John Michael Pezzuto - Publications

Affiliations: 
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy University of Illinois at Chicago, Chicago, IL, United States 

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Year Citation  Score
2020 Zaman KAU, Hu Z, Wu X, Hou S, Saito J, Kondratyuk TP, Pezzuto JM, Cao S. NF-κB Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from . Journal of Natural Products. PMID 32163285 DOI: 10.1021/Acs.Jnatprod.9B01190  0.438
2019 Park EJ, Sang-Ngern M, Chang LC, Pezzuto JM. Physalactone and 4β-Hydroxywithanolide E Isolated from Physalis peruviana Inhibit LPS-Induced Expression of COX-2 and iNOS Accompanied by Abatement of Akt and STAT1. Journal of Natural Products. PMID 30649869 DOI: 10.1021/Acs.Jnatprod.8B00861  0.356
2019 Hussain RA, Badshah A, Ahmed N, Pezzuto JM, Kondratyuk TP, Park E, Hussain I. Synthesis, characterization and biological applications of selenoureas having ferrocene and substituted benzoyl functionalities Polyhedron. 170: 12-24. DOI: 10.1016/J.Poly.2019.05.027  0.401
2018 Pezzuto JM. Resveratrol: Twenty Years of Growth, Development and Controversy. Biomolecules & Therapeutics. PMID 30332889 DOI: 10.4062/Biomolther.2018.176  0.359
2018 Zhang M, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis and Structure-Activity Relationships of Tetrahydro-β-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents. Anticancer Research. 38: 4425-4433. PMID 30061206 DOI: 10.21873/Anticanres.12744  0.343
2018 da Silva ES, Oliveira BG, Pereira ACH, Pimentel EF, Pezzuto JM, Lenz D, Kondratyuk TP, Andrade TU, Fronza M, Scherer R, Maia JF, Romão W, Alves FL, Ventura JA, Endringer DC. Induction of NAD (P)H: Quinone reductase 1 (QR1) and antioxidant activities in vitro of 'Toranja Burarama' (Citrus maxima [Burm.] Merr.). Phytotherapy Research : Ptr. PMID 29998488 DOI: 10.1002/Ptr.6149  0.352
2017 Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1. Bioorganic & Medicinal Chemistry Letters. PMID 29153737 DOI: 10.1016/J.Bmcl.2017.11.010  0.368
2017 Cai YS, Sarotti AM, Gündisch D, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities. Bioorganic & Medicinal Chemistry Letters. PMID 28927792 DOI: 10.1016/J.Bmcl.2017.09.021  0.433
2017 Li CS, Sarotti AM, Huang P, Dang UT, Hurdle JG, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. NF-κB inhibitors, unique γ-pyranol-γ-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462. Scientific Reports. 7: 10424. PMID 28874704 DOI: 10.1038/S41598-017-10537-1  0.419
2016 Chang LC, Sang-Ngern M, Pezzuto JM, Ma C. The Daniel K. Inouye College of Pharmacy Scripts: Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention Activities. Hawai'I Journal of Medicine & Public Health : a Journal of Asia Pacific Medicine & Public Health. 75: 353-359. PMID 27920947  0.372
2016 Youn UJ, Park EJ, Kondratyuk TP, Sripisut T, Laphookhieo S, Pezzuto JM, Leng CC. Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis. Fitoterapia. PMID 27575322 DOI: 10.1016/J.Fitote.2016.08.012  0.442
2016 Issa ME, Berndt S, Carpentier G, Pezzuto JM, Cuendet M. Bruceantin inhibits multiple myeloma cancer stem cell proliferation. Cancer Biology & Therapy. 0. PMID 27434731 DOI: 10.1080/15384047.2016.1210737  0.319
2016 Kondratyuk TP, Adrian JA, Wright B, Park EJ, van Breemen RB, Morris KR, Pezzuto JM. Evidence supporting the conceptual framework of cancer chemoprevention in canines. Scientific Reports. 6: 26500. PMID 27216246 DOI: 10.1038/Srep26500  0.302
2016 Sang-Ngern M, Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Wall MM, Ruf M, Lorch SE, Leong E, Pezzuto JM, Chang LC. Withanolides derived from Physalis peruviana (Poha) with potential anti-inflammatory activity. Bioorganic & Medicinal Chemistry Letters. PMID 27210437 DOI: 10.1016/J.Bmcl.2016.04.077  0.432
2016 Youn UJ, Park EJ, Kondratyuk TP, Sang-Ngern M, Wall MM, Wei Y, Pezzuto JM, Chang LC. Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates. Journal of Natural Products. PMID 27196335 DOI: 10.1021/Acs.Jnatprod.5B00970  0.431
2016 Fatima N, Kondratyuk TP, Park EJ, Marler LE, Jadoon M, Qazi MA, Mehboob Mirza H, Khan I, Atiq N, Chang LC, Ahmed S, Pezzuto JM. Endophytic fungi associated with Taxus fuana (West Himalayan Yew) of Pakistan: potential bio-resources for cancer chemopreventive agents. Pharmaceutical Biology. 1-8. PMID 27159021 DOI: 10.3109/13880209.2016.1170154  0.334
2016 Guan Y, Wang D, Tan GT, Van Hung N, Cuong NM, Pezzuto JM, Fong HH, Soejarto DD, Zhang H. Litsea Species as Potential Antiviral Plant Sources. The American Journal of Chinese Medicine. 44: 275-90. PMID 27080941 DOI: 10.1142/S0192415X16500166  0.372
2016 Park EJ, Sang-Ngern M, Chang LC, Pezzuto JM. Induction of cell cycle arrest and apoptosis with down-regulation of Hsp90 client proteins and histone modification by 4β-hydroxywithanolide E isolated from Physalis peruviana. Molecular Nutrition & Food Research. PMID 27006100 DOI: 10.1002/Mnfr.201500977  0.346
2016 Jafri L, Saleem S, Kondrytuk TP, Haq IU, Ullah N, Pezzuto JM, Mirza B. Hedera nepalensis K. Koch: A Novel Source of Natural Cancer Chemopreventive and Anticancerous Compounds. Phytotherapy Research : Ptr. 30: 447-53. PMID 26692176 DOI: 10.1002/Ptr.5546  0.409
2016 Amir MK, Zia-ur-Rehman Z, Hayat F, Khan SZ, Hogarth G, Kondratyuk T, Pezzuto J, Tahir MN. Monofunctional platinum(ii) dithiocarbamate complexes: synthesis, characterization and anticancer activity Rsc Advances. 6: 110517-110524. DOI: 10.1039/C6Ra19469A  0.308
2016 Khan SZ, Amir MK, Ullah I, Aamir A, Pezzuto JM, Kondratyuk T, Bélanger-Gariepy F, Ali A, Khan S, Zia-ur-Rehman. New heteroleptic palladium(II) dithiocarbamates: Synthesis, characterization, packing and anticancer activity against five different cancer cell lines Applied Organometallic Chemistry. DOI: 10.1002/Aoc.3445  0.335
2015 Cragg GM, Pezzuto JM. Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. PMID 26679767 DOI: 10.1159/000443404  0.361
2015 Youn UJ, Sripisut T, Park EJ, Kondratyuk TP, Fatima N, Simmons CJ, Wall MM, Sun D, Pezzuto JM, Chang LC. Determination of the absolute configuration of chaetoviridins and other bioactive azaphilones from the endophytic fungus Chaetomium globosum. Bioorganic & Medicinal Chemistry Letters. 25: 4719-23. PMID 26343828 DOI: 10.1016/J.Bmcl.2015.08.063  0.43
2015 Chelsky ZL, Yue P, Kondratyuk TP, Paladino D, Pezzuto JM, Cushman M, Turkson J. A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. Molecular Pharmacology. 88: 524-33. PMID 26138072 DOI: 10.1124/Mol.115.099093  0.317
2015 Hussain RA, Badshah A, Pezzuto JM, Ahmed N, Kondratyuk TP, Park EJ. Ferrocene incorporated selenoureas as anticancer agents. Journal of Photochemistry and Photobiology. B, Biology. 148: 197-208. PMID 25966308 DOI: 10.1016/J.Jphotobiol.2015.04.024  0.364
2015 Sang-ngern M, Youn U, Park E, Kondratyuk T, Miklossy G, Walla M, Simmons C, Turkson J, Pezzuto J, Chang L. Anticancer potential of withanolides and its derivatives from Physalis peruviana (POHA) Planta Medica. 81. DOI: 10.1055/S-0035-1556525  0.303
2014 Parrish SM, Yoshida WY, Kondratyuk TP, Park EJ, Pezzuto JM, Kelly M, Williams PG. Spongiapyridine and related spongians isolated from an Indonesian Spongia sp. Journal of Natural Products. 77: 1644-9. PMID 24992702 DOI: 10.1021/Np500256W  0.455
2014 García ME, Nicotra VE, Oberti JC, Ríos-Luci C, León LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padrón JM, Hueso-Falcón I, Estévez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. European Journal of Medicinal Chemistry. 82: 68-81. PMID 24878636 DOI: 10.1016/J.Ejmech.2014.05.045  0.451
2014 Chai X, Youn UJ, Sun D, Dai J, Williams P, Kondratyuk TP, Borris RP, Davies J, Villanueva IG, Pezzuto JM, Chang LC. Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10. Journal of Natural Products. 77: 227-33. PMID 24533857 DOI: 10.1021/Np4006635  0.38
2014 Pan W, Liu K, Guan Y, Tan GT, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS, Zhang H. Bioactive compounds from Vitex leptobotrys Journal of Natural Products. 77: 663-667. PMID 24404757 DOI: 10.1021/Np400779V  0.382
2014 Park EJ, Shen L, Sun D, Pezzuto JM. Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Natural Products. 77: 527-35. PMID 24299616 DOI: 10.1021/Np400800H  0.3
2014 Endringer DC, Taveira FSN, Kondratyuk TP, Pezzuto JM, Bragaa FC. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium Brazilian Journal of Pharmacognosy. 24: 408-412. DOI: 10.1016/J.Bjp.2014.08.002  0.322
2013 Pezzuto JM, Kondratyuk TP, Ogas T. Resveratrol derivatives: a patent review (2009 - 2012). Expert Opinion On Therapeutic Patents. 23: 1529-46. PMID 24032623 DOI: 10.1517/13543776.2013.834888  0.329
2013 Pansanit A, Park EJ, Kondratyuk TP, Pezzuto JM, Lirdprapamongkol K, Kittakoop P. Vermelhotin, an anti-inflammatory agent, suppresses nitric oxide production in RAW 264.7 cells via p38 inhibition. Journal of Natural Products. 76: 1824-7. PMID 24016057 DOI: 10.1021/Np400565E  0.307
2013 Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. European Journal of Medicinal Chemistry. 68: 412-21. PMID 23994869 DOI: 10.1016/J.Ejmech.2013.07.052  0.46
2013 Ogas T, Kondratyuk TP, Pezzuto JM. Resveratrol analogs: promising chemopreventive agents. Annals of the New York Academy of Sciences. 1290: 21-9. PMID 23855462 DOI: 10.1111/Nyas.12196  0.343
2013 Carlson S, Marler L, Nam SJ, Santarsiero BD, Pezzuto JM, Murphy BT. Potential chemopreventive activity of a new macrolide antibiotic from a marine-derived Micromonospora sp. Marine Drugs. 11: 1152-61. PMID 23552877 DOI: 10.3390/Md11041152  0.401
2013 Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M. Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. Journal of Medicinal Chemistry. 56: 2581-605. PMID 23472886 DOI: 10.1021/Jm400026K  0.33
2013 Ihsan-ul-Haq, Youn UJ, Chai X, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Mirza B, Pezzuto JM, Chang LC. Biologically active withanolides from Withania coagulans. Journal of Natural Products. 76: 22-8. PMID 23316950 DOI: 10.1021/Np300534X  0.459
2013 Haq IU, Mirza B, Kondratyuk TP, Park EJ, Burns BE, Marler LE, Pezzuto JM. Preliminary evaluation for cancer chemopreventive and cytotoxic potential of naturally growing ethnobotanically selected plants of Pakistan Pharmaceutical Biology. 51: 316-328. PMID 23137214 DOI: 10.3109/13880209.2012.728612  0.311
2013 Zong YY, Lowell K, Jiang P, Che CT, Pezzuto JM, Fong HH. Phenolic Constituents of Rhodiola coccinea, a Tibetan Folk Medicine1. Planta Medica. 57: 589. PMID 17226214 DOI: 10.1055/S-2006-960220  0.362
2012 Horgen FD, Madulid DA, Angerhofer CK, Pezzuto JM, Soejarto DD, Farnsworth NR. Isolation of gallic acid esters as antiplasmodial constituents of Swintonia foxworthyi (Anacardiaceae). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 4: 353-6. PMID 23195587 DOI: 10.1016/S0944-7113(97)80046-3  0.425
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1). Bioorganic & Medicinal Chemistry. 20: 7030-9. PMID 23142320 DOI: 10.1016/J.Bmc.2012.10.006  0.344
2012 Yu X, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors. Organic & Biomolecular Chemistry. 10: 8835-47. PMID 23044819 DOI: 10.1039/C2Ob26456K  0.34
2012 Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Tanamatayarat P, Wongwiwatthananukit S, Toyama O, Songsak T, Pezzuto JM, Chang LC. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorganic & Medicinal Chemistry Letters. 22: 5559-62. PMID 22850207 DOI: 10.1016/J.Bmcl.2012.07.010  0.459
2012 Luqman S, Meena A, Singh P, Kondratyuk TP, Marler LE, Pezzuto JM, Negi AS. Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents. Chemical Biology & Drug Design. 80: 616-24. PMID 22726671 DOI: 10.1111/J.1747-0285.2012.01439.X  0.438
2012 Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. Journal of Medicinal Chemistry. 55: 5965-81. PMID 22712432 DOI: 10.1021/Jm3006806  0.341
2012 Kondratyuk TP, Park EJ, Yu R, van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Marine Drugs. 10: 451-64. PMID 22412812 DOI: 10.3390/Md10020451  0.416
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. Bioorganic & Medicinal Chemistry. 20: 2427-34. PMID 22386564 DOI: 10.1016/J.Bmc.2012.01.047  0.333
2012 Park EJ, Pezzuto JM. Flavonoids in cancer prevention. Anti-Cancer Agents in Medicinal Chemistry. 12: 836-51. PMID 22292763 DOI: 10.2174/187152012802650075  0.353
