Mark A. L. Atkinson, Phd - Publications

Affiliations: 
 

309 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 F De Jesus D, Zhang Z, Brown NK, Li X, Xiao L, Hu J, Gaffrey MJ, Fogarty G, Kahraman S, Wei J, Basile G, Rana TM, Mathews C, Powers AC, Parent AV, ... Atkinson MA, et al. Redox regulation of mA methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes. Nature Cell Biology. PMID 38409327 DOI: 10.1038/s41556-024-01368-0  0.313
2023 Beran D, Koch M, Ajmal S, de Beaufort C, Ramaiya K, Zafra-Tanaka JH, Atkinson M. The Lancet Diabetes & Endocrinology Commission on type 1 diabetes: looking back to move forward. The Lancet. Diabetes & Endocrinology. PMID 37972630 DOI: 10.1016/S2213-8587(23)00323-6  0.372
2023 Redondo MJ, Harrall KK, Glueck DH, Tosur M, Uysal S, Muir A, Atkinson EG, Shapiro MR, Yu L, Winter WE, Weedon M, Brusko TM, Oram R, Vehik K, Hagopian W, Atkinson MA, et al. Diabetes Study of Children of Diverse Ethnicity and Race: Study design. Diabetes/Metabolism Research and Reviews. e3744. PMID 37888801 DOI: 10.1002/dmrr.3744  0.339
2023 Atkinson MA, Mirmira RG. The pathogenic "symphony" in type 1 diabetes: A disorder of the immune system, β cells, and exocrine pancreas. Cell Metabolism. PMID 37478842 DOI: 10.1016/j.cmet.2023.06.018  0.345
2023 Perry DJ, Shapiro MR, Chamberlain SW, Kusmartseva I, Chamala S, Balzano-Nogueira L, Yang M, Brant JO, Brusko M, Williams MD, McGrail KM, McNichols J, Peters LD, Posgai AL, Kaddis JS, ... ... Atkinson MA, et al. A genomic data archive from the Network for Pancreatic Organ donors with Diabetes. Scientific Data. 10: 323. PMID 37237059 DOI: 10.1038/s41597-023-02244-6  0.362
2023 Morales JF, Muse R, Podichetty J, Burton J, David S, Lang P, Schmidt S, Romero K, O'Doherty I, Martin F, Campbell-Thompson M, Haller MJ, Atkinson MA, Kim S. Disease Progression Joint Model Predicts Time to Type 1 Diabetes Onset: Optimizing Future Type 1 Diabetes Prevention Studies. Cpt: Pharmacometrics & Systems Pharmacology. PMID 37186151 DOI: 10.1002/psp4.12973  0.383
2023 Wilson DM, Pietropaolo SL, Acevedo-Calado M, Huang S, Anyaiwe D, Scheinker D, Steck AK, Vasudevan MM, McKay SV, Sherr JL, Herold KC, Dunne JL, Greenbaum CJ, Lord SM, Haller MJ, ... ... Atkinson MA, et al. CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study. Diabetes Care. PMID 36730530 DOI: 10.2337/dc22-1297  0.328
2022 Redondo MJ, Richardson SJ, Perry D, Minard CG, Carr ALJ, Brusko T, Kusmartseva I, Pugliese A, Atkinson MA. Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants. Diabetologia. PMID 36282337 DOI: 10.1007/s00125-022-05818-y  0.389
2022 Kulkarni S, Posgai AL, Kusmartseva I, Wasserfall CH, Atkinson MA, Butler AE. Exocrine and Endocrine Inflammation Increases Cellular Replication in the Pancreatic Duct Compartment in Type 1 Diabetes. Journal of the Endocrine Society. 6: bvac136. PMID 36249412 DOI: 10.1210/jendso/bvac136  0.353
2022 Shapira SN, Naji A, Atkinson MA, Powers AC, Kaestner KH. Understanding islet dysfunction in type 2 diabetes through multidimensional pancreatic phenotyping: The Human Pancreas Analysis Program. Cell Metabolism. PMID 36206763 DOI: 10.1016/j.cmet.2022.09.013  0.337
2022 Guo Y, Bian J, Chen A, Wang F, Posgai AL, Schatz DA, Shenkman EA, Atkinson MA. Incidence Trends of New-Onset Diabetes in Children and Adolescents Before and During the COVID-19 Pandemic: Findings from Florida. Diabetes. PMID 36094294 DOI: 10.2337/db22-0549  0.32
2022 Besançon S, Govender D, Sidibé AT, Noble JA, Togo A, Lane JA, Mack SJ, Atkinson MA, Wasserfall CH, Kakkat F, Martin GGN, Ogle GD. Clinical features, biochemistry, and HLA-DRB1 status in youth-onset type 1 diabetes in Mali. Pediatric Diabetes. PMID 36062396 DOI: 10.1111/pedi.13411  0.317
2022 Ismail HM, Cuthbertson D, Gitelman SE, Skyler JS, Steck AK, Rodriguez H, Atkinson M, Nathan BM, Redondo MJ, Herold KC, Evans-Molina C, DiMeglio LA, Sosenko J. The Transition From a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk. Diabetes Care. PMID 35998266 DOI: 10.2337/dc22-0167  0.303
2022 Girdhar K, Huang Q, Chow IT, Vatanen T, Brady C, Raisingani A, Autissier P, Atkinson MA, Kwok WW, Kahn CR, Altindis E. A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120028119. PMID 35878027 DOI: 10.1073/pnas.2120028119  0.306
2022 Dunne JL, Maizel JL, Posgai AL, Atkinson MA, DiMeglio LA. The Women's Leadership Gap in Diabetes: A Call for Equity and Excellence. Diabetes. 70: 1623-1633. PMID 35381061 DOI: 10.2337/db21-0052  0.312
2022 O'Kell AL, Shome M, Qiu J, Williams S, Chung Y, LaBaer J, Atkinson MA, Wasserfall C. Exploration of autoantibody responses in canine diabetes using protein arrays. Scientific Reports. 12: 2490. PMID 35169238 DOI: 10.1038/s41598-022-06599-5  0.368
2022 Kaddis JS, Perry DJ, Vu AN, Rich SS, Atkinson MA, Schatz DA, Roep BO, Brusko TM. Improving the Prediction of Type 1 Diabetes Across Ancestries. Diabetes Care. PMID 35043156 DOI: 10.2337/dc21-1254  0.33
2021 Michels AW, Redondo MJ, Atkinson MA. The pathogenesis, natural history, and treatment of type 1 diabetes: time (thankfully) does not stand still. The Lancet. Diabetes & Endocrinology. PMID 34951951 DOI: 10.1016/S2213-8587(21)00344-2  0.335
2021 Bruggeman BS, Campbell-Thompson M, Filipp SL, Gurka MJ, Atkinson MA, Schatz DA, Jacobsen LM. Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies. Frontiers in Endocrinology. 12: 778912. PMID 34912300 DOI: 10.3389/fendo.2021.778912  0.347
2021 O'Kell AL, Wasserfall C, Guingab-Cagmat J, Webb-Roberston BM, Atkinson MA, Garrett TJ. Targeted metabolomic analysis identifies increased serum levels of GABA and branched chain amino acids in canine diabetes. Metabolomics : Official Journal of the Metabolomic Society. 17: 100. PMID 34775536 DOI: 10.1007/s11306-021-01850-y  0.361
2021 Wu M, Lee MYY, Bahl V, Traum D, Schug J, Kusmartseva I, Atkinson MA, Fan G, Kaestner KH. Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry. Cell Reports. 37: 109919. PMID 34731614 DOI: 10.1016/j.celrep.2021.109919  0.388
2021 Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Human islet T cells are highly reactive to preproinsulin in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34611019 DOI: 10.1073/pnas.2107208118  0.311
2021 Voss MG, Cuthbertson DD, Cleves MM, Xu P, Evans-Molina C, Palmer JP, Redondo MJ, Steck AK, Lundgren M, Larsson H, Moore WV, Atkinson MA, Sosenko JM, Ismail HM. Time to Peak Glucose and Peak C-Peptide During the Progression to Type 1 Diabetes in the Diabetes Prevention Trial and TrialNet Cohorts. Diabetes Care. PMID 34362815 DOI: 10.2337/dc21-0226  0.34
2021 Roep BO, Montero E, van Tienhoven R, Atkinson MA, Schatz DA, Mathieu C. Defining a cure for type 1 diabetes: a call to action. The Lancet. Diabetes & Endocrinology. PMID 34339632 DOI: 10.1016/S2213-8587(21)00181-9  0.366
2021 Hiller H, Beachy DE, Lebowitz JJ, Engler S, Mason JR, Miller DR, Kusmarteva I, Jacobsen LM, Posgai AL, Khoshbouei H, Oram RA, Schatz DA, Hattersley AT, Bodenmiller B, Atkinson MA, et al. Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes. Diabetes. PMID 34035041 DOI: 10.2337/db21-0070  0.361
2021 Beam CA, Beli E, Wasserfall CH, Woerner SE, Legge MT, Evans-Molina C, McGrail KM, Silk R, Grant MB, Atkinson MA, DiMeglio LA. Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes. Diabetologia. PMID 34003304 DOI: 10.1007/s00125-021-05468-6  0.341
2021 Rodriguez-Calvo T, Chen YC, Verchere CB, Haataja L, Arvan P, Leete P, Richardson SJ, Morgan NG, Qian WJ, Pugliese A, Atkinson M, Evans-Molina C, Sims EK. Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes. Diabetes. PMID 33947721 DOI: 10.2337/dbi20-0034  0.361
2021 Atkinson MA, Powers AC. Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? The Lancet. Diabetes & Endocrinology. PMID 33838106 DOI: 10.1016/S2213-8587(21)00087-5  0.347
2021 Campbell-Thompson M, Butterworth EA, Boatwright JL, Nair MA, Nasif LH, Nasif K, Revell AY, Riva A, Mathews CE, Gerling IC, Schatz DA, Atkinson MA. Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes. Scientific Reports. 11: 6562. PMID 33753784 DOI: 10.1038/s41598-021-85659-8  0.31
2021 Nandedkar-Kulkarni N, Esakov E, Gregg B, Atkinson MA, Rogers DG, Horner JD, Singer K, Lundy SK, Felton JL, Al-Huniti T, Kalinoski AN, Morran MP, Gupta NK, Bretz JD, Balaji S, et al. Insulin Receptor-Expressing T Cells Appear in Individuals at Risk for Type 1 Diabetes and Can Move into the Pancreas in C57BL/6 Transgenic Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 33658296 DOI: 10.4049/jimmunol.1900357  0.305
2021 Lin A, Mack JA, Bruggeman B, Jacobsen LM, Posgai AL, Wasserfall CH, Brusko TM, Atkinson MA, Gitelman SE, Gottlieb PA, Gurka MJ, Mathews CE, Schatz DA, Haller MJ. Low-dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report. Diabetes. PMID 33632742 DOI: 10.2337/db20-1103  0.305
2021 Ciecko AE, Foda B, Barr JY, Ramanathan S, Atkinson MA, Serreze DV, Geurts AM, Lieberman SM, Chen YG. Interleukin-27 is essential for type 1 diabetes development and Sjögren syndrome-like inflammation. Cell Reports. 34: 108725. PMID 33535031 DOI: 10.1016/j.celrep.2021.108725  0.328
2021 Balzano-Nogueira L, Ramirez R, Zamkovaya T, Dailey J, Ardissone AN, Chamala S, Serrano-Quílez J, Rubio T, Haller MJ, Concannon P, Atkinson MA, Schatz DA, Triplett EW, Conesa A. Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes. Genome Biology. 22: 39. PMID 33478573 DOI: 10.1186/s13059-021-02262-w  0.359
2021 Petrelli A, Atkinson MA, Pietropaolo M, Giannoukakis N. Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes. Diabetes. 70: 313-322. PMID 33472941 DOI: 10.2337/dbi20-0026  0.345
