Alfred Goldberg - Publications

Harvard Medical School, Boston, MA, United States 

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee D, Zhu Y, Colson L, Wang X, Chen S, Tkacik E, Huang L, Ouyang Q, Goldberg AL, Lu Y. Molecular mechanisms for activation of the 26S proteasome. Biorxiv : the Preprint Server For Biology. PMID 37214989 DOI: 10.1101/2023.05.09.540094  0.37
2022 Lee D, Goldberg AL. 26S proteasomes become stably activated upon heat shock when ubiquitination and protein degradation increase. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122482119. PMID 35704754 DOI: 10.1073/pnas.2122482119  0.33
2022 Collins GA, Sha Z, Kuo CL, Erbil B, Goldberg AL. Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation. The Journal of Biological Chemistry. 101875. PMID 35358511 DOI: 10.1016/j.jbc.2022.101875  0.366
2021 Goldberg AL, Kim HT, Lee D, Collins GA. Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation. Biomolecules. 11. PMID 34067263 DOI: 10.3390/biom11060779  0.362
2020 VerPlank JJS, Tyrkalska SD, Fleming A, Rubinsztein DC, Goldberg AL. cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases. Proceedings of the National Academy of Sciences of the United States of America. 117: 14220-14230. PMID 32513741 DOI: 10.1073/pnas.2003277117  0.337
2020 Collins GA, Goldberg AL. Proteins containing ubiquitin-like (Ubl) domains not only bind to 26S proteasomes but also induce their activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071216 DOI: 10.1073/pnas.1915534117  0.395
2019 Sha Z, Blyszcz T, González-Prieto R, Vertegaal ACO, Goldberg AL. Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies. The Journal of Biological Chemistry. PMID 31285264 DOI: 10.1074/jbc.RA119.009147  0.367
2019 Jiang TX, Zou JB, Zhu QQ, Liu CH, Wang GF, Du TT, Luo ZY, Guo F, Zhou LM, Liu JJ, Zhang W, Shu YS, Yu L, Li P, Ronai ZA, ... ... Goldberg AL, et al. SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31213539 DOI: 10.1073/Pnas.1901039116  0.713
2019 VerPlank JJS, Lokireddy S, Zhao J, Goldberg AL. 26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30782827 DOI: 10.1073/pnas.1809254116  0.327
2018 Fraga H, Rodriguez B, Bardera A, Cid C, Akopian T, Kandror O, Park A, Colmenarejo G, Lelievre J, Goldberg A. Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis. Analytical Biochemistry. PMID 30543804 DOI: 10.1016/J.Ab.2018.12.004  0.324
2018 Kim HT, Goldberg AL. UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30487212 DOI: 10.1073/pnas.1808731115  0.376
2018 Lee D, Takayama S, Goldberg AL. ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254168 DOI: 10.1073/pnas.1809934115  0.381
2018 Kim HT, Collins GA, Goldberg AL. Measurement of the Multiple Activities of 26S Proteasomes. Methods in Molecular Biology (Clifton, N.J.). 1844: 289-308. PMID 30242717 DOI: 10.1007/978-1-4939-8706-1_19  0.306
2018 Sha Z, Zhao J, Goldberg AL. Measuring the Overall Rate of Protein Breakdown in Cells and the Contributions of the Ubiquitin-Proteasome and Autophagy-Lysosomal Pathways. Methods in Molecular Biology (Clifton, N.J.). 1844: 261-276. PMID 30242715 DOI: 10.1007/978-1-4939-8706-1_17  0.357
2018 Weinhäupl K, Brennich M, Kazmaier U, Lelievre J, Ballell L, Goldberg A, Schanda P, Fraga H. The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from . The Journal of Biological Chemistry. 293: 8379-8393. PMID 29632076 DOI: 10.1074/Jbc.Ra118.002251  0.403
