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Heidi E. Hamm - Publications

Pharmacology Vanderbilt University School of Medicine, Nashville, TN, United States 
G proteins

178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Temple KJ, Duvernay MT, Young SE, Wen W, Wu W, Maeng J, Blobaum AL, Stauffer SR, Hamm HE, Lindsley CW. Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with In Vivo Utility and Activity Against γ-Thrombin. Journal of Medicinal Chemistry. PMID 27482618 DOI: 10.1021/Acs.Jmedchem.6B00928  1
2015 Zurawski Z, Rodriguez S, Hyde K, Alford S, Hamm HE. Gβγ binds to the extreme C-terminus of SNAP25 to mediate the action of Gi/o-coupled GPCRs. Molecular Pharmacology. PMID 26519224 DOI: 10.1124/Mol.115.101600  1
2014 Wen W, Young SE, Duvernay MT, Schulte ML, Nance KD, Melancon BJ, Engers J, Locuson CW, Wood MR, Daniels JS, Wu W, Lindsley CW, Hamm HE, Stauffer SR. Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354. Bioorganic & Medicinal Chemistry Letters. 24: 4708-13. PMID 25176330 DOI: 10.1016/J.Bmcl.2014.08.021  1
2014 Cleator JH, Duvernay MT, Holinstat M, Colowick NE, Hudson WJ, Song Y, Harrell FE, Hamm HE. Racial differences in resistance to P2Y12receptor antagonists in type 2 diabetic subjects Journal of Pharmacology and Experimental Therapeutics. 351: 33-43. PMID 25052834 DOI: 10.1124/Jpet.114.215616  1
2014 Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE. A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit. The Journal of Biological Chemistry. 289: 24475-87. PMID 25037222 DOI: 10.1074/Jbc.M114.572875  1
2014 Thaker TM, Sarwar M, Preininger AM, Hamm HE, Iverson TM. A transient interaction between the phosphate binding loop and switch i contributes to the allosteric network between receptor and nucleotide in Gαi1 Journal of Biological Chemistry. 289: 11331-11341. PMID 24596087 DOI: 10.1074/Jbc.M113.539064  1
2014 Betke KM, Rose KL, Friedman DB, Baucum AJ, Hyde K, Schey KL, Hamm HE. Differential localization of G protein βγ subunits. Biochemistry. 53: 2329-43. PMID 24568373 DOI: 10.1021/Bi500091P  1
2014 Hamid E, Church E, Wells CA, Zurawski Z, Hamm HE, Alford S. Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 260-74. PMID 24381287 DOI: 10.1523/Jneurosci.3633-12.2014  1
2014 Alexander NS, Preininger AM, Kaya AI, Stein RA, Hamm HE, Meiler J. Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release. Nature Structural & Molecular Biology. 21: 56-63. PMID 24292645 DOI: 10.1038/Nsmb.2705  1
2013 Li X, Roszko I, Sepich DS, Ni M, Hamm HE, Marlow FL, Solnica-Krezel L. Gpr125 modulates Dishevelled distribution and planar cell polarity signaling Development (Cambridge). 140: 3028-3039. PMID 23821037 DOI: 10.1242/Dev.094839  1
2013 Young SE, Duvernay MT, Schulte ML, Lindsley CW, Hamm HE. Synthesis of indole derived protease-activated receptor 4 antagonists and characterization in human platelets. Plos One. 8: e65528. PMID 23776495 DOI: 10.1371/Journal.Pone.0065528  1
2013 Preininger AM, Meiler J, Hamm HE. Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective. Journal of Molecular Biology. 425: 2288-98. PMID 23602809 DOI: 10.1016/J.Jmb.2013.04.011  1
2013 Hamm HE, Kaya AI, Gilbert JA, Preininger AM. Linking receptor activation to changes in Sw I and II of Gα proteins Journal of Structural Biology. 184: 63-74. PMID 23466875 DOI: 10.1016/J.Jsb.2013.02.016  1
2013 Duvernay M, Young S, Gailani D, Schoenecker J, Hamm HE, Hamm H. Protease-activated receptor (PAR) 1 and PAR4 differentially regulate factor V expression from human platelets. Molecular Pharmacology. 83: 781-92. PMID 23307185 DOI: 10.1124/Mol.112.083477  1
2013 Natarajan C, Hata AN, Hamm HE, Zent R, Breyer RM. Extracellular loop II modulates GTP sensitivity of the prostaglandin EP3 receptor Molecular Pharmacology. 83: 206-216. PMID 23087260 DOI: 10.1124/Mol.112.080473  1
2013 Holinstat M, Colowick NE, Hudson WJ, Blakemore D, Chen Q, Hamm HE, Cleator JH. Dichotomous effects of exposure to bivalirudin in patients undergoing percutaneous coronary intervention on protease-activated receptor-mediated platelet activation Journal of Thrombosis and Thrombolysis. 35: 209-222. PMID 23054462 DOI: 10.1007/S11239-012-0812-9  1
2012 Wells CA, Zurawski Z, Betke KM, Yim YY, Hyde K, Rodriguez S, Alford S, Hamm HE. Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25. Molecular Pharmacology. 82: 1136-49. PMID 22962332 DOI: 10.1124/Mol.112.080507  1
2012 Makino CL, Wen XH, Michaud NA, Covington HI, DiBenedetto E, Hamm HE, Lem J, Caruso G. Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics. Plos One. 7: e37832. PMID 22662234 DOI: 10.1371/Journal.Pone.0037832  1
2012 Preininger AM, Kaya AI, Gilbert JA, Busenlehner LS, Armstrong RN, Hamm HE. Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution. Biochemistry. 51: 1911-24. PMID 22329346 DOI: 10.1021/Bi201472C  1
2012 Betke KM, Wells CA, Hamm HE. GPCR mediated regulation of synaptic transmission Progress in Neurobiology. 96: 304-321. PMID 22307060 DOI: 10.1016/J.Pneurobio.2012.01.009  1
