| Year |
Citation |
Score |
| 2023 |
Eisenreichova A, Humpolickova J, Różycki B, Boura E, Koukalova A. Effects of biophysical membrane properties on recognition of phosphatidylserine, or phosphatidylinositol 4-phosphate by lipid biosensors LactC2, or P4M. Biochimie. 215: 42-49. PMID 37683994 DOI: 10.1016/j.biochi.2023.09.003 |
0.372 |
|
| 2023 |
Eisenreichova A, Klima M, Anila MM, Koukalova A, Humpolickova J, Różycki B, Boura E. Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport. Cells. 12. PMID 37566053 DOI: 10.3390/cells12151974 |
0.385 |
|
| 2020 |
Krafcikova P, Silhan J, Nencka R, Boura E. Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin. Nature Communications. 11: 3717. PMID 32709887 DOI: 10.1038/S41467-020-17495-9 |
0.38 |
|
| 2020 |
Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19. Journal of Biomolecular Structure & Dynamics. 1-12. PMID 32567979 DOI: 10.1080/07391102.2020.1778535 |
0.326 |
|
| 2020 |
Konkolova E, Klima M, Nencka R, Boura E. Structural analysis of the putative SARS-CoV-2 primase complex. Journal of Structural Biology. 107548. PMID 32535228 DOI: 10.1016/J.Jsb.2020.107548 |
0.41 |
|
| 2020 |
Pemberton JG, Kim YJ, Humpolickova J, Eisenreichova A, Sengupta N, Toth DJ, Boura E, Balla T. Defining the subcellular distribution and metabolic channeling of phosphatidylinositol. The Journal of Cell Biology. 219. PMID 32211894 DOI: 10.1083/Jcb.201906130 |
0.46 |
|
| 2019 |
Smola M, Horova V, Boura E, Klima M. Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses. Archives of Virology. PMID 31845156 DOI: 10.1007/S00705-019-04490-9 |
0.331 |
|
| 2019 |
Novotná B, Vaneková L, Zavřel M, Buděšínský M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Pimková Polidarová M, Brázdová A, Liboska R, Štěpánek I, Vavrina Z, Jandušík T, Nencka R, et al. Enzymatic Preparation of 2'-5', 3'-5'Cyclic Dinucleotides, Their Binding Properties to STING Adaptor Protein, and Structure/Activity Correlations. Journal of Medicinal Chemistry. PMID 31715099 DOI: 10.1021/Acs.Jmedchem.9B01062 |
0.38 |
|
| 2019 |
Chalupska D, RóŻycki B, Klima M, Boura E. Structural insights into ACBD3 hijacking by picornaviruses. Protein Science : a Publication of the Protein Society. PMID 31583778 DOI: 10.1002/Pro.3738 |
0.384 |
|
| 2019 |
Smola M, Birkus G, Boura E. No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides. Acta Crystallographica. Section F, Structural Biology Communications. 75: 593-598. PMID 31475926 DOI: 10.1107/S2053230X19010999 |
0.344 |
|
| 2019 |
Dubankova A, Horova V, Klima M, Boura E. Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. Journal of Structural Biology. PMID 31415898 DOI: 10.1016/J.Jsb.2019.08.004 |
0.317 |
|
| 2019 |
Horova V, Lyoo H, Różycki B, Chalupska D, Smola M, Humpolickova J, Strating JRPM, van Kuppeveld FJM, Boura E, Klima M. Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathogens. 15: e1007962. PMID 31381608 DOI: 10.1371/Journal.Ppat.1007962 |
0.345 |
|
| 2019 |
Dubankova A, Boura E. Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses. Antiviral Research. 169: 104536. PMID 31202975 DOI: 10.1016/J.Antiviral.2019.104536 |
0.372 |
|
| 2019 |
Chalupska D, Różycki B, Humpolickova J, Faltova L, Klima M, Boura E. Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins. Scientific Reports. 9: 567. PMID 30679637 DOI: 10.1038/S41598-018-37158-6 |
0.416 |
|
| 2019 |
