| Year |
Citation |
Score |
| 2024 |
Liu S, Yeh C, Reavill C, Jones B, Zou Y, Hai Y. Molecular and structural basis for Cγ-C bond formation by PLP-dependent enzyme Fub7. Angewandte Chemie (International Ed. in English). e202317161. PMID 38308582 DOI: 10.1002/anie.202317161 |
0.338 |
|
| 2023 |
Jenner M, Hai Y, Nguyen HH, Passmore M, Skyrud W, Kim J, Garg NK, Zhang W, Ogorzalek Loo RR, Tang Y. Elucidating the molecular programming of a nonlinear non-ribosomal peptide synthetase responsible for fungal siderophore biosynthesis. Nature Communications. 14: 2832. PMID 37198174 DOI: 10.1038/s41467-023-38484-8 |
0.474 |
|
| 2020 |
Hai Y, Jenner M, Tang Y. Fungal siderophore biosynthesis catalysed by an iterative nonribosomal peptide synthetase. Chemical Science. 11: 11525-11530. PMID 34094397 DOI: 10.1039/d0sc03627g |
0.376 |
|
| 2020 |
Hai Y, Chen M, Huang A, Tang Y. Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids. Journal of the American Chemical Society. PMID 33155797 DOI: 10.1021/jacs.0c09352 |
0.419 |
|
| 2020 |
Hai Y, Huang A, Tang Y. Biosynthesis of Amino Acid Derived α-Pyrones by an NRPS-NRPKS Hybrid Megasynthetase in Fungi. Journal of Natural Products. PMID 32159958 DOI: 10.1021/Acs.Jnatprod.9B00989 |
0.448 |
|
| 2019 |
Yee DA, Kakule TB, Cheng W, Chen M, Chong CTY, Hai Y, Hang LF, Hung YS, Liu N, Ohashi M, Okorafor IC, Song Y, Tang M, Zhang Z, Tang Y. Genome Mining of Alkaloidal Terpenoids from a Hybrid Terpene and Nonribosomal Peptide Biosynthetic Pathway. Journal of the American Chemical Society. PMID 31885262 DOI: 10.1021/Jacs.9B13046 |
0.477 |
|
| 2019 |
Hai Y, Jenner M, Tang Y. Complete Stereoinversion of l-Tryptophan by a Fungal Single-Module Nonribosomal Peptide Synthetase. Journal of the American Chemical Society. PMID 31573806 DOI: 10.1021/Jacs.9B08898 |
0.464 |
|
| 2019 |
Cai Y, Hai Y, Ohashi M, Jamieson CS, Garcia-Borras M, Houk KN, Zhou J, Tang Y. Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nature Chemistry. PMID 31332284 DOI: 10.2210/Pdb6Ix9/Pdb |
0.669 |
|
| 2019 |
Hai Y, Huang AM, Tang Y. Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi. Proceedings of the National Academy of Sciences of the United States of America. PMID 31061132 DOI: 10.1073/Pnas.1903282116 |
0.502 |
|
| 2018 |
Hai Y, Tang Y. Biosynthesis of long-chain N-acyl amide by a truncated PKS-NRPS hybrid megasynthase in fungi. Journal of the American Chemical Society. PMID 29343058 DOI: 10.1021/Jacs.7B13350 |
0.444 |
|
| 2017 |
Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN, Tang Y. SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. Nature. PMID 28902839 DOI: 10.1038/Nature23882 |
0.471 |
|
| 2017 |
Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher Iii FJ, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nature Cell Biology. PMID 28737768 DOI: 10.1038/Ncb3582 |
0.466 |
|
| 2017 |
Hai Y, Shinsky SA, Porter NJ, Christianson DW. Histone deacetylase 10 structure and molecular function as a polyamine deacetylase. Nature Communications. 8: 15368. PMID 28516954 DOI: 10.1038/Ncomms15368 |
0.545 |
|
| 2017 |
Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y. Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation. Journal of the American Chemical Society. PMID 28240554 DOI: 10.1021/Jacs.7B01089 |
0.483 |
|
| 2016 |
Hai Y, Christianson DW. Histone deacetylase 6 structure and molecular basis of catalysis and inhibition. Nature Chemical Biology. PMID 27454933 DOI: 10.1038/Nchembio.2134 |
0.528 |
|
| 2016 |
Hai Y, Christianson DW. Crystal structures of Leishmania mexicana arginase complexed with α,α-disubstituted boronic amino-acid inhibitors. Acta Crystallographica. Section F, Structural Biology Communications. 72: 300-6. PMID 27050264 DOI: 10.1107/S2053230X16003630 |
0.553 |
|
| 2015 |
Hai Y, Kerkhoven EJ, Barrett MP, Christianson DW. Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster. Biochemistry. 54: 458-71. PMID 25536859 DOI: 10.1021/Bi501366A |
0.573 |
|
| 2014 |
Hai Y, Edwards JE, Van Zandt MC, Hoffmann KF, Christianson DW. Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis. Biochemistry. 53: 4671-84. PMID 25007099 DOI: 10.1021/Bi5004519 |
0.584 |
|
| 2013 |
Hai Y, Dugery RJ, Healy D, Christianson DW. Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry. 52: 9294-309. PMID 24261485 DOI: 10.1021/Bi401352H |
0.556 |
|
| 2013 |
D'Antonio EL, Ullman B, Roberts SC, Dixit UG, Wilson ME, Hai Y, Christianson DW. Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. Archives of Biochemistry and Biophysics. 535: 163-76. PMID 23583962 DOI: 10.1016/J.Abb.2013.03.015 |
0.591 |
|
| 2012 |
D'Antonio EL, Hai Y, Christianson DW. Structure and function of non-native metal clusters in human arginase I. Biochemistry. 51: 8399-409. PMID 23061982 DOI: 10.1021/Bi301145N |
0.536 |
|
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