Edmond H. Fischer - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
structure and regulation of enzymes, control of cellular processes by hormones and growth factors, role of protein tyrosine phosphatases in signal transduction, cell cycle, and transformation
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1992/fischer-bio.html

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Fischer EH. How I became a biochemist: For Bill Whelan's Festschrift. Molecular Aspects of Medicine. PMID 26297191 DOI: 10.1016/j.mam.2015.07.002  1
2013 Fischer EH. Cellular regulation by protein phosphorylation Biochemical and Biophysical Research Communications. 430: 865-867. PMID 23058924 DOI: 10.1016/j.bbrc.2012.10.024  1
2010 Fischer EH. Phosphorylase and the origin of reversible protein phosphorylation Biological Chemistry. 391: 131-137. PMID 20030590 DOI: 10.1515/BC.2010.011  1
2009 Fischer EH, Piguet A. Macromolecules and Enzymes: The Geneva Heritage from Kurt H. Meyer and Edmond H. Fischer. Chimia. 63: 835-838. PMID 28372606 DOI: 10.2533/chimia.2009.835  0.72
2002 Fischer EH. Basic biological research at the dawn of a new century Molecular Neurobiology. 26: iii-vii. PMID 12428751 DOI: 10.1385/MN:26:2-3:iii  1
2001 Arrow KJ, Axelrod J, Benacerraf B, Berg P, Bishop JM, Bloembergen N, Brown HC, Cibelli J, Cohen S, Cooper LN, Corey EJ, Cronin JW, Curl R, Dulbecco R, Fischer EH, et al. Nobel laureates' letter to President Bush. The Washington Post. A02. PMID 12462241  1
2000 Lurie DI, Solca F, Fischer EH, Rubel EW. Tyrosine phosphatase SHP-1 immunoreactivity increases in a subset of astrocytes following deafferentation of the chicken auditory brainstem. The Journal of Comparative Neurology. 421: 199-214. PMID 10813782 DOI: 10.1002/(SICI)1096-9861(20000529)421:2<199::AID-CNE6>3.0.CO;2-G  1
1999 Fischer EH. Cell signaling by protein tyrosine phosphorylation. Advances in Enzyme Regulation. 39: 359-69. PMID 10470384 DOI: 10.1016/S0065-2571(98)00014-4  1
1999 Maret W, Jacob C, Vallee BL, Fischer EH. Inhibitory sites in enzymes: Zinc removal and reactivation by thionein Proceedings of the National Academy of Sciences of the United States of America. 96: 1936-1940. PMID 10051573 DOI: 10.1073/pnas.96.5.1936  1
1998 Fischer EH, Davie EW. Recent excitement regarding metallothionein. Proceedings of the National Academy of Sciences of the United States of America. 95: 3333-4. PMID 9520361 DOI: 10.1073/pnas.95.7.3333  1
1997 Fischer EH. Cellular regulation by protein phosphorylation: a historical overview. Biofactors (Oxford, England). 6: 367-74. PMID 9288407  1
1997 Reszka AA, Bulinski JC, Krebs EG, Fischer EH. Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions. Molecular Biology of the Cell. 8: 1219-32. PMID 9243503  1
1997 Sakakura C, Sweeney EA, Shirahama T, Ruan F, Solca F, Kohno M, Hakomori SI, Fischer EH, Igarashi Y. Inhibition of MAP kinase by sphingosine and its methylated derivative, N,N-dimethylsphingosine: A correlation with induction of apoptosis in solid tumor cells International Journal of Oncology. 11: 31-39.  1
1996 Eldar-Finkelman H, Argast GM, Foord O, Fischer EH, Krebs EG. Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 10228-33. PMID 8816781 DOI: 10.1073/pnas.93.19.10228  1
1996 Borges LG, Seifert RA, Grant FJ, Hart CE, Disteche CM, Edelhoff S, Solca FF, Lieberman MA, Lindner V, Fischer EH, Lok S, Bowen-Pope DF. Cloning and characterization of rat density-enhanced phosphatase-1, a protein tyrosine phosphatase expressed by vascular cells. Circulation Research. 79: 570-80. PMID 8781490  1
