Shanta Dhar - Publications

Affiliations: 
2010-2016 University of Georgia, Athens, Athens, GA 
 2016- University of Miami Miller School of Medicine, Miami, FL, United States 
Area:
Nanomedicine, Bio-inorganic materials
Website:
http://www.shantadharlab.com/index.php/shanta

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Surnar B, Kamran MZ, Shah AS, Basu U, Kolishetti N, Deo S, Jayaweera DT, Daunert S, Dhar S. Orally Administrable Therapeutic Synthetic Nanoparticle for Zika Virus. Acs Nano. PMID 31603314 DOI: 10.1021/acsnano.9b02807  0.72
2019 Velichkovska M, Surnar B, Nair M, Dhar S, Toborek M. Targeted Mitochondrial COQ Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells. Molecular Pharmaceutics. 16: 724-736. PMID 30592424 DOI: 10.1021/acs.molpharmaceut.8b01014  0.64
2018 Surnar B, Basu U, Banik B, Ahmad A, Marples B, Kolishetti N, Dhar S. Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530697 DOI: 10.1073/pnas.1816429115  1
2018 Pathak RK, Basu U, Ahmad A, Sarkar S, Kumar A, Surnar B, Ansari S, Wilczek K, Ivan ME, Marples B, Kolishetti N, Dhar S. A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation. Biomaterials. 187: 117-129. PMID 30336364 DOI: 10.1016/j.biomaterials.2018.08.062  1
2018 Surnar B, Kolishetti N, Basu U, Ahmad A, Goka E, Marples B, Kolb D, Lippman M, Dhar S. Reduction of cisplatin induced ototoxicity without compromising its antitumor activity. Biochemistry. PMID 30281285 DOI: 10.1021/acs.biochem.8b00712  0.72
2017 Banik B, Wen R, Marrache S, Kumar A, Kolishetti N, Howerth EW, Dhar S. Core hydrophobicity tuning of a self-assembled particle results in efficient lipid reduction and favorable organ distribution. Nanoscale. PMID 29218349 DOI: 10.1039/c7nr06295h  1
2017 Banik B, Dhar S. Centrifugation-Free Magnetic Isolation of Functional Mitochondria Using Paramagnetic Iron Oxide Nanoparticles. Current Protocols in Cell Biology. 76: 25.4.1-25.4.20. PMID 28862341 DOI: 10.1002/cpcb.26  1
2017 Marples B, Dhar S. Radiobiology and the Renewed Potential for Nanoparticles. International Journal of Radiation Oncology, Biology, Physics. 98: 489-491. PMID 28581384 DOI: 10.1016/j.ijrobp.2017.03.015  0.6
2017 Pathak RK, Wen R, Kolishetti N, Dhar S. A Prodrug of Two Approved Drugs, Cisplatin and Chlorambucil, for Chemo War Against Cancer. Molecular Cancer Therapeutics. PMID 28148716 DOI: 10.1158/1535-7163.MCT-16-0445  1
2016 Wen R, Dhar S. Turn up the cellular power generator with vitamin E analogue formulation. Chemical Science. 7: 5559-5567. PMID 30034696 DOI: 10.1039/c6sc00481d  0.68
2016 Banik B, Askins BW, Dhar S. Mito-magneto: a tool for nanoparticle mediated mitochondria isolation. Nanoscale. PMID 27735003 DOI: 10.1039/c6nr05882e  1
2016 Basu U, Banik B, Wen R, Pathak RK, Dhar S. The Platin-X series: activation, targeting, and delivery. Dalton Transactions (Cambridge, England : 2003). PMID 27493131 DOI: 10.1039/c6dt01738j  1
2016 Wen R, Umeano AC, Francis L, Sharma N, Tundup S, Dhar S. Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems. Vaccines. 4. PMID 27258316 DOI: 10.3390/vaccines4020018  0.68
2016 Chaudhary AK, Bhat TA, Kumar S, Kumar A, Kumar R, Underwood W, Koochekpour S, Shourideh M, Yadav N, Dhar S, Chandra D. Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African-American men with prostate cancer. British Journal of Cancer. PMID 27115471 DOI: 10.1038/bjc.2016.88  1
