55: 25-34. PMID 17059853 DOI: 10.1016/J.Lungcan.2006.09.006  0.537
2007 Lilla C, Risch A, Verla-Tebit E, Hoffmeister M, Brenner H, Chang-Claude J. SULT1A1 genotype and susceptibility to colorectal cancer. International Journal of Cancer. 120: 201-6. PMID 17013894 DOI: 10.1002/Ijc.22156  0.53
2007 Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MWR, Pooley KA, Scollen S, Baynes C, Ponder BAJ, Chanock S, Lissowska J, Brinton L, Peplonska B, Southey MC, Hopper JL, ... ... Risch A, et al. Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk Nature Genetics. 39: 688. DOI: 10.1038/Ng0507-688B  0.434
2006 Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, ... ... Risch A, et al. Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review. American Journal of Epidemiology. 164: 1027-42. PMID 17000715 DOI: 10.1093/Aje/Kwj321  0.618
2006 Lilla C, Verla-Tebit E, Risch A, Jäger B, Hoffmeister M, Brenner H, Chang-Claude J. Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 99-107. PMID 16434594 DOI: 10.1158/1055-9965.Epi-05-0618  0.5
2006 Frullanti E, Forti S, Raimondi S, Benhamou S, Cascorbi I, Marchand LL, London SJ, Risch A, Spitz MR, Stucker I, Yang P, Taioli E. Age and gender differences in the association between MPO 463>A and lung cancer. Results from the genetic susceptibility to environmental carcinogens pooled analysis Gender Medicine. 3. DOI: 10.1016/S1550-8579(06)80103-8  0.572
2006 Dally H, Tuengerthal S, Drings P, Fischer JR, Edler L, Jäger B, Popanda O, Spiegelhalder B, Bartsch H, Risch A. P52. Association of DNA-repair polymorphisms with survival in lung cancer patients Ejc Supplements. 4: 45-46. DOI: 10.1016/J.Ejcsup.2006.04.112  0.552
2005 Raimondi S, Boffetta P, Anttila S, Bröckmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dragani TA, Garte S, Gsur A, Haidinger G, Hirvonen A, Ingelman-Sundberg M, Kalina I, Lan Q, ... ... Risch A, et al. Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study. Mutation Research. 592: 45-57. PMID 16009381 DOI: 10.1016/J.Mrfmmm.2005.06.002  0.636
2005 Becher H, Ramroth H, Ahrens W, Risch A, Schmezer P, Dietz A. Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk. International Journal of Cancer. 116: 451-7. PMID 15810012 DOI: 10.1002/Ijc.21049  0.435
2005 Lilla C, Risch A, Kropp S, Chang-Claude J. SULT1A1 genotype, active and passive smoking, and breast cancer risk by age 50 years in a German case-control study. Breast Cancer Research : Bcr. 7: R229-37. PMID 15743503 DOI: 10.1186/Bcr976  0.44
2004 Butkiewicz D, Popanda O, Risch A, Edler L, Dienemann H, Schulz V, Kayser K, Drings P, Bartsch H, Schmezer P. Association between the risk for lung adenocarcinoma and a (-4) G-to-A polymorphism) in the XPA gene Cancer Epidemiology Biomarkers and Prevention. 13: 2242-2246. PMID 15598786  0.526
2004 Popanda O, Schattenberg T, Phong CT, Butkiewicz D, Risch A, Edler L, Kayser K, Dienemann H, Schulz V, Drings P, Bartsch H, Schmezer P. Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer Carcinogenesis. 25: 2433-2441. PMID 15333465 DOI: 10.1093/Carcin/Bgh264  0.575
2004 Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, ... ... Risch A, et al. Association of metabolic gene polymorphisms with tobacco consumption in healthy controls. International Journal of Cancer. Journal International Du Cancer. 110: 266-70. PMID 15069692 DOI: 10.1002/Ijc.20114  0.358
