Yair Aharonowitz - Publications

Affiliations: 
Microbiology Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Pöther DC, Gierok P, Harms M, Mostertz J, Hochgräfe F, Antelmann H, Hamilton CJ, Borovok I, Lalk M, Aharonowitz Y, Hecker M. Distribution and infection-related functions of bacillithiol in Staphylococcus aureus. International Journal of Medical Microbiology : Ijmm. 303: 114-23. PMID 23517692 DOI: 10.1016/J.Ijmm.2013.01.003  0.357
2011 Seifart Gomes C, Izar B, Pazan F, Mohamed W, Mraheil MA, Mukherjee K, Billion A, Aharonowitz Y, Chakraborty T, Hain T. Universal stress proteins are important for oxidative and acid stress resistance and growth of Listeria monocytogenes EGD-e in vitro and in vivo. Plos One. 6: e24965. PMID 21980369 DOI: 10.1371/Journal.Pone.0024965  0.337
2011 Ofer A, Kreft J, Logan DT, Cohen G, Borovok I, Aharonowitz Y. Implications of the inability of Listeria monocytogenes EGD-e to grow anaerobically due to a deletion in the class III NrdD ribonucleotide reductase for its use as a model laboratory strain. Journal of Bacteriology. 193: 2931-40. PMID 21478338 DOI: 10.1128/Jb.01405-10  0.368
2010 Rabinovitch I, Yanku M, Yeheskel A, Cohen G, Borovok I, Aharonowitz Y. Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase. Journal of Bacteriology. 192: 4963-72. PMID 20675493 DOI: 10.1128/Jb.00539-10  0.432
2009 Pöther DC, Liebeke M, Hochgräfe F, Antelmann H, Becher D, Lalk M, Lindequist U, Borovok I, Cohen G, Aharonowitz Y, Hecker M. Diamide triggers mainly S thiolations in the cytoplasmic proteomes of Bacillus subtilis and Staphylococcus aureus Journal of Bacteriology. 191: 7520-7530. PMID 19837798 DOI: 10.1128/Jb.00937-09  0.397
2009 Malki L, Yanku M, Borovok I, Cohen G, Mevarech M, Aharonowitz Y. Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii. Journal of Bacteriology. 191: 5196-204. PMID 19525351 DOI: 10.1128/Jb.00297-09  0.384
2009 Grinberg I, Shteinberg T, Hassan AQ, Aharonowitz Y, Borovok I, Cohen G. Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: role in nucleotide binding, oligomerization, and DNA interactions. Journal of Bacteriology. 191: 1169-79. PMID 19047342 DOI: 10.1128/Jb.01145-08  0.336
2007 Makhlin J, Kofman T, Borovok I, Kohler C, Engelmann S, Cohen G, Aharonowitz Y. Staphylococcus aureus ArcR controls expression of the arginine deiminase operon Journal of Bacteriology. 189: 5976-5986. PMID 17557828 DOI: 10.1128/Jb.00592-07  0.43
2007 Torrents E, Grinberg I, Gorovitz-Harris B, Lundström H, Borovok I, Aharonowitz Y, Sjöberg BM, Cohen G. NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. Journal of Bacteriology. 189: 5012-21. PMID 17496099 DOI: 10.1128/Jb.00440-07  0.386
2006 Grinberg I, Shteinberg T, Gorovitz B, Aharonowitz Y, Cohen G, Borovok I. The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons. Journal of Bacteriology. 188: 7635-44. PMID 16950922 DOI: 10.1128/Jb.00903-06  0.378
2006 Borovok I, Gorovitz B, Schreiber R, Aharonowitz Y, Cohen G. Coenzyme B12 controls transcription of the Streptomyces class Ia ribonucleotide reductase nrdABS operon via a riboswitch mechanism. Journal of Bacteriology. 188: 2512-20. PMID 16547038 DOI: 10.1128/Jb.188.7.2512-2520.2006  0.34
2005 Gopal S, Borovok I, Ofer A, Yanku M, Cohen G, Goebel W, Kreft J, Aharonowitz Y. A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis. Journal of Bacteriology. 187: 3839-47. PMID 15901709 DOI: 10.1128/Jb.187.11.3839-3847.2005  0.448
2004 Borovok I, Gorovitz B, Yanku M, Schreiber R, Gust B, Chater K, Aharonowitz Y, Cohen G. Alternative oxygen-dependent and oxygen-independent ribonucleotide reductases in Streptomyces: cross-regulation and physiological role in response to oxygen limitation. Molecular Microbiology. 54: 1022-35. PMID 15522084 DOI: 10.1111/J.1365-2958.2004.04325.X  0.386
2004 Lithgow JK, Hayhurst EJ, Cohen G, Aharonowitz Y, Foster SJ. Role of a cysteine synthase in Staphylococcus aureus. Journal of Bacteriology. 186: 1579-90. PMID 14996787 DOI: 10.1128/Jb.186.6.1579-1590.2004  0.403