2021 Ross JJ, Wasserfall CH, Bacher R, Perry DJ, McGrail K, Posgai AL, Dong X, Muir A, Li X, Campbell-Thompson M, Brusko TM, Schatz DA, Haller MJ, Atkinson MA. Exocrine Pancreatic Enzymes Are a Serological Biomarker for Type 1 Diabetes Staging and Pancreas Size. Diabetes. PMID 33441381 DOI: 10.2337/db20-0995  0.364
2021 Williams MD, Bacher R, Perry DJ, Grace CR, McGrail KM, Posgai AL, Muir A, Chamala S, Haller MJ, Schatz DA, Brusko TM, Atkinson MA, Wasserfall CH. Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis. Diabetes. PMID 33419759 DOI: 10.2337/db20-0937  0.33
2020 Foster TP, Bruggeman B, Campbell-Thompson M, Atkinson MA, Haller MJ, Schatz DA. Exocrine Pancreas Dysfunction in Type 1 Diabetes. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 26: 1505-1513. PMID 33471743 DOI: 10.4158/Ep-2020-0295  0.365
2020 O'Kell AL, Wasserfall CH, Henthorn PS, Atkinson MA, Hess RS. Evaluation for type 1 diabetes associated autoantibodies in diabetic and non-diabetic Australian terriers and Samoyeds. Canine Medicine and Genetics. 7: 10. PMID 33323126 DOI: 10.1186/s40575-020-00089-5  0.38
2020 Tang X, Kusmartseva I, Kulkarni S, Posgai A, Speier S, Schatz DA, Haller MJ, Campbell-Thompson M, Wasserfall CH, Roep BO, Kaddis JS, Atkinson MA. Image-based machine learning algorithms for disease characterization in the human type 1 diabetes pancreas. The American Journal of Pathology. PMID 33307036 DOI: 10.1016/j.ajpath.2020.11.010  0.383
2020 Atkinson MA, Campbell-Thompson M, Kusmartseva I, Kaestner KH. Organisation of the human pancreas in health and in diabetes. Diabetologia. 63: 1966-1973. PMID 32894306 DOI: 10.1007/S00125-020-05203-7  0.339
2020 Walejko JM, Chelliah A, Keller-Wood M, Wasserfall C, Atkinson M, Gregg A, Edison AS. Diabetes Leads to Alterations in Normal Metabolic Transitions of Pregnancy as Revealed by Time-Course Metabolomics. Metabolites. 10. PMID 32867274 DOI: 10.3390/Metabo10090350  0.328
2020 Jacobsen L, Bundy B, Greco M, Schatz D, Atkinson M, Brusko T, Mathews C, Herold KC, Gitelman S, Krischer J, Haller M. Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes. Diabetes Technology & Therapeutics. PMID 32833543 DOI: 10.1089/Dia.2020.0305  0.344
2020 Carr ALJ, Perry DJ, Lynam AL, Chamala S, Flaxman CS, Sharp SA, Ferrat LA, Jones AG, Beery ML, Jacobsen LM, Wasserfall CH, Campbell-Thompson ML, Kusmartseva I, Posgai A, Schatz DA, ... Atkinson MA, et al. Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 32634859 DOI: 10.1111/Dme.14361  0.339
2020 Qadir MMF, Álvarez-Cubela S, Weitz J, Panzer JK, Klein D, Moreno-Hernández Y, Cechin S, Tamayo A, Almaça J, Hiller H, Beery M, Kusmartseva I, Atkinson M, Speier S, Ricordi C, et al. Long-term culture of human pancreatic slices as a model to study real-time islet regeneration. Nature Communications. 11: 3265. PMID 32601271 DOI: 10.1038/S41467-020-17040-8  0.362
2020 Cook DP, Cunha JPMCM, Martens PJ, Sassi G, Mancarella F, Ventriglia G, Sebastiani G, Vanherwegen AS, Atkinson MA, Van Huynegem K, Steidler L, Caluwaerts S, Rottiers P, Teyton L, Dotta F, et al. Intestinal Delivery of Proinsulin and IL-10 via Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis. Frontiers in Immunology. 11: 1103. PMID 32582188 DOI: 10.3389/Fimmu.2020.01103  0.365
2020 de Boer P, Pirozzi NM, Wolters AHG, Kuipers J, Kusmartseva I, Atkinson MA, Campbell-Thompson M, Giepmans BNG. Large-scale electron microscopy database for human type 1 diabetes. Nature Communications. 11: 2475. PMID 32424134 DOI: 10.1038/S41467-020-16287-5  0.391
2020 Panzer JK, Hiller H, Cohrs CM, Almaça J, Enos SJ, Beery M, Cechin S, Drotar DM, Weitz JR, Santini J, Huber MK, Muhammad Fahd Qadir M, Pastori RL, Domínguez-Bendala J, Phelps EA, Atkinson MA, et al. Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis. Jci Insight. 5. PMID 32324170 DOI: 10.1172/Jci.Insight.134525  0.318
2020 Sims EK, Geyer S, Johnson SB, Libman I, Jacobsen LM, Boulware D, Rafkin LE, Matheson D, Atkinson MA, Rodriguez H, Spall M, Larsson HE, Wherrett DK, Greenbaum CJ, Krischer J, et al. Erratum. Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention. Diabetes Care 2019;42:2228-2236. Diabetes Care. PMID 32132004 DOI: 10.2337/Dc20-Er04  0.359
2020 Sims EK, Geyer S, Johnson SB, Libman I, Jacobsen LM, Boulware D, Rafkin LE, Matheson D, Atkinson MA, Rodriguez H, Spall M, Larsson HE, Wherrett DK, Greenbaum CJ, Krischer J, et al. Erratum: Who is enrolling? The path to monitoring in type 1 diabetes trialnet’s pathway to prevention (Diabetes care (2019) 42 (2228–2236) DOI: 10.2337/dc19-0593) Diabetes Care. 43. DOI: 10.2337/Dc20Er04  0.338
2020 KULKARNI SS, BUTLER AE, ATKINSON MA. 2062-P: Pancreatic Inflammation Implicates Increased Cellular Plasticity in the Pancreatic Duct Glands in Type 1 Diabetes Diabetes. 69: 2062-P. DOI: 10.2337/db20-2062-p  0.3
2020 O’Kell AL, Wasserfall CH, Henthorn PS, Atkinson MA, Hess RS. Evaluation for type 1 diabetes associated autoantibodies in diabetic and non-diabetic Australian terriers and Samoyeds Canine Medicine and Genetics. 7. DOI: 10.1186/s40575-020-00089-5  0.369
2019 Redondo MJ, Sosenko J, Libman I, McVean JJF, Tosur M, Atkinson MA, Becker D, Geyer S. Single Islet Autoantibody at Diagnosis of Clinical Type 1 Diabetes is Associated with Older Age and Insulin Resistance. The Journal of Clinical Endocrinology and Metabolism. PMID 31867614 DOI: 10.1210/Clinem/Dgz296  0.343
2019 Shapiro MR, Wasserfall CH, McGrail SM, Posgai AL, Bacher R, Muir A, Haller MJ, Schatz DA, Wesley JD, von Herrath M, Hagopian WA, Speake C, Atkinson MA, Brusko TM. Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis. Diabetes. PMID 31826866 DOI: 10.2337/Db19-0942  0.313
2019 Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, et al. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. PMID 31753960 DOI: 10.2337/Dc19-0880  0.336
2019 Kusmartseva I, Beery M, Hiller H, Padilla M, Selman S, Posgai A, Nick HS, Campbell-Thompson M, Schatz DA, Haller MJ, Wasserfall CH, Atkinson MA. Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues. Diabetes. PMID 31597639 DOI: 10.2337/Db19-0554  0.356
2019 Sims EK, Geyer S, Johnson SB, Libman I, Jacobsen LM, Boulware D, Rafkin LE, Matheson D, Atkinson MA, Rodriguez H, Spall M, Larsson HE, Wherrett DK, Greenbaum CJ, Krischer J, et al. Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention. Diabetes Care. PMID 31558546 DOI: 10.2337/Dc19-0593  0.347
2019 Kehlenbrink S, Jaacks LM, Perone SA, Ansbro É, Ashbourne E, Atkinson C, Atkinson M, Atun R, Besançon S, Boulle P, Bygrave H, Caballero E, Cooper K, Cristello A, Digovich K, et al. Diabetes in humanitarian crises: the Boston Declaration. The Lancet Diabetes & Endocrinology. 7: 590-592. PMID 31178312 DOI: 10.1016/S2213-8587(19)30197-4  0.46
2019 Redondo MJ, Evans-Molina C, Steck AK, Atkinson MA, Sosenko J. The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes. Diabetes Care. PMID 31167894 DOI: 10.2337/Dc19-0102  0.4
2019 Shapiro MR, Atkinson MA, Brusko TM. Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes. Current Opinion in Endocrinology, Diabetes, and Obesity. PMID 31145130 DOI: 10.1097/Med.0000000000000484  0.302
2019 Kaestner KH, Powers AC, Naji A, Atkinson MA. NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP). Diabetes. PMID 31127054 DOI: 10.2337/Db19-0058  0.391
2019 Lewis JS, Stewart JM, Marshall GP, Carstens MR, Zhang Y, Dolgova NV, Xia C, Brusko TM, Wasserfall CH, Clare-Salzler MJ, Atkinson MA, Keselowsky BG. Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model. Acs Biomaterials Science & Engineering. 5: 2631-2646. PMID 31119191 DOI: 10.1021/Acsbiomaterials.9B00332  0.39
2019 Beery ML, Jacobsen LM, Atkinson MA, Butler AE, Campbell-Thompson M. Islet amyloidosis in a child with type 1 diabetes. Islets. 1-6. PMID 31084520 DOI: 10.1080/19382014.2019.1599707  0.392
2019 Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Geyer SM, Warnock MV, Miller JL, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, et al. Low-dose Anti-Thymocyte Globulin Preserves C-Peptide and Reduces A1c in New Onset Type 1 Diabetes: Two Year Clinical Trial Data. Diabetes. PMID 30967424 DOI: 10.2337/Db19-0057  0.318
2019 O'Kell AL, Garrett TJ, Wasserfall C, Atkinson MA. Untargeted metabolomic analysis in non-fasted diabetic dogs by UHPLC-HRMS. Metabolomics : Official Journal of the Metabolomic Society. 15: 15. PMID 30830416 DOI: 10.1007/S11306-019-1477-6  0.363
2019 Thompson PJ, Shah A, Ntranos V, Van Gool F, Atkinson M, Bhushan A. Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes. Cell Metabolism. PMID 30799288 DOI: 10.1016/J.Cmet.2019.01.021  0.393
2019 Wang YJ, Traum D, Schug J, Gao L, Liu C, Atkinson MA, Powers AC, Feldman MD, Naji A, Chang KM, Kaestner KH. Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes. Cell Metabolism. PMID 30713110 DOI: 10.1016/J.Cmet.2019.01.003  0.36
2019 Damond N, Engler S, Zanotelli VRT, Schapiro D, Wasserfall CH, Kusmartseva I, Nick HS, Thorel F, Herrera PL, Atkinson MA, Bodenmiller B. A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry. Cell Metabolism. PMID 30713109 DOI: 10.1016/J.Cmet.2018.11.014  0.306
2019 Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Dahl-Jørgensen K, Flodström-Tullberg M, Hyöty H, Insel RA, Lernmark Å, Lloyd RE, Morgan NG, Pugliese A. Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes. Diabetologia. PMID 30675626 DOI: 10.1007/S00125-019-4811-7  0.361
2019 Onengut-Gumuscu S, Chen WM, Robertson CC, Bonnie JK, Farber E, Zhu Z, Oksenberg JR, Brant SR, Bridges SL, Edberg JC, Kimberly RP, Gregersen PK, Rewers MJ, Steck AK, Black MH, ... ... Atkinson MA, et al. Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. Diabetes Care. PMID 30659077 DOI: 10.2337/Dc18-1727  0.302