2012 Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Xuan LT, Hiep NT, Hung NV, Loc PK, Dac LX, Bich TQ, Cuong NM, Ly HM, Zhang HJ, ... ... Pezzuto JM, et al. Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis. Pharmaceutical Biology. 50: 30-41. PMID 22196581 DOI: 10.3109/13880209.2011.634424  0.319
2012 Park EJ, Kiselev E, Conda-Sheridan M, Cushman M, Pezzuto JM. Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells. Journal of Natural Products. 75: 378-84. PMID 22148260 DOI: 10.1021/Np200791J  0.348
2012 Soejarto DD, Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Zhang HJ, Franzblau SG, Tan GT, Pezzuto JM, Riley MC, Elkington BG, Waller DP. An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development. Pharmaceutical Biology. 50: 42-60. PMID 22136442 DOI: 10.3109/13880209.2011.619700  0.315
2012 Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. Bioorganic & Medicinal Chemistry. 20: 510-20. PMID 22115839 DOI: 10.1016/J.Bmc.2011.09.031  0.329
2012 Park E, Pezzuto JM, Jang KH, Nam S, Bucarey SA, Fenical W. Suppression of nitric oxide synthase by thienodolin in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Natural Product Communications. 7: 789-794. DOI: 10.1177/1934578X1200700625  0.34
2012 Park E, Morrell A, Conda-Sheridan M, Cushman M, Pezzuto JM. Abstract 1934: Characterization of the anti-proliferative effect of 6-(3-aminopropyl)-9-methoxy-3-nitro-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione in cultured PC-3 cells Cancer Research. 72: 1934-1934. DOI: 10.1158/1538-7445.Am2012-1934  0.329
2012 Silva D, Bolzani V, Soares C, Pezzuto J, Morais M, Marler L, Luqman S, Kondratyuk T, Petronio M, Regasini L. Chemopreventive potential of natural products isolated from a alchornea glandulosa, pterogyne nitens and its semisynthetic analogs Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6923.1  0.479
2012 Bolzani V, Soares C, Pezzuto J, Luqman S, Morais M, Kondratyuk T, Petronio M, Regasini L, Silva D. Suppression of TNF-α induced NFκB activity by gallic acid and its semi-synthetic alkyl-gallates: Possible role in cancer chemoprevention Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6922.1  0.413
2012 Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Inhibiton of NFκB activation and aromatase activity by vanilloids: An in vitro and in silico study Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6913.1  0.445
2012 Luqman S, Kondratyuk TP, Hosino J, Cushman M, Pezzuto JM. Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by resveratrol derivatives Nature Precedings. 7: 1-1. DOI: 10.1038/Npre.2012.6908.1  0.349
2011 Park EJ, Cheenpracha S, Chang LC, Pezzuto JM. Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated RAW 264.7 cells. Phytochemistry Letters. 4: 426-431. PMID 22180763 DOI: 10.1016/J.Phytol.2011.07.009  0.339
2011 Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorganic & Medicinal Chemistry. 19: 6182-95. PMID 21978950 DOI: 10.1016/J.Bmc.2011.09.020  0.422
2011 Park EJ, Cheenpracha S, Chang LC, Kondratyuk TP, Pezzuto JM. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera. Nutrition and Cancer. 63: 971-82. PMID 21774591 DOI: 10.1080/01635581.2011.589960  0.353
2011 Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, et al. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. Plos One. 6: e19881. PMID 21698226 DOI: 10.1371/Journal.Pone.0019881  0.306
2011 Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-α-induced nuclear factor κB activation and aromatase activity by capsaicin and its analog capsazepine. Journal of Medicinal Food. 14: 1344-51. PMID 21663483 DOI: 10.1089/Jmf.2010.0236  0.404
2011 Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 592-607. PMID 21464033 DOI: 10.1158/1940-6207.Capr-10-0004  0.359
2011 Zou J, Pan L, Li Q, Zhao J, Pu J, Yao P, Gong N, Lu Y, Kondratyuk TP, Pezzuto JM, Fong HH, Zhang H, Sun H. Rubesanolides A and B: diterpenoids from Isodon rubescens. Organic Letters. 13: 1406-9. PMID 21332131 DOI: 10.1021/Ol200086K  0.353
2011 Pezzuto JM. The phenomenon of resveratrol: redefining the virtues of promiscuity. Annals of the New York Academy of Sciences. 1215: 123-30. PMID 21261650 DOI: 10.1111/J.1749-6632.2010.05849.X  0.415
2011 Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, et al. Bioactive compounds from the fern Lepisorus contortus. Journal of Natural Products. 74: 129-36. PMID 21261296 DOI: 10.1021/Np100373F  0.466
2011 Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Analytical Chemistry. 83: 1048-52. PMID 21192729 DOI: 10.1021/Ac1028424  0.344
2010 Marler L, Conda-Sheridan M, Cinelli MA, Morrell AE, Cushman M, Chen L, Huang K, Van Breemen R, Pezzuto JM. Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives. Anticancer Research. 30: 4873-82. PMID 21187465  0.305
2010 Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284. Journal of Medicinal Chemistry. 53: 8688-99. PMID 21105712 DOI: 10.1021/Jm1011066  0.407
2010 Gullett NP, Ruhul Amin AR, Bayraktar S, Pezzuto JM, Shin DM, Khuri FR, Aggarwal BB, Surh YJ, Kucuk O. Cancer prevention with natural compounds. Seminars in Oncology. 37: 258-81. PMID 20709209 DOI: 10.1053/J.Seminoncol.2010.06.014  0.375
2010 Cheenpracha S, Park EJ, Yoshida WY, Barit C, Wall M, Pezzuto JM, Chang LC. Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits. Bioorganic & Medicinal Chemistry. 18: 6598-602. PMID 20685125 DOI: 10.1016/J.Bmc.2010.03.057  0.442
2010 Luqman S, Pezzuto JM. NFkappaB: a promising target for natural products in cancer chemoprevention. Phytotherapy Research : Ptr. 24: 949-63. PMID 20577970 DOI: 10.1002/Ptr.3171  0.352
2010 Sun B, Hoshino J, Jermihov K, Marler L, Pezzuto JM, Mesecar AD, Cushman M. Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorganic & Medicinal Chemistry. 18: 5352-66. PMID 20558073 DOI: 10.1016/J.Bmc.2010.05.042  0.412
2010 Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. Journal of Medicinal Chemistry. 53: 5033-43. PMID 20527891 DOI: 10.1021/Jm100274C  0.391
2010 Nam SJ, Gaudêncio SP, Kauffman CA, Jensen PR, Kondratyuk TP, Marler LE, Pezzuto JM, Fenical W. Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis. Journal of Natural Products. 73: 1080-6. PMID 20481500 DOI: 10.1021/Np100087C  0.41
2010 Calamini B, Ratia K, Malkowski MG, Cuendet M, Pezzuto JM, Santarsiero BD, Mesecar AD. Pleiotropic mechanisms facilitated by resveratrol and its metabolites. The Biochemical Journal. 429: 273-82. PMID 20450491 DOI: 10.1042/Bj20091857  0.351
2010 Cheenpracha S, Park EJ, Rostama B, Pezzuto JM, Chang LC. Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide, epimuqubilin A. Marine Drugs. 8: 429-37. PMID 20411107 DOI: 10.3390/Md8030429  0.436
2010 Morais MC, Luqman S, Kondratyuk TP, Petronio MS, Regasini LO, Silva DH, Bolzani VS, Soares CP, Pezzuto JM. Suppression of TNF-α induced NFκB activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Natural Product Research. 24: 1758-65. PMID 20408045 DOI: 10.1080/14786410903335232  0.432
2010 Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, et al. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 71: 641-7. PMID 20100622 DOI: 10.1016/J.Phytochem.2010.01.002  0.4
2010 Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prevention Research (Philadelphia, Pa.). 3: 221-32. PMID 20068129 DOI: 10.1158/1940-6207.Capr-09-0049  0.321
2010 Endringer DC, Valadares YM, Campana PR, Campos JJ, Guimarães KG, Pezzuto JM, Braga FC. Evaluation of Brazilian plants on cancer chemoprevention targets in vitro. Phytotherapy Research : Ptr. 24: 928-33. PMID 19957245 DOI: 10.1002/Ptr.3050  0.406
2010 Park E, Kondratyuk T, Morrell A, Kiselev E, Cushman M, Pezzuto J. Abstract B91: Induction of RXR transcriptional activity and consequent upregulation of p21 by 3‐amino‐6‐(3‐aminopropyl)‐5,6‐dihydro‐5, 11‐dioxo‐11H‐indeno[1,2‐c]isoquinoline dihydrochloride in MCF‐7 breast cancer cells Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-B91  0.359
2010 Marler LE, Cushman M, Sun B, Mesecar AD, Jermihov K, Breemen RBv, Pezzuto JM. Abstract A68: Aromatase inhibition and chemopreventive potential of novel resveratrol derivatives Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-A68  0.417
2009 Balunas MJ, Su B, Riswan S, Fong HH, Brueggemeier RW, Pezzuto JM, Kinghorn AD. Isolation and Characterization of Aromatase Inhibitors from Brassaiopsis glomerulata (Araliaceae). Phytochemistry Letters. 2: 29-33. PMID 20161072 DOI: 10.1016/J.Phytol.2008.10.009  0.443
2009 Schupp PJ, Kohlert-Schupp C, Whitefield S, Engemann A, Rohde S, Hemscheidt T, Pezzuto JM, Kondratyuk TP, Park EJ, Marler L, Rostama B, Wright AD. Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Natural Product Communications. 4: 1717-28. PMID 20120114 DOI: 10.1177/1934578X0900401222  0.386
2009 Endringer DC, Pezzuto JM, Braga FC. NF-kappaB inhibitory activity of cyclitols isolated from Hancornia speciosa. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 16: 1064-9. PMID 19423310 DOI: 10.1016/J.Phymed.2009.03.022  0.434
2009 Deng Y, Balunas MJ, Kim JA, Lantvit DD, Chin YW, Chai H, Sugiarso S, Kardono LB, Fong HH, Pezzuto JM, Swanson SM, de Blanco EJ, Kinghorn AD. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. Journal of Natural Products. 72: 1165-9. PMID 19422206 DOI: 10.1021/Np9001724  0.448
2009 Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities. Journal of Medicinal Chemistry. 52: 1873-84. PMID 19265439 DOI: 10.1021/Jm801335Z  0.403
2009 Yao G, Kondratyuk TP, Tan GT, Pezzuto JM, Chang LC. Bioactive sulfated sesterterpene alkaloids and sesterterpene sulfates from the marine sponge Fasciospongia sp. Journal of Natural Products. 72: 319-23. PMID 19178162 DOI: 10.1021/Np8005343  0.451
2009 Mi Q, Pezzuto JM, Farnsworth NR, Wani MC, Kinghorn AD, Swanson SM. Use of the in vivo hollow fiber assay in natural products anticancer drug discovery. Journal of Natural Products. 72: 573-80. PMID 19161316 DOI: 10.1021/Np800767A  0.363
2009 Asolkar RN, Freel KC, Jensen PR, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. Journal of Natural Products. 72: 396-402. PMID 19117399 DOI: 10.1021/Np800617A  0.437
2009 Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorganic & Medicinal Chemistry. 17: 1044-54. PMID 18487053 DOI: 10.1016/J.Bmc.2008.04.031  0.334
2009 Ghufran MA, Qureshi RA, Batool A, Kondratyuk TP, Guilford JM, Marler LE, Chang LC, Pezzuto JM. Evaluation of selected indigenous medicinal plants from the western Himalayas for cytotoxicity and as potential cancer chemopreventive agents Pharmaceutical Biology. 47: 533-538. DOI: 10.1080/13880200902873847  0.41
2008 Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2104-12. PMID 18653743 DOI: 10.1124/Dmd.108.021857  0.313
2008 Endringer DC, Guimarães KG, Kondratyuk TP, Pezzuto JM, Braga FC. Selective inhibition of aromatase by a dihydroisocoumarin from Xyris pterygoblephara. Journal of Natural Products. 71: 1082-4. PMID 18462007 DOI: 10.1021/Np800098F  0.359
2008 Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 461-8. PMID 18006650 DOI: 10.1124/Dmd.107.018721  0.331
2008 Pezzuto J, Morris K. Abstract PL05-03: Influence of Mother Nature’s pharmacopeia on everyday health and wellbeing Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Pl05-03  0.357
2008 Pezzuto JM. Resveratrol as an inhibitor of carcinogenesis Pharmaceutical Biology. 46: 443-573. DOI: 10.1080/13880200802116610  0.355
2008 Topcu G, Turkmen Z, Schilling JK, Kingston DGI, Pezzuto JM, Ulubelen A. Cytotoxic activity of some Anatolian Salvia extracts and isolated abietane diterpenoids Pharmaceutical Biology. 46: 180-184. DOI: 10.1080/13880200701735411  0.412
2008 Cuendet M, Oteham CP, Moon RC, Keller WJ, Peaden PA, Pezzuto JM. Dietary administration of Asimina triloba (paw paw) extract increases tumor latency in N-methyl-N-nitrosourea-treated rats Pharmaceutical Biology. 46: 3-7. DOI: 10.1080/13880200701729497  0.306
2007 Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutrition and Cancer. 57: 28-37. PMID 17516860 DOI: 10.1080/01635580701268097  0.341
2007 Maiti A, Cuendet M, Croy VL, Endringer DC, Pezzuto JM, Cushman M. Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer. Journal of Medicinal Chemistry. 50: 2799-806. PMID 17511439 DOI: 10.1021/Jm070109I  0.324
2007 Williams PG, Asolkar RN, Kondratyuk T, Pezzuto JM, Jensen PR, Fenical W. Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola. Journal of Natural Products. 70: 83-8. PMID 17253854 DOI: 10.1021/Np0604580  0.39
2007 Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. Journal of Medicinal Chemistry. 50: 350-5. PMID 17228877 DOI: 10.1021/Jm060915+  0.402
