| Year |
Citation |
Score |
| 2024 |
Horst B, van Duijnen N, Janssen E, Hansen T, Ruijter E. Modular Divergent Synthesis of Indole Alkaloid Derivatives by an Atypical Ugi Multicomponent Reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). e202400477. PMID 38498145 DOI: 10.1002/chem.202400477 |
0.449 |
|
| 2023 |
Preschel HD, Otte RT, Zhuo Y, Ruscoe RE, Burke AJ, Kellerhals R, Horst B, Hennig S, Janssen E, Green AP, Turner NJ, Ruijter E. Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir. The Journal of Organic Chemistry. 88: 12565-12571. PMID 37607396 DOI: 10.1021/acs.joc.3c01274 |
0.343 |
|
| 2022 |
Roose TR, Preschel HD, Mayo Tejedor H, Roozee JC, Hamlin TA, Maes BUW, Ruijter E, Orru RVA. Iron-Catalysed Carbene Transfer to Isocyanides as a Platform for Heterocycle Synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36305372 DOI: 10.1002/chem.202203074 |
0.328 |
|
| 2022 |
Horst B, Verdoorn DS, Hennig S, van der Heijden G, Ruijter E. Enantioselective Total Synthesis of (-)-Limaspermidine and (-)-Kopsinine by a Nitroaryl Transfer Cascade Strategy. Angewandte Chemie (International Ed. in English). e202210592. PMID 36004723 DOI: 10.1002/anie.202210592 |
0.393 |
|
| 2021 |
Faltracco M, Ruijter E. Synthesis of tetracyclic spiroindolines by an interrupted Bischler-Napieralski reaction: total synthesis of akuammicine. Organic & Biomolecular Chemistry. 19: 9641-9644. PMID 34724022 DOI: 10.1039/d1ob01966j |
0.478 |
|
| 2021 |
Faltracco M, Damian M, Ruijter E. Synthesis of Carbazoles and Dihydrocarbazoles by a Divergent Cascade Reaction of Donor-Acceptor Cyclopropanes. Organic Letters. 23: 7592-7596. PMID 34543040 DOI: 10.1021/acs.orglett.1c02795 |
0.424 |
|
| 2021 |
Faltracco M, van de Vrande KNA, Dijkstra M, Saya JM, Hamlin TA, Ruijter E. Pd-Catalyzed Cascade to Benzoxepins by Using Vinyl-Substituted Donor-Acceptor Cyclopropanes. Angewandte Chemie (International Ed. in English). PMID 33822456 DOI: 10.1002/anie.202102862 |
0.408 |
|
| 2021 |
Faltracco M, Ortega-Rosales S, Janssen E, Cioc RC, Vande Velde CML, Ruijter E. Synthesis of Carbazoles by a Diverted Bischler-Napieralski Cascade Reaction. Organic Letters. 23: 3100-3104. PMID 33787266 DOI: 10.1021/acs.orglett.1c00785 |
0.501 |
|
| 2020 |
Collet JW, Roose TR, Weijers B, Maes BUW, Ruijter E, Orru RVA. Recent Advances in Palladium-Catalyzed Isocyanide Insertions. Molecules (Basel, Switzerland). 25. PMID 33114013 DOI: 10.3390/molecules25214906 |
0.411 |
|
| 2020 |
Faltracco M, Sukowski V, van Druenen M, Hamlin TA, Bickelhaupt FM, Ruijter E. Diastereoselective Synthesis of β-Lactams by Ligand-Controlled Stereodivergent Intramolecular Tsuji-Trost Allylation. The Journal of Organic Chemistry. PMID 32584576 DOI: 10.1021/Acs.Joc.0C00575 |
0.521 |
|
| 2020 |
Collet JW, van der Nol EA, Roose TR, Maes BUW, Ruijter E, Orru RVA. Synthesis of Quinazolin-4-ones by Copper Catalyzed Isocyanide Insertion. The Journal of Organic Chemistry. PMID 32400159 DOI: 10.1021/Acs.Joc.0C00771 |
0.522 |
|
| 2020 |
Collet JW, Morel B, Lin HC, Roose TR, Mampuys P, Orru RVA, Ruijter E, Maes BUW. Synthesis of Densely Functionalized Pyrimidouracils by Nickel(II)-Catalyzed Isocyanide Insertion. Organic Letters. PMID 31942797 DOI: 10.1021/Acs.Orglett.9B04387 |
0.53 |
|
| 2020 |
Moni L, Banfi L, Cartagenova D, Cavalli A, Lambruschini C, Martino E, Orru RVA, Ruijter E, Saya JM, Sgrignani J, Riva R. Zinc(II)-mediated diastereoselective Passerini reactions of biocatalytically desymmetrised renewable inputs Organic Chemistry Frontiers. 7: 380-398. DOI: 10.1039/C9Qo00773C |