2018 Sha Z, Schnell HM, Ruoff K, Goldberg A. Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation. The Journal of Cell Biology. PMID 29535191 DOI: 10.1083/Jcb.201708168  0.456
2018 Goldberg A, Lokireddy S, Kim H, Kuo C, VerPlank J. NEW INSIGHTS INTO THE PROTEASOME FUNCTION AND DEGRADATION OF MISFOLDED PROTEINS Innovation in Aging. 2: 387-387. DOI: 10.1093/Geroni/Igy023.1443  0.373
2017 VerPlank JJS, Lokireddy S, Feltri ML, Goldberg AL, Wrabetz L. Impairment of protein degradation and proteasome function in hereditary neuropathies. Glia. PMID 29076578 DOI: 10.1002/Glia.23251  0.309
2017 VerPlank JJS, Goldberg AL. Regulating protein breakdown through proteasome phosphorylation. The Biochemical Journal. 474: 3355-3371. PMID 28947610 DOI: 10.1042/BCJ20160809  0.325
2017 Collins GA, Goldberg AL. The Logic of the 26S Proteasome. Cell. 169: 792-806. PMID 28525752 DOI: 10.1016/j.cell.2017.04.023  0.351
2017 Kim HT, Goldberg AL. The Deubiquitinating Enzyme Usp14 Allosterically Inhibits Multiple Proteasomal Activities and Ubiquitin-Independent Proteolysis. The Journal of Biological Chemistry. PMID 28416611 DOI: 10.1074/jbc.M116.763128  0.37
2017 Kuo CL, Goldberg AL. Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396413 DOI: 10.1073/pnas.1701734114  0.376
2017 Volodin A, Kosti I, Goldberg AL, Cohen S. Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096335 DOI: 10.1073/pnas.1612988114  0.347
2016 Zhao J, Goldberg AL. Coordinate regulation of autophagy and the ubiquitin proteasome system by MTOR. Autophagy. 0. PMID 27459110 DOI: 10.1080/15548627.2016.1205770  0.364
2016 Lee DH, Sherman MY, Goldberg AL. The requirements of yeast Hsp70 of SSA family for the ubiquitin-dependent degradation of short-lived and abnormal proteins. Biochemical and Biophysical Research Communications. PMID 27178214 DOI: 10.1016/j.bbrc.2016.05.046  0.346
2016 Famulla K, Sass P, Malik I, Akopian T, Kandror O, Alber M, Hinzen B, Ruebsamen-Schaeff H, Kalscheuer R, Goldberg AL, Brötz-Oesterhelt H. Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease. Molecular Microbiology. 101: 194-209. PMID 26919556 DOI: 10.1111/mmi.13362  0.336
2016 Famulla K, Sass P, Malik I, Akopian T, Kandror O, Alber M, Hinzen B, Ruebsamen-Schaeff H, Kalscheuer R, Goldberg AL, Brötz-Oesterhelt H. Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease Molecular Microbiology. DOI: 10.1111/mmi.13362  0.337
2015 Lokireddy S, Kukushkin NV, Goldberg AL. cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 26669444 DOI: 10.1073/pnas.1522332112  0.378
2015 Zhao J, Zhai B, Gygi SP, Goldberg AL. mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26669439 DOI: 10.1073/Pnas.1521919112  0.371
2015 Tsvetkov P, Mendillo ML, Zhao J, Carette JE, Merrill PH, Cikes D, Varadarajan M, van Diemen FR, Penninger JM, Goldberg AL, Brummelkamp TR, Santagata S, Lindquist S. Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome. Elife. 4. PMID 26327695 DOI: 10.7554/Elife.08467  0.314
2015 Aufderheide A, Beck F, Stengel F, Hartwig M, Schweitzer A, Pfeifer G, Goldberg AL, Sakata E, Baumeister W, Förster F. Structural characterization of the interaction of Ubp6 with the 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. PMID 26130806 DOI: 10.1073/Pnas.1510449112  0.333