2007 Jutiviboonsuk A, Zhang HJ, Kondratyuk TP, Herunsalee A, Chaukul W, Pezzuto JM, Fong HHS, Bunyapraphatsara N. Isolation and characterization of cancer chemopreventive compounds from Barringtonia maunwongyathiae Pharmaceutical Biology. 45: 185-194. DOI: 10.1080/13880200701213062  0.408
2006 Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. The Febs Journal. 273: 5714-23. PMID 17212786 DOI: 10.1111/J.1742-4658.2006.05560.X  0.392
2006 Thole JM, Kraft TF, Sueiro LA, Kang YH, Gills JJ, Cuendet M, Pezzuto JM, Seigler DS, Lila MA. A comparative evaluation of the anticancer properties of European and American elderberry fruits. Journal of Medicinal Food. 9: 498-504. PMID 17201636 DOI: 10.1089/Jmf.2006.9.498  0.395
2006 Balunas MJ, Jones WP, Chin YW, Mi Q, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Chai HB, Kinghorn AD. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chemistry & Biodiversity. 3: 897-915. PMID 17193321 DOI: 10.1002/Cbdv.200690092  0.402
2006 Wright AD, de Nys R, Angerhofer CK, Pezzuto JM, Gurrath M. Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products. Journal of Natural Products. 69: 1180-7. PMID 16933872 DOI: 10.1021/Np050510C  0.416
2006 He ZD, Ma CY, Tan GT, Sydara K, Tamez P, Southavong B, Bouamanivong S, Soejarto DD, Pezzuto JM, Fong HH, Zhang HJ. Rourinoside and rouremin, antimalarial constituents from Rourea minor. Phytochemistry. 67: 1378-84. PMID 16762381 DOI: 10.1016/J.Phytochem.2006.04.012  0.395
2006 Carcache-Blanco EJ, Cuendet M, Park EJ, Su BN, Rivero-Cruz JF, Farnsworth NR, Pezzuto JM, Douglas Kinghorn A. Potential cancer chemopreventive agents from Arbutus unedo. Natural Product Research. 20: 327-34. PMID 16644527 DOI: 10.1080/14786410500161205  0.484
2006 Cuendet M, Oteham CP, Moon RC, Pezzuto JM. Quinone reductase induction as a biomarker for cancer chemoprevention. Journal of Natural Products. 69: 460-3. PMID 16562858 DOI: 10.1021/Np050362Q  0.413
2006 Homhual S, Bunyapraphatsara N, Kondratyuk T, Herunsalee A, Chaukul W, Pezzuto JM, Fong HHS, Zhang HJ. Bioactive dammarane triterpenes from the mangrove Plant Bruguiera gymnorrhiza Journal of Natural Products. 69: 421-424. PMID 16562850 DOI: 10.1021/Np058112X  0.429
2006 Fang L, Ito A, Chai HB, Mi Q, Jones WP, Madulid DR, Oliveros MB, Gao Q, Orjala J, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Kinghorn AD. Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines. Journal of Natural Products. 69: 332-7. PMID 16562829 DOI: 10.1021/Np058083Q  0.465
2006 Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Medica. 72: 255-60. PMID 16534731 DOI: 10.1055/S-2005-873171  0.455
2006 Jang DS, Su BN, Pawlus AD, Kang YH, Kardono LB, Riswan S, Afriastini JJ, Fong HH, Pezzuto JM, Kinghorn AD. Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana. Phytochemistry. 67: 1832-7. PMID 16426647 DOI: 10.1016/J.Phytochem.2005.11.026  0.456
2006 Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. Journal of Medicinal Chemistry. 49: 693-708. PMID 16420055 DOI: 10.1021/Jm0509492  0.458
2006 Gills JJ, Jeffery EH, Matusheski NV, Moon RC, Lantvit DD, Pezzuto JM. Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion. Cancer Letters. 236: 72-9. PMID 15993536 DOI: 10.1016/J.Canlet.2005.05.007  0.322
2006 Kraft TFB, Schmidt BM, Yousef G, Knight CT, Cuendet M, Kang Y, Pezzuto JM, Seigler DS, Lila MA. Chemopreventive Potential of Wild Lowbush Blueberry Fruits in Multiple Stages of Carcinogenesis Journal of Food Science. 70: S159-S166. DOI: 10.1111/J.1365-2621.2005.Tb07151.X  0.389
2005 He ZD, Ma CY, Zhang HJ, Tan GT, Tamez P, Sydara K, Bouamanivong S, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial constituents from Nauclea orientalis (L.) L. Chemistry & Biodiversity. 2: 1378-86. PMID 17191939 DOI: 10.1002/Cbdv.200590110  0.321
2005 Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. Analytical Chemistry. 77: 6407-14. PMID 16194107 DOI: 10.1021/Ac050892R  0.395
2005 Jones WP, Lobo-Echeverri T, Mi Q, Chai H, Lee D, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. The Journal of Pharmacy and Pharmacology. 57: 1101-8. PMID 16105231 DOI: 10.1211/Jpp.57.9.0005  0.446
2005 Gills JJ, Kosmeder J, Moon RC, Lantvit DD, Pezzuto JM. Effect of deguelin on UVB-induced skin carcinogenesis. Journal of Chemotherapy (Florence, Italy). 17: 297-301. PMID 16041863 DOI: 10.1179/Joc.2005.17.3.297  0.339
2005 Jang DS, Su BN, Pawlus AD, Jones WP, Kleps RA, Bunyapraphatsara N, Fong HH, Pezzuto JM, Kinghorn AD. Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi. Journal of Natural Products. 68: 1134-6. PMID 16038568 DOI: 10.1021/Np050132B  0.348
2005 Chow AW, Murillo G, Yu C, Van Breemen RB, Boddie AW, Pezzuto JM, Das Gupta TK, Mehta RG. Resveratrol inhibits rhabdomyosarcoma cell proliferation European Journal of Cancer Prevention. 14: 351-356. PMID 16030425 DOI: 10.1097/00008469-200508000-00007  0.359
2005 Zhang HJ, Nguyen VH, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata. Planta Medica. 71: 452-7. PMID 15931585 DOI: 10.1055/S-2005-864142  0.388
2005 Koch A, Tamez P, Pezzuto J, Soejarto D. Evaluation of plants used for antimalarial treatment by the Maasai of Kenya Journal of Ethnopharmacology. 101: 95-99. PMID 15878245 DOI: 10.1016/J.Jep.2005.03.011  0.334
2005 Rivero-Cruz JF, Lezutekong R, Lobo-Echeverri T, Ito A, Mi Q, Chai HB, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Morelli I, Kinghorn AD. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida. Phytotherapy Research : Ptr. 19: 136-40. PMID 15852485 DOI: 10.1002/Ptr.1642  0.413
2005 Lobo-Echeverri T, Rivero-Cruz JF, Su BN, Chai HB, Cordell GA, Pezzuto JM, Swanson SM, Soejarto DD, Kinghorn AD. Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida. Journal of Natural Products. 68: 577-80. PMID 15844953 DOI: 10.1021/Np0496688  0.406
2005 Tamez PA, Lantvit D, Lim E, Pezzuto JM. Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum. Journal of Ethnopharmacology. 98: 137-42. PMID 15763374 DOI: 10.1016/J.Jep.2005.01.015  0.331
2004 Su BN, Jones WP, Cuendet M, Kardono LB, Ismail R, Riswan S, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemistry. 65: 2861-6. PMID 15501253 DOI: 10.1016/J.Phytochem.2004.08.007  0.422
2004 Gafner S, Lee SK, Cuendet M, Barthélémy S, Vergnes L, Labidalle S, Mehta RG, Boone CW, Pezzuto JM. Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems Phytochemistry. 65: 2849-2859. PMID 15501252 DOI: 10.1016/J.Phytochem.2004.08.008  0.396
2004 Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2 Planta Medica. 70: 893-896. PMID 15490314 DOI: 10.1055/S-2004-832612  0.385
2004 Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, Gu JQ, Carcache-Blanco EJ, Pawlus AD, Lee SK, Park EJ, Cuendet M, Gills JJ, Bhat K, Park HS, Mata-Greenwood E, ... ... Pezzuto JM, et al. Natural inhibitors of carcinogenesis. Planta Medica. 70: 691-705. PMID 15326546 DOI: 10.1055/S-2004-827198  0.489
2004 Li Y, Grubjesic S, Nikolic D, Zhu D, Kosmeder JW, Moriarty RM, Pezzuto JM, Van Breemen RB. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 535-47. PMID 15277014 DOI: 10.1080/00498250410001713159  0.345
2004 Gu JQ, Graf TN, Lee D, Chai HB, Mi Q, Kardono LB, Setyowati FM, Ismail R, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kroll DJ, Falkinham JO, et al. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of Natural Products. 67: 1156-61. PMID 15270571 DOI: 10.1021/Np040027M  0.412
2004 Nguyen QC, Nguyen VH, Santarsiero BD, Mesecar AD, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. New 3-O-acyl betulinic acids from Strychnos vanprukii Craib. Journal of Natural Products. 67: 994-8. PMID 15217281 DOI: 10.1021/Np030469I  0.345
2004 Hwang BY, Su BN, Chai H, Mi Q, Kardono LB, Afriastini JJ, Riswan S, Santarsiero BD, Mesecar AD, Wild R, Fairchild CR, Vite GD, Rose WC, Farnsworth NR, Cordell GA, ... Pezzuto JM, et al. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. The Journal of Organic Chemistry. 69: 3350-8. PMID 15132542 DOI: 10.1021/Jo040120F  0.405
2004 Jang DS, Cuendet M, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of Asparagus officinalis Evaluated for Inhibitory Activity against Cyclooxygenase-2 Journal of Agricultural and Food Chemistry. 52: 2218-2222. PMID 15080623 DOI: 10.1021/Jf0305229  0.441
2004 Kang YH, Pezzuto JM. Induction of Quinone Reductase as a Primary Screen for Natural Product Anticarcinogens Methods in Enzymology. 382: 380-414. PMID 15047113 DOI: 10.1016/S0076-6879(04)82021-4  0.367
2004 Diaz F, Chai HB, Mi Q, Su BN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru. Journal of Natural Products. 67: 352-6. PMID 15043409 DOI: 10.1021/Np030479J  0.45
2004 Rivero-Cruz JF, Chai HB, Kardono LB, Setyowati FM, Afriatini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa. Journal of Natural Products. 67: 343-7. PMID 15043407 DOI: 10.1021/Np0304417  0.437
2004 Jang DS, Park EJ, Kang YH, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase. Archives of Pharmacal Research. 27: 169-72. PMID 15022717 DOI: 10.1007/Bf02980101  0.472
2004 Cuendet M, Gills JJ, Pezzuto JM. Brusatol-induced HL-60 cell differentiation involves NF-κB activation Cancer Letters. 206: 43-50. PMID 15019158 DOI: 10.1016/J.Canlet.2003.11.011  0.319
2004 Cuendet M, Pezzuto JM. Antitumor Activity of Bruceantin: An Old Drug with New Promise Journal of Natural Products. 67: 269-272. PMID 14987068 DOI: 10.1021/Np030304+  0.34
2004 Ito A, Chai HB, Kardono LB, Setowati FM, Afriastini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Saponins from the bark of Nephelium maingayi. Journal of Natural Products. 67: 201-5. PMID 14987059 DOI: 10.1021/Np030389E  0.465
2004 Zhang HJ, Sydara K, Tan GT, Ma C, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Bioactive constituents from Asparagus cochinchinensis. Journal of Natural Products. 67: 194-200. PMID 14987058 DOI: 10.1021/Np030370B  0.439
2004 Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 11: 18-23. PMID 14974442 DOI: 10.1078/0944-7113-00331  0.364
2004 Jang DS, Cuendet M, Pawlus AD, Kardono LB, Kawanishi K, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. Phytochemistry. 65: 345-50. PMID 14751306 DOI: 10.1016/J.Phytochem.2003.10.026  0.368
2004 Su B, Gu J, Kang Y, Park E, Pezzuto J, Kinghorn A. Induction of the Phase II Enzyme, Quinone Reductase, by Withanolides and Norwithanolides from Solanaceous Species Mini-Reviews in Organic Chemistry. 1: 115-123. DOI: 10.2174/1570193043488926  0.358
2004 Kondratyuk TP, Pezzuto JM. Natural product polyphenols of relevance to human health Pharmaceutical Biology. 42: 46-63. DOI: 10.1080/13880200490893519  0.362
2003 Topcu G, Aydogmus Z, Imre S, Gören AC, Pezzuto JM, Clement JA, Kingston DG. Brominated sesquiterpenes from the red alga Laurencia obtusa. Journal of Natural Products. 66: 1505-8. PMID 14640529 DOI: 10.1021/Np030176P  0.424
2003 Carcache-Blanco EJ, Kang YH, Park EJ, Su BN, Kardono LBS, Riswan S, Fong HHS, Pezzuto JM, Kinghorn AD. Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase Journal of Natural Products. 66: 1197-1202. PMID 14510596 DOI: 10.1021/Np030207G  0.467
2003 Jang DS, Park EJ, Kang YH, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria. Journal of Natural Products. 66: 1166-70. PMID 14510590 DOI: 10.1021/Np0302100  0.462
2003 Jang DS, Park EJ, Kang YH, Su BN, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model. Archives of Pharmacal Research. 26: 585-90. PMID 12967190 DOI: 10.1007/Bf02976704  0.457
2003 Su BN, Kang YH, Pinos RE, Santarsiero BD, Mesecar AD, Soejarto DD, Fong HH, Pezzuto JM, Kinghorn AD. Isolation and absolute stereochemistry of coussaric acid, a new bioactive triterpenoid from the stems of Coussarea brevicaulis. Phytochemistry. 64: 293-302. PMID 12946428 DOI: 10.1016/S0031-9422(03)00268-1  0.397
2003 Lee KH, Chai HB, Tamez PA, Pezzuto JM, Cordell GA, Win KK, Tin-Wa M. Biologically active alkylated coumarins from Kayea assamica. Phytochemistry. 64: 535-41. PMID 12943771 DOI: 10.1016/S0031-9422(03)00243-7  0.419
2003 Su BN, Park EJ, Nikolic D, Schunke Vigo J, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of Natural Products. 66: 1089-93. PMID 12932130 DOI: 10.1021/Np030081N  0.423
2003 Díaz F, Chávez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. Journal of Natural Products. 66: 865-7. PMID 12828478 DOI: 10.1021/Np0300784  0.456
2003 Topcu G, Altiner EN, Gozcu S, Halfon B, Aydogmus Z, Pezzuto JM, Zhou BN, Kingston DGI. Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity Planta Medica. 69: 464-467. PMID 12802732 DOI: 10.1055/S-2003-39705  0.44