Sengupta N, Jović M, Barnaeva E, Kim DW, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer M, Marugan J, Balla T. A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha. Journal of Lipid Research. PMID 30626625 DOI: 10.1194/Jlr.D090159 |
0.384 |
|
| 2019 |
Novotna B, Vanekova L, Zavrel M, Budesinsky M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Polidarova MP, Brazdova A, Liboska R, Stepanek I, Vavrina Z, Jandusik T, Nencka R, ... ... Boura E, et al. Enzymatic Preparation of 2'-5', 3'-5'Cyclic Dinucleotides, Their Binding Properties to STING Adaptor Protein, and Structure/Activity Correlations. Journal of Medicinal Chemistry. DOI: 10.2210/Pdb6S27/Pdb |
0.354 |
|
| 2018 |
Šebera J, Dubankova A, Sychrovský V, Ruzek D, Boura E, Nencka R. The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors. Scientific Reports. 8: 11132. PMID 30042483 DOI: 10.1038/S41598-018-29459-7 |
0.308 |
|
| 2018 |
Sohn M, Korzeniowski M, Zewe JP, Wills RC, Hammond GRV, Humpolickova J, Vrzal L, Chalupska D, Veverka V, Fairn GD, Boura E, Balla T. PI(4,5)Pcontrols plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. The Journal of Cell Biology. PMID 29472386 DOI: 10.1083/Jcb.201710095 |
0.39 |
|
| 2018 |
Peti W, Page R, Boura E, Różycki B. Structures of Dynamic Protein Complexes: Hybrid Techniques to Study MAP Kinase Complexes and the ESCRT System. Methods in Molecular Biology (Clifton, N.J.). 1688: 375-389. PMID 29151218 DOI: 10.1007/978-1-4939-7386-6_17 |
0.347 |
|
| 2017 |
Dubankova A, Humpolickova J, Klima M, Boura E. Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D . Scientific Reports. 7: 17309. PMID 29230036 DOI: 10.1038/S41598-017-17621-6 |
0.473 |
|
| 2017 |
Chalupska D, Eisenreichova A, Różycki B, Rezabkova L, Humpolickova J, Klima M, Boura E. Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro. Journal of Structural Biology. 200: 36-44. PMID 28864297 DOI: 10.1016/J.Jsb.2017.08.006 |
0.492 |
|
| 2017 |
Hercik K, Brynda J, Nencka R, Boura E. Structural basis of Zika virus methyltransferase inhibition by sinefungin. Archives of Virology. 162: 2091-2096. PMID 28357511 DOI: 10.1007/S00705-017-3345-X |
0.373 |
|
| 2017 |
Boura E, Baumlova A, Chalupska D, Dubankova A, Klima M. Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography. Protein Science : a Publication of the Protein Society. 26: 1116-1123. PMID 28342173 DOI: 10.1002/Pro.3162 |
0.363 |
|
| 2017 |
Klima M, Chalupska D, Różycki B, Humpolickova J, Rezabkova L, Silhan J, Baumlova A, Dubankova A, Boura E. Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein. Structure (London, England : 1993). 25: 219-230. PMID 28065508 DOI: 10.1016/J.Str.2016.11.021 |
0.456 |
|
| 2017 |
Humpolickova J, Mejdrová I, Matousova M, Nencka R, Boura E. Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB). Journal of Medicinal Chemistry. 60: 119-127. PMID 28004946 DOI: 10.1021/Acs.Jmedchem.6B01466 |
0.324 |
|
| 2016 |
Mejdrová I, Chalupská D, Plačková P, Müller C, Šála M, Klíma M, Baumlová A, Hřebabecký H, Procházková E, Dejmek M, Strunin D, Weber J, Lee G, Matoušová M, Mertlíková-Kaiserová H, ... ... Boura E, et al. Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. Journal of Medicinal Chemistry. PMID 28004945 DOI: 10.1021/Acs.Jmedchem.6B01465 |
0.385 |
|
| 2016 |
Eisenreichova A, Klima M, Boura E. Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation. Acta Crystallographica. Section F, Structural Biology Communications. 72: 799-803. PMID 27827352 DOI: 10.1107/S2053230X16015053 |
0.428 |
|
| 2016 |
