Evzen Boura - Publications

Affiliations: 
Institute of Organic Chemistry and Biochemistry 
Area:
Structural Biology

18/65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Klima M, Tóth DJ, Hexnerova R, Baumlova A, Chalupska D, Tykvart J, Rezabkova L, Sengupta N, Man P, Dubankova A, Humpolickova J, Nencka R, Veverka V, Balla T, Boura E. Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein Scientific Reports. 6. DOI: 10.1038/srep23641  0.68
2015 Mejdrová I, Chalupská D, Kögler M, Šála M, Pla?ková P, Baumlová A, H?ebabecký H, Procházková E, Dejmek M, Guillon R, Strunin D, Weber J, Lee G, Birkus G, Mertlíková-Kaiserová H, ... Boura E, et al. Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. Journal of Medicinal Chemistry. 58: 3767-93. PMID 25897704 DOI: 10.1021/Acs.Jmedchem.5B00499  0.68
2014 Baumlova A, Chalupska D, Ró?ycki B, Jovic M, Wisniewski E, Klima M, Dubankova A, Kloer DP, Nencka R, Balla T, Boura E. The crystal structure of the phosphatidylinositol 4-kinase IIα. Embo Reports. 15: 1085-92. PMID 25168678 DOI: 10.15252/Embr.201438841  0.68
2014 Jovi? M, Kean MJ, Dubankova A, Boura E, Gingras AC, Brill JA, Balla T. Endosomal sorting of VAMP3 is regulated by PI4K2A. Journal of Cell Science. 127: 3745-56. PMID 25002402 DOI: 10.1242/Jcs.148809  0.68
2013 Nemecek D, Boura E, Wu W, Cheng N, Plevka P, Qiao J, Mindich L, Heymann JB, Hurley JH, Steven AC. Subunit folds and maturation pathway of a dsRNA virus capsid. Structure (London, England : 1993). 21: 1374-83. PMID 23891288 DOI: 10.1016/J.Str.2013.06.007  0.68
2012 Różycki B, Boura E, Hurley JH, Hummer G. Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes. Plos Computational Biology. 8: e1002736. PMID 23093927 DOI: 10.1371/Journal.Pcbi.1002736  0.68
2012 Boura E, Ivanov V, Carlson LA, Mizuuchi K, Hurley JH. Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers. The Journal of Biological Chemistry. 287: 28144-51. PMID 22718754 DOI: 10.1074/Jbc.M112.378646  0.68
2012 Baskaran S, Ragusa MJ, Boura E, Hurley JH. Two-site recognition of phosphatidylinositol 3-phosphate by PROPPINs in autophagy. Molecular Cell. 47: 339-48. PMID 22704557 DOI: 10.1016/J.Molcel.2012.05.027  0.68
2012 Boura E, Różycki B, Chung HS, Herrick DZ, Canagarajah B, Cafiso DS, Eaton WA, Hummer G, Hurley JH. Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (London, England : 1993). 20: 874-86. PMID 22579254 DOI: 10.1016/J.Str.2012.03.008  0.68
2012 Noinaj N, Easley NC, Oke M, Mizuno N, Gumbart J, Boura E, Steere AN, Zak O, Aisen P, Tajkhorshid E, Evans RW, Gorringe AR, Mason AB, Steven AC, Buchanan SK. Structural basis for iron piracy by pathogenic Neisseria. Nature. 483: 53-8. PMID 22327295 DOI: 10.1038/Nature10823  0.68
2012 Boura E, Hurley JH. Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit. Proceedings of the National Academy of Sciences of the United States of America. 109: 1901-6. PMID 22232651 DOI: 10.1073/Pnas.1117597109  0.68
2011 Boura E, Rózycki B, Herrick DZ, Chung HS, Vecer J, Eaton WA, Cafiso DS, Hummer G, Hurley JH. Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 9437-42. PMID 21596998 DOI: 10.1073/Pnas.1101763108  0.68
2010 Hurley JH, Boura E, Carlson LA, Różycki B. Membrane budding. Cell. 143: 875-87. PMID 21145455 DOI: 10.1016/j.cell.2010.11.030  0.68
2010 Rezabkova L, Boura E, Herman P, Vecer J, Bourova L, Sulc M, Svoboda P, Obsilova V, Obsil T. 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3). Journal of Structural Biology. 170: 451-61. PMID 20347994 DOI: 10.1016/J.Jsb.2010.03.009  0.68
2009 Im YJ, Wollert T, Boura E, Hurley JH. Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. Developmental Cell. 17: 234-43. PMID 19686684 DOI: 10.1016/J.Devcel.2009.07.008  0.68
2008 Obsilova V, Nedbalkova E, Silhan J, Boura E, Herman P, Vecer J, Sulc M, Teisinger J, Dyda F, Obsil T. The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase Biochemistry. 47: 1768-1777. PMID 18181650 DOI: 10.1021/Bi7019468  0.68