2016 Pathak RK, Dhar S. Unique Use of Alkylation for Chemo-Redox Activity by a Pt(IV) Prodrug. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 3029-36. PMID 26807548 DOI: 10.1002/chem.201503866  1
2016 Wen R, Banik B, Pathak RK, Kumar A, Kolishetti N, Dhar S. Nanotechnology inspired tools for mitochondrial dysfunction related diseases. Advanced Drug Delivery Reviews. PMID 26776231 DOI: 10.1016/j.addr.2015.12.024  1
2015 Kalathil AA, Kumar A, Banik B, Ruiter TA, Pathak RK, Dhar S. New formulation of old aspirin for better delivery. Chemical Communications (Cambridge, England). PMID 26503669 DOI: 10.1039/c5cc07316b  1
2015 Feldhaeusser B, Platt SR, Marrache S, Kolishetti N, Pathak RK, Montgomery DJ, Reno LR, Howerth E, Dhar S. Evaluation of nanoparticle delivered cisplatin in beagles. Nanoscale. 7: 13822-30. PMID 26234400 DOI: 10.1039/c5nr03447g  1
2015 Pathak RK, Dhar S. A Nanoparticle Cocktail: Temporal Release of Predefined Drug Combinations. Journal of the American Chemical Society. PMID 26086212 DOI: 10.1021/jacs.5b03078  1
2015 Marrache S, Dhar S. The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate. Chemical Science (Royal Society of Chemistry : 2010). 6: 1832-1845. PMID 25709804 DOI: 10.1039/C4SC01963F  1
2015 Marrache S, Tundup S, Harn DA, Dhar S. Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells. Methods in Molecular Biology (Clifton, N.J.). 1265: 113-22. PMID 25634271 DOI: 10.1007/978-1-4939-2288-8_9  1
2015 Marrache S, Pathak RK, Dhar S. Formulation and optimization of mitochondria-targeted polymeric nanoparticles. Methods in Molecular Biology (Clifton, N.J.). 1265: 103-12. PMID 25634270 DOI: 10.1007/978-1-4939-2288-8_8  1
2015 Hung SW, Marrache S, Cummins S, Bhutia YD, Mody H, Hooks SB, Dhar S, Govindarajan R. Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach. Cancer Letters. 359: 233-40. PMID 25600708 DOI: 10.1016/j.canlet.2015.01.017  1
2015 Pathak RK, Kolishetti N, Dhar S. Targeted nanoparticles in mitochondrial medicine. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 7: 315-29. PMID 25348382 DOI: 10.1002/wnan.1305  1
2014 Marrache S, Pathak RK, Dhar S. Detouring of cisplatin to access mitochondrial genome for overcoming resistance. Proceedings of the National Academy of Sciences of the United States of America. 111: 10444-9. PMID 25002500 DOI: 10.1073/pnas.1405244111  1
2014 Pathak RK, McNitt CD, Popik VV, Dhar S. Copper-free click-chemistry platform to functionalize cisplatin prodrugs. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 6861-5. PMID 24756923 DOI: 10.1002/chem.201402573  1
2014 Pathak RK, Marrache S, Harn DA, Dhar S. Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate. Acs Chemical Biology. 9: 1178-87. PMID 24617941 DOI: 10.1021/cb400944y  1
2014 Pathak RK, Marrache S, Choi JH, Berding TB, Dhar S. The prodrug platin-A: simultaneous release of cisplatin and aspirin. Angewandte Chemie (International Ed. in English). 53: 1963-7. PMID 24453035 DOI: 10.1002/anie.201308899  1
2013 Marrache S, Dhar S. Reply to Cormode et al.: High-density lipoprotein mimicking synthetic nanoparticle Proceedings of the National Academy of Sciences of the United States of America. 110. PMID 24171202 DOI: 10.1073/pnas.1311060110  1
2013 Hung SW, Mody H, Marrache S, Bhutia YD, Davis F, Cho JH, Zastre J, Dhar S, Chu CK, Govindarajan R. Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies. Plos One. 8: e71196. PMID 23940717 DOI: 10.1371/journal.pone.0071196  1