2012 O'Neill KR, Stutz CM, Mignemi NA, Cole H, Murry MR, Nyman JS, Hamm H, Schoenecker JG. Fracture healing in protease-activated receptor-2 deficient mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1271-6. PMID 22247070 DOI: 10.1002/Jor.22071  1
2012 Thaker TM, Kaya AI, Preininger AM, Hamm HE, Iverson TM. Allosteric mechanisms of G protein-coupled receptor signaling: A structural perspective Methods in Molecular Biology. 796: 133-174. PMID 22052489 DOI: 10.1007/978-1-61779-334-9_8  1
2012 Ichikawa J, Cole HA, Magnussen RA, Mignemi NA, Butler M, Holt GE, O'Rear L, Yuasa M, Pabla B, Haro H, Cates JMM, Hamm HE, Schwartz HS, Schoenecker JG. Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: Procoagulant nature of osteosarcoma Cancer. 118: 2494-2506. PMID 21953059 DOI: 10.1002/Cncr.26518  1
2012 Wells CA, Betke KM, Lindsley CW, Hamm HE. Label-free detection of G protein-SNARE interactions and screening for small molecule modulators Acs Chemical Neuroscience. 3: 69-78. DOI: 10.1021/cn200102d  1
2011 Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL. Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit. Proceedings of the National Academy of Sciences of the United States of America. 108: 9420-4. PMID 21606326 DOI: 10.1073/Pnas.1105810108  1
2011 Caruso G, Bisegna P, Andreucci D, Lenoci L, Gurevich VV, Hamm HE, DiBenedetto E. Identification of key factors that reduce the variability of the single photon response Proceedings of the National Academy of Sciences of the United States of America. 108: 7804-7807. PMID 21518901 DOI: 10.1073/Pnas.1018960108  1
2011 Kaya AI, Thaker TM, Preininger AM, Iverson TM, Hamm HE. Coupling efficiency of rhodopsin and transducin in bicelles Biochemistry. 50: 3193-3203. PMID 21375271 DOI: 10.1021/Bi200037J  1
2011 Lenoci L, Duvernay M, Satchell S, DiBenedetto E, Hamm HE. Mathematical model of PAR1-mediated activation of human platelets Molecular Biosystems. 7: 1129-1137. PMID 21229145 DOI: 10.1039/C0Mb00250J  1
2011 Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE. Protease-activated receptor signaling in platelets activates cytosolic phospholipase a2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 435-442. PMID 21127289 DOI: 10.1161/Atvbaha.110.219527  1
2010 Caruso G, Bisegna P, Lenoci L, Andreucci D, Gurevich VV, Hamm HE, DiBenedetto E. Kinetics of rhodopsin deactivation and its role in regulating recovery and reproducibility of rod photoresponse Plos Computational Biology. 6. PMID 21200415 DOI: 10.1371/Journal.Pcbi.1001031  1
2010 Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Science Signaling. 3: ra37. PMID 20460648 DOI: 10.1126/Scisignal.2000647  1
2010 Shen L, Caruso G, Bisegna P, Andreucci D, Gurevich VV, Hamm HE, DiBenedetto E. Dynamics of mouse rod phototransduction and its sensitivity to variation of key parameters Iet Systems Biology. 4: 12-32. PMID 20001089 DOI: 10.1049/Iet-Syb.2008.0154  1
2009 Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA. Suboptimal activation of protease-activated receptors enhances α 2β1 integrin-mediated platelet adhesion tocollagen Journal of Biological Chemistry. 284: 34640-34647. PMID 19815553 DOI: 10.1074/Jbc.M109.020990  1
2009 Hamm HE, Meier SM, Liao G, Preininger AM. Trp fluorescence reveals an activation-dependent cation-π interaction in the switch II region of Gαi proteins Protein Science. 18: 2326-2335. PMID 19760664 DOI: 10.1002/Pro.243  1
2009 Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE. Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates Molecular Pharmacology. 76: 301-313. PMID 19483102 DOI: 10.1124/Mol.109.056622  1
2009 Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, Marrs JA, Hamm HE, Solnica-Krezel L. Gα 12/i3 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton Journal of Cell Biology. 184: 909-921. PMID 19307601 DOI: 10.1083/Jcb.200805148  1
2009 Preininger AM, Funk MA, Oldham WM, Meier SM, Johnston CA, Adhikary S, Kimple AJ, Siderovski DP, Hamm HE, Iverson TM. Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits. Biochemistry. 48: 2630-42. PMID 19222191 DOI: 10.1021/Bi801853A  1
2009 Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL. Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors. Biophysical Journal. 96: 939-50. PMID 19186132 DOI: 10.1016/J.Bpj.2008.10.016  1
2009 Mazzoni MR, Porchia F, Hamm HE. Proteolytic fragmentation for epitope mapping Methods in Molecular Biology. 524: 77-86. DOI: 10.1007/978-1-59745-450-6_6  1
2008 Yoon EJ, Hamm HE, Currie KPM. G protein βγ subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry Journal of Neurophysiology. 100: 2929-2939. PMID 18815342 DOI: 10.1152/Jn.90839.2008  1
2008 Preininger AM, Parello J, Meier SM, Liao G, Hamm HE. Receptor-mediated changes at the myristoylated amino terminus of Gαil proteins Biochemistry. 47: 10281-10293. PMID 18771287 DOI: 10.1021/Bi800741R  1
2008 Chen S, Lin F, Myung ES, Wang F, Shen L, Hamm HE. RACK1 regulates directional cell migration by acting on gβγ at the interface with its effectors PLCβ and PI3Kγ Molecular Biology of the Cell. 19: 3909-3922. PMID 18596232 DOI: 10.1091/Mbc.E08-04-0433  1