2019 Campbell-Thompson ML, Filipp SL, Grajo JR, Nambam B, Beegle R, Middlebrooks EH, Gurka MJ, Atkinson MA, Schatz DA, Haller MJ. Relative Pancreas Volume Is Reduced in First-Degree Relatives of Patients With Type 1 Diabetes. Diabetes Care. 42: 281-287. PMID 30552130 DOI: 10.2337/Dc18-1512  0.355
2019 Atkinson MA, Roep BO, Posgai A, Wheeler DCS, Peakman M. The challenge of modulating β-cell autoimmunity in type 1 diabetes. The Lancet. Diabetes & Endocrinology. 7: 52-64. PMID 30528099 DOI: 10.1016/S2213-8587(18)30112-8  0.346
2018 Redondo MJ, Steck AK, Sosenko J, Anderson M, Antinozzi P, Michels A, Wentworth JM, Atkinson MA, Pugliese A, Geyer S. Transcription Factor 7-Like 2 () Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes. Diabetes Care. PMID 30275285 DOI: 10.2337/Dc18-0861  0.376
2018 Redondo MJ, Geyer S, Steck AK, Sharp S, Wentworth JM, Weedon MN, Antinozzi P, Sosenko J, Atkinson M, Pugliese A, Oram RA. A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk. Diabetes Care. PMID 30002199 DOI: 10.2337/Dc18-0087  0.42
2018 Canzano JS, Nasif LH, Butterworth EA, Fu DA, Atkinson MA, Campbell-Thompson M. Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155418778546. PMID 29771178 DOI: 10.1369/0022155418778546  0.364
2018 Greenbaum CJ, Speake C, Krischer J, Buckner J, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA. Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Diabetes. PMID 29769238 DOI: 10.2337/Db18-0065  0.353
2018 Bingley PJ, Wherrett DK, Shultz A, Rafkin LE, Atkinson MA, Greenbaum CJ. Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes. Diabetes Care. 41: 653-661. PMID 29559451 DOI: 10.2337/dc17-0806  0.314
2018 Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, ... ... Atkinson M, et al. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Reports. 22: 2667-2676. PMID 29514095 DOI: 10.1016/J.Celrep.2018.02.032  0.393
2018 Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. The Journal of Clinical Investigation. PMID 29438107 DOI: 10.1172/Jci97739  0.341
2018 Smith MJ, Rihanek M, Wasserfall C, Mathews CE, Atkinson MA, Gottlieb PA, Cambier JC. Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles. Diabetes. PMID 29343548 DOI: 10.2337/Db17-0937  0.327
2018 Bosi E, Geyer S, Sosenko J, Becker DJ, Battaglia M, Ismail HM, Atkinson MA, Philipson LH, Palmer JP, Evans-Molina C. Metabolic Markers Associated with Increased Risk for Progression from Single to Multiple Autoantibodies in Type 1 Diabetes Relatives Diabetes. 67. DOI: 10.2337/Db18-94-Or  0.302
2018 KULKARNI SS, ATKINSON MA, BUTLER A. No Compensatory Increase in Non-ß Hormone Expressing Cells in the Pancreatic Duct Glands in Type 1 Diabetes Diabetes. 67: 2134-P. DOI: 10.2337/DB18-2134-P  0.341
2017 Sanyoura M, Jacobsen L, Carmody D, Gaudio DD, Alkorta-Aranburu G, Arndt K, Hu YY, Kobiernicki F, Kusmartseva I, Atkinson MA, Philipson LH, Schatz D, Campbell-Thompson M, Greeley SAW. Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. The Journal of Clinical Endocrinology and Metabolism. PMID 28938416 DOI: 10.1210/Jc.2017-01159  0.376
2017 Chen J, Chernatynskaya AV, Li JW, Kimbrell MR, Cassidy RJ, Perry DJ, Muir AB, Atkinson MA, Brusko TM, Mathews CE. T cells display mitochondria hyperpolarization in human type 1 diabetes. Scientific Reports. 7: 10835. PMID 28883439 DOI: 10.1038/S41598-017-11056-9  0.348
2017 Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M. Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata. Cell Metabolism. 26: 568-575.e3. PMID 28877460 DOI: 10.1016/J.Cmet.2017.08.013  0.39
2017 Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM. Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials. Diabetes Care. PMID 28860125 DOI: 10.2337/Dc17-0916  0.333
2017 O'Kell AL, Garrett TJ, Wasserfall C, Atkinson MA. Untargeted metabolomic analysis in naturally occurring canine diabetes mellitus identifies similarities to human Type 1 Diabetes. Scientific Reports. 7: 9467. PMID 28842637 DOI: 10.1038/S41598-017-09908-5  0.355
2017 Rodriguez-Calvo T, Atkinson M, Herrath MGv. Response to Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345. Diabetes. 66. PMID 28830918 DOI: 10.2337/Dbi17-0029  0.454
2017 Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, ... ... Atkinson MA, et al. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. 23: 1004. PMID 28777787 DOI: 10.1038/nm0817-1004a  0.342
2017 Haller M, Atkinson M, Schatz D. More on Intralymphatic Injection of Autoantigen in Type 1 Diabetes. The New England Journal of Medicine. 377: 403-403. PMID 28748691 DOI: 10.1056/Nejmc1703468  0.461
2017 Rodriguez-Calvo T, Atkinson M, Herrath Mv. β-Cell mass versus function in type 1 diabetes mellitus: truth or dare? Nature Reviews Endocrinology. 13: 1-1. PMID 28685769 DOI: 10.1038/Nrendo.2017.83  0.445
2017 O'Kell AL, Wasserfall C, Catchpole B, Davison LJ, Hess RS, Kushner JA, Atkinson MA. Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked? Diabetes. 66: 1443-1452. PMID 28533295 DOI: 10.2337/Db16-1551  0.414
2017 Ratiu JJ, Racine JJ, Hasham MG, Wang Q, Branca JA, Chapman HD, Zhu J, Donghia N, Philip V, Schott WH, Wasserfall C, Atkinson MA, Mills KD, Leeth CM, Serreze DV. Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28461573 DOI: 10.4049/Jimmunol.1700024  0.308
2017 Posgai AL, Wasserfall CH, Kwon KC, Daniell H, Schatz DA, Atkinson MA. Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice. Scientific Reports. 7: 42372. PMID 28205558 DOI: 10.1038/Srep42372  0.316
2017 Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, ... ... Atkinson MA, et al. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Nature Medicine. 23: 264. PMID 28170374 DOI: 10.1038/Nm0217-264A  0.342
2017 Li X, Campbell-Thompson M, Wasserfall CH, McGrail K, Posgai A, Schultz AR, Brusko TM, Shuster J, Liang F, Muir A, Schatz D, Haller MJ, Atkinson MA. Serum Trypsinogen Levels in Type 1 Diabetes. Diabetes Care. PMID 28115475 DOI: 10.2337/Dc16-1774  0.362
2017 Campbell-Thompson ML, Atkinson MA, Butler AE, Giepmans BN, von Herrath MG, Hyöty H, Kay TW, Morgan NG, Powers AC, Pugliese A, Richardson SJ, In't Veld PA. Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Diabetologia. PMID 28070616 DOI: 10.1007/S00125-016-4195-X  0.324
2017 Lin A, Mathews C, Haller M, Brusko T, Atkinson M, Flynn R. 2431 Journal of Clinical and Translational Science. 1: 37-37. DOI: 10.1017/cts.2017.136  0.338
2016 Ziegler AG, Bonifacio E, Powers AC, Todd JA, Harrison LC, Atkinson MA. Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease. Diabetes. 65: 3233-3239. PMID 27959859 DOI: 10.2337/Db16-0687  0.386
2016 Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Islet-derived CD4 T-cells targeting proinsulin in human autoimmune diabetes. Diabetes. PMID 27920090 DOI: 10.2337/Db16-1025  0.389
2016 Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity. Diabetologia. PMID 27785529 DOI: 10.1007/S00125-016-4144-8  0.318
2016 Bian X, Wasserfall C, Wallstrom G, Wang J, Wang H, Barker K, Schatz D, Atkinson M, Qiu J, LaBaer J. Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays. Journal of Proteome Research. PMID 27690455 DOI: 10.1021/Acs.Jproteome.6B00354  0.431
2016 Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG. Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes. Diabetologia. PMID 27506584 DOI: 10.1007/S00125-016-4067-4  0.327
2016 Burke GW, Posgai AL, Wasserfall CH, Atkinson MA, Pugliese A. Raising Awareness: The Need to Promote Allocation of Pancreata from Rare Non-Diabetic Donors with Pancreatic Islet Autoimmunity to Type 1 Diabetes Research. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27460917 DOI: 10.1111/Ajt.13983  0.339
2016 Jacobsen LM, Atkinson MA, Campbell-Thompson M, Schatz DA. Presumptive Type 1 Diabetes With Comorbidities and Rapid Progression Despite Numerous Insulin-Positive Islets. Diabetes Care. 39: 1292-4. PMID 27330131 DOI: 10.2337/Dc16-0737  0.362
2016 Endesfelder D, Engel M, Davis-Richardson AG, Ardissone AN, Achenbach P, Hummel S, Winkler C, Atkinson M, Schatz D, Triplett E, Ziegler AG, zu Castell W. Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production. Microbiome. 4: 17. PMID 27114075 DOI: 10.1186/S40168-016-0163-4  0.421
2015 Campbell-Thompson M, Fu A, Kaddis JS, Wasserfall C, Schatz DA, Pugliese A, Atkinson MA. Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes. Diabetes. PMID 26581594 DOI: 10.2337/Db15-0779  0.389
2015 Gagliani N, Jofra T, Posgai AL, Atkinson MA, Battaglia M. Immune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD Mice. Plos One. 10: e0142318. PMID 26580221 DOI: 10.1371/Journal.Pone.0142318  0.381
2015 Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26546129 DOI: 10.1096/Fj.15-279810  0.324
2015 Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano C, Yang LJ, et al. Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice. Genetics & Epigenetics. 7: 5-17. PMID 26512207 DOI: 10.4137/GEG.S29696  0.334
2015 Bian X, Wallstrom G, Davis A, Wang J, Park J, Throop A, Steel J, Yu X, Wasserfall C, Schatz D, Atkinson M, Qiu J, LaBaer J. Immunoproteomic Profiling of Anti-Viral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays. Diabetes. PMID 26450993 DOI: 10.2337/Db15-0179  0.326
2015 Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, Greenbaum CJ, Herold KC, Krischer JP, Lernmark Å, Ratner RE, Rewers MJ, Schatz DA, Skyler JS, Sosenko JM, et al. Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care. 38: 1964-74. PMID 26404926 DOI: 10.2337/Dc15-1419  0.33
2015 Campbell-Thompson ML, Kaddis JS, Wasserfall C, Haller MJ, Pugliese A, Schatz DA, Shuster JJ, Atkinson MA. The influence of type 1 diabetes on pancreatic weight. Diabetologia. PMID 26358584 DOI: 10.1007/S00125-015-3752-Z  0.342