1996 Zhao Z, Tan Z, Diltz CD, You M, Fischer EH. Activation of mitogen-activated protein (MAP) kinase pathway by pervanadate, a potent inhibitor of tyrosine phosphatases. The Journal of Biological Chemistry. 271: 22251-5. PMID 8703041 DOI: 10.1074/jbc.271.36.22251  1
1996 Law CL, Sidorenko SP, Chandran KA, Zhao Z, Shen SH, Fischer EH, Clark EA. CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation. The Journal of Experimental Medicine. 183: 547-60. PMID 8627166 DOI: 10.1084/jem.183.2.547  1
1996 Su L, Zhao Z, Bouchard P, Banville D, Fischer EH, Krebs EG, Shen SH. Positive effect of overexpressed protein-tyrosine phosphatase PTP1C on mitogen-activated signaling in 293 cells. The Journal of Biological Chemistry. 271: 10385-90. PMID 8626611 DOI: 10.1074/jbc.271.17.10385  1
1996 Adachi M, Fischer EH, Ihle J, Imai K, Jirik F, Neel B, Pawson T, Shen S, Thomas M, Ullrich A, Zhao Z. Mammalian SH2-containing protein tyrosine phosphatases. Cell. 85: 15. PMID 8620532  1
1995 Zhao Z, Tan Z, Wright JH, Diltz CD, Shen SH, Krebs EG, Fischer EH. Altered expression of protein-tyrosine phosphatase 2C in 293 cells affects protein tyrosine phosphorylation and mitogen-activated protein kinase activation. The Journal of Biological Chemistry. 270: 11765-9. PMID 7744825 DOI: 10.1074/jbc.270.20.11765  1
1995 Lorenzen JA, Dadabay CY, Fischer EH. COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus. The Journal of Cell Biology. 131: 631-43. PMID 7593185 DOI: 10.1083/jcb.131.3.631  1
1995 Reszka AA, Seger R, Diltz CD, Krebs EG, Fischer EH. Association of mitogen-activated protein kinase with the microtubule cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 92: 8881-5. PMID 7568036 DOI: 10.1073/pnas.92.19.8881  1
1994 Zhao Z, Shen SH, Fischer EH. Phorbol ester-induced expression, phosphorylation, and translocation of protein-tyrosine-phosphatase 1C in HL-60 cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 5007-11. PMID 8197173 DOI: 10.1073/pnas.91.11.5007  1
1994 Peraldi P, Zhao Z, Filloux C, Fischer EH, Van Obberghen E. Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 91: 5002-6. PMID 8197172 DOI: 10.1073/pnas.91.11.5002  1
1994 Daum G, Regenass S, Sap J, Schlessinger J, Fischer EH. Multiple forms of the human tyrosine phosphatase RPTP alpha. Isozymes and differences in glycosylation. The Journal of Biological Chemistry. 269: 10524-8. PMID 8144638  1
1994 Zhao Z, Larocque R, Ho WT, Fischer EH, Shen SH. Purification and characterization of PTP2C, a widely distributed protein tyrosine phosphatase containing two SH2 domains. The Journal of Biological Chemistry. 269: 8780-5. PMID 8132610  1
1994 Solca FF, Lurie DI, Diltz CD, Johnson RS, Kumar S, Rubel EW, Fischer EH. Identification and purification of a chicken brain neuroglia-associated protein. The Journal of Biological Chemistry. 269: 27559-65. PMID 7961672  1
1994 Seger R, Seger D, Reszka AA, Munar ES, Eldar-Finkelman H, Dobrowolska G, Jensen AM, Campbell JS, Fischer EH, Krebs EG. Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. The Journal of Biological Chemistry. 269: 25699-709. PMID 7929275  1
1994 Bouchard P, Zhao Z, Banville D, Dumas F, Fischer EH, Shen SH. Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C. The Journal of Biological Chemistry. 269: 19585-9. PMID 7518460  1