2008 Bisegna P, Caruso G, Andreucci D, Shen L, Gurevich VV, Hamm HE, Dibenedetto E. Diffusion of the second messengers in the cytoplasm acts as a variability suppressor of the single photon response in vertebrate phototransduction Biophysical Journal. 94: 3363-3383. PMID 18400950 DOI: 10.1529/Biophysj.107.114058  1
2008 Oldham WM, Hamm HE. Heterotrimeric G protein activation by G-protein-coupled receptors Nature Reviews Molecular Cell Biology. 9: 60-71. PMID 18043707 DOI: 10.1038/Nrm2299  1
2007 Oldham WM, Hamm HE. How do Receptors Activate G Proteins? Advances in Protein Chemistry. 74: 67-93. PMID 17854655 DOI: 10.1016/S0065-3233(07)74002-0  1
2007 Yoon EJ, Gerachshenko T, Spiegelberg BD, Alford S, Hamm HE. Gbetagamma interferes with Ca2+-dependent binding of synaptotagmin to the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. Molecular Pharmacology. 72: 1210-9. PMID 17715396 DOI: 10.1124/Mol.107.039446  1
2007 Bilodeau ML, Hamm HE. Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions. The Journal of Pharmacology and Experimental Therapeutics. 322: 778-88. PMID 17525299 DOI: 10.1124/Jpet.107.121830  1
2007 Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 7927-32. PMID 17463080 DOI: 10.1073/Pnas.0702623104  1
2007 Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE. PAR1, but not PAR4, activates human platelets through a G i/o/phosphoinositide-3 kinase signaling axis Molecular Pharmacology. 71: 1399-1406. PMID 17303701 DOI: 10.1124/Mol.106.033365  1
2007 Huang K, Voss B, Kumar D, Hamm HE, Harth E. Dendritic molecular transporters provide control of delivery to intracellular compartments Bioconjugate Chemistry. 18: 403-409. PMID 17284011 DOI: 10.1021/Bc060287A  1
2007 Spiegelberg BD, Hamm HE. Roles of G-protein-coupled receptor signaling in cancer biology and gene transcription Current Opinion in Genetics and Development. 17: 40-44. PMID 17188489 DOI: 10.1016/J.Gde.2006.12.002  1
2007 Holinstat M, Voss B, Bilodeau ML, Hamm HE. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway. Molecular Pharmacology. 71: 686-94. PMID 17151288 DOI: 10.1124/Mol.106.029371  1
2006 Murphy SC, Harrison T, Hamm HE, Lomasney JW, Mohandas N, Haldar K. Erythrocyte G protein as a novel target for malarial chemotherapy. Plos Medicine. 3: e528. PMID 17194200 DOI: 10.1371/Journal.Pmed.0030528  1
2006 Van Eps N, Oldham WM, Hamm HE, Hubbell WL. Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 16194-9. PMID 17053066 DOI: 10.1073/Pnas.0607972103  1
2006 Chen S, Hamm HE. DEP Domains: More Than Just Membrane Anchors Developmental Cell. 11: 436-438. PMID 17011483 DOI: 10.1016/J.Devcel.2006.09.011  1
2006 Oldham WM, Hamm HE. Structural basis of function in heterotrimeric G proteins Quarterly Reviews of Biophysics. 39: 117-166. PMID 16923326 DOI: 10.1017/S0033583506004306  1
2006 Holinstat M, Oldham WM, Hamm HE. G-protein-coupled receptors: Evolving views on physiological signalling: Symposium on G-Protein-Coupled Receptors: Evolving Concepts and New Techniques Embo Reports. 7: 866-869. PMID 16906127 DOI: 10.1038/Sj.Embor.7400788  1
2006 Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. Nature Structural & Molecular Biology. 13: 772-7. PMID 16892066 DOI: 10.1038/Nsmb1129  1
2006 Holinstat M, Voss B, Bilodeau ML, McLaughlin JN, Cleator J, Hamm HE. PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation. The Journal of Biological Chemistry. 281: 26665-74. PMID 16837456 DOI: 10.1074/Jbc.M602174200  1
2006 Caruso G, Bisegna P, Shen L, Andreucci D, Hamm HE, DiBenedetto E. Modeling the role of incisures in vertebrate phototransduction Biophysical Journal. 91: 1192-1212. PMID 16714347 DOI: 10.1529/Biophysj.106.083618  1
2006 Ding J, Guzman JN, Tkatch T, Chen S, Goldberg JA, Ebert PJ, Levitt P, Wilson CJ, Hamm HE, Surmeier DJ. RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion. Nature Neuroscience. 9: 832-42. PMID 16699510 DOI: 10.1038/Nn1700  1
2006 Preininger AM, Henage LG, Oldham WM, Yoon EJ, Hamm HE, Brown HA. Direct modulation of phospholipase D activity by Gβγ Molecular Pharmacology. 70: 311-318. PMID 16638972 DOI: 10.1124/Mol.105.021451  1
2006 Photowala H, Blackmer T, Schwartz E, Hamm HE, Alford S. G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties. Proceedings of the National Academy of Sciences of the United States of America. 103: 4281-6. PMID 16537522 DOI: 10.1073/Pnas.0600509103  1
2006 Bilodeau ML, Hamm HE. Endothelial nitric-oxide synthase reveals a new face in G protein signaling. Molecular Pharmacology. 69: 677-9. PMID 16377762 DOI: 10.1124/Mol.105.022038  1
2006 Cleator JH, Zhu WQ, Vaughan DE, Hamm HE. Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP. Blood. 107: 2736-44. PMID 16332977 DOI: 10.1182/Blood-2004-07-2698  1
2005 Caruso G, Khanal H, Alexiades V, Rieke F, Hamm HE, DiBenedetto E. Mathematical and computational modelling of spatio-temporal signalling in rod phototransduction. Systems Biology. 152: 119-37. PMID 16986276 DOI: 10.1049/ip-syb:20050019  1