2007 Boura E, Silhan J, Herman P, Vecer J, Sulc M, Teisinger J, Obsilova V, Obsil T. Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding Journal of Biological Chemistry. 282: 8265-8275. PMID 17244620 DOI: 10.1074/Jbc.M605682200  0.68
2005 Obsilova V, Vecer J, Herman P, Pabianova A, Sulc M, Teisinger J, Boura E, Obsil T. 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4 Biochemistry. 44: 11608-11617. PMID 16114898 DOI: 10.1021/Bi050618R  0.68
Low-probability matches
2019 Chalupska D, RóŻycki B, Klima M, Boura E. Structural insights into ACBD3 hijacking by picornaviruses. Protein Science : a Publication of the Protein Society. PMID 31583778 DOI: 10.1002/Pro.3738  0.12
2017 Klima M, Chalupska D, Różycki B, Humpolickova J, Rezabkova L, Silhan J, Baumlova A, Dubankova A, Boura E. Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein. Structure (London, England : 1993). 25: 219-230. PMID 28065508 DOI: 10.1016/J.Str.2016.11.021  0.04
2021 Rulíšek L, Smola M, Gutten O, Dejmek M, Kožíšek M, Evangelidis T, Tehrani ZA, Novotná B, Nencka R, Birkuš G, Boura E. Ligand Strain and Its Conformational Complexity Is a Major Factor Determining Binding of Cyclic Dinucleotides to STING Protein. Angewandte Chemie (International Ed. in English). PMID 33616279 DOI: 10.1002/anie.202016805  0.01
2021 Vavřina Z, Gutten O, Smola M, Zavřel M, Aliakbar Tehrani Z, Charvát V, Kožíšek M, Boura E, Birkuš G, Rulíšek L. Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory. Biochemistry. PMID 33586948 DOI: 10.1021/acs.biochem.0c00949  0.01
2020 Selvaraj C, Panwar U, Dinesh DC, Boura E, Singh P, Dubey VK, Singh SK. Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease. Frontiers in Chemistry. 8: 595273. PMID 33585398 DOI: 10.3389/fchem.2020.595273  0.01
2020 Selvaraj C, Dinesh DC, Panwar U, Boura E, Singh SK. High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 33306471 DOI: 10.1109/TCBB.2020.3037136  0.01
2020 Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R, Veverka V, Boura E. Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein. Plos Pathogens. 16: e1009100. PMID 33264373 DOI: 10.1371/journal.ppat.1009100  0.01
2020 Konkolova E, Dejmek M, Hřebabecký H, Šála M, Böserle J, Nencka R, Boura E. Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses. Antiviral Research. 182: 104899. PMID 32763313 DOI: 10.1016/J.Antiviral.2020.104899  0.01
2020 Krafcikova P, Silhan J, Nencka R, Boura E. Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin. Nature Communications. 11: 3717. PMID 32709887 DOI: 10.1038/S41467-020-17495-9  0.01
2020 Selvaraj C, Dinesh DC, Panwar U, Abhirami R, Boura E, Singh SK. Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19. Journal of Biomolecular Structure & Dynamics. 1-12. PMID 32567979 DOI: 10.1080/07391102.2020.1778535  0.01
2020 Konkolova E, Klima M, Nencka R, Boura E. Structural analysis of the putative SARS-CoV-2 primase complex. Journal of Structural Biology. 107548. PMID 32535228 DOI: 10.1016/J.Jsb.2020.107548  0.01
2020 Pemberton JG, Kim YJ, Humpolickova J, Eisenreichova A, Sengupta N, Toth DJ, Boura E, Balla T. Defining the subcellular distribution and metabolic channeling of phosphatidylinositol. The Journal of Cell Biology. 219. PMID 32211894 DOI: 10.1083/Jcb.201906130  0.01
2019 Smola M, Horova V, Boura E, Klima M. Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses. Archives of Virology. PMID 31845156 DOI: 10.1007/S00705-019-04490-9  0.01
2019 Dinesh DC, Tamilarasan S, Rajaram K, Bouřa E. Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases. Current Drug Targets. PMID 31538891 DOI: 10.2174/1389450119666190920153247  0.01
2019 Smola M, Birkus G, Boura E. No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides. Acta Crystallographica. Section F, Structural Biology Communications. 75: 593-598. PMID 31475926 DOI: 10.1107/S2053230X19010999  0.01
2019 Dubankova A, Horova V, Klima M, Boura E. Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. Journal of Structural Biology. PMID 31415898 DOI: 10.1016/J.Jsb.2019.08.004  0.01