Klima M, Tóth DJ, Hexnerova R, Baumlova A, Chalupska D, Tykvart J, Rezabkova L, Sengupta N, Man P, Dubankova A, Humpolickova J, Nencka R, Veverka V, Balla T, Boura E. Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein. Scientific Reports. 6: 23641. PMID 27009356 DOI: 10.1038/Srep23641 |
0.543 |
|
| 2016 |
Klima M, Tóth DJ, Hexnerova R, Baumlova A, Chalupska D, Tykvart J, Rezabkova L, Sengupta N, Man P, Dubankova A, Humpolickova J, Nencka R, Veverka V, Balla T, Boura E. Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein Scientific Reports. 6. DOI: 10.1038/srep23641 |
0.462 |
|
| 2015 |
Boura E, Nencka R. Phosphatidylinositol 4-kinases: Function, structure, and inhibition. Experimental Cell Research. 337: 136-45. PMID 26183104 DOI: 10.1016/J.Yexcr.2015.03.028 |
0.443 |
|
| 2015 |
Klima M, Baumlova A, Chalupska D, Hřebabecký H, Dejmek M, Nencka R, Boura E. The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design. Acta Crystallographica. Section D, Biological Crystallography. 71: 1555-63. PMID 26143926 DOI: 10.1107/S1399004715009505 |
0.375 |
|
| 2015 |
Mejdrová I, Chalupská D, Kögler M, Šála M, Pla?ková P, Baumlová A, H?ebabecký H, Procházková E, Dejmek M, Guillon R, Strunin D, Weber J, Lee G, Birkus G, Mertlíková-Kaiserová H, ... Boura E, et al. Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. Journal of Medicinal Chemistry. 58: 3767-93. PMID 25897704 DOI: 10.1021/Acs.Jmedchem.5B00499 |
0.396 |
|
| 2014 |
Różycki B, Boura E. Large, dynamic, multi-protein complexes: a challenge for structural biology. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 26: 463103. PMID 25335513 DOI: 10.1088/0953-8984/26/46/463103 |
0.37 |
|
| 2014 |
Baumlova A, Chalupska D, Ró?ycki B, Jovic M, Wisniewski E, Klima M, Dubankova A, Kloer DP, Nencka R, Balla T, Boura E. The crystal structure of the phosphatidylinositol 4-kinase IIα. Embo Reports. 15: 1085-92. PMID 25168678 DOI: 10.15252/Embr.201438841 |
0.451 |
|
| 2014 |
Jovi? M, Kean MJ, Dubankova A, Boura E, Gingras AC, Brill JA, Balla T. Endosomal sorting of VAMP3 is regulated by PI4K2A. Journal of Cell Science. 127: 3745-56. PMID 25002402 DOI: 10.1242/Jcs.148809 |
0.464 |
|
| 2013 |
Nemecek D, Plevka P, Boura E. Using cryoEM reconstruction and phase extension to determine crystal structure of bacteriophage ϕ6 major capsid protein. The Protein Journal. 32: 635-40. PMID 24293129 DOI: 10.1007/S10930-013-9526-X |
0.338 |
|
| 2013 |
Nemecek D, Boura E, Wu W, Cheng N, Plevka P, Qiao J, Mindich L, Heymann JB, Hurley JH, Steven AC. Subunit folds and maturation pathway of a dsRNA virus capsid. Structure (London, England : 1993). 21: 1374-83. PMID 23891288 DOI: 10.1016/J.Str.2013.06.007 |
0.558 |
|
| 2012 |
Różycki B, Boura E, Hurley JH, Hummer G. Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes. Plos Computational Biology. 8: e1002736. PMID 23093927 DOI: 10.1371/Journal.Pcbi.1002736 |
0.617 |
|
| 2012 |
Boura E, Ivanov V, Carlson LA, Mizuuchi K, Hurley JH. Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers. The Journal of Biological Chemistry. 287: 28144-51. PMID 22718754 DOI: 10.1074/Jbc.M112.378646 |
0.712 |
|
| 2012 |
Baskaran S, Ragusa MJ, Boura E, Hurley JH. Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy. Molecular Cell. 47: 339-48. PMID 22704557 DOI: 10.1016/J.Molcel.2012.05.027 |
0.725 |
|
| 2012 |
Boura E, Różycki B, Chung HS, Herrick DZ, Canagarajah B, Cafiso DS, Eaton WA, Hummer G, Hurley JH. Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (London, England : 1993). 20: 874-86. PMID 22579254 DOI: 10.1016/J.Str.2012.03.008 |