2013 Marrache S, Tundup S, Harn DA, Dhar S. Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy. Acs Nano. 7: 7392-402. PMID 23899410 DOI: 10.1021/nn403158n  1
2013 Marrache S, Pathak RK, Darley KL, Choi JH, Zaver D, Kolishetti N, Dhar S. Nanocarriers for tracking and treating diseases. Current Medicinal Chemistry. 20: 3500-14. PMID 23834187  1
2013 Marrache S, Dhar S. Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 110: 9445-50. PMID 23671083 DOI: 10.1073/pnas.1301929110  1
2013 Marrache S, Choi JH, Tundup S, Zaver D, Harn DA, Dhar S. Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 215-23. PMID 22832596 DOI: 10.1039/c2ib20125a  1
2012 Marrache S, Dhar S. Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 109: 16288-93. PMID 22991470 DOI: 10.1073/pnas.1210096109  1
2011 Dhar S, Kolishetti N, Lippard SJ, Farokhzad OC. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 1850-5. PMID 21233423 DOI: 10.1073/pnas.1011379108  1
2010 Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 17939-44. PMID 20921363 DOI: 10.1073/pnas.1011368107  1
2010 Lee T, Zhang XA, Dhar S, Faas H, Lippard SJ, Jasanoff A. In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent. Chemistry & Biology. 17: 665-73. PMID 20609416 DOI: 10.1016/j.chembiol.2010.05.009  1
2009 Dhar S, Lippard SJ. Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate Proceedings of the National Academy of Sciences of the United States of America. 106: 22199-22204. PMID 20007777 DOI: 10.1073/pnas.0912276106  1
2009 Dhar S, Daniel WL, Giljohann DA, Mirkin CA, Lippard SJ. Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. Journal of the American Chemical Society. 131: 14652-3. PMID 19778015 DOI: 10.1021/ja9071282  1
2008 Dhar S, Gu FX, Langer R, Farokhza OC, Lippard SJ. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA - PEG nanoparticles Proceedings of the National Academy of Sciences of the United States of America. 105: 17356-17361. PMID 18978032 DOI: 10.1073/pnas.0809154105  1
2008 Tennyson AG, Dhar S, Lippard SJ. Synthesis and characterization of {Ni(NO)}10 and {Co(NO) 2}10 complexes supported by thiolate ligands Journal of the American Chemical Society. 130: 15087-15098. PMID 18928257 DOI: 10.1021/ja803992y  1
2008 Dhar S, Liu Z, Thomale J, Dai H, Lippard SJ. Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. Journal of the American Chemical Society. 130: 11467-76. PMID 18661990 DOI: 10.1021/ja803036e  1
2008 Roy S, Patra AK, Dhar S, Chakravarty AR. Photosensitizer in a molecular bowl and its effect on the DNA-binding and -cleavage activity of 3d-metal scorpionates. Inorganic Chemistry. 47: 5625-33. PMID 18533626 DOI: 10.1021/ic702508r  1
2007 Dhar S, Kodama T, Greenberg MM. Selective detection and quantification of oxidized abasic lesions in DNA. Journal of the American Chemical Society. 129: 8702-3. PMID 17592848 DOI: 10.1021/ja073014e  1
2006 Dhar S, Nethaji M, Chakravarty AR. DNA cleavage on photoexposure at the d-d band in ternary copper(II) complexes using red-light laser. Inorganic Chemistry. 45: 11043-50. PMID 17173464 DOI: 10.1021/ic060328e  1
2005 Dhar S, Nethaji M, Chakravarty AR. Steric protection of a photosensitizer in a N,N-bis[2-(2-pyridyl)ethyl]-2-phenylethylamine-copper(II) bowl that enhances red light-induced DNA cleavage activity. Inorganic Chemistry. 44: 8876-83. PMID 16296843 DOI: 10.1021/ic0505246  1
