Daniel Madsen - Publications

2018 Chemistry University of Copenhagen, København, Denmark 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Rømer AMA, Thorseth ML, Madsen DH. Immune Modulatory Properties of Collagen in Cancer. Frontiers in Immunology. 12: 791453. PMID 34956223 DOI: 10.3389/fimmu.2021.791453  1
2021 Aaboe Jørgensen M, Ugel S, Hübbe ML, Carretta M, Perez-Penco M, Weis-Banke SE, Martinenaite E, Kopp K, Chapellier M, Adamo A, De Sanctis F, Frusteri C, Iezzi M, Zocca MB, Madsen DH, et al. Arginase 1-based immune modulatory vaccines induce anti-cancer immunity and synergize with anti-PD-1 checkpoint blockade. Cancer Immunology Research. PMID 34518197 DOI: 10.1158/2326-6066.CIR-21-0280  1
2021 Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, ... ... Madsen DE, et al. FVIIIa-mimetic bispecific antibody (Mim8) ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood. PMID 34077951 DOI: 10.1182/blood.2020010331  1
2021 Di Leo L, Bodemeyer V, Bosisio FM, Claps G, Carretta M, Rizza S, Faienza F, Frias A, Khan S, Bordi M, Pacheco MP, Di Martino J, Bravo-Cordero JJ, Daniel CJ, Sears RC, ... ... Madsen DH, et al. Loss of Ambra1 promotes melanoma growth and invasion. Nature Communications. 12: 2550. PMID 33953176 DOI: 10.1038/s41467-021-22772-2  1
2021 Petersen LK, Christensen AB, Andersen J, Folkesson CG, Kristensen O, Andersen C, Alzu A, Sløk FA, Blakskjær P, Madsen D, Azevedo C, Micco I, Hansen NJV. Screening of DNA-Encoded Small Molecule Libraries inside a Living Cell. Journal of the American Chemical Society. 143: 2751-2756. PMID 33577316 DOI: 10.1021/jacs.0c09213  1
2021 Madsen DA, Schmidt SI, Blaabjerg M, Meyer M. Interaction between Parkin and -Synuclein in -Mediated Parkinson's Disease. Cells. 10. PMID 33572534 DOI: 10.3390/cells10020283  0.01
2020 Jensen C, Sinkeviciute D, Madsen DH, Önnerfjord P, Hansen M, Schmidt H, Karsdal MA, Svane IM, Willumsen N. Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade. Cancers. 12. PMID 32998446 DOI: 10.3390/cancers12102786  1
2020 Larsen AMH, Kuczek DE, Kalvisa A, Siersbæk MS, Thorseth ML, Johansen AZ, Carretta M, Grøntved L, Vang O, Madsen DH. Collagen Density Modulates the Immunosuppressive Functions of Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 205: 1461-1472. PMID 32839214 DOI: 10.4049/jimmunol.1900789  1
2020 Wang Y, Oliveira MT, Madsen D, Thompson A, Meldal M, Diness F. Dihydroquinazolinones via A3-Type Reactions of N-Carbamoyliminium Ions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32790088 DOI: 10.1002/Chem.202003117  1
2020 Madsen D, Azevedo C, Micco I, Petersen LK, Hansen NJV. An overview of DNA-encoded libraries: A versatile tool for drug discovery. Progress in Medicinal Chemistry. 59: 181-249. PMID 32362328 DOI: 10.1016/bs.pmch.2020.03.001  1
2020 Jürgensen HJ, van Putten S, Nørregaard KS, Bugge TH, Engelholm LH, Behrendt N, Madsen DH. Cellular uptake of collagens and implications for immune cell regulation in disease. Cellular and Molecular Life Sciences : Cmls. 77: 3161-3176. PMID 32100084 DOI: 10.1007/s00018-020-03481-3  1
2020 Madsen D, Jørgensen FP, Palmer D, Roux M, Olsen JV, Bols M, Schoffelen S, Diness F, Meldal M. Design and Combinatorial Development of Shield-1 Peptide Mimetics Binding to Destabilized FKBP12. Acs Combinatorial Science. PMID 32027120 DOI: 10.1021/Acscombsci.9B00197  1
2020 Jensen C, Sinkeviciute D, Madsen DH, Önnerfjord P, Hansen M, Schmidt H, Svane IM, Karsdal MA, Willumsen N. Abstract 3091: Liquid biopsy reflecting a T-cell permissive tumor microenvironment identifies metastatic melanoma patients responding to immune checkpoint inhibitor therapy Clinical Trials. DOI: 10.1158/1538-7445.Am2020-3091  1
2019 Jürgensen HJ, Silva LM, Krigslund O, van Putten S, Madsen DH, Behrendt N, Engelholm LH, Bugge TH. CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets. Matrix Biology Plus. 1: 100003. PMID 33543002 DOI: 10.1016/j.mbplus.2019.03.002  1