2015 Sandu C, Chandramouli N, Glickman JF, Molina H, Kuo CL, Kukushkin N, Goldberg AL, Steller H. Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates. Journal of Cellular and Molecular Medicine. PMID 26033448 DOI: 10.1111/jcmm.12602  0.37
2014 Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL. Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates. The Embo Journal. 33: 1159-76. PMID 24811749 DOI: 10.1002/Embj.201386906  0.402
2014 Gavrish E, Sit CS, Cao S, Kandror O, Spoering A, Peoples A, Ling L, Fetterman A, Hughes D, Bissell A, Torrey H, Akopian T, Mueller A, Epstein S, Goldberg A, et al. Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2. Chemistry & Biology. 21: 509-18. PMID 24684906 DOI: 10.1016/J.Chembiol.2014.01.014  0.339
2013 Peth A, Nathan JA, Goldberg AL. The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome. The Journal of Biological Chemistry. 288: 29215-22. PMID 23965995 DOI: 10.1074/jbc.M113.482570  0.308
2013 Qian MX, Pang Y, Liu CH, Haratake K, Du BY, Ji DY, Wang GF, Zhu QQ, Song W, Yu Y, Zhang XX, Huang HT, Miao S, Chen LB, Zhang ZH, ... ... Goldberg AL, et al. Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell. 153: 1012-24. PMID 23706739 DOI: 10.1016/J.Cell.2013.04.032  0.659
2013 Nathan JA, Spinnenhirn V, Schmidtke G, Basler M, Groettrup M, Goldberg AL. Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins. Cell. 152: 1184-94. PMID 23452861 DOI: 10.1016/j.cell.2013.01.037  0.347
2013 Peth A, Kukushkin N, Bossé M, Goldberg AL. Ubiquitinated proteins activate the proteasomal ATPases by binding to Usp14 or Uch37 homologs. The Journal of Biological Chemistry. 288: 7781-90. PMID 23341450 DOI: 10.1074/jbc.M112.441907  0.364
2012 Berko D, Tabachnick-Cherny S, Shental-Bechor D, Cascio P, Mioletti S, Levy Y, Admon A, Ziv T, Tirosh B, Goldberg AL, Navon A. The direction of protein entry into the proteasome determines the variety of products and depends on the force needed to unfold its two termini. Molecular Cell. 48: 601-11. PMID 23041283 DOI: 10.1016/J.Molcel.2012.08.029  0.723
2012 Bhutani N, Piccirillo R, Hourez R, Venkatraman P, Goldberg AL. Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes. The Journal of Biological Chemistry. 287: 17471-82. PMID 22451661 DOI: 10.1074/jbc.M112.352781  0.344
2012 Raju RM, Unnikrishnan M, Rubin DH, Krishnamoorthy V, Kandror O, Akopian TN, Goldberg AL, Rubin EJ. Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection. Plos Pathogens. 8: e1002511. PMID 22359499 DOI: 10.1371/Journal.Ppat.1002511  0.353
2012 Besche HC, Goldberg AL. Affinity purification of mammalian 26S proteasomes using an ubiquitin-like domain. Methods in Molecular Biology (Clifton, N.J.). 832: 423-32. PMID 22350902 DOI: 10.1007/978-1-61779-474-2_29  0.307
2012 Smith DM, Fraga H, Reis C, Goldberg A. Allosteric Regulation of Nucleotide Binding to the Proteasomal ATPases Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.137  0.371
2011 Dange T, Smith D, Noy T, Rommel PC, Jurzitza L, Cordero RJ, Legendre A, Finley D, Goldberg AL, Schmidt M. Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism. The Journal of Biological Chemistry. 286: 42830-9. PMID 22025621 DOI: 10.1074/jbc.M111.300178  0.355
2011 Lee D, Goldberg A. Atrogin1/MAFbx: what atrophy, hypertrophy, and cardiac failure have in common. Circulation Research. 109: 123-6. PMID 21737813 DOI: 10.1161/Circresaha.111.248872  0.458
