Tiffany Freed - Related publications

2000-2001 Pharmacology Duke University, Durham, NC 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Alhadrami HA, Alkhatabi H, Abduljabbar FH, Abdelmohsen UR, Sayed AM. Anticancer Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Supported by Network Pharmacology and In Silico Analyses. Pharmaceutics. 13. PMID 34834261 DOI: 10.3390/pharmaceutics13111846   
2021 Kong B, Zhu Z, Li H, Hong Q, Wang C, Ma Y, Zheng W, Jiang F, Zhang Z, Ran T, Bian Y, Yang N, Lu T, Zhu J, Tang W, et al. Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy. European Journal of Medicinal Chemistry. 227: 113953. PMID 34731760 DOI: 10.1016/j.ejmech.2021.113953   
2021 Fino R, Lenhart D, Kalel VC, Softley CA, Napolitano V, Byrne R, Schliebs W, Dawidowski M, Erdmann R, Sattler M, Schneider G, Plettenburg O, Popowicz GM. Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents. Journal of Chemical Information and Modeling. PMID 34597510 DOI: 10.1021/acs.jcim.1c00472   
2021 Sarkar S, Swami S, Soni SK, Holien JK, Khan A, Korwar AM, Likhite AP, Joshi RA, Joshi RR, Sarkar D. Detection of a target protein (GroEl2) in Mycobacterium tuberculosis using a derivative of 1,2,4-triazolethiols. Molecular Diversity. PMID 34822095 DOI: 10.1007/s11030-021-10351-y   
2021 Rodrigues CHM, Pires DEV, Ascher DB. pdCSM-PPI: Using Graph-Based Signatures to Identify Protein-Protein Interaction Inhibitors. Journal of Chemical Information and Modeling. 61: 5438-5445. PMID 34719929 DOI: 10.1021/acs.jcim.1c01135   
2021 Luo R, Wang Z, Luo D, Qin Y, Zhao C, Yang D, Lu T, Zhou Z, Huang Z. Design, synthesis, and biological evaluation of novel triazoloquinazolinone derivatives as SHP2 protein inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 36: 2170-2182. PMID 34749564 DOI: 10.1080/14756366.2021.1986491   
2021 Zheng X, Zheng T, Liao Y, Luo L. Identification of Potential Inhibitors of MurD Enzyme of from a Marine Natural Product Library. Molecules (Basel, Switzerland). 26. PMID 34770835 DOI: 10.3390/molecules26216426   
2021 Soini L, Redhead M, Westwood M, Leysen S, Davis J, Ottmann C. Identification of molecular glues of the SLP76/14-3-3 protein-protein interaction. Rsc Medicinal Chemistry. 12: 1555-1564. PMID 34667951 DOI: 10.1039/d1md00172h   
2021 Norton D, Bonnette WG, Callahan JF, Carr MG, Griffiths-Jones CM, Heightman TD, Kerns JK, Nie H, Rich SJ, Richardson C, Rumsey W, Sanchez Y, Verdonk ML, Willems HMG, Wixted WE, et al. Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 34705450 DOI: 10.1021/acs.jmedchem.1c01351   
2021 Wullich SC, Wijma HJ, Janssen DB, Fetzner S. Stabilizing AqdC, a Pseudomonas Quinolone Signal-Cleaving Dioxygenase from Mycobacteria, by FRESCO-Based Protein Engineering. Chembiochem : a European Journal of Chemical Biology. 22: 733-742. PMID 33058333 DOI: 10.1002/cbic.202000641   
2021 Satari MH, Apriyanti E, Dharsono HDA, Nurdin D, Gartika M, Kurnia D. Effectiveness of Bioactive Compound as Antibacterial and Anti-Quorum Sensing Agent from : An In Silico Study. Molecules (Basel, Switzerland). 26. PMID 33922641 DOI: 10.3390/molecules26092465   
2021 Wu J, Hu B, Lu S, Duan R, Deng H, Li L, He L, Zhao Y, Wang J, Yu Z. Identification of raloxifene as a novel α-glucosidase inhibitor using a systematic drug repurposing approach in combination with cross molecular docking-based virtual screening and experimental verification. Carbohydrate Research. 511: 108478. PMID 34801925 DOI: 10.1016/j.carres.2021.108478   