2005 Spiegelberg BD, Hamm HE. Gβγ binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activity Journal of Biological Chemistry. 280: 41769-41776. PMID 16221676 DOI: 10.1074/Jbc.M504066200  1
2005 Chen S, Lin F, Hamm HE. RACK1 binds to a signal transfer region of Gβγ and inhibits phospholipase C β2 activation Journal of Biological Chemistry. 280: 33445-33452. PMID 16051595 DOI: 10.1074/Jbc.M505422200  1
2005 Lin F, Sepich DS, Chen S, Topczewski J, Yin C, Solnica-Krezel L, Hamm H. Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. The Journal of Cell Biology. 169: 777-87. PMID 15928205 DOI: 10.1083/Jcb.200501104  1
2005 Lukov GL, Hu T, McLaughlin JN, Hamm HE, Willardson BM. Phosducin-like protein acts as a molecular chaperone for G protein βγ dimer assembly Embo Journal. 24: 1965-1975. PMID 15889144 DOI: 10.1038/Sj.Emboj.7600673  1
2005 McLaughlin JN, Shen L, Holinstat M, Brooks JD, DiBenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1 Journal of Biological Chemistry. 280: 25048-25059. PMID 15878870 DOI: 10.1074/Jbc.M414090200  1
2005 Gerachshenko T, Blackmer T, Yoon EJ, Bartleson C, Hamm HE, Alford S. Gbetagamma acts at the C terminus of SNAP-25 to mediate presynaptic inhibition. Nature Neuroscience. 8: 597-605. PMID 15834421 DOI: 10.1038/Nn1439  1
2005 McLaughlin JN, Mazzoni MR, Cleator JH, Earls L, Perdigoto AL, Brooks JD, Muldowney JA, Vaughan DE, Hamm HE. Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells. The Journal of Biological Chemistry. 280: 22172-80. PMID 15817447 DOI: 10.1074/Jbc.M500721200  1
2005 Shen L, Andreucci D, Hamm HE, Dibenedetto E. Fluctuations of the single photon response in visual transduction Aip Conference Proceedings. 780: 553-556. DOI: 10.1063/1.2036813  1
2004 Cabrera-Vera TM, Hernandez S, Earls LR, Medkova M, Sundgren-Andersson AK, Surmeier DJ, Hamm HE. RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneurons. Proceedings of the National Academy of Sciences of the United States of America. 101: 16339-44. PMID 15534226 DOI: 10.1073/Pnas.0407416101  1
2004 Chen S, Spiegelberg BD, Lin F, Dell EJ, Hamm HE. Interaction of Gβγ with RACK1 and other WD40 repeat proteins Journal of Molecular and Cellular Cardiology. 37: 399-406. PMID 15276010 DOI: 10.1016/J.Yjmcc.2004.04.019  1
2004 Chen S, Dell EJ, Lin F, Sai J, Hamm HE. RACK1 Regulates Specific Functions of Gβγ Journal of Biological Chemistry. 279: 17861-17868. PMID 14963031 DOI: 10.1074/Jbc.M313727200  1
2004 Preininger AM, Hamm HE. G protein signaling: insights from new structures. Science's Stke : Signal Transduction Knowledge Environment. 2004: re3. PMID 14762218 DOI: 10.1126/Stke.2182004Re3  1
2003 Cabrera-Vera TM, Vanhauwe J, Thomas TO, Medkova M, Preininger A, Mazzoni MR, Hamm HE. Insights into G Protein Structure, Function, and Regulation Endocrine Reviews. 24: 765-781. PMID 14671004 DOI: 10.1210/Er.2000-0026  1
2003 Slessareva JE, Ma H, Depree KM, Flood LA, Bae H, Cabrera-Vera TM, Hamm HE, Graber SG. Closely Related G-protein-coupled Receptors Use Multiple and Distinct Domains on G-protein α-Subunits for Selective Coupling Journal of Biological Chemistry. 278: 50530-50536. PMID 14525988 DOI: 10.1074/Jbc.M304417200  1
2003 Harrison T, Samuel BU, Akompong T, Hamm H, Mohandas N, Lomasney JW, Haldar K. Erythrocyte G protein-coupled receptor signaling in malarial infection. Science (New York, N.Y.). 301: 1734-6. PMID 14500986 DOI: 10.1126/Science.1089324  1
2003 Andreucci D, Bisegna P, Caruso G, Hamm HE, DiBenedetto E. Mathematical model of the spatio-temporal dynamics of second messengers in visual transduction Biophysical Journal. 85: 1358-1376. PMID 12944255 DOI: 10.1016/S0006-3495(03)74570-6  1
2003 Preininger AM, Van Eps N, Yu NJ, Medkova M, Hubbell WL, Hamm HE. The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution. Biochemistry. 42: 7931-41. PMID 12834345 DOI: 10.1021/Bi0345438  1
2003 Chen NF, Yu JZ, Skiba NP, Hamm HE, Rasenick MM. A specific domain of Giα required for the transactivation of Giα by tubulin is implicated in the organization of cellular microtubules Journal of Biological Chemistry. 278: 15285-15290. PMID 12582171 DOI: 10.1074/Jbc.M300841200  1
2002 Dell EJ, Connor J, Chen S, Stebbins EG, Skiba NP, Moehly-Rosen D, Hamm HE. The βγ subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins Journal of Biological Chemistry. 277: 49888-49895. PMID 12359736 DOI: 10.1074/Jbc.M202755200  1
2002 Medkova M, Preininger AM, Yu NJ, Hubbell WL, Hamm HE. Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation. Biochemistry. 41: 9962-72. PMID 12146960 DOI: 10.1021/Bi0255726  1
2002 Vanhauwe JF, Thomas TO, Minshall RD, Tiruppathi C, Li A, Gilchrist A, Yoon EJ, Malik AB, Hamm HE. Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes. The Journal of Biological Chemistry. 277: 34143-9. PMID 12039967 DOI: 10.1074/Jbc.M204477200  1
2002 Mukherjee S, Gurevich VV, Preninger A, Hamm HE, Bader MF, Fazleabas AT, Birnbaumer L, Hunzicker-Dunn M. Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2. The Journal of Biological Chemistry. 277: 17916-27. PMID 11867621 DOI: 10.1074/Jbc.M110479200  1