0.614 |
|
| 2012 |
Noinaj N, Easley NC, Oke M, Mizuno N, Gumbart J, Boura E, Steere AN, Zak O, Aisen P, Tajkhorshid E, Evans RW, Gorringe AR, Mason AB, Steven AC, Buchanan SK. Structural basis for iron piracy by pathogenic Neisseria. Nature. 483: 53-8. PMID 22327295 DOI: 10.1038/Nature10823 |
0.369 |
|
| 2012 |
Boura E, Hurley JH. Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit. Proceedings of the National Academy of Sciences of the United States of America. 109: 1901-6. PMID 22232651 DOI: 10.1073/Pnas.1117597109 |
0.636 |
|
| 2011 |
Boura E, Rózycki B, Herrick DZ, Chung HS, Vecer J, Eaton WA, Cafiso DS, Hummer G, Hurley JH. Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 9437-42. PMID 21596998 DOI: 10.1073/Pnas.1101763108 |
0.587 |
|
| 2011 |
Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J. Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner. Cancer Research. 71: 946-54. PMID 21245099 DOI: 10.1158/0008-5472.Can-10-2203 |
0.311 |
|
| 2010 |
Hurley JH, Boura E, Carlson LA, Różycki B. Membrane budding. Cell. 143: 875-87. PMID 21145455 DOI: 10.1016/j.cell.2010.11.030 |
0.716 |
|
| 2010 |
Boura E, Rezabkova L, Brynda J, Obsilova V, Obsil T. Structure of the human FOXO4-DBD-DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA. Acta Crystallographica. Section D, Biological Crystallography. 66: 1351-7. PMID 21123876 DOI: 10.1107/S0907444910042228 |
0.323 |
|
| 2010 |
Rezabkova L, Boura E, Herman P, Vecer J, Bourova L, Sulc M, Svoboda P, Obsilova V, Obsil T. 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3). Journal of Structural Biology. 170: 451-61. PMID 20347994 DOI: 10.1016/J.Jsb.2010.03.009 |
0.357 |
|
| 2009 |
Im YJ, Wollert T, Boura E, Hurley JH. Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. Developmental Cell. 17: 234-43. PMID 19686684 DOI: 10.1016/J.Devcel.2009.07.008 |
0.609 |
|
| 2008 |
Obsilova V, Nedbalkova E, Silhan J, Boura E, Herman P, Vecer J, Sulc M, Teisinger J, Dyda F, Obsil T. The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase Biochemistry. 47: 1768-1777. PMID 18181650 DOI: 10.1021/Bi7019468 |
0.379 |
|
| 2007 |
Boura E, Silhan J, Herman P, Vecer J, Sulc M, Teisinger J, Obsilova V, Obsil T. Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding Journal of Biological Chemistry. 282: 8265-8275. PMID 17244620 DOI: 10.1074/Jbc.M605682200 |
0.332 |
|
| 2005 |
Obsilova V, Vecer J, Herman P, Pabianova A, Sulc M, Teisinger J, Boura E, Obsil T. 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4 Biochemistry. 44: 11608-11617. PMID 16114898 DOI: 10.1021/Bi050618R |
0.372 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Boura E, Nencka R. Corrigendum to: ‘‘Phosphatidylinositol 4-kinases: Function, structure, and inhibition’’ [Exp. Cell Res. 337/2 (2015) 136–145] Experimental Cell Research. 341: 110. DOI: 10.1016/J.Yexcr.2015.11.018 |
0.298 |
|
| 2017 |
Hercík K, Kozak J, Šála M, Dejmek M, Hřebabecký H, Zborníková E, Smola M, Ruzek D, Nencka R, Boura E. Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase. Antiviral Research. 137: 131-133. PMID 27902932 DOI: 10.1016/J.Antiviral.2016.11.020 |
0.288 |
|
| 2020 |
Konkolova E, Dejmek M, Hřebabecký H, Šála M, Böserle J, Nencka R, Boura E. Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses. Antiviral Research. 182: 104899. PMID 32763313 DOI: 10.1016/J.Antiviral.2020.104899 |
0.275 |
|
| 2021 |