2003 Zhang HJ, Tan GT, Santarsiero BD, Mesecar AD, Hung NV, Cuong NM, Doel Soejarto D, Pezzuto JM, Fong HH. New Sesquiterpenes from Litsea verticillata. Journal of Natural Products. 66: 609-15. PMID 12762792 DOI: 10.1021/Np020508A  0.347
2003 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean). Journal of Natural Products. 66: 583-7. PMID 12762787 DOI: 10.1021/Np020522N  0.473
2003 Fang L, Chai HB, Castillo JJ, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Brachistus stramoniifolius. Phytotherapy Research : Ptr. 17: 520-3. PMID 12748990 DOI: 10.1002/Ptr.1315  0.473
2003 Su BN, Jung Park E, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry. 63: 335-41. PMID 12737982 DOI: 10.1016/S0031-9422(03)00112-2  0.456
2003 Gu JQ, Li W, Kang YH, Su BN, Fong HHS, Van Breemen RB, Pezzuto JM, Kinghorn AD. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts Chemical and Pharmaceutical Bulletin. 51: 530-539. PMID 12736452 DOI: 10.1248/Cpb.51.530  0.346
2003 Gafner S, Bergeron C, Batcha LL, Reich J, Arnason JT, Burdette JE, Pezzuto JM, Angerhofer CK. Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. Journal of Natural Products. 66: 535-7. PMID 12713409 DOI: 10.1021/Np0205102  0.339
2003 Seo EK, Lee D, Shin YG, Chai HB, Navarro HA, Kardono LB, Rahman I, Cordell GA, Farnsworth NR, Pezzuto JM, Kinghorn AD, Wani MC, Wall ME. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Archives of Pharmacal Research. 26: 124-7. PMID 12643587 DOI: 10.1007/Bf02976656  0.386
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/Jo020542U  0.476
2003 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea. Journal of Natural Products. 66: 263-8. PMID 12608862 DOI: 10.1021/Np020379Y  0.38
2003 Chun KH, Kosmeder JW, Sun S, Pezzuto JM, Lotan R, Hong WK, Lee HY. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. Journal of the National Cancer Institute. 95: 291-302. PMID 12591985 DOI: 10.1093/Jnci/95.4.291  0.309
2003 Omar S, Zhang J, MacKinnon S, Leaman D, Durst T, Philogene BJ, Arnason JT, Sanchez-Vindas PE, Poveda L, Tamez PA, Pezzuto JM. Traditionally-used antimalarials from the Meliaceae. Current Topics in Medicinal Chemistry. 3: 133-9. PMID 12570769 DOI: 10.2174/1568026033392499  0.38
2003 Yu C, Shin YG, Kosmeder JW, Pezzuto JM, van Breemen RB. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Communications in Mass Spectrometry : Rcm. 17: 307-13. PMID 12569440 DOI: 10.1002/Rcm.918  0.32
2003 Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Reviews. 21: 231-55. PMID 12549763 DOI: 10.1023/A:1021254725842  0.37
2003 Duncan CJ, Cuendet M, Fronczek FR, Pezzuto JM, Mehta RG, Hamann MT, Ross SA. Chemical and biological investigation of the fungus Pulveroboletus ravenelii. Journal of Natural Products. 66: 103-7. PMID 12542354 DOI: 10.1021/Np0203990  0.417
2003 Hwang BY, Chai HB, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic triterpenes from the twigs of Celtis philippinensis. Phytochemistry. 62: 197-201. PMID 12482456 DOI: 10.1016/S0031-9422(02)00520-4  0.339
2003 Murillo G, Salti GI, Kosmeder JW, Pezzuto JM, Mehta RG. Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. European Journal of Cancer (Oxford, England : 1990). 38: 2446-54. PMID 12460790 DOI: 10.1016/S0959-8049(02)00192-2  0.334
2003 Verotta L, Guerrini M, El-Sebakhy NA, Assad AM, Toaima SM, Radwan MM, Luo YD, Pezzuto JM. Cycloartane and oleanane saponins from egyptian astragalus spp. as modulators of lymphocyte proliferation. Planta Medica. 68: 986-94. PMID 12451488 DOI: 10.1055/S-2002-35654  0.416
2003 Kinghorn AD, Su BN, Lee D, Gu JQ, Pezzuto JM. Cancer chemopreventive agents discovered by activity-guided fractionation: An update Current Organic Chemistry. 7: 213-226. DOI: 10.2174/1385272033373003  0.448
2003 Villinski JR, Dumas ER, Chai HB, Pezzuto JM, Angerhofer CK, Gafner S. Antibacterial activity and alkaloid content of Berberis thunbergii, Berberis vulgaris and Hydrastis canadensis Pharmaceutical Biology. 41: 551-557. DOI: 10.1080/13880200390500768  0.318
2003 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS. Natural anti-HIV agents. Part 3: Litseaverticillols A-H, novel sesquiterpenes from Litsea verticillata Tetrahedron. 59: 141-148. DOI: 10.1016/S0040-4020(02)01491-6  0.407
2003 Su BN, Cuendet M, Nikolic D, Kristinsson H, Ingólfsdóttir K, Van Breemen RB, Fong HHS, Pezzuto JM, Kinghorn AD. NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative from Cladonia furcata Magnetic Resonance in Chemistry. 41: 391-394. DOI: 10.1002/Mrc.1181  0.306
2002 Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, Lee YS, Hirschelman WH, Pezzuto JM, Mehta RG, van Breemen RB. Human, rat, and mouse metabolism of resveratrol. Pharmaceutical Research. 19: 1907-14. PMID 12523673 DOI: 10.1023/A:1021414129280  0.336
2002 Calderón AI, Terreaux C, Schenk K, Pattison P, Burdette JE, Pezzuto JM, Gupta MP, Hostettmann K. Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis. Journal of Natural Products. 65: 1749-53. PMID 12502307 DOI: 10.1021/Np0201164  0.355
2002 Su BN, Cuendet M, Farnsworth NR, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay. Planta Medica. 68: 1125-8. PMID 12494342 DOI: 10.1055/S-2002-36354  0.354
2002 Zhang HJ, Tamez PA, Aydogmus Z, Tan GT, Saikawa Y, Hashimoto K, Nakata M, Hung NV, Xuan le T, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva. Planta Medica. 68: 1088-91. PMID 12494335 DOI: 10.1055/S-2002-36350  0.337
2002 Jang DS, Cuendet M, Hawthorne ME, Kardono LBS, Kawanishi K, Fonga HHS, Mehta RG, Pezzuto JM, Kinghorn AD. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2 Phytochemistry. 61: 867-872. PMID 12453581 DOI: 10.1016/S0031-9422(02)00378-3  0.471
2002 Gu JQ, Park EJ, Vigo JS, Graham JG, Fong HH, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase. Journal of Natural Products. 65: 1616-20. PMID 12444686 DOI: 10.1021/Np020249P  0.442
2002 Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. Journal of Agricultural and Food Chemistry. 50: 7022-8. PMID 12428954 DOI: 10.1021/Jf020725H  0.353
2002 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. Journal of Agricultural and Food Chemistry. 50: 6330-4. PMID 12381112 DOI: 10.1021/Jf0206670  0.423
2002 Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Current Oncology Reports. 4: 478-86. PMID 12354359 DOI: 10.1007/S11912-002-0059-2  0.39
2002 Su BN, Park EJ, Mbwambo ZH, Santarsiero BD, Mesecar AD, Fong HH, Pezzuto JM, Kinghorn AD. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. Journal of Natural Products. 65: 1278-82. PMID 12350147 DOI: 10.1021/Np0202475  0.426
2002 Su BN, Chang LC, Park EJ, Cuendet M, Santarsiero BD, Mesecar AD, Mehta RG, Fong HH, Pezzuto JM, Kinghorn AD. Bioactive constituents of the seeds of Brucea javanica. Planta Medica. 68: 730-3. PMID 12221597 DOI: 10.1055/S-2002-33798  0.428
2002 Ito A, Chai HB, Lee D, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry. 61: 171-4. PMID 12169311 DOI: 10.1016/S0031-9422(02)00232-7  0.348
2002 Gu JQ, Park EJ, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells. Journal of Natural Products. 65: 1065-8. PMID 12141878 DOI: 10.1021/Np020042W  0.374
2002 Blatt CT, Chávez D, Chai H, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. Phytotherapy Research : Ptr. 16: 320-5. PMID 12112286 DOI: 10.1002/Ptr.889  0.457
2002 Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM. Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay. Cancer Letters. 184: 13-20. PMID 12104043 DOI: 10.1016/S0304-3835(02)00202-1  0.354
2002 Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-Sánchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, ... Pezzuto JM, et al. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. Journal of Natural Products. 65: 842-50. PMID 12088425 DOI: 10.1021/Np010322W  0.352
2002 Bhat KP, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Annals of the New York Academy of Sciences. 957: 210-29. PMID 12074974 DOI: 10.1111/J.1749-6632.2002.Tb02918.X  0.386
2002 Rimando AM, Cuendet M, Desmarchelier C, Mehta RG, Pezzuto JM, Duke SO. Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol. Journal of Agricultural and Food Chemistry. 50: 3453-7. PMID 12033810 DOI: 10.1021/Jf0116855  0.413
2002 Misico RI, Song LL, Veleiro AS, Cirigliano AM, Tettamanzi MC, Burton G, Bonetto GM, Nicotra VE, Silva GL, Gil RR, Oberti JC, Kinghorn AD, Pezzuto JM. Induction of quinone reductase by withanolides. Journal of Natural Products. 65: 677-80. PMID 12027740 DOI: 10.1021/Np0106337  0.367
2002 Gu JQ, Gills JJ, Park EJ, Mata-Greenwood E, Hawthorne ME, Axelrod F, Chavez PI, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. Journal of Natural Products. 65: 532-6. PMID 11975495 DOI: 10.1021/Np010545M  0.38
2002 Minguzzi S, Barata LE, Shin YG, Jonas PF, Chai HB, Park EJ, Pezzuto JM, Cordell GA. Cytotoxic withanolides from Acnistus arborescens. Phytochemistry. 59: 635-41. PMID 11867095 DOI: 10.1016/S0031-9422(02)00022-5  0.392
2002 Peraza-Sánchez SR, Chai HB, Shin YG, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Constituents of the leaves and twigs of Ficus hispida. Planta Medica. 68: 186-8. PMID 11859479 DOI: 10.1055/S-2002-20257  0.417
2002 Zhang H, Fan Z, Tan GT, Chai HB, Pezzuto JM, Sun H, Fong HH. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata. Journal of Natural Products. 65: 215-7. PMID 11858760 DOI: 10.1021/Np010420H  0.432
2002 Su BN, Cuendet M, Hawthorne ME, Kardono LB, Riswan S, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity. Journal of Natural Products. 65: 163-9. PMID 11858749 DOI: 10.1021/Np010451C  0.438
2002 Kandil FE, Smith MA, Rogers RB, Pépin MF, Song LL, Pezzuto JM, Seigler DS. Composition of a chemopreventive proanthocyanidin-rich fraction from cranberry fruits responsible for the inhibition of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity. Journal of Agricultural and Food Chemistry. 50: 1063-9. PMID 11853481 DOI: 10.1021/Jf011136Z  0.381
2002 Hoang VD, Tan GT, Zhang HJ, Tamez PA, Hung NV, Cuong NM, Soejarto DD, Fong HH, Pezzuto JM. Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata. Phytochemistry. 59: 325-9. PMID 11830141 DOI: 10.1016/S0031-9422(01)00454-X  0.393
2002 Kosmeder JW, Pezzuto JM. Biological effects of resveratrol. Antioxidants & Redox Signaling. 3: 1041-64. PMID 11813979 DOI: 10.1089/152308601317203567  0.346
2002 Bhat KP, Pezzuto JM. Natural modulators of estrogen biosynthesis and function as chemopreventive agents. Archives of Pharmacal Research. 24: 473-84. PMID 11794520 DOI: 10.1007/Bf02975150  0.366
2002 Burdette JE, Liu J, Lantvit D, Lim E, Booth N, Bhat KP, Hedayat S, Van Breemen RB, Constantinou AI, Pezzuto JM, Farnsworth NR, Bolton JL. Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. The Journal of Nutrition. 132: 27-30. PMID 11773503 DOI: 10.1093/Jn/132.1.27  0.303
2002 Lee D, Park EJ, Cuendet M, Axelrod F, Chavez PI, Fong HH, Pezzuto JM, Kinghorn AD. Cyclooxygenase-inhibitory and antioxidant constituents of the aerial parts of Antirhea acutata. Bioorganic & Medicinal Chemistry Letters. 11: 1565-8. PMID 11412982 DOI: 10.1016/S0960-894X(01)00129-9  0.454
2002 Cuendet M, Pezzuto JM. Non-steroidal anti-inflammatory drugs in cancer treatment Expert Opinion On Therapeutic Patents. 12: 827-835. DOI: 10.1517/13543776.12.6.827  0.362
2002 Zhang H, Qiu S, Tamez P, Tan GT, Aydogmus Z, Van Hung N, Cuong NM, Angerhofer C, Soejarto DD, Pezzuto JM, Fong HHS. Antimalarial agents from plants II. Decursivine, a new antimalarial indole alkaloid from Rhaphidophora decursiva Pharmaceutical Biology. 40: 221-224. DOI: 10.1076/Phbi.40.3.221.5832  0.436
2002 Pezzuto JM. Natural Compounds in Cancer Therapy. John Boik, Oregon Medical Press, Princeton, MN, 2001, $32.00 (ISBN 0-9648280-1-4) Pharmaceutical Biology. 40: 79-79. DOI: 10.1076/Phbi.40.1.79.5858  0.32
2002 Zhang H, Lu Z, Tan GT, Qiu S, Farnsworth NR, Pezzuto JM, Fong HHS. Polyacetyleneginsenoside-Ro, a novel triterpene saponin from Panax ginseng Tetrahedron Letters. 43: 973-977. DOI: 10.1016/S0040-4039(01)02310-3  0.377
2002 Su BN, Misico R, Jung Park E, Santarsiero BD, Mesecar AD, Fong HHS, Pezzuto JM, Douglas Kinghorn A. Isolation and characterization of bioactive principles of the leaves and stems of Physalis philadelphica Tetrahedron. 58: 3453-3466. DOI: 10.1016/S0040-4020(02)00277-6  0.42