0.527 |
|
| 2019 |
Saya JM, van Wordragen EDH, Orru RVA, Ruijter E. Mild and Practical Indole C2 Allylation by Allylboration of in situ Generated 3-Chloroindolenines. European Journal of Organic Chemistry. 2019: 5156-5160. PMID 31894179 DOI: 10.1002/Ejoc.201801745 |
0.46 |
|
| 2019 |
Faltracco M, Cotogno S, Vande Velde CML, Ruijter E. Catalytic Asymmetric Synthesis of Diketopiperazines by Intramolecular Tsuji-Trost Allylation. The Journal of Organic Chemistry. 84: 12058-12070. PMID 31446758 DOI: 10.1021/Acs.Joc.9B01994 |
0.553 |
|
| 2019 |
Collet JW, Roose TR, Ruijter E, Maes BUW, Orru R. Base Metal-Catalyzed Isocyanide Insertions. Angewandte Chemie (International Ed. in English). PMID 31287627 DOI: 10.1002/Anie.201905838 |
0.384 |
|
| 2019 |
Saya JM, Ruijter E, Orru RVA. Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30994212 DOI: 10.1002/Chem.201901130 |
0.419 |
|
| 2019 |
Ruijter E, Orru R. Multicomponent reactions in drug discovery and medicinal chemistry. Drug Discovery Today. Technologies. 29: 1-2. PMID 30471667 DOI: 10.1016/J.Ddtec.2018.11.002 |
0.413 |
|
| 2019 |
van der Heijden G, van Schaik TB, Mouarrawis V, de Wit MJM, Velde CMLV, Ruijter E, Orru RVA. Efficient Diastereoselective Three-Component Synthesis of Pipecolic Amides European Journal of Organic Chemistry. 2019: 5313-5325. DOI: 10.1002/Ejoc.201900399 |
0.481 |
|
| 2019 |
Saya JM, Ruijter E, Orru RVA. Frontispiece: Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization Chemistry: a European Journal. 25. DOI: 10.1002/Chem.201983861 |
0.454 |
|
| 2018 |
Braun J, Ariëns MI, Matsuo BT, de Vries S, van Wordragen EDH, Ellenbroek BD, Vande Velde CML, Orru RVA, Ruijter E. Stereoselective Synthesis of Fused Vinylcyclopropanes by Intramolecular Tsuji-Trost Cascade Cyclization. Organic Letters. PMID 30350659 DOI: 10.1021/Acs.Orglett.8B02232 |
0.488 |
|
| 2018 |
Saya JM, Roose TR, Peek JJ, Weijers B, de Waal TJS, Vande Velde CML, Orru RVA, Ruijter E. Iodospirocyclization of Tryptamine-Derived Isocyanides: Formal Total Synthesis of Aspidofractinine. Angewandte Chemie (International Ed. in English). PMID 30273989 DOI: 10.1002/Anie.201809678 |
0.472 |
|
| 2018 |
Mampuys P, Ruijter E, Orru RVA, Maes BUW. Synthesis of Secondary Amides from Thiocarbamates. Organic Letters. 20: 4235-4239. PMID 29975068 DOI: 10.1021/Acs.Orglett.8B01654 |
0.48 |
|
| 2018 |
Saya JM, Berabez R, Broersen P, Schuringa I, Kruithof A, Orru RVA, Ruijter E. Hexafluoroisopropanol as the Acid Component in the Passerini Reaction: One-Pot Access to β-Amino Alcohols. Organic Letters. PMID 29906122 DOI: 10.1021/Acs.Orglett.8B01561 |
0.479 |
|
| 2018 |
Rainoldi G, Begnini F, De Munnik M, Lo Presti L, Vande Velde CML, Orru RVA, Lesma G, Ruijter E, Silvani A. Sequential Multicomponent Strategy for the Diastereoselective Synthesis of Densely Functionalised Spirooxindole-fused Thiazolidines. Acs Combinatorial Science. PMID 29323868 DOI: 10.1021/Acscombsci.7B00179 |
0.533 |
|
| 2018 |
Collet JW, Ackermans K, Lambregts J, Maes BUW, Orru RVA, Ruijter E. Modular Three-Component Synthesis of 4-Aminoquinolines via an Imidoylative Sonogashira/Cyclization Cascade. The Journal of Organic Chemistry. PMID 29260564 DOI: 10.1021/Acs.Joc.7B02844 |
0.57 |
|
| 2018 |
van Lint MJ, Hall M, Faber K, van Spanning RJM, Ruijter E, Orru RVA. Stereoselective Chemoenzymatic Cascade Synthesis of the bis