2015 Li X, Atkinson MA. The role for gut permeability in the pathogenesis of type 1 diabetes--a solid or leaky concept? Pediatric Diabetes. 16: 485-92. PMID 26269193 DOI: 10.1111/Pedi.12305  0.31
2015 Mathews CE, Xue S, Posgai A, Lightfoot YL, Li X, Lin A, Wasserfall C, Haller MJ, Schatz D, Atkinson MA. Acute Versus Progressive Onset of Diabetes in NOD Mice - Potential Implications for Therapeutic Interventions in Type 1 Diabetes. Diabetes. PMID 26216853 DOI: 10.2337/Db15-0449  0.384
2015 Xue S, Posgai A, Wasserfall C, Myhr C, Campbell-Thompson M, Mathews CE, Brusko T, Rabinovitch A, Savinov A, Battaglia M, Schatz D, Haller M, Atkinson M. Combination therapy reverses hyperglycemia in NOD mice with established type 1 diabetes. Diabetes. PMID 26185279 DOI: 10.2337/Db15-0164  0.325
2015 Kaddis JS, Pugliese A, Atkinson MA. A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository? Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 290-5. PMID 26087339 DOI: 10.1097/Med.0000000000000171  0.345
2015 Atkinson MA, von Herrath M, Powers AC, Clare-Salzler M. Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease. Diabetes Care. 38: 979-88. PMID 25998290 DOI: 10.2337/Dc15-0144  0.375
2015 Lewis JS, Dolgova NV, Zhang Y, Xia CQ, Wasserfall CH, Atkinson MA, Clare-Salzler MJ, Keselowsky BG. A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice. Clinical Immunology (Orlando, Fla.). PMID 25842187 DOI: 10.1016/J.Clim.2015.03.023  0.318
2015 Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, ... ... Atkinson MA, et al. Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care. 38: 329-32. PMID 25519450 DOI: 10.2337/Dc14-0850  0.342
2015 Haller MJ, Gitelman SE, Gottlieb PA, Michels AW, Rosenthal SM, Shuster JJ, Zou B, Brusko TM, Hulme MA, Wasserfall CH, Mathews CE, Atkinson MA, Schatz DA. Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes. The Journal of Clinical Investigation. 125: 448-55. PMID 25500887 DOI: 10.1172/Jci78492  0.304
2015 Kleffel S, Vergani A, Tezza S, Ben Nasr M, Niewczas MA, Wong S, Bassi R, D'Addio F, Schatton T, Abdi R, Atkinson M, Sayegh MH, Wen L, Wasserfall CH, O'Connor KC, et al. Interleukin-10+ regulatory B cells arise within antigen-experienced CD40+ B cells to maintain tolerance to islet autoantigens. Diabetes. 64: 158-71. PMID 25187361 DOI: 10.2337/Db13-1639  0.414
2014 Atkinson MA. Losing a grip on the notion of β-cell specificity for immune responses in type 1 diabetes: can we handle the truth? Diabetes. 63: 3572-4. PMID 25342726 DOI: 10.2337/Db14-1069  0.367
2014 Pugliese A, Vendrame F, Reijonen H, Atkinson MA, Campbell-Thompson M, Burke GW. New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation Current Diabetes Reports. 14: 530. PMID 25142715 DOI: 10.1007/S11892-014-0530-0  0.324
2014 Purwana I, Zheng J, Li X, Deurloo M, Son DO, Zhang Z, Liang C, Shen E, Tadkase A, Feng ZP, Li Y, Hasilo C, Paraskevas S, Bortell R, Greiner DL, ... Atkinson M, et al. GABA promotes human β-cell proliferation and modulates glucose homeostasis. Diabetes. 63: 4197-205. PMID 25008178 DOI: 10.2337/Db14-0153  0.317
2014 Radichev IA, Maneva-Radicheva LV, Amatya C, Parker C, Ellefson J, Wasserfall C, Atkinson M, Burn P, Savinov AY. Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development. Diabetes. 63: 3470-82. PMID 24848066 DOI: 10.2337/Db14-0213  0.465
2014 Robert S, Gysemans C, Takiishi T, Korf H, Spagnuolo I, Sebastiani G, Van Huynegem K, Steidler L, Caluwaerts S, Demetter P, Wasserfall CH, Atkinson MA, Dotta F, Rottiers P, Van Belle TL, et al. Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice. Diabetes. 63: 2876-87. PMID 24677716 DOI: 10.2337/Db13-1236  0.33
2014 Dunne JL, Triplett EW, Gevers D, Xavier R, Insel R, Danska J, Atkinson MA. The intestinal microbiome in type 1 diabetes. Clinical and Experimental Immunology. 177: 30-7. PMID 24628412 DOI: 10.1111/Cei.12321  0.319
2014 Endesfelder D, zu Castell W, Ardissone A, Davis-Richardson AG, Achenbach P, Hagen M, Pflueger M, Gano KA, Fagen JR, Drew JC, Brown CT, Kolaczkowski B, Atkinson M, Schatz D, Bonifacio E, et al. Compromised gut microbiota networks in children with anti-islet cell autoimmunity. Diabetes. 63: 2006-14. PMID 24608442 DOI: 10.2337/Db13-1676  0.393
2014 Atkinson MA. Pancreatic biopsies in type 1 diabetes: revisiting the myth of Pandora's box. Diabetologia. 57: 656-9. PMID 24442510 DOI: 10.1007/S00125-013-3159-7  0.338
2014 Giannopoulou EZ, Puff R, Beyerlein A, von Luettichau I, Boerschmann H, Schatz D, Atkinson M, Haller MJ, Egger D, Burdach S, Ziegler AG. Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial. Pediatric Diabetes. 15: 100-9. PMID 24102806 DOI: 10.1111/Pedi.12072  0.396
2014 Atkinson MA, Eisenbarth GS, Michels AW. Type 1 diabetes. Lancet (London, England). 383: 69-82. PMID 23890997 DOI: 10.1016/S0140-6736(13)60591-7  0.379
2014 Guleria I, Bupp MG, Dada S, Fife BT, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH. Corrigendum to 'Mechanisms of PDL1-mediated regulation of autoimmune diabetes' [Clin. Immunol. 125 (2007) 16-25] Clinical Immunology. 150: 134. DOI: 10.1016/J.Clim.2013.09.004  0.4
2013 Atkinson MA. Trying to make a difference for those with Type 1 diabetes: a lesson in patience as well as a willingness to fail mightily. Expert Review of Endocrinology & Metabolism. 8: 323-327. PMID 30736146 DOI: 10.1586/17446651.2013.811869  0.393
2013 Garrigan E, Belkin NS, Alexander JJ, Han Z, Seydel F, Carter J, Atkinson M, Wasserfall C, Clare-Salzler MJ, Amick MA, Litherland SA. Persistent STAT5 phosphorylation and epigenetic dysregulation of GM-CSF and PGS2/COX2 expression in Type 1 diabetic human monocytes. Plos One. 8: e76919. PMID 24204704 DOI: 10.1371/Journal.Pone.0076919  0.316
2013 Miersch S, Bian X, Wallstrom G, Sibani S, Logvinenko T, Wasserfall CH, Schatz D, Atkinson M, Qiu J, LaBaer J. Serological autoantibody profiling of type 1 diabetes by protein arrays. Journal of Proteomics. 94: 486-96. PMID 24148850 DOI: 10.1016/J.Jprot.2013.10.018  0.374
2013 Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. Response to comments on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604. Diabetes. 62: e19-22. PMID 24065800 DOI: 10.2337/Db13-0996  0.422
2013 Rowe P, Wasserfall C, Croker B, Campbell-Thompson M, Pugliese A, Atkinson M, Schatz D. Increased Complement Activation in Human Type 1 Diabetes Pancreata Diabetes Care. 36: 3815-3817. PMID 24041678 DOI: 10.2337/Dc13-0203  0.424
2013 Campbell-Thompson ML, Atkinson MA, Butler AE, Chapman NM, Frisk G, Gianani R, Giepmans BN, von Herrath MG, Hyöty H, Kay TW, Korsgren O, Morgan NG, Powers AC, Pugliese A, Richardson SJ, et al. The diagnosis of insulitis in human type 1 diabetes. Diabetologia. 56: 2541-3. PMID 24006089 DOI: 10.1007/S00125-013-3043-5  0.352
2013 Beran D, Yudkin JS, Atkinson MA. Global reality of type 1 diabetes care in 2013. Diabetes Care. 36: e144. PMID 23970723 DOI: 10.2337/Dc13-0744  0.3
2013 Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, Wasserfall C, Atkinson MA, Brekken RA, Pullen N, Arch RH, Bluestone JA. Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes. 62: 2870-8. PMID 23835340 DOI: 10.2337/Db12-1619  0.341
2013 Gagliani N, Jofra T, Valle A, Stabilini A, Morsiani C, Gregori S, Deng S, Rothstein DM, Atkinson M, Kamanaka M, Flavell RA, Roncarolo MG, Battaglia M. Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 1963-75. PMID 23834659 DOI: 10.1111/Ajt.12333  0.342
2013 Tang DQ, Shun L, Koya V, Sun Y, Wang Q, Wang H, Li SW, Sun Y, Purich DL, Zhang C, Hansen B, Qian K, Atkinson M, Phillips MI, Yang LJ. Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of murine model of type 1 diabetes. American Journal of Translational Research. 5: 184-99. PMID 23573363  0.331
2013 Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes. 62: 2595-604. PMID 23524641 DOI: 10.2337/Db12-1686  0.352
2013 Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, et al. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice. Plos One. 8: e54712. PMID 23405091 DOI: 10.1371/Journal.Pone.0054712  0.415
2013 Zhang Q, Fillmore TL, Schepmoes AA, Clauss TR, Gritsenko MA, Mueller PW, Rewers M, Atkinson MA, Smith RD, Metz TO. Serum proteomics reveals systemic dysregulation of innate immunity in type 1 diabetes. The Journal of Experimental Medicine. 210: 191-203. PMID 23277452 DOI: 10.1084/Jem.20111843  0.352
2013 Davoodi-Semiromi A, Wasserfall CH, Hassanzadeh A, Cooper-DeHoff RM, Wabitsch M, Atkinson M. Influence of Tyrphostin AG490 on the expression of diabetes-associated markers in human adipocytes. Immunogenetics. 65: 83-90. PMID 23081744 DOI: 10.1007/S00251-012-0659-4  0.427
2013 Atkinson MA. Trying to make a difference for those with Type 1 diabetes: A lesson in patience as well as a willingness to fail mightily Expert Review of Endocrinology and Metabolism. 8: 323-327. DOI: 10.1586/17446651.2013.811869  0.367
2013 Pugliese A, Campbell-Thompson M, Staeva T, Atkinson MA. The JDRF network for the pancreatic organ donor with diabetes (nPOD): A novel resource and study approach in type 1 diabetes research Diabetes and Viruses. 2147483647: 245-255. DOI: 10.1007/978-1-4614-4051-2_24  0.357
2012 Beran D, Basey M, Wirtz V, Kaplan W, Atkinson M, Yudkin JS. On the road to the insulin centenary. Lancet (London, England). 380: 1648. PMID 23141616 DOI: 10.1016/S0140-6736(12)61950-3  0.369
2012 Atkinson MA. The pathogenesis and natural history of type 1 diabetes. Cold Spring Harbor Perspectives in Medicine. 2. PMID 23125199 DOI: 10.1101/Cshperspect.A007641  0.356
2012 Atkinson MA, Chervonsky A. Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease Diabetologia. 55: 2868-2877. PMID 22875196 DOI: 10.1007/S00125-012-2672-4  0.319
