Year |
Citation |
Score |
2022 |
Roberts DD, McLaughlin MG. Diastereoselective access to substituted oxetanes hydrosilylation-iodocyclisation of homopropargylic alcohols. Chemical Communications (Cambridge, England). PMID 35792361 DOI: 10.1039/d2cc03339a |
0.347 |
|
2022 |
Basson AJ, Halcovitch NR, McLaughlin MG. Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35642626 DOI: 10.1002/chem.202201107 |
0.323 |
|
2021 |
Roberts DD, McLaughlin MG. Regioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds. Organic Letters. 23: 4463-4467. PMID 34018758 DOI: 10.1021/acs.orglett.1c01398 |
0.358 |
|
2021 |
Basson AJ, McLaughlin MG. Sustainable Access to 5-Amino-Oxazoles and Thiazoles via Calcium-Catalyzed Elimination-Cyclization with Isocyanides. Chemsuschem. PMID 33605021 DOI: 10.1002/cssc.202100225 |
0.332 |
|
2020 |
Patel NR, Nawrat CC, McLaughlin M, Xu Y, Huffman MA, Yang H, Li H, Whittaker AM, Andreani T, Lévesque F, Fryszkowska A, Brunskill A, Tschaen DM, Maloney KM. Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone. Organic Letters. PMID 32516536 DOI: 10.1021/Acs.Orglett.0C01431 |
0.338 |
|
2020 |
Basson AJ, McLaughlin MG. Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of -Acyliminium Ions. The Journal of Organic Chemistry. 85: 5615-5628. PMID 32208694 DOI: 10.1021/Acs.Joc.0C00482 |
0.335 |
|
2020 |
Britten TK, McLaughlin MG. Brønsted Acid Catalyzed Peterson Olefinations. The Journal of Organic Chemistry. 85: 301-305. PMID 31775003 DOI: 10.1021/Acs.Joc.9B02489 |
0.392 |
|
2019 |
Basson AJ, McLaughlin MG. Functionalisation of isoindolinones via a calcium catalysed Hosomi-Sakurai allylation. Chemical Communications (Cambridge, England). 55: 8317-8320. PMID 31257381 DOI: 10.1039/C9Cc02450F |
0.34 |
|
2019 |
Le Bihan YV, Lanigan RM, Atrash B, McLaughlin MG, Velupillai S, Malcolm AG, England KS, Ruda GF, Mok NY, Tumber A, Tomlin K, Saville H, Shehu E, McAndrew C, Carmichael L, et al. C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. European Journal of Medicinal Chemistry. 177: 316-337. PMID 31158747 DOI: 10.1016/J.Ejmech.2019.05.041 |
0.62 |
|
2018 |
Kiely-Collins HJ, Sechi I, Brennan PE, McLaughlin MG. Mild, calcium catalysed Beckmann rearrangements. Chemical Communications (Cambridge, England). 54: 654-657. PMID 29300400 DOI: 10.1039/C7Cc09491D |
0.5 |
|
2018 |
Kerr WJ, McLaughlin M, Paterson LC, Pearson CM. Total synthesis 2-epi-α-cedren-3-one via a cobalt-catalysed Pauson-Khand reaction Tetrahedron. 74: 5062-5068. DOI: 10.1016/J.Tet.2018.06.032 |
0.408 |
|
2017 |
Peng F, Chen Y, Chen CY, Dormer PG, Kassim A, McLaughlin M, Reamer RA, Sherer EC, Song ZJ, Tan L, Tudge MT, Wan B, Chung JYL. Asymmetric Formal Synthesis of the Long-acting DPP-4 Inhibitor Omarigliptin. The Journal of Organic Chemistry. PMID 28776371 DOI: 10.1021/Acs.Joc.7B01467 |
0.415 |
|
2016 |
Bavetsias V, Lanigan RM, Ruda GF, Atrash B, McLaughlin MG, Tumber A, Mok NY, Le Bihan YV, Dempster S, Boxall KJ, Jeganathan F, Hatch SB, Savitsky P, Velupillai S, Krojer T, et al. 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. Journal of Medicinal Chemistry. PMID 26741168 DOI: 10.1021/Acs.Jmedchem.5B01635 |
0.635 |
|
2016 |
Mullens P, Cleator E, McLaughlin M, Bishop B, Edwards J, Goodyear A, Andreani T, Jin Y, Kong J, Li H, Williams M, Zacuto M. Two Approaches to the Chemical Development and Large-Scale Preparation of a Pyrimidyl Tetrazole Intermediate Organic Process Research & Development. 20: 1075-1087. DOI: 10.1021/Acs.Oprd.6B00136 |
0.414 |
|
2016 |
Williams MJ, Chen Q, Codan L, Dermenjian RK, Dreher S, Gibson AW, He X, Jin Y, Keen SP, Lee AY, Lieberman DR, Lin W, Liu G, McLaughlin M, Reibarkh M, et al. Process Development of the HCV NS5B Site D Inhibitor MK-8876 Organic Process Research and Development. 20: 1227-1238. DOI: 10.1021/Acs.Oprd.5B00405 |
