David Loiselle - Related publications

Affiliations: 
2007- Pharmacology Duke University, Durham, NC 
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Dubey AR, Kinger S, Jagtap YA, Patwa SM, Kumar P, Singh S, Kumar A, Kumar A, Mishra A. Proteasome Based Molecular Strategies Against Improper Cellular Proliferation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 55: 120-143. PMID 34655466 DOI: 10.33594/000000439   
2021 Guo ZS, Qu Z. PDLIM2: Signaling pathways and functions in cancer suppression and host immunity. Biochimica Et Biophysica Acta. Reviews On Cancer. 1876: 188630. PMID 34571051 DOI: 10.1016/j.bbcan.2021.188630   
2021 Hernandez I, Cohen M. Linking cell-surface GRP78 to cancer: From basic research to clinical value of GRP78 antibodies. Cancer Letters. PMID 34637844 DOI: 10.1016/j.canlet.2021.10.004   
2021 Xu B, Guo M, Ma L, Farooqi AA, Wang L, Qiao G, Liu M, Zuo L, Ye H, Lin X, Cao S. Mere15, a novel polypeptide from Meretrix meretrix, inhibits proliferation and metastasis of human non-small cell lung cancer cells through regulating the PI3K/Akt/mTOR signaling pathway. Neoplasma. PMID 34585588 DOI: 10.4149/neo_2021_210509N628   
2021 Chen X, Song J, Wang X, Sun D, Liu Y, Jiang Y. LncRNA LINC00460: Function and mechanism in human cancer. Thoracic Cancer. PMID 34821482 DOI: 10.1111/1759-7714.14238   
2021 Lim B, Peterson CB, Davis A, Cho E, Pearson T, Liu H, Hwang M, Ueno NT, Lee J. ONC201 and an MEK Inhibitor Trametinib Synergistically Inhibit the Growth of Triple-Negative Breast Cancer Cells. Biomedicines. 9. PMID 34680527 DOI: 10.3390/biomedicines9101410   
2021 Tang X, Chang C, Mosallaei D, Woodley DT, Schönthal AH, Chen M, Li W. Heterogeneous Responses and Isoform Compensation Dim Therapeutic Window of Hsp90 ATP-Binding Inhibitors in Cancer. Molecular and Cellular Biology. MCB0045921. PMID 34871064 DOI: 10.1128/MCB.00459-21   
2021 Raman V, Van Dessel N, Hall CL, Wetherby VE, Whitney SA, Kolewe EL, Bloom SMK, Sharma A, Hardy JA, Bollen M, Van Eynde A, Forbes NS. Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases. Nature Communications. 12: 6116. PMID 34675204 DOI: 10.1038/s41467-021-26367-9   
2021 Shi Z, Gao Y, Feng L, Tian W, Dou Z, Liu C, Liu J, Xu Y, Wang Y, Yan J, Wu Q, Li J, Yang L, Zhang Z, Yang J, et al. TR35 Exerts Anti-tumor Effects by Modulating Mitogen-Activated Protein Kinase and STAT3 Signaling in Lung Cancer Cells. Frontiers in Cell and Developmental Biology. 9: 723346. PMID 34760885 DOI: 10.3389/fcell.2021.723346   
2021 Pai FC, Huang HW, Tsai YL, Tsai WC, Cheng YC, Chang HH, Chen Y. Inhibition of FABP6 Reduces Tumor Cell Invasion and Angiogenesis through the Decrease in MMP-2 and VEGF in Human Glioblastoma Cells. Cells. 10. PMID 34685761 DOI: 10.3390/cells10102782   
2021 Hao N, Zhou Y, Li Y, Zhang H, Wang B, Liu X, Ren Y, He J, Zhou C, Tang X. Clinical Value and Potential Mechanisms of Oxysterol-Binding Protein Like 3 (OSBPL3) in Human Tumors. Frontiers in Molecular Biosciences. 8: 739978. PMID 34738015 DOI: 10.3389/fmolb.2021.739978   
2021 Sun F, Liu Y, Gong T, Pan Q, Xiang T, Zhao J, Tang Y, Chen H, Han Y, Song M, Huang Y, Li H, Chen Y, Yang C, Yang J, et al. Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin. Cell Death & Disease. 12: 1093. PMID 34795209 DOI: 10.1038/s41419-021-04375-3   