2019 Horova V, Lyoo H, Różycki B, Chalupska D, Smola M, Humpolickova J, Strating JRPM, van Kuppeveld FJM, Boura E, Klima M. Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites. Plos Pathogens. 15: e1007962. PMID 31381608 DOI: 10.1371/Journal.Ppat.1007962  0.01
2019 Dubankova A, Boura E. Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses. Antiviral Research. 169: 104536. PMID 31202975 DOI: 10.1016/J.Antiviral.2019.104536  0.01
2019 Chalupska D, Różycki B, Humpolickova J, Faltova L, Klima M, Boura E. Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins. Scientific Reports. 9: 567. PMID 30679637 DOI: 10.1038/S41598-018-37158-6  0.01
2019 Sengupta N, Jović M, Barnaeva E, Kim DW, Hu X, Southall N, Dejmek M, Mejdrova I, Nencka R, Baumlova A, Chalupska D, Boura E, Ferrer M, Marugan J, Balla T. A large scale high throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha. Journal of Lipid Research. PMID 30626625 DOI: 10.1194/Jlr.D090159  0.01
2018 Silhan J, Zhao Q, Boura E, Thomson H, Förster A, Tang CM, Freemont PS, Baldwin GS. Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. Nucleic Acids Research. PMID 30329088 DOI: 10.2210/Pdb6Fke/Pdb  0.01
2018 Šebera J, Dubankova A, Sychrovský V, Ruzek D, Boura E, Nencka R. The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors. Scientific Reports. 8: 11132. PMID 30042483 DOI: 10.1038/S41598-018-29459-7  0.01
2018 Sohn M, Korzeniowski M, Zewe JP, Wills RC, Hammond GRV, Humpolickova J, Vrzal L, Chalupska D, Veverka V, Fairn GD, Boura E, Balla T. PI(4,5)Pcontrols plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. The Journal of Cell Biology. PMID 29472386 DOI: 10.1083/Jcb.201710095  0.01
2018 Peti W, Page R, Boura E, Różycki B. Structures of Dynamic Protein Complexes: Hybrid Techniques to Study MAP Kinase Complexes and the ESCRT System. Methods in Molecular Biology (Clifton, N.J.). 1688: 375-389. PMID 29151218 DOI: 10.1007/978-1-4939-7386-6_17  0.01
2017 Dubankova A, Humpolickova J, Klima M, Boura E. Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D . Scientific Reports. 7: 17309. PMID 29230036 DOI: 10.1038/S41598-017-17621-6  0.01
2017 Chalupska D, Eisenreichova A, Różycki B, Rezabkova L, Humpolickova J, Klima M, Boura E. Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro. Journal of Structural Biology. 200: 36-44. PMID 28864297 DOI: 10.1016/J.Jsb.2017.08.006  0.01
2017 Hercik K, Brynda J, Nencka R, Boura E. Structural basis of Zika virus methyltransferase inhibition by sinefungin. Archives of Virology. 162: 2091-2096. PMID 28357511 DOI: 10.1007/S00705-017-3345-X  0.01
2017 Boura E, Baumlova A, Chalupska D, Dubankova A, Klima M. Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography. Protein Science : a Publication of the Protein Society. 26: 1116-1123. PMID 28342173 DOI: 10.1002/Pro.3162  0.01
2017 Humpolickova J, Mejdrová I, Matousova M, Nencka R, Boura E. Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB). Journal of Medicinal Chemistry. 60: 119-127. PMID 28004946 DOI: 10.1021/Acs.Jmedchem.6B01466  0.01
2017 Hercík K, Kozak J, Šála M, Dejmek M, Hřebabecký H, Zborníková E, Smola M, Ruzek D, Nencka R, Boura E. Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase. Antiviral Research. 137: 131-133. PMID 27902932 DOI: 10.1016/J.Antiviral.2016.11.020  0.01
2016 Boura E, Nencka R. Corrigendum to: ''Phosphatidylinositol 4-kinases: Function, structure, and inhibition'' [Exp. Cell Res. 337/2 (2015) 136-145]. Experimental Cell Research. 341: 110. PMID 33096590 DOI: 10.1016/j.yexcr.2015.11.018  0.01
2016 Mejdrová I, Chalupská D, Plačková P, Müller C, Šála M, Klíma M, Baumlová A, Hřebabecký H, Procházková E, Dejmek M, Strunin D, Weber J, Lee G, Matoušová M, Mertlíková-Kaiserová H, ... ... Boura E, et al. Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. Journal of Medicinal Chemistry. PMID 28004945 DOI: 10.1021/Acs.Jmedchem.6B01465  0.01
2016 Eisenreichova A, Klima M, Boura E. Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation. Acta Crystallographica. Section F, Structural Biology Communications. 72: 799-803. PMID 27827352 DOI: 10.1107/S2053230X16015053  0.01