2011 Bader M, Benjamin S, Wapinski OL, Smith DM, Goldberg AL, Steller H. A conserved F box regulatory complex controls proteasome activity in Drosophila. Cell. 145: 371-82. PMID 21529711 DOI: 10.1016/j.cell.2011.03.021  0.348
2010 Peth A, Uchiki T, Goldberg AL. ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation. Molecular Cell. 40: 671-81. PMID 21095592 DOI: 10.1016/J.Molcel.2010.11.002  0.327
2010 Menzies FM, Hourez R, Imarisio S, Raspe M, Sadiq O, Chandraratna D, O'Kane C, Rock KL, Reits E, Goldberg AL, Rubinsztein DC. Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. Human Molecular Genetics. 19: 4573-86. PMID 20829225 DOI: 10.1093/hmg/ddq385  0.32
2010 Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y. Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. The Embo Journal. 29: 692-702. PMID 20019667 DOI: 10.1038/Emboj.2009.382  0.304
2010 Lee DH, Goldberg AL. Hsp104 is essential for the selective degradation in yeast of polyglutamine expanded ataxin-1 but not most misfolded proteins generally. Biochemical and Biophysical Research Communications. 391: 1056-61. PMID 19995551 DOI: 10.1016/j.bbrc.2009.12.018  0.305
2009 Peth A, Besche HC, Goldberg AL. Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening. Molecular Cell. 36: 794-804. PMID 20005843 DOI: 10.1016/j.molcel.2009.11.015  0.362
2009 Cohen S, Brault JJ, Gygi SP, Glass DJ, Valenzuela DM, Gartner C, Latres E, Goldberg AL. During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. The Journal of Cell Biology. 185: 1083-95. PMID 19506036 DOI: 10.1083/Jcb.200901052  0.3
2009 Kim HT, Kim KP, Uchiki T, Gygi SP, Goldberg AL. S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains. The Embo Journal. 28: 1867-77. PMID 19387488 DOI: 10.1038/Emboj.2009.115  0.335
2009 Besche HC, Haas W, Gygi SP, Goldberg AL. Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins. Biochemistry. 48: 2538-49. PMID 19182904 DOI: 10.1021/Bi802198Q  0.36
2007 Liu CH, Goldberg AL, Qiu XB. New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis. Chang Gung Medical Journal. 30: 469-79. PMID 18350730  0.735
2007 Xu L, Zhu J, Hu X, Zhu H, Kim HT, LaBaer J, Goldberg A, Yuan J. c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1. Molecular Cell. 28: 914-22. PMID 18082613 DOI: 10.1016/J.Molcel.2007.10.027  0.407
2007 Horwitz AA, Navon A, Groll M, Smith DM, Reis C, Goldberg AL. ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea. The Journal of Biological Chemistry. 282: 22921-9. PMID 17553803 DOI: 10.1074/Jbc.M702846200  0.583
2007 Goldberg AL. Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy. Biochemical Society Transactions. 35: 12-7. PMID 17212580 DOI: 10.1042/BST0350012  0.301
2006 Qiu XB, Ouyang SY, Li CJ, Miao S, Wang L, Goldberg AL. hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. The Embo Journal. 25: 5742-53. PMID 17139257 DOI: 10.1038/sj.emboj.7601450  0.725
2006 Smith DM, Benaroudj N, Goldberg A. Proteasomes and their associated ATPases: a destructive combination. Journal of Structural Biology. 156: 72-83. PMID 16919475 DOI: 10.1016/J.Jsb.2006.04.012  0.423
2006 Kisselev AF, Callard A, Goldberg AL. Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. The Journal of Biological Chemistry. 281: 8582-90. PMID 16455650 DOI: 10.1074/jbc.M509043200  0.315
2005 Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL. ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Molecular Cell. 20: 687-98. PMID 16337593 DOI: 10.1016/J.Molcel.2005.10.019  0.338