0.308 |
|
2015 |
McLaughlin MG, McAdam CA, Cook MJ. MIDA-vinylsilanes: selective cross-couplings and applications to the synthesis of functionalized stilbenes. Organic Letters. 17: 10-3. PMID 25513732 DOI: 10.1021/Ol503065A |
0.645 |
|
2015 |
McAdam CA, McLaughlin MG, Cook MJ. An alkyne hydrosilylation-Hiyama coupling approach to highly functionalised 1,3-dienes Organic Chemistry Frontiers. 2: 510-514. DOI: 10.1039/C5Qo00002E |
0.628 |
|
2015 |
McAdam CA, McLaughlin MG, Cook MJ. ChemInform Abstract: An Alkyne Hydrosilylation-Hiyama Coupling Approach to Highly Functionalized 1,3-Dienes. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201540079 |
0.574 |
|
2014 |
McLaughlin MG, Cook MJ. Highly diastereoselective hydrosilylations of allylic alcohols. Chemical Communications (Cambridge, England). 50: 3501-4. PMID 24557001 DOI: 10.1039/C4Cc00138A |
0.628 |
|
2013 |
Johnston AJ, McLaughlin MG, Reid JP, Cook MJ. NaH mediated isomerisation-allylation reaction of 1,3-substituted propenols. Organic & Biomolecular Chemistry. 11: 7662-6. PMID 24108362 DOI: 10.1039/C3Ob41857J |
0.635 |
|
2013 |
McAdam CA, McLaughlin MG, Johnston AJ, Chen J, Walter MW, Cook MJ. Platinum catalysed hydrosilylation of propargylic alcohols. Organic & Biomolecular Chemistry. 11: 4488-502. PMID 23715614 DOI: 10.1039/C3Ob40496J |
0.66 |
|
2013 |
McLaughlin M, Belyk K, Chen CY, Linghu X, Pan J, Qian G, Reamer RA, Xu Y. Practical asymmetric synthesis of a chiral piperazinone derivative Organic Process Research and Development. 17: 1052-1060. DOI: 10.1021/Op400150W |
0.37 |
|
2012 |
Zhong YL, Gauthier DR, Shi YJ, McLaughlin M, Chung JY, Dagneau P, Marcune B, Krska SW, Ball RG, Reamer RA, Yasuda N. Synthesis of antifungal glucan synthase inhibitors from enfumafungin. The Journal of Organic Chemistry. 77: 3297-310. PMID 22423625 DOI: 10.1021/Jo300046V |
0.471 |
|
2012 |
McLaughlin MG, Cook MJ. Domino alkene-isomerization-Claisen rearrangement strategy to substituted allylsilanes. The Journal of Organic Chemistry. 77: 2058-63. PMID 22235747 DOI: 10.1021/Jo202560G |
0.661 |
|
2012 |
Flanagan JCA, Dornan LM, McLaughlin MG, McCreanor NG, Cook MJ, Muldoon MJ. The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols Green Chemistry. 14: 1281. DOI: 10.1039/C2Gc35062A |
0.641 |
|
2012 |
Flanagan JCA, Dornan LM, McLaughlin MG, McCreanor NG, Cook MJ, Muldoon MJ. ChemInform Abstract: The Synthesis of N-Heterocycles via Copper/TEMPO Catalyzed Aerobic Oxidation of Amino Alcohols. Cheminform. 43: no-no. DOI: 10.1002/CHIN.201240132 |
0.613 |
|
2011 |
McLaughlin MG, Cook MJ. PtCl2/XPhos: a highly efficient and readily available catalyst for the hydrosilylation of propargylic alcohols. Chemical Communications (Cambridge, England). 47: 11104-6. PMID 21909537 DOI: 10.1039/C1Cc14433B |
0.651 |
|
2005 |
Amato JS, Chung JY, Cvetovich RJ, Gong X, McLaughlin M, Reamer RA. Synthesis of 1-tert-butyl-4-chloropiperidine: generation of an N-tert-butyl group by the reaction of a dimethyliminium salt with methylmagnesium chloride. The Journal of Organic Chemistry. 70: 1930-3. PMID 15730326 DOI: 10.1021/Jo048047G |
0.423 |
|
2001 |
Kerr WJ, McLaughlin M, Morrison AJ, Pauson PL. Formal total synthesis of (+/-)-alpha- and beta-cedrene by preparation of cedrone. Construction of the tricyclic carbon skeleton by the use of a highly efficient intramolecular Khand annulation. Organic Letters. 3: 2945-8. PMID 11554814 DOI: 10.1021/Ol016054A |
0.333 |
|
1986 |
Deutsch HM, Gelbaum LT, McLaughlin M, Fleischmann TJ, Earnhart LL, Haugwitz RD, Zalkow LH. Synthesis of congeners and prodrugs of the benzene maleimide photoadduct mitindomide as potential antitumor agents. 2. Journal of Medicinal Chemistry. 29: 2164-70. PMID 3783577 DOI: 10.1021/Jm00161A006 |
0.347 |
|
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