2001 Waffo-Téguo P, Hawthorne ME, Cuendet M, Mérillon JM, Kinghorn AD, Pezzuto JM, Mehta RG. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutrition and Cancer. 40: 173-9. PMID 11962253 DOI: 10.1207/S15327914Nc402_14  0.414
2001 Silva GL, Cui B, Chávez D, You M, Chai HB, Rasoanaivo P, Lynn SM, O'Neill MJ, Lewis JA, Besterman JM, Monks A, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei Journal of Natural Products. 64: 1514-1520. PMID 11754602 DOI: 10.1021/Np010295+  0.417
2001 Mata-Greenwood E, Daeuble JF, Grieco PA, Dou J, McChesney JD, Mehta RG, Kinghorn AD, Pezzuto JM. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. Journal of Natural Products. 64: 1509-13. PMID 11754601 DOI: 10.1021/Np010212P  0.403
2001 Seo EK, Kim NC, Mi Q, Chai H, Wall ME, Wani MC, Navarro HA, Burgess JP, Graham JG, Cabieses F, Tan GT, Farnsworth NR, Pezzuto JM, Kinghorn AD. Macharistol, a new cytotoxic cinnamylphenol from the stems of Machaerium aristulatum. Journal of Natural Products. 64: 1483-5. PMID 11720542 DOI: 10.1021/Np0103158  0.365
2001 Gu JQ, Park EJ, Luyengi L, Hawthorne ME, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity Phytochemistry. 58: 121-127. PMID 11524121 DOI: 10.1016/S0031-9422(01)00180-7  0.419
2001 Tuchinda P, Pohmakotr M, Reutrakul V, Thanyachareon W, Sophasan S, Yoosook C, Santisuk T, Pezzuto JM. 2-substituted furans from Polyalthia suberosa. Planta Medica. 67: 572-5. PMID 11509987 DOI: 10.1055/S-2001-16469  0.373
2001 Lee D, Cuendet M, Vigo JS, Graham JG, Cabieses F, Fong HH, Pezzuto JM, Kinghorn AD. A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata. Organic Letters. 3: 2169-71. PMID 11440571 DOI: 10.1021/Ol015985J  0.438
2001 Ito A, Cui B, Chávez D, Chai HB, Shin YG, Kawanishi K, Kardono LBS, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic polyacetylenes from the twigs of Ochanostachys amentacea Journal of Natural Products. 64: 246-248. PMID 11430012 DOI: 10.1021/Np000484C  0.378
2001 Zhang HJ, Tamez PA, Vu DH, Ghee TT, Nguyen VH, Le TX, Le MH, Nguyen MC, Do TT, Soejarto DD, Fong HH, Pezzuto JM. Antimalarial compounds from Rhaphidophora decursiva. Journal of Natural Products. 64: 772-7. PMID 11421741 DOI: 10.1021/Np010037C  0.459
2001 Yu R, Hebbar V, Kim DW, Mandlekar S, Pezzuto JM, Kong AN. Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways. Molecular Pharmacology. 60: 217-24. PMID 11408617 DOI: 10.1124/Mol.60.1.217  0.306
2001 Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. Journal of Agricultural and Food Chemistry. 49: 2472-9. PMID 11368622 DOI: 10.1021/Jf0014157  0.347
2001 Park EJ, Lee D, Shin YG, Lantvit DD, van Breemen RB, Kinghorn AD, Pezzuto JM. Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry. Journal of Chromatography. B, Biomedical Sciences and Applications. 754: 327-32. PMID 11339276 DOI: 10.1016/S0378-4347(00)00620-4  0.35
2001 Salti GI, Kichina JV, Das Gupta TK, Uddin S, Bratescu L, Pezzuto JM, Mehta RG, Constantinou AI. Betulinic acid reduces ultraviolet-C-induced DNA breakage in congenital melanocytic naeval cells: evidence for a potential role as a chemopreventive agent. Melanoma Research. 11: 99-104. PMID 11333133 DOI: 10.1097/00008390-200104000-00003  0.303
2001 Correia SD, David JM, David JP, Chai HB, Pezzuto JM, Cordell GA. Alkyl phenols and derivatives from Tapirira obtusa. Phytochemistry. 56: 781-4. PMID 11314968 DOI: 10.1016/S0031-9422(00)00476-3  0.351
2001 Qiu SX, Nguyen VH, Le TX, Gu JQ, Lobkovsky E, Tran CK, Soejarto DD, Clardy J, Pezzuto JM, Dong Y, Mai VT, Le MH, Fong HH. A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography. Phytochemistry. 56: 775-80. PMID 11314967 DOI: 10.1016/S0031-9422(00)00463-5  0.368
2001 Waffo-Teguo P, Lee D, Cuendet M, Mérillon J, Pezzuto JM, Kinghorn AD. Two new stilbene dimer glucosides from grape (Vitis vinifera) cell cultures. Journal of Natural Products. 64: 136-8. PMID 11170689 DOI: 10.1021/Np000426R  0.436
2001 Westenburg HE, Lee KJ, Lee SK, Fong HH, van Breemen RB, Pezzuto JM, Kinghorn AD. Activity-guided isolation of antioxidative constituents of Cotinus coggygria. Journal of Natural Products. 63: 1696-8. PMID 11141121 DOI: 10.1021/Np000292H  0.526
2001 Calderón AI, Espósito-Avella M, Buitrago de Tello RE, Pezzuto JM, Sánchez C, Gupta MP. Anti-Inflammatory and Analgesic Activities of Vochysia ferruginea Pharmaceutical Biology. 39: 35-39. DOI: 10.1076/Phbi.39.1.35.5948  0.301
2001 Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HHS. Natural anti-HIV agents. Part 2: Litseaverticillol A, a prototypic litseane sesquiterpene from Litsea verticillata Tetrahedron Letters. 42: 8587-8591. DOI: 10.1016/S0040-4039(01)01852-4  0.337
2001 Chávez D, Chai HB, Chagwedera TE, Gao Q, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel stilbenes isolated from the root bark of Ekebergia benguelensis Tetrahedron Letters. 42: 3685-3688. DOI: 10.1016/S0040-4039(01)00560-3  0.427
2001 Lee D, Cuendet M, Axelrod F, Chavez PI, Fong HH, Pezzuto JM, Douglas Kinghorn A. Novel 29-nor-3,4-seco-cycloartane triterpene methyl esters from the aerial parts of Antirhea acutata Tetrahedron. 57: 7107-7112. DOI: 10.1016/S0040-4020(01)00664-0  0.366
2000 Ingolfsdottir K, Lee KLSK, Bhat KP, Lee K, Chai HB, Kristinsson H, Song LL, Gills J, Gudmundsdottir JT, Mata-Greenwood E, Jang MS, Pezzuto JM. Evaluation Of Selected Lichens From Iceland For Cancer Chemopreventive And Cytotoxic Activity Pharmaceutical Biology. 38: 313-317. PMID 21214483 DOI: 10.1076/1388-0209(200009)3841-Aft313  0.429
2000 Kouzi SA, Chatterjee P, Pezzuto JM, Hamann MT. Microbial transformations of the antimelanoma agent betulinic acid. Journal of Natural Products. 63: 1653-7. PMID 11141108 DOI: 10.1021/Np000343A  0.317
2000 Cho KH, Pezzuto JM, Bolton JL, Steele VE, Kelloff GJ, Lee SK, Constantinou A. Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity. European Journal of Cancer (Oxford, England : 1990). 36: 2146-56. PMID 11044654 DOI: 10.1016/S0959-8049(00)00300-2  0.445
2000 Chang LC, Song LL, Park EJ, Luyengi L, Lee KJ, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive constituents of Thuja occidentalis Journal of Natural Products. 63: 1235-1238. PMID 11000026 DOI: 10.1021/Np0001575  0.471
2000 Qiu SX, Li XC, Xiong Y, Dong Y, Chai H, Farnsworth NR, Pezzuto JM, Fong HHS. Isolation and characterization of cytotoxic saponin chloromaloside a from Chlorophytum malayense Planta Medica. 66: 587-590. PMID 10985095 DOI: 10.1055/S-2000-8600  0.37
2000 Chatterjee P, Kouzi SA, Pezzuto JM, Hamann MT. Biotransformation of the antimelanoma agent betulinic acid by Bacillus megaterium ATCC 13368. Applied and Environmental Microbiology. 66: 3850-5. PMID 10966400 DOI: 10.1128/Aem.66.9.3850-3855.2000  0.347
2000 Nikolic D, Habibi-Goudarzi S, Corley DG, Gafner S, Pezzuto JM, van Breemen RB. Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry. Analytical Chemistry. 72: 3853-9. PMID 10959973 DOI: 10.1021/Ac0000980  0.347
2000 Jeong HJ, Chang LC, Kim HK, Kim IH, Kinghorn AD, Pezzuto JM. Aromatase inhibitors from Isodon excisus var. coreanus. Archives of Pharmacal Research. 23: 243-5. PMID 10896056 DOI: 10.1007/Bf02976453  0.419
2000 Chang LC, Chávez D, Song LL, Farnsworth NR, Pezzuto JM, Kinghorn AD. Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea Organic Letters. 2: 515-518. PMID 10814365 DOI: 10.1021/Ol990407C  0.363
2000 Peraza-Sánchez SR, Chávez D, Chai HB, Shin YG, García R, Mejía M, Fairchild CR, Lane KE, Menendez AT, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the roots of Ekmanianthe longiflora. Journal of Natural Products. 63: 492-5. PMID 10785421 DOI: 10.1021/Np990528L  0.375
2000 Seo EK, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 5-(4-Hydroxyphenethenyl)-4,7-dimethoxycoumarin, a new constituent of Monotes engleri Planta Medica. 66: 182-184. PMID 10763599 DOI: 10.1055/S-0029-1243128  0.391
2000 Adeniyi BA, Fong HH, Pezzuto JM, Luyengi L, Odelola HA. Antibacterial activity of diospyrin, isodiospyrin and bisisodiospyrin from the root of Diospyros piscatoria (Gurke) (Ebenaceae). Phytotherapy Research : Ptr. 14: 112-7. PMID 10685108 DOI: 10.1002/(Sici)1099-1573(200003)14:2<112::Aid-Ptr488>3.0.Co;2-T  0.331
2000 Lee SK, Pezzuto JM. Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity. Archives of Pharmacal Research. 22: 559-64. PMID 10615860 DOI: 10.1007/Bf02975326  0.565
2000 Chang LC, Chávez D, Gills JJ, Fong HH, Pezzuto JM, Kinghorn A. Rubiasins A–C, new anthracene derivatives from the roots and stems of Rubia cordifolia Tetrahedron Letters. 41: 7157-7162. DOI: 10.1016/S0040-4039(00)01205-3  0.44
2000 Ito A, Chai H, Shin YG, Garcı́a R, Mejı́a M, Gao Q, Fairchild CR, Lane KE, Menendez AT, Farnsworth NR, Cordell GA, Pezzuto JM, Douglas Kinghorn A. Cytotoxic Constituents of the Roots of Exostema acuminatum Tetrahedron. 56: 6401-6405. DOI: 10.1016/S0040-4020(00)00584-6  0.434
2000 Chang LC, Bhat KP, Fong HH, Pezzuto JM, Kinghorn A. Novel Bioactive Steroidal Alkaloids from Pachysandra procumbens Tetrahedron. 56: 3133-3138. DOI: 10.1016/S0040-4020(00)00232-5  0.319
2000 Kandil FE, Song L, Pezzuto JM, Marley K, Seigler DS, Smith MAL. Isolation of oligomeric proanthocyanidins from flavonoid-producing cell cultures In Vitro Cellular & Developmental Biology - Plant. 36: 492-500. DOI: 10.1007/S11627-000-0088-1  0.436
2000 Calderon AI, Angerhofer CK, Pezzuto JM, Farnsworth NR, Foster RB, Condit RS, Gupta MP, Soejarto DD. Forest plot as a tool to demonstrate the pharmaceutical potential of plants in a tropical forest of Panama Economic Botany. 54: 278-294. DOI: 10.1007/Bf02864782  0.316
1999 Cui B, Lee YH, Chai H, Tucker JC, Fairchild CR, Raventos-Suarez C, Long B, Lane KE, Menendez AT, Beecher CW, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic sesquiterpenoids from Ratibida columnifera. Journal of Natural Products. 62: 1545-50. PMID 10579870 DOI: 10.1021/Np990260Y  0.393
1999 Chung HS, Chang LC, Lee SK, Shamon LA, Van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity Journal of Agricultural and Food Chemistry. 47: 36-41. PMID 10563845 DOI: 10.1021/Jf980784O  0.55
1999 Ito A, Lee YH, Chai HB, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. 1',2',3',4'-Tetradehydrotubulosine, a cytotoxic alkaloid from Pogonopus speciosus Journal of Natural Products. 62: 1346-1348. PMID 10514334 DOI: 10.1021/np990255u  0.357
1999 Cui B, Chai H, Dong Y, Horgen FD, Hansen B, Madulid DA, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Quinoline alkaloids from Acronychia laurifolia Phytochemistry. 52: 95-98. PMID 10466225 DOI: 10.1016/S0031-9422(99)00039-4  0.462
1999 Jeong HJ, Shin YG, Kim IH, Pezzuto JM. Inhibition of aromatase activity by flavonoids. Archives of Pharmacal Research. 22: 309-12. PMID 10403137 DOI: 10.1007/Bf02976369  0.382
1999 Chatterjee P, Pezzuto JM, Kouzi SA. Glucosidation of betulinic acid by Cunninghamella species. Journal of Natural Products. 62: 761-3. PMID 10346964 DOI: 10.1021/Np980432B  0.361
1999 Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM. Diterpenes from the berries of Juniperus excelsa. Phytochemistry. 50: 1195-9. PMID 10234860 DOI: 10.1016/S0031-9422(98)00675-X  0.436
1999 Lee SK, Luyengi L, Gerhäuser C, Mar W, Lee K, Mehta RG, Kinghorn AD, Pezzuto JM. Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity. Cancer Letters. 136: 59-65. PMID 10211940 DOI: 10.1016/S0304-3835(98)00309-7  0.497
1999 Lin LZ, Hu SF, Chu M, Chan TM, Chai H, Angerhofer CK, Pezzuto JM, Cordell GA. Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi. Phytochemistry. 50: 829-34. PMID 10192967 DOI: 10.1016/S0031-9422(98)00580-9  0.417
1999 Angerhofer CK, Guinaudeau H, Wongpanich V, Pezzuto JM, Cordell GA. Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids. Journal of Natural Products. 62: 59-66. PMID 9917283 DOI: 10.1021/Np980144F  0.445
1999 Kim DS, Pezzuto JM, Pisha E. Synthesis of betulinic acid derivatives with activity against human melanoma. Bioorganic & Medicinal Chemistry Letters. 8: 1707-12. PMID 9873420 DOI: 10.1016/S0960-894X(98)00295-9  0.336
1999 David JP, de O. Santos AJ, da S. Guedes ML, David JM, Chai H, Pezzuto JM, Angerhofer CK, Cordell GA. Sesquiterpene Lactones from Ambrosia artemisiaefolia (Asteraceae) Pharmaceutical Biology. 37: 165-168. DOI: 10.1076/Phbi.37.2.165.6077  0.397
1999 Ulubelen A, Topçu G, Chai H, Pezzuto JM. Cytotoxic Activity of Diterpenoids Isolated from Salvia hypargeia Pharmaceutical Biology. 37: 148-151. DOI: 10.1076/Phbi.37.2.148.6082  0.402
1999 Yang S, Cordell GA, Chai H, Jang M, Pezzuto JM. Cytotoxic Activity of Some Indole Derivatives and Indole Metabolites of Streptomyces staurosporeus Pharmaceutical Biology. 37: 67-70. DOI: 10.1076/Phbi.37.1.67.6315  0.375