2005 Kisselev AF, Goldberg AL. Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates. Methods in Enzymology. 398: 364-78. PMID 16275343 DOI: 10.1016/S0076-6879(05)98030-0  0.309
2005 Cascio P, Goldberg AL. Preparation of hybrid (19S-20S-PA28) proteasome complexes and analysis of peptides generated during protein degradation. Methods in Enzymology. 398: 336-52. PMID 16275341 DOI: 10.1016/S0076-6879(05)98028-2  0.311
2004 Qiu XB, Goldberg AL. The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9. The Journal of Biological Chemistry. 280: 174-82. PMID 15507451 DOI: 10.1074/JBC.M411430200  0.688
2004 Qiu XB, Markant SL, Yuan J, Goldberg AL. Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis. The Embo Journal. 23: 800-10. PMID 14765125 DOI: 10.1038/Sj.Emboj.7600075  0.714
2003 Benaroudj N, Zwickl P, Seemüller E, Baumeister W, Goldberg AL. ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Molecular Cell. 11: 69-78. PMID 12535522 DOI: 10.1016/S1097-2765(02)00775-X  0.363
2002 Qiu XB, Goldberg AL. Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proceedings of the National Academy of Sciences of the United States of America. 99: 14843-8. PMID 12411582 DOI: 10.1073/pnas.232580999  0.69
2002 Kisselev AF, Kaganovich D, Goldberg AL. Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings. The Journal of Biological Chemistry. 277: 22260-70. PMID 11927581 DOI: 10.1074/jbc.M112360200  0.638
2001 Navon A, Goldberg AL. Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome Molecular Cell. 8: 1339-1349. PMID 11779508 DOI: 10.1016/S1097-2765(01)00407-5  0.644
2001 Gomes MD, Lecker SH, Jagoe RT, Navon A, Goldberg AL. Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy. Proceedings of the National Academy of Sciences of the United States of America. 98: 14440-5. PMID 11717410 DOI: 10.1073/Pnas.251541198  0.596
2001 Jagoe RT, Goldberg AL. What do we really know about the ubiquitin-proteasome pathway in muscle atrophy? Current Opinion in Clinical Nutrition and Metabolic Care. 4: 183-90. PMID 11517350 DOI: 10.1097/00075197-200105000-00003  0.38
2001 Benaroudj N, Tarcsa E, Cascio P, Goldberg AL. The unfolding of substrates and ubiquitin-independent protein degradation by proteasomes. Biochimie. 83: 311-8. PMID 11295491 DOI: 10.1016/S0300-9084(01)01244-5  0.365
2001 Benaroudj N, Goldberg AL. PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone. Nature Cell Biology. 2: 833-9. PMID 11056539 DOI: 10.1038/35041081  0.339
2000 Huang HC, Sherman MY, Kandror O, Goldberg AL. The molecular chaperone DnaJ is required for the degradation of a soluble abnormal protein in Escherichia coli. The Journal of Biological Chemistry. 276: 3920-8. PMID 11062236 DOI: 10.1074/JBC.M002937200  0.337
1999 Kandror O, Sherman M, Goldberg A. Rapid Degradation of an Abnormal Protein in Escherichia coli Proceeds through Repeated Cycles of Association with GroEL Journal of Biological Chemistry. 274: 37743-37749. PMID 10608834 DOI: 10.1074/Jbc.274.53.37743  0.455
1999 Zwickl P, Ng D, Woo KM, Klenk HP, Goldberg AL. An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes. The Journal of Biological Chemistry. 274: 26008-14. PMID 10473546 DOI: 10.1074/jbc.274.37.26008  0.309
1998 Solomon V, Lecker SH, Goldberg AL. The N-end rule pathway catalyzes a major fraction of the protein degradation in skeletal muscle. The Journal of Biological Chemistry. 273: 25216-22. PMID 9737984 DOI: 10.1074/jbc.273.39.25216  0.381
