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Lu Zhou - Publications

Affiliations: 
Fudan university, Shanghai, Shanghai Shi, China 
Area:
Chemistry
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14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wen CL, Huang K, Jiang LL, Lu XX, Dai YT, Shi MM, Tang XM, Wang QB, Zhang XD, Wang PH, Li HT, Ruan XX, Wang LW, Wang XJ, Wang Q, ... ... Zhou L, et al. An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 31662475 DOI: 10.1073/Pnas.1914557116  0.318
2019 Huang K, Liang Q, Zhou Y, Jiang LL, Gu WM, Luo MY, Tang YB, Wang Y, Lu W, Huang M, Zhang SZ, Zhuang GL, Dai Q, Shen QC, Zhang J, ... ... Zhou L, et al. A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer. Cell Metabolism. PMID 31607564 DOI: 10.1016/J.Cmet.2019.09.014  0.335
2019 Huang K, Jiang L, Li H, Ye D, Zhou L. Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors. Molecules (Basel, Switzerland). 24. PMID 30818883 DOI: 10.3390/Molecules24050845  0.334
2019 Huang K, Jiang L, Liang R, Li H, Ruan X, Shan C, Ye D, Zhou L. Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment. European Journal of Medicinal Chemistry. 168: 45-57. PMID 30798052 DOI: 10.1016/J.Ejmech.2019.01.085  0.36
2018 Li Y, Huang T, Lou B, Ye D, Qi X, Li X, Hu S, Ding T, Chen Y, Cao Y, Mo M, Dong J, Wei M, Chu Y, Li H, ... ... Zhou L, et al. Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor. European Journal of Medicinal Chemistry. 163: 864-882. PMID 30580239 DOI: 10.1016/J.Ejmech.2018.12.028  0.318
2018 Mo M, Yang J, Jiang XC, Cao Y, Fei J, Chen Y, Qi X, Chu Y, Zhou L, Ye D. Discovery of 4-Benzyloxybenzo[d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/db Mice. Journal of Medicinal Chemistry. PMID 30074791 DOI: 10.1021/Acs.Jmedchem.8B00727  0.313
2018 Wang P, Jiang L, Cao Y, Ye D, Zhou L. The Design and Synthesis of -Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors. Molecules (Basel, Switzerland). 23. PMID 29890679 DOI: 10.3390/Molecules23061396  0.338
2018 Wang P, Jiang L, Cao Y, Zhang X, Chen B, Zhang S, Huang K, Ye D, Zhou L. Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry. PMID 29530347 DOI: 10.1016/J.Bmc.2018.02.044  0.347
2017 Qi XY, Cao Y, Li YL, Mo MG, Zhou L, Ye DY. Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine. Bioorganic & Medicinal Chemistry Letters. PMID 28619536 DOI: 10.1016/J.Bmcl.2017.05.074  0.338
2016 Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, et al. Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. Molecular Cell. PMID 27867011 DOI: 10.1016/J.Molcel.2016.10.014  0.309
2015 Li YL, Qi XY, Jiang H, Deng XD, Dong YP, Ding TB, Zhou L, Men P, Chu Y, Wang RX, Jiang XC, Ye DY. Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors. Bioorganic & Medicinal Chemistry. 23: 6173-84. PMID 26314925 DOI: 10.1016/J.Bmc.2015.07.060  0.329
2015 Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, ... ... Zhou L, et al. Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Molecular Cell. PMID 26145173 DOI: 10.1016/J.Molcel.2015.05.037  0.304
2014 Deng X, Lin F, Zhang Y, Li Y, Zhou L, Lou B, Li Y, Dong J, Ding T, Jiang X, Wang R, Ye D. Identification of small molecule sphingomyelin synthase inhibitors. European Journal of Medicinal Chemistry. 73: 1-7. PMID 24374347 DOI: 10.1016/J.Ejmech.2013.12.002  0.331
2013 Gao X, Gong H, Men P, Zhou L, Ye D. Design, Synthesis, and Biological Evaluation of Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase Chinese Journal of Chemistry. 31: 1164-1170. DOI: 10.1002/Cjoc.201300079  0.314
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