2019 Christensen LFB, Schafer N, Wolf-Perez A, Madsen DJ, Otzen DE. Bacterial Amyloids: Biogenesis and Biomaterials. Advances in Experimental Medicine and Biology. 1174: 113-159. PMID 31713198 DOI: 10.1007/978-981-13-9791-2_4  1
2019 Jorgesen FP, Madsen D, Meldal M, Olsen JV, Petersen M, Granhøj J, Bols M. Synthesis of Shld derivatives, their binding the Destabilizing Domain and influence on protein accumulation in transgenic plants. Journal of Medicinal Chemistry. PMID 31059249 DOI: 10.1021/Acs.Jmedchem.9B00497  1
2019 Kuczek DE, Larsen AMH, Thorseth ML, Carretta M, Kalvisa A, Siersbæk MS, Simões AMC, Roslind A, Engelholm LH, Noessner E, Donia M, Svane IM, Straten PT, Grøntved L, Madsen DH. Collagen density regulates the activity of tumor-infiltrating T cells. Journal For Immunotherapy of Cancer. 7: 68. PMID 30867051 DOI: 10.1186/s40425-019-0556-6  1
2019 Jürgensen HJ, Nørregaard KS, Sibree MM, Santoni-Rugiu E, Madsen DH, Wassilew K, Krustrup D, Garred P, Bugge TH, Engelholm LH, Behrendt N. Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. The Journal of Cell Biology. 218: 333-349. PMID 30366943 DOI: 10.1083/jcb.201802148  1
2019 Willumsen N, Bager CL, Jensen C, Karsdal MA, Madsen DH, Hansen M, Schmidt H, Svane IM. Assessment of extracellular matrix and tissue derived metabolites in a liquid biopsy for identifying endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.E14050  1
2019 Willumsen N, Bager CL, Jensen C, Karsdal MA, Madsen DH, Hansen M, Schmidt H, Svane IM. Extracellular matrix and tissue derived metabolites in a liquid biopsy identifies endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz253.075  1
2018 Jensen C, Madsen DH, Hansen M, Schmidt H, Svane IM, Karsdal MA, Willumsen N. Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients. Journal For Immunotherapy of Cancer. 6: 152. PMID 30567561 DOI: 10.1186/S40425-018-0474-Z  1
2018 Bleem A, Christiansen G, Madsen DJ, Maric H, Strømgaard K, Bryers JD, Daggett V, Meyer RL, Otzen DE. Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms. Journal of Molecular Biology. PMID 29964047 DOI: 10.1016/J.Jmb.2018.06.043  1
2018 Jensen C, Madsen D, Hansen M, Schmidt H, Svane I, Karsdal M, Willumsen N. Altered type III collagen turnover measured in pre-treatment serum predicts outcome in metastatic melanoma patients treated with Ipilimumab European Journal of Cancer. 92. DOI: 10.1016/J.Ejca.2018.01.019  1
2017 Madsen DH, Jürgensen HJ, Siersbæk MS, Kuczek DE, Grey Cloud L, Liu S, Behrendt N, Grøntved L, Weigert R, Bugge TH. Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake. Cell Reports. 21: 3662-3671. PMID 29281816 DOI: 10.1016/j.celrep.2017.12.011  1
2017 Kaspersen JD, Søndergaard A, Madsen DJ, Otzen DE, Pedersen JS. Refolding of SDS-Unfolded Proteins by Nonionic Surfactants. Biophysical Journal. 112: 1609-1620. PMID 28445752 DOI: 10.1016/j.bpj.2017.03.013  1
2017 Madsen DE, Nichols TC, Merricks EP, Waters EK, Wiinberg B. Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo. Plos One. 12: e0175030. PMID 28384182 DOI: 10.1371/journal.pone.0175030  0.01
2017 Jensen C, Madsen DH, Hansen M, Schmidt H, Svane I, Karsdal MA, Willumsen N. 33PSerological assessment of extracellular matrix (ECM) remodeling in relation to clinical response in metastatic melanoma patients treated with ipilimumab Annals of Oncology. 28. DOI: 10.1093/Annonc/Mdx711.014  1
2016 Agerschou ED, Christiansen G, Schafer NP, Madsen DJ, Brodersen DE, Semsey S, Otzen DE. The transcriptional regulator GalR self-assembles to form highly regular tubular structures. Scientific Reports. 6: 27672. PMID 27279285 DOI: 10.1038/srep27672  1
2016 Friis S, Madsen DH, Bugge TH. Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin. The Journal of Biological Chemistry. 291: 2577-82. PMID 26719335 DOI: 10.1074/jbc.C115.706721  1