2021 George A, Indhu M, Ashokraj S, Shanmugam G, Ganesan P, Kamini NR, Ayyadurai N. Genetically encoded dihydroxyphenylalanine coupled with tyrosinase for strain promoted labeling. Bioorganic & Medicinal Chemistry. 50: 116460. PMID 34757293 DOI: 10.1016/j.bmc.2021.116460   
2021 Reutershan MH, Machacek MR, Altman MD, Bogen S, Cai M, Cammarano C, Chen D, Christopher M, Cryan J, Daublain P, Fradera X, Geda P, Goldenblatt P, Hill AD, Kemper RA, et al. Discovery of : an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 34714078 DOI: 10.1021/acs.jmedchem.1c01524   
2021 Kamimura R, Uchida D, Kanno SI, Shiraishi R, Hyodo T, Sawatani Y, Shimura M, Hasegawa T, Tsubura-Okubo M, Yaguchi E, Komiyama Y, Fukumoto C, Izumi S, Fujita A, Wakui T, et al. Identification of Binding Proteins for TSC22D1 Family Proteins Using Mass Spectrometry. International Journal of Molecular Sciences. 22. PMID 34681573 DOI: 10.3390/ijms222010913   
2021 Ghosh DK, Ranjan A. HYPK coordinates degradation of polyneddylated proteins by autophagy. Autophagy. 1-22. PMID 34836490 DOI: 10.1080/15548627.2021.1997053   
2021 Wang W, Zhang Y, Zhao H, Zhuang X, Wang H, He K, Xu W, Kang Y, Chen S, Zeng S, Qian L. Real-time imaging of cell-surface proteins with antibody-based fluorogenic probes. Chemical Science. 12: 13477-13482. PMID 34777767 DOI: 10.1039/d1sc03065e   
2021 Nallappan D, Fauzi AN, Krishna BS, Kumar BP, Reddy AVK, Syed T, Reddy CS, Yaacob NS, Rao PV. Green Biosynthesis, Antioxidant, Antibacterial, and Anticancer Activities of Silver Nanoparticles of Leaf Extract. Biomed Research International. 2021: 5125681. PMID 34631882 DOI: 10.1155/2021/5125681   
2021 Javed T, Raja SA, Rehman KU, Khalid S, Khalid N, Riaz S. In silico bimolecular characterization of anticancer phytochemicals from Fagonia indica. Pakistan Journal of Pharmaceutical Sciences. 34: 883-889. PMID 34602410   
2021 Watroly MN, Sekar M, Fuloria S, Gan SH, Jeyabalan S, Wu YS, Subramaniyan V, Sathasivam KV, Ravi S, Mat Rani NNI, Lum PT, Vaijanathappa J, Meenakshi DU, Mani S, Fuloria NK. Chemistry, Biosynthesis, Physicochemical and Biological Properties of Rubiadin: A Promising Natural Anthraquinone for New Drug Discovery and Development. Drug Design, Development and Therapy. 15: 4527-4549. PMID 34764636 DOI: 10.2147/DDDT.S338548   
2021 Wu WJ, Xia CL, Ou SJ, Yang Y, Ma YF, Hou YL, Yang QP, Zhang J, Li JW, Qi Y, Xu CP. Novel Elongator Protein 2 Inhibitors Mitigating Tumor Necrosis Factor- Induced Osteogenic Differentiation Inhibition. Biomed Research International. 2021: 3664564. PMID 34853789 DOI: 10.1155/2021/3664564   
2021 Hung SW, Liang B, Gao Y, Zhang R, Tan Z, Zhang T, Chung PWJ, Chan TH, Wang CC. An , and Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis. Frontiers in Pharmacology. 12: 714790. PMID 34721014 DOI: 10.3389/fphar.2021.714790   
2021 Dai M, Yuan D, Lei Y, Li J, Ren Y, Zhang Y, Cang H, Gao W, Tang Y. Expression, purification and structural characterization of resveratrol synthase from Polygonum cuspidatum. Protein Expression and Purification. 106024. PMID 34808343 DOI: 10.1016/j.pep.2021.106024   
2021 Karale A, Lokhande KB, Shende N, Swamy KV, Dhere R, Nawani N, Mallya A. Transferrin binding protein-B from C as a novel carrier protein in glycoconjugate preparation: an approach. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 34726113 DOI: 10.1080/07391102.2021.1994878   
2021 Ryan A, Hammond GRV, Deiters A. Optical Control of Phosphoinositide Binding: Rapid Activation of Subcellular Protein Translocation and Cell Signaling. Acs Synthetic Biology. 10: 2886-2895. PMID 34748306 DOI: 10.1021/acssynbio.1c00328   