2012 Davoodi-Semiromi A, Hassanzadeh A, Wasserfall CH, Droney A, Atkinson M. Tyrphostin AG490 agent modestly but significantly prevents onset of type 1 in NOD mouse; implication of immunologic and metabolic effects of a Jak-Stat pathway inhibitor. Journal of Clinical Immunology. 32: 1038-1047. PMID 22661285 DOI: 10.1007/S10875-012-9707-Y  0.355
2012 Davoodi-Semiromi A, Wasserfall CH, Xia CQ, Cooper-DeHoff RM, Wabitsch M, Clare-Salzler M, Atkinson M. The tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD mice. Plos One. 7: e36079. PMID 22615750 DOI: 10.1371/Journal.Pone.0036079  0.467
2012 Campbell-Thompson M, Wasserfall C, Kaddis J, Albanese-O'Neill A, Staeva T, Nierras C, Moraski J, Rowe P, Gianani R, Eisenbarth G, Crawford J, Schatz D, Pugliese A, Atkinson M. Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes. Diabetes/Metabolism Research and Reviews. 28: 608-17. PMID 22585677 DOI: 10.1002/Dmrr.2316  0.434
2012 Wang M, Racine JJ, Song X, Li X, Nair I, Liu H, Avakian-Mansoorian A, Johnston HF, Liu C, Shen C, Atkinson M, Todorov I, Kandeel F, Forman S, Wilson B, et al. Mixed chimerism and growth factors augment β cell regeneration and reverse late-stage type 1 diabetes. Science Translational Medicine. 4: 133ra59. PMID 22572882 DOI: 10.1126/Scitranslmed.3003835  0.432
2012 Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, et al. Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. The Journal of Clinical Investigation. 122: 1717-25. PMID 22484814 DOI: 10.1089/Dia.2013.1510  0.487
2012 Coppieters KT, Dotta F, Amirian N, Campbell PD, Kay TW, Atkinson MA, Roep BO, von Herrath MG. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. The Journal of Experimental Medicine. 209: 51-60. PMID 22213807 DOI: 10.1084/Jem.20111187  0.337
2012 Hulme MA, Wasserfall CH, Atkinson MA, Brusko TM. Central role for interleukin-2 in type 1 diabetes. Diabetes. 61: 14-22. PMID 22187370 DOI: 10.2337/Db11-1213  0.358
2012 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited (Diabetes (2011) 60, (1370-1379)) Diabetes. 61: 1648. DOI: 10.2337/Db12-Er06A  0.483
2012 Xia C, Chernatynskaya A, Wasserfall C, Looney B, Wan S, Clare-Salzler M, Atkinson M. Anti-Thymocyte Globulin (ATG) Differentially Depletes naïve and Memory T Cells and Permits Memory-Type Regulatory T Cells Blood. 120: 4670-4670. DOI: 10.1182/Blood.V120.21.4670.4670  0.326
2011 Gagliani N, Gregori S, Jofra T, Valle A, Stabilini A, Rothstein DM, Atkinson M, Roncarolo MG, Battaglia M. Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation. Plos One. 6: e28434. PMID 22174806 DOI: 10.1371/Journal.Pone.0028434  0.323
2011 Schatz DA, Levine SR, Atkinson MA. It's time to mow the GRAS in type 1 diabetes. Diabetes. 60: 2669-71. PMID 22025772 DOI: 10.2337/Db11-1158  0.309
2011 Serreze DV, Chapman HD, Niens M, Dunn R, Kehry MR, Driver JP, Haller M, Wasserfall C, Atkinson MA. Loss of intra-islet CD20 expression may complicate efficacy of B-cell-directed type 1 diabetes therapies. Diabetes. 60: 2914-21. PMID 21926271 DOI: 10.2337/Db11-0705  0.376
2011 Blanton D, Han Z, Bierschenk L, Linga-Reddy MV, Wang H, Clare-Salzler M, Haller M, Schatz D, Myhr C, She JX, Wasserfall C, Atkinson M. Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes. Diabetes. 60: 2566-70. PMID 21844098 DOI: 10.2337/Db11-0576  0.394
2011 Wasserfall C, Nead K, Mathews C, Atkinson MA. The threshold hypothesis: Solving the equation of nurture vs nature in type 1 diabetes Diabetologia. 54: 2232-2236. PMID 21773685 DOI: 10.1007/S00125-011-2244-Z  0.315
2011 Ize-Ludlow D, Lightfoot YL, Parker M, Xue S, Wasserfall C, Haller MJ, Schatz D, Becker DJ, Atkinson MA, Mathews CE. Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes. Diabetes. 60: 2086-91. PMID 21659497 DOI: 10.2337/Db11-0373  0.404
2011 Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 60: 1370-9. PMID 21525508 DOI: 10.2337/Db10-1797  0.314
2011 Greenbaum C, Atkinson MA. Persistence is the twin sister of excellence: an important lesson for attempts to prevent and reverse type 1 diabetes. Diabetes. 60: 693-4. PMID 21357468 DOI: 10.2337/Db10-1810  0.321
2011 Lau K, Benitez P, Ardissone A, Wilson TD, Collins EL, Lorca G, Li N, Sankar D, Wasserfall C, Neu J, Atkinson MA, Shatz D, Triplett EW, Larkin J. Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias. Journal of Immunology (Baltimore, Md. : 1950). 186: 3538-46. PMID 21317395 DOI: 10.4049/Jimmunol.1001864  0.324
2011 Racine J, Wang M, Zhang C, Lin CL, Liu H, Todorov I, Atkinson M, Zeng D. Induction of mixed chimerism with MHC-mismatched but not matched bone marrow transplants results in thymic deletion of host-type autoreactive T-cells in NOD mice. Diabetes. 60: 555-64. PMID 21270266 DOI: 10.2337/Db10-0827  0.387
2011 El Haddad N, Heathcote D, Moore R, Yang S, Azzi J, Mfarrej B, Atkinson M, Sayegh MH, Lee JS, Ashton-Rickardt PG, Abdi R. Mesenchymal stem cells express serine protease inhibitor to evade the host immune response Blood. 117: 1176-1183. PMID 21076046 DOI: 10.1182/Blood-2010-06-287979  0.319
2011 Giongo A, Gano KA, Crabb DB, Mukherjee N, Novelo LL, Casella G, Drew JC, Ilonen J, Knip M, Hyöty H, Veijola R, Simell T, Simell O, Neu J, Wasserfall CH, ... ... Atkinson MA, et al. Toward defining the autoimmune microbiome for type 1 diabetes. The Isme Journal. 5: 82-91. PMID 20613793 DOI: 10.1038/Ismej.2010.92  0.331
2011 Rowe PA, Campbell-Thompson ML, Schatz DA, Atkinson MA. The pancreas in human type 1 diabetes. Seminars in Immunopathology. 33: 29-43. PMID 20495921 DOI: 10.1007/S00281-010-0208-X  0.304
2011 Atkinson MA. Response to comment on: Atkinson. It's time to consider changing the rules: The rationale for rethinking control groups in clinical trials aimed at reversing type 1 diabetes. Diabetes 2011;60:361-363 Diabetes. 60. DOI: 10.2337/Db11-0365  0.326
2011 Giongo A, Atkinson MA, Triplett EW. Microbiology of Type 1 diabetes: possible implications for management of the disease Diabetes Management. 1: 325-331. DOI: 10.2217/Dmt.11.24  0.385
2010 Brophy S, Davies H, Stephens JW, Prior SL, Atkinson M, Bain S, Williams R. Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study. Bmc Research Notes. 3: 317. PMID 21092154 DOI: 10.1186/1756-0500-3-317  0.303
2010 Jurewicz M, Yang S, Augello A, Godwin JG, Moore RF, Azzi J, Fiorina P, Atkinson M, Sayegh MH, Abdi R. Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes. Diabetes. 59: 3139-47. PMID 20841611 DOI: 10.2337/Db10-0542  0.448
2010 Vergani A, D'Addio F, Jurewicz M, Petrelli A, Watanabe T, Liu K, Law K, Schuetz C, Carvello M, Orsenigo E, Deng S, Rodig SJ, Ansari JM, Staudacher C, Abdi R, ... ... Atkinson M, et al. A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice. Diabetes. 59: 2253-64. PMID 20805386 DOI: 10.2337/Db09-1264  0.4
2010 Schatz DA, Haller MJ, Atkinson MA. Type I diabetes. Preface. Endocrinology and Metabolism Clinics of North America. 39: xvii-xviii. PMID 20723814 DOI: 10.1016/J.Ecl.2010.05.012  0.369
2010 Li N, Hatch M, Wasserfall CH, Douglas-Escobar M, Atkinson MA, Schatz DA, Neu J. Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak? Journal of Pediatric Gastroenterology and Nutrition. 51: 414-7. PMID 20706153 DOI: 10.1097/Mpg.0B013E3181Dd913A  0.364
2010 Tao B, Pietropaolo M, Atkinson M, Schatz D, Taylor D. Estimating the Cost of Type 1 Diabetes in the U.S.: A Propensity Score Matching Method Plos One. 5. PMID 20634976 DOI: 10.1371/Journal.Pone.0011501  0.427
2010 Ma H, Lu Y, Li H, Campbell-Thompson M, Parker M, Wasserfall C, Haller M, Brantly M, Schatz D, Atkinson M, Song S. Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease. Diabetologia. 53: 2198-204. PMID 20593162 DOI: 10.1007/S00125-010-1829-2  0.476
2010 Nierras CR, Atkinson MA, Goldstein RA. The juvenile diabetes research foundation at forty: Updates of research in type 1 diabetes Diabetes. 59: 1575-1577. PMID 20587801 DOI: 10.2337/Db10-0622  0.333
2010 Zhang C, Wang M, Racine JJ, Liu H, Lin CL, Nair I, Lau J, Cao YA, Todorov I, Atkinson M, Zeng D. Induction of chimerism permits low-dose islet grafts in the liver or pancreas to reverse refractory autoimmune diabetes. Diabetes. 59: 2228-36. PMID 20530743 DOI: 10.2337/Db10-0450  0.462
2010 Shoda L, Kreuwel H, Gadkar K, Zheng Y, Whiting C, Atkinson M, Bluestone J, Mathis D, Young D, Ramanujan S. The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse. Clinical and Experimental Immunology. 161: 250-67. PMID 20491795 DOI: 10.1111/J.1365-2249.2010.04166.X  0.494
2010 Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, Gonzalez CF, Wasserfall CH, Larkin J, Schatz D, Atkinson MA, Triplett EW, Neu J, Lorca GL. Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. Plos One. 5: e10507. PMID 20463897 DOI: 10.1371/Journal.Pone.0010507  0.348
2010 Gianani R, Campbell-Thompson M, Sarkar SA, Wasserfall C, Pugliese A, Solis JM, Kent SC, Hering BJ, West E, Steck A, Bonner-Weir S, Atkinson MA, Coppieters K, von Herrath M, Eisenbarth GS. Dimorphic histopathology of long-standing childhood-onset diabetes. Diabetologia. 53: 690-8. PMID 20062967 DOI: 10.1007/S00125-009-1642-Y  0.382
2010 Gagliani N, Jofra T, Stabilini A, Valle A, Atkinson M, Roncarolo MG, Battaglia M. Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant. Diabetes. 59: 433-439. PMID 19934002 DOI: 10.2337/Db09-1168  0.364
2010 Xue S, Wasserfall C, Parker M, McGrail S, McGrail K, Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ. Exendin-4 treatment of nonobese diabetic mice increases beta-cell proliferation and fractional insulin reactive area. Journal of Diabetes and Its Complications. 24: 163-7. PMID 19217320 DOI: 10.1016/J.Jdiacomp.2008.12.004  0.399