Dostalik P, Krafcikova P, Silhan J, Kozic J, Chalupska D, Chalupsky K, Boura E. Structural analysis of the OC43 coronavirus 2'-O-RNA methyltransferase. Journal of Virology. PMID 34011548 DOI: 10.1128/JVI.00463-21 |
0.272 |
|
| 2018 |
Silhan J, Zhao Q, Boura E, Thomson H, Förster A, Tang CM, Freemont PS, Baldwin GS. Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Research. PMID 30329088 DOI: 10.2210/Pdb6Fke/Pdb |
0.271 |
|
| 2010 |
Huerfano S, Zíla V, Boura E, Spanielová H, Stokrová J, Forstová J. Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection. The Febs Journal. 277: 1270-83. PMID 20121946 DOI: 10.1111/J.1742-4658.2010.07558.X |
0.271 |
|
| 2015 |
Dejmek M, Šála M, Hřebabecký H, Dračínský M, Procházková E, Chalupská D, Klíma M, Plačková P, Hájek M, Andrei G, Naesens L, Leyssen P, Neyts J, Balzarini J, Boura E, et al. Norbornane-based nucleoside and nucleotide analogues locked in North conformation. Bioorganic & Medicinal Chemistry. 23: 184-91. PMID 25435471 DOI: 10.1016/J.Bmc.2014.11.011 |
0.269 |
|
| 2021 |
Eisenreichova A, Różycki B, Boura E, Humpolickova J. Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase. Frontiers in Molecular Biosciences. 8: 747601. PMID 34712698 DOI: 10.3389/fmolb.2021.747601 |
0.268 |
|
| 2016 |
Baumlova A, Gregor J, Boura E. The structural basis for calcium inhibition of lipid kinase PI4K IIalpha and comparison with the apo state. Physiological Research. 65: 987-993. PMID 27539108 DOI: 10.33549/PHYSIOLRES.933344 |
0.264 |
|
| 2022 |
Klima M, Khalili Yazdi A, Li F, Chau I, Hajian T, Bolotokova A, Kaniskan HÜ, Han Y, Wang K, Li D, Luo M, Jin J, Boura E, Vedadi M. Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16. Protein Science : a Publication of the Protein Society. 31: e4395. PMID 36040262 DOI: 10.1002/pro.4395 |
0.262 |
|
| 2020 |
Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E. Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein. Plos Pathogens. 16: e1009100. PMID 33264373 DOI: 10.1371/journal.ppat.1009100 |
0.26 |
|
| 2022 |
Różycki B, Boura E. Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data. Biophysical Chemistry. 288: 106843. PMID 35696898 DOI: 10.1016/j.bpc.2022.106843 |
0.252 |
|
| 2022 |
Misehe M, Klima M, Matoušová M, Chalupská D, Dejmek M, Šála M, Mertlíková-Kaiserová H, Boura E, Nencka R. Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorganic & Medicinal Chemistry Letters. 76: 129010. PMID 36184029 DOI: 10.1016/j.bmcl.2022.129010 |
0.249 |
|
| 2022 |
Eisenreichova A, Boura E. Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins. Journal of Structural Biology. 214: 107879. PMID 35781025 DOI: 10.1016/j.jsb.2022.107879 |
0.248 |
|
| 2023 |
Nigam A, Hurley MFD, Li F, KonkoĬová E, Klíma M, Trylčová J, Pollice R, Çinaroğlu SS, Levin-Konigsberg R, Handjaya J, Schapira M, Chau I, Perveen S, Ng HL, Kaniskan HÜ, ... ... Boura E, et al. Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors. Biorxiv : the Preprint Server For Biology. PMID 37873443 DOI: 10.1101/2023.10.03.560722 |
0.247 |
|
| 2020 |
Selvaraj C, Dinesh DC, Panwar U, Boura E, Singh SK. High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 33306471 DOI: 10.1109/TCBB.2020.3037136 |
0.241 |
|
| 2021 |
Novotná B, Holá L, Staś M, Gutten O, Smola M, Zavřel M, Vavřina Z, Buděšínský M, Liboska R, Chevrier F, Dobiaš J, Boura E, Rulíšek L, Birkuš G. Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. Biochemistry. 60: 3714-3727. PMID 34788017 DOI: 10.1021/acs.biochem.1c00692 |
0.229 |
|
| 2023 |