1997 Craiu A, Akopian T, Goldberg A, Rock KL. Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide Proceedings of the National Academy of Sciences of the United States of America. 94: 10850-10855. PMID 9380723 DOI: 10.1073/Pnas.94.20.10850  0.371
1997 Seol JH, Yoo SJ, Shin DH, Shim YK, Kang MS, Goldberg AL, Chung CH. The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase. European Journal of Biochemistry / Febs. 247: 1143-50. PMID 9288941 DOI: 10.1111/J.1432-1033.1997.01143.X  0.337
1997 Goldberg AL, Akopian TN, Kisselev AF, Lee DH. Protein degradation by the proteasome and dissection of its in vivo importance with synthetic inhibitors. Molecular Biology Reports. 24: 69-75. PMID 9228284 DOI: 10.1023/A:1006860828265  0.336
1997 Rubin DM, Van Nocker S, Glickman M, Coux O, Wefes I, Sadis S, Fu H, Goldberg A, Vierstra R, Finley D. ATPase and ubiquitin-binding proteins of the yeast proteasome Molecular Biology Reports. 24: 17-26. PMID 9228276 DOI: 10.1023/A:1006844305067  0.436
1997 Akopian TN, Kisselev AF, Goldberg AL. Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum. The Journal of Biological Chemistry. 272: 1791-8. PMID 8999862 DOI: 10.1074/jbc.272.3.1791  0.338
1996 Lee DH, Goldberg AL. Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degradation in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 271: 27280-4. PMID 8910302 DOI: 10.1074/jbc.271.44.27280  0.348
1996 Solomon V, Goldberg AL. Importance of the ATP-ubiquitin-proteasome pathway in the degradation of soluble and myofibrillar proteins in rabbit muscle extracts. The Journal of Biological Chemistry. 271: 26690-7. PMID 8900146 DOI: 10.1074/JBC.271.43.26690  0.377
1996 Sherman MY, Goldberg AL. Involvement of molecular chaperones in intracellular protein breakdown. Exs. 77: 57-78. PMID 8856969 DOI: 10.1007/978-3-0348-9088-5_5  0.363
1996 Coux O, Tanaka K, Goldberg AL. Structure and functions of the 20S and 26S proteasomes. Annual Review of Biochemistry. 65: 801-47. PMID 8811196 DOI: 10.1146/ANNUREV.BI.65.070196.004101  0.372
1996 Yoo SJ, Seol JH, Shin DH, Rohrwild M, Kang MS, Tanaka K, Goldberg AL, Chung CH. Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli. The Journal of Biological Chemistry. 271: 14035-40. PMID 8662828 DOI: 10.1074/jbc.271.24.14035  0.318
1996 Rohrwild M, Coux O, Huang HC, Moerschell RP, Yoo SJ, Seol JH, Chung CH, Goldberg AL. HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome. Proceedings of the National Academy of Sciences of the United States of America. 93: 5808-13. PMID 8650174 DOI: 10.1073/PNAS.93.12.5808  0.336
1996 Grimm LM, Goldberg AL, Poirier GG, Schwartz LM, Osborne BA. Proteasomes play an essential role in thymocyte apoptosis. The Embo Journal. 15: 3835-3844. DOI: 10.1002/J.1460-2075.1996.Tb00757.X  0.314
1995 Wing SS, Haas AL, Goldberg AL. Increase in ubiquitin-protein conjugates concomitant with the increase in proteolysis in rat skeletal muscle during starvation and atrophy denervation. The Biochemical Journal. 307: 639-45. PMID 7741691 DOI: 10.1042/Bj3070639  0.332
1995 Gaczynska M, Rock KL, Goldberg AL. Role of proteasomes in antigen presentation. Enzyme & Protein. 47: 354-69. PMID 7697133 DOI: 10.1159/000468693  0.332