-THF Core of Acetogenins European Journal of Organic Chemistry. 2019: 1092-1101. DOI: 10.1002/Ejoc.201801562 |
0.466 |
|
| 2018 |
Biemolt J, Ruijter E. Advances in Palladium-Catalyzed Cascade Cyclizations Advanced Synthesis & Catalysis. 360: 3821-3871. DOI: 10.1002/Adsc.201800526 |
0.565 |
|
| 2017 |
Collet JW, Foley C, Shaw AY, Orru RVA, Ruijter E, Hulme C. Copper(i) catalyzed oxidative hydrolysis of Ugi 3-component and Ugi-azide reaction products towards 2° α-ketoamides and α-ketotetrazoles. Organic & Biomolecular Chemistry. PMID 28682397 DOI: 10.1039/C7Ob00881C |
0.406 |
|
| 2017 |
Kruithof A, Vande Velde CM, Ruijter E, Orru RV. Thiazine-2-thiones as Masked 1-Azadienes in Cascade Dimerization Reactions). Molecules (Basel, Switzerland). 22. PMID 28350361 DOI: 10.3390/Molecules22040541 |
0.441 |
|
| 2017 |
Cioc RC, Estévez V, van der Niet DJ, Vande Velde CM, Turrini NG, Hall M, Faber K, Ruijter E, Orru RV. Stereoselective Synthesis of Functionalized Bicyclic Scaffolds by Passerini 3-Center-2-Component Reactions of Cyclic Ketoacids. European Journal of Organic Chemistry. 2017: 1262-1271. PMID 28344504 DOI: 10.1002/Ejoc.201601432 |
0.534 |
|
| 2017 |
Turrini NG, Cioc RC, van der Niet DJH, Ruijter E, Orru RVA, Hall M, Faber K. Biocatalytic access to nonracemic γ-oxo esters via stereoselective reduction using ene-reductases Green Chemistry. 19: 511-518. DOI: 10.1039/C6Gc02493A |
0.366 |
|
| 2017 |
Kruithof A, Mulder JR, Ruiz JM, Janssen E, Mooijman M, Ruijter E, Fonseca Guerra C, Bickelhaupt FM, Orru RVA. Integrative Theory/Experiment-Driven Exploration of a Multicomponent Reaction towards Imidazoline-2-(thi)ones European Journal of Organic Chemistry. 2018: 104-112. DOI: 10.1002/Ejoc.201700941 |
0.509 |
|
| 2016 |
Saya JM, Oppelaar B, Cioc RC, van der Heijden G, Vande Velde CM, Orru RV, Ruijter E. Synthesis of polycyclic spiroindolines by highly diastereoselective interrupted Ugi cascade reactions of 3-(2-isocyanoethyl)indoles. Chemical Communications (Cambridge, England). PMID 27722446 DOI: 10.1039/C6Cc07459F |
0.565 |
|
| 2016 |
van der Heijden G, Kraakman J, Biemolt J, Ruijter E, Orru RV. Metal-free one-pot α-carboxylation of primary alcohols. Organic & Biomolecular Chemistry. PMID 27722407 DOI: 10.1039/C6Ob01813K |
0.363 |
|
| 2016 |
Cioc RC, Schuckman P, Preschel HD, Vlaar T, Ruijter E, Orru RV. Brønsted Acid-Catalyzed Cyanotritylation of Aldehydes by Trityl Isocyanide. Organic Letters. PMID 27404343 DOI: 10.1021/Acs.Orglett.6B01481 |
0.459 |
|
| 2016 |
Mampuys P, Zhu Y, Sergeyev S, Ruijter E, Orru RV, Van Doorslaer S, Maes BU. Iodide-Catalyzed Synthesis of Secondary Thiocarbamates from Isocyanides and Thiosulfonates. Organic Letters. PMID 27276236 DOI: 10.1021/Acs.Orglett.6B01023 |
0.579 |
|
| 2016 |
Cioc RC, Preschel HD, van der Heijden G, Ruijter E, Orru RV. Trityl Isocyanide as a Mechanistic Probe in Multicomponent Chemistry: Walking the Line between Ugi- and Strecker-type Reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27112103 DOI: 10.1002/Chem.201600285 |
0.457 |
|
| 2016 |
van der Heijden G, Jong JA, Ruijter E, Orru RV. 2-Bromo-6-isocyanopyridine as a Universal Convertible Isocyanide for Multicomponent Chemistry. Organic Letters. PMID 26849150 DOI: 10.1021/Acs.Orglett.6B00091 |
0.432 |
|
| 2016 |
Ruijter E, Orru R, Cioc R, Schaepkens van Riempst L, Schuckman P. Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams Synthesis. 49: 1664-1674. DOI: 10.1055/S-0036-1588672 |
0.489 |
|
| 2016 |