Skvara P, Chalupska D, Klima M, Kozic J, Silhan J, Boura E. Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39. Antiviral Research. 105663. PMID 37421984 DOI: 10.1016/j.antiviral.2023.105663 |
0.222 |
|
| 2023 |
Silhan J, Klima M, Otava T, Skvara P, Chalupska D, Chalupsky K, Kozic J, Nencka R, Boura E. Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase. Nature Communications. 14: 2259. PMID 37080993 DOI: 10.1038/s41467-023-38019-1 |
0.219 |
|
| 2023 |
Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. Structural elucidation of recombinant 20S proteasome bound to covalent inhibitors. Biorxiv : the Preprint Server For Biology. PMID 37645851 DOI: 10.1101/2023.08.17.553660 |
0.215 |
|
| 2023 |
Duchoslav V, Boura E. Structure of monkeypox virus poxin: implications for drug design. Archives of Virology. 168: 192. PMID 37378908 DOI: 10.1007/s00705-023-05824-4 |
0.211 |
|
| 2021 |
Rulíšek L, Smola M, Gutten O, Dejmek M, Kožíšek M, Evangelidis T, Tehrani ZA, Novotná B, Nencka R, Birkuš G, Boura E. Ligand Strain and Its Conformational Complexity Is a Major Factor Determining Binding of Cyclic Dinucleotides to STING Protein. Angewandte Chemie (International Ed. in English). PMID 33616279 DOI: 10.1002/anie.202016805 |
0.207 |
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| 2022 |
Nencka R, Silhan J, Klima M, Otava T, Kocek H, Krafcikova P, Boura E. Coronaviral RNA-methyltransferases: function, structure and inhibition. Nucleic Acids Research. 50: 635-650. PMID 35018474 DOI: 10.1093/nar/gkab1279 |
0.206 |
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| 2021 |
Otava T, Šála M, Li F, Fanfrlík J, Devkota K, Perveen S, Chau I, Pakarian P, Hobza P, Vedadi M, Boura E, Nencka R. The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors. Acs Infectious Diseases. PMID 34152728 DOI: 10.1021/acsinfecdis.1c00131 |
0.206 |
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| 2021 |
Horova V, Landova B, Hodek J, Chalupsky K, Krafcikova P, Chalupska D, Duchoslav V, Weber J, Boura E, Klima M. Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit. Viruses. 13. PMID 34452352 DOI: 10.3390/v13081487 |
0.193 |
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| 2022 |
Dejmek M, Šála M, Brazdova A, Vanekova L, Smola M, Klíma M, Břehová P, Buděšínský M, Dračínský M, Procházková E, Zavřel M, Šimák O, Páv O, Boura E, Birkuš G, et al. Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential. Structure (London, England : 1993). PMID 35690061 DOI: 10.1016/j.str.2022.05.012 |
0.189 |
|
| 2016 |
Boura E, Nencka R. Corrigendum to: ''Phosphatidylinositol 4-kinases: Function, structure, and inhibition'' [Exp. Cell Res. 337/2 (2015) 136-145]. Experimental Cell Research. 341: 110. PMID 33096590 DOI: 10.1016/j.yexcr.2015.11.018 |
0.186 |
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| 2022 |
Vavřina Z, Perlíková P, Milisavljević N, Chevrier F, Smola M, Smith J, Dejmek M, Havlíček V, Buděšínský M, Liboska R, Vaneková L, Brynda J, Boura E, Řezáčová P, Hocek M, et al. Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists. Journal of Medicinal Chemistry. PMID 36201304 DOI: 10.1021/acs.jmedchem.2c01305 |
0.183 |
|
| 2019 |
Dinesh DC, Tamilarasan S, Rajaram K, Bouřa E. Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases. Current Drug Targets. PMID 31538891 DOI: 10.2174/1389450119666190920153247 |
0.181 |
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| 2023 |
