| Year |
Citation |
Score |
| 2017 |
Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, ... Eaton DL, et al. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Jci Insight. 2. PMID 29202460 DOI: 10.1172/Jci.Insight.95978 |
0.743 |
|
| 2017 |
Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ. Microphysiological Systems to Assess Nonclinical Toxicity. Current Protocols in Toxicology. 73: 14.18.1-14.18.28. PMID 28777442 DOI: 10.1002/Cptx.27 |
0.761 |
|
| 2017 |
Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL. Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 28089783 DOI: 10.1016/J.Tiv.2017.01.007 |
0.723 |
|
| 2016 |
Chang SY, Weber EJ, Van Ness KP, Eaton DL, Kelly EJ. Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function. Clinical Pharmacology and Therapeutics. PMID 27448090 DOI: 10.1002/Cpt.436 |
0.75 |
|
| 2013 |
Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, et al. Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. Stem Cell Research & Therapy. 4: S17. PMID 24564863 DOI: 10.1186/Scrt378 |
0.705 |
|
| 2013 |
Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL. Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo. Toxicology and Applied Pharmacology. 266: 122-31. PMID 23153560 DOI: 10.1016/J.Taap.2012.10.029 |
0.321 |
|
| 2012 |
Smith WE, Brownell J, White CC, Afsharinejad Z, Tsai J, Hu X, Polyak SJ, Gao X, Kavanagh TJ, Eaton DL. In vitro toxicity assessment of amphiphillic polymer-coated CdSe/ZnS quantum dots in two human liver cell models. Acs Nano. 6: 9475-84. PMID 23039050 DOI: 10.1021/Nn302288R |
0.316 |
|
| 2012 |
Gross-Steinmeyer K, Eaton DL. Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1). Toxicology. 299: 69-79. PMID 22640941 DOI: 10.1016/j.tox.2012.05.016 |
0.374 |
|
| 2007 |
Zhou C, Poulton EJ, Grün F, Bammler TK, Blumberg B, Thummel KE, Eaton DL. The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Molecular Pharmacology. 71: 220-9. PMID 17028159 DOI: 10.1124/Mol.106.029264 |
0.369 |
|
| 2005 |
Gross-Steinmeyer K, Stapleton PL, Tracy JH, Bammler TK, Lehman T, Strom SC, Eaton DL. Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 35: 419-38. PMID 16012075 DOI: 10.1080/00498250500137427 |
0.357 |
|
| 2005 |
Gross-Steinmeyer K, Stapleton PL, Liu F, Tracy JH, Bammler TK, Quigley SD, Farin FM, Buhler DR, Safe SH, Strom SC, Eaton DL. Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 619-32. PMID 15672752 DOI: 10.1080/00498250412331285481 |
0.342 |
|
| 2004 |
Abel EL, Opp SM, Verlinde CL, Bammler TK, Eaton DL. Characterization of atrazine biotransformation by human and murine glutathione S-transferases. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 230-8. PMID 15115887 DOI: 10.1093/Toxsci/Kfh152 |
0.311 |
|
| 2004 |
Abel EL, Bammler TK, Eaton DL. Biotransformation of methyl parathion by glutathione S-transferases. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 224-32. PMID 15103050 DOI: 10.1093/toxsci/kfh118 |
0.31 |
|
| 2002 |
Kelly EJ, Erickson KE, Sengstag C, Eaton DL. Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 35-42. PMID 11752683 DOI: 10.1093/Toxsci/65.1.35 |
0.603 |
|
| 2001 |
Eaton DL, Bammler TK, Kelly EJ. Interindividual differences in response to chemoprotection against aflatoxin-induced hepatocarcinogenesis: Implications for human biotransformation enzyme polymorphisms Advances in Experimental Medicine and Biology. 500: 559-576. PMID 11764998 DOI: 10.1007/978-1-4615-0667-6_85 |
0.63 |
|
| 2001 |
Cheesman MJ, Kneller MB, Kelly EJ, Thompson SJ, Yeung CK, Eaton DL, Rettie AE. Purification and characterization of hexahistidine-tagged cyclohexanone monooxygenase expressed in Saccharomyces cerevisiae and Escherichia coli. Protein Expression and Purification. 21: 81-6. PMID 11162390 DOI: 10.1006/Prep.2000.1340 |
0.508 |
|
| 2000 |
Wang C, Bammler TK, Guo Y, Kelly EJ, Eaton DL. Mu-Class GSTs are responsible for aflatoxin B1-8,9-epoxide-conjugating activity in the nonhuman primate Macaca fascicularis liver Toxicological Sciences. 56: 26-36. PMID 10869451 DOI: 10.1093/Toxsci/56.1.26 |
0.567 |
|
| 1998 |
Tonge RP, Kelly EJ, Bruschi SA, Kalhorn T, Eaton DL, Nebert DW, Nelson SD. Role of CYP1A2 in the hepatotoxicity of acetaminophen: Investigations using Cyp1a2 null mice Toxicology and Applied Pharmacology. 153: 102-108. PMID 9875304 DOI: 10.1006/Taap.1998.8543 |
0.561 |
|
| 1998 |
Neal GE, Eaton DL, Judah DJ, Verma A. Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro systems. Toxicology and Applied Pharmacology. 151: 152-8. PMID 9705898 DOI: 10.1006/TAAP.1998.8440 |
0.395 |
|
| 1997 |
Gallagher EP, Kunze KL, Stapleton PL, Eaton DL. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4. Toxicology and Applied Pharmacology. 141: 595-606. PMID 8975785 DOI: 10.1006/Taap.1996.0326 |
0.38 |
|
| 1996 |
Heinonen JT, Fisher R, Brendel K, Eaton DL. Determination of aflatoxin B1 biotransformation and binding to hepatic macromolecules in human precision liver slices. Toxicology and Applied Pharmacology. 136: 1-7. PMID 8560461 DOI: 10.1006/TAAP.1996.0001 |
0.374 |
|
| 1995 |
Slone DH, Gallagher EP, Ramsdell HS, Rettie AE, Stapleton PL, Berlad LG, Eaton DL. Human variability in hepatic glutathione S-transferase-mediated conjugation of aflatoxin B1-epoxide and other substrates. Pharmacogenetics. 5: 224-33. PMID 8528269 DOI: 10.1097/00008571-199508000-00006 |
0.366 |
|
| 1994 |
Eaton DL, Gallagher EP. Mechanisms of aflatoxin carcinogenesis. Annual Review of Pharmacology and Toxicology. 34: 135-72. PMID 8042848 DOI: 10.1146/ANNUREV.PA.34.040194.001031 |
0.304 |
|
| 1993 |
Davis MA, Wallig MA, Eaton D, Borroz KI, Jeffery EH. Differential effect of cyanohydroxybutene on glutathione synthesis in liver and pancreas of male rats Toxicology and Applied Pharmacology. 123: 257-264. PMID 7902618 DOI: 10.1006/Taap.1993.1244 |
0.383 |
|
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