2009 Bierschenk L, Alexander J, Wasserfall C, Haller M, Schatz D, Atkinson M. Vitamin D levels in subjects with and without type 1 diabetes residing in a solar rich environment. Diabetes Care. 32: 1977-9. PMID 19675194 DOI: 10.2337/Dc09-1089  0.392
2009 Haller MJ, Atkinson MA, Schatz DA. The road not taken: a path to curing type 1 diabetes? European Journal of Immunology. 39: 2054-8. PMID 19672902 DOI: 10.1002/Eji.200939517  0.357
2009 Yip L, Su L, Sheng D, Chang P, Atkinson M, Czesak M, Albert PR, Collier AR, Turley SJ, Fathman CG, Creusot RJ. Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Nature Immunology. 10: 1026-33. PMID 19668219 DOI: 10.1038/Ni.1773  0.433
2009 Parker MJ, Xue S, Alexander JJ, Wasserfall CH, Campbell-Thompson ML, Battaglia M, Gregori S, Mathews CE, Song S, Troutt M, Eisenbeis S, Williams J, Schatz DA, Haller MJ, Atkinson MA. Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice. Diabetes. 58: 2277-84. PMID 19628781 DOI: 10.2337/Db09-0557  0.404
2009 Fiorina P, Jurewicz M, Augello A, Vergani A, Dada S, La Rosa S, Selig M, Godwin J, Law K, Placidi C, Smith RN, Capella C, Rodig S, Adra CN, Atkinson M, et al. Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 183: 993-1004. PMID 19561093 DOI: 10.4049/Jimmunol.0900803  0.372
2009 Atkinson MA, Gianani R. The pancreas in human type 1 diabetes: providing new answers to age-old questions. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 279-85. PMID 19502978 DOI: 10.1097/Med.0B013E32832E06Ba  0.355
2009 Huang Y, Parker M, Xia C, Peng R, Wasserfall C, Clarke T, Wu L, Chowdhry T, Campbell-Thompson M, Williams J, Clare-Salzler M, Atkinson MA, Womer KL. Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic cell profile and function in NOD mice to suppress diabetogenic responses. Journal of Immunology (Baltimore, Md. : 1950). 182: 4608-15. PMID 19342635 DOI: 10.4049/Jimmunol.0713269  0.314
2009 Roesch LF, Lorca GL, Casella G, Giongo A, Naranjo A, Pionzio AM, Li N, Mai V, Wasserfall CH, Schatz D, Atkinson MA, Neu J, Triplett EW. Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model. The Isme Journal. 3: 536-48. PMID 19225551 DOI: 10.1038/Ismej.2009.5  0.31
2009 Valle A, Jofra T, Stabilini A, Atkinson M, Roncarolo MG, Battaglia M. Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice Diabetes. 58: 875-881. PMID 19151201 DOI: 10.2337/Db08-1432  0.432
2009 Wasserfall C, Atkinson MA. Taking a daily vitamin to prevent type 1 diabetes? Diabetes. 58: 24-5. PMID 19114727 DOI: 10.2337/Db08-1479  0.353
2009 Parker M, Xue S, Wasserfall C, Campbell-Thompson M, Atkinson M. T.8. Amelioration of Insulitis and Reversal of Diabetes in NOD Mice by Murine Anti-Thymocyte Globulin and Granulocyte-Colony Stimulating Factor Combination Therapy Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.137  0.411
2008 Xue S, Wasserfall CH, Parker M, Brusko TM, McGrail S, McGrail K, Moore M, Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ. Exendin-4 therapy in NOD mice with new-onset diabetes increases regulatory T cell frequency. Annals of the New York Academy of Sciences. 1150: 152-6. PMID 19120286 DOI: 10.1196/Annals.1447.049  0.313
2008 Sanjeevi CB, Schatz DA, Atkinson MA. The IDS conducts standardization of assays for the measurement of autoantibodies and of T cells in autoimmune diabetes. Preface. Annals of the New York Academy of Sciences. 1150: xiii. PMID 19120260 DOI: 10.1196/Annals.1447.066  0.334
2008 Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, Rabinovitch A. Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice Diabetes. 57: 3281-3288. PMID 18835930 DOI: 10.2337/Db08-0688  0.446
2008 Vaarala O, Atkinson MA, Neu J. The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes. 57: 2555-62. PMID 18820210 DOI: 10.2337/Db08-0331  0.361
2008 Lu Y, Parker M, Pileggi A, Zhang B, Choi Y-, Molano RD, Wasserfall C, Ricordi C, Inverardi L, Brantly M, Schatz D, Atkinson M, Song S. Human alpha 1‐antitrypsin therapy induces fatal anaphylaxis in non‐obese diabetic mice Clinical and Experimental Immunology. 154: 15-21. PMID 18759852 DOI: 10.1111/J.1365-2249.2008.03721.X  0.379
2008 Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T. The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 949-61. PMID 18607348 DOI: 10.1038/Labinvest.2008.60  0.305
2008 Abdi R, Fiorina P, Adra CN, Atkinson M, Sayegh MH. Immunomodulation by Mesenchymal Stem Cells A Potential Therapeutic Strategy for Type 1 Diabetes Diabetes. 57: 1759-1767. PMID 18586907 DOI: 10.2337/Db08-0180  0.369
2008 Pileggi A, Molano RD, Song S, Zahr E, SanJose S, Villate S, Wasserfall C, Ricordi C, Atkinson MA, Inverardi L. Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts. Transplantation Proceedings. 40: 457-8. PMID 18374100 DOI: 10.1016/j.transproceed.2008.02.010  0.304
2008 Koya V, Lu S, Sun YP, Purich DL, Atkinson MA, Li SW, Yang LJ. Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy. Diabetes. 57: 757-69. PMID 18086901 DOI: 10.2337/Db07-1441  0.338
2008 Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M, Eisenbeis S, Williams J, ... ... Atkinson MA, et al. Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time-dependent induction of immunoregulation. Diabetes. 57: 405-14. PMID 18039815 DOI: 10.2337/Db06-1384  0.313
2008 Nayak S, Hoffman B, Cooper M, Atkinson M, Cao O, Herzog RW. A Prophylactic Protocol for the Prevention of Inhibitor Formation in Gene Therapy for Hemophilia B by Shifting the Balance from An Effector to a Regulatory T Cell Response Blood. 112: 3531-3531. DOI: 10.1182/Blood.V112.11.3531.3531  0.335
2007 Brusko T, Atkinson M. Treg in type 1 diabetes. Cell Biochemistry and Biophysics. 48: 165-75. PMID 17709886 DOI: 10.1007/S12013-007-0018-5  0.492
2007 Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, Bailey R, Bourget K, Plagnol V, Field S, Atkinson M, Clayton DG, Wicker LS, Todd JA. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nature Genetics. 39: 1074-82. PMID 17676041 DOI: 10.1038/Ng2102  0.351
2007 Guleria I, Gubbels Bupp M, Dada S, Fife B, Tang Q, Ansari MJ, Trikudanathan S, Vadivel N, Fiorina P, Yagita H, Azuma M, Atkinson M, Bluestone JA, Sayegh MH. Mechanisms of PDL1-mediated regulation of autoimmune diabetes. Clinical Immunology (Orlando, Fla.). 125: 16-25. PMID 17627890 DOI: 10.1016/J.Clim.2007.05.013  0.408
2007 Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, Swan R, Chung CS, Atkinson MA, Ramphal R, Gabrilovich DI, et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. The Journal of Experimental Medicine. 204: 1463-74. PMID 17548519 DOI: 10.1084/Jem.20062602  0.321
2007 Zheng Y, Kreuwel HT, Young DL, Shoda LK, Ramanujan S, Gadkar KG, Atkinson MA, Whiting CC. The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes. Annals of the New York Academy of Sciences. 1103: 45-62. PMID 17376834 DOI: 10.1196/Annals.1394.014  0.419
2007 King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity Annals of the New York Academy of Sciences. 1103: 90-93. PMID 17376822 DOI: 10.1196/Annals.1394.011  0.313
2007 Zhang B, Lu Y, Campbell-Thompson M, Spencer T, Wasserfall C, Atkinson M, Song S. Alpha1-antitrypsin protects beta-cells from apoptosis. Diabetes. 56: 1316-23. PMID 17360983 DOI: 10.2337/Db06-1273  0.409
2007 Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, Haller M, Rockell J, Gottlieb P, Clare-Salzler M, Atkinson M. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes. 56: 604-12. PMID 17327427 DOI: 10.2337/Db06-1248  0.341
2007 Zhang C, Todorov I, Lin CL, Atkinson M, Kandeel F, Forman S, Zeng D. Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 2337-42. PMID 17267595 DOI: 10.1073/Pnas.0611101104  0.498
2007 Nakagawa T, Sato W, Glushakova O, Heinig M, Clarke T, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Johnson RJ, Croker B. Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 18: 539-50. PMID 17202420 DOI: 10.1681/Asn.2006050459  0.318
2007 Schwartz RF, Neu J, Schatz D, Atkinson MA, Wasserfall C. Comment on: Brugman S et al. (2006) Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia 49:2105-2108 [4] Diabetologia. 50: 220-221. PMID 17119915 DOI: 10.1007/S00125-006-0526-7  0.339
2007 Zhang C, Kandeel F, Todorov I, Atkinson M, Lin C, Forman S, Zeng D. Elimination of Insulitis and Augmentation of Islet β Cell Regeneration via Induction of Chimerism in Overtly Diabetic NOD Mice Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.474  0.447
2006 Wasserfall CH, Atkinson MA. Autoantibody markers for the diagnosis and prediction of type 1 diabetes Autoimmunity Reviews. 5: 424-428. PMID 16890898 DOI: 10.1016/J.Autrev.2005.12.002  0.404
2006 Lu Y, Tang M, Wasserfall C, Kou Z, Campbell-Thompson M, Gardemann T, Crawford J, Atkinson M, Song S. Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice. Human Gene Therapy. 17: 625-34. PMID 16776571 DOI: 10.1089/Hum.2006.17.625  0.495
2006 Chen S, Wasserfall C, Kapturczak MH, Atkinson M, Agarwal A. Freeze-thaw increases adeno-associated virus transduction of cells. American Journal of Physiology. Cell Physiology. 291: C386-92. PMID 16510845 DOI: 10.1152/Ajpcell.00582.2005  0.303
2006 Lee CH, Chen YG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M, Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH. Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis. Diabetes. 55: 171-8. PMID 16380490  0.39
2006 Bonifacio E, Atkinson M, Eisenbarth G, Serreze D, Kay TWH, Lee-Chan E, Singh B. International Workshop on Lessons from Animal Models for Human Type 1 Diabetes Annals of the New York Academy of Sciences. 958: 1-2. PMID 12021078 DOI: 10.1111/J.1749-6632.2002.Tb02941.X  0.455