2016 Engelholm LH, Melander MC, Hald A, Persson M, Madsen DH, Jürgensen HJ, Johansson K, Nielsen C, Nørregaard KS, Ingvarsen SZ, Kjaer A, Trovik CS, Laerum OD, Bugge TH, Eide J, et al. Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180. The Journal of Pathology. 238: 120-33. PMID 26466547 DOI: 10.1002/path.4661  1
2015 Fan MH, Zhu Q, Li HH, Ra HJ, Majumdar S, Gulick DL, Jerome JA, Madsen DH, Christofidou-Solomidou M, Speicher DW, Bachovchin WW, Feghali-Bostwick C, Pur Eacute E. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lung in Mice. The Journal of Biological Chemistry. PMID 26663085 DOI: 10.1074/Jbc.M115.701433  1
2015 Motley MP, Madsen DH, Jürgensen HJ, Spencer DE, Szabo R, Holmbeck K, Flick MJ, Lawrence DA, Castellino FJ, Weigert R, Bugge TH. A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo. Blood. PMID 26647393 DOI: 10.1182/Blood-2015-05-644260  1
2015 Melander MC, Jürgensen HJ, Madsen DH, Engelholm LH, Behrendt N. The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review). International Journal of Oncology. 47: 1177-88. PMID 26316068 DOI: 10.3892/ijo.2015.3120  1
2015 Madsen DH, Bugge TH. The source of matrix-degrading enzymes in human cancer: Problems of research reproducibility and possible solutions. The Journal of Cell Biology. 209: 195-8. PMID 25918222 DOI: 10.1083/jcb.201501034  1
2015 Madsen DE, Sidelmann JJ, Biltoft D, Gram J, Hansen S. C1-inhibitor polymers activate the FXII-dependent kallikrein-kinin system: Implication for a role in hereditary angioedema. Biochimica Et Biophysica Acta. 1850: 1336-42. PMID 25800206 DOI: 10.1016/j.bbagen.2015.03.005  1
2015 Gram AS, Bladbjerg EM, Skov J, Ploug T, Sjödin A, Rosenkilde M, Madsen DE, Stallknecht BM. Three months of strictly controlled daily endurance exercise reduces thrombin generation and fibrinolytic risk markers in younger moderately overweight men. European Journal of Applied Physiology. 115: 1331-8. PMID 25618791 DOI: 10.1007/s00421-015-3106-z  0.01
2014 Madsen DE, Hansen S, Gram J, Bygum A, Drouet C, Sidelmann JJ. Presence of C1-inhibitor polymers in a subset of patients suffering from hereditary angioedema. Plos One. 9: e112051. PMID 25369003 DOI: 10.1371/journal.pone.0112051  1
2014 Madsen DH, Szabo R, Molinolo AA, Bugge TH. TMPRSS13 deficiency impairs stratum corneum formation and epidermal barrier acquisition. The Biochemical Journal. 461: 487-95. PMID 24832573 DOI: 10.1042/BJ20140337  1
2014 Ascic E, Ohm RG, Petersen R, Hansen MR, Hansen CL, Madsen D, Tanner D, Nielsen TE. Synthesis of oxacyclic scaffolds via dual ruthenium hydride/Brønsted acid-catalyzed isomerization/cyclization of allylic ethers. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 3297-300. PMID 24616060 DOI: 10.1002/Chem.201304270  1
2014 Jürgensen HJ, Johansson K, Madsen DH, Porse A, Melander MC, Sørensen KR, Nielsen C, Bugge TH, Behrendt N, Engelholm LH. Complex determinants in specific members of the mannose receptor family govern collagen endocytosis. The Journal of Biological Chemistry. 289: 7935-47. PMID 24500714 DOI: 10.1074/jbc.M113.512780  1
2013 Madsen DH, Bugge TH. Imaging collagen degradation in vivo highlights a key role for M2-polarized macrophages in extracellular matrix degradation. Oncoimmunology. 2: e27127. PMID 24498566 DOI: 10.4161/onci.27127  1
2013 Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS, Brenner DA, Burgdorf S, Engelholm LH, Behrendt N, Holmbeck K, Weigert R, et al. M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. The Journal of Cell Biology. 202: 951-66. PMID 24019537 DOI: 10.1083/Jcb.201301081  1
2013 Madsen DH, Jürgensen HJ, Ingvarsen S, Melander MC, Albrechtsen R, Hald A, Holmbeck K, Bugge TH, Behrendt N, Engelholm LH. Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis. Plos One. 8: e71261. PMID 23940733 DOI: 10.1371/journal.pone.0071261  1