2021 Gomes LR, Durans AM, Napoleão-Pêgo P, Waterman JA, Freitas MS, De Sá NBR, Pereira LV, Furtado JS, Aquino RG, Machado MCR, Fintelman-Rodrigues N, Souza TML, Morel CM, Provance DW, De-Simone SG. Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2. Vaccines. 9. PMID 34579223 DOI: 10.3390/vaccines9090986   
2021 Panyain N, Godinat A, Thawani AR, Lachiondo-Ortega S, Mason K, Elkhalifa S, Smith LM, Harrigan JA, Tate EW. Activity-based protein profiling reveals deubiquitinase and aldehyde dehydrogenase targets of a cyanopyrrolidine probe. Rsc Medicinal Chemistry. 12: 1935-1943. PMID 34820624 DOI: 10.1039/d1md00218j   
2021 Shafique QUA, Rehman HM, Zaheer T, Tahir RA, Bhinder MA, Gul R, Saleem M. A Computational Approach to Modeling an Antagonistic Angiogenic VEGFR1-IL2 Fusion Protein for Cancer Therapy. Bioinformatics and Biology Insights. 15: 11779322211043297. PMID 34566410 DOI: 10.1177/11779322211043297   
2021 Pathanraj D, Choowongkomon K, Roytrakul S, Yokthongwattana C. Structural Distinctive 26SK, a Ribosome-Inactivating Protein from Jatropha curcas and Its Biological Activities. Applied Biochemistry and Biotechnology. PMID 34669111 DOI: 10.1007/s12010-021-03714-6   
2021 Ahmed H, Ajat M, Mahmood RI, Mansor R, Razak ISA, Al-Obaidi JR, Razali N, Jaji AZ, Danmaigoro A, Bakar MZA. LC-MS/MS Proteomic Study of MCF-7 Cell Treated with Dox and Dox-Loaded Calcium Carbonate Nanoparticles Revealed Changes in Proteins Related to Glycolysis, Actin Signalling, and Energy Metabolism. Biology. 10. PMID 34571787 DOI: 10.3390/biology10090909   
2021 Sen S, Sultana N, Shaffer SA, Thompson PR. Proximity-Dependent Labeling of Cysteines. Journal of the American Chemical Society. PMID 34762412 DOI: 10.1021/jacs.1c07069   
2021 Grigglestone CE, Yeung KS. Degradation of Protein Kinases: Ternary Complex, Cooperativity, and Selectivity. Acs Medicinal Chemistry Letters. 12: 1629-1632. PMID 34795847 DOI: 10.1021/acsmedchemlett.1c00543   
2021 Anwaar MU, Adnan F, Abro A, Khan RA, Rehman AU, Osama M, Rainville C, Kumar S, Sterner D, Javed S, Jamal SB, Baig A, Shabbir MR, Ahsan W, Butt TR, et al. Combined deep learning and molecular docking simulations approach identifies potentially effective FDA approved drugs for repurposing against SARS-CoV-2. Computers in Biology and Medicine. 105049. PMID 34823857 DOI: 10.1016/j.compbiomed.2021.105049   
2021 Rehman A, Wang X, Ahmad S, Shahid F, Aslam S, Ashfaq UA, Alrumaihi F, Qasim M, Hashem A, Al-Hazzani AA, Abd Allah EF. In Silico Core Proteomics and Molecular Docking Approaches for the Identification of Novel Inhibitors against . International Journal of Environmental Research and Public Health. 18. PMID 34769873 DOI: 10.3390/ijerph182111355   
2021 Nagarajan M, Maadurshni GB, Manivannan J. Systems toxicology approach explores target-pathway relationship and adverse health impacts of ubiquitous environmental pollutant bisphenol A. Journal of Toxicology and Environmental Health. Part A. 1-13. PMID 34706627 DOI: 10.1080/15287394.2021.1994492   
2021 Pei J, Pan X, Wang A, Shuai W, Bu F, Tang P, Zhang S, Zhang Y, Wang G, Ouyang L. Developing potent LC3-targeting AUTAC tools for protein degradation with selective autophagy. Chemical Communications (Cambridge, England). PMID 34816823 DOI: 10.1039/d1cc04661f   
2021 Kaur H, Singh V, Kalia M, Mohan B, Taneja N. Identification and functional annotation of hypothetical proteins of uropathogenic strain CFT073 towards designing antimicrobial drug targets. Journal of Biomolecular Structure & Dynamics. 1-12. PMID 34751095 DOI: 10.1080/07391102.2021.2000499   
