Year |
Citation |
Score |
2013 |
Pöther DC, Gierok P, Harms M, Mostertz J, Hochgräfe F, Antelmann H, Hamilton CJ, Borovok I, Lalk M, Aharonowitz Y, Hecker M. Distribution and infection-related functions of bacillithiol in Staphylococcus aureus. International Journal of Medical Microbiology : Ijmm. 303: 114-23. PMID 23517692 DOI: 10.1016/J.Ijmm.2013.01.003 |
0.357 |
|
2011 |
Seifart Gomes C, Izar B, Pazan F, Mohamed W, Mraheil MA, Mukherjee K, Billion A, Aharonowitz Y, Chakraborty T, Hain T. Universal stress proteins are important for oxidative and acid stress resistance and growth of Listeria monocytogenes EGD-e in vitro and in vivo. Plos One. 6: e24965. PMID 21980369 DOI: 10.1371/Journal.Pone.0024965 |
0.337 |
|
2011 |
Ofer A, Kreft J, Logan DT, Cohen G, Borovok I, Aharonowitz Y. Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain. Journal of Bacteriology. 193: 2931-40. PMID 21478338 DOI: 10.1128/Jb.01405-10 |
0.368 |
|
2010 |
Rabinovitch I, Yanku M, Yeheskel A, Cohen G, Borovok I, Aharonowitz Y. Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase. Journal of Bacteriology. 192: 4963-72. PMID 20675493 DOI: 10.1128/Jb.00539-10 |
0.432 |
|
2009 |
Pöther DC, Liebeke M, Hochgräfe F, Antelmann H, Becher D, Lalk M, Lindequist U, Borovok I, Cohen G, Aharonowitz Y, Hecker M. Diamide triggers mainly S thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus Journal of Bacteriology. 191: 7520-7530. PMID 19837798 DOI: 10.1128/Jb.00937-09 |
0.397 |
|
2009 |
Malki L, Yanku M, Borovok I, Cohen G, Mevarech M, Aharonowitz Y. Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii. Journal of Bacteriology. 191: 5196-204. PMID 19525351 DOI: 10.1128/Jb.00297-09 |
0.384 |
|
2009 |
Grinberg I, Shteinberg T, Hassan AQ, Aharonowitz Y, Borovok I, Cohen G. Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: role in nucleotide binding, oligomerization, and DNA interactions. Journal of Bacteriology. 191: 1169-79. PMID 19047342 DOI: 10.1128/Jb.01145-08 |
0.336 |
|
2007 |
Makhlin J, Kofman T, Borovok I, Kohler C, Engelmann S, Cohen G, Aharonowitz Y. Staphylococcus aureus ArcR controls expression of the arginine deiminase operon Journal of Bacteriology. 189: 5976-5986. PMID 17557828 DOI: 10.1128/Jb.00592-07 |
0.43 |
|
2007 |
Torrents E, Grinberg I, Gorovitz-Harris B, Lundström H, Borovok I, Aharonowitz Y, Sjöberg BM, Cohen G. NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. Journal of Bacteriology. 189: 5012-21. PMID 17496099 DOI: 10.1128/Jb.00440-07 |
0.386 |
|
2006 |
Grinberg I, Shteinberg T, Gorovitz B, Aharonowitz Y, Cohen G, Borovok I. The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons. Journal of Bacteriology. 188: 7635-44. PMID 16950922 DOI: 10.1128/Jb.00903-06 |
0.378 |
|
2006 |
Borovok I, Gorovitz B, Schreiber R, Aharonowitz Y, Cohen G. Coenzyme B12 controls transcription of the Streptomyces class Ia ribonucleotide reductase nrdABS operon via a riboswitch mechanism. Journal of Bacteriology. 188: 2512-20. PMID 16547038 DOI: 10.1128/Jb.188.7.2512-2520.2006 |
0.34 |
|
2005 |
Gopal S, Borovok I, Ofer A, Yanku M, Cohen G, Goebel W, Kreft J, Aharonowitz Y. A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis. Journal of Bacteriology. 187: 3839-47. PMID 15901709 DOI: 10.1128/Jb.187.11.3839-3847.2005 |
0.448 |
|
2004 |
Borovok I, Gorovitz B, Yanku M, Schreiber R, Gust B, Chater K, Aharonowitz Y, Cohen G. Alternative oxygen-dependent and oxygen-independent ribonucleotide reductases in Streptomyces: cross-regulation and physiological role in response to oxygen limitation. Molecular Microbiology. 54: 1022-35. PMID 15522084 DOI: 10.1111/J.1365-2958.2004.04325.X |
0.386 |
|
2004 |
Lithgow JK, Hayhurst EJ, Cohen G, Aharonowitz Y, Foster SJ. Role of a cysteine synthase in Staphylococcus aureus. Journal of Bacteriology. 186: 1579-90. PMID 14996787 DOI: 10.1128/Jb.186.6.1579-1590.2004 |
0.403 |
|
2004 |