2004 Uziel O, Borovok I, Schreiber R, Cohen G, Aharonowitz Y. Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress. Journal of Bacteriology. 186: 326-34. PMID 14702300 DOI: 10.1128/Jb.186.2.326-334.2004  0.369
2002 Borovok I, Kreisberg-Zakarin R, Yanko M, Schreiber R, Myslovati M, Aslund F, Holmgren A, Cohen G, Aharonowitz Y. Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth. Microbiology (Reading, England). 148: 391-404. PMID 11832503 DOI: 10.1099/00221287-148-2-391  0.388
2001 Paget MSB, Molle V, Cohen G, Aharonowitz Y, Buttner MJ. Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon. Molecular Microbiology. 42: 1007-1020. PMID 11737643 DOI: 10.1046/J.1365-2958.2001.02675.X  0.386
2001 Masalha M, Borovok I, Schreiber R, Aharonowitz Y, Cohen G. Analysis of Transcription of the Staphylococcus aureus Aerobic Class Ib and Anaerobic Class III Ribonucleotide Reductase Genes in Response to Oxygen Journal of Bacteriology. 183: 7260-7272. PMID 11717286 DOI: 10.1128/Jb.183.24.7260-7272.2001  0.355
2000 Kreisberg-Zakarin R, Borovok I, Yanko M, Frolow F, Aharonowitz Y, Cohen G. Structure-function studies of the non-heme iron active site of isopenicillin N synthase: some implications for catalysis. Biophysical Chemistry. 86: 109-118. PMID 11026676 DOI: 10.1016/S0301-4622(00)00123-X  0.331
1999 Kreisberg-Zakarin R, Borovok I, Yanko M, Aharonowitz Y, Cohen G. Recent advances in the structure and function of isopenicillin N synthase. Antonie Van Leeuwenhoek. 75: 33-9. PMID 10422580 DOI: 10.1023/A:1001723202234  0.344
1998 Gal-Mor O, Borovok I, Av-Gay Y, Cohen G, Aharonowitz Y. Gene organization in the trxA/B-oriC region of the Streptomyces coelicolor chromosome and comparison with other eubacteria Gene. 217: 83-90. PMID 9795152 DOI: 10.1016/S0378-1119(98)00357-6  0.588
1997 Ben-Menachem G, Himmelreich R, Herrmann R, Aharonowitz Y, Rottem S. The thioredoxin reductase system of mycoplasmas. Microbiology (Reading, England). 143: 1933-1940. PMID 9202470 DOI: 10.1099/00221287-143-6-1933  0.302
1997 Landman O, Borovok I, Aharonowitz Y, Cohen G. The glutamine ligand in the ferrous iron active site of isopenicillin N synthase of Streptomyces jumonjinensis is not essential for catalysis Febs Letters. 405: 172-174. PMID 9089285 DOI: 10.1016/S0014-5793(97)00180-4  0.32
1996 Borovok I, Landman O, Kreisberg-Zakarin R, Aharonowitz Y, Cohen G. Ferrous Active Site of Isopenicillin N Synthase: Genetic and Sequence Analysis of the Endogenous Ligands† Biochemistry. 35: 1981-1987. PMID 8639682 DOI: 10.1021/Bi951534T  0.387
1996 Newton GL, Arnold K, Price MS, Sherrill C, Delcardayre SB, Aharonowitz Y, Cohen G, Davies J, Fahey RC, Davis C. Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. Journal of Bacteriology. 178: 1990-5. PMID 8606174 DOI: 10.1128/Jb.178.7.1990-1995.1996  0.51
1995 Newton GL, Bewley CA, Dwyer TJ, Horn R, Aharonowitz Y, Cohen G, Davies J, Faulkner DJ, Fahey RC. The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol. European Journal of Biochemistry / Febs. 230: 821-5. PMID 7607257 DOI: 10.1111/J.1432-1033.1995.0821H.X  0.499
1994 Cohen G, Argaman A, Schreiber R, Mislovati M, Aharonowitz Y. The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis. Journal of Bacteriology. 176: 973-984. PMID 8106340 DOI: 10.1128/Jb.176.4.973-984.1994  0.462
1993 Newton GL, Fahey RC, Cohen G, Aharonowitz Y. Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants. Journal of Bacteriology. 175: 2734-42. PMID 8478335 DOI: 10.1128/Jb.175.9.2734-2742.1993  0.36
1993 Aharonowitz Y, Av-Gay Y, Schreiber R, Cohen G. Characterization of a broad-range disulfide reductase from Streptomyces clavuligerus and its possible role in β-lactam antibiotic biosynthesis Journal of Bacteriology. 175: 623-629. PMID 8423136 DOI: 10.1128/Jb.175.3.623-629.1993  0.618
1993 Cohen G, Yanko M, Mislovati M, Argaman A, Schreiber R, Av-Gay Y, Aharonowitz Y. Thioredoxin-thioredoxin reductase system of Streptomyces clavuligerus: Sequences, expression, and organization of the genes Journal of Bacteriology. 175: 5159-5167. PMID 8349555 DOI: 10.1128/Jb.175.16.5159-5167.1993  0.635
