Jose M Otero - Publications

Affiliations: 
2003-2007 CACTUS University of Santiago de Compostela, Santiago de Compostela, Galicia, Spain 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Reza D, Balo R, Otero JM, Fletcher AM, García-Fandino R, Sánchez-Pedregal VM, Davies SG, Estévez RJ, Estévez JC. β-Peptides incorporating polyhydroxylated cyclohexane β-amino acid: synthesis and conformational study. Organic & Biomolecular Chemistry. PMID 37840474 DOI: 10.1039/d3ob00906h  0.708
2020 Otero JM, Estévez AM, Estévez JC, Fleet GWJ, Estévez RJ. Highly functionalized cyclic and bicyclic β−amino acids from sugar β−nitroesters Tetrahedron. 76: 130837. DOI: 10.1016/J.Tet.2019.130837  0.739
2016 Liu Z, Yoshihara A, Kelly C, Heap JT, Marqvorsen MH, Jenkinson SF, Wormald MR, Otero JM, Estévez A, Kato A, Fleet GW, Estévez RJ, Izumori K. 6-Deoxyhexoses from l-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27439720 DOI: 10.1002/Chem.201602482  0.723
2016 Kelly CL, Liu Z, Yoshihara A, Jenkinson SF, Wormald MR, Otero JM, Estévez AM, Kato A, Marqvorsen MH, Fleet GW, Estevez RJ, Izumori K, Heap JT. Synthetic chemical inducers and genetic decoupling enable orthogonal control of the rhaBAD promoter. Acs Synthetic Biology. PMID 27247275 DOI: 10.1021/Acssynbio.6B00030  0.715
2015 Tizón L, Maneiro M, Peón A, Otero JM, Lence E, Poza S, van Raaij MJ, Thompson P, Hawkins AR, González-Bello C. Irreversible covalent modification of type I dehydroquinase with a stable Schiff base. Organic & Biomolecular Chemistry. 13: 706-16. PMID 25370445 DOI: 10.1039/C4Ob01782J  0.302
2013 Lence E, Tizón L, Otero JM, Peón A, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, González-Bello C. Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids. Acs Chemical Biology. 8: 568-77. PMID 23198883 DOI: 10.1021/Cb300493S  0.343
2013 Soengas RG, Otero JM, Estevez AM, Rauter AP, Cachatra V, Estevez JC, Estevez RJ. ChemInform Abstract: Key Routes for the Transformation of Sugars into Carbasugars and Related Compounds Cheminform. 44: no-no. DOI: 10.1002/CHIN.201318255  0.679
2012 Otero JM, Noël AJ, Guardado-Calvo P, Llamas-Saiz AL, Wende W, Schierling B, Pingoud A, van Raaij MJ. High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 1139-48. PMID 23027736 DOI: 10.1107/S1744309112033982  0.315
2012 Otero JM, Barcia JC, Salas CO, Thomas P, Estévez JC, Estévez RJ. Studies on the Michael addition of naphthoquinones to sugar nitro olefins: first synthesis of polyhydroxylated hexahydro-11H-benzo[a]carbazole-5,6-diones and hexahydro-11bH-benzo[b]carbazole-6,11-diones Tetrahedron. 68: 1612-1621. DOI: 10.1016/J.Tet.2011.11.072  0.762
2012 Otero JM, Fernández F, Estévez JC, Nash R, Estévez RJ. A Nitro Sugar‐Mediated Stereocontrolled Synthesis of β2‐Amino Acids: Synthesis of a Polyhydroxylated trans‐2‐Amino­cyclohexanecarboxylic Acid European Journal of Organic Chemistry. 2012: 2969-2979. DOI: 10.1002/Ejoc.201200103  0.736
2011 Knijnenburg AD, Kapoerchan VV, Grotenbreg GM, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, Ravensbergen B, Nibbering PH, van der Marel GA, Overkleeft HS, Overhand M. Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives. Bioorganic & Medicinal Chemistry. 19: 3402-9. PMID 21561781 DOI: 10.1016/J.Bmc.2011.04.031  0.38
2011 Sussman F, Otero JM, Villaverde MC, Castro M, Domínguez JL, González-Louro L, Estévez RJ, Estévez JC. On a possible neutral charge state for the catalytic dyad in β-secretase when bound to hydroxyethylene transition state analogue inhibitors. Journal of Medicinal Chemistry. 54: 3081-5. PMID 21452857 DOI: 10.1021/Jm101568Y  0.677
2011 van der Knaap M, Lageveen LT, Busscher HJ, Mars-Groenendijk R, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Evaluation of readily accessible azoles as mimics of the aromatic ring of D-phenylalanine in the turn region of gramicidin S. Chemmedchem. 6: 840-7. PMID 21400662 DOI: 10.1002/Cmdc.201000539  0.313
2011 Knijnenburg AD, Tuin AW, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Exploring the conformational and biological versatility of β-turn-modified gramicidin S by using sugar amino acid homologues that vary in ring size. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 3995-4004. PMID 21365698 DOI: 10.1002/Chem.201002895  0.361