Misehe M, Šála M, Matoušová M, Hercík K, Kocek H, Chalupská D, Chaloupecká E, Hájek M, Boura E, Mertlíková-Kaiserová H, Nencka R. Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 129567. PMID 38008339 DOI: 10.1016/j.bmcl.2023.129567 |
0.178 |
|
| 2021 |
Vavřina Z, Gutten O, Smola M, Zavřel M, Aliakbar Tehrani Z, Charvát V, Kožíšek M, Boura E, Birkuš G, Rulíšek L. Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory. Biochemistry. PMID 33586948 DOI: 10.1021/acs.biochem.0c00949 |
0.177 |
|
| 2023 |
Misehe M, Matoušová M, Dvořáková A, Hercík K, Škach K, Chalupská D, Dejmek M, Šála M, Hájek M, Boura E, Mertlíková-Kaiserová H, Nencka R. Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases. European Journal of Medicinal Chemistry. 260: 115717. PMID 37598483 DOI: 10.1016/j.ejmech.2023.115717 |
0.169 |
|
| 2023 |
Li F, Ghiabi P, Hajian T, Klima M, Li ASM, Khalili Yazdi A, Chau I, Loppnau P, Kutera M, Seitova A, Bolotokova A, Hutchinson A, Perveen S, Boura E, Vedadi M. SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses. Biochimica Et Biophysica Acta. General Subjects. 1867: 130319. PMID 36764586 DOI: 10.1016/j.bbagen.2023.130319 |
0.168 |
|
| 2020 |
Selvaraj C, Panwar U, Dinesh DC, Boura E, Singh P, Dubey VK, Singh SK. Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease. Frontiers in Chemistry. 8: 595273. PMID 33585398 DOI: 10.3389/fchem.2020.595273 |
0.167 |
|
| 2021 |
Dejmek M, Konkoľová E, Eyer L, Straková P, Svoboda P, Šála M, Krejčová K, Růžek D, Boura E, Nencka R. Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication. Viruses. 13. PMID 34452451 DOI: 10.3390/v13081585 |
0.159 |
|
| 2022 |
Huskova A, Dinesh DC, Srb P, Boura E, Veverka V, Silhan J. Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model. Nucleic Acids Research. PMID 36155818 DOI: 10.1093/nar/gkac793 |
0.159 |
|
| 2021 |
Milisavljevic N, Konkolová E, Kozák J, Hodek J, Veselovská L, Sýkorová V, Čížek K, Pohl R, Eyer L, Svoboda P, Růžek D, Weber J, Nencka R, Bouřa E, Hocek M. Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses. Acs Infectious Diseases. PMID 33395259 DOI: 10.1021/acsinfecdis.0c00829 |
0.15 |
|
| 2021 |
Terrier O, Dilly S, Pizzorno A, Chalupska D, Humpolickova J, Bouřa E, Berenbaum F, Quideau S, Lina B, Fève B, Adnet F, Sabbah M, Rosa-Calatrava M, Maréchal V, Henri J, et al. Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus. Molecules (Basel, Switzerland). 26. PMID 33946802 DOI: 10.3390/molecules26092593 |
0.148 |
|
| 2022 |
Konkolova E, Krejčová K, Eyer L, Hodek J, Zgarbová M, Fořtová A, Jirasek M, Teply F, Reyes-Gutierrez PE, Růžek D, Weber J, Boura E. A Helquat-like Compound as a Potent Inhibitor of Flaviviral and Coronaviral Polymerases. Molecules (Basel, Switzerland). 27. PMID 35335258 DOI: 10.3390/molecules27061894 |
0.146 |
|
| 2022 |
Holoubek J, Bednářová K, Haviernik J, Huvarová I, Dvořáková Z, Černý J, Outlá M, Salát J, Konkol'ová E, Boura E, Růžek D, Vorlíčková M, Eyer L, Renčiuk D. Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology. Nucleic Acids Research. PMID 35420134 DOI: 10.1093/nar/gkac225 |
0.143 |
|
| 2021 |
Benoni R, Krafcikova P, Baranowski MR, Kowalska J, Boura E, Cahová H. Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase. Viruses. 13. PMID 34578302 DOI: 10.3390/v13091722 |
0.142 |
|
| 2021 |
Cihlova B, Huskova A, Böserle J, Nencka R, Boura E, Silhan J. High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses. Molecules (Basel, Switzerland). 26. PMID 34206406 DOI: 10.3390/molecules26133792 |
0.131 |
|
| 2005 |