1994 Kuhné MR, Zhao Z, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE. Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C. The Journal of Biological Chemistry. 269: 15833-7. PMID 7515062  1
1993 Zhao Z, Bouchard P, Diltz CD, Shen SH, Fischer EH. Purification and characterization of a protein tyrosine phosphatase containing SH2 domains. The Journal of Biological Chemistry. 268: 2816-20. PMID 8428956  0.44
1993 Johnson CV, Cool DE, Glaccum MB, Green N, Fischer EH, Bruskin A, Hill DE, Lawrence JB. Isolation and mapping of human T-cell protein tyrosine phosphatase sequences: localization of genes and pseudogenes discriminated using fluorescence hybridization with genomic versus cDNA probes. Genomics. 16: 619-29. PMID 8325634 DOI: 10.1006/geno.1993.1239  1
1993 Daum G, Solca F, Diltz CD, Zhao Z, Cool DE, Fischer EH. A general peptide substrate for protein tyrosine phosphatases. Analytical Biochemistry. 211: 50-4. PMID 8323038  0.44
1993 Cool DE, Fischer EH. Protein tyrosine phosphatases in cell transformation. Seminars in Cell Biology. 4: 443-53. PMID 8305683  0.44
1993 Lammers R, Bossenmaier B, Cool DE, Tonks NK, Schlessinger J, Fischer EH, Ullrich A. Differential activities of protein tyrosine phosphatases in intact cells. The Journal of Biological Chemistry. 268: 22456-62. PMID 7693671  0.44
1993 Zhao Z, Shen SH, Fischer EH. Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domains. Proceedings of the National Academy of Sciences of the United States of America. 90: 4251-5. PMID 7683430  0.36
1993 Zander NF, Cool DE, Diltz CD, Rohrschneider LR, Krebs EG, Fischer EH. Suppression of v-fms-induced transformation by overexpression of a truncated T-cell protein tyrosine phosphatase. Oncogene. 8: 1175-82. PMID 7683129  1
1993 Ahmad S, Banville D, Zhao Z, Fischer EH, Shen SH. A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains. Proceedings of the National Academy of Sciences of the United States of America. 90: 2197-201. PMID 7681589  0.36
1992 Cool DE, Andreassen PR, Tonks NK, Krebs EG, Fischer EH, Margolis RL. Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 89: 5422-6. PMID 1608952 DOI: 10.1073/pnas.89.12.5422  1
1992 Rotin D, Margolis B, Mohammadi M, Daly RJ, Daum G, Li N, Fischer EH, Burgess WH, Ullrich A, Schlessinger J. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma. The Embo Journal. 11: 559-67. PMID 1537335  1
1992 Fischer EH, Charbonneau H, Cool DE, Tonks NK. Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposium. 164: 132-40; discussion 1. PMID 1395930  1
1992 Zhao Z, Zander NF, Malencik DA, Anderson SR, Fischer EH. Continuous spectrophotometric assay of protein tyrosine phosphatase using phosphotyrosine. Analytical Biochemistry. 202: 361-6. PMID 1381565  0.36
1991 Tonks NK, Diltz CD, Fischer EH. Purification and assay of CD45: an integral membrane protein-tyrosine phosphatase. Methods in Enzymology. 201: 442-51. PMID 1719347  0.44
1991 Tonks NK, Diltz CD, Fischer EH. Purification of protein-tyrosine phosphatases from human placenta. Methods in Enzymology. 201: 427-42. PMID 1719346  0.44
1991 Fischer EH, Charbonneau H, Tonks NK. Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science (New York, N.Y.). 253: 401-6. PMID 1650499  1
1991 Zander NF, Lorenzen JA, Cool DE, Tonks NK, Daum G, Krebs EG, Fischer EH. Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry. 30: 6964-70. PMID 1648966  1