1992 Schwecke T, Aharonowitz Y, Palissa H, Döhren Hv, Kleinkauf H, Liempt Hv. Enzymatic characterisation of the multifunctional enzyme δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine synthetase from Streptomyces clavuligerus Febs Journal. 205: 687-694. PMID 1572368 DOI: 10.1111/J.1432-1033.1992.Tb16830.X  0.339
1992 Aharonowitz Y, Cohen G, Martin JF. Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution. Annual Review of Microbiology. 46: 461-495. PMID 1444264 DOI: 10.1146/Annurev.Mi.46.100192.002333  0.395
1992 Av-gay Y, Aharonowitz Y, Cohen G. Streptomyces contain a 7.0 KDa cold shock like protein Nucleic Acids Research. 20: 5478. PMID 1437568 DOI: 10.1093/Nar/20.20.5478  0.555
1991 Landman O, Shiffman D, Av-Gay Y, Aharonowitz Y, Cohen G. High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies Fems Microbiology Letters. 84: 239-244. PMID 1666621  0.59
1991 Landman O, Shiffman D, Av-Gay Y, Aharonowitz Y, Cohen G. High level expression in Escherichia coli of isopenicillin N synthase genes from Flavobacterium and Streptomyces, and recovery of active enzyme from inclusion bodies Fems Microbiology Letters. 84: 239-244. DOI: 10.1111/J.1574-6968.1991.Tb04603.X  0.426
1990 Shiffman D, Cohen G, Aharonowitz Y, Palissa H, Dohren Hv, KIeinkauf H, Mevarech M. Nucleotide sequence of the isopenicillin N synthase gene (pcbC) of the gram negative Flavobacterium sp. SC 12,154. Nucleic Acids Research. 18: 660-660. PMID 2308852 DOI: 10.1093/Nar/18.3.660  0.362
1990 Landan G, Cohen G, Aharonowitz Y, Shuali Y, Graur D, Shiffman D. Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer. Molecular Biology and Evolution. 7: 399-406. PMID 2263192 DOI: 10.1093/Oxfordjournals.Molbev.A040615  0.368
1990 Cohen G, Shiffman D, Mevarech M, Aharonowitz Y. Microbial isopenicillin N synthase genes: structure, function, diversity and evolution. Trends in Biotechnology. 8: 105-111. PMID 1366527 DOI: 10.1016/0167-7799(90)90148-Q  0.405
1989 Shiffman D, Mevarech M, Jensen SE, Cohen G, Aharonowitz Y. Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces. Molecular & General Genetics : Mgg. 214: 562-9. PMID 3216857 DOI: 10.1007/Bf00330495  0.429
1988 Leskiw BK, Aharonowitz Y, Mevarech M, Wolfe S, Vining LC, Westlake DWS, Jensen SE. Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus Gene. 62: 187-196. PMID 3130293 DOI: 10.1016/0378-1119(88)90557-4  0.309
1988 Keen CL, Mendelovitz S, Cohen G, Aharonowitz Y, Roy KL. Isolation and characterization of a linear DNA plasmid from Streptomyces clavuligerus. Molecular & General Genetics : Mgg. 212: 172-6. PMID 2836705 DOI: 10.1007/Bf00322461  0.342
1988 Granot I, Aharonowitz Y, Freeman A. Cosolvent effect on Δ1-steroid-reductase activity of free and PAAH entrapped Mycobacterium Sp. NRRL B-3805 cells Applied Microbiology and Biotechnology. 27: 457-463. DOI: 10.1007/Bf00451613  0.317
1987 Vining LC, Jensen SE, Westlake DWS, Aharonowitz Y, Wolfe S. Cephamycin production and isopenicillin N synthetase activity in cultures of Streptomyces clavuligerus Applied Microbiology and Biotechnology. 27: 240-246. DOI: 10.1007/Bf00252925  0.311
1986 Jensen SE, Leskiw BK, Vining LC, Aharonowitz Y, Westlake DW, Wolfe S. Purification of isopenicillin N synthetase from Streptomyces clavuligerus Canadian Journal of Microbiology. 32: 953-958. PMID 3815161 DOI: 10.1139/M86-176  0.359
1983 Mendelovitz S, Aharonowitz Y. β-Lactam Antibiotic Production by Streptomyces clavuligerus Mutants Impaired in Regulation of Aspartokinase Microbiology. 129: 2063-2069. PMID 6313854 DOI: 10.1099/00221287-129-7-2063  0.324
1980 Aharonowitz Y. Nitrogen Metabolite Regulation of Antibiotic Biosynthesis Annual Review of Microbiology. 34: 209-233. PMID 6108090 DOI: 10.1146/Annurev.Mi.34.100180.001233  0.331
1979 Aharonowitz Y, Demain AL. Nitrogen nutrition and regulation of cephalosporin production in Streptomyces clavuligerus. Canadian Journal of Microbiology. 25: 61-7. PMID 427656 DOI: 10.1139/M79-010  0.326
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