Ruijter E, Orru R, Estévez V, Kloeters L, Kwietniewska N, Vicente-García E. Ugi-Type Reactions of Spirocyclic Indolenines as a Platform for Compound Library Generation Synlett. 28: 376-380. DOI: 10.1055/S-0036-1588084 |
0.504 |
|
| 2016 |
de Graaff C, Oppelaar B, Péruch O, Vande Velde CML, Bechi B, Turner NJ, Ruijter E, Orru RVA. Stereoselective Monoamine Oxidase-Catalyzed Oxidative Aza-Friedel-Crafts Reactions ofmeso-Pyrrolidines in Aqueous Buffer Advanced Synthesis & Catalysis. 358: 1555-1560. DOI: 10.1002/Adsc.201600038 |
0.469 |
|
| 2015 |
de Graaff C, Bensch L, Boersma SJ, Cioc RC, van Lint MJ, Janssen E, Turner NJ, Orru RV, Ruijter E. Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction. Angewandte Chemie (International Ed. in English). PMID 26404737 DOI: 10.1002/Anie.201507041 |
0.561 |
|
| 2015 |
de Graaff C, Bensch L, van Lint MJ, Ruijter E, Orru RV. IBX-mediated oxidation of unactivated cyclic amines: application in highly diastereoselective oxidative Ugi-type and aza-Friedel-Crafts reactions. Organic & Biomolecular Chemistry. PMID 26368318 DOI: 10.1039/C5Ob01519G |
0.424 |
|
| 2015 |
Cioc RC, van der Niet DJ, Janssen E, Ruijter E, Orru RV. One-Pot Synthesis of N-Substituted β-Amino Alcohols from Aldehydes and Isocyanides. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 7808-13. PMID 25868115 DOI: 10.1002/Chem.201500210 |
0.451 |
|
| 2015 |
Kruithof A, Ruijter E, Orru RV. Synthesis of heterocycles by formal cycloadditions of isocyanides. Chemistry, An Asian Journal. 10: 508-20. PMID 25504958 DOI: 10.1002/Asia.201403207 |
0.557 |
|
| 2015 |
Bouwman S, Orru RV, Ruijter E. Stereoselective synthesis of fluorinated aminoglycosyl phosphonates. Organic & Biomolecular Chemistry. 13: 1317-21. PMID 25491168 DOI: 10.1039/C4Ob02317J |
0.485 |
|
| 2014 |
Janssen GV, Janssen E, Vande Velde CM, Ehlers AW, Slootweg JC, Ruijter E, Lammertsma K, Orru RV. Chemoselective addition of isocyanides to N-tert-butanesulfinimines. Organic Letters. 16: 5116-9. PMID 25229182 DOI: 10.1021/Ol502463S |
0.461 |
|
| 2014 |
Mampuys P, Zhu Y, Vlaar T, Ruijter E, Orru RV, Maes BU. Sustainable three-component synthesis of isothioureas from isocyanides, thiosulfonates, and amines. Angewandte Chemie (International Ed. in English). 53: 12849-54. PMID 25223494 DOI: 10.1002/Anie.201406717 |
0.522 |
|
| 2014 |
Janssen GV, Slobbe P, Mooijman M, Kruithof A, Ehlers AW, Guerra CF, Bickelhaupt FM, Slootweg JC, Ruijter E, Lammertsma K, Orru RV. Diastereoselective one-pot synthesis of tetrafunctionalized 2-imidazolines. The Journal of Organic Chemistry. 79: 5219-26. PMID 24820129 DOI: 10.1021/Jo500790N |
0.57 |
|
| 2014 |
Koopmanschap G, Ruijter E, Orru RV. Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics. Beilstein Journal of Organic Chemistry. 10: 544-98. PMID 24605172 DOI: 10.3762/Bjoc.10.50 |
0.487 |
|
| 2014 |
Cioc RC, Ruijter E, Orru RVA. Multicomponent reactions: Advanced tools for sustainable organic synthesis Green Chemistry. 16: 2958-2975. DOI: 10.1039/C4Gc00013G |
0.52 |
|
| 2014 |
Estévez V, Van Baelen G, Lentferink BH, Vlaar T, Janssen E, Maes BUW, Orru RVA, Ruijter E. Synthesis of pyridopyrimidines by palladium-catalyzed isocyanide insertion Acs Catalysis. 4: 40-43. DOI: 10.1021/Cs400926Z |
0.499 |
|
| 2014 |
Janssen GV, Vicente-García E, Vogel W, Slootweg JC, Ruijter E, Lammertsma K, Orru RVA. Stereoselective synthesis of -sulfinylamino isocyanides and 2-imidazolines European Journal of Organic Chemistry. 2014: 3762-3766. DOI: 10.1002/Ejoc.201402210 |
0.434 |
|
| 2014 |