2004 Dally H, Bartsch H, Jäger B, Edler L, Schmezer P, Spiegelhalder B, Dienemann H, Drings P, Kayser K, Schulz V, Risch A. Genotype relationships in the CYP3A locus in Caucasians. Cancer Letters. 207: 95-9. PMID 15050738 DOI: 10.1016/J.Canlet.2003.12.011  0.508
2004 Lilla C, Risch A, Kropp S, Bartsch H, Chang‐Claude J. P2.20: SULT1A1 genotype, active and passive smoking and breast cancer risk Biometrical Journal. 46: 131-131. DOI: 10.1002/Bimj.200490191  0.438
2004 Kropp S, Risch A, Jäger B, Bartsch H, Chang‐Claude J. S20.4: Genetic Polymorphisms in CYP1A1 and 1B1 and the association between estrogen exposure or tobacco smoke and premenopausal breast cancer risk Biometrical Journal. 46: 44-44. DOI: 10.1002/Bimj.200490094  0.431
2003 Dally H, Edler L, Jäger B, Schmezer P, Spiegelhalder B, Dienemann H, Drings P, Schulz V, Kayser K, Bartsch H, Risch A. The CYP3A4*1B allele increases risk for small cell lung cancer: effect of gender and smoking dose. Pharmacogenetics. 13: 607-18. PMID 14515059 DOI: 10.1097/00008571-200310000-00004  0.591
2003 Dally H, Bartsch H, Risch A. Correspondence re: Feyler et al., Point: Myeloperoxidase (-463)G --> a polymorphism and lung cancer risk. Cancer Epidemiol. Biomark. Prev., 11: 1550-1554, 2002, and Xu et al., Counterpoint: The myeloperoxidase (-463)G --> a polymorphism does not decrease lung cancer susceptibility in Caucasians. 11: 1555-1559, 2002. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 12: 683. PMID 12869414  0.427
2003 Risch A, Ramroth H, Raedts V, Rajaee-Behbahani N, Schmezer P, Bartsch H, Becher H, Dietz A. Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1. Pharmacogenetics. 13: 225-30. PMID 12668919 DOI: 10.1097/00008571-200304000-00007  0.419
2002 Godschalk R, Nair J, van Schooten FJ, Risch A, Drings P, Kayser K, Dienemann H, Bartsch H. Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: Effect of cigarette smoking Carcinogenesis. 23: 2081-2086. PMID 12507931 DOI: 10.1093/Carcin/23.12.2081  0.408
2002 Dally H, Gassner K, Jäger B, Schmezer P, Spiegelhalder B, Edler L, Drings P, Dienemann H, Schulz V, Kayser K, Bartsch H, Risch A. Myeloperoxidase (MPO) genotype and lung cancer histologic types: the MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers. International Journal of Cancer. 102: 530-5. PMID 12432558 DOI: 10.1002/Ijc.10756  0.643
2001 Risch A, Wikman H, Thiel S, Schmezer P, Edler L, Drings P, Dienemann H, Kayser K, Schulz V, Spiegelhalder B, Bartsch H. Glutathione-S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small-cell lung cancer subtypes and hamartomas Pharmacogenetics. 11: 757-764. PMID 11740339 DOI: 10.1097/00008571-200112000-00003  0.633
2001 Godschalk RWL, Dallinga JW, Wikman H, Risch A, Kleinjans JCS, Bartsch H, Schooten FV. Modulation of DNA and protein adducts in smokers by genetic polymorphisms in GSTM1,GSTT1, NAT1 and NAT2. Pharmacogenetics. 11: 389-398. PMID 11470992 DOI: 10.1097/00008571-200107000-00003  0.343
2001 Wikman H, Thiel S, Jäger B, Schmezer P, Spiegelhalder B, Edler L, Dienemann H, Kayser K, Schulz V, Drings P, Bartsch H, Risch A. Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility. Pharmacogenetics. 11: 157-68. PMID 11266080 DOI: 10.1097/00008571-200103000-00006  0.605