2021 Moiani D, Link TM, Brosey CA, Katsonis P, Lichtarge O, Kim Y, Joachimiak A, Ma Z, Kim IK, Ahmed Z, Jones DE, Tsutakawa SE, Tainer JA. An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2. Methods in Enzymology. 661: 407-431. PMID 34776222 DOI: 10.1016/bs.mie.2021.09.003   
2021 Khan RA, Hossain R, Siyadatpanah A, Al-Khafaji K, Khalipha ABR, Dey D, Asha UH, Biswas P, Saikat ASM, Chenari HA, Wilairatana P, Islam MT. Diterpenes/Diterpenoids and Their Derivatives as Potential Bioactive Leads against Dengue Virus: A Computational and Network Pharmacology Study. Molecules (Basel, Switzerland). 26. PMID 34833913 DOI: 10.3390/molecules26226821   
2021 Avolio E, Carrabba M, Milligan R, Kavanagh Williamson M, Beltrami A, Gupta K, Elvers KT, Gamez M, Foster R, Gillespie K, Hamilton F, Arnold D, Berger I, Davidson A, Hill DJ, et al. The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease. Clinical Science (London, England : 1979). PMID 34807265 DOI: 10.1042/CS20210735   
2021 Rose M, Cardon T, Aboulouard S, Hajjaji N, Kobeissy F, Duhamel M, Fournier I, Salzet M. Surfaceome Proteomic of Glioblastoma Revealed Potential Targets for Immunotherapy. Frontiers in Immunology. 12: 746168. PMID 34646273 DOI: 10.3389/fimmu.2021.746168   
2021 Savitt AG, Manimala S, White T, Fandaros M, Yin W, Duan H, Xu X, Geisbrecht BV, Rubenstein DA, Kaplan AP, Peerschke EI, Ghebrehiwet B. SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems. Frontiers in Immunology. 12: 767347. PMID 34804054 DOI: 10.3389/fimmu.2021.767347   
2021 Chakravarti R. Immune regulations by 14-3-3: A misty terrain. Immunobiology. 226: 152145. PMID 34628289 DOI: 10.1016/j.imbio.2021.152145   
2021 Mamidala E, Davella R, Praveen Kumar M, Swamy S, Abhiav M, Ali Kaimkhani Z, Al-Ghanim KA, Mahboob S. Prediction of Mozenavir as a potential drug for SARS-CoV-2 infection via Binding Multiple Drug Targets. Saudi Journal of Biological Sciences. PMID 34690521 DOI: 10.1016/j.sjbs.2021.10.023   
2021 Nussinov R, Zhang M, Maloney R, Tsai CJ, Yavuz BR, Tuncbag N, Jang H. Mechanism of activation and the rewired network: New drug design concepts. Medicinal Research Reviews. PMID 34693559 DOI: 10.1002/med.21863   
2021 Ghosh N, Saha I, Sharma N. Interactome of human and SARS-CoV-2 proteins to identify human hub proteins associated with comorbidities. Computers in Biology and Medicine. 138: 104889. PMID 34655901 DOI: 10.1016/j.compbiomed.2021.104889   
2021 Wu WH, Bai X, Shao Y, Yang C, Wei J, Wei W, Zhang WB. Higher Order Protein Catenation Leads to an Artificial Antibody with Enhanced Affinity and In Vivo Stability. Journal of the American Chemical Society. PMID 34664942 DOI: 10.1021/jacs.1c06169   
2021 Yoon NG, Lee H, Kim SY, Hu S, Kim D, Yang S, Hong KB, Lee JH, Kang S, Kim BG, Myung K, Lee C, Kang BH. Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site. Journal of the American Chemical Society. PMID 34758612 DOI: 10.1021/jacs.1c07099   
2021 Pujari I, Sengupta R, Babu VS. Docking and ADMET studies for investigating the anticancer potency of Moscatilin on APC10/DOC1 and PKM2 against five clinical drugs. Journal, Genetic Engineering & Biotechnology. 19: 161. PMID 34665359 DOI: 10.1186/s43141-021-00256-6   
2021 Balmeh N, Mahmoudi S, Fard NA. Manipulated bio antimicrobial peptides from probiotic bacteria as proposed drugs for COVID-19 disease. Informatics in Medicine Unlocked. 23: 100515. PMID 33521241 DOI: 10.1016/j.imu.2021.100515