Boura E, Liebl D, Spísek R, Fric J, Marek M, Stokrová J, Holán V, Forstová J. Polyomavirus EGFP-pseudocapsids: analysis of model particles for introduction of proteins and peptides into mammalian cells. Febs Letters. 579: 6549-58. PMID 16298367 DOI: 10.1016/J.Febslet.2005.10.062 |
0.131 |
|
| 2021 |
Selvaraj C, Dinesh DC, Krafcikova P, Boura E, Aarthy M, Pravin MA, Singh SK. Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics. Current Molecular Pharmacology. PMID 34488601 DOI: 10.2174/1874467214666210906125959 |
0.13 |
|
| 2023 |
Dejmek M, Brazdova A, Otava T, Polidarova MP, Klíma M, Smola M, Vavrina Z, Buděšínský M, Dračínský M, Liboska R, Boura E, Birkuš G, Nencka R. Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy. European Journal of Medicinal Chemistry. 259: 115685. PMID 37567057 DOI: 10.1016/j.ejmech.2023.115685 |
0.122 |
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| 2023 |
Zgarbová M, Otava T, Silhan J, Nencka R, Weber J, Boura E. Inhibitors of mpox VP39 2'-O methyltransferase efficiently inhibit the monkeypox virus. Antiviral Research. 218: 105714. PMID 37689311 DOI: 10.1016/j.antiviral.2023.105714 |
0.12 |
|
| 2023 |
Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E, Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. Development of Potent and Highly Selective Epoxyketone-based Plasmodium Proteasome Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36617500 DOI: 10.1002/chem.202203958 |
0.119 |
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| 2023 |
Fajtova P, Hurysz BM, Miyamoto Y, Serafim M, Jiang Z, Trujillo DF, Liu L, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, Kirk CJ, Boura E, Eckmann L, et al. Development of subunit selective substrates for proteasome. Biorxiv : the Preprint Server For Biology. PMID 37066163 DOI: 10.1101/2023.04.05.535794 |
0.114 |
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| 2021 |
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, ... ... Boura E, et al. PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation. Science (New York, N.Y.). 374: eabk0410. PMID 34882480 DOI: 10.1126/science.abk0410 |
0.111 |
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| 2021 |
Pimková Polidarová M, Břehová P, Kaiser MM, Smola M, Dračínský M, Smith J, Marek A, Dejmek M, Šála M, Gutten O, Rulíšek L, Novotná B, Brázdová A, Janeba Z, Nencka R, ... Boura E, et al. Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP). Journal of Medicinal Chemistry. PMID 34019405 DOI: 10.1021/acs.jmedchem.1c00301 |
0.105 |
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| 2021 |
Sikdar A, Gupta R, Boura E. Reviewing Antiviral Research Against Viruses Causing Human Diseases - A Structure Guided Approach. Current Molecular Pharmacology. PMID 34348638 DOI: 10.2174/1874467214666210804152836 |
0.105 |
|
| 2022 |
Huskova A, Landova B, Boura E, Silhan J. The rate of formation and stability of abasic site interstrand crosslinks in the DNA duplex. Dna Repair. 113: 103300. PMID 35255312 DOI: 10.1016/j.dnarep.2022.103300 |
0.094 |
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| 2023 |
Kortus S, Rehakova K, Klima M, Kolcheva M, Ladislav M, Langore E, Barackova P, Netolicky J, Misiachna A, Hemelikova K, Humpolickova J, Chalupska D, Silhan J, Kaniakova M, Hrcka Krausova B, ... Boura E, et al. Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 43: 4755-4774. PMID 37286354 DOI: 10.1523/JNEUROSCI.2014-22.2023 |
0.084 |
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