2021 Tao J, Li C, Zheng Y, Wang F, Zhang M, Wu X, Chen Y, Zeng Q, Chen F, Fei W. Biological protein mediated ferroptotic tumor nanotherapeutics. Journal of Materials Chemistry. B. PMID 34730601 DOI: 10.1039/d1tb01289d   
2021 Chen J, Hu Y, Teng Y, Yang B. Increased Nuclear Transporter Importin 7 Contributes to the Tumor Growth and Correlates With CD8 T Cell Infiltration in Cervical Cancer. Frontiers in Cell and Developmental Biology. 9: 732786. PMID 34650978 DOI: 10.3389/fcell.2021.732786   
2021 Li Z, Zheng M, Zhang H, Yang X, Fan L, Fu F, Fu J, Niu R, Yan M, Zhang S. Arsenic Trioxide Promotes Tumor Progression by Inducing the Formation of PGCCs and Embryonic Hemoglobin in Colon Cancer Cells. Frontiers in Oncology. 11: 720814. PMID 34676163 DOI: 10.3389/fonc.2021.720814   
2021 Strum SW, Gyenis L, Litchfield DW. CSNK2 in cancer: pathophysiology and translational applications. British Journal of Cancer. PMID 34773100 DOI: 10.1038/s41416-021-01616-2   
2021 Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12: 5732. PMID 34593797 DOI: 10.1038/s41467-021-25872-1   
2021 Firmal P, Shah VK, Pant R, Chattopadhyay S. RING finger protein TOPORS modulates the expression of tumor suppressor SMAR1 in colorectal cancer via the TLR4-TRIF pathway. Molecular Oncology. PMID 34689394 DOI: 10.1002/1878-0261.13126   
2021 Manne RK, Agrawal Y, Malonia SK, Banday S, Edachery S, Patel A, Kumar A, Shetty P, Santra MK. FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX. The Journal of Biological Chemistry. 101253. PMID 34587475 DOI: 10.1016/j.jbc.2021.101253   
2021 Kisaki CY, Arcos SSS, Montoni F, da Silva Santos W, Calacina HM, Lima IF, Cajado-Carvalho D, Ferro ES, Nishiyama-Jr MY, Iwai LK. Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines. Toxins. 13. PMID 34437390 DOI: 10.3390/toxins13080519   
2021 Miao D, Wang Y, Jia Y, Tong J, Jiang S, Liu L. ZRANB1 enhances stem-cell-like features and accelerates tumor progression by regulating Sox9-mediated USP22/Wnt/β-catenin pathway in colorectal cancer. Cellular Signalling. 110200. PMID 34798260 DOI: 10.1016/j.cellsig.2021.110200   
2021 Zhang H, Kong L, Zhang Y, Wang C, Sun L. Transcriptome and proteome analysis of the antitumor activity of maslinic acid against pancreatic cancer cells. Aging. 13. PMID 34637398 DOI: 10.18632/aging.203623   
2021 Saha S, Zhang Y, Wilson B, Abounader R, Dutta A. A tumor suppressive long noncoding RNA, DRAIC, inhibits protein translation and induces autophagy by activating AMPK. Journal of Cell Science. PMID 34746949 DOI: 10.1242/jcs.259306   
2021 Sarrió D, Martínez-Val J, Molina-Crespo Á, Sánchez L, Moreno-Bueno G. The multifaceted roles of gasdermins in cancer biology and oncologic therapies. Biochimica Et Biophysica Acta. Reviews On Cancer. 1876: 188635. PMID 34656686 DOI: 10.1016/j.bbcan.2021.188635   
2021 Xiang Q, Dong S, Li XH. A Review of Phosphocreatine 3 Kinase δ Subtype (PI3Kδ) and Its Inhibitors in Malignancy. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 27: e932772. PMID 34625526 DOI: 10.12659/MSM.932772   