1999 Qiu SX, Lu ZZ, Luyengi L, Lee SK, Pezzuto JM, Farnsworth NR, Thompson LU, Fong HHS. Isolation and characterization of flaxseed (Linum usitatissimum) constituents Pharmaceutical Biology. 37: 1-7. DOI: 10.1076/Phbi.37.1.1.6320  0.453
1999 Shin YG, Cordell GA, Dong Y, Pezzuto JM, Appa Rao AVN, Ramesh M, Kumar BR, Radhakishan M. Rapid identification of cytotoxic alkenyl catechols in Semecarpus anacardium using bioassay-linked high performance liquid chromatography-electrospray/mass spectrometric analysis Phytochemical Analysis. 10: 208-212. DOI: 10.1002/(Sici)1099-1565(199907/08)10:4<208::Aid-Pca457>3.0.Co;2-9  0.43
1998 El Sayed KA, Hamann MT, Waddling CA, Jensen C, Lee SK, Dunstan CA, Pezzuto JM. Structurally Novel Bioconversion Products of the Marine Natural Product Sarcophine Effectively Inhibit JB6 Cell Transformation. The Journal of Organic Chemistry. 63: 7449-7455. PMID 11672397 DOI: 10.1021/Jo9813134  0.432
1998 Qiu SX, Sun HD, Lobkovsky E, Chai H, Clardy J, Farnsworth NR, Pezzuto JM, Fong HHS. Megathyrin B: A cytotoxic diterpene from isodon megathyrsus Planta Medica. 64: 728-731. PMID 10075544 DOI: 10.1055/S-2006-957567  0.334
1998 Cui B, Chai H, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Novel cytotoxic acylated oligorhamnosides from Mezzettia leptopoda Journal of Natural Products. 61: 1535-1538. PMID 9868159 DOI: 10.1021/Np980270J  0.335
1998 Lee SK, Cui B, Mehta RR, Kinghorn AD, Pezzuto JM. Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica. Chemico-Biological Interactions. 115: 215-28. PMID 9851291 DOI: 10.1016/S0009-2797(98)00073-8  0.438
1998 Chang LC, Bhat KPL, Pisha E, Kennelly EJ, Fong HHS, Pezzuto JM, Kinghorn AD. Activity-guided isolation of steroidal alkaloid antiestrogen-binding site inhibitors from Pachysandra procumbens Journal of Natural Products. 61: 1257-1262. PMID 9784163 DOI: 10.1021/Np980162X  0.363
1998 Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H, Jang M, Pezzuto JM, Dannenberg AJ. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. The Journal of Biological Chemistry. 273: 21875-82. PMID 9705326 DOI: 10.1074/Jbc.273.34.21875  0.361
1998 Dharmaratne HR, Wanigasekera WM, Mata-Greenwood E, Pezzuto JM. Inhibition of human immunodeficiency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum. Planta Medica. 64: 460-1. PMID 9690350 DOI: 10.1055/S-2006-957483  0.338
1998 Lee SK, Qing WG, Mar W, Luyengi L, Mehta RG, Kawanishi K, Fong HH, Beecher CW, Kinghorn AD, Pezzuto JM. Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase C. The Journal of Biological Chemistry. 273: 19829-33. PMID 9677417 DOI: 10.1074/Jbc.273.31.19829  0.489
1998 Poobrasert O, Constant HL, Beecher CWW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA, Santisuk T, Reutrakul V. Xanthones from the twigs of Mammea siamensis Phytochemistry. 47: 1661-1663. PMID 9612959 DOI: 10.1016/S0031-9422(97)00820-0  0.431
1998 Cui B, Chai H, Constant HL, Santisuk T, Reutrakul V, Beecher CWW, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Limonoids from Azadirachta excelsa Phytochemistry. 47: 1283-1287. PMID 9611828 DOI: 10.1016/S0031-9422(97)00711-5  0.466
1998 Gamez EJ, Luyengi L, Lee SK, Zhu LF, Zhou BN, Fong HH, Pezzuto JM, Kinghorn AD. Antioxidant flavonoid glycosides from Daphniphyllum calycinum. Journal of Natural Products. 61: 706-8. PMID 9599286 DOI: 10.1021/Np9800203  0.528
1998 Schmidt ML, Kuzmanoff KL, Ling-Indeck L, Pezzuto JM. Betulinic acid induces apoptosis in human neuroblastoma cell lines. European Journal of Cancer (Oxford, England : 1990). 33: 2007-10. PMID 9516843 DOI: 10.1016/S0959-8049(97)00294-3  0.309
1998 David JM, Chávez JP, Chai HB, Pezzuto JM, Cordell GA. Two new cytotoxic compounds from Tapirira guianensis. Journal of Natural Products. 61: 287-9. PMID 9514013 DOI: 10.1021/Np970422V  0.406
1998 Arda N, Gören N, Kuru A, Pengsuparp T, Pezzuto JM, Qiu SX, Cordell GA. Saniculoside N from Sanicula europaea L. Journal of Natural Products. 60: 1170-3. PMID 9392884 DOI: 10.1021/Np9701790  0.314
1998 Jang M, Pezzuto JM. Resveratrol blocks eicosanoid production and chemically-induced cellular transformation: Implications for cancer chemoprevention Pharmaceutical Biology. 36: 28-34. DOI: 10.1076/Phbi.36.6.28.4553  0.406
1998 Ito A, Shamon LA, Yu B, Mata-Greenwood E, Lee SK, Van Breemen RB, Mehta RG, Farnsworth NR, Fong HHS, Pezzuto JM, Kinghorn AD. Antimutagenic Constituents of Casimiroa edulis with Potential Cancer Chemopreventive Activity Journal of Agricultural and Food Chemistry. 46: 3509-3516. DOI: 10.1021/Jf9802373  0.534
1998 Mebe PP, Cordell GA, Pezzuto JM. Pentacyclic triterpenes and naphthoquinones from Euclea divinorum Phytochemistry. 47: 311-313. DOI: 10.1016/S0031-9422(97)00398-1  0.417
1997 Lin YM, Anderson H, Flavin MT, Pai YH, Mata-Greenwood E, Pengsuparp T, Pezzuto JM, Schinazi RF, Hughes SH, Chen FC. In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora. Journal of Natural Products. 60: 884-8. PMID 9322359 DOI: 10.1021/Np9700275  0.345
1997 Chang LC, Gerhäuser C, Song L, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase. Journal of Natural Products. 60: 869-73. PMID 9322358 DOI: 10.1021/Np970236P  0.462
1997 Seo EK, Silva GL, Chai HB, Chagwedera TE, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic prenylated flavanones from Monotes engleri. Phytochemistry. 45: 509-15. PMID 9190085 DOI: 10.1016/S0031-9422(96)00871-0  0.44
1997 Lu GH, Wang FP, Pezzuto JM, Tam TC, Williams ID, Che CT. 10-Epi-olguine from Rabdosia ternifolia. Journal of Natural Products. 60: 425-7. PMID 9182128 DOI: 10.1021/Np960689E  0.415
1997 Horgen FD, Guinaudeau H, Pezzuto JM, Soejarto DD, Farnsworth NR, Agcaoili F, de los Reyes G, Edrada RA. Isolation and structure elucidation of ardisenone: a new, cytotoxic alkenylphenol from Ardisia iwahigensis. Journal of Natural Products. 60: 533-5. PMID 9170297 DOI: 10.1021/Np970049R  0.461
1997 Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, Van Breemen RB, Bolton JL. Bioreductive activation of catechol estrogen-ortho-quinones: Aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity Carcinogenesis. 18: 1093-1101. PMID 9163701 DOI: 10.1093/Carcin/18.5.1093  0.303
1997 Caliş I, Yürüker A, Taşdemir D, Wright AD, Sticher O, Luo YD, Pezzuto JM. Cycloartane triterpene glycosides from the roots of Astragalus melanophrurius. Planta Medica. 63: 183-6. PMID 9140236 DOI: 10.1055/S-2006-957642  0.373
1997 MacKinnon S, Durst T, Arnason JT, Angerhofer C, Pezzuto J, Sanchez-Vindas PE, Poveda LJ, Gbeassor M. Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives. Journal of Natural Products. 60: 336-41. PMID 9134742 DOI: 10.1021/Np9605394  0.364
1997 Pezzuto JM. Plant-derived anticancer agents. Biochemical Pharmacology. 53: 121-33. PMID 9037244 DOI: 10.1016/S0006-2952(96)00654-5  0.317
1997 Shamon LA, Pezzuto JM, Graves JM, Mehta RR, Wangcharoentrakul S, Sangsuwan R, Chaichana S, Tuchinda P, Cleason P, Reutrakul V. Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii. Cancer Letters. 112: 113-7. PMID 9029176 DOI: 10.1016/S0304-3835(96)04554-5  0.381
1997 Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (New York, N.Y.). 275: 218-20. PMID 8985016 DOI: 10.1126/Science.275.5297.218  0.395
1997 Mbwambo ZH, Lee SK, Mshiu EN, Pezzuto JM, Kinghorn AD. Constituents from the stem wood of Euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity. Journal of Natural Products. 59: 1051-5. PMID 8946746 DOI: 10.1021/Np960412E  0.506
1997 Huang L, Fullas F, McGivney RJ, Brown DM, Wani MC, Wall ME, Tucker JC, Beecher CW, Pezzuto JM, Kinghorn AD. A new prenylated flavonol from the root of Petalostemon purpureus. Journal of Natural Products. 59: 290-2. PMID 8882432 DOI: 10.1021/np960068l  0.345
1997 Kennelly EJ, Gerhäuser C, Song LL, Graham JG, Beecher CWW, Pezzuto JM, Kinghorn AD. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos) Journal of Agricultural and Food Chemistry. 45: 3771-3777. DOI: 10.1021/Jf970246W  0.485
1997 Cui B, Chai H, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Douglas Kinghorn A. Novel cytotoxic 1H-cyclopenta[b]benzofuran lignans from Aglaia elliptica Tetrahedron. 53: 17625-17632. DOI: 10.1016/S0040-4020(97)10231-9  0.46
1997 Long L, Lee SK, Chai H, Rasoanaivo P, Gao Q, Navarro H, Wall ME, Wani MC, Farnsworth NR, Cordell GA, Pezzuto JM, Douglas Kinghorn A. Novel bioactive phenanthrene derivatives from Domohinea perrieri Tetrahedron. 53: 15663-15670. DOI: 10.1016/S0040-4020(97)10058-8  0.499
1997 Öksüz S, Gürek F, Yang S, Lin L, Cordell GA, Pezzuto JM, Wagner H, Lotter H. Paralinones A and B, novel diterpene esters from Euphorbia paralias Tetrahedron. 53: 3215-3222. DOI: 10.1016/S0040-4020(97)00032-X  0.377
1997 Silva GL, Gil RR, Cui B, Chai H, Santisuk T, Srisook E, Reutrakul V, Tuchinda P, Sophasan S, Sujarit S, Upatham S, Lynn SM, Farthing JE, Yang S, Lewis JA, ... ... Pezzuto JM, et al. Novel cytotoxic ring-a seco-cycloartane triterpenes from Gardenia coronaria and G. sootepensis Tetrahedron. 53: 529-538. DOI: 10.1016/S0040-4020(96)01003-4  0.433
1997 Chung MS, Kim NC, Long L, Shamon L, Ahmad WY, Sagrero-Nieves L, Kardono LBS, Kennelly EJ, Pezzuto JM, Soejarto DD, Kinghorn AD. Dereplication of saccharide and polyol constituents of candidate sweet-tasting plants: Isolation of the sesquiterpene glycoside mukurozioside IIb as a sweet principle of Sapindus rarak Phytochemical Analysis. 8: 49-54. DOI: 10.1002/(Sici)1099-1565(199703)8:2<49::Aid-Pca339>3.0.Co;2-C  0.389
1996 Wall ME, Wani MC, Brown DM, Fullas F, Olwald JB, Josephson FF, Thornton NM, Pezzuto JM, Beecher CW, Farnsworth NR, Cordell GA, Kinghorn AD. Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 3: 281-5. PMID 23195084 DOI: 10.1016/S0944-7113(96)80067-5  0.347
1996 Pengsuparp T, Serit M, Hughes SH, Soejarto DD, Pezzuto JM. Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of Calophyllum teysmannii Journal of Natural Products. 59: 839-842. PMID 8864237 DOI: 10.1021/Np960399Y  0.314
1996 Luyengi L, Suh N, Fong HH, Pezzuto JM, Kinghorn AD. A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 43: 409-12. PMID 8862033 DOI: 10.1016/0031-9422(96)00258-0  0.421
1996 Sun HD, Qiu SX, Lin LZ, Wang ZY, Lin ZW, Pengsuparp T, Pezzuto JM, Fong HH, Cordell GA, Farnsworth NR. Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase. Journal of Natural Products. 59: 525-7. PMID 8778243 DOI: 10.1021/Np960149H  0.345
1996 Pengsuparp T, Kingston DG, Neidigh KA, Cordell GA, Pezzuto JM. Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol. Chemico-Biological Interactions. 101: 103-14. PMID 8760392 DOI: 10.1016/0009-2797(96)03713-1  0.344
1996 Sturm S, Gil RR, Chai HB, Ngassapa OD, Santisuk T, Reutrakul V, Howe A, Moss M, Besterman JM, Yang SL, Farthing JE, Tait RM, Lewis JA, O'Neill MJ, Farnsworth NR, ... ... Pezzuto JM, et al. Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity. Journal of Natural Products. 59: 658-63. PMID 8759161 DOI: 10.1021/Np960370U  0.47
1996 Oksüz S, Gürek F, Lin LZ, Gil RR, Pezzuto JM, Cordell GA. Aleppicatines A and B from Euphorbia aleppica. Phytochemistry. 42: 473-8. PMID 8688177 DOI: 10.1016/0031-9422(95)00889-6  0.369
1996 Lee IS, Shamon LA, Chai HB, Chagwedera TE, Besterman JM, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cell-cycle specific cytotoxicity mediated by rearranged ent-kaurene diterpenoids isolated from Parinari curatellifolia. Chemico-Biological Interactions. 99: 193-204. PMID 8620568 DOI: 10.1016/0009-2797(95)03669-5  0.464
1996 Tan GT, Lee S, Lee IS, Chen J, Leitner P, Besterman JM, Kinghorn AD, Pezzuto JM. Natural-product inhibitors of human DNA ligase I. The Biochemical Journal. 314: 993-1000. PMID 8615799 DOI: 10.1042/Bj3140993  0.488
1996 Lin LZ, Hu SF, Chai HB, Pengsuparp T, Pezzuto JM, Cordell GA, Ruangrungsi N. Lycorine alkaloids from Hymenocallis littoralis. Phytochemistry. 40: 1295-8. PMID 7492374 DOI: 10.1016/0031-9422(95)00372-E  0.388
1996 Poobrasert O, Chai H, Pezzuto JM, Cordell GA. Cytotoxic Degradation Product of Physostigmine Journal of Natural Products. 59: 1087-1089. DOI: 10.1021/Np960518+  0.436
1996 Cordell GA, Beecher CWW, Kinghorn AD, Pezzuto JM, Constant HL, Chai H, Fang L, Seo E, Long L, Cui B, Slowing-Barillas K. The dereplication of plant-derived natural products Studies in Natural Products Chemistry. 19: 749-791. DOI: 10.1016/S1572-5995(96)80018-4  0.368