2006 Song S, Lu Y, Tang M, Zhang B, Wasserfall C, Campbell-Thompson M, Atkinson M. 71. Alpha 1 Antitrypsin (AAT) Gene Therapy for the Prevention of Type 1 Diabetes Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.088  0.494
2006 Guleria I, Dada S, Eckenrode S, Bupp MG, Ansari M, Vadivel N, Trikudanathan S, Fiorina P, Khosroshahi A, Yagita H, Azuma M, Atkinson M, She J, Bluestone J, Sayegh M. Su.26. PDL1 Regulates Autoimmunity By Limiting Expansion of Autoreactive Th1 Cells and Mediates Resistance to Diabetes in Nod Mice Clinical Immunology. 119: S168. DOI: 10.1016/J.Clim.2006.04.453  0.437
2005 Fudge E, Carol J, She JX, Dosch M, Atkinson M, Muir A. Chronic inflammatory demyelinating polyradiculoneuropathy in two children with type 1 diabetes mellitus. Pediatric Diabetes. 6: 244-248. PMID 16390395 DOI: 10.1111/J.1399-543X.2005.00130.X  0.464
2005 Haller MJ, Atkinson MA, Schatz D. Type 1 diabetes mellitus: Etiology, presentation, and management Pediatric Clinics of North America. 52: 1553-1578. PMID 16301083 DOI: 10.1016/J.Pcl.2005.07.006  0.353
2005 Atkinson MA, Rhodes CJ. Pancreatic regeneration in type 1 diabetes: Dreams on a deserted islet? Diabetologia. 48: 2200-2202. PMID 16193285 DOI: 10.1007/S00125-005-1957-2  0.357
2005 Litherland SA, Grebe KM, Belkin NS, Paek E, Elf J, Atkinson M, Morel L, Clare-Salzler MJ, McDuffie M. Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction. Journal of Immunology (Baltimore, Md. : 1950). 175: 4561-5. PMID 16177100 DOI: 10.4049/Jimmunol.175.7.4561  0.412
2005 Lee CH, Reifsnyder PC, Naggert JK, Wasserfall C, Atkinson MA, Chen J, Leiter EH. Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis Diabetes. 54: 2525-2532. PMID 16123339 DOI: 10.2337/Diabetes.54.9.2525  0.329
2005 Neu J, Reverte CM, Mackey AD, Liboni K, Tuhacek-Tenace LM, Hatch M, Li N, Caicedo RA, Schatz DA, Atkinson M. Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes. Journal of Pediatric Gastroenterology and Nutrition. 40: 589-95. PMID 15861021 DOI: 10.1097/01.Mpg.0000159636.19346.C1  0.457
2005 Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4 +CD25+ T-cells in type 1 diabetes Diabetes. 54: 1407-1414. PMID 15855327 DOI: 10.2337/Diabetes.54.5.1407  0.308
2005 Atkinson MA. Thirty years of investigating the autoimmune basis for type 1 diabetes: Why can't we prevent or reverse this disease? Diabetes. 54: 1253-1263. PMID 15855308 DOI: 10.2337/Diabetes.54.5.1253  0.385
2005 Li M, Guo D, Isales CM, Eizirik DL, Atkinson M, She JX, Wang CY. SUMO wrestling with type 1 diabetes. Journal of Molecular Medicine (Berlin, Germany). 83: 504-13. PMID 15806321 DOI: 10.1007/S00109-005-0645-5  0.383
2005 Ramirez-Montealegre D, Chattopadhyay S, Curran TM, Wasserfall C, Pritchard L, Schatz D, Petitto J, Hopkins D, She JX, Rothberg PG, Atkinson M, Pearce DA. Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease. Neurology. 64: 743-5. PMID 15728308 DOI: 10.1212/01.Wnl.0000151973.08426.7E  0.398
2005 Cresawn KO, Fraites TJ, Wasserfall C, Atkinson M, Lewis M, Porvasnik S, Liu C, Mah C, Byrne BJ. Impact of humoral immune response on distribution and efficacy of recombinant adeno-associated virus-derived acid α-glucosidase in a model of glycogen storage disease type II Human Gene Therapy. 16: 68-80. PMID 15703490 DOI: 10.1089/Hum.2005.16.68  0.306
2005 Greenbaum CJ, Eisenbarth G, Atkinson M, Yu L, Babu S, Schatz D, Zeidler A, Orban T, Wasserfall C, Cuthbertson D, Krischer J. High frequency of abnormal glucose tolerance in DQA1*0102/ DQB1*0602 relatives identified as part of the Diabetes Prevention Trial - Type 1 Diabetes Diabetologia. 48: 68-74. PMID 15602651 DOI: 10.1007/S00125-004-1608-Z  0.469
2005 Liang Y, Huang T, Zhang C, Todorov I, Atkinson M, Kandeel F, Forman S, Zeng D. Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb. Blood. 105: 2180-8. PMID 15374883 DOI: 10.1182/Blood-2004-06-2411  0.355
2005 Morales A, Wasserfall C, Brusko T, Carter C, Schatz D, Silverstein J, Ellis T, Atkinson M. Adiponectin and leptin concentrations may aid in discriminating disease forms in children and adolescents with type 1 and type 2 diabetes. Diabetes Care. 27: 2010-4. PMID 15277432 DOI: 10.2337/Diacare.27.8.2010  0.46
2005 Lee C, Chen Y, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M, Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH. Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes Progression: II. Immunologic Analysis Diabetes. 55: 171-178. DOI: 10.2337/Diabetes.55.01.06.Db05-1129  0.379
2005 Caicedo RA, Li N, Atkinson MA, Schatz DA, Neu J. Neonatal Nutritional Interventions in the Prevention of Type 1 Diabetes Neoreviews. 6: e220-e226. DOI: 10.1542/Neo.6-5-E220  0.371
2004 Roep BO, Atkinson M, Herrath Mv. Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes Nature Reviews Immunology. 4: 989-997. PMID 15573133 DOI: 10.1038/Nri1502  0.449
2004 Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF, Atkinson M, Shuster JJ, Pierce GL, Silverstein JH. Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes Diabetes Care. 27: 2911-2917. PMID 15562206 DOI: 10.2337/Diacare.27.12.2911  0.385
2004 You S, Chen C, Lee WH, Brusko T, Atkinson M, Liu CP. Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 6777-85. PMID 15557171 DOI: 10.4049/Jimmunol.173.11.6777  0.399
2004 Roep BO, Atkinson M. Animal models have little to teach us about Type 1 diabetes: 1. In support of this proposal Diabetologia. 47: 1650-1656. PMID 15490110 DOI: 10.1007/S00125-004-1517-1  0.49
2004 Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, et al. A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nature Genetics. 36: 837-41. PMID 15247916 DOI: 10.1038/Ng1391  0.352
2004 Schatz D, Cuthbertson D, Atkinson M, Salzler MC, Winter W, Muir A, Silverstein J, Cook R, Maclaren N, She J, Greenbaum C, Krischer J. Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression? Pediatric Diabetes. 5: 72-79. PMID 15189492 DOI: 10.1111/J.1399-543X.2004.00047.X  0.442
2004 Gale EAM, Atkinson M. A piece of nucleic acid surrounded by controversy: coxsackievirus and the causes of Type 1 diabetes. Diabetic Medicine. 21: 503-506. PMID 15154931 DOI: 10.1111/J.1464-5491.2004.01181.X  0.439
2004 Zhang YC, Powers M, Wasserfall C, Brusko T, Song S, Flotte T, Snyder RO, Potter M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick HS, Agarwal A, Ellis TM, Atkinson MA. Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunity. Gene Therapy. 11: 233-40. PMID 14737082 DOI: 10.1038/Sj.Gt.3302144  0.306
2004 Song S, Goudy K, Campbell-Thompson M, Wasserfall C, Scott-Jorgensen M, Wang J, Tang Q, Crawford JM, Ellis TM, Atkinson MA, Flotte TR. Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice Gene Therapy. 11: 181-186. PMID 14712302 DOI: 10.1038/Sj.Gt.3302156  0.485
2004 Yu L, Eisenbarth G, Bonifacio E, Thomas J, Atkinson M, Wasserfall C. The second murine autoantibody workshop: remarkable interlaboratory concordance for radiobinding assays to identify insulin autoantibodies in nonobese diabetic mice. Annals of the New York Academy of Sciences. 1005: 1-12. PMID 14679035 DOI: 10.1196/Annals.1288.002  0.441
2004 Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, et al. Erratum: Corrigendum: A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes Nature Genetics. 36: 1024-1024. DOI: 10.1038/Ng0904-1024B  0.351
2004 Lu Y, Tang M, Wasserfall C, Choi Y, Gardmann T, Campbell-Thompson M, Atkinson MA, Song S. 429. Alpha 1 Antitrypsin Gene Delivery for Preventing Type 1 Diabetes in NOD Mice|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.384  0.37
2004 Loiler SA, Tang Q, Perret-Gentil M, Campbell-Thompson ML, Atkinson MA, Flotte TR. 169. Intrapancreatic injections of adeno-associated virus vectors for local gene expression Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.129  0.302
2003 Litherland SA, She JX, Schatz D, Fuller K, Hutson AD, Peng RH, Li Y, Grebe KM, Whittaker DS, Bahjat K, Hopkins D, Fang Q, Spies PD, North K, Wasserfall C, ... ... Atkinson M, et al. Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset. Pediatric Diabetes. 4: 10-8. PMID 14655518 DOI: 10.1034/J.1399-5448.2003.00042.X  0.472
2003 Schatz D, Gale EAM, Atkinson MA. Why Can't We Prevent Type I Diabetes?: Maybe it's time to try a different combination Diabetes Care. 26: 3326-3328. PMID 14633822 DOI: 10.2337/Diacare.26.12.3326  0.39
2003 Atkinson M, Gale EAM. Infant diets and type 1 diabetes: too early, too late, or just too complicated? Jama. 290: 1771-1772. PMID 14519713 DOI: 10.1001/Jama.290.13.1771  0.384
2003 Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA. Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion. Journal of Immunology (Baltimore, Md. : 1950). 171: 2270-8. PMID 12928371 DOI: 10.4049/Jimmunol.171.5.2270  0.355
2003 Qin HY, Mahon JL, Atkinson MA, Chaturvedi P, Lee-Chan E, Singh B. Type 1 diabetes alters anti-hsp90 autoantibody isotype Journal of Autoimmunity. 20: 237-245. PMID 12753809 DOI: 10.1016/S0896-8411(03)00035-0  0.368
2002 Atkinson MA, Wilson SB. Fatal attraction: chemokines and type 1 diabetes. The Journal of Clinical Investigation. 110: 1611-3. PMID 12464665 DOI: 10.1172/Jci17311  0.386
2002 Kapturczak M, Zolotukhin S, Cross J, Pileggi A, Molano RD, Jorgensen M, Byrne B, Flotte TR, Ellis T, Inverardi L, Ricordi C, Nick H, Atkinson M, Agarwal A. Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 154-60. PMID 11829522 DOI: 10.1006/Mthe.2002.0522  0.368
2001 Kapturczak MH, Flotte T, Atkinson MA. Adeno-Associated Virus (AAV) as a vehicle for therapeutic gene delivery: Improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet cell transplantation for the reversal of type 1 diabetes Current Molecular Medicine. 1: 245-258. PMID 11899074 DOI: 10.2174/1566524013363979  0.302