2021 Li Y, Chen J, Bolinger AA, Chen H, Liu Z, Cong Y, Brasier AR, Pinchuk IV, Tian B, Zhou J. Target-Based Small Molecule Drug Discovery Towards Novel Therapeutics for Inflammatory Bowel Diseases. Inflammatory Bowel Diseases. 27: S38-S62. PMID 34791293 DOI: 10.1093/ibd/izab190   
2021 Zhang L, Zhou A, Zhu S, Min L, Liu S, Li P, Zhang S. The role of GTPase-activating protein ARHGAP26 in human cancers. Molecular and Cellular Biochemistry. PMID 34716859 DOI: 10.1007/s11010-021-04274-3   
2021 Kim MY, Lee H, Ji SY, Kim SY, Hwangbo H, Park SH, Kim GY, Park C, Leem SH, Hong SH, Choi YH. Induction of Apoptosis by Isoalantolactone in Human Hepatocellular Carcinoma Hep3B Cells through Activation of the ROS-Dependent JNK Signaling Pathway. Pharmaceutics. 13. PMID 34683920 DOI: 10.3390/pharmaceutics13101627   
2021 Lawal B, Wang YC, Wu ATH, Huang HS. Pro-Oncogenic c-Met/EGFR, Biomarker Signatures of the Tumor Microenvironment are Clinical and Therapy Response Prognosticators in Colorectal Cancer, and Therapeutic Targets of 3-Phenyl-2H-benzo[e][1,3]-Oxazine-2,4(3H)-Dione Derivatives. Frontiers in Pharmacology. 12: 691234. PMID 34512327 DOI: 10.3389/fphar.2021.691234   
2021 Shao Q, Wang L, Yuan M, Jin X, Chen Z, Wu C. TIGIT Induces (CD3+) T Cell Dysfunction in Colorectal Cancer by Inhibiting Glucose Metabolism. Frontiers in Immunology. 12: 688961. PMID 34659197 DOI: 10.3389/fimmu.2021.688961   
2021 Jensen-Pergakes K, Tatlock J, Maegley KA, McAlpine IJ, McTigue MA, Xie T, Dillon CP, Wang Y, Yamazaki S, Spiegel N, Shi M, Nemeth A, Miller N, Hendrickson E, Lam H, et al. SAM Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance. Molecular Cancer Therapeutics. PMID 34737197 DOI: 10.1158/1535-7163.MCT-21-0620   
2021 Xu W, Liu R, Dai Y, Hong S, Dong H, Wang H. The Role of p38γ in Cancer: From review to outlook. International Journal of Biological Sciences. 17: 4036-4046. PMID 34671218 DOI: 10.7150/ijbs.63537   
2021 Poyya J, Kumar DJ, Nagendra HG, Dinesh B, Aditya Rao SJ, Joshi CG. Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator. Medical Hypotheses. 156: 110683. PMID 34583309 DOI: 10.1016/j.mehy.2021.110683   
2021 He H, Huang J, Wu S, Jiang S, Liang L, Liu Y, Liu W, Xie L, Tao Y, Jiang Y, Cong L. The roles of GTPase-activating proteins in regulated cell death and tumor immunity. Journal of Hematology & Oncology. 14: 171. PMID 34663417 DOI: 10.1186/s13045-021-01184-1   
2021 Golla U, Ehudin MA, Annageldiyev C, Zeng Z, Bastihalli Tukaramrao D, Tarren A, Date AA, Elcheva I, Berg A, Amin S, Loughran TP, Kester M, Desai D, Dovat S, Claxton D, et al. DJ4 Targets the Rho-Associated Protein Kinase Pathway and Attenuates Disease Progression in Preclinical Murine Models of Acute Myeloid Leukemia. Cancers. 13. PMID 34638385 DOI: 10.3390/cancers13194889   
2021 Garousi J, Ding H, von Witting E, Xu T, Vorobyeva A, Oroujeni M, Orlova A, Hober S, Gräslund T, Tolmachev V. Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein. Pharmaceutics. 13. PMID 34834262 DOI: 10.3390/pharmaceutics13111847   
2021 Chen Y, Zhang Z, Henson ES, Cuddihy A, Haigh K, Wang R, Haigh JJ, Gibson SB. Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth. Autophagy. 1-23. PMID 34530675 DOI: 10.1080/15548627.2021.1973338   