1995 Kandror O, Sherman M, Rhode M, Goldberg AL. Trigger factor is involved in GroEL-dependent protein degradation in Escherichia coli and promotes binding of GroEL to unfolded proteins. The Embo Journal. 14: 6021-6027. DOI: 10.1002/j.1460-2075.1995.tb00290.x  0.32
1994 Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 78: 761-71. PMID 8087844 DOI: 10.1016/S0092-8674(94)90462-6  0.314
1992 Driscoll J, Frydman J, Goldberg AL. An ATP-stabilized inhibitor of the proteasome is a component of the 1500-kDa ubiquitin conjugate-degrading complex Proceedings of the National Academy of Sciences of the United States of America. 89: 4986-4990. PMID 1317579 DOI: 10.1073/Pnas.89.11.4986  0.581
1991 Sherman MY, Goldberg AL. Formation in vitro of complexes between an abnormal fusion protein and the heat shock proteins from Escherichia coli and yeast mitochondria. Journal of Bacteriology. 173: 7249-56. PMID 1938919 DOI: 10.1128/jb.173.22.7249-7256.1991  0.331
1990 Driscoll J, Goldberg AL. The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins. Journal of Biological Chemistry. 265: 4789-4792. DOI: 10.1016/s0021-9258(19)34041-4  0.326
1989 Matthews W, Driscoll J, Tanaka K, Ichihara A, Goldberg AL. Involvement of the proteasome in various degradative processes in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 2597-601. PMID 2539595 DOI: 10.1073/PNAS.86.8.2597  0.332
1989 Driscoll J, Goldberg AL. Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin. Proceedings of the National Academy of Sciences of the United States of America. 86: 787-91. PMID 2536933 DOI: 10.1073/PNAS.86.3.787  0.307
1987 Fagan JM, Waxman L, Goldberg AL. Skeletal muscle and liver contain a soluble ATP + ubiquitin-dependent proteolytic system. The Biochemical Journal. 243: 335-43. PMID 2820375 DOI: 10.1042/BJ2430335  0.339
1986 Edmunds T, Goldberg AL. Role of ATP hydrolysis in the degradation of proteins by protease La from Escherichia coli Journal of Cellular Biochemistry. 32: 187-191. PMID 3536972 DOI: 10.1002/JCB.240320304  0.301
1986 Waxman L, Goldberg AL. Selectivity of intracellular proteolysis: protein substrates activate the ATP-dependent protease (La). Science (New York, N.Y.). 232: 500-3. PMID 2938257 DOI: 10.1126/SCIENCE.2938257  0.36
1985 Waxman L, Fagan JM, Tanaka K, Goldberg AL. A soluble ATP-dependent system for protein degradation from murine erythroleukemia cells. Evidence for a protease which requires ATP hydrolysis but not ubiquitin. Journal of Biological Chemistry. 260: 11994-12000. DOI: 10.1016/s0021-9258(17)38975-5  0.32
1984 Tanaka K, Waxman L, Goldberg AL. Vanadate inhibits the ATP-dependent degradation of proteins in reticulocytes without affecting ubiquitin conjugation. Journal of Biological Chemistry. 259: 2803-2809. DOI: 10.1016/s0021-9258(17)43217-0  0.358
1984 Malek L, Bogorad L, Ayers AR, Goldberg AL. Newly synthesized proteins are degraded by an ATP-stimulated proteolytic process in isolated pea chloroplasts Febs Letters. 166: 253-257. DOI: 10.1016/0014-5793(84)80090-3  0.304
1983 Boches FS, Goldberg AL. Role for the adenosine triphosphate-dependent proteolytic pathway in reticulocyte maturation. Science (New York, N.Y.). 215: 978-80. PMID 7156977 DOI: 10.1126/SCIENCE.7156977  0.325
1983 Tanaka K, Waxman L, Goldberg AL. ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin. The Journal of Cell Biology. 96: 1580-5. PMID 6304111 DOI: 10.1083/JCB.96.6.1580  0.315