1996 Yoshida T, Hashimoto T, Takaoka S, Kan Y, Tori M, Asakawa Y, Pezzuto JM, Pengsuparp T, Cordell GA. Phenolic constituents of the liverwort: Four novel cyclic bisbibenzyl dimers from Blasia pusilla L Tetrahedron. 52: 14487-14500. DOI: 10.1016/0040-4020(96)00889-7  0.367
1995 Swanson SM, Pezzuto JM. Enhancement Of Benzo(A)Pyrene Metabolism Mediated By Retinol Acetate In Cultured Human Bronchial Epithelial-Cells Oncology Reports. 2: 1011-1015. PMID 21597844 DOI: 10.3892/Or.2.6.1011  0.321
1995 Fullas F, Brown DM, Wani MC, Wall ME, Chagwedera TE, Farnsworth NR, Pezzuto JM, Kinghorn AD. Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera. Journal of Natural Products. 58: 1625-8. PMID 8676132 DOI: 10.1021/Np50124A027  0.458
1995 Mehta RG, Liu J, Constantinou A, Thomas CF, Hawthorne M, You M, Gerhüser C, Pezzuto JM, Moon RC, Moriarty RM. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 16: 399-404. PMID 7859373 DOI: 10.1093/Carcin/16.2.399  0.435
1995 Oksüz S, Gil RR, Chai H, Pezzuto JM, Cordell GA, Ulubelen A. Biologically active compounds from the Euphorbiaceae; 2. Two triterpenoids of Euphorbia cyparissias. Planta Medica. 60: 594-6. PMID 7809217 DOI: 10.1055/S-2006-959586  0.418
1995 Wickramaratne DBM, Mar W, Chai H, Castillo JJ, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Bursera permollis Planta Medica. 61: 80-81. PMID 7701001 DOI: 10.1055/S-2006-958008  0.362
1995 Gil RR, Lin LZ, Chai HB, Pezzuto JM, Cordell GA. Cardenolides from Nierembergia aristata. Journal of Natural Products. 58: 848-56. PMID 7673928 DOI: 10.1021/Np50120A005  0.375
1995 You M, Wickramaratne DB, Silva GL, Chai H, Chagwedera TE, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. (-)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells. Journal of Natural Products. 58: 598-604. PMID 7623038 DOI: 10.1021/Np50118A021  0.377
1995 Gerhäuser C, Mar W, Lee SK, Suh N, Luo Y, Kosmeder J, Luyengi L, Fong HHS, KingHorn AD, Moriarty RM, Mehta RG, Constantinou A, Moon RC, Pezzuto JM. Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase. Nature Medicine. 1: 260-266. PMID 7585044 DOI: 10.1038/Nm0395-260  0.427
1995 Pengsuparp T, Cai L, Constant H, Fong HH, Lin LZ, Kinghorn AD, Pezzuto JM, Cordell GA, Ingolfsdóttir K, Wagner H. Mechanistic evaluation of new plant-derived compounds that inhibit HIV-1 reverse transcriptase. Journal of Natural Products. 58: 1024-31. PMID 7561895 DOI: 10.1021/Np50121A006  0.377
1995 Silva GL, Chai H, Gupta MP, Farnsworth NR, Cordell GA, Pezzuto JM, Beecher CW, Kinghorn AD. Cytotoxic biflavonoids from Selaginella willdenowii. Phytochemistry. 40: 129-34. PMID 7546547 DOI: 10.1016/0031-9422(95)00212-P  0.391
1995 Oksüz S, Gürek F, Gil RR, Pengsuparp T, Pezzuto JM, Cordell GA. Four diterpene esters from Euphorbia myrsinites. Phytochemistry. 38: 1457-62. PMID 7540394 DOI: 10.1016/0031-9422(94)00806-5  0.35
1995 Sun HD, Lin ZW, Niu FD, Lin LZ, Chai HB, Pezzuto JM, Cordell GA. Cytotoxic ent-kaurene diterpenoids from three Isodon species. Phytochemistry. 38: 437-42. PMID 7539618 DOI: 10.1016/0031-9422(94)00626-5  0.4
1995 Lin LZ, Hu SF, Zaw K, Angerhofer CK, Chai H, Pezzuto JM, Cordell GA, Lin J, Zheng DM. Thalifaberidine, a cytotoxic aporphine-benzylisoquinoline alkaloid from Thalictrum faberi. Journal of Natural Products. 57: 1430-6. PMID 7528786 DOI: 10.1021/Np50112A013  0.421
1995 Sun HD, Lin ZW, Niu FD, Lin LZ, Chai H, Pezzuto JM, Cordell GA. Cytotoxic diterpenoids from Isodon megathyrsus. Journal of Natural Products. 57: 1424-9. PMID 7528785 DOI: 10.1021/Np50112A012  0.437
1995 Falch BS, König GM, Wright AD, Sticher O, Angerhofer CK, Pezzuto JM, Bachmann H. Biological activities of cyanobacteria: evaluation of extracts and pure compounds. Planta Medica. 61: 321-8. PMID 7480178 DOI: 10.1055/S-2006-958092  0.436
1995 Kennelly EJ, Cai L, Long L, Shamon L, Zaw K, Zhou BN, Pezzuto JM, Kinghorn AD. Novel highly sweet secodammarane glycosides from Pterocarya paliurus Journal of Agricultural and Food Chemistry. 43: 2602-2607. DOI: 10.1021/Jf00058A009  0.396
1995 Lee I, Ma X, Chai H, Madulid DA, Lamont RB, O'Neill MJ, Besterman JM, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, Kinghorn AD. Novel cytotoxic labdane diterpenoids from Neouvaria acuminatissima Tetrahedron. 51: 21-28. DOI: 10.1016/0040-4020(94)00945-Q  0.369
1994 Luyengi L, Pezzuto JM, Waller DP, Beecher CW, Fong HH, Che CT, Bowen PE. Linusitamarin, a new phenylpropanoid glucoside from Linum usitatissimum. Journal of Natural Products. 56: 2012-5. PMID 8289068 DOI: 10.1021/Np50101A026  0.415
1994 Novelo M, Cruz JG, Hernández L, Pereda-Miranda R, Chai H, Mar W, Pezzuto JM. Cytotoxic constituents from Hyptis verticillata. Journal of Natural Products. 56: 1728-36. PMID 8277312 DOI: 10.1021/Np50100A011  0.473
1994 Oksüz S, Shieh HL, Pezzuto JM, Ozhatay N, Cordell GA. Biologically active compounds from the Euphorbiaceae; Part 1. Triterpenoids of Euphorbia nicaeensis subsp. glareosa. Planta Medica. 59: 472-3. PMID 8255939 DOI: 10.1055/S-2006-959736  0.419
1994 Likhitwitayawuid K, Angerhofer CK, Chai H, Pezzuto JM, Cordell GA, Ruangrungsi N. Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei. Journal of Natural Products. 56: 1468-78. PMID 8254346 DOI: 10.1021/Np50099A005  0.438
1994 Ngassapa O, Soejarto DD, Pezzuto JM, Farnsworth NR. Quinone-methide triterpenes and salaspermic acid from Kokoona ochracea Journal of Natural Products. 57: 1-8. PMID 8158155 DOI: 10.1021/Np50103A001  0.382
1994 Fullas F, Hussain RA, Chai HB, Pezzuto JM, Soejarto DD, Douglas Kinghorn A. Cytotoxic constituents of Baccharis gaudichaudiana Journal of Natural Products. 57: 801-807. PMID 7931367 DOI: 10.1021/Np50108A017  0.462
1994 You M, Ma X, Mukherjee R, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Indole alkaloids from Peschiera laeta that enhance vinblastine-mediated cytotoxicity with multidrug-resistant cells. Journal of Natural Products. 57: 1517-22. PMID 7853002 DOI: 10.1021/Np50113A007  0.381
1994 König GM, Wright AD, Sticher O, Angerhofer CK, Pezzuto JM. Biological activities of selected marine natural products. Planta Medica. 60: 532-7. PMID 7809206 DOI: 10.1055/S-2006-959565  0.318
1994 Chen IS, Wu SJ, Tsai IL, Wu TS, Pezzuto JM, Lu MC, Chai H, Suh N, Teng CM. Chemical and bioactive constituents from Zanthoxylum simulans Journal of Natural Products. 57: 1206-1211. PMID 7798955 DOI: 10.1021/Np50111A003  0.471
1994 Ma X, Lee IS, Chai HB, Zaw K, Farnsworth NR, Soejarto DD, Cordell GA, Pezzuto JM, D. Kinghorn A. Cytotoxic clerodane diterpenes from Polyalthia barnesii Phytochemistry. 37: 1659-1662. PMID 7766002 DOI: 10.1016/S0031-9422(00)89587-4  0.335
1994 Rimando AM, Pezzuto JM, Farnsworth NR, Santisuk T, Reutrakul V, Kawanishi K. New lignans from Anogeissus acuminata with HIV-1 reverse transcriptase inhibitory activity. Journal of Natural Products. 57: 896-904. PMID 7525878 DOI: 10.1021/Np50109A004  0.456
1994 Pengsuparp T, Cai L, Fong HH, Kinghorn AD, Pezzuto JM, Wani MC, Wall ME. Pentacyclic triterpenes derived from Maprounea africana are potent inhibitors of HIV-1 reverse transcriptase. Journal of Natural Products. 57: 415-8. PMID 7515410 DOI: 10.1021/Np50105A017  0.317
1994 Cordell GA, Angerhofer CK, Pezzuto JM. Recent studies on cytotoxic, anti-HIV and antimalarial agents from plants Pure and Applied Chemistry. 66: 2283-2286. DOI: 10.1351/Pac199466102283  0.481
1994 Rimando AM, Pezzuto JM, Farnsworth NR, Santisuk T, Reutrakul V. Revision of the NMR Assignments of Pterostilbene and of Dihydrodehydrodiconieferyl alcohol: Cytotoxic Constituents fromAnogeissus acuminata Natural Product Letters. 4: 267-272. DOI: 10.1080/10575639408043917  0.366
1994 Gören N, Tahtasakal E, Pezzuto JM, Cordell GA, Shwarzt B, Prokscht P. Sesquiterpene lactones from Tanacetum argenteum Phytochemistry. 36: 389-392. DOI: 10.1016/S0031-9422(00)97081-X  0.367
1994 Luyengi L, Lee I, Mar W, Fong HH, Pezzuto JM, Kinghorn A. Rotenoids and chalcones from Mundulea sericea that inhibit phorbol ester-induced ornithine decarboxylase activity Phytochemistry. 36: 1523-1526. DOI: 10.1016/S0031-9422(00)89755-1  0.379
1993 Pereda-Miranda R, Hernández L, Villavicencio MJ, Novelo M, Ibarra P, Chai H, Pezzuto JM. Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata. Journal of Natural Products. 56: 583-93. PMID 8496706 DOI: 10.1021/Np50094A019  0.415
1993 Pereda-Miranda R, Mata R, Anaya AL, Wickramaratne DB, Pezzuto JM, Kinghorn AD. Tricolorin A, major phytogrowth inhibitor from Ipomoea tricolor. Journal of Natural Products. 56: 571-82. PMID 8496705 DOI: 10.1021/Np50094A018  0.428
1993 Saifah E, Puripattanavong J, Likhitwitayawuid K, Cordell GA, Chai H, Pezzuto JM. Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells. Journal of Natural Products. 56: 473-7. PMID 8496701 DOI: 10.1021/Np50094A004  0.409
1993 Likhitwitayawuid K, Angerhofer CK, Cordell GA, Pezzuto JM, Ruangrungsi N. Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta. Journal of Natural Products. 56: 30-8. PMID 8450319 DOI: 10.1021/Np50091A005  0.37
1993 Lin LZ, Shieh HL, Angerhofer CK, Pezzuto JM, Cordell GA, Xue L, Johnson ME, Ruangrungsi N. Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata. Journal of Natural Products. 56: 22-9. PMID 8450318 DOI: 10.1021/Np50091A004  0.39
1993 Somanabandhu A, Nitayangkura S, Mahidol C, Ruchirawat S, Likhitwitayawuid K, Shieh HL, Chai H, Pezzuto JM, Cordell GA. 1H- and 13C-nmr assignments of phyllanthin and hypophyllanthin: lignans that enhance cytotoxic responses with cultured multidrug-resistant cells. Journal of Natural Products. 56: 233-9. PMID 8385184 DOI: 10.1021/Np50092A008  0.339
1993 Ngassapa O, Beecher CW, Pezzuto JM, Farnsworth NR, Henderson TO, Boye GL. Isolation of echinocystic acid-3-O-sulfate, a new triterpene, from Tetrapleura tetraptera, and evaluation of the mutagenic potential of molluscicidal extracts and isolates. Journal of Natural Products. 56: 1872-7. PMID 8289059 DOI: 10.1021/Np50101A002  0.397
1993 Ngassapa O, Soejarto DD, Pezzuto JM, Farnsworth NR, Che CT. Further lupane lactones from Kokoona ochracea Journal of Natural Products. 56: 1676-1681. PMID 8277307 DOI: 10.1021/Np50100A003  0.425
1993 Baek NI, Chung MS, Shamon L, Kardono LBS, Tsauri S, Padmawinata K, Pezzuto JM, Soejarto DD, Kinghorn AD. Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei Journal of Natural Products. 56: 1532-1538. PMID 8254348 DOI: 10.1021/Np50099A011  0.33
1993 Antoun MD, Mendoza NT, Ríos YR, Proctor GR, Wickramaratne DB, Pezzuto JM, Kinghorn AD. Cytotoxicity of Hymenocallis expansa alkaloids. Journal of Natural Products. 56: 1423-5. PMID 8229020 DOI: 10.1021/Np50098A030  0.347
1993 Likhitwitayawuid K, Angerhofer CK, Chai H, Pezzuto JM, Cordell GA, Ruangrungsi N. Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile. Journal of Natural Products. 56: 1331-8. PMID 8229016 DOI: 10.1021/Np50098A017  0.378
1993 Wickramaratne DB, Pengsuparp T, Mar W, Chai HB, Chagwedera TE, Beecher CW, Farnsworth NR, Kinghorn AD, Pezzuto JM, Cordell GA. Novel antimitotic dibenzocyclo-octadiene lignan constituents of the stem bark of Steganotaenia araliacea. Journal of Natural Products. 56: 2083-90. PMID 8133298 DOI: 10.1021/Np50102A009  0.467
1993 Topçu G, Öksüz S, Shieh H, Cordell GA, Pezzuto JM, Bozok-Johansson C. Cytotoxic and antibacterial sesquiterpenes from Inula graveolens Phytochemistry. 33: 407-410. DOI: 10.1016/0031-9422(93)85529-Z  0.417
1993 Afifi MS, Ahmed MM, Pezzuto JM, Douglas Kinghornt A. Cytotoxic flavonolignans and flavones from Verbascum sinaiticum leaves Phytochemistry. 34: 839-841. DOI: 10.1016/0031-9422(93)85369-3  0.395
1993 Dai J, Chai H, Pezzuto JM, Kinghorn AD, Tsauri S, Padmawinata K. Cytotoxic constituents of the roots of the indonesian medicinal plantFibraurea chloroleuca Phytotherapy Research. 7: 290-294. DOI: 10.1002/Ptr.2650070406  0.44
1993 Lin L, Lin L, Pezzuto JM, Cordell GA, Ruangrungsi N. Isogambogic acid and isomorellinol fromGarcinia hanburyi Magnetic Resonance in Chemistry. 31: 340-347. DOI: 10.1002/Mrc.1260310406  0.348
1992 Kardono LB, Angerhofer CK, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Cytotoxic and antimalarial constituents of the roots of Eurycoma longifolia. Journal of Natural Products. 54: 1360-7. PMID 1800638 DOI: 10.1021/np50077a020  0.32
1992 Shieh HL, Pezzuto JM, Cordell GA. Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives. Chemico-Biological Interactions. 81: 35-55. PMID 1730147 DOI: 10.1016/0009-2797(92)90025-G  0.424