2021 Williams MM, Hafeez SA, Christenson JL, O'Neill KI, Hammond NG, Richer JK. Reversing an Oncogenic Epithelial-to-Mesenchymal Transition Program in Breast Cancer Reveals Actionable Immune Suppressive Pathways. Pharmaceuticals (Basel, Switzerland). 14. PMID 34832904 DOI: 10.3390/ph14111122   
2021 Ferrari AJ, Drapkin R, Gogna R. Cell Fitness: More Than Push-Ups. International Journal of Molecular Sciences. 22. PMID 33430180 DOI: 10.3390/ijms22020518   
2021 Zhang Y, Arner EN, Rizvi A, Toombs JE, Huang H, Warner SL, Foulks JM, Brekken RA. AXL inhibitor TP-0903 reduces metastasis and therapy resistance in pancreatic cancer. Molecular Cancer Therapeutics. PMID 34675118 DOI: 10.1158/1535-7163.MCT-21-0293   
2021 Kumar S, Prajapati KS, Shuaib M, Kushwaha PP, Tuli HS, Singh AK. Five-Decade Update on Chemopreventive and Other Pharmacological Potential of Kurarinone: a Natural Flavanone. Frontiers in Pharmacology. 12: 737137. PMID 34646138 DOI: 10.3389/fphar.2021.737137   
2021 Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, Xu L, Liu Z, Zhao L. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation. Cell Death & Disease. 12: 911. PMID 34615856 DOI: 10.1038/s41419-021-04213-6   
2021 Rieger I, Tsintari V, Overkamp M, Fend F, Lopez CD, Schittenhelm MM, Kampa-Schittenhelm KM. ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis. Frontiers in Molecular Biosciences. 8: 727203. PMID 34805267 DOI: 10.3389/fmolb.2021.727203   
2021 Xu Y, Chen X, Pan S, Wang ZW, Zhu X. TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer. Cell Death Discovery. 7: 299. PMID 34667152 DOI: 10.1038/s41420-021-00689-5   
2021 Feng L, Wang J, Zhang J, Diao J, He L, Fu C, Liao H, Xu X, Gao Y, Zhou C. Comprehensive Analysis of E3 Ubiquitin Ligases Reveals Ring Finger Protein 223 as a Novel Oncogene Activated by KLF4 in Pancreatic Cancer. Frontiers in Cell and Developmental Biology. 9: 738709. PMID 34722520 DOI: 10.3389/fcell.2021.738709   
2021 Wang XD, Kim C, Zhang Y, Rindhe S, Cobb MH, Yu Y. Cholesterol Regulates the Tumor Adaptive Resistance to MAPK Pathway Inhibition. Journal of Proteome Research. PMID 34751028 DOI: 10.1021/acs.jproteome.1c00550   
2021 Tan T, Li J, Luo R, Wang R, Yin L, Liu M, Zeng Y, Zeng Z, Xie T. Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review. Molecules (Basel, Switzerland). 26. PMID 34641334 DOI: 10.3390/molecules26195792   
2021 Wei W, Feng Z, Liu Z, Li X, He H, Ran K, Shi Y, Zhu Y, Ye T, Gao C, Wang N, Yu L. Design, synthesis and biological evaluation of 7-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-2,3-dihydro-1H-inden-1-one derivatives as potent FAK inhibitors for the treatment of ovarian cancer. European Journal of Medicinal Chemistry. 113978. PMID 34810020 DOI: 10.1016/j.ejmech.2021.113978   
2021 Neagu AN, Whitham D, Buonanno E, Jenkins A, Alexa-Stratulat T, Tamba BI, Darie CC. Proteomics and its applications in breast cancer. American Journal of Cancer Research. 11: 4006-4049. PMID 34659875   
2021 Priyadarshini M, Maji S, Samal SK, Rath R, Li J, Das SK, Emdad L, Kundu CN, Fisher PB, Dash R. SARI inhibits growth and reduces survival of oral squamous cell carcinomas (OSCC) by inducing endoplasmic reticulum stress. Life Sciences. 287: 120141. PMID 34774620 DOI: 10.1016/j.lfs.2021.120141