2001 Brod SA, Atkinson M, Lavis VR, Brosnan PG, Hardin DS, Orlander PR, Nguyen M, Riley WJ. Ingested IFN-α preserves residual β cell function in type 1 diabetes Journal of Interferon and Cytokine Research. 21: 1021-1030. PMID 11798459 DOI: 10.1089/107999001317205141  0.446
2001 Goudy K, Song S, Wasserfall C, Zhang YC, Kapturczak M, Muir A, Powers M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Ellis TM, Flotte TR, Atkinson MA. Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice Proceedings of the National Academy of Sciences of the United States of America. 98: 13913-13918. PMID 11717448 DOI: 10.1073/pnas.251532298  0.353
2001 Bonifacio E, Atkinson M, Eisenbarth G, Serreze D, Kay TWH, Lee-Chan E, Singh B. International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice. Diabetes. 50: 2451-2458. PMID 11679421 DOI: 10.2337/Diabetes.50.11.2451  0.44
2001 Atkinson MA, Eisenbarth GS. Type 1 diabetes: New perspectives on disease pathogenesis and treatment Lancet. 358: 221-229. PMID 11476858 DOI: 10.1016/S0140-6736(01)05415-0  0.357
2001 Tisch R, Wang B, Atkinson MA, Serreze DV, Friedline R. A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice Journal of Immunology. 166: 6925-6936. PMID 11359854 DOI: 10.4049/Jimmunol.166.11.6925  0.32
2001 Flotte T, Agarwal A, Wang J, Song S, Fenjves ES, Inverardi L, Chesnut K, Afione S, Loiler S, Wasserfall C, Kapturczak M, Ellis T, Nick H, Atkinson M. Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors. Diabetes. 50: 515-20. PMID 11246870 DOI: 10.2337/Diabetes.50.3.515  0.368
2001 Haskins K, Atkinson M. Prediction of diabetes and response to therapy in individual animals: Are there lessons for man? Report on the JDF/Snow Mountain meeting, 5-7 October 2000, Winter Park, CO, USA Journal of Autoimmunity. 16: 15-19. PMID 11221992 DOI: 10.1006/Jaut.2000.0467  0.388
2001 Bingley PJ, Bonifacio E, Ziegler AG, Schatz DA, Atkinson MA, Eisenbarth GS. Proposed guidelines on screening for risk of type 1 diabetes Diabetes Care. 24: 398. PMID 11213898 DOI: 10.2337/Diacare.24.2.398  0.393
2000 Atkinson M, Honeyman M, Peakman M, Roep B. T-cell markers in type I diabetes: progress, prospects and realistic expectations. Diabetologia. 43: 819-820. PMID 10907132 DOI: 10.1007/S001250070001  0.465
2000 Serreze DV, Ottendorfer EW, Elliss TM, Gauntt CJ, Atkinson MA. Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets Diabetes. 49: 708-711. PMID 10905477 DOI: 10.2337/Diabetes.49.5.708  0.351
2000 Atkinson MA. The $64,000 question in diabetes continues . . Lancet. 355: 4-6. PMID 10892753 DOI: 10.1016/S0140-6736(00)02421-1  0.355
2000 Atkinson M, Ellis T, Serreze D. Control of Autoimmune Diabetes Science. 287: 191-191. DOI: 10.1126/Science.287.5451.191A  0.369
1999 Ottendorfer E, Ellis TM, Bahjat KS, Clare-Salzler M, Atkinson MA. No alteration in T lymphocyte expression of CD40 ligand (CD154) in individuals with or at increased risk for insulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 84: 4068-4072. PMID 10566651 DOI: 10.1210/Jcem.84.11.6107  0.314
1999 Roep BO, Atkinson MA, van Endert PM, Gottlieb PA, Wilson SB, Sachs JA. Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays. Journal of Autoimmunity. 13: 267-82. PMID 10479395 DOI: 10.1006/Jaut.1999.0312  0.373
1999 She JX, Ellis TM, Wilson SB, Wasserfall CH, Marron M, Reimsneider S, Kent SC, Hafler DA, Neuberg DS, Muir A, Strominger JL, Atkinson MA. Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 96: 8116-9. PMID 10393957 DOI: 10.1073/pnas.96.14.8116  0.323
1999 Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: As good as it gets? Nature Medicine. 5: 601-604. PMID 10371488 DOI: 10.1038/9442  0.356
1999 Leslie RD, Atkinson MA, Notkins AL. Autoantigens IA-2 and GAD in Type I (insulin-dependent) diabetes. Diabetologia. 42: 3-14. PMID 10027571 DOI: 10.1007/S001250051105  0.349
1999 Wilson SB, Kent SC, Patton KT, Orban T, Jackson RA, Exley M, Porcelli S, Schatz DA, Atkinson MA, Balk SP, Strominger JL, Hafler DA. Erratum: Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes Nature. 399: 84-84. DOI: 10.1038/20007  0.364
1998 Ellis TM, Ottendorfer E, Jodoin E, Salisbury PJ, She JX, Schatz DA, Atkinson MA. Cellular immune responses to β casein: Elevated in but not specific for individuals with Type I diabetes mellitus Diabetologia. 41: 731-735. PMID 9662058 DOI: 10.1007/S001250050976  0.352
1998 Zechel MA, Elliott JF, Atkinson MA, Singh B. Characterization of novel T-cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice Journal of Autoimmunity. 11: 83-95. PMID 9480726 DOI: 10.1006/Jaut.1997.0178  0.328
1998 Wilson SB, Kent SC, Patton KT, Orban T, Jackson RA, Exley M, Porcelli S, Schatz DA, Atkinson MA, Balk SP, Strominger JL, Hafler DA. Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature. 391: 177-81. PMID 9428763 DOI: 10.1038/34419  0.403
1997 Atkinson MA. Molecular mimicry and the pathogenesis of insulin-dependent diabetes mellitus: Still just an attractive hypothesis Annals of Medicine. 29: 393-399. PMID 9453286 DOI: 10.3109/07853899708999368  0.32
1997 Cetkovic-Cvrlje M, Gerling IC, Muir A, Atkinson MA, Elliott JF, Leiter EH. Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate β-cell antigens Diabetes. 46: 1975-1982. PMID 9392483 DOI: 10.2337/Diab.46.12.1975  0.322
1996 Tian J, Clare-Salzler M, Herschenfeld A, Middleton B, Newman D, Mueller R, Arita S, Evans C, Atkinson MA, Mullen Y, Sarvetnick N, Tobin AJ, Lehmann PV, Kaufman DL. Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nature Medicine. 2: 1348-53. PMID 8946834 DOI: 10.1038/Nm1296-1348  0.323
1996 Aanstoot HJ, Kang SM, Kim J, Lindsay LA, Roll U, Knip M, Atkinson M, Mose-Larsen P, Fey S, Ludvigsson J, Landin L, Bruining J, Maclaren N, Akerblom HK, Baekkeskov S. Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes. Journal of Clinical Investigation. 97: 2772-2783. PMID 8675688 DOI: 10.1172/Jci118732  0.466
1994 Atkinson MA, Maclaren NK. Mechanisms of disease: The pathogenesis of insulin-dependent diabetes mellitus New England Journal of Medicine. 331: 1428-1436. PMID 7969282 DOI: 10.1056/Nejm199411243312107  0.302
1994 Schoot M, Schatz D, Atkinson M, Krischer J, Mehta H, Vold B, Maclaren N. GAD65 Autoantibodies Increase the Predictability but not the Sensitivity of Islet Cell and Insulin Autoantibodies for Developing Insulin Dependent Diabetes Mellitus Journal of Autoimmunity. 7: 865-872. PMID 7888042 DOI: 10.1006/Jaut.1994.1070  0.418
1994 Gerling IC, Atkinson MA, Leiter EH. The thymus as a site for evaluating the potency of candidate β cell autoantigens in NOD mice Journal of Autoimmunity. 7: 851-858. PMID 7888041 DOI: 10.1006/Jaut.1994.1068  0.379
1994 Harrison LC, Honeyman MC, Deaizpurua HJ, Schmidli RS, Colman PG, Tait BD, Cram DS, Atkinson M, Leslie DRG. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Journal of Endocrinological Investigation. 17: 581-584. PMID 7829833 DOI: 10.1007/Bf03347753  0.4
1993 Atkinson MA, Kaufman DL, Newman D, Tobin AJ, Maclaren NK. Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes. The Journal of Clinical Investigation. 91: 350-6. PMID 8423231 DOI: 10.1172/Jci116192  0.327
1993 Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature. 366: 69-72. PMID 7694152 DOI: 10.1038/366069A0  0.315
1992 Maclaren N, Atkinson M. Is Insulin-Dependent Diabetes Mellitus Environmentally Induced? The New England Journal of Medicine. 327: 348-349. PMID 1620174 DOI: 10.1056/Nejm199207303270509  0.446
1992 Kaufman DL, Erlander MG, Clare-Salzler M, Atkinson MA, Maclaren NK, Tobin AJ. Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. The Journal of Clinical Investigation. 89: 283-92. PMID 1370298 DOI: 10.1172/Jci115573  0.341
1992 Atkinson MA, Kaufman DL, Campbell L, Gibbs KA, Shah SC, Bu DF, Erlander MG, Tobin AJ, Maclaren NK. Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes. Lancet. 339: 458-9. PMID 1346821 DOI: 10.1016/0140-6736(92)91061-C  0.381
1990 Atkinson MA, Maclaren NK. What causes diabetes? Scientific American. 263: 62-71. PMID 2197720 DOI: 10.1038/Scientificamerican0790-62  0.346
1990 Riley WJ, Atkinson MA, Schatz DA, Maclaren NK. Comparison of islet autoantibodies in 'pre-diabetes' and recommendations for screening Journal of Autoimmunity. 3: 47-51. PMID 2187460 DOI: 10.1016/S0896-8411(09)90009-9  0.305
1990 Sathyamoorthy V, Atkinson MA, Bowers B, Korn ED. Functional consequences of the proteolytic removal of regulatory serines from the nonhelical tailpiece of Acanthamoeba myosin II. Biochemistry. 29: 3793-7. PMID 2160267 DOI: 10.1021/Bi00467A028  0.491
1990 Atkinson MA, Maclaren NK, Riley WJ, Sharp DW, Lacey PE. 64 000 Mr autoantibodies as predictors of insulin-dependent diabetes The Lancet. 335: 1357-1360. PMID 1971659 DOI: 10.1016/0140-6736(90)91241-2  0.338
1988 Riley WJ, Atkinson MA, MacLaren NK. Insulin autoantibodies in pre-diabetes Advances in Experimental Medicine and Biology. 246: 45-51. PMID 3074667 DOI: 10.1007/978-1-4684-5616-5_6  0.376
1988 Atkinson MA, Maclaren NK. Autoantibodies in nonobese diabetic mice immunoprecipitate 64,000-M(r) islet antigen Diabetes. 37: 1587-1590. PMID 3053305 DOI: 10.2337/Diab.37.11.1587  0.374
1988 Maclaren N, Riley W, Skordis N, Atkinson M, Spillar R, Silverstein J, Klein R, Vadheim C, Rotter J. Inherited susceptibility to insulin-dependent diabetes is associated with HLA-DR1, while DR5 is protective. Autoimmunity. 1: 197-205. PMID 2979618 DOI: 10.3109/08916938808997164  0.313
1988 Atkinson MA, Appella E, Corigliano-Murphy MA, Korn ED. Enzymatic activity and filament assembly of Acanthamoeba myosin II are regulated by adjacent domains at the end of the tail. Febs Letters. 234: 435-8. PMID 2968922 DOI: 10.1016/0014-5793(88)80132-7  0.503
Show low-probability matches.