2002 Gilchrist A, Li A, Hamm HE. G alpha COOH-terminal minigene vectors dissect heterotrimeric G protein signaling. Science's Stke : Signal Transduction Knowledge Environment. 2002: pl1. PMID 11836477 DOI: 10.1126/Stke.2002.118.Pl1  1
2002 Schey KL, Busman M, Cook LA, Hamm HE, Hildebrandt JD. Structural characterization of intact G protein gamma subunits by mass spectrometry. Methods in Enzymology. 344: 586-97. PMID 11771413 DOI: 10.1016/S0076-6879(02)44742-8  1
2002 Gilchrist A, Li A, Hamm HE. Design and use of C-terminal minigene vectors for studying role of heterotrimeric G proteins. Methods in Enzymology. 344: 58-69. PMID 11771412 DOI: 10.1016/S0076-6879(02)44705-2  1
2002 Dell EJ, Blackmer T, Skiba NP, Daaka Y, Shekter LR, Rosal R, Reuveny E, Hamm HE. Defining G protein beta gamma specificity for effector recognition. Methods in Enzymology. 344: 421-34. PMID 11771401 DOI: 10.1016/S0076-6879(02)44731-3  1
2001 Cabrera-Vera TM, Thomas TO, Vanhauwe J, Depree KM, Graber SG, Hamm HE. Dissecting receptor-G protein specificity using Gα chimeras Methods in Enzymology. 344: 69-81. PMID 11771421 DOI: 10.1016/S0076-6879(02)44706-4  1
2001 Thomas TO, Bae H, Medkova M, Hamm HE. An intramolecular contact in Gα transducin that participates in maintaining its intrinsic GDP release rate Molecular Cell Biology Research Communications. 4: 282-291. PMID 11529678 DOI: 10.1006/Mcbr.2001.0293  1
2001 Salvador LM, Mukherjee S, Kahn RA, Lamm MLG, Fazleabas AT, Maizels ET, Bader MF, Hamm H, Rasenick MM, Casanova JE, Hunzieker-Dunn M. Activation of the Luteinizing Hormone/Choriogonadotropin Hormone Receptor Promotes ADP Ribosylation Factor 6 Activation in Porcine Ovarian Follicular Membranes Journal of Biological Chemistry. 276: 33773-33781. PMID 11448949 DOI: 10.1074/Jbc.M101498200  1
2001 Minadeo N, Layden B, Amari LV, Thomas V, Radloff K, Srinivasan C, Hamm HE, de Freitas DM. Effect of Li+ upon the Mg2+-dependent activation of recombinant Gialpha1. Archives of Biochemistry and Biophysics. 388: 7-12. PMID 11361143 DOI: 10.1006/Abbi.2001.2282  1
2001 Thulin CD, Savage JR, McLaughlin JN, Truscott SM, Old WM, Ahn NG, Resing KA, Hamm HE, Bitensky MW, Willardson BM. Modulation of the G Protein Regulator Phosducin by Ca 2+/Calmodulin-dependent Protein Kinase II Phosphorylation and 14-3-3 Protein Binding Journal of Biological Chemistry. 276: 23805-23815. PMID 11331285 DOI: 10.1074/Jbc.M101482200  1
2001 Hamm HE. How activated receptors couple to G proteins Proceedings of the National Academy of Sciences of the United States of America. 98: 4819-4821. PMID 11320227 DOI: 10.1073/Pnas.011099798  1
2001 Blackmer T, Larsen EC, Takahashi M, Martin TF, Alford S, Hamm HE. G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry. Science (New York, N.Y.). 292: 293-7. PMID 11303105 DOI: 10.1126/Science.1058803  1
2001 Gilchrist A, Vanhauwe JF, Li A, Thomas TO, Voyno-Yasenetskaya T, Hamm HE. G alpha minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation. The Journal of Biological Chemistry. 276: 25672-9. PMID 11274183 DOI: 10.1074/Jbc.M100914200  1
2001 Lopez I, Mak EC, Ding J, Hamm HE, Lomasney JW. A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 276: 2758-65. PMID 11022047 DOI: 10.1074/Jbc.M008119200  1
2001 Aris L, Gilchrist A, Rens-Domiano S, Meyer C, Schatz PJ, Dratz EA, Hamm HE. Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin. The Journal of Biological Chemistry. 276: 2333-9. PMID 11018024 DOI: 10.1074/Jbc.M002533200  1
2000 Minshall RD, Tiruppathi C, Vogel SM, Niles WD, Gilchrist A, Hamm HE, Malik AB. Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway. The Journal of Cell Biology. 150: 1057-70. PMID 10973995 DOI: 10.1083/Jcb.150.5.1057  1
2000 Savage JR, McLaughlin JN, Skiba NP, Hamm HE, Willardson BM. Functional roles of the two domains of phosducin and phosducin-like protein. The Journal of Biological Chemistry. 275: 30399-407. PMID 10896945 DOI: 10.1074/Jbc.M005120200  1
2000 Mazzoni MR, Taddei S, Giusti L, Rovero P, Galoppini C, D'Ursi A, Albrizio S, Triolo A, Novellino E, Greco G, Lucacchini A, Hamm HE. A Gα(s) carboxyl-terminal peptide prevents G(s) activation by the A(2A) adenosine receptor Molecular Pharmacology. 58: 226-236. PMID 10860945 DOI: 10.1124/Mol.58.1.226  1
2000 Skiba NP, Thomas TO, Hamm HE. Gα(t)/Gα(i1) chimeras used to define structural basis of specific functions of Gα(t) Methods in Enzymology. 315: 502-524. PMID 10736723 DOI: 10.1016/S0076-6879(00)15864-1  1
2000 Yang CS, Skiba NP, Mazzoni MR, Thomas TO, Hamm HE. Fluorescent probes as indicators of conformation changes in transducin on activation Methods in Enzymology. 315: 490-502. PMID 10736722 DOI: 10.1016/S0076-6879(00)15863-X  1
2000 Gilchrist A, Li A, Hamm HE. Use of peptides-on-plasmids combinatorial library to identify high-affinity peptides that bind rhodopsin. Methods in Enzymology. 315: 388-404. PMID 10736715 DOI: 10.1016/S0076-6879(00)15856-2  1