Rombouts JA, Ravensbergen J, Frese RN, Kennis JTM, Ehlers AW, Slootweg JC, Ruijter E, Lammertsma K, Orru RVA. Cover Picture: Synthesis and Photophysics of a Red-Light Absorbing Supramolecular Chromophore System (Chem. Eur. J. 33/2014) Chemistry - a European Journal. 20: 10181-10181. DOI: 10.1002/Chem.201490137 |
0.318 |
|
| 2014 |
Vlaar T, Bensch L, Kraakman J, Vande Velde CML, Maes BUW, Orru RVA, Ruijter E. Synthesis of diverse azolo[c]quinazolines by palladium(II)- catalyzed aerobic oxidative insertion of isocyanides Advanced Synthesis and Catalysis. 356: 1205-1209. DOI: 10.1002/Adsc.201301129 |
0.381 |
|
| 2013 |
Vlaar T, Orru RV, Maes BU, Ruijter E. Palladium-catalyzed synthesis of 2-aminobenzoxazinones by aerobic oxidative coupling of anthranilic acids and isocyanides. The Journal of Organic Chemistry. 78: 10469-75. PMID 24063265 DOI: 10.1021/Jo401924H |
0.474 |
|
| 2013 |
Ruijter E, Orru RV. Multicomponent reactions - opportunities for the pharmaceutical industry. Drug Discovery Today. Technologies. 10: e15-20. PMID 24050225 DOI: 10.1016/J.Ddtec.2012.10.012 |
0.51 |
|
| 2013 |
Vlaar T, Mampuys P, Helliwell M, Maes BU, Orru RV, Ruijter E. Multicomponent synthesis of 4-aminophthalazin-1(2H)-ones by palladium-catalyzed isocyanide insertion. The Journal of Organic Chemistry. 78: 6735-45. PMID 23768066 DOI: 10.1021/Jo401131P |
0.455 |
|
| 2013 |
Vlaar T, Ruijter E, Maes BU, Orru RV. Palladium-catalyzed migratory insertion of isocyanides: an emerging platform in cross-coupling chemistry. Angewandte Chemie (International Ed. in English). 52: 7084-97. PMID 23754476 DOI: 10.1002/Anie.201300942 |
0.568 |
|
| 2013 |
Van Der Heijden G, Ruijter E, Orru RVA. Efficiency, diversity, and complexity with multicomponent reactions Synlett. 24: 666-685. DOI: 10.1055/S-0032-1318222 |
0.558 |
|
| 2013 |
Vlaar T, Maes BUW, Ruijter E, Orru RVA. Synthesis of 4-aminoquinolines by aerobic oxidative palladium-catalyzed double C-H activation and isocyanide insertion Chemistry of Heterocyclic Compounds. 49: 902-908. DOI: 10.1007/S10593-013-1324-Z |
0.353 |
|
| 2013 |
Kruithof A, Ruijter E, Orru RVA. Microwave-Assisted Multicomponent Reactions in the Synthesis of Heterocycles Microwaves in Organic Synthesis: Third Edition. 2: 1099-1171. DOI: 10.1002/9783527651313.ch24 |
0.501 |
|
| 2012 |
Vlaar T, Cioc RC, Mampuys P, Maes BU, Orru RV, Ruijter E. Sustainable synthesis of diverse privileged heterocycles by palladium-catalyzed aerobic oxidative isocyanide insertion. Angewandte Chemie (International Ed. in English). 51: 13058-61. PMID 23161862 DOI: 10.1002/Anie.201207410 |
0.347 |
|
| 2012 |
de Graaff C, Ruijter E, Orru RV. Recent developments in asymmetric multicomponent reactions. Chemical Society Reviews. 41: 3969-4009. PMID 22546840 DOI: 10.1039/C2Cs15361K |
0.578 |
|
| 2012 |
Kruithof A, Ploeger ML, Janssen E, Helliwell M, de Kanter FJ, Ruijter E, Orru RV. Multicomponent synthesis of 3,6-dihydro-2H-1,3-thiazine-2-thiones. Molecules (Basel, Switzerland). 17: 1675-85. PMID 22318323 DOI: 10.3390/Molecules17021675 |
0.486 |
|
| 2012 |
Znabet A, Blanken S, Janssen E, de Kanter FJ, Helliwell M, Turner NJ, Ruijter E, Orru RV. Stereoselective synthesis of N-aryl proline amides by biotransformation-Ugi-Smiles sequence. Organic & Biomolecular Chemistry. 10: 941-4. PMID 22179495 DOI: 10.1039/C1Ob06699D |
0.406 |
|
| 2012 |
Broere DLJ, Ruijter E. Recent Advances in Transition-Metal-Catalyzed [2+2+2]-Cyclo(co)trimerization Reactions Synthesis. 44: 2639-2672. DOI: 10.1055/S-0032-1316757 |