1991 Daum G, Zander NF, Morse B, Hurwitz D, Schlessinger J, Fischer EH. Characterization of a human recombinant receptor-linked protein tyrosine phosphatase. The Journal of Biological Chemistry. 266: 12211-5. PMID 1648088  0.32
1990 Cool DE, Tonks NK, Charbonneau H, Fischer EH, Krebs EG. Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 7280-4. PMID 2169624  1
1990 Haystead TA, Weiel JE, Litchfield DW, Tsukitani Y, Fischer EH, Krebs EG. Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal. The Journal of Biological Chemistry. 265: 16571-80. PMID 2168895  1
1990 Cicirelli MF, Tonks NK, Diltz CD, Weiel JE, Fischer EH, Krebs EG. Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 5514-8. PMID 2164686 DOI: 10.1073/pnas.87.14.5514  1
1990 Tonks NK, Diltz CD, Fischer EH. CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity. The Journal of Biological Chemistry. 265: 10674-80. PMID 2162357  0.44
1990 Tonks NK, Cicirelli MF, Diltz CD, Krebs EG, Fischer EH. Effect of microinjection of a low-Mr human placenta protein tyrosine phosphatase on induction of meiotic cell division in Xenopus oocytes. Molecular and Cellular Biology. 10: 458-63. PMID 2153916  1
1990 Fischer EH, Tonks NK, Charbonneau H, Cicirelli MF, Cool DE, Diltz CD, Krebs EG, Walsh KA. Protein tyrosine phosphatases: a novel family of enzymes involved in transmembrane signalling. Advances in Second Messenger and Phosphoprotein Research. 24: 273-9. PMID 1698407  1
1989 Lerea KM, Tonks NK, Krebs EG, Fischer EH, Glomset JA. Vanadate and molybdate increase tyrosine phosphorylation in a 50-kilodalton protein and stimulate secretion in electropermeabilized platelets. Biochemistry. 28: 9286-92. PMID 2558716  1
1989 Cool DE, Tonks NK, Charbonneau H, Walsh KA, Fischer EH, Krebs EG. cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family. Proceedings of the National Academy of Sciences of the United States of America. 86: 5257-61. PMID 2546150  1
1989 Charbonneau H, Tonks NK, Kumar S, Diltz CD, Harrylock M, Cool DE, Krebs EG, Fischer EH, Walsh KA. Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins. Proceedings of the National Academy of Sciences of the United States of America. 86: 5252-6. PMID 2546149  1
1989 Krebs EG, Fischer EH. The phosphorylase b to a converting enzyme of rabbit skeletal muscle. 1956. Biochimica Et Biophysica Acta. 1000: 302-9. PMID 2505847  1
1989 Fischer EH, Krebs EG. Commentary on 'The Phosphorylase b to a Converting Enzyme of Rabbit Skeletal Muscle". Biochimica Et Biophysica Acta. 1000: 297-301. PMID 2505846  1
1988 Ledbetter JA, Tonks NK, Fischer EH, Clark EA. CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 8628-32. PMID 2973067  1
1988 Tonks NK, Charbonneau H, Diltz CD, Fischer EH, Walsh KA. Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry. 27: 8695-701. PMID 2853967  1
1988 Charbonneau H, Tonks NK, Walsh KA, Fischer EH. The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 85: 7182-6. PMID 2845400  1
1988 Chan CP, McNall SJ, Krebs EG, Fischer EH. Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 6257-61. PMID 2842761  1
1988 Tonks NK, Diltz CD, Fischer EH. Characterization of the major protein-tyrosine-phosphatases of human placenta. The Journal of Biological Chemistry. 263: 6731-7. PMID 2834387  0.44
1988 Tonks NK, Diltz CD, Fischer EH. Purification of the major protein-tyrosine-phosphatases of human placenta. The Journal of Biological Chemistry. 263: 6722-30. PMID 2834386  0.44