1999 Bae H, Cabrera-Vera TM, Depree KM, Graber SG, Hamm HE. Two amino acids within the helix of Gα(i1) mediate coupling with 5- hydroxytryptamine(1B) receptors Journal of Biological Chemistry. 274: 14963-14971. PMID 10329698 DOI: 10.1074/Jbc.274.21.14963  1
1999 Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 274: 13718-27. PMID 10224146 DOI: 10.1074/Jbc.274.19.13718  1
1999 Rajagopalan-Gupta RM, Mukherjee S, Zhu X, Ho YK, Hamm H, Birnbaumer M, Birnbaumer L, Hunzicker-Dunn M. Roles of Gi and Gq/11 in mediating desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes. Endocrinology. 140: 1612-21. PMID 10098495 DOI: 10.1210/Endo.140.4.6657  1
1999 Skiba NP, Yang CS, Huang T, Bae H, Hamm HE. The α-helical domain of Gα(t) determines specific interaction with regulator of G protein signaling 9 Journal of Biological Chemistry. 274: 8770-8778. PMID 10085118 DOI: 10.1074/Jbc.274.13.8770  1
1999 Gilchrist A, Bünemann M, Li A, Hosey MM, Hamm HE. A dominant-negative strategy for studying roles of G proteins in vivo. The Journal of Biological Chemistry. 274: 6610-6. PMID 10037756 DOI: 10.1074/Jbc.274.10.6610  1
1999 Yang CS, Skiba NP, Mazzoni MR, Hamm HE. Conformational changes at the carboxyl terminus of Gα occur during G protein activation Journal of Biological Chemistry. 274: 2379-2385. PMID 9891006 DOI: 10.1074/Jbc.274.4.2379  1
1998 Gilchrist A, Mazzoni MR, Dineen B, Dice A, Linden J, Proctor WR, Lupica CR, Dunwiddie TV, Hamm HE. Antagonists of the receptor-G protein interface block Gi-coupled signal transduction. The Journal of Biological Chemistry. 273: 14912-9. PMID 9614095 DOI: 10.1074/Jbc.273.24.14912  1
1998 Ford CE, Skiba NP, Bae H, Daaka Y, Reuveny E, Shekter LR, Rosal R, Weng G, Yang CS, Iyengar R, Miller RJ, Jan LY, Lefkowitz RJ, Hamm HE. Molecular basis for interactions of G protein betagamma subunits with effectors. Science (New York, N.Y.). 280: 1271-4. PMID 9596582 DOI: 10.1126/Science.280.5367.1271  1
1998 Skiba NP, Hamm HE. How Gsα activates adenylyl cyclase Nature Structural Biology. 5: 88-92. PMID 9461067 DOI: 10.1038/Nsb0298-88  1
1998 Hamm HE. The many faces of G protein signaling Journal of Biological Chemistry. 273: 669-672. PMID 9422713 DOI: 10.1074/Jbc.273.2.669  1
1997 Bae H, Anderson K, Flood LA, Skiba NP, Hamm HE, Graber SG. Molecular determinants of selectivity in 5-hydroxytryptamine(1B) receptor-G protein interactions Journal of Biological Chemistry. 272: 32071-32077. PMID 9405403 DOI: 10.1074/Jbc.272.51.32071  1
1997 Nekrasova ER, Berman DM, Rustandi RR, Hamm HE, Gilman AG, Arshavsky VY. Activation of transducin guanosine triphosphatase by two proteins of the RGS family Biochemistry. 36: 7638-7643. PMID 9201904 DOI: 10.1021/Bi970427R  1
1997 Nekrasova ER, Berman DM, Rustandi RR, Hamm HE, Gilman AC, Arshavsky VY. Activation of transducin gtpase by two proteins from the rgs family Investigative Ophthalmology and Visual Science. 38: S477.  1
1997 Bae H, Anderson K, Flood LA, Skiba NP, Hamm HE, Gräber SG. Molecular Determinants of Selectivity in Receptor-G protein Interaction Faseb Journal. 11: A1340.  1
1997 Ford CE, Bae H, Skiba NP, Hamm HE. Molecular basis for Gβy-dependent interactions Faseb Journal. 11: A1340.  1
1996 Mazzoni MR, Hamm HE. Interaction of transducin with light-activated rhodopsin protects it from proteolytic digestion by trypsin Journal of Biological Chemistry. 271: 30034-30040. PMID 8939950 DOI: 10.1074/Jbc.271.47.30034  1
1996 Artemyev NO, Surendran R, Lee JC, Hamm HE. Subunit structure of rod cGMP-phosphodiesterase Journal of Biological Chemistry. 271: 25382-25388. PMID 8810304 DOI: 10.1074/Jbc.271.41.25382  1
1996 Hamm HE, Gilchrist A. Heterotrimeric G proteins. Current Opinion in Cell Biology. 8: 189-96. PMID 8791425 DOI: 10.1016/S0955-0674(96)80065-2  1
1996 Artemyev NO, Natochin M, Busman M, Schey KL, Hamm HE. Mechanism of photoreceptor cGMP phosphodiesterase inhibition by its γ-subunits Proceedings of the National Academy of Sciences of the United States of America. 93: 5407-5412. PMID 8643588 DOI: 10.1073/Pnas.93.11.5407  1
1996 Suh KH, Hamm HE. Cyclic AMP-dependent phosphoprotein components I and II interact with βγ subunits of transducin in frog rod outer segments Biochemistry. 35: 290-298. PMID 8555187 DOI: 10.1021/Bi9518656  1
1996 Sondek J, Bohm A, Lambright DG, Hamm HE, Sigler PB. Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. Nature. 379: 369-74. PMID 8552196 DOI: 10.1038/379369A0  1
1996 Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE, Sigler PB. The 2.0 A crystal structure of a heterotrimeric G protein. Nature. 379: 311-9. PMID 8552184 DOI: 10.1038/379311A0  1
1996 Skiba NP, Bae H, Hamm HE. Mapping of effector binding sites of transducin α-subunit using Gαt/Gαi1 chimeras Journal of Biological Chemistry. 271: 413-424. PMID 8550597 DOI: 10.1074/Jbc.271.1.413  1
1996 Martin EL, Rens-Domiano S, Schatz PJ, Hamm HE. Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library Journal of Biological Chemistry. 271: 361-366. PMID 8550587 DOI: 10.1074/Jbc.271.1.361  1