0.558 |
|
| 2012 |
Mooijman M, Bon RS, Sprenkels NE, Van Oosterhout HN, De Kanter FJJ, Groen MB, Ruijter E, Orru RVA. Synthesis of imidazolidine-2-(thi)ones via C2-selective oxidation and thionation of 2-imidazolinium halides Synlett. 80-84. DOI: 10.1055/S-0031-1290087 |
0.484 |
|
| 2012 |
Slobbe P, Ruijter E, Orru RVA. Recent applications of multicomponent reactions in medicinal chemistry Medchemcomm. 3: 1189-1218. DOI: 10.1039/C2Md20089A |
0.491 |
|
| 2012 |
Den Heeten R, Van Der Boon LJP, Broere DLJ, Janssen E, De Kanter FJJ, Ruijter E, Orru RVA. Concise synthesis of highly substituted benzo[a]quinolizines by a multicomponent reaction/allylation/heck reaction sequence European Journal of Organic Chemistry. 275-280. DOI: 10.1002/Ejoc.201101170 |
0.54 |
|
| 2011 |
Van Baelen G, Kuijer S, Rý?ek L, Sergeyev S, Janssen E, de Kanter FJ, Maes BU, Ruijter E, Orru RV. Synthesis of 4-aminoquinazolines by palladium-catalyzed intramolecular imidoylation of N-(2-bromoaryl)amidines. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 15039-44. PMID 22125085 DOI: 10.1002/Chem.201102468 |
0.523 |
|
| 2011 |
Vlaar T, Ruijter E, Znabet A, Janssen E, de Kanter FJ, Maes BU, Orru RV. Palladium-catalyzed synthesis of 4-aminophthalazin-1(2H)-ones by isocyanide insertion. Organic Letters. 13: 6496-9. PMID 22085248 DOI: 10.1021/Ol202784D |
0.432 |
|
| 2011 |
Ruijter E, Scheffelaar R, Orru RV. Multicomponent reaction design in the quest for molecular complexity and diversity. Angewandte Chemie (International Ed. in English). 50: 6234-46. PMID 21710674 DOI: 10.1002/Anie.201006515 |
0.484 |
|
| 2011 |
Mehta VP, Modha SG, Ruijter E, Van Hecke K, Van Meervelt L, Pannecouque C, Balzarini J, Orru RV, Van der Eycken E. A microwave-assisted diastereoselective multicomponent reaction to access dibenzo[c,e]azepinones: synthesis and biological evaluation. The Journal of Organic Chemistry. 76: 2828-39. PMID 21391618 DOI: 10.1021/Jo200251Q |
0.427 |
|
| 2011 |
Kruithof A, Ruijter E, Orru RVA. Microwave-assisted multicomponent synthesis of heterocycles Current Organic Chemistry. 15: 204-236. DOI: 10.2174/138527211793979817 |
0.493 |
|
| 2011 |
Coffinier D, Kaim LE, Grimaud L, Ruijter E, Orru RVA. A new multicomponent reaction for the synthesis of pyridines via cycloaddition of azadienes and ketenimines Tetrahedron Letters. 52: 3023-3025. DOI: 10.1016/J.Tetlet.2011.04.007 |
0.569 |
|
| 2011 |
den Heeten R, van der Boon LJP, Broere DLJ, Janssen E, de Kanter FJJ, Ruijter E, Orru RVA. Concise Synthesis of Highly Substituted Benzo[a]quinolizines by a Multicomponent Reaction/Allylation/Heck Reaction Sequence (Eur. J. Org. Chem. 2/2012) European Journal of Organic Chemistry. 2012: n/a-n/a. DOI: 10.1002/Ejoc.201190110 |
0.559 |
|
| 2011 |
Vlaar T, Ruijter E, Orru RVA. Corrigendum: Recent Advances in Palladium-Catalyzed Cascade Cyclizations Advanced Synthesis & Catalysis. 353: 1405-1405. DOI: 10.1002/Adsc.201190023 |
0.467 |
|
| 2011 |
Vlaar T, Ruijter E, Orru RVA. Recent advances in palladium-catalyzed cascade cyclizations Advanced Synthesis and Catalysis. 353: 809-841. DOI: 10.1002/Adsc.201000979 |
0.527 |
|
| 2010 |
Strassberger Z, Mooijman M, Ruijter E, Alberts AH, Maldonado AG, Orru RV, Rothenberg G. Finding Furfural Hydrogenation Catalysts via Predictive Modelling. Advanced Synthesis & Catalysis. 352: 2201-2210. PMID 23193388 DOI: 10.1002/Adsc.201000308 |
0.305 |
|
| 2010 |