2016 Baumlova A, Gregor J, Boura E. The structural basis for calcium inhibition of lipid kinase PI4K IIalpha and comparison with the apo state. Physiological Research. 65: 987-993. PMID 27539108 DOI: 10.33549/PHYSIOLRES.933344  0.01
2016 Klima M, Tóth DJ, Hexnerova R, Baumlova A, Chalupska D, Tykvart J, Rezabkova L, Sengupta N, Man P, Dubankova A, Humpolickova J, Nencka R, Veverka V, Balla T, Boura E. Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein. Scientific Reports. 6: 23641. PMID 27009356 DOI: 10.1038/Srep23641  0.01
2016 Boura E, Nencka R. Corrigendum to: ‘‘Phosphatidylinositol 4-kinases: Function, structure, and inhibition’’ [Exp. Cell Res. 337/2 (2015) 136–145] Experimental Cell Research. 341: 110. DOI: 10.1016/J.Yexcr.2015.11.018  0.01
2015 Boura E, Nencka R. Phosphatidylinositol 4-kinases: Function, structure, and inhibition. Experimental Cell Research. 337: 136-45. PMID 26183104 DOI: 10.1016/J.Yexcr.2015.03.028  0.01
2015 Klima M, Baumlova A, Chalupska D, Hřebabecký H, Dejmek M, Nencka R, Boura E. The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design. Acta Crystallographica. Section D, Biological Crystallography. 71: 1555-63. PMID 26143926 DOI: 10.1107/S1399004715009505  0.01
2015 Dejmek M, Šála M, Hřebabecký H, Dračínský M, Procházková E, Chalupská D, Klíma M, Plačková P, Hájek M, Andrei G, Naesens L, Leyssen P, Neyts J, Balzarini J, Boura E, et al. Norbornane-based nucleoside and nucleotide analogues locked in North conformation. Bioorganic & Medicinal Chemistry. 23: 184-91. PMID 25435471 DOI: 10.1016/J.Bmc.2014.11.011  0.01
2014 Różycki B, Boura E. Large, dynamic, multi-protein complexes: a challenge for structural biology. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 26: 463103. PMID 25335513 DOI: 10.1088/0953-8984/26/46/463103  0.01
2013 Nemecek D, Plevka P, Boura E. Using cryoEM reconstruction and phase extension to determine crystal structure of bacteriophage ϕ6 major capsid protein. The Protein Journal. 32: 635-40. PMID 24293129 DOI: 10.1007/S10930-013-9526-X  0.01
2011 Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J. Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner. Cancer Research. 71: 946-54. PMID 21245099 DOI: 10.1158/0008-5472.Can-10-2203  0.01
2010 Boura E, Rezabkova L, Brynda J, Obsilova V, Obsil T. Structure of the human FOXO4-DBD-DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA. Acta Crystallographica. Section D, Biological Crystallography. 66: 1351-7. PMID 21123876 DOI: 10.1107/S0907444910042228  0.01
2010 Huerfano S, Zíla V, Boura E, Spanielová H, Stokrová J, Forstová J. Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection. The Febs Journal. 277: 1270-83. PMID 20121946 DOI: 10.1111/J.1742-4658.2010.07558.X  0.01
2005 Boura E, Liebl D, Spísek R, Fric J, Marek M, Stokrová J, Holán V, Forstová J. Polyomavirus EGFP-pseudocapsids: analysis of model particles for introduction of proteins and peptides into mammalian cells. Febs Letters. 579: 6549-58. PMID 16298367 DOI: 10.1016/J.Febslet.2005.10.062  0.01
2019 Novotná B, Vaneková L, Zavřel M, Buděšínský M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Pimková Polidarová M, Brázdová A, Liboska R, Štěpánek I, Vavrina Z, Jandušík T, Nencka R, et al. Enzymatic Preparation of 2'-5', 3'-5'Cyclic Dinucleotides, Their Binding Properties to STING Adaptor Protein, and Structure/Activity Correlations. Journal of Medicinal Chemistry. PMID 31715099 DOI: 10.1021/Acs.Jmedchem.9B01062  0
2019 Novotna B, Vanekova L, Zavrel M, Budesinsky M, Dejmek M, Smola M, Gutten O, Tehrani ZA, Polidarova MP, Brazdova A, Liboska R, Stepanek I, Vavrina Z, Jandusik T, Nencka R, ... ... Boura E, et al. Enzymatic Preparation of 2'-5', 3'-5'Cyclic Dinucleotides, Their Binding Properties to STING Adaptor Protein, and Structure/Activity Correlations. Journal of Medicinal Chemistry. DOI: 10.2210/Pdb6S27/Pdb  0
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