2013 Madsen DE, Sidelmann JJ, Overgaard K, Koch C, Gram JB. ELISA for determination of total coagulation factor XII concentration in human plasma. Journal of Immunological Methods. 394: 32-9. PMID 23639297 DOI: 10.1016/j.jim.2013.04.012  1
2013 Ingvarsen S, Porse A, Erpicum C, Maertens L, Jürgensen HJ, Madsen DH, Melander MC, Gårdsvoll H, Høyer-Hansen G, Noel A, Holmbeck K, Engelholm LH, Behrendt N. Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis. The Journal of Biological Chemistry. 288: 10195-204. PMID 23413031 DOI: 10.1074/jbc.M112.447169  1
2012 Madsen DE, Ingerslev J, Sidelmann JJ, Thorn JJ, Gram J. Intraoperative blood loss during orthognathic surgery is predicted by thromboelastography. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. 70: e547-52. PMID 22990100 DOI: 10.1016/j.joms.2012.06.182  1
2012 Lund IK, Rasch MG, Ingvarsen S, Pass J, Madsen DH, Engelholm LH, Behrendt N, Høyer-Hansen G. Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo. Frontiers in Pharmacology. 3: 122. PMID 22754528 DOI: 10.3389/fphar.2012.00122  1
2012 Madsen DH, Jürgensen HJ, Ingvarsen S, Melander MC, Vainer B, Egerod KL, Hald A, Rønø B, Madsen CA, Bugge TH, Engelholm LH, Behrendt N. Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis. The Journal of Pathology. 227: 94-105. PMID 22294280 DOI: 10.1002/path.3981  1
2011 Jürgensen HJ, Madsen DH, Ingvarsen S, Melander MC, Gårdsvoll H, Patthy L, Engelholm LH, Behrendt N. A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180. The Journal of Biological Chemistry. 286: 32736-48. PMID 21768090 DOI: 10.1074/jbc.M111.266692  1
2011 Madsen DH, Ingvarsen S, Jürgensen HJ, Melander MC, Kjøller L, Moyer A, Honoré C, Madsen CA, Garred P, Burgdorf S, Bugge TH, Behrendt N, Engelholm LH. The non-phagocytic route of collagen uptake: a distinct degradation pathway. The Journal of Biological Chemistry. 286: 26996-7010. PMID 21652704 DOI: 10.1074/jbc.M110.208033  1
2009 Engelholm LH, Ingvarsen S, Jürgensen HJ, Hillig T, Madsen DH, Nielsen BS, Behrendt N. The collagen receptor uPARAP/Endo180. Frontiers in Bioscience (Landmark Edition). 14: 2103-14. PMID 19273187  1
2008 Ingvarsen S, Madsen DH, Hillig T, Lund LR, Holmbeck K, Behrendt N, Engelholm LH. Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells. Biological Chemistry. 389: 943-53. PMID 18627313 DOI: 10.1515/BC.2008.097  1
2008 Hillig T, Engelholm LH, Ingvarsen S, Madsen DH, Gårdsvoll H, Larsen JK, Ploug M, Danø K, Kjøller L, Behrendt N. A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor. The Journal of Biological Chemistry. 283: 15217-23. PMID 18362146 DOI: 10.1074/jbc.C700214200  1
2007 Madsen DH, Engelholm LH, Ingvarsen S, Hillig T, Wagenaar-Miller RA, Kjøller L, Gårdsvoll H, Høyer-Hansen G, Holmbeck K, Bugge TH, Behrendt N. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation. The Journal of Biological Chemistry. 282: 27037-45. PMID 17623673 DOI: 10.1074/jbc.M701088200  1
2007 Sulek J, Wagenaar-Miller RA, Shireman J, Molinolo A, Madsen DH, Engelholm LH, Behrendt N, Bugge TH. Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 347-53. PMID 17189524 DOI: 10.1369/jhc.6A7133.2006  1
2005 Goetz W, Bertelsen P, Binau CS, Gunnlaugsson HP, Hviid SF, Kinch KM, Madsen DE, Madsen MB, Olsen M, Gellert R, Klingelhöfer G, Ming DW, Morris RV, Rieder R, Rodionov DS, et al. Indication of drier periods on Mars from the chemistry and mineralogy of atmospheric dust Nature. 436: 62-65. PMID 16001062 DOI: 10.1038/nature03807  1
2004 Hemmingsen L, Madsen DE, Esbensen AL, Olsen L, Engelsen SB. Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations. Carbohydrate Research. 339: 937-48. PMID 15010301 DOI: 10.1016/j.carres.2003.11.024  0.01
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