Znabet A, Zonneveld J, Janssen E, De Kanter FJ, Helliwell M, Turner NJ, Ruijter E, Orru RV. Asymmetric synthesis of synthetic alkaloids by a tandem biocatalysis/Ugi/Pictet-Spengler-type cyclization sequence. Chemical Communications (Cambridge, England). 46: 7706-8. PMID 20871902 DOI: 10.1039/C0Cc02938F |
0.52 |
|
| 2010 |
Znabet A, Polak MM, Janssen E, de Kanter FJ, Turner NJ, Orru RV, Ruijter E. A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions. Chemical Communications (Cambridge, England). 46: 7918-20. PMID 20856952 DOI: 10.1039/C0Cc02823A |
0.55 |
|
| 2010 |
Znabet A, Ruijter E, de Kanter FJ, Köhler V, Helliwell M, Turner NJ, Orru RV. Highly stereoselective synthesis of substituted prolyl peptides using a combination of biocatalytic desymmetrization and multicomponent reactions. Angewandte Chemie (International Ed. in English). 49: 5289-92. PMID 20575127 DOI: 10.1002/Anie.201001592 |
0.495 |
|
| 2010 |
Scheffelaar R, Paravidino M, Znabet A, Schmitz RF, de Kanter FJ, Lutz M, Spek AL, Fonseca Guerra C, Bickelhaupt FM, Groen MB, Ruijter E, Orru RV. Scope and limitations of an efficient four-component reaction for dihydropyridin-2-ones. The Journal of Organic Chemistry. 75: 1723-32. PMID 20121230 DOI: 10.1021/Jo902613J |
0.473 |
|
| 2010 |
Ruijter E, Garcia-Hartjes J, Hoffmann F, Vanwandelen LTM, Dekanter FJJ, Janssen E, Orru RVA. Synthesis of polycyclic alkaloid-type compounds by an N -acyliminium Pictet-Spengler/diels-alder sequence Synlett. 2485-2489. DOI: 10.1055/S-0030-1258057 |
0.505 |
|
| 2010 |
Orru R, Znabet A, Ruijter E, de Kanter F, Köhler V, Helliwell M, Turner N. Complex Prolyl Peptides in Two Steps: Biocatalysis and Ugi Reaction Synfacts. 2010: 1067-1067. DOI: 10.1055/S-0030-1257963 |
0.417 |
|
| 2010 |
Strassberger Z, Mooijman M, Ruijter E, Alberts AH, De Graaff C, Orru RVA, Rothenberg G. A facile route to ruthenium-carbene complexes and their application in furfural hydrogenation Applied Organometallic Chemistry. 24: 142-146. DOI: 10.1002/Aoc.1584 |
0.442 |
|
| 2009 |
Elders N, van der Born D, Hendrickx LJ, Timmer BJ, Krause A, Janssen E, de Kanter FJ, Ruijter E, Orru RV. The efficient one-pot reaction of up to eight components by the union of multicomponent reactions. Angewandte Chemie (International Ed. in English). 48: 5856-9. PMID 19579257 DOI: 10.1002/Anie.200902683 |
0.51 |
|
| 2009 |
Elders N, Ruijter E, de Kanter FJ, Janssen E, Lutz M, Spek AL, Orru RV. A multicomponent reaction towards N-(cyanomethyl)amides. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 6096-9. PMID 19462390 DOI: 10.1002/Chem.200900785 |
0.563 |
|
| 2009 |
Scheffelaar R, Nijenhuis RA, Paravidino M, Lutz M, Spek AL, Ehlers AW, de Kanter FJ, Groen MB, Orru RV, Ruijter E. Synthesis of conformationally constrained peptidomimetics using multicomponent reactions. The Journal of Organic Chemistry. 74: 660-8. PMID 19055378 DOI: 10.1021/Jo802052J |
0.407 |
|
| 2009 |
Scheffelaar R, Paravidino M, Muilwijk D, Lutz M, Spek AL, de Kanter FJ, Orru RV, Ruijter E. A novel three-component reaction toward dihydrooxazolopyridines. Organic Letters. 11: 125-8. PMID 19053816 DOI: 10.1021/Ol802515V |
0.555 |
|
| 2008 |
Groenendaal B, Ruijter E, Orru RV. 1-Azadienes in cycloaddition and multicomponent reactions towards N-heterocycles. Chemical Communications (Cambridge, England). 5474-89. PMID 18997927 DOI: 10.1039/B809206K |
0.56 |
|
| 2008 |
Groenendaal B, Ruijter E, de Kanter FJ, Lutz M, Spek AL, Orru RV. Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones. Organic & Biomolecular Chemistry. 6: 3158-65. PMID 18698475 DOI: 10.1039/B807138A |
