Patrick Fadden - Publications

Pharmacology University of Virginia, Charlottesville, VA 

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Fadden P, Huang KH, Veal JM, Steed PM, Barabasz AF, Foley B, Hu M, Partridge JM, Rice J, Scott A, Dubois LG, Freed TA, Silinski MA, Barta TE, Hughes PF, et al. Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90. Chemistry & Biology. 17: 686-94. PMID 20659681 DOI: 10.1016/J.Chembiol.2010.04.015  0.642
2009 Rice JW, Veal JM, Barabasz A, Foley B, Fadden P, Scott A, Huang K, Steed P, Hall S. Targeting of multiple signaling pathways by the Hsp90 inhibitor SNX-2112 in EGFR resistance models as a single agent or in combination with erlotinib. Oncology Research. 18: 229-42. PMID 20225761 DOI: 10.3727/096504009X12596189659240  0.705
2008 Howard BA, Sempowski GD, Scearce RM, Liao HX, Lee DM, Lam GK, Chen H, Fadden P, Haystead T, Haynes BF. Murine CD7 shares antigenic cross-reactivity with HSP-60. Hybridoma (2005). 27: 81-9. PMID 18642672 DOI: 10.1089/Hyb.2007.0553  0.577
2008 Chandarlapaty S, Sawai A, Ye Q, Scott A, Silinski M, Huang K, Fadden P, Partdrige J, Hall S, Steed P, Norton L, Rosen N, Solit DB. SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 240-8. PMID 18172276 DOI: 10.1158/1078-0432.Ccr-07-1667  0.729
2006 Steed PM, Fadden P, Hall S. A novel, selective, orally active, potent small molecule inhibitor of Hsp90 Journal of Clinical Oncology. 24: 13067-13067. DOI: 10.1200/Jco.2006.24.18_Suppl.13067  0.317
2002 Graves PR, Kwiek JJ, Fadden P, Ray R, Hardeman K, Coley AM, Foley M, Haystead TA. Discovery of novel targets of quinoline drugs in the human purine binding proteome. Molecular Pharmacology. 62: 1364-72. PMID 12435804 DOI: 10.1124/Mol.62.6.1364  0.653
2000 Mothe-Satney I, Yang D, Fadden P, Haystead TA, Lawrence JC. Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression. Molecular and Cellular Biology. 20: 3558-67. PMID 10779345 DOI: 10.1128/Mcb.20.10.3558-3567.2000  0.613
1998 Fadden P, Haystead TA, Lawrence JC. Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2. Febs Letters. 435: 105-9. PMID 9755868 DOI: 10.1016/S0014-5793(98)01047-3  0.63
1997 Brunn GJ, Fadden P, Haystead TA, Lawrence JC. The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus. The Journal of Biological Chemistry. 272: 32547-50. PMID 9405468 DOI: 10.1074/Jbc.272.51.32547  0.662
1997 Lawrence JC, Fadden P, Haystead TA, Lin TA. PHAS proteins as mediators of the actions of insulin, growth factors and cAMP on protein synthesis and cell proliferation. Advances in Enzyme Regulation. 37: 239-67. PMID 9381973 DOI: 10.1016/S0065-2571(96)00016-7  0.652
1997 Grenert JP, Sullivan WP, Fadden P, Haystead TAJ, Clark J, Mimnaugh E, Krutzsch H, Ochel HJ, Schulte TW, Sausville E, Neckers LM, Toft DO. The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation Journal of Biological Chemistry. 272: 23843-23850. PMID 9295332 DOI: 10.1074/Jbc.272.38.23843  0.419
1997 Fadden P, Haystead TA, Lawrence JC. Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes. The Journal of Biological Chemistry. 272: 10240-7. PMID 9092573 DOI: 10.1074/Jbc.272.15.10240  0.628
1996 Campos M, Fadden P, Alms G, Qian Z, Haystead TAJ. Identification of protein phosphatase-1-binding proteins by microcystin- biotin affinity chromatography Journal of Biological Chemistry. 271: 28478-28484. PMID 8910475 DOI: 10.1074/Jbc.271.45.28478  0.708
1995 Fadden P, Haystead TAJ. Quantitative and Selective Fluorophore Labeling of Phosphoserine on Peptides and Proteins: Characterization at the Attomole Level by Capillary Electrophoresis and Laser-Induced Fluorescence Analytical Biochemistry. 225: 81-88. PMID 7539987 DOI: 10.1006/Abio.1995.1111  0.309
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