1987 Alvord EC, Jahnke U, Fischer EH. The causes of the syndromes of Landry (1859) and of Guillain, Barré and Strohl (1916). Revue Neurologique. 143: 571-9. PMID 2445014  1
1987 Alvord EC, Jahnke U, Fischer EH, Kies MW, Driscoll BF, Compston DA. The multiple causes of multiple sclerosis: the importance of age of infections in childhood. Journal of Child Neurology. 2: 313-21. PMID 2443550 DOI: 10.1177/088307388700200418  1
1986 Malencik DA, Scott JD, Fischer EH, Krebs EG, Anderson SR. Association of calmodulin with peptide analogues of the inhibitory region of the heat-stable protein inhibitor of adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry. 25: 3502-08. PMID 3755057  1
1986 Scott JD, Glaccum MB, Fischer EH, Krebs EG. Primary-structure requirements for inhibition by the heat-stable inhibitor of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 1613-6. PMID 3456605  1
1985 Scott JD, Fischer EH, Takio K, Demaille JG, Krebs EG. Amino acid sequence of the heat-stable inhibitor of the cAMP-dependent protein kinase from rabbit skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 82: 5732-6. PMID 3898070 DOI: 10.1073/pnas.82.17.5732  1
1985 Scott JD, Fischer EH, Demaille JG, Krebs EG. Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 82: 4379-83. PMID 2989819  1
1985 Jahnke U, Fischer EH, Alvord EC. Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis. Science (New York, N.Y.). 229: 282-4. PMID 2409602  1
1984 Reimann EM, Titani K, Ericsson LH, Wade RD, Fischer EH, Walsh KA. Homology of the gamma subunit of phosphorylase b kinase with cAMP-dependent protein kinase. Biochemistry. 23: 4185-92. PMID 6541504  0.44
1983 Job D, Rauch CT, Fischer EH, Margolis RL. Regulation of microtubule cold stability by calmodulin-dependent and -independent phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 80: 3894-8. PMID 6575383  0.36
1983 Shoji S, Ericsson LH, Walsh KA, Fischer EH, Titani K. Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry. 22: 3702-9. PMID 6311252  1
1983 Ballou LM, Brautigan DL, Fischer EH. Subunit structure and activation of inactive phosphorylase phosphatase. Biochemistry. 22: 3393-9. PMID 6311247  1
1973 Cohen P, Saari JC, Fischer EH. Comparative study of dogfish and rabbit muscle phosphorylases. Biochemistry. 12: 5233-41. PMID 4796798  0.96
1971 Cohen P, Duewer T, Fischer EH. Phosphorylase from dogfish skeletal muscle. Purification and a comparison of its physical properties to those of rabbit muscle phosphorylase. Biochemistry. 10: 2683-94. PMID 5558692  0.96
1950 FISCHER EH, MEYER KH, NOELTING G, PIGUET A. The purification and crystallization of malt beta-amylase. Archives of Biochemistry. 27: 235-7. PMID 15419794  1
1948 MEYER KH, FISCHER EH. Purification and crystallization of human pancreatic amylase. Archives of Biochemistry. 18: 203-5. PMID 18871231  1
1948 MEYER KH, FISCHER EH. [Not Available]. Helvetica Chimica Acta. 31: 2158-64. PMID 18100047  1
1947 MEYER KH, FISCHER EH, BERNFELD P. [Not Available]. Experientia. 3: 106. PMID 20340306  1
1947 MEYER KH, FISCHER EH, BERNFELD P. [Not Available]. Helvetica Chimica Acta. 30: 64-78. PMID 20294134  1
1947 MEYER KH, FISCHER EH, BERNFELD P. Physical and chemical properties of crystalline alpha-amylase of hog pancreas. Archives of Biochemistry. 14: 149-52. PMID 20251343  1
1946 MEYER KH, FISCHER EH, BERNFELD P. [Not Available]. Experientia. 2: 362. PMID 20291762  1
Show low-probability matches.