1992 Kaneda N, Pezzuto JM, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, L. cytotoxic triterpenes from Sandoricum koetjape stems Journal of Natural Products. 55: 654-659. PMID 1517737 DOI: 10.1021/Np50083A016  0.477
1992 Kaneda N, Chai H, Pezzuto JM, Kinghorn AD, Farnsworth NR, Tuchinda P, Udchachon J, Santisuk T, Reutrakul V. Cytotoxic activity of cardenolides from Beaumontia brevituba stems Planta Medica. 58: 429-431. PMID 1470666 DOI: 10.1055/S-2006-961506  0.359
1992 Angerhofer CK, Pezzuto JM, König GM, Wright AD, Sticher O. Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra. Journal of Natural Products. 55: 1787-9. PMID 1294700 DOI: 10.1021/Np50090A014  0.442
1992 König G, Wright A, Sticker O, Angerhofer C, Pezzuto J. Bioactive Marine Natural Products: Antimalarial Activity of Sponge Metabolites Planta Medica. 58: 585-585. DOI: 10.1055/S-2006-961572  0.328
1992 Pezzuto JM, Mar W, Lin L, Cordell GA, Neszmélyi A, Wagner H. Budmunchiamines D–I from Albizia amara Phytochemistry. 31: 1795-1800. DOI: 10.1016/0031-9422(92)83150-W  0.335
1992 Lin L, Topcu G, Lotter H, Ruangrungsi N, Wagner H, Pezzuto JM, Cordell GA. Wrightiadione from Wrightia tomentosa Phytochemistry. 31: 4333-4335. DOI: 10.1016/0031-9422(92)80469-U  0.383
1992 Lin L, Ruangrungsi N, Cordell GA, Shieh H, You M, Pezzuto JM. 6-Deoxyclitoriacetal from Clitoria macrophylla Phytochemistry. 31: 4329-4331. DOI: 10.1016/0031-9422(92)80468-T  0.407
1991 Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnsworth NR, Santisuk T, Tuchinda P, Udchachon J, Reutrakul V. Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots Journal of Natural Products. 54: 196-206. PMID 2045815 DOI: 10.1021/Np50073A019  0.468
1991 Kardono LB, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia. Journal of Natural Products. 53: 1447-55. PMID 1965200 DOI: 10.1021/Np50072A008  0.475
1991 Duh CY, Kinghorn AD, Pezzuto JM. Cell-cycle specific cytotoxicity mediated by stizophyllin (2 alpha,3 beta,12 beta-trihydroxypregna-4,7,16-trien-20-one), a novel electrophilic pregnane isolated from Stizophyllum riparium. Chemico-Biological Interactions. 80: 43-56. PMID 1913978 DOI: 10.1016/0009-2797(91)90030-B  0.355
1991 Cordell GA, Beecher CW, Pezzuto JM. Can ethnopharmacology contribute to the development of new anticancer drugs? Journal of Ethnopharmacology. 32: 117-33. PMID 1881151 DOI: 10.1016/0378-8741(91)90110-Y  0.381
1991 Pezzuto JM, Che CT, McPherson DD, Zhu JP, Topcu G, Erdelmeier CA, Cordell GA. DNA as an affinity probe useful in the detection and isolation of biologically active natural products. Journal of Natural Products. 54: 1522-30. PMID 1812211 DOI: 10.1021/Np50078A006  0.406
1991 Ngassapa OD, Soejarto DD, Che CT, Pezzuto JM, Farnsworth NR. New cytotoxic lupane lactones from Kokoona ochracea Journal of Natural Products. 54: 1353-1359. PMID 1800637 DOI: 10.1021/Np50077A019  0.467
1991 Mar W, Tan GT, Cordell GA, Pezzuto JM, Jurcic K, Offermann F, Redl K, Steinke B, Wagner H. Biological activity of novel macrocyclic alkaloids (budmunchiamines) from Albizia amara detected on the basis of interaction with DNA. Journal of Natural Products. 54: 1531-42. PMID 1725878 DOI: 10.1021/Np50078A007  0.342
1991 Tan GT, Pezzuto JM, Kinghorn AD, Hughes SH. Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Journal of Natural Products. 54: 143-54. PMID 1710653  0.311
1991 Konig GM, Wright AD, Sticher O, Jurcic K, Offermann F, Redl K, Wagner H, Angerhofer CK, Pezzuto JM. Structure elucidation and biological activity of secondary metabolites from marine red and brown algae Planta Medica. 57: A5. DOI: 10.1055/S-2006-960242  0.345
1991 Fullas F, Hussain RA, Bordas E, Pezzuto JM, Soejarto DD, Kinghorn AD. Gaudichaudiosides A-E, five novel diterpene glycoside constituents from the sweet-tasting plant, Baccharis gaudichaudiana Tetrahedron. 47: 8515-8522. DOI: 10.1016/S0040-4020(01)82394-2  0.344
1991 Tuchinda P, Udchachon J, Reutrakul V, Santisuk T, Taylor WC, Farnsworth NR, Pezzuto JM, Kinghorn AD. Bioactive butenolides from Melodorum fruticosum Phytochemistry. 30: 2685-2689. DOI: 10.1016/0031-9422(91)85123-H  0.424
1991 Dai J, Kardono LB, Tsauri S, Padmawinata K, Pezzuto JM, Kinghorn AD. Phenylacetic acid derivatives and a thioamide glycoside fromEntada phaseoloides Phytochemistry. 30: 3749-3752. DOI: 10.1016/0031-9422(91)80102-7  0.393
1990 Choi YH, Hussain RA, Pezzuto JM, Kinghorn AD, Morton JF. Abrusosides A-D, four novel sweet-tasting triterpene glycosides from the leaves of Abrus precatorius. Journal of Natural Products. 52: 1118-27. PMID 2691636 DOI: 10.1021/Np50065A032  0.321
1990 Blaskó G, Shieh HL, Pezzuto JM, Cordell GA. 13C-nmr spectral assignment and evaluation of the cytotoxic potential of rotenone. Journal of Natural Products. 52: 1363-6. PMID 2614425 DOI: 10.1021/Np50066A035  0.356
1990 Kigodi PG, Blaskó G, Thebtaranonth Y, Pezzuto JM, Cordell GA. Spectroscopic and biological investigation of nimbolide and 28-deoxonimbolide from Azadirachta indica. Journal of Natural Products. 52: 1246-51. PMID 2614419 DOI: 10.1021/Np50066A008  0.436
1990 Bavovada R, Blaskó G, Shieh HL, Pezzuto JM, Cordell GA. Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum. Planta Medica. 56: 380-2. PMID 2236293 DOI: 10.1055/S-2006-960988  0.335
1990 Pezzuto J, Beattie C, Lowell K, Mar W, Swanson S, Reutrakul V, Kinghorn A, Farnsworth N. Evaluation of the Cytotoxic Potential of Natural Products Employing a Battery of Human Cancer Cell Lines Planta Medica. 56: 673-673. DOI: 10.1055/S-2006-961340  0.336
1990 Kaneda N, Pezzuto JM, Soejarto DD, Kinghorn AD, Farnsworth NR, Tuchinda P, Udchachon J, Santisuk T, Reutrakul V. New cytotoxic flavonoids from Muntingia calabura roots Planta Medica. 56: 672-673. DOI: 10.1055/S-2006-961339  0.329
1989 Pezzuto JM, Swanson SM, Mar W, Che CT, Cordell GA, Fong HH. Evaluation of the mutagenic and cytostatic potential of aristolochic acid (3,4-methylenedioxy-8-methoxy-10-nitrophenanthrene-1-carboxylic acid) and several of its derivatives. Mutation Research. 206: 447-54. PMID 3060719 DOI: 10.1016/0165-1218(88)90052-3  0.421
1989 Swanson SM, Jiang JX, Chang YS, De Souza NJ, Pezzuto JM. A rapid and sensitive bioassay involving cultured rat glioma cells to screen for substances capable of elevating intracellular cyclic AMP concentration. Journal of Natural Products. 51: 929-36. PMID 2849641 DOI: 10.1021/Np50059A019  0.353
1989 Jonathan LT, Che CT, Pezzuto JM, Fong HH, Farnsworth NR. 7-O-methylhorminone and other cytotoxic diterpene quinones from Lepechinia bullata. Journal of Natural Products. 52: 571-5. PMID 2778450 DOI: 10.1021/Np50063A016  0.418
1989 Jayasuriya H, McChesney JD, Swanson SM, Pezzuto JM. Antimicrobial and cytotoxic activity of rottlerin-type compounds from Hypericum drummondii. Journal of Natural Products. 52: 325-31. PMID 2746258 DOI: 10.1021/Np50062A018  0.468
1988 Lam LK, Garg PK, Swanson SM, Pezzuto JM. Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole. Journal of Pharmaceutical Sciences. 77: 393-5. PMID 3411459 DOI: 10.1002/Jps.2600770507  0.439
1988 Nanayakkara NP, Hussain RA, Pezzuto JM, Soejarto DD, Kinghorn AD. An intensely sweet dihydroflavonol derivative based on a natural product lead compound. Journal of Medicinal Chemistry. 31: 1250-3. PMID 3373494 DOI: 10.1021/Jm00401A030  0.399
1988 Choi YH, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant anticancer agents, XLVI. Cytotoxic casbane-type constituents of Agrostistachys hookeri. Journal of Natural Products. 51: 110-6. PMID 3373221 DOI: 10.1021/Np50055A016  0.415
1988 Compadre CM, Hussain RA, Nanayakkara NPD, Pezzuto JM, Kinghorn AD. Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside a, and rubusoside Biomedical &Amp; Environmental Mass Spectrometry. 15: 211-222. PMID 3370361 DOI: 10.1002/Bms.1200150405  0.327
1988 Kim J, Pezzuto JM, Soejarto DD, Lang FA, Kinghorn AD. Polypodoside A, an intensely sweet constituent of the rhizomes of Polypodium glycyrrhiza Journal of Natural Products. 51: 1166-1172. PMID 3236009 DOI: 10.1021/Np50060A019  0.319
1987 Nanayakkara NPD, Klocke JA, Compadre CM, Hussain RA, Pezzuto JM, Kinghorn AD. Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside A Journal of Natural Products. 50: 434-441. PMID 3668559 DOI: 10.1021/Np50051A015  0.401
1987 Wong SM, Konno C, Oshima Y, Pezzuto JM, Fong HH, Farnsworth NR. Irisones A and B: two new isoflavones from Iris missouriensis. Journal of Natural Products. 50: 178-80. PMID 3655793 DOI: 10.1021/Np50050A008  0.358
1987 Duh CY, Pezzuto JM, Kinghorn AD, Leung SL, Farnsworth NR. Plant anticancer agents XLIV. Cytotoxic constituents from Stizophyllum riparium. Journal of Natural Products. 50: 63-74. PMID 3598599 DOI: 10.1021/Np50049A010  0.317
1986 Hussain RA, Kim J, Hu TW, Pezzuto JM, Soejarto DD, Kinghorn AD. Isolation of a Highly Sweet Constituent from Cinnamomum osmophloeum Leaves1. Planta Medica. 403-4. PMID 17345354 DOI: 10.1055/S-2007-969199  0.361
1986 Wong SM, Pezzuto JM, Fong HH, Farnsworth NR. Isolation and characterization of a new triterpene from Iris missouriensis. Journal of Natural Products. 49: 330-3. PMID 3734815 DOI: 10.1021/Np50044A024  0.322
1986 Wong SM, Oshima Y, Pezzuto JM, Fong HH, Farnsworth NR. Plant anticancer agents XXXIX: Triterpenes from Iris missouriensis (Iridaceae). Journal of Pharmaceutical Sciences. 75: 317-20. PMID 3701620 DOI: 10.1002/Jps.2600750324  0.422
1986 Pezzuto JM, Dhammika Nanayakkara NP, Compadre CM, Swanson SM, Kinghorn AD, Guenthner TM, Sparnins VL, Lam LKT. Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S-transferase in mice Mutation Research/Genetic Toxicology. 169: 93-103. PMID 3512998 DOI: 10.1016/0165-1218(86)90088-1  0.39
1986 Choi Y, Kim J, Pezzuto J, Kinghorn A, Farnsworth N, Letter H, Wagner H. Agrostistachin, a novel cytotoxic macrocyclic diterpene from Tetrahedron Letters. 27: 5795-5798. DOI: 10.1016/S0040-4039(00)85329-0  0.363
1985 Fang X, Nanayakkara NP, Phoebe CH, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant Anticancer Agents XXXVII. Constituents of Amanoa oblongifolia1. Planta Medica. 51: 346-7. PMID 17340533 DOI: 10.1055/S-2007-969511  0.373
1985 Pezzuto JM, Compadre CM, Swanson SM, Nanayakkara D, Kinghorn AD. Metabolically activated steviol, the aglycone of stevioside, is mutagenic Proceedings of the National Academy of Sciences of the United States of America. 82: 2478-2482. PMID 3887402 DOI: 10.1073/Pnas.82.8.2478  0.346
1985 Compadre CM, Pezzuto JM, Kinghorn AD, Kamath SK. Hernandulcin: An intensely sweet compound discovered by review of ancient literature Science. 227: 417-419. PMID 3880922 DOI: 10.1126/Science.3880922  0.356
1985 Wong SM, Pezzuto JM, Fong HH, Farnsworth NR. Isolation, structural elucidation, and chemical synthesis of 2-hydroxy-3-octadecyl-5-methoxy-1,4-benzoquinone (irisoquin), a cytotoxic constituent of Iris missouriensis. Journal of Pharmaceutical Sciences. 74: 1114-6. PMID 3841153 DOI: 10.1002/Jps.2600741023  0.449
1985 McPherson DD, Che C, Cordell GA, Doel Soejarto D, Pezzuto JM, Fong HH. Diterpenoids from Caesalpinia pulcherrima Phytochemistry. 25: 167-170. DOI: 10.1016/S0031-9422(00)94522-9  0.305
1985 Fiebig M, Pezzuto JM, Soejarto DD, Kinghorn AD. Koenoline, a further cytotoxic carbazole alkaloid from Murraya koenigii Phytochemistry. 24: 3041-3043. DOI: 10.1016/0031-9422(85)80052-2  0.403
1984 Ji-Xian G, Handa SS, Pezzuto JM, Kinghorn AD, Farnsworth NR. Plant Anticancer Agents XXXIII. Constituents of Passerina vulgaris1. Planta Medica. 50: 264-5. PMID 17340308 DOI: 10.1055/S-2007-969695  0.436
1984 Arisawa M, Pezzuto JM, Kinghorn AD, Cordell GA, Farnsworth NR. Plant anticancer agents. XXX: Cucurbitacins from Ipomopsis aggregata (Polemoniaceae). Journal of Pharmaceutical Sciences. 73: 411-3. PMID 6546946 DOI: 10.1002/Jps.2600730335  0.325
1984 Arisawa M, Pezzuto JM, Bevelle C, Cordell GA. Potential anticancer agents XXXI. N-demethylation of fagaronine. Journal of Natural Products. 47: 453-8. PMID 6481359 DOI: 10.1021/Np50033A009  0.412
1983 Pezzuto JM, Antosiak SK, Messmer WM, Slaytor MB, Honig GR. Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids. Chemico-Biological Interactions. 43: 323-39. PMID 6337734 DOI: 10.1016/0009-2797(83)90116-3  0.329
1983 McPherson DD, Cordell GA, Soejarto DD, Pezzuto JM, Fong HHS. Peltogynoids and homoisoflavonoids from Caesalpinia pulcherrima Phytochemistry. 22: 2835-2838. DOI: 10.1016/S0031-9422(00)97708-2  0.443
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