1996 Hamm HE. Structure and function of a heterotrimeric G protein Faseb Journal. 10: A999.  1
1995 Slepak VZ, Artemyev NO, Zhu Y, Dumke CL, Sabacan L, Sondek J, Hamm HE, Bownds MD, Arshavsky VY. An effector site that stimulates G-protein GTPase in photoreceptors Journal of Biological Chemistry. 270: 14319-14324. PMID 7782290 DOI: 10.1074/Jbc.270.24.14319  1
1995 Skiba NP, Artemyev NO, Hamm HE. The carboxyl terminus of the γ-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the α-subunit of transducin Journal of Biological Chemistry. 270: 13210-13215. PMID 7768919 DOI: 10.1074/Jbc.270.22.13210  1
1995 Rens-Domiano S, Hamm HE. Structural and functional relationships of heterotrimeric G-proteins Faseb Journal. 9: 1059-1066. DOI: 10.1096/Fasebj.9.11.7649405  1
1994 Lambright DG, Noel JP, Hamm HE, Sigler PB. Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein. Nature. 369: 621-8. PMID 8208289 DOI: 10.1038/369621A0  1
1994 Krupnick JG, Gurevich VV, Schepers T, Hamm HE, Benovic JL. Arrestin-rhodopsin interaction: Multi-site binding delineated by peptide inhibition Journal of Biological Chemistry. 269: 3226-3232. PMID 8106358  1
1994 Rasenick MM, Watanabe M, Lazarevic MB, Hatta S, Hamm HE. Synthetic peptides as probes for G protein function: Carboxyl-terminal Gαs peptides mimic Gs and evoke high affinity agonist binding to β-adrenergic receptors Journal of Biological Chemistry. 269: 21519-21525. PMID 8063788  1
1994 Arshavsky VY, Dumke CL, Zhu Y, Artemyev NO, Skiba NP, Hamm HE, Bownds MD. Regulation of transducin GTPase activity in bovine rod outer segments Journal of Biological Chemistry. 269: 19882-19887. PMID 8051070  1
1994 Sondek J, Lambright DG, Noel JP, Hamm HE, Sigler PB. GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4. Nature. 372: 276-9. PMID 7969474 DOI: 10.1038/372276A0  1
1994 Hamm HE, Rarick HM. [32] Specific peptide probes for G-protein interactions with receptors Methods in Enzymology. 237: 423-436. PMID 7935015 DOI: 10.1016/S0076-6879(94)37079-6  1
1994 Rarick HM, Artemyev NO, Mills JS, Skiba NP, Hamm HE. Specific peptide probes for G-protein interaction with effectors Methods in Enzymology. 238: 13-28. PMID 7799779 DOI: 10.1016/0076-6879(94)38004-X  1
1994 Artemyev NO, Hamm HE. Probing G-protein function Nature Structural Biology. 1: 752-754. PMID 7634081 DOI: 10.1038/Nsb1194-752  1
1993 Mazzoni MR, Hamm HE. Tryptophan207 is involved in the GTP-dependent conformational switch in the α subunit of the G protein transducin: Chymotryptic digestion patterns of the GTPγS and GDP-bound forms Journal of Protein Chemistry. 12: 215-221. PMID 8489707 DOI: 10.1007/Bf01026043  1
1993 Dratz EA, Furstenau JE, Lambert CG, Thireault DL, Rarick H, Schepers T, Pakhlevaniants S, Hamm HE. NMR structure of a receptor-bound G-protein peptide Nature. 363: 276-281. PMID 8487866 DOI: 10.1038/363276A0  1
1993 Hargrave PA, Hamm HE, Hofmann KP. Interaction of rhodopsin with the G-protein, transducin Bioessays. 15: 43-50. PMID 8466475 DOI: 10.1002/Bies.950150107  1
1993 Noel JP, Hamm HE, Sigler PB. The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S. Nature. 366: 654-63. PMID 8259210 DOI: 10.1038/366654A0  1
1993 Artemyev NO, Mills JS, Thornburg KR, Knapp DR, Schey KL, Hamm HE. A site on transducin α-subunit of interaction with the polycationic region of cGMP phosphodiesterase inhibitory subunit Journal of Biological Chemistry. 268: 23611-23615. PMID 8226888  1
1993 Rasenick MM, Lazarevic M, Watanabe M, Hamm HE. Permeable Cell Systems as Models for Studying Disruption, by Site-Specific Synthetic Peptides, of Receptor-G Protein-Effector Coupling Methods. 5: 252-257. DOI: 10.1006/Meth.1993.1031  1
1993 Artemyev NO, Skiba NP, Mills JS, Hamm HE. Rod cGMP-Phosphodiesterase γ-Subunit: Structure-Function Relationships Methods. 5: 220-228. DOI: 10.1006/Meth.1993.1027  1
1992 Mangels LA, Neubig RR, Hamm HE, Gnegy ME. Calmodulin binding distinguishes between βγ subunits of activated G proteins and transducin Biochemical Journal. 283: 683-690. PMID 1590758 DOI: 10.1042/Bj2830683  1
1992 Artemyev NO, Rarick HM, Mills JS, Skiba NP, Hamm HE. Sites of interaction between rod G-protein α-subunit and cGMP-phosphodiesterase γ-subunit: Implications for the phosphodiesterase activation mechanism Journal of Biological Chemistry. 267: 25067-25072. PMID 1334079  1
1992 Rarick HM, Artemyev NO, Hamm HE. A site on rod G protein α subunit that mediates effector activation Science. 256: 1031-1033. PMID 1317058 DOI: 10.1126/Science.1317058  1
1992 Artemyev NO, Hamm HE. Two-site high-affinity interaction between inhibitory and catalytic subunits of rod cyclic GMP phosphodiesterase Biochemical Journal. 283: 273-279. PMID 1314566 DOI: 10.1042/Bj2830273  1
1992 Stieve H, Niemeyer B, Aktories K, Hamm HE. Disturbing gtp-binding protein function through microinjection into the visual cell of limulus Zeitschrift Fur Naturforschung - Section C Journal of Biosciences. 47: 915-921. PMID 1285831 DOI: 10.1515/Znc-1992-11-1220  1