1982 Desautels M, Goldberg AL. Liver mitochondria contain an ATP-dependent, vanadate-sensitive pathway for the degradation of proteins. Proceedings of the National Academy of Sciences of the United States of America. 79: 1869-73. PMID 7043466 DOI: 10.1073/PNAS.79.6.1869  0.31
1982 Goldberg AL, Boches FS. Oxidized proteins in erythrocytes are rapidly degraded by the adenosine triphosphate-dependent proteolytic system. Science (New York, N.Y.). 215: 1107-9. PMID 7038874 DOI: 10.1126/SCIENCE.7038874  0.328
1981 Libby P, Goldberg AL. Comparison of the control and pathways for degradation of the acetylcholine receptor and average protein in cultured muscle cells Journal of Cellular Physiology. 107: 185-194. PMID 7019224 DOI: 10.1002/JCP.1041070204  0.314
1981 Voellmy RW, Goldberg AL. ATP-stimulated endoprotease is associated with the cell membrane of E. coli. Nature. 290: 419-21. PMID 7012639 DOI: 10.1038/290419A0  0.359
1981 Goldberg AL, Strnad NP, Swamy KH. Studies of the ATP dependence of protein degradation in cells and cell extracts. Ciba Foundation Symposium. 227-51. PMID 399890 DOI: 10.1002/9780470720585.CH15  0.336
1980 Neff NT, DeMartino GN, Goldberg AL. The effect of protease inhibitors and decreased temperature on the degradation of different classes of proteins in cultured hepatocytes. Journal of Cellular Physiology. 101: 439-57. PMID 528571 DOI: 10.1002/JCP.1041010311  0.316
1977 Kowit JD, Choy WN, Champe SP, Goldberg AL. Role and location of "protease I" from Escherichia coli. Journal of Bacteriology. 128: 776-84. PMID 791931 DOI: 10.1128/jb.128.3.776-784.1976  0.316
1976 Li J, Goldberg A. Effects of food deprivation on protein synthesis and degradation in rat skeletal muscles. American Journal of Physiology. 231: 441-448. PMID 961895 DOI: 10.1152/Ajplegacy.1976.231.2.441  0.333
1972 Goldberg AL. Correlation between rates of degradation of bacterial proteins in vivo and their sensitivity to proteases. Proceedings of the National Academy of Sciences of the United States of America. 69: 2640-4. PMID 4560693 DOI: 10.1073/PNAS.69.9.2640  0.311
1972 Goldberg AL. Degradation of abnormal proteins in Escherichia coli (protein breakdown-protein structure-mistranslation-amino acid analogs-puromycin). Proceedings of the National Academy of Sciences of the United States of America. 69: 422-6. PMID 4551144 DOI: 10.1073/PNAS.69.2.422  0.315
1971 Goldberg AL. A role of aminoacyl-tRNA in the regulation of protein breakdown in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 68: 362-6. PMID 5277086 DOI: 10.1073/PNAS.68.2.362  0.313
1969 Goldberg AL, Goodman HM. Effects od disuse and denervation on amino acid transport by skeletal muscle. The American Journal of Physiology. 216: 1116-9. PMID 5768061 DOI: 10.1152/Ajplegacy.1969.216.5.1116  0.469
1969 Goldberg AL, Goodman HM. Amino acid transport during work-induced growth of skeletal muscle. The American Journal of Physiology. 216: 1111-5. PMID 5768060 DOI: 10.1152/Ajplegacy.1969.216.5.1111  0.479
1969 Goldberg AL, Goodman HM. Relationship between cortisone and muscle work in determining muscle size. The Journal of Physiology. 200: 667-75. PMID 5765854 DOI: 10.1113/jphysiol.1969.sp008715  0.452
1969 Goldberg AL, Goodman HM. Relationship between growth hormone and muscular work in determining muscle size. The Journal of Physiology. 200: 655-66. PMID 5765853 DOI: 10.1113/jphysiol.1969.sp008714  0.427
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