2005 Dhar S, Chakravarty AR. Photosensitizer in a molecular bowl: steric protection enhancing the photonuclease activity of copper(II) scorpionates. Inorganic Chemistry. 44: 2582-4. PMID 15819541 DOI: 10.1021/ic050085a  1
2005 Patra AK, Dhar S, Nethaji M, Chakravarty AR. Metal-assisted red light-induced DNA cleavage by ternary L-methionine copper(II) complexes of planar heterocyclic bases. Dalton Transactions (Cambridge, England : 2003). 896-902. PMID 15726142 DOI: 10.1039/b416711b  1
2005 Dhar S, Nethaji M, Chakravarty AR. Effect of charge transfer bands on the photo-induced DNA cleavage activity of [1-(2-thiazolylazo)-2-naphtholato]copper(II) complexes. Journal of Inorganic Biochemistry. 99: 805-12. PMID 15708802 DOI: 10.1016/j.jinorgbio.2004.12.014  1
2005 Mukherjee A, Dhar S, Nethaji M, Chakravarty AR. Ternary iron(II) complex with an emissive imidazopyridine arm from Schiff base cyclizations and its oxidative DNA cleavage activity. Dalton Transactions (Cambridge, England : 2003). 349-53. PMID 15616725 DOI: 10.1039/b415864d  1
2005 Dhar S, Nethaji M, Chakravarty AR. Designing molecules for PDT: red light-induced DNA cleavage on disulfide bond activation in a dicopper(II) complex. Dalton Transactions (Cambridge, England : 2003). 344-8. PMID 15616724 DOI: 10.1039/b413410a  1
2004 Dhar S, Nethaji M, Chakravarty AR. Synthetic analogue approach for the functional domains of copper(II) bleomycins and its DNA cleavage activity. Dalton Transactions (Cambridge, England : 2003). 4180-4. PMID 15573170 DOI: 10.1039/b414639e  1
2004 Gupta T, Dhar S, Nethaji M, Chakravarty AR. Bis(dipyridophenazine)copper(II) complex as major groove directing synthetic hydrolase. Dalton Transactions (Cambridge, England : 2003). 1896-900. PMID 15381998 DOI: 10.1039/B404673K  1
2004 Dhar S, Reddy PA, Chakravarty AR. Intramolecular nucleophilic activation promoting efficient hydrolytic cleavage of DNA by (aqua)bis(dipyridoquinoxaline)copper(II) complex. Dalton Transactions (Cambridge, England : 2003). 697-8. PMID 15252488 DOI: 10.1039/b401383b  1
2003 Dhar S, Senapati D, Reddy PA, Das PK, Chakravarty AR. Metal-assisted red light-induced efficient DNA cleavage by dipyridoquinoxaline-copper(II) complex. Chemical Communications (Cambridge, England). 2452-3. PMID 14587727  1
2003 Dhar S, Senapati D, Das PK, Chattopadhyay P, Nethaji M, Chakravarty AR. Ternary copper complexes for photocleavage of DNA by red light: direct evidence for sulfur-to-copper charge transfer and d-d band involvement. Journal of the American Chemical Society. 125: 12118-24. PMID 14518998 DOI: 10.1021/ja036681q  1
2003 Patra AK, Dhar S, Nethaji M, Chakravarty AR. Visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing L-methionine as a photosensitizer. Chemical Communications (Cambridge, England). 1562-3. PMID 12868754  1
2003 Dhar S, Chakravarty AR. Efficient visible light induced nuclease activity of a ternary mono-1,10-phenanthroline copper(II) complex containing 2-(methylthio)ethylsalicylaldimine. Inorganic Chemistry. 42: 2483-5. PMID 12691551 DOI: 10.1021/ic026241k  1
2002 Dhar S, Reddy PA, Nethaji M, Mahadevan S, Saha MK, Chakravarty AR. Effect of steric encumbrance of tris(3-phenylpyrazolyl)borate on the structure and properties of ternary copper(II) complexes having N,N-donor heterocyclic bases. Inorganic Chemistry. 41: 3469-76. PMID 12079466  1
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