Uziel O, Borovok I, Schreiber R, Cohen G, Aharonowitz Y. Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress. Journal of Bacteriology. 186: 326-34. PMID 14702300 DOI: 10.1128/Jb.186.2.326-334.2004 |
0.369 |
|
2002 |
Borovok I, Kreisberg-Zakarin R, Yanko M, Schreiber R, Myslovati M, Aslund F, Holmgren A, Cohen G, Aharonowitz Y. Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth. Microbiology (Reading, England). 148: 391-404. PMID 11832503 DOI: 10.1099/00221287-148-2-391 |
0.388 |
|
2001 |
Paget MSB, Molle V, Cohen G, Aharonowitz Y, Buttner MJ. Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon. Molecular Microbiology. 42: 1007-1020. PMID 11737643 DOI: 10.1046/J.1365-2958.2001.02675.X |
0.386 |
|
2001 |
Masalha M, Borovok I, Schreiber R, Aharonowitz Y, Cohen G. Analysis of Transcription of the Staphylococcus aureus Aerobic Class Ib and Anaerobic Class III Ribonucleotide Reductase Genes in Response to Oxygen Journal of Bacteriology. 183: 7260-7272. PMID 11717286 DOI: 10.1128/Jb.183.24.7260-7272.2001 |
0.355 |
|
2000 |
Kreisberg-Zakarin R, Borovok I, Yanko M, Frolow F, Aharonowitz Y, Cohen G. Structure-function studies of the non-heme iron active site of isopenicillin N synthase: some implications for catalysis. Biophysical Chemistry. 86: 109-118. PMID 11026676 DOI: 10.1016/S0301-4622(00)00123-X |
0.331 |
|
1999 |
Kreisberg-Zakarin R, Borovok I, Yanko M, Aharonowitz Y, Cohen G. Recent advances in the structure and function of isopenicillin N synthase. Antonie Van Leeuwenhoek. 75: 33-9. PMID 10422580 DOI: 10.1023/A:1001723202234 |
0.344 |
|
1998 |
Gal-Mor O, Borovok I, Av-Gay Y, Cohen G, Aharonowitz Y. Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria Gene. 217: 83-90. PMID 9795152 DOI: 10.1016/S0378-1119(98)00357-6 |
0.588 |
|
1997 |
Ben-Menachem G, Himmelreich R, Herrmann R, Aharonowitz Y, Rottem S. The thioredoxin reductase system of mycoplasmas. Microbiology (Reading, England). 143: 1933-1940. PMID 9202470 DOI: 10.1099/00221287-143-6-1933 |
0.302 |
|
1997 |
Landman O, Borovok I, Aharonowitz Y, Cohen G. The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis Febs Letters. 405: 172-174. PMID 9089285 DOI: 10.1016/S0014-5793(97)00180-4 |
0.32 |
|
1996 |
Borovok I, Landman O, Kreisberg-Zakarin R, Aharonowitz Y, Cohen G. Ferrous Active Site of Isopenicillin N Synthase: Genetic and Sequence Analysis of the Endogenous Ligands† Biochemistry. 35: 1981-1987. PMID 8639682 DOI: 10.1021/Bi951534T |
0.387 |
|
1996 |
Newton GL, Arnold K, Price MS, Sherrill C, Delcardayre SB, Aharonowitz Y, Cohen G, Davies J, Fahey RC, Davis C. Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. Journal of Bacteriology. 178: 1990-5. PMID 8606174 DOI: 10.1128/Jb.178.7.1990-1995.1996 |
0.51 |
|
1995 |
Newton GL, Bewley CA, Dwyer TJ, Horn R, Aharonowitz Y, Cohen G, Davies J, Faulkner DJ, Fahey RC. The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol. European Journal of Biochemistry / Febs. 230: 821-5. PMID 7607257 DOI: 10.1111/J.1432-1033.1995.0821H.X |
0.499 |
|
1994 |
Cohen G, Argaman A, Schreiber R, Mislovati M, Aharonowitz Y. The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis. Journal of Bacteriology. 176: 973-984. PMID 8106340 DOI: 10.1128/Jb.176.4.973-984.1994 |
0.462 |
|
1993 |
Newton GL, Fahey RC, Cohen G, Aharonowitz Y. Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants. Journal of Bacteriology. 175: 2734-42. PMID 8478335 DOI: 10.1128/Jb.175.9.2734-2742.1993 |
0.36 |
|
1993 |
Aharonowitz Y, Av-Gay Y, Schreiber R, Cohen G. Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in β-lactam antibiotic biosynthesis Journal of Bacteriology. 175: 623-629. PMID 8423136 DOI: 10.1128/Jb.175.3.623-629.1993 |
0.618 |
|
1993 |
Cohen G, Yanko M, Mislovati M, Argaman A, Schreiber R, Av-Gay Y, Aharonowitz Y. Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: Sequences, expression, and organization of the genes Journal of Bacteriology. 175: 5159-5167. PMID 8349555 DOI: 10.1128/Jb.175.16.5159-5167.1993 |
0.635 |
|
1992 |