2001 Rajaee-Behbahani N, Schmezer P, Risch A, Rittgen W, Kayser KW, Dienemann H, Schulz V, Drings P, Thiel S, Bartsch H. Altered DNA repair capacity and bleomycin sensitivity as risk markers for non-small cell lung cancer International Journal of Cancer. 95: 86-91. PMID 11241317 DOI: 10.1002/1097-0215(20010320)95:2<86::Aid-Ijc1015>3.0.Co;2-B  0.48
2001 Schmezer P, Rajaee-Behbahani N, Risch A, Thielm S, Rittgen W, Drings P, Dienemann H, Kayser KW, Schulz V, Bartsch H. Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes Mutagenesis. 16: 25-30. PMID 11139596 DOI: 10.1093/Mutage/16.1.25  0.462
2000 Wikman H, Risch A, Klimek F, Schmezer P, Spiegelhalder B, Dienemann H, Kayser K, Schulz V, Drings P, Bartsch H. hOGG1 polymorphism and loss of heterozygosity (LOH): Significance for lung cancer susceptibility in a Caucasian population International Journal of Cancer. 88: 932-937. PMID 11093817 DOI: 10.1002/1097-0215(20001215)88:6<932::Aid-Ijc15>3.0.Co;2-P  0.568
1999 Thygesen P, Risch A, Stacey M, Fakis G, Giannoulis F, Takle L, Knowles M, Sim E. Genes for human arylamine N-acetyltransferases in relation to loss of the short arm of chromosome 8 in bladder cancer. Pharmacogenetics. 9: 1-8. PMID 10208636 DOI: 10.1097/00008571-199902000-00001  0.418
1999 Wikman H, Thiel S, Schmezer P, Drings P, Dienemann H, Kayser K, Schulz V, Spiegelhalder B, Bartsch H, Risch A. Genetic polymorphisms in GSTs and individual susceptibility to lung cancer Lung Cancer. 25. DOI: 10.1016/S0169-5002(99)90723-7  0.595
1998 Bartsch H, Rojas M, Alexandrov K, Risch A. Impact of adduct determination on the assessment of cancer susceptibility. Recent Results in Cancer Research. 154: 86-96. PMID 10026994 DOI: 10.1007/978-3-642-46870-4_5  0.577
1997 Matas N, Thygesen P, Stacey M, Risch A, Sim E. Mapping AAC1, AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours Cytogenetic and Genome Research. 77: 290-295. PMID 9284941 DOI: 10.1159/000134601  0.345
1997 Bartsch H, Risch A, Schmezer P, Velic I, Schwarz M. DNA Damage from Endogenous Processes, Workshop: 16-17 September 1996, German Cancer Research Centre Heidelberg, Germany. Journal of Cancer Research and Clinical Oncology. 123: 232-234. PMID 9177497 DOI: 10.1007/Bf01240321  0.357
1996 Stacey M, Thygesen P, Stanley L, Matas N, Risch A, Sim E. Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies. Biomarkers. 1: 55-61. PMID 23888894 DOI: 10.3109/13547509609079347  0.324
1995 Risch A, Wallace DM, Bathers S, Sim E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Human Molecular Genetics. 4: 231-236. PMID 7757072 DOI: 10.1093/Hmg/4.2.231  0.511
1995 Risch A, Bathers S, Wallace D, Smith J, Sim E. N-acetyltransferase-type 2 genotype in occupational bladder cancer Toxicology Letters. 78: 70-71. DOI: 10.1016/0378-4274(95)94913-2  0.328
1994 Hickman D, Risch A, Buckle V, Spurr NK, Jeremiah SJ, McCarthy A, Sim E. Chromosomal localization of human genes for arylamine N-acetyltransferase Biochemical Journal. 297: 441-445. PMID 8110178 DOI: 10.1042/Bj2970441  0.358
1992 Hickman D, Risch A, Camilleri JP, Sim E. Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants. Pharmacogenetics. 2: 217-226. PMID 1306121 DOI: 10.1097/00008571-199210000-00004  0.332
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