1991 Warpeha KMF, Hamm HE, Rasenick MM, Kaufman LS. A blue-light-activated GTP-binding protein in the plasma membranes of etiolated peas Proceedings of the National Academy of Sciences of the United States of America. 88: 8925-8929. PMID 1924352 DOI: 10.1073/Pnas.88.20.8925  1
1991 Hamm HE. Molecular interactions between the photoreceptor G protein and rhodopsin Cellular and Molecular Neurobiology. 11: 563-578. PMID 1782650 DOI: 10.1007/Bf00741446  1
1991 Mazzoni MR, Malinski JA, Hamm HE. Structural analysis of rod GTP-binding protein, Gt: Limited proteolytic digestion pattern of G, with four proteases defines monoclonal antibody epitope Journal of Biological Chemistry. 266: 14072-14081. PMID 1713215  1
1990 Hamm HE, Rarick H, Mazzoni M, Malinski J, Suh KH. The molecular basis of GTP-binding protein interaction with receptors Biochemical Society Symposia. 56: 35-44. PMID 2256961  1
1990 Robinson PR, Wood SF, Szuts EZ, Fein A, Hamm HE, Lisman JE. Light-dependent GTP-binding proteins in squid photoreceptors. The Biochemical Journal. 272: 79-85. PMID 2124806 DOI: 10.1042/Bj2720079  1
1990 Hamm HE. Surfaces of interaction between Gt and rhodopsin in the GDP-bound and empty-pocket configurations Advances in Second Messenger and Phosphoprotein Research. 24: 76-82. PMID 2119661  1
1989 Hamm HE, Deretic D, Mazzoni MR, Moore CA, Takahashi JS, Rasenick MM. A monoclonal antibody against the rod outer segment guanyl nucleotide-binding protein, transducin, blocks the stimulatory and inhibitory G proteins of adenylate cyclase. The Journal of Biological Chemistry. 264: 11475-82. PMID 2544596  1
1989 Mazzoni MR, Hamm HE. Effect of monoclonal antibody binding on α-βγ subunit interactions in the rod outer segment G protein, Gt Biochemistry. 28: 9873-9880. PMID 2482080 DOI: 10.1021/Bi00451A047  1
1989 Birnbaumer L, Codina J, Yatani A, Mattera R, Graf R, Olate J, Themmen AP, Liao CF, Sanford J, Okabe K. Molecular basis of regulation of ionic channels by G proteins. Recent Progress in Hormone Research. 45: 121-206; discussion . PMID 2479060 DOI: 10.1016/B978-0-12-571145-6.50008-X  1
1989 Pepe IM, Panfoli I, Hamm HE. Visual transduction in vertebrate photoreceptors - Light activation of guanylate cyclase Cell Biophysics. 14: 129-137. PMID 2472205 DOI: 10.1007/BF02797130  1
1988 Hamm HE, Deretic D, Arendt A, Hargrave PA, Koenig B, Hofmann KP. Site of G protein binding to rhodopsin mapped with synthetic peptides from the α subunit Science. 241: 832-835. PMID 3136547 DOI: 10.1126/Science.3136547  1
1987 Deretic D, Hamm HE. Topographic analysis of antigenic determinants recognized by monoclonal antibodies to the photoreceptor guanyl nucleotide-binding protein, transducin Journal of Biological Chemistry. 262: 10839-10847. PMID 2440876  1
1987 Hamm HE, Deretic D, Hofmann KP, Schleicher A, Kohl B. Mechanism of action of monoclonal antibodies that block the light activation of the guanyl nucleotide-binding protein, transducin Journal of Biological Chemistry. 262: 10831-10838. PMID 2440875  1
1986 Hamm HE, Deric Bownds M. Protein complement of rod outer segments of frog retina Biochemistry®. 25: 4512-4523. PMID 3021191 DOI: 10.1021/Bi00364A010  1
1984 Witt PL, Hamm HE, Bownds MD. Preparation and characterization of monoclonal antibodies to several frog rod outer segment proteins Journal of General Physiology. 84: 251-263. PMID 6387041 DOI: 10.1085/Jgp.84.2.251  1
1984 Hamm HE, Bownds MD. A monoclonal antibody to guanine necleotide binding protein inhibits the light-activated cyclic GMP pathway in frog rod outer segments Journal of General Physiology. 84: 265-280. PMID 6092516 DOI: 10.1085/Jgp.84.2.265  1
1983 Hamm HE, Takahashi JS, Menaker M. Light-induced decrease of serotonin N-acetyltransferase activity and melatonin in the chicken pineal gland and retina. Brain Research. 266: 287-93. PMID 6871664 DOI: 10.1016/0006-8993(83)90660-1  1
1982 Hermolin J, Karell MA, Hamm HE, Bownds MD. Calcium and cyclic GMP regulation of light-sensitive protein phosphorylation in frog photoreceptor membranes Journal of General Physiology. 79: 633-655. PMID 6279759 DOI: 10.1085/Jgp.79.4.633  1
1981 Hamm HE, Menaker M. Pineal and retinal serotonin N-acetyltransferase activity: modulation by phosphate. Journal of Neurochemistry. 37: 1567-72. PMID 7334376 DOI: 10.1111/J.1471-4159.1981.Tb06328.X  1
1980 Goldman ME, Hamm H, Erickson CK. Determination of melatonin by high-performance liquid chromatography with electrochemical detection Journal of Chromatography A. 190: 217-220. PMID 7380947 DOI: 10.1016/S0021-9673(00)85537-5  1
1980 Hamm HE, Menaker M. Retinal rhythms in chicks: circadian variation in melantonin and serotonin N-acetyltransferase activity. Proceedings of the National Academy of Sciences of the United States of America. 77: 4998-5002. PMID 6933543 DOI: 10.1073/Pnas.77.8.4998  1
1980 Takahashi JS, Hamm H, Menaker M. Circadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro. Proceedings of the National Academy of Sciences of the United States of America. 77: 2319-22. PMID 6929552 DOI: 10.1073/Pnas.77.4.2319  1
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