Schwecke T, Aharonowitz Y, Palissa H, Döhren Hv, Kleinkauf H, Liempt Hv. Enzymatic characterisation of the multifunctional enzyme δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine synthetase from Streptomyces clavuligerus Febs Journal. 205: 687-694. PMID 1572368 DOI: 10.1111/J.1432-1033.1992.Tb16830.X |
0.339 |
|
1992 |
Aharonowitz Y, Cohen G, Martin JF. Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution. Annual Review of Microbiology. 46: 461-495. PMID 1444264 DOI: 10.1146/Annurev.Mi.46.100192.002333 |
0.395 |
|
1992 |
Av-gay Y, Aharonowitz Y, Cohen G. Streptomyces contain a 7.0 KDa cold shock like protein Nucleic Acids Research. 20: 5478. PMID 1437568 DOI: 10.1093/Nar/20.20.5478 |
0.555 |
|
1991 |
Landman O, Shiffman D, Av-Gay Y, Aharonowitz Y, Cohen G. High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies Fems Microbiology Letters. 84: 239-244. PMID 1666621 |
0.59 |
|
1991 |
Landman O, Shiffman D, Av-Gay Y, Aharonowitz Y, Cohen G. High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies Fems Microbiology Letters. 84: 239-244. DOI: 10.1111/J.1574-6968.1991.Tb04603.X |
0.426 |
|
1990 |
Shiffman D, Cohen G, Aharonowitz Y, Palissa H, Dohren Hv, KIeinkauf H, Mevarech M. Nucleotide sequence of the isopenicillin N synthase gene (pcbC) of the gram negative Flavobacterium sp. SC 12,154. Nucleic Acids Research. 18: 660-660. PMID 2308852 DOI: 10.1093/Nar/18.3.660 |
0.362 |
|
1990 |
Landan G, Cohen G, Aharonowitz Y, Shuali Y, Graur D, Shiffman D. Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer. Molecular Biology and Evolution. 7: 399-406. PMID 2263192 DOI: 10.1093/Oxfordjournals.Molbev.A040615 |
0.368 |
|
1990 |
Cohen G, Shiffman D, Mevarech M, Aharonowitz Y. Microbial isopenicillin N synthase genes: structure, function, diversity and evolution. Trends in Biotechnology. 8: 105-111. PMID 1366527 DOI: 10.1016/0167-7799(90)90148-Q |
0.405 |
|
1989 |
Shiffman D, Mevarech M, Jensen SE, Cohen G, Aharonowitz Y. Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces. Molecular & General Genetics : Mgg. 214: 562-9. PMID 3216857 DOI: 10.1007/Bf00330495 |
0.429 |
|
1988 |
Leskiw BK, Aharonowitz Y, Mevarech M, Wolfe S, Vining LC, Westlake DWS, Jensen SE. Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus Gene. 62: 187-196. PMID 3130293 DOI: 10.1016/0378-1119(88)90557-4 |
0.309 |
|
1988 |
Keen CL, Mendelovitz S, Cohen G, Aharonowitz Y, Roy KL. Isolation and characterization of a linear DNA plasmid from Streptomyces clavuligerus. Molecular & General Genetics : Mgg. 212: 172-6. PMID 2836705 DOI: 10.1007/Bf00322461 |
0.342 |
|
1988 |
Granot I, Aharonowitz Y, Freeman A. Cosolvent effect on Δ1-steroid-reductase activity of free and PAAH entrapped Mycobacterium Sp. NRRL B-3805 cells Applied Microbiology and Biotechnology. 27: 457-463. DOI: 10.1007/Bf00451613 |
0.317 |
|
1987 |
Vining LC, Jensen SE, Westlake DWS, Aharonowitz Y, Wolfe S. Cephamycin production and isopenicillin N synthetase activity in cultures of Streptomyces clavuligerus Applied Microbiology and Biotechnology. 27: 240-246. DOI: 10.1007/Bf00252925 |
0.311 |
|
1986 |
Jensen SE, Leskiw BK, Vining LC, Aharonowitz Y, Westlake DW, Wolfe S. Purification of isopenicillin N synthetase from Streptomyces clavuligerus Canadian Journal of Microbiology. 32: 953-958. PMID 3815161 DOI: 10.1139/M86-176 |
0.359 |
|
1983 |
Mendelovitz S, Aharonowitz Y. β-Lactam Antibiotic Production by Streptomyces clavuligerus Mutants Impaired in Regulation of Aspartokinase Microbiology. 129: 2063-2069. PMID 6313854 DOI: 10.1099/00221287-129-7-2063 |
0.324 |
|
1980 |
Aharonowitz Y. Nitrogen Metabolite Regulation of Antibiotic Biosynthesis Annual Review of Microbiology. 34: 209-233. PMID 6108090 DOI: 10.1146/Annurev.Mi.34.100180.001233 |
0.331 |
|
1979 |
Aharonowitz Y, Demain AL. Nitrogen nutrition and regulation of cephalosporin production in Streptomyces clavuligerus. Canadian Journal of Microbiology. 25: 61-7. PMID 427656 DOI: 10.1139/M79-010 |
0.326 |
|
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