0.527 |
|
| 2008 |
Elders N, Ruijter E, de Kanter FJ, Groen MB, Orru RV. Selective formation of 2-imidazolines and 2-substituted oxazoles by using a three-component reaction. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4961-73. PMID 18431735 DOI: 10.1002/Chem.200800271 |
0.525 |
|
| 2008 |
Groenendaal B, Vugts DJ, Schmitz RF, de Kanter FJ, Ruijter E, Groen MB, Orru RV. A multicomponent synthesis of triazinane diones. The Journal of Organic Chemistry. 73: 719-22. PMID 18095703 DOI: 10.1021/Jo701973D |
0.534 |
|
| 2008 |
Vugts DJ, Aktas H, Al-Mafraji K, De Kanter FJJ, Ruijter E, Groen MB, Orru RVA. Synthesis of 3′-deoxyribolactones using a hydrolysis-induced lactonization cascade reaction of epoxy cyanohydrins European Journal of Organic Chemistry. 1336-1339. DOI: 10.1002/Ejoc.200701152 |
0.545 |
|
| 2007 |
Paravidino M, Scheffelaar R, Schmitz RF, Kanter FJ, Groen MB, Ruijter E, Orru RV. A flexible six-component reaction to access constrained depsipeptides based on a dihydropyridinone core. The Journal of Organic Chemistry. 72: 10239-42. PMID 17997575 DOI: 10.1021/Jo701978V |
0.513 |
|
| 2007 |
Elders N, Schmitz RF, de Kanter FJ, Ruijter E, Groen MB, Orru RV. A resource-efficient and highly flexible procedure for a three-component synthesis of 2-imidazolines. The Journal of Organic Chemistry. 72: 6135-42. PMID 17628108 DOI: 10.1021/Jo070840X |
0.497 |
|
| 2005 |
van der Veken P, Dirksen EH, Ruijter E, Elgersma RC, Heck AJ, Rijkers DT, Slijper M, Liskamp RM. Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides. Chembiochem : a European Journal of Chemical Biology. 6: 2271-80. PMID 16254931 DOI: 10.1002/Cbic.200500209 |
0.316 |
|
| 2005 |
Wessjohann LA, Ruijter E, Garcia-Rivera D, Brandt W. What can a chemist learn from nature's macrocycles?--a brief, conceptual view. Molecular Diversity. 9: 171-86. PMID 15789564 DOI: 10.1007/S11030-005-1314-X |
0.524 |
|
| 2005 |
Wessjohann LA, Ruijter E. Macrocycles rapidly produced by multiple multicomponent reactions including bifunctional building blocks (MiBs). Molecular Diversity. 9: 159-69. PMID 15789563 DOI: 10.1007/S11030-005-1313-Y |
0.683 |
|
| 2005 |
Ruijter E, Schültingkemper H, Wessjohann LA. Highly substituted tetrahydropyrones from hetero-Diels-Alder reactions of 2-alkenals with stereochemical induction from chiral dienes. The Journal of Organic Chemistry. 70: 2820-3. PMID 15787578 DOI: 10.1021/Jo0488311 |
0.671 |
|
| 2005 |
Zhu M, Ruijter E, Wessjohann LA. New scavenger resin for the reversible linking and monoprotection of functionalized aromatic aldehydes. Organic Letters. 6: 3921-4. PMID 15496064 DOI: 10.1021/Ol048610H |
0.597 |
|
| 2005 |
Wessjohann LA, Ruijter E. Strategies for Total and Diversity-Oriented Synthesis of Natural Product(-like) Macrocycles Cheminform. 36. DOI: 10.1007/B96883 |
0.588 |
|
| 2004 |
Scheid G, Ruijter E, Konarzycka-Bessler M, Bornscheuer UT, Wessjohann LA. Synthesis and resolution of a key building block for epothilones: a comparison of asymmetric synthesis, chemical and enzymatic resolution Tetrahedron: Asymmetry. 15: 2861-2869. DOI: 10.1016/J.Tetasy.2004.06.048 |
0.563 |
|
| 2004 |
Scheid G, Kuit W, Ruijter E, Orru RVA, Henke E, Bornscheuer U, Wessjohann LA. A new route to protected acyloins and their enzymatic resolution with lipases European Journal of Organic Chemistry. 1063-1074. DOI: 10.1002/Ejoc.200300338 |
0.533 |
|
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