2010 Peón A, Otero JM, Tizón L, Prazeres VF, Llamas-Saiz AL, Fox GC, van Raaij MJ, Lamb H, Hawkins AR, Gago F, Castedo L, González-Bello C. Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids. Chemmedchem. 5: 1726-33. PMID 20815012 DOI: 10.1002/Cmdc.201000281  0.324
2010 Kapoerchan VV, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Ferraces-Casais P, Llamas-Saiz AL, van Raaij MJ, van Doorn J, van der Marel GA, Overkleeft HS, Overhand M. Gramicidin S derivatives containing cis- and trans-morpholine amino acids (MAAs) as turn mimetics. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 4259-65. PMID 20209520 DOI: 10.1002/Chem.200902984  0.347
2010 Prazeres VF, Tizón L, Otero JM, Guardado-Calvo P, Llamas-Saiz AL, van Raaij MJ, Castedo L, Lamb H, Hawkins AR, González-Bello C. Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues. Journal of Medicinal Chemistry. 53: 191-200. PMID 19911771 DOI: 10.1021/Jm9010466  0.308
2010 Estévez AM, Soengas RG, Otero JM, Estévez JC, Nash RJ, Estévez RJ. Studies on the transformation of nitrosugars into iminosugars III: synthesis of (2R,3R,4R,5R,6R)-2-(hydroxymethyl)azepane-3,4,5,6-tetraol and (2R,3R,4R,5R,6S)-2-(hydroxymethyl)azepane-3,4,5,6-tetraol Tetrahedron Asymmetry. 21: 21-26. DOI: 10.1016/J.Tetasy.2009.12.006  0.729
2009 van der Knaap M, Engels E, Busscher HJ, Otero JM, Llamas-Saiz AL, van Raaij MJ, Mars-Groenendijk RH, Noort D, van der Marel GA, Overkleeft HS, Overhand M. Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues. Bioorganic & Medicinal Chemistry. 17: 6318-28. PMID 19674904 DOI: 10.1016/J.Bmc.2009.07.042  0.347
2009 Burck S, van Assema SG, Lastdrager B, Slootweg JC, Ehlers AW, Otero JM, Dacunha-Marinho B, Llamas-Saiz AL, Overhand M, van Raaij MJ, Lammertsma K. Bisphosphine-functionalized cyclic decapeptides based on the natural product Gramicidin S: a potential scaffold for transition-metal coordination. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 8134-45. PMID 19603436 DOI: 10.1002/Chem.200901127  0.362
2008 Otero JM, Estévez AM, Soengas RG, Estévez JC, Nash RJ, Fleet GWJ, Estévez RJ. Studies on the transformation of nitrosugars into branched chain iminosugars. Part II: Synthesis of (3R,4R,5R,6S)-2,2-bis(hydroxymethyl)azepane-3,4,5,6-tetraol Tetrahedron Asymmetry. 19: 2443-2446. DOI: 10.1016/J.Tetasy.2008.10.027  0.744
2007 Otero JM, Soengas RG, Estévez JC, Estévez RJ, Watkin DJ, Evinson EL, Nash RJ, Fleet GW. Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino-pentanols. Organic Letters. 9: 623-6. PMID 17286369 DOI: 10.1021/Ol062887V  0.744
2007 Barcia JC, Otero JM, Estévez JC, Estévez RJ. Preliminary Studies on the Michael Addition of Quinones to Nitroolefins: (6bR,10aS)-7,8,9,10,10a,11-Hexahydro-6bH-benzo[a]carbazole-5,6-diones, (4aR,11bS)-1,2,3,4,4a,5-Hexahydro-11bH-benzo[b]carbazole-6,11-diones, and 1,2,3,4-Tetrahydro-5H-benzo[b]carbazole-6,11-diones Synlett. 2007: 1399-1402. DOI: 10.1055/S-2007-980356  0.701
2006 Otero JM, Estévez JC, Sussman F, Villaverde MC, Estévez RJ. Total synthesis of (5S,6S)-6-amino-2,8-dimethylnonan-5-ol and (5S,6S)-6-amino-7-cyclohexyl-2-methylheptan-5-ol Arkivoc. 2007. DOI: 10.3998/Ark.5550190.0008.434  0.723
2006 Fernández F, Otero JM, Estévez JC, Estévez RJ. Preliminary studies on a novel synthesis of β-amino acids: stereocontrolled transformation of d- and l-glyceraldehyde into 3-amino-2-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)propanoic acids Tetrahedron-Asymmetry. 17: 3063-3066. DOI: 10.1016/J.Tetasy.2006.11.037  0.756
2005 Otero JM, Fernández F, Estévez JC, Estévez RJ. Preliminary studies on the synthesis of rancinamycins from nitrosugars: first total synthesis of (3S,4S,5S,6R)-5-benzyloxy-6-hydroxy-3,4-(isopropylidendioxy)-cyclohex-1-enecarbaldehyde Tetrahedron-Asymmetry. 16: 4045-4049. DOI: 10.1016/J.Tetasy.2005.10.044  0.765
2005 Otero JM, Barcia JC, Estévez JC, Estévez RJ. Preliminary studies on the incorporation of sugars into naphthoquinones: synthesis of (1R,2S,3S,4R,4aS,11bS)-2-(benzyloxy)-1,2,3,4,4a,5-hexahydro-1,3,4-trihydroxy-11bH-benzo[b]carbazole-6,11-dione Tetrahedron-Asymmetry. 16: 11-14. DOI: 10.1016/J.Tetasy.2004.11.045  0.763
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