Amarendar Maddirala - Publications

Affiliations: 
2016- Biochemistry and Molecular Biophysics Washington University, Saint Louis, St. Louis, MO 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Maddirala AR, Tamadonfar K, Pinkner JS, Sanick D, Hultgren SJ, Janetka JW. Discovery of Orally Bioavailable FmlH Lectin Antagonists as Treatment for Urinary Tract Infections. Journal of Medicinal Chemistry. PMID 38308631 DOI: 10.1021/acs.jmedchem.3c02128  0.626
2020 Damalanka VC, Maddirala AR, Janetka JW. Novel approaches to glycomimetic design: Development of small molecular weight lectin antagonists. Expert Opinion On Drug Discovery. PMID 33337918 DOI: 10.1080/17460441.2021.1857721  0.675
2018 Maddirala A, Klein RD, Pinkner J, Kalas V, Hultgren SJ, Janetka JW. Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through iterative rational drug design. Journal of Medicinal Chemistry. PMID 30540910 DOI: 10.1021/Acs.Jmedchem.8B01561  0.613
2018 Esmati N, Maddirala AR, Hussein N, Amawi H, Tiwari AK, Andreana PR. Efficient syntheses and anti-cancer activity of xenortides A-D including ent/epi-stereoisomers. Organic & Biomolecular Chemistry. PMID 29999086 DOI: 10.1039/C8Ob00452H  0.604
2018 Maddirala AR, Andreana PR. Methyl isocyanide as a convertible functional group for the synthesis of spirocyclic oxindole γ-lactams via post-Ugi-4CR/transamidation/cyclization in a one-pot, three-step sequence. Beilstein Journal of Organic Chemistry. 14: 875-883. PMID 29765468 DOI: 10.3762/Bjoc.14.74  0.638
2018 Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman C, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley P, Tseng CC, Greig IR, Sakanari J, Wildman SA, et al. Small molecule inhibitors of metabolic enzymes repurposed as a new class of anthelmintics. Acs Infectious Diseases. PMID 29718656 DOI: 10.1021/Acsinfecdis.8B00090  0.625
2018 Kalas V, Hibbing ME, Maddirala AR, Chugani R, Pinkner JS, Mydock-McGrane LK, Conover MS, Janetka JW, Hultgren SJ. Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507247 DOI: 10.1073/Pnas.1720140115  0.601
2017 Rutaganira FU, Barks J, Dhason MS, Wang Q, Lopez MS, Long S, Radke JB, Jones NG, Maddirala AR, Janetka JW, El Bakkouri M, Hui R, Shokat KM, Sibley LD. Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii. Journal of Medicinal Chemistry. PMID 28933846 DOI: 10.1021/Acs.Jmedchem.7B01192  0.627
2016 Maddirala AR, Andreana PR. Synthesis of 3-Substituted 2-Indolinones by a Multicomponent Coupling Isocyanide-Dependent Microwave-Assisted Intramolecular Transamidation Process European Journal of Organic Chemistry. 2016: 196-209. DOI: 10.1002/Ejoc.201501273  0.638
2014 Bourgault JP, Maddirala AR, Andreana PR. A one-pot multicomponent coupling/cyclization for natural product herbicide (±)-thaxtomin A. Organic & Biomolecular Chemistry. 12: 8125-7. PMID 25058709 DOI: 